Title: Insecticide-Insensitive Acetylcholinesterase Can Enhance Esterase-Based Resistance in Myzus persicae and Myzus nicotianae
Abstract: The acetylcholinesterase in some resistant strains of Myzus persicae and its extremely close relative Myzus nicotianae showed marked insensitivity to inhibition by the established carbamate pirimicarb (>100-fold) and by triazamate, a novel triazole aphicide (>10-fold), that acts on the same target. There was no insensitivity to a range of other carbamate and organophosphorus insecticides. This resistance mechanism appears to be rare at present and was only found in a heterozygous form associated with the commonly occurring elevated E4/FE4 esterases that confer broad cross-resistance to many aphicides. This insensitive target site mechanism, even when heterozygous, enhances the esterase-based resistance to pirimicarb and triazamate by 15- to 30-fold.
Publication Year: 1994
Publication Date: 1994-06-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 137
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