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'important': [13, 167], 'negative': [14], 'regulator': [15], 'of': [16, 32, 42, 54, 64, 73, 91, 100, 120, 144, 193], 'T-cell': [17, 58, 188], 'function.': [18], 'In': [19, 47, 151], 'this': [20, 152], 'report,': [21], 'we': [22], 'demonstrate': [23, 178], 'that': [24, 179], 'A2AR': [25, 55, 75, 92, 111, 128, 154, 184], 'stimulation': [26, 112], 'not': [27, 130], 'only': [28, 131], 'inhibits': [29, 113, 132], 'generation': [31, 138, 143, 192], 'adaptive': [33, 43, 194], 'effector': [34, 136], 'T': [35, 45, 66, 149, 163, 196], 'cells': [36, 67], 'but': [37, 139], 'also': [38, 140], 'promotes': [39, 104, 141], 'induction': [41], 'regulatory': [44, 148, 195], 'cells.': [46, 150, 197], 'vitro,': [48], 'antigen': [49], 'recognition': [50], 'in': [51, 61, 70, 88, 95, 97, 171], 'setting': [53], 'engagement': [56], 'induces': [57], 'anergy,': [59], 'even': [60], 'presence': [63, 72], 'costimulation.': [65], 'initially': [68], 'stimulated': [69], 'agonist': [76], 'fail': [77, 156], 'to': [78, 157, 185], 'proliferate': [79], 'and': [80, 83, 106, 134, 146, 190], 'produce': [81], 'interleukin-2': [82], 'interferon': [84], '(IFN)-γ': [85], 'when': [86], 'rechallenged': [87], 'absence': [90], 'stimulation.': [93], 'Likewise,': [94], 'vivo': [98], 'model': [99], 'autoimmunity,': [101], 'tissue-derived': [102], 'anergy': [105, 189], 'abrogates': [107], 'tissue': [108], 'destruction.': [109], 'Indeed,': [110], 'interleukin-6': [114], 'expression': [115], 'while': [116], 'enhancing': [117], 'production': [119], 'transforming': [121], 'growth': [122], 'factor-β.': [123], 'Accordingly,': [124], 'treating': [125], 'mice': [126], 'with': [127], 'agonists': [129, 155], 'Th1': [133], 'Th17': [135], 'cell': [137], 'Foxp3+': [145], 'LAG-3+': [147], 'regard,': [153], 'prevent': [158], 'autoimmunity': [159], 'by': [160], 'LAG-3−/−': [161], 'clonotypic': [162], 'cells,': [164], 'implicating': [165], 'role': [168], 'for': [169], 'LAG-3': [170], 'adenosine-mediated': [172], 'peripheral': [173], 'tolerance.': [174], 'Overall,': [175], 'our': [176], 'findings': [177], 'extracellular': [180], 'stimulates': [182], 'promote': [186], 'long-term': [187]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1977187462', 'counts_by_year': [{'year': 2024, 'cited_by_count': 15}, {'year': 2023, 'cited_by_count': 27}, {'year': 2022, 'cited_by_count': 38}, {'year': 2021, 'cited_by_count': 27}, {'year': 2020, 'cited_by_count': 46}, {'year': 2019, 'cited_by_count': 29}, {'year': 2018, 'cited_by_count': 33}, {'year': 2017, 'cited_by_count': 32}, {'year': 2016, 'cited_by_count': 33}, {'year': 2015, 'cited_by_count': 34}, {'year': 2014, 'cited_by_count': 21}, {'year': 2013, 'cited_by_count': 24}, {'year': 2012, 'cited_by_count': 33}], 'updated_date': '2024-09-08T18:54:56.223479', 'created_date': '2016-06-24'}