Publication Information

{'id': 'https://openalex.org/W1977186839', 'doi': 'https://doi.org/10.1097/hjh.0b013e3283455ca5', 'title': 'A double-blind, randomized study comparing the antihypertensive effect of eplerenone and spironolactone in patients with hypertension and evidence of primary aldosteronism', 'display_name': 'A double-blind, randomized study comparing the antihypertensive effect of eplerenone and spironolactone in patients with hypertension and evidence of primary aldosteronism', 'publication_year': 2011, 'publication_date': '2011-03-30', 'ids': {'openalex': 'https://openalex.org/W1977186839', 'doi': 'https://doi.org/10.1097/hjh.0b013e3283455ca5', 'mag': '1977186839', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21451421'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/hjh.0b013e3283455ca5', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S115964404', 'display_name': 'Journal of Hypertension', 'issn_l': '0263-6352', 'issn': ['0263-6352', '1473-5598'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5085365659', 'display_name': 'Hari Parthasarathy', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2799766170', 'display_name': 'Papworth Hospital', 'ror': 'https://ror.org/05mqgrb58', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799766170', 'https://openalex.org/I4210104974']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Hari K Parthasarathy', 'raw_affiliation_strings': ['Department of Cardiology , Papworth Hospital , Cambridge , UK.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology , Papworth Hospital , Cambridge , UK.', 'institution_ids': ['https://openalex.org/I2799766170']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111841169', 'display_name': 'Joël Ménard', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210109141', 'display_name': 'Hôpital Européen', 'ror': 'https://ror.org/01tfhsg94', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210109141']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Joel Ménard', 'raw_affiliation_strings': ['Hôpital européen Georges Pompidou'], 'affiliations': [{'raw_affiliation_string': 'Hôpital européen Georges Pompidou', 'institution_ids': ['https://openalex.org/I4210109141']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056816871', 'display_name': 'William B. White', 'orcid': 'https://orcid.org/0000-0001-8936-967X'}, 'institutions': [], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'William B White', 'raw_affiliation_strings': ['University of Connecticut'], 'affiliations': [{'raw_affiliation_string': 'University of Connecticut', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057382848', 'display_name': 'William F. Young', 'orcid': 'https://orcid.org/0000-0001-5481-4884'}, 'institutions': [{'id': 'https://openalex.org/I4210166718', 'display_name': 'Institute of Nutrition, Metabolism and Diabetes', 'ror': 'https://ror.org/05nct1z71', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I176337269', 'https://openalex.org/I4210166718']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'William F Young', 'raw_affiliation_strings': ['Endocrinology, Diabetes, Metabolism, and Nutrition'], 'affiliations': [{'raw_affiliation_string': 'Endocrinology, Diabetes, Metabolism, and Nutrition', 'institution_ids': ['https://openalex.org/I4210166718']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047140893', 'display_name': 'Gordon H. Williams', 'orcid': 'https://orcid.org/0000-0002-4804-1093'}, 'institutions': [{'id': 'https://openalex.org/I1283280774', 'display_name': "Brigham and Women's Hospital", 'ror': 'https://ror.org/04b6nzv94', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1283280774', 'https://openalex.org/I48633490']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Gordon H Williams', 'raw_affiliation_strings': ["Brigham and Women's Hospital"], 'affiliations': [{'raw_affiliation_string': "Brigham and Women's Hospital", 'institution_ids': ['https://openalex.org/I1283280774']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017971948', 'display_name': 'Bryan Williams', 'orcid': 'https://orcid.org/0000-0002-8094-1841'}, 'institutions': [{'id': 'https://openalex.org/I153648349', 'display_name': 'University of Leicester', 'ror': 'https://ror.org/04h699437', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I153648349']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Bryan Williams', 'raw_affiliation_strings': ['University of Leicester'], 'affiliations': [{'raw_affiliation_string': 'University of Leicester', 'institution_ids': ['https://openalex.org/I153648349']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040062593', 'display_name': 'Luís M. Ruilope', 'orcid': 'https://orcid.org/0000-0001-6278-7951'}, 'institutions': [{'id': 'https://openalex.org/I121748325', 'display_name': 'Universidad Complutense de Madrid', 'ror': 'https://ror.org/02p0gd045', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I121748325']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Luis Miguel Ruilope', 'raw_affiliation_strings': ['Complutense University#TAB#'], 'affiliations': [{'raw_affiliation_string': 'Complutense University#TAB#', 'institution_ids': ['https://openalex.org/I121748325']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111429189', 'display_name': 'Gordon T. McInnes', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I7882870', 'display_name': 'University of Glasgow', 'ror': 'https://ror.org/00vtgdb53', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I7882870']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Gordon T McInnes', 'raw_affiliation_strings': ['University of Glasgow'], 'affiliations': [{'raw_affiliation_string': 'University of Glasgow', 'institution_ids': ['https://openalex.org/I7882870']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108629906', 'display_name': 'John Connell', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I177639307', 'display_name': 'University of Dundee', 'ror': 'https://ror.org/03h2bxq36', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I177639307']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'John M Connell', 'raw_affiliation_strings': ['University of Dundee'], 'affiliations': [{'raw_affiliation_string': 'University of Dundee', 'institution_ids': ['https://openalex.org/I177639307']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5072989992', 'display_name': 'Thomas M. MacDonald', 'orcid': 'https://orcid.org/0000-0001-5189-6669'}, 'institutions': [{'id': 'https://openalex.org/I177639307', 'display_name': 'University of Dundee', 'ror': 'https://ror.org/03h2bxq36', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I177639307']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Thomas M MacDonald', 'raw_affiliation_strings': ['University of Dundee'], 'affiliations': [{'raw_affiliation_string': 'University of Dundee', 'institution_ids': ['https://openalex.org/I177639307']}]}], 'institution_assertions': [], 'countries_distinct_count': 5, 'institutions_distinct_count': 8, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 15.806, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 242, 'citation_normalized_percentile': {'value': 0.999911, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '29', 'issue': '5', 'first_page': '980', 'last_page': '990'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11839', 'display_name': 'Hormonal Regulation and Hypertension', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11839', 'display_name': 'Hormonal Regulation and Hypertension', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10144', 'display_name': 'Blood Pressure and Hypertension Studies', 'score': 0.9967, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11054', 'display_name': 'Adrenal and Paraganglionic Tumors', 'score': 0.9923, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/eplerenone', 'display_name': 'Eplerenone', 'score': 0.9857009}, {'id': 'https://openalex.org/keywords/primary-aldosteronism', 'display_name': 'Primary Aldosteronism', 'score': 0.8055638}, {'id': 'https://openalex.org/keywords/tolerability', 'display_name': 'Tolerability', 'score': 0.64581805}, {'id': 'https://openalex.org/keywords/essential-hypertension', 'display_name': 'Essential hypertension', 'score': 0.50140643}, {'id': 'https://openalex.org/keywords/hyperaldosteronism', 'display_name': 'Hyperaldosteronism', 'score': 0.43805122}], 'concepts': [{'id': 'https://openalex.org/C2780072264', 'wikidata': 'https://www.wikidata.org/wiki/Q423804', 'display_name': 'Eplerenone', 'level': 4, 'score': 0.9857009}, {'id': 'https://openalex.org/C2776379505', 'wikidata': 'https://www.wikidata.org/wiki/Q422188', 'display_name': 'Spironolactone', 'level': 3, 'score': 0.94386184}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8619653}, {'id': 'https://openalex.org/C2780233176', 'wikidata': 'https://www.wikidata.org/wiki/Q1939330', 'display_name': 'Primary aldosteronism', 'level': 3, 'score': 0.8055638}, {'id': 'https://openalex.org/C2778375690', 'wikidata': 'https://www.wikidata.org/wiki/Q7814214', 'display_name': 'Tolerability', 'level': 3, 'score': 0.64581805}, {'id': 'https://openalex.org/C189135053', 'wikidata': 'https://www.wikidata.org/wiki/Q3454531', 'display_name': 'Mineralocorticoid receptor', 'level': 3, 'score': 0.61565036}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.5743239}, {'id': 'https://openalex.org/C126894567', 'wikidata': 'https://www.wikidata.org/wiki/Q105650', 'display_name': 'Urology', 'level': 1, 'score': 0.5141526}, {'id': 'https://openalex.org/C2777097880', 'wikidata': 'https://www.wikidata.org/wiki/Q988405', 'display_name': 'Essential hypertension', 'level': 3, 'score': 0.50140643}, {'id': 'https://openalex.org/C2778525890', 'wikidata': 'https://www.wikidata.org/wiki/Q184564', 'display_name': 'Aldosterone', 'level': 2, 'score': 0.4863687}, {'id': 'https://openalex.org/C27081682', 'wikidata': 'https://www.wikidata.org/wiki/Q269829', 'display_name': 'Placebo', 'level': 3, 'score': 0.4389057}, {'id': 'https://openalex.org/C2776292634', 'wikidata': 'https://www.wikidata.org/wiki/Q1640860', 'display_name': 'Hyperaldosteronism', 'level': 3, 'score': 0.43805122}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.41778755}, {'id': 'https://openalex.org/C197934379', 'wikidata': 'https://www.wikidata.org/wiki/Q2047938', 'display_name': 'Adverse effect', 'level': 2, 'score': 0.38382173}, {'id': 'https://openalex.org/C84393581', 'wikidata': 'https://www.wikidata.org/wiki/Q82642', 'display_name': 'Blood pressure', 'level': 2, 'score': 0.18061984}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.047542036}, {'id': 'https://openalex.org/C204787440', 'wikidata': 'https://www.wikidata.org/wiki/Q188504', 'display_name': 'Alternative medicine', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000959', 'descriptor_name': 'Antihypertensive Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D006929', 'descriptor_name': 'Hyperaldosteronism', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D013148', 'descriptor_name': 'Spironolactone', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D013148', 'descriptor_name': 'Spironolactone', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000959', 'descriptor_name': 'Antihypertensive Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004311', 'descriptor_name': 'Double-Blind Method', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077545', 'descriptor_name': 'Eplerenone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006929', 'descriptor_name': 'Hyperaldosteronism', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010919', 'descriptor_name': 'Placebos', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011788', 'descriptor_name': 'Quality of Life', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013148', 'descriptor_name': 'Spironolactone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/hjh.0b013e3283455ca5', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S115964404', 'display_name': 'Journal of Hypertension', 'issn_l': '0263-6352', 'issn': ['0263-6352', '1473-5598'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21451421', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.74, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 35, 'referenced_works': ['https://openalex.org/W122460778', 'https://openalex.org/W1971136179', 'https://openalex.org/W1976396826', 'https://openalex.org/W1977014222', 'https://openalex.org/W1977973738', 'https://openalex.org/W1980094514', 'https://openalex.org/W1998359135', 'https://openalex.org/W2017946023', 'https://openalex.org/W2019439141', 'https://openalex.org/W2029841082', 'https://openalex.org/W2032582841', 'https://openalex.org/W2047908219', 'https://openalex.org/W2058801122', 'https://openalex.org/W2061764902', 'https://openalex.org/W2062266308', 'https://openalex.org/W2064532153', 'https://openalex.org/W2078741210', 'https://openalex.org/W2086969647', 'https://openalex.org/W2089068749', 'https://openalex.org/W2098519186', 'https://openalex.org/W2099370101', 'https://openalex.org/W2107999636', 'https://openalex.org/W2116965552', 'https://openalex.org/W2118987197', 'https://openalex.org/W2119620107', 'https://openalex.org/W2125226019', 'https://openalex.org/W2135100154', 'https://openalex.org/W2152094259', 'https://openalex.org/W2156903075', 'https://openalex.org/W2162569186', 'https://openalex.org/W2323458614', 'https://openalex.org/W2414167269', 'https://openalex.org/W3022929210', 'https://openalex.org/W3140102005', 'https://openalex.org/W4296588245'], 'related_works': ['https://openalex.org/W4232964041', 'https://openalex.org/W2964465537', 'https://openalex.org/W2801040858', 'https://openalex.org/W2320541894', 'https://openalex.org/W2279875401', 'https://openalex.org/W2189187458', 'https://openalex.org/W2130764257', 'https://openalex.org/W2009328678', 'https://openalex.org/W1817639972', 'https://openalex.org/W1598280036'], 'abstract_inverted_index': {'Background': [0], 'Eplerenone': [1], 'is': [2], 'claimed': [3], 'to': [4, 64, 91, 130, 194], 'be': [5, 87], 'a': [6, 54, 65, 83, 100], 'more': [7, 191], 'selective': [8], 'blocker': [9], 'of': [10, 29, 70, 126, 133, 188, 218, 225], 'the': [11, 24, 123, 136, 185], 'mineralocorticoid': [12], 'receptor': [13], 'than': [14, 109, 115, 159, 223], 'spironolactone': [15, 32, 71, 129, 160, 183, 195, 219], 'being': [16], 'associated': [17, 37, 229], 'with': [18, 35, 38, 230], 'fewer': [19], 'antiandrogenic': [20], 'side-effects.': [21], 'We': [22], 'compared': [23], 'efficacy,': [25], 'safety': [26], 'and': [27, 49, 98, 107, 112, 182, 205], 'tolerability': [28], 'eplerenone': [30, 77, 127, 134, 153, 181, 226], 'versus': [31, 128, 200, 209], 'in': [33, 135, 141, 148, 184, 227], 'patients': [34, 59, 89, 192], 'hypertension': [36, 228], 'primary': [39, 96, 119, 231], 'aldosteronism.': [40, 232], 'Methods': [41], 'The': [42, 118, 215], 'study': [43], 'was': [44, 122, 220], 'multicentre,': [45], 'randomized,': [46, 88], 'double-blind,': [47, 67], 'active-controlled,': [48], 'parallel': [50], 'group': [51], 'design.': [52, 85], 'Following': [53], 'single-blind,': [55], 'placebo': [56], 'run-in': [57], 'period,': [58], 'were': [60, 150, 176], 'randomized': [61, 193], '1:': [62], '1': [63], '16-week': [66], 'treatment': [68], 'period': [69], '(75–225': [72], 'mg': [73, 79], 'once': [74, 80], 'daily)': [75, 81], 'or': [76], '(100–300': [78], 'using': [82], 'titration-to-effect': [84], 'To': [86], 'had': [90], 'meet': [92], 'biochemical': [93], 'criteria': [94], 'for': [95], 'aldosteronism': [97], 'have': [99], 'seated': [101, 142], 'DBP': [102, 149], 'at': [103], 'least': [104], '90': [105], 'mmHg': [106, 111, 168], 'less': [108, 114, 151], '120': [110], 'SBP': [113], '200': [116], 'mmHg.': [117], 'efficacy': [120], 'endpoint': [121], 'antihypertensive': [124, 216], 'effect': [125, 217], 'establish': [131], 'noninferiority': [132], 'mean': [137], 'change': [138], 'from': [139, 146], 'baseline': [140, 147], 'DBP.': [143], 'Results': [144], 'Changes': [145], 'on': [152], '(−5.6': [154], '±': [155, 162], '1.3': [156, 163], 'SE': [157, 164], 'mmHg)': [158, 165], '(−12.5': [161], '[difference,': [166], '−6.9': [167], '(−10.6,': [169], '−3.3);': [170], 'P': [171, 202, 211], '<': [172], '0.001].': [173], 'Although': [174], 'there': [175], 'no': [177], 'significant': [178], 'differences': [179], 'between': [180], 'overall': [186], 'incidence': [187], 'adverse': [189], 'events,': [190], 'developed': [196], 'male': [197], 'gynaecomastia': [198], '(21.2': [199], '4.5%;': [201], '=': [203, 212], '0.033)': [204], 'female': [206], 'mastodynia': [207], '(21.1': [208], '0.0%;': [210], '0.026).': [213], 'Conclusion': [214], 'significantly': [221], 'greater': [222], 'that': [224]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1977186839', 'counts_by_year': [{'year': 2024, 'cited_by_count': 12}, {'year': 2023, 'cited_by_count': 23}, {'year': 2022, 'cited_by_count': 18}, {'year': 2021, 'cited_by_count': 17}, {'year': 2020, 'cited_by_count': 11}, {'year': 2019, 'cited_by_count': 12}, {'year': 2018, 'cited_by_count': 13}, {'year': 2017, 'cited_by_count': 15}, {'year': 2016, 'cited_by_count': 19}, {'year': 2015, 'cited_by_count': 30}, {'year': 2014, 'cited_by_count': 22}, {'year': 2013, 'cited_by_count': 18}, {'year': 2012, 'cited_by_count': 24}], 'updated_date': '2024-12-15T13:16:34.944173', 'created_date': '2016-06-24'}