Title: Appraisal of calcium oxalate solubility In sodium chloride and sodium-calcium chloride solutions
Abstract: Critical examination of existing calcium oxalate (CaC204) solubility data revealed that the prevailing concept of calcium oxalate solubility is inconsistent with experimental results. Studies designed to give a thermodynamic description of calcium oxalate solubility indicate that (1) the stability of the calcium oxalate complex is lower than has previously been reported by more than 50 per cent (this is the first report of a measurement of the stability of the complex at 38°C.); (2) the formation of dicalcium oxalate (Ca2C2042+) complex causes substantial amounts of calcium oxalate to be solubilized at the calcium concentrations found in urine; and (3) a monosodium oxalate (NaC204−) complex can also form, but is present in urine in only small amounts. The formation of dicalcium oxalate complex makes calcium oxalate solubility in urine somewhat insensitive to calcium concentration over the physiologic range. Manipulation of urinary calcium is thus expected to have little effect on the progress of oxalate urolithiasis.
Publication Year: 1973
Publication Date: 1973-02-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 16
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