Title: 800-4 Coronary Calcification by Ultrafast Computed Tomography is an Independent Predictor of Obstructive Coronary Artery Disease: A Multivariate Risk Factor Analysis
Abstract: Coronary calcification (CC) as detected by ultrafast computed tomography (UFCT) is associated with obstructive coronary artery disease. We compared CC to cardiac risk factors as independent predictors of angiographically significant coronary artery disease (CAD). Cardiac risk factors were obtained in 263 patients which included age, gender, family history of CAD in a first degree relative, hypercholesterolemia, hypertension, tobacco use, and diabetes mellitus. All 263 patients underwent UFCT coronary scanning as well as coronary angiography within three months. Coronary calcification score was derived using Agatston's method and obstructive CAD was defined as greater than 50% luminal diameter stenosis in 1 or more coronary vessels. Using chi square analysis, male gender, hypercholesterolemia, coronary calcium score, and age were all found to be statistically significant predictors of obstructive CAD. However, the strongest predictor of obstructive CAD was coronary calcium score (p < 0.00001). Hypertension and tobacco use were not predictive. Multivariate logistical regression was also employed which revealed significant associations between obstructive CAD and coronary calcium score, age, male gender, and hypercholesterolemia. Coronary calcium score determined by UFCT, when compared to all other risk factors, is the most predictive factor of obstructive CAD.
Publication Year: 1995
Publication Date: 1995-02-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 1
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