Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1975578482', 'doi': 'https://doi.org/10.1248/bpb.26.988', 'title': 'Influence of Liver Disease on Phenolsulfonphthalein Absorption from Liver Surface to Examine Possibility of Direct Liver Surface Application for Drug Targeting', 'display_name': 'Influence of Liver Disease on Phenolsulfonphthalein Absorption from Liver Surface to Examine Possibility of Direct Liver Surface Application for Drug Targeting', 'publication_year': 2003, 'publication_date': '2003-01-01', 'ids': {'openalex': 'https://openalex.org/W1975578482', 'doi': 'https://doi.org/10.1248/bpb.26.988', 'mag': '1975578482', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12843624'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1248/bpb.26.988', 'pdf_url': 'https://www.jstage.jst.go.jp/article/bpb/26/7/26_7_988/_pdf', 'source': {'id': 'https://openalex.org/S165235614', 'display_name': 'Biological and Pharmaceutical Bulletin', 'issn_l': '0918-6158', 'issn': ['0918-6158', '1347-5215'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310313382', 'host_organization_name': 'Pharmaceutical Society of Japan', 'host_organization_lineage': ['https://openalex.org/P4310313382'], 'host_organization_lineage_names': ['Pharmaceutical Society of Japan'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.jstage.jst.go.jp/article/bpb/26/7/26_7_988/_pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5061258543', 'display_name': 'Koyo Nishida', 'orcid': 'https://orcid.org/0000-0003-4714-0978'}, 'institutions': [{'id': 'https://openalex.org/I43777268', 'display_name': 'Nagasaki University', 'ror': 'https://ror.org/058h74p94', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I43777268']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Koyo Nishida', 'raw_affiliation_strings': ['Department of Clinical Pharmacy, Graduate School of Biomedical Sciences, Nagasaki University'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Pharmacy, Graduate School of Biomedical Sciences, Nagasaki University', 'institution_ids': ['https://openalex.org/I43777268']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036501583', 'display_name': 'Tominori Honda', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I43777268', 'display_name': 'Nagasaki University', 'ror': 'https://ror.org/058h74p94', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I43777268']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tominori Honda', 'raw_affiliation_strings': ['Department of Clinical Pharmacy, Graduate School of Biomedical Sciences, Nagasaki University'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Pharmacy, Graduate School of Biomedical Sciences, Nagasaki University', 'institution_ids': ['https://openalex.org/I43777268']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102363479', 'display_name': 'Mikiro Nakashima', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I43777268', 'display_name': 'Nagasaki University', 'ror': 'https://ror.org/058h74p94', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I43777268']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Mikiro Nakashima', 'raw_affiliation_strings': ['Department of Hospital Pharmacy, Nagasaki University School of Medicine.'], 'affiliations': [{'raw_affiliation_string': 'Department of Hospital Pharmacy, Nagasaki University School of Medicine.', 'institution_ids': ['https://openalex.org/I43777268']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110001027', 'display_name': 'Hitoshi Sasaki', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I43777268', 'display_name': 'Nagasaki University', 'ror': 'https://ror.org/058h74p94', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I43777268']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hitoshi Sasaki', 'raw_affiliation_strings': ['Department of Hospital Pharmacy, Nagasaki University School of Medicine.'], 'affiliations': [{'raw_affiliation_string': 'Department of Hospital Pharmacy, Nagasaki University School of Medicine.', 'institution_ids': ['https://openalex.org/I43777268']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5110061423', 'display_name': 'Junzo Nakamura', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I43777268', 'display_name': 'Nagasaki University', 'ror': 'https://ror.org/058h74p94', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I43777268']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Junzo Nakamura', 'raw_affiliation_strings': ['Department of Clinical Pharmacy, Graduate School of Biomedical Sciences, Nagasaki University'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Pharmacy, Graduate School of Biomedical Sciences, Nagasaki University', 'institution_ids': ['https://openalex.org/I43777268']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.943, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 8, 'citation_normalized_percentile': {'value': 0.745509, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 78, 'max': 79}, 'biblio': {'volume': '26', 'issue': '7', 'first_page': '988', 'last_page': '993'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11465', 'display_name': 'Drug-Induced Hepatotoxicity and Protection', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11465', 'display_name': 'Drug-Induced Hepatotoxicity and Protection', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10570', 'display_name': 'Drug Transport and Resistance Mechanisms', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10351', 'display_name': 'Liver Disease Diagnosis and Treatment', 'score': 0.997, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/liver-disease', 'display_name': 'Liver disease', 'score': 0.60217994}], 'concepts': [{'id': 'https://openalex.org/C2777359374', 'wikidata': 'https://www.wikidata.org/wiki/Q225045', 'display_name': 'Carbon tetrachloride', 'level': 2, 'score': 0.7114154}, {'id': 'https://openalex.org/C2780035454', 'wikidata': 'https://www.wikidata.org/wiki/Q8386', 'display_name': 'Drug', 'level': 2, 'score': 0.6081864}, {'id': 'https://openalex.org/C125287762', 'wikidata': 'https://www.wikidata.org/wiki/Q1758948', 'display_name': 'Absorption (acoustics)', 'level': 2, 'score': 0.60274315}, {'id': 'https://openalex.org/C2777075537', 'wikidata': 'https://www.wikidata.org/wiki/Q929737', 'display_name': 'Liver disease', 'level': 2, 'score': 0.60217994}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5872193}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.4673059}, {'id': 'https://openalex.org/C112705442', 'wikidata': 'https://www.wikidata.org/wiki/Q323936', 'display_name': 'Pharmacokinetics', 'level': 2, 'score': 0.42155275}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.39771956}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.30128616}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.20298573}, {'id': 'https://openalex.org/C192562407', 'wikidata': 'https://www.wikidata.org/wiki/Q228736', 'display_name': 'Materials science', 'level': 0, 'score': 0.13334158}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.06872931}, {'id': 'https://openalex.org/C159985019', 'wikidata': 'https://www.wikidata.org/wiki/Q181790', 'display_name': 'Composite material', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D016503', 'descriptor_name': 'Drug Delivery Systems', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008107', 'descriptor_name': 'Liver Diseases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D010637', 'descriptor_name': 'Phenolsulfonphthalein', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': True}, {'descriptor_ui': 'D010637', 'descriptor_name': 'Phenolsulfonphthalein', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D000042', 'descriptor_name': 'Absorption', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000042', 'descriptor_name': 'Absorption', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D000042', 'descriptor_name': 'Absorption', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002252', 'descriptor_name': 'Carbon Tetrachloride Poisoning', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002252', 'descriptor_name': 'Carbon Tetrachloride Poisoning', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056486', 'descriptor_name': 'Chemical and Drug Induced Liver Injury', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016503', 'descriptor_name': 'Drug Delivery Systems', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D066298', 'descriptor_name': 'In Vitro Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008107', 'descriptor_name': 'Liver Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010637', 'descriptor_name': 'Phenolsulfonphthalein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017208', 'descriptor_name': 'Rats, Wistar', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1248/bpb.26.988', 'pdf_url': 'https://www.jstage.jst.go.jp/article/bpb/26/7/26_7_988/_pdf', 'source': {'id': 'https://openalex.org/S165235614', 'display_name': 'Biological and Pharmaceutical Bulletin', 'issn_l': '0918-6158', 'issn': ['0918-6158', '1347-5215'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310313382', 'host_organization_name': 'Pharmaceutical Society of Japan', 'host_organization_lineage': ['https://openalex.org/P4310313382'], 'host_organization_lineage_names': ['Pharmaceutical Society of Japan'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/10069/8384', 'pdf_url': 'https://nagasaki-u.repo.nii.ac.jp/record/23169/files/BPBul26_988.pdf', 'source': {'id': 'https://openalex.org/S4306400113', 'display_name': "Nagasaki University's Academic Output SITE (Nagasaki University)", 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I43777268', 'host_organization_name': 'Nagasaki University', 'host_organization_lineage': ['https://openalex.org/I43777268'], 'host_organization_lineage_names': ['Nagasaki University'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/10069/6680', 'pdf_url': 'https://nagasaki-u.repo.nii.ac.jp/record/23374/files/BPBul26_988.pdf', 'source': {'id': 'https://openalex.org/S4306400113', 'display_name': "Nagasaki University's Academic Output SITE (Nagasaki University)", 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I43777268', 'host_organization_name': 'Nagasaki University', 'host_organization_lineage': ['https://openalex.org/I43777268'], 'host_organization_lineage_names': ['Nagasaki University'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12843624', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1248/bpb.26.988', 'pdf_url': 'https://www.jstage.jst.go.jp/article/bpb/26/7/26_7_988/_pdf', 'source': {'id': 'https://openalex.org/S165235614', 'display_name': 'Biological and Pharmaceutical Bulletin', 'issn_l': '0918-6158', 'issn': ['0918-6158', '1347-5215'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310313382', 'host_organization_name': 'Pharmaceutical Society of Japan', 'host_organization_lineage': ['https://openalex.org/P4310313382'], 'host_organization_lineage_names': ['Pharmaceutical Society of Japan'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.82, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 27, 'referenced_works': ['https://openalex.org/W18157314', 'https://openalex.org/W182382073', 'https://openalex.org/W1968628281', 'https://openalex.org/W1973887423', 'https://openalex.org/W1978155760', 'https://openalex.org/W1980034261', 'https://openalex.org/W1999785096', 'https://openalex.org/W2004255132', 'https://openalex.org/W2007580975', 'https://openalex.org/W2012666029', 'https://openalex.org/W2052755604', 'https://openalex.org/W2057312851', 'https://openalex.org/W2057785105', 'https://openalex.org/W2059545303', 'https://openalex.org/W2085921508', 'https://openalex.org/W2087526401', 'https://openalex.org/W2091812113', 'https://openalex.org/W2094137249', 'https://openalex.org/W2098015264', 'https://openalex.org/W2103082009', 'https://openalex.org/W2106996524', 'https://openalex.org/W2162553170', 'https://openalex.org/W2224010948', 'https://openalex.org/W2313990166', 'https://openalex.org/W2317227650', 'https://openalex.org/W2323082721', 'https://openalex.org/W2485546735'], 'related_works': ['https://openalex.org/W3203569471', 'https://openalex.org/W3003702269', 'https://openalex.org/W2412506692', 'https://openalex.org/W2390434404', 'https://openalex.org/W2385764600', 'https://openalex.org/W2352261954', 'https://openalex.org/W2174503459', 'https://openalex.org/W2104694836', 'https://openalex.org/W2094370239', 'https://openalex.org/W1964707752'], 'abstract_inverted_index': {'We': [0, 48], 'have': [1], 'examined': [2, 65], 'the': [3, 12, 18, 25, 36, 60, 72, 82, 101, 109, 115, 121, 140, 151, 155, 168, 181, 196, 201, 209, 213, 225, 234, 238, 265, 269], 'influence': [4], 'of': [5, 30, 38, 87, 143, 178, 222, 240, 250], 'liver': [6, 13, 40, 61, 73, 102, 144, 152, 182, 210, 251, 270, 274, 285], 'disease': [7, 62, 275], 'on': [8], 'drug': [9, 22, 45, 66, 206, 245], 'absorption': [10, 67, 116, 127, 149, 173, 246, 266], 'from': [11, 100, 150, 167, 180, 268], 'surface': [14, 41, 103, 145, 153, 211, 271], 'membrane,': [15], 'regarded': [16], 'as': [17, 43, 59, 95, 247], 'first': [19], 'barrier': [20], 'for': [21, 139, 284], 'targeting': [23, 46], 'to': [24, 34, 71, 108, 160, 200, 208, 216, 279], 'liver.': [26], 'The': [27, 147, 171, 220], 'main': [28], 'purpose': [29], 'this': [31, 281], 'study': [32], 'is': [33, 255], 'examine': [35], 'possibility': [37], 'direct': [39], 'application': [42, 70, 207], 'a': [44, 77, 88, 96, 186, 248, 273], 'method.': [47], 'employed': [49], 'rats': [50, 111], 'intoxicated': [51], 'with': [52], 'carbon': [53], 'tetrachloride': [54], '(CCl4)': [55], 'or': [56], 'D-galactosamine': [57], '(GAL)': [58], 'model,': [63], 'and': [64, 189], 'characteristics': [68], 'after': [69], 'surface,': [74, 183], 'by': [75, 164, 185], 'utilizing': [76], 'cylindrical': [78], 'diffusion': [79, 169], 'cell.': [80, 170], 'In': [81], 'liver-intoxicated': [83], 'rats,': [84], 'about': [85, 229], '90%': [86], 'low': [89], 'molecular': [90], 'weight': [91], 'drug,': [92], 'phenolsulfonphthalein': [93], '(PSP),': [94], 'model': [97, 188], 'was': [98, 118, 128, 158, 228], 'absorbed': [99], 'in': [104, 120, 130, 154, 195, 212, 224, 233, 243, 264, 272], '6': [105], 'h,': [106], 'similar': [107], 'normal': [110, 235], '(no': [112], 'treatment).': [113], 'Although': [114], 'rate': [117, 174, 267], 'increased': [119, 193], 'CCl4': [122, 156, 197, 226], 'group,': [123, 132, 236], 'whereas': [124], 'slightly': [125], 'retarded': [126], 'observed': [129], 'GAL': [131], 'there': [133, 258], 'should': [134], 'be': [135, 260], 'no': [136, 261], 'serious': [137], 'problem': [138], 'clinical': [141, 218], 'use': [142], 'application.': [146], 'PSP': [148, 179, 223], 'group': [157, 198, 227], 'indicated': [159], 'obey': [161], 'first-order': [162, 172], 'kinetics': [163], 'elimination': [165, 190], 'profile': [166], 'constant': [175], 'Ka': [176, 221], 'values': [177], 'obtained': [184], 'compartment': [187], 'profile,': [191], 'were': [192], '1.3-fold': [194], 'compared': [199], 'control.': [202], 'Moreover,': [203], 'we': [204], 'performed': [205], 'peritoneal': [214, 244], 'cavity': [215], 'assume': [217], 'use.': [219], '4-fold': [230], 'larger': [231], 'than': [232], 'implying': [237], 'importance': [239], 'estimating': [241], 'changes': [242], 'result': [249], 'disease.': [252], 'Consequently,': [253], 'it': [254], 'expected': [256], 'that': [257], 'will': [259], 'marked': [262], 'decline': [263], 'state,': [276], 'leading': [277], 'us': [278], 'apply': [280], 'administration': [282], 'method': [283], 'targeting.': [286]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1975578482', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}], 'updated_date': '2024-12-13T18:38:39.849072', 'created_date': '2016-06-24'}