Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1975319833', 'doi': 'https://doi.org/10.1016/s0167-5273(02)00421-7', 'title': 'Coronary and systemic hemodynamic effects of sildenafil citrate: from basic science to clinical studies in patients with cardiovascular disease', 'display_name': 'Coronary and systemic hemodynamic effects of sildenafil citrate: from basic science to clinical studies in patients with cardiovascular disease', 'publication_year': 2002, 'publication_date': '2002-12-01', 'ids': {'openalex': 'https://openalex.org/W1975319833', 'doi': 'https://doi.org/10.1016/s0167-5273(02)00421-7', 'mag': '1975319833', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12419549'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0167-5273(02)00421-7', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S13342628', 'display_name': 'International Journal of Cardiology', 'issn_l': '0167-5273', 'issn': ['0167-5273', '1874-1754'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5034366220', 'display_name': 'Hunter Gillies', 'orcid': 'https://orcid.org/0009-0003-6677-7445'}, 'institutions': [{'id': 'https://openalex.org/I180857899', 'display_name': 'Pfizer (United States)', 'ror': 'https://ror.org/01xdqrp08', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I180857899']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hunter C Gillies', 'raw_affiliation_strings': ['Clinical Development, Pfizer Global Research and Development, Ramsgate Road, Kent CT13 9NJ, Sandwich, UK.'], 'affiliations': [{'raw_affiliation_string': 'Clinical Development, Pfizer Global Research and Development, Ramsgate Road, Kent CT13 9NJ, Sandwich, UK.', 'institution_ids': ['https://openalex.org/I180857899']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046012874', 'display_name': 'David Roblin', 'orcid': 'https://orcid.org/0000-0003-1106-8062'}, 'institutions': [{'id': 'https://openalex.org/I189718659', 'display_name': 'Pfizer (United Kingdom)', 'ror': 'https://ror.org/04x4v8p40', 'country_code': 'GB', 'type': 'company', 'lineage': ['https://openalex.org/I180857899', 'https://openalex.org/I189718659']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'David Roblin', 'raw_affiliation_strings': ['Clinical Development, Pfizer Global Research and Development, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK'], 'affiliations': [{'raw_affiliation_string': 'Clinical Development, Pfizer Global Research and Development, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK', 'institution_ids': ['https://openalex.org/I189718659']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5060925457', 'display_name': 'Graham Jackson', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I189718659', 'display_name': 'Pfizer (United Kingdom)', 'ror': 'https://ror.org/04x4v8p40', 'country_code': 'GB', 'type': 'company', 'lineage': ['https://openalex.org/I180857899', 'https://openalex.org/I189718659']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Graham Jackson', 'raw_affiliation_strings': ['Clinical Development, Pfizer Global Research and Development, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK'], 'affiliations': [{'raw_affiliation_string': 'Clinical Development, Pfizer Global Research and Development, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK', 'institution_ids': ['https://openalex.org/I189718659']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3340, 'currency': 'USD', 'value_usd': 3340, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.032, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 83, 'citation_normalized_percentile': {'value': 0.662301, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '86', 'issue': '2-3', 'first_page': '131', 'last_page': '141'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10459', 'display_name': 'Sexual function and dysfunction studies', 'score': 0.9962, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10459', 'display_name': 'Sexual function and dysfunction studies', 'score': 0.9962, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11146', 'display_name': 'Hormonal and reproductive studies', 'score': 0.9901, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10144', 'display_name': 'Blood Pressure and Hypertension Studies', 'score': 0.98, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cyclic-guanosine-monophosphate', 'display_name': 'Cyclic guanosine monophosphate', 'score': 0.74015284}, {'id': 'https://openalex.org/keywords/endothelial-dysfunction', 'display_name': 'Endothelial Dysfunction', 'score': 0.5276267}, {'id': 'https://openalex.org/keywords/phosphodiesterase-inhibitor', 'display_name': 'Phosphodiesterase inhibitor', 'score': 0.41725016}], 'concepts': [{'id': 'https://openalex.org/C2776768464', 'wikidata': 'https://www.wikidata.org/wiki/Q191521', 'display_name': 'Sildenafil', 'level': 2, 'score': 0.96774846}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.93265384}, {'id': 'https://openalex.org/C2780994212', 'wikidata': 'https://www.wikidata.org/wiki/Q422511', 'display_name': 'Cyclic guanosine monophosphate', 'level': 3, 'score': 0.74015284}, {'id': 'https://openalex.org/C2779929075', 'wikidata': 'https://www.wikidata.org/wiki/Q184674', 'display_name': 'Erectile dysfunction', 'level': 2, 'score': 0.73496175}, {'id': 'https://openalex.org/C74534348', 'wikidata': 'https://www.wikidata.org/wiki/Q410798', 'display_name': 'cGMP-specific phosphodiesterase type 5', 'level': 3, 'score': 0.70974284}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.613737}, {'id': 'https://openalex.org/C164705383', 'wikidata': 'https://www.wikidata.org/wiki/Q10379', 'display_name': 'Cardiology', 'level': 1, 'score': 0.59062284}, {'id': 'https://openalex.org/C2780972559', 'wikidata': 'https://www.wikidata.org/wiki/Q550061', 'display_name': 'Endothelial dysfunction', 'level': 2, 'score': 0.5276267}, {'id': 'https://openalex.org/C58245268', 'wikidata': 'https://www.wikidata.org/wiki/Q456026', 'display_name': 'Vascular resistance', 'level': 3, 'score': 0.49586067}, {'id': 'https://openalex.org/C2780074459', 'wikidata': 'https://www.wikidata.org/wiki/Q389735', 'display_name': 'Heart disease', 'level': 2, 'score': 0.49347508}, {'id': 'https://openalex.org/C120770815', 'wikidata': 'https://www.wikidata.org/wiki/Q14859627', 'display_name': 'Vasodilation', 'level': 2, 'score': 0.44585186}, {'id': 'https://openalex.org/C2780930700', 'wikidata': 'https://www.wikidata.org/wiki/Q1128595', 'display_name': 'Pulmonary hypertension', 'level': 2, 'score': 0.4413297}, {'id': 'https://openalex.org/C2778198053', 'wikidata': 'https://www.wikidata.org/wiki/Q181754', 'display_name': 'Heart failure', 'level': 2, 'score': 0.43021515}, {'id': 'https://openalex.org/C178853913', 'wikidata': 'https://www.wikidata.org/wiki/Q1642137', 'display_name': 'Hemodynamics', 'level': 2, 'score': 0.42026335}, {'id': 'https://openalex.org/C2776766087', 'wikidata': 'https://www.wikidata.org/wiki/Q418251', 'display_name': 'Phosphodiesterase inhibitor', 'level': 2, 'score': 0.41725016}, {'id': 'https://openalex.org/C519581460', 'wikidata': 'https://www.wikidata.org/wiki/Q207843', 'display_name': 'Nitric oxide', 'level': 2, 'score': 0.38919598}], 'mesh': [{'descriptor_ui': 'D002318', 'descriptor_name': 'Cardiovascular Diseases', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D006321', 'descriptor_name': 'Heart', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D006439', 'descriptor_name': 'Hemodynamics', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D010879', 'descriptor_name': 'Piperazines', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D010879', 'descriptor_name': 'Piperazines', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D014665', 'descriptor_name': 'Vasodilator Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D014665', 'descriptor_name': 'Vasodilator Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D002318', 'descriptor_name': 'Cardiovascular Diseases', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D002318', 'descriptor_name': 'Cardiovascular Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006321', 'descriptor_name': 'Heart', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006321', 'descriptor_name': 'Heart', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D006439', 'descriptor_name': 'Hemodynamics', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D006439', 'descriptor_name': 'Hemodynamics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010879', 'descriptor_name': 'Piperazines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011687', 'descriptor_name': 'Purines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000068677', 'descriptor_name': 'Sildenafil Citrate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013450', 'descriptor_name': 'Sulfones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014665', 'descriptor_name': 'Vasodilator Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0167-5273(02)00421-7', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S13342628', 'display_name': 'International Journal of Cardiology', 'issn_l': '0167-5273', 'issn': ['0167-5273', '1874-1754'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12419549', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.83, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 44, 'referenced_works': ['https://openalex.org/W1496325698', 'https://openalex.org/W1927450934', 'https://openalex.org/W1971406218', 'https://openalex.org/W1972469636', 'https://openalex.org/W1976024273', 'https://openalex.org/W1981902060', 'https://openalex.org/W1982642084', 'https://openalex.org/W1984435538', 'https://openalex.org/W1985431943', 'https://openalex.org/W1994749562', 'https://openalex.org/W1997538832', 'https://openalex.org/W1998143238', 'https://openalex.org/W2009879610', 'https://openalex.org/W2010124072', 'https://openalex.org/W2026318378', 'https://openalex.org/W2027202120', 'https://openalex.org/W2027457721', 'https://openalex.org/W2031197996', 'https://openalex.org/W2036872791', 'https://openalex.org/W2057116025', 'https://openalex.org/W2062678616', 'https://openalex.org/W2067833505', 'https://openalex.org/W2068239827', 'https://openalex.org/W2077739986', 'https://openalex.org/W2082266361', 'https://openalex.org/W2087576623', 'https://openalex.org/W2095820279', 'https://openalex.org/W2097450392', 'https://openalex.org/W2121926246', 'https://openalex.org/W2143661166', 'https://openalex.org/W2149688277', 'https://openalex.org/W2168408827', 'https://openalex.org/W2170541055', 'https://openalex.org/W2317463698', 'https://openalex.org/W2320638340', 'https://openalex.org/W2323665635', 'https://openalex.org/W2328535822', 'https://openalex.org/W2336538695', 'https://openalex.org/W2338144962', 'https://openalex.org/W2406062456', 'https://openalex.org/W2408610080', 'https://openalex.org/W2412461385', 'https://openalex.org/W3148052688', 'https://openalex.org/W33566976'], 'related_works': ['https://openalex.org/W4389914260', 'https://openalex.org/W2806024343', 'https://openalex.org/W2651516585', 'https://openalex.org/W2427392931', 'https://openalex.org/W2409121387', 'https://openalex.org/W2133093303', 'https://openalex.org/W2063299927', 'https://openalex.org/W2028701630', 'https://openalex.org/W2020311830', 'https://openalex.org/W1879820078'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1975319833', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2025-01-05T20:37:45.074561', 'created_date': '2016-06-24'}