Publication Information

{'id': 'https://openalex.org/W1975166857', 'doi': 'https://doi.org/10.1001/jama.2012.5535', 'title': 'Effect of an Indwelling Pleural Catheter vs Chest Tube and Talc Pleurodesis for Relieving Dyspnea in Patients With Malignant Pleural Effusion', 'display_name': 'Effect of an Indwelling Pleural Catheter vs Chest Tube and Talc Pleurodesis for Relieving Dyspnea in Patients With Malignant Pleural Effusion', 'publication_year': 2012, 'publication_date': '2012-05-20', 'ids': {'openalex': 'https://openalex.org/W1975166857', 'doi': 'https://doi.org/10.1001/jama.2012.5535', 'mag': '1975166857', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22610520'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1001/jama.2012.5535', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S172573765', 'display_name': 'JAMA', 'issn_l': '0098-7484', 'issn': ['0098-7484', '1538-3598'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320259', 'host_organization_name': 'American Medical Association', 'host_organization_lineage': ['https://openalex.org/P4310320259'], 'host_organization_lineage_names': ['American Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5086761550', 'display_name': 'Helen Davies', 'orcid': 'https://orcid.org/0000-0001-6102-256X'}, 'institutions': [{'id': 'https://openalex.org/I2800861664', 'display_name': 'University Hospital of Wales', 'ror': 'https://ror.org/04fgpet95', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1299209451', 'https://openalex.org/I2800861664', 'https://openalex.org/I4210144625']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Helen E. 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'abstract_inverted_index': {'<h3>Context</h3>Malignant': [0], 'pleural': [1, 32, 71, 105, 350, 401], 'effusion': [2, 72, 402], 'causes': [3], 'disabling': [4], 'dyspnea': [5, 149, 161, 206, 250], 'in': [6, 55, 190, 197, 210, 225, 249, 251, 262, 292, 337, 344, 356, 375, 386], 'patients': [7, 68, 83, 342, 374, 398], 'with': [8, 69, 193, 202, 229, 258, 296, 317, 353, 399], 'a': [9, 103, 180, 203, 230, 245, 259, 297, 318], 'short': [10], 'life': [11], 'expectancy.': [12], 'Palliation': [13], 'is': [14], 'achieved': [15], 'by': [16, 114], 'fluid': [17], 'drainage,': [18, 118], 'but': [19], 'the': [20, 155, 198, 211, 226, 252, 266, 270, 293, 314, 345, 357, 372, 376, 387], 'most': [21], 'effective': [22, 37], 'first-line': [23], 'method': [24], 'has': [25], 'not': [26, 75], 'been': [27], 'determined.<h3>Objective</h3>To': [28], 'determine': [29], 'whether': [30], 'indwelling': [31], 'catheters': [33, 106], '(IPCs)': [34], 'are': [35], 'more': [36], 'than': [38], 'chest': [39, 130], 'tube': [40, 131], 'and': [41, 62, 98, 120, 133, 162, 218, 269, 307, 403, 414], 'talc': [42, 63, 125, 134, 227, 271, 315, 346, 388, 415], 'slurry': [43, 136], 'pleurodesis': [44, 78, 416], '(talc)': [45], 'at': [46, 87, 255, 417], 'relieving': [47, 418], 'dyspnea.<h3>Design</h3>Unblinded': [48], 'randomized': [49], 'controlled': [50], 'trial': [51], '(Second': [52], 'Therapeutic': [53], 'Intervention': [54], 'Malignant': [56], 'Effusion': [57], 'Trial': [58], '[TIME2])': [59], 'comparing': [60], 'IPC': [61, 212, 253, 267, 294, 358], '(1:1)': [64], 'for': [65, 102, 129, 135, 186, 313], 'which': [66], '106': [67], 'malignant': [70, 400], 'who': [73, 84], 'had': [74], 'previously': [76], 'undergone': [77], 'were': [79, 85, 92, 99, 107, 127], 'recruited': [80], 'from': [81, 94], '143': [82], 'treated': [86], '7': [88, 383], 'UK': [89], 'hospitals.': [90], 'Patients': [91], 'screened': [93], 'April': [95], '2007-February': [96], '2011': [97], 'followed': [100, 113], 'up': [101], 'year.<h3>Intervention</h3>Indwelling': [104], 'inserted': [108], 'on': [109], 'an': [110], 'outpatient': [111], 'basis,': [112], 'initial': [115, 287], 'large': [116], 'volume': [117], 'education,': [119], 'subsequent': [121], 'home': [122], 'drainage.': [123], 'The': [124], 'group': [126, 213, 254, 268, 272, 295, 347, 359, 378, 389], 'admitted': [128], 'insertion': [132], 'pleurodesis.<h3>Main': [137], 'Outcome': [138], 'Measure</h3>Patients': [139], 'completed': [140], 'daily': [141], '100-mm': [142], 'line': [143], 'visual': [144], 'analog': [145], 'scale': [146], '(VAS)': [147], 'of': [148, 208, 232, 273, 286, 299, 320, 339, 371, 384], 'over': [150], '42': [151, 200], 'days': [152, 201, 301, 309, 322], 'after': [153], 'undergoing': [154], 'intervention': [156], '(0': [157], 'mm': [158, 164, 169, 220, 234, 275], 'represents': [159, 165, 170], 'no': [160, 194, 334, 404, 409], '100': [163], 'maximum': [166], 'dyspnea;': [167], '10': [168], 'minimum': [171], 'clinically': [172], 'significant': [173, 195, 247, 335, 410], 'difference).': [174], 'Mean': [175], 'difference': [176, 196, 231, 261, 319, 336, 411], 'was': [177, 244, 289, 333, 408], 'analyzed': [178], 'using': [179], 'mixed-effects': [181], 'linear': [182], 'regression': [183], 'model': [184], 'adjusted': [185], 'minimization': [187], 'variables.<h3>Results</h3>Dyspnea': [188], 'improved': [189], 'both': [191], 'groups,': [192], 'first': [199], 'mean': [204, 260], 'VAS': [205, 263], 'score': [207, 264], '24.7': [209], '(95%': [214, 221, 235, 276, 323], 'CI,': [215, 222, 236, 277, 324, 365, 393], '19.3-30.1': [216], 'mm)': [217, 224], '24.4': [219], '19.4-29.4': [223], 'group,': [228, 316], '0.16': [233], '−6.82': [237], 'to': [238, 279, 326], '7.15;': [239], 'P': [240, 282, 329, 367, 395], '=': [241, 283, 368, 396], '.96).': [242], 'There': [243, 332], 'statistically': [246], 'improvement': [248], '6': [256], 'months,': [257], 'between': [265, 412], '−14.0': [274], '−25.2': [278], '−2.8': [280], 'mm;': [281], '.01).': [284], 'Length': [285], 'hospitalization': [288], 'significantly': [290], 'shorter': [291], 'median': [298], '0': [300], '(interquartile': [302], 'range': [303], '[IQR],': [304], '0-1': [305], 'day)': [306], '4': [308], '(IQR,': [310], '2-6': [311], 'days)': [312], '−3.5': [321], '−4.8': [325], '−1.5': [327], 'days;': [328], '&lt;': [330], '.001).': [331], 'quality': [338], 'life.': [340], 'Twelve': [341], '(22%)': [343], 'required': [348], 'further': [349], 'procedures': [351], 'compared': [352], '3': [354], '(6%)': [355], '(odds': [360], 'ratio': [361], '[OR],': [362], '0.21;': [363], '95%': [364, 392], '0.04-0.86;': [366], '.03).': [369], 'Twenty-one': [370], '52': [373], 'catheter': [377], 'experienced': [379], 'adverse': [380], 'events': [381], 'vs': [382], '54': [385], '(OR,': [390], '4.70;': [391], '1.75-12.60;': [394], '.002).<h3>Conclusion</h3>Among': [397], 'previous': [405], 'pleurodesis,': [406], 'there': [407], 'IPCs': [413], 'patient-reported': [419], 'dyspnea.<h3>Trial': [420], 'Registration</h3>isrctn.org': [421], 'Identifier:': [422], 'ISRCTN87514420': [423]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1975166857', 'counts_by_year': [{'year': 2024, 'cited_by_count': 35}, {'year': 2023, 'cited_by_count': 31}, {'year': 2022, 'cited_by_count': 40}, {'year': 2021, 'cited_by_count': 49}, {'year': 2020, 'cited_by_count': 63}, {'year': 2019, 'cited_by_count': 56}, {'year': 2018, 'cited_by_count': 55}, {'year': 2017, 'cited_by_count': 50}, {'year': 2016, 'cited_by_count': 47}, {'year': 2015, 'cited_by_count': 48}, {'year': 2014, 'cited_by_count': 41}, {'year': 2013, 'cited_by_count': 36}, {'year': 2012, 'cited_by_count': 9}], 'updated_date': '2024-12-25T03:48:18.710054', 'created_date': '2016-06-24'}