Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1975111111', 'doi': 'https://doi.org/10.1002/glia.20181', 'title': 'Astrocytes in cerebral ischemic injury: Morphological and general considerations', 'display_name': 'Astrocytes in cerebral ischemic injury: Morphological and general considerations', 'publication_year': 2005, 'publication_date': '2005-04-21', 'ids': {'openalex': 'https://openalex.org/W1975111111', 'doi': 'https://doi.org/10.1002/glia.20181', 'mag': '1975111111', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15846806'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/glia.20181', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S147407642', 'display_name': 'Glia', 'issn_l': '0894-1491', 'issn': ['0894-1491', '1098-1136'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5074335170', 'display_name': 'Kiran S. Panickar', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I145608581', 'display_name': 'University of Miami', 'ror': 'https://ror.org/02dgjyy92', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145608581']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Kiran S. Panickar', 'raw_affiliation_strings': ['Department of Pathology, University of Miami School of Medicine, Miami, Florida'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, University of Miami School of Medicine, Miami, Florida', 'institution_ids': ['https://openalex.org/I145608581']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5111990004', 'display_name': 'Michael D. Norenberg', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I145608581', 'display_name': 'University of Miami', 'ror': 'https://ror.org/02dgjyy92', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145608581']}, {'id': 'https://openalex.org/I2799886695', 'display_name': 'Veterans Health Administration', 'ror': 'https://ror.org/05eq41471', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Michael D. Norenberg', 'raw_affiliation_strings': ['Biochemistry and Molecular Biology, University of Miami School of Medicine, Miami, Florida', 'Department of Pathology, University of Miami School of Medicine, Miami, Florida', 'Veterans Affairs Medical Center, Miami, Florida'], 'affiliations': [{'raw_affiliation_string': 'Biochemistry and Molecular Biology, University of Miami School of Medicine, Miami, Florida', 'institution_ids': ['https://openalex.org/I145608581']}, {'raw_affiliation_string': 'Veterans Affairs Medical Center, Miami, Florida', 'institution_ids': ['https://openalex.org/I2799886695']}, {'raw_affiliation_string': 'Department of Pathology, University of Miami School of Medicine, Miami, Florida', 'institution_ids': ['https://openalex.org/I145608581']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5111990004'], 'corresponding_institution_ids': ['https://openalex.org/I145608581', 'https://openalex.org/I2799886695'], 'apc_list': {'value': 4940, 'currency': 'USD', 'value_usd': 4940, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.6, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 292, 'citation_normalized_percentile': {'value': 0.992453, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '50', 'issue': '4', 'first_page': '287', 'last_page': '298'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11266', 'display_name': 'Neuroinflammation and Neurodegeneration Mechanisms', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11266', 'display_name': 'Neuroinflammation and Neurodegeneration Mechanisms', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10608', 'display_name': 'Neurogenesis and neuroplasticity mechanisms', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2806', 'display_name': 'Developmental Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T14144', 'display_name': 'Neurological Disease Mechanisms and Treatments', 'score': 0.9971, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/synaptogenesis', 'display_name': 'Synaptogenesis', 'score': 0.7591417}, {'id': 'https://openalex.org/keywords/excitotoxicity', 'display_name': 'Excitotoxicity', 'score': 0.6496748}, {'id': 'https://openalex.org/keywords/ischemic-injury', 'display_name': 'Ischemic injury', 'score': 0.48988694}, {'id': 'https://openalex.org/keywords/homeostasis', 'display_name': 'Homeostasis', 'score': 0.41438338}], 'concepts': [{'id': 'https://openalex.org/C65232495', 'wikidata': 'https://www.wikidata.org/wiki/Q1813773', 'display_name': 'Synaptogenesis', 'level': 2, 'score': 0.7591417}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.7238264}, {'id': 'https://openalex.org/C2779830541', 'wikidata': 'https://www.wikidata.org/wiki/Q1622829', 'display_name': 'Microglia', 'level': 3, 'score': 0.6934249}, {'id': 'https://openalex.org/C4746552', 'wikidata': 'https://www.wikidata.org/wiki/Q1456827', 'display_name': 'Neurogenesis', 'level': 2, 'score': 0.6554687}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.65541637}, {'id': 'https://openalex.org/C2781012912', 'wikidata': 'https://www.wikidata.org/wiki/Q901117', 'display_name': 'Excitotoxicity', 'level': 4, 'score': 0.6496748}, {'id': 'https://openalex.org/C541997718', 'wikidata': 'https://www.wikidata.org/wiki/Q188151', 'display_name': 'Ischemia', 'level': 2, 'score': 0.5447061}, {'id': 'https://openalex.org/C2993714741', 'wikidata': 'https://www.wikidata.org/wiki/Q188151', 'display_name': 'Ischemic injury', 'level': 3, 'score': 0.48988694}, {'id': 'https://openalex.org/C25498285', 'wikidata': 'https://www.wikidata.org/wiki/Q1981368', 'display_name': 'Neuroprotection', 'level': 2, 'score': 0.45304206}, {'id': 'https://openalex.org/C63645605', 'wikidata': 'https://www.wikidata.org/wiki/Q103191', 'display_name': 'Homeostasis', 'level': 2, 'score': 0.41438338}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.32532334}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.20412257}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.19370487}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.18184099}, {'id': 'https://openalex.org/C61174792', 'wikidata': 'https://www.wikidata.org/wiki/Q420510', 'display_name': 'Glutamate receptor', 'level': 3, 'score': 0.17604047}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.17451}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001253', 'descriptor_name': 'Astrocytes', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': True}, {'descriptor_ui': 'D001253', 'descriptor_name': 'Astrocytes', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D002545', 'descriptor_name': 'Brain Ischemia', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D002545', 'descriptor_name': 'Brain Ischemia', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001253', 'descriptor_name': 'Astrocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001253', 'descriptor_name': 'Astrocytes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002545', 'descriptor_name': 'Brain Ischemia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002545', 'descriptor_name': 'Brain Ischemia', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002450', 'descriptor_name': 'Cell Communication', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002450', 'descriptor_name': 'Cell Communication', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/glia.20181', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S147407642', 'display_name': 'Glia', 'issn_l': '0894-1491', 'issn': ['0894-1491', '1098-1136'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15846806', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.53}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 164, 'referenced_works': ['https://openalex.org/W1043684383', 'https://openalex.org/W1121615361', 'https://openalex.org/W1439525013', 'https://openalex.org/W1495656315', 'https://openalex.org/W1502035335', 'https://openalex.org/W1504954730', 'https://openalex.org/W1545401493', 'https://openalex.org/W1578226137', 'https://openalex.org/W1580693649', 'https://openalex.org/W1615263285', 'https://openalex.org/W1643614299', 'https://openalex.org/W166932304', 'https://openalex.org/W167549985', 'https://openalex.org/W1707282766', 'https://openalex.org/W1753183749', 'https://openalex.org/W1900227502', 'https://openalex.org/W1906569886', 'https://openalex.org/W1936866440', 'https://openalex.org/W1940299510', 'https://openalex.org/W1965869866', 'https://openalex.org/W1969702279', 'https://openalex.org/W1970862254', 'https://openalex.org/W1971293133', 'https://openalex.org/W1971792511', 'https://openalex.org/W1973656419', 'https://openalex.org/W1974967725', 'https://openalex.org/W1975372045', 'https://openalex.org/W1975414683', 'https://openalex.org/W1976365307', 'https://openalex.org/W1976754780', 'https://openalex.org/W1978757999', 'https://openalex.org/W1979033680', 'https://openalex.org/W1979168940', 'https://openalex.org/W1979406476', 'https://openalex.org/W1979612418', 'https://openalex.org/W1981705400', 'https://openalex.org/W1982373564', 'https://openalex.org/W1982943754', 'https://openalex.org/W1983465575', 'https://openalex.org/W1985315203', 'https://openalex.org/W1985482045', 'https://openalex.org/W1985616298', 'https://openalex.org/W1990139471', 'https://openalex.org/W1991973189', 'https://openalex.org/W1993141186', 'https://openalex.org/W1994042895', 'https://openalex.org/W1998476386', 'https://openalex.org/W1999357946', 'https://openalex.org/W2001116239', 'https://openalex.org/W2001320373', 'https://openalex.org/W2001688974', 'https://openalex.org/W2002361618', 'https://openalex.org/W2003410399', 'https://openalex.org/W2003861928', 'https://openalex.org/W2008554589', 'https://openalex.org/W2008951867', 'https://openalex.org/W2009377621', 'https://openalex.org/W2009588334', 'https://openalex.org/W201144505', 'https://openalex.org/W2011740038', 'https://openalex.org/W2013001358', 'https://openalex.org/W2018039414', 'https://openalex.org/W2018888668', 'https://openalex.org/W2020122762', 'https://openalex.org/W2020127912', 'https://openalex.org/W2020277172', 'https://openalex.org/W2021533801', 'https://openalex.org/W2022950883', 'https://openalex.org/W2025461456', 'https://openalex.org/W2027953381', 'https://openalex.org/W2029549981', 'https://openalex.org/W2031611126', 'https://openalex.org/W2032504205', 'https://openalex.org/W2032968014', 'https://openalex.org/W2033204154', 'https://openalex.org/W2033494272', 'https://openalex.org/W2034394488', 'https://openalex.org/W2035371282', 'https://openalex.org/W2035569448', 'https://openalex.org/W2036829402', 'https://openalex.org/W2037726739', 'https://openalex.org/W2040490831', 'https://openalex.org/W2041033879', 'https://openalex.org/W2042541531', 'https://openalex.org/W204348490', 'https://openalex.org/W2043985705', 'https://openalex.org/W2045744218', 'https://openalex.org/W2046801391', 'https://openalex.org/W2049789112', 'https://openalex.org/W2054247860', 'https://openalex.org/W2054603555', 'https://openalex.org/W2055390759', 'https://openalex.org/W2056645881', 'https://openalex.org/W2058539880', 'https://openalex.org/W2059826462', 'https://openalex.org/W2062073205', 'https://openalex.org/W2064046485', 'https://openalex.org/W2064645610', 'https://openalex.org/W2064716636', 'https://openalex.org/W2065358457', 'https://openalex.org/W2067211273', 'https://openalex.org/W2067502143', 'https://openalex.org/W2068286984', 'https://openalex.org/W2068546618', 'https://openalex.org/W2069279912', 'https://openalex.org/W2076344617', 'https://openalex.org/W2076699811', 'https://openalex.org/W2079180172', 'https://openalex.org/W2079356804', 'https://openalex.org/W2079696649', 'https://openalex.org/W2080322137', 'https://openalex.org/W2080408380', 'https://openalex.org/W2082809972', 'https://openalex.org/W2083156331', 'https://openalex.org/W2083393999', 'https://openalex.org/W2084654578', 'https://openalex.org/W2084761937', 'https://openalex.org/W2085763546', 'https://openalex.org/W2086129363', 'https://openalex.org/W2086157846', 'https://openalex.org/W2086559754', 'https://openalex.org/W2090081015', 'https://openalex.org/W2090246247', 'https://openalex.org/W2090295661', 'https://openalex.org/W2090780673', 'https://openalex.org/W2090833562', 'https://openalex.org/W2091114466', 'https://openalex.org/W2091343966', 'https://openalex.org/W2094920761', 'https://openalex.org/W2105012597', 'https://openalex.org/W2107020136', 'https://openalex.org/W2108529838', 'https://openalex.org/W2108541860', 'https://openalex.org/W2113210947', 'https://openalex.org/W2114484265', 'https://openalex.org/W2117088742', 'https://openalex.org/W2117523148', 'https://openalex.org/W2118625836', 'https://openalex.org/W2123397643', 'https://openalex.org/W2129567809', 'https://openalex.org/W2132823130', 'https://openalex.org/W2133093591', 'https://openalex.org/W2140175924', 'https://openalex.org/W2144303480', 'https://openalex.org/W2147715586', 'https://openalex.org/W2160935383', 'https://openalex.org/W2168391595', 'https://openalex.org/W2168422839', 'https://openalex.org/W2169334356', 'https://openalex.org/W221164160', 'https://openalex.org/W2215751532', 'https://openalex.org/W2327773189', 'https://openalex.org/W2397332493', 'https://openalex.org/W2400413823', 'https://openalex.org/W2409827897', 'https://openalex.org/W2742618151', 'https://openalex.org/W2792583460', 'https://openalex.org/W2890372342', 'https://openalex.org/W292176319', 'https://openalex.org/W4205207356', 'https://openalex.org/W4210981518', 'https://openalex.org/W4233150381', 'https://openalex.org/W5338072', 'https://openalex.org/W593057303'], 'related_works': ['https://openalex.org/W4388014052', 'https://openalex.org/W4295846911', 'https://openalex.org/W3011296224', 'https://openalex.org/W2531390848', 'https://openalex.org/W2409278910', 'https://openalex.org/W2377956979', 'https://openalex.org/W2368783536', 'https://openalex.org/W2019492885', 'https://openalex.org/W2004228152', 'https://openalex.org/W2001896618'], 'abstract_inverted_index': {'Abstract': [0], 'Asrocytic': [1], 'responses': [2], 'constitute': [3], 'one': [4], 'of': [5, 29, 33, 39, 45, 49, 59, 89], 'the': [6, 13, 57, 86, 92], 'earliest': [7], 'and': [8, 41, 47, 51, 69, 77], 'most': [9], 'prominent': [10], 'changes': [11], 'in': [12, 67, 91], 'CNS': [14, 93], 'following': [15], 'ischemic': [16, 60, 96], 'injury.': [17, 61, 97], 'Astrocytes': [18], 'are': [19, 80], 'known': [20], 'to': [21, 95], 'carry': [22], 'out': [23], 'critical': [24, 87], 'functions': [25], 'such': [26], 'as': [27], 'maintenance': [28], 'ionic': [30], 'homeostasis,': [31], 'prevention': [32], 'excitotoxicity,': [34], 'scavenging': [35], 'free': [36], 'radicals,': [37], 'provision': [38], 'nutrients': [40], 'growth': [42], 'factors,': [43], 'promotion': [44], 'neovascularization,': [46], 'support': [48], 'synaptogenesis': [50], 'neurogenesis': [52], 'that': [53], 'potentially': [54], 'may': [55], 'influence': [56], 'outcome': [58], 'This': [62, 83], 'article': [63, 84], 'reviews': [64], 'ischemia‐associated': [65], 'alterations': [66], 'astrocytes': [68, 90], 'their': [70], 'potential': [71], 'significance.': [72], 'Interactions': [73], 'with': [74], 'neurons,': [75], 'microglia,': [76], 'endothelial': [78], 'cells': [79], 'also': [81], 'considered.': [82], 'highlights': [85], 'role': [88], 'response': [94], '©': [98], '2005': [99], 'Wiley‐Liss,': [100], 'Inc.': [101]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1975111111', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 7}, {'year': 2021, 'cited_by_count': 12}, {'year': 2020, 'cited_by_count': 17}, {'year': 2019, 'cited_by_count': 13}, {'year': 2018, 'cited_by_count': 15}, {'year': 2017, 'cited_by_count': 16}, {'year': 2016, 'cited_by_count': 17}, {'year': 2015, 'cited_by_count': 21}, {'year': 2014, 'cited_by_count': 24}, {'year': 2013, 'cited_by_count': 16}, {'year': 2012, 'cited_by_count': 17}], 'updated_date': '2024-12-14T07:31:08.488021', 'created_date': '2016-06-24'}