Publication Information

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2262, 2403, 2450, 2518, 2564, 2643, 2684, 2724, 2811, 2852, 2888, 2895, 2904, 2963, 3083, 3097, 3110, 3168, 3182, 3187, 3263, 3273, 3312, 3347, 3350, 3385, 3403, 3430, 3451, 3494, 3596, 3623, 3733, 3825, 3976, 3999, 4045, 4066, 4093, 4203], 'contains': [19, 75, 270, 326, 3487, 3615], '42': [20, 271, 3974], 'exons.': [21, 272, 767], 'promoter': [23, 274, 1465, 2653, 3447, 3732, 3773, 3785, 3798, 3924], 'characterized': [25, 276, 764, 1478, 3261], 'by': [26, 164, 277, 415, 765, 774, 992, 1479, 1670, 1696, 1701, 1769, 1869, 2055, 2110, 2312, 2345, 2410, 2955, 3289, 3406, 3433, 3462, 3518, 4074, 4128, 4287, 4297, 4303, 4310, 4317, 4324, 4331, 4338, 4345, 4351, 4357, 4363, 4370, 4376, 4382, 4388, 4395, 4402, 4408, 4414, 4420, 4429, 4437, 4443, 4449, 4457, 4463, 4469, 4477, 4485, 4491, 4499], 'lack': [28, 279, 1481, 3564], 'a': [30, 95, 151, 248, 281, 346, 402, 499, 620, 658, 811, 815, 937, 942, 947, 952, 1240, 1449, 1461, 1475, 1483, 1513, 1525, 1536, 1546, 1760, 1896, 2074, 2077, 2287, 2300, 2507, 2512, 2541, 2565, 2569, 2735, 2862, 2866, 2922, 3106, 3111, 3163, 3169, 3197, 3373, 3446, 3488, 3548, 3557, 3566, 3636, 3838, 3857, 3880], 'TATAA': [31, 282, 1484, 3470, 3489, 3550, 3568], 'motif': [32, 283, 1485, 3507, 3569], 'presence': [35, 286, 1488, 2221, 3546, 3573], 'several': [37, 288, 3275, 3407, 3602], 'Sp1': [38, 289, 1492, 2789, 2913, 2945, 3618, 3628, 3830, 3836, 3859, 3869, 3890, 3919, 3945], 'binding': [39, 290, 1493, 2419, 3619, 3629, 3639, 3831], 'sites,': [40, 291, 3410, 3479, 3620, 3832], 'some': [41, 292, 3605], 'which': [43, 54, 93, 161, 190, 215, 228, 294, 305, 344, 412, 441, 466, 479, 779, 828, 989, 1857, 3252, 3453, 3607, 3749, 4071], 'appeared': [44, 295], 'to': [45, 82, 89, 296, 333, 340, 537, 1004, 1194, 1244, 1307, 1337, 1853, 2095, 2182, 2209, 2557, 2664, 2670, 2676, 2682, 2689, 2746, 2767, 2865, 3017, 3266, 3301, 3305, 3321, 3335, 3456, 3497, 3585, 3590, 3597, 3725, 3735, 3790, 3794, 3813, 3820, 3826, 3893, 3935, 4017], 'be': [46, 240, 297, 491, 1005, 1148, 3510, 3591, 3821], 'functional': [47, 298, 1491, 3549, 3567, 3701], 'transfected': [49, 300, 1470, 2733, 2759], 'HeLa': [50, 301, 1472, 2691, 2729, 3747, 3805, 3854], 'cells.': [51, 302, 3806], 'Comparison': [52, 303, 1422, 3358], 'withCol18a1,': [53, 304], 'encodes': [55, 94, 306, 345], 'α1(XVIII)': [57, 308, 1361], 'homologous': [60, 137, 311, 388, 676, 1006, 1289], 'with': [61, 208, 312, 459, 619, 638, 810, 933, 1429, 1999, 2189, 2267, 2314, 2458, 2706, 2734, 2760, 2782, 2861, 2880, 3123, 3179, 3183, 3204, 3254, 3314, 3366, 3571, 3655, 3780, 3856, 3863, 3888, 3896, 3907, 3917, 4060, 4086], 'α1(XV),': [62, 313], 'indicates': [63, 314], 'marked': [64, 315, 1436, 3413], 'structural': [65, 316, 626], 'homology': [66, 153, 317, 404, 1193], 'spread': [67, 318], 'throughout': [68, 319], 'two': [70, 105, 134, 171, 209, 321, 356, 385, 422, 460, 1445, 3101, 3248, 3388], 'genes.': [71, 135, 237, 322, 386, 488], 'mouse': [73, 324, 1215, 1335, 1371], 'Col18a1': [74, 325], 'one': [76, 327, 612, 831, 3158, 3627], 'exon': [77, 90, 328, 341, 808, 4024, 4115, 4277], 'more': [78, 329, 524, 833, 847], 'than': [79, 220, 330, 471, 525, 4131], 'COL15A1,': [80, 331], 'due': [81, 332], 'fact': [84, 335], 'thatCOL15A1': [85, 336], 'lacks': [86, 337], 'sequences': [87, 338, 1693, 2342, 2489, 3090, 3176, 3213, 3272, 3995, 4035, 4089], 'corresponding': [88, 339, 1243, 2094, 2864, 3300, 3865], '3': [91, 342, 2634, 3309], 'ofCol18a1,': [92, 343], 'cysteine-rich': [96, 347], 'sequence': [97, 348, 623, 983, 1192, 1456, 2406, 3303, 3490, 3580, 3640, 3681, 3809], 'motif.': [98, 349], 'Twenty-five': [99, 350], 'exons': [102, 138, 146, 149, 194, 353, 389, 397, 400, 445, 857, 1249, 2098, 2970, 3975], 'genes': [106, 357, 527, 670, 840, 1286, 1446], 'are': [107, 127, 162, 195, 202, 245, 358, 378, 413, 446, 453, 496, 605, 625, 674, 763, 780, 846, 990, 1202, 1205, 1291, 3608, 3873], 'almost': [108, 130, 359, 381], 'identical': [109, 128, 131, 360, 379, 382], 'size,': [111, 362], 'six': [112, 363], 'them': [114, 365], 'contain': [115, 366, 1191, 3598, 3827], 'conserved': [116, 367], 'split': [117, 368], 'codons,': [118, 369], 'locations': [121, 372], 'respective': [124, 375], 'exon-intron': [125, 376, 1211, 1416, 1439, 4081], 'junctions': [126, 377], 'or': [129, 380, 803, 832, 1744, 2060, 2068, 2375, 2384, 2794, 3862], 'include': [139, 390], 'closely': [141, 392], 'adjacent': [142, 393, 2315, 3367], 'first': [143, 213, 394, 464, 1990, 3633], 'pair': [144, 395], 'encoding': [150, 401, 671, 1256, 1287, 1431, 2979, 3209], 'thrombospondin-1': [152, 403], 'found': [154, 405, 1003, 3265, 3589, 3684, 3819], 'N-terminal': [157, 408, 944, 1184, 3271], 'noncollagenous': [158, 179, 409, 430, 945, 955, 994, 1185, 1208], 'domain': [159, 180, 410, 431, 614, 662, 770, 956], '1,': [160, 411, 2591, 2661], 'followed': [163, 414], 'most': [166, 191, 417, 442, 777, 3991], 'variable': [167, 418], 'part': [168, 419, 2980], 'genes,': [172, 207, 423, 458], 'covering': [173, 424, 2461, 3091, 3581], 'C-terminal': [175, 426, 954, 1207], 'half': [176, 427], 'their': [178, 429, 530, 645, 852, 1199, 3988], '1': [181, 432, 1800, 1836, 1841, 1929, 1957, 1967, 1978, 2005, 2234, 2622, 2761, 2784, 2795], 'beginning': [184, 435], 'collagenous': [187, 438, 513, 837, 949, 982, 987, 1200, 4423, 4431, 4451, 4471, 4479, 4493, 4501], 'portion,': [188, 439], 'after': [189, 440, 2809], 'homologous.': [196, 447], 'lengths': [198, 449, 2486], 'introns': [201, 452, 2052, 3978, 4038, 4064], 'not': [203, 454, 1694, 3509, 3914], 'similar': [204, 455, 3776], 'these': [206, 457, 672, 3781], 'exceptions,': [210, 461], 'namely': [211, 462], 'intron,': [214, 227, 465, 478], 'very': [217, 230, 468, 481, 3558], 'short,': [218, 469], 'less': [219, 470], '100': [221, 472, 2720], 'base': [222, 473, 788], 'pairs,': [223, 474], 'second': [226, 477, 2014], 'large,': [231, 482, 507], '50': [233, 484, 1790, 1904, 2252, 2711, 2725], 'kilobases,': [234, 485], 'both': [236, 487, 1188], 'It': [238, 489], 'can': [239, 490, 858], 'concluded': [241, 492], 'that': [242, 493, 528, 606, 663, 1145, 1430, 1443, 2023, 2620, 3025, 3177, 3372, 3562, 3894, 3944, 3965, 4120], 'COL15A1': [243, 494, 2470, 3706, 3802], 'andCol18a1': [244, 495], 'derived': [246, 497, 2510], 'from': [247, 498, 1448, 1557, 1665, 1712, 2103, 2215, 2506, 2511, 2526, 2568, 2816, 2849, 2939, 3160, 3325, 3556, 3583, 3722, 3729, 3787, 3810, 3929, 4015, 4279], 'common': [249, 500, 1450, 2542], 'ancestor.': [250, 501, 1451], 'family': [503], 'collagens': [505, 821, 1290], 'number': [510], 'known': [512, 3641], 'proteins': [514, 608], 'increasing.': [516], 'Nineteen': [517], 'genetically': [518], 'distinct': [519], 'vertebrate': [520], 'types': [522, 634, 650, 673, 823, 997], '30': [526, 1980, 3540, 4132], 'encode': [529], 'constitutive': [531], 'α': [532], 'chains': [533, 618, 1190], 'have': [534, 609, 635, 657, 830, 1001, 4137, 4205], 'been': [535, 636, 1002, 1143, 1222, 1251, 1305, 2988, 4138, 4206], 'identified': [536], 'date': [538], '(1Vuorio': [539, 677, 861], 'E.': [540, 678, 862, 1125, 1227], 'de': [541, 679, 863], 'Crombrugghe': [542, 680, 864], 'B.': [543, 681, 717, 865, 902], 'Annu.': [544, 588, 682, 866], 'Rev.': [545, 589, 683, 867], 'Biochem.': [546, 590, 684, 868, 2119], '1990;': [547, 685, 869, 4172], '59:': [548, 686, 870], '181-198Crossref': [549, 687, 871], 'Scopus': [550, 562, 580, 595, 688, 872, 1076, 1099, 1118, 1179, 1235, 1329, 1355, 1393, 1734, 1832, 1952, 2124, 2173, 2336, 2369, 3675, 4107, 4160, 4176, 4189, 4227], '(392)': [551, 689, 873], 'Google': [552, 564, 582, 597, 690, 708, 874, 893, 979, 1029, 1051, 1078, 1101, 1120, 1138, 1181, 1237, 1283, 1331, 1357, 1395, 1736, 1834, 1954, 2126, 2175, 2338, 2371, 3013, 3065, 3150, 3243, 3677, 4109, 4162, 4178, 4191, 4229, 4250], 'Scholar,': [553, 565, 583, 709, 734, 875, 894, 1030, 1052, 1079, 1102, 1121, 2162, 4163, 4179], '2Kivirikko': [554], 'K.I.': [555, 587], 'Ann.': [556], 'Med.': [557], '1993;': [558], '25:': [559], '113-126Crossref': [560], 'PubMed': [561, 579, 594, 978, 1028, 1050, 1075, 1098, 1117, 1137, 1178, 1234, 1282, 1328, 1354, 1392, 1733, 1831, 1951, 2123, 2172, 2335, 2368, 3012, 3064, 3149, 3242, 3674, 4106, 4159, 4175, 4188, 4226, 4249], '(194)': [563], '3Pihlajaniemi': [566], 'T.': [567, 968, 1018, 1106, 1127, 1229, 1272, 1321, 1349, 1577, 2143, 2164, 3002, 3054, 3139, 3232], 'Rehn': [568, 961, 1011, 1265, 2995, 3047, 3132, 3225], 'M.': [569, 962, 1012, 1104, 1123, 1225, 1266, 1726, 1824, 1944, 2996, 3048, 3133, 3226, 4233], 'Prog.': [570], 'Nucleic': [571, 4100, 4153, 4182], 'Acid': [572], 'Res.': [573, 4102, 4155, 4184], 'Mol.': [574], 'Biol.': [575, 970, 1020, 1042, 1129, 1274, 3004, 3056, 3141, 3234, 3664, 4241], '1995;': [576, 591, 3666], '50:': [577], '225-262Crossref': [578], '(78)': [581], '4Prockop': [584], 'D.J.': [585, 4237], 'Kivirikko': [586, 1316], '64:': [592], '403-434Crossref': [593], '(1377)': [596], 'Scholar).': [598, 919, 980, 1182, 1284, 1396, 1737, 2176, 2339, 3014, 3151, 3244, 3678, 4110, 4192], 'criteria': [600], 'classification': [602], 'as': [603, 1204, 1506, 1767, 1892, 2045, 2073, 2087, 2136, 2299, 2540, 2625, 2630, 2635, 2640, 2646, 2902, 3067, 3642, 3879, 4285], 'such': [607], 'at': [610, 1601, 1658, 1862, 1880, 1969, 1974, 1982, 2237, 2275, 2534, 2696, 3380, 3387], 'least': [611], 'triple-helical': [613, 661, 769], 'consisting': [615, 2483], 'polypeptide': [617], 'repeated': [621], 'Gly-X-Y': [622], 'components': [627], 'extracellular': [630], 'matrix.': [631], 'named': [637], 'Roman': [639], 'numerals': [640], 'order': [643, 3016], 'discovery.': [646], 'fibril-forming': [648], 'collagens,': [649], 'I,': [651], 'II,': [652], 'III,': [653], 'V,': [654], 'XI,': [656], 'single,': [659], 'uninterrupted': [660], 'available': [665], 'fibril': [667], 'formation.': [668], 'highly': [675], 'Scholar,5Sandell': [691], 'L.J.': [692, 696, 877, 881], 'Boyd': [693, 697, 878, 882], 'C.D.': [694, 698, 879, 883], 'Sandell': [695, 880], 'Extracellular': [699, 743, 884], 'Matrix': [700, 885], 'Genes.': [701, 886], 'Academic': [702, 747, 887], 'Press,': [703, 888], 'Inc.,': [704, 730, 889, 915], 'San': [705, 890], 'Diego1990:': [706, 891], '1-56Crossref': [707, 892], '6Chu': [710, 895], 'M.-L.': [711, 896], 'Prockop': [712, 897, 4236], 'D.': [713, 898, 1728, 1826, 1946], 'Royce': [714, 899], 'P.M.': [715, 900, 1341], 'Steinmann': [716, 901], 'Connective': [718, 903], 'Tissue': [719, 904], 'Its': [721, 906], 'Heritable': [722, 907], 'Disorders.': [723, 908], 'Molecular,': [724, 909], 'Genetics,': [725, 910], 'Medical': [727, 912], 'Aspects.': [728, 913], 'Wiley-Liss,': [729, 914], 'New': [731, 916], 'York1993:': [732, 917], '149-165Google': [733, 918], '7Bateman': [735], 'J.F.': [736], 'Lamandé': [737], 'S.R.': [738], 'Ramshaw': [739], 'J.A.M.': [740], 'Comper': [741], 'W.D.': [742], 'Matrix.': [744], '2.': [745], 'Harwood': [746], 'Publishers,': [748], 'Amsterdam1996:': [749], '22-67Google': [750], 'Scholar),': [751, 1139, 1238, 1358, 1835, 1955, 2127], 'those': [753], 'three': [756, 3339], 'major': [757, 3340, 3374, 3500, 4281], 'ones,': [758], 'COL1A1,COL1A2,': [759], 'COL2A1,': [760], 'COL3A1,': [762], '51–52': [766], 'Their': [768], 'coded': [772], '41–42': [775], 'exons,': [776, 3987], '54': [781], 'bp': [782, 2662, 2668, 2674, 2680, 2687, 3723, 3788, 3811, 4027, 4032, 4044], '1The': [783], 'abbreviations': [784], 'used': [785, 1505, 1891, 2011, 2072, 2298, 2574, 2587, 2651, 2901, 2950], 'are:': [786], 'bp,': [787, 4019], 'pair(s);': [789], 'kb,': [790, 3259], 'kilobase(s);': [791], 'PCR,': [792, 1993], 'polymerase': [793, 1901, 1961], 'reaction;': [795], 'Pipes,': [796, 2227], 'piperazine-N,N′-bis[2-ethanesulfonic': [797], 'acid];': [798], 'del,': [799], 'deletion.': [800], 'multiples': [804], 'thereof,': [805], 'each': [807, 1921, 2850, 3161, 3180, 3758, 3876], 'begins': [809], 'complete': [812, 921], 'codon': [813], 'glycine.': [816], 'class': [818], 'nonfibril-forming': [820], 'includes': [822], 'IV,': [824], 'VI–X,': [825], 'XII–XIX,': [827], 'all': [829, 2545, 2561, 3771, 3927, 3985], 'interruptions': [834], 'sequence.': [838], 'coding': [841, 4257], 'this': [843], 'heterogeneous': [844], 'group': [845], 'divergent': [848], 'structure,': [850], 'numbers': [853], 'sizes': [855, 2049, 2305, 3344, 3361, 4069], 'vary': [859, 4012, 4039], 'considerably': [860], '5Sandell': [876], 'primary': [922], 'structure': [923, 1242, 3526], 'α1(XV)': [927, 1301, 2984, 4261], 'consists': [929, 984, 3972], '1388': [931], 'residues,': [932], 'following': [935, 2658, 4114], 'domains:': [936], '25-residue': [938], 'putative': [939], 'signal': [940], 'peptide,': [941], '530-residue': [943], 'domain,': [946], '577-residue': [948], 'sequence,': [950], '256-residue': [953], '(8Kivirikko': [957, 1007, 1261, 2991, 3043, 3128, 3221], 'S.': [958, 1008, 1060, 1070, 1091, 1112, 1163, 1173, 1262, 1317, 1385, 1722, 1820, 1940, 2322, 2330, 2355, 2363, 2992, 3044, 3129, 3222, 4215], 'Heinämäki': [959, 1009, 1263, 2993, 3045, 3130, 3223], 'P.': [960, 1010, 1264, 2115, 2994, 3046, 3131, 3224, 4099, 4152, 4165], 'Honkanen': [963, 1013, 1267, 2997, 3049, 3134, 3227], 'N.': [964, 1014, 1034, 1268, 1343, 2117, 2998, 3050, 3135, 3228], 'Myers': [965, 1015, 1269, 1322, 2165, 2999, 3051, 3136, 3229], 'J.C.': [966, 1016, 1270, 1323, 2166, 3000, 3052, 3137, 3230], 'Pihlajaniemi': [967, 1017, 1105, 1126, 1228, 1271, 1320, 1348, 3001, 3053, 3138, 3231], 'J.': [969, 1019, 1041, 1128, 1273, 1573, 1718, 1816, 1936, 2139, 3003, 3055, 3140, 3233, 3663, 4219, 4240], 'Chem.': [971, 1021, 1043, 1130, 1275, 3005, 3057, 3142, 3235, 3665, 4242], '1994;': [972, 1022, 1044, 1072, 1095, 1114, 1131, 1175, 1276, 1389, 3006, 3058, 3143, 3236, 4223], '269:': [973, 1023, 1045, 1132, 1277, 3007, 3059, 3144, 3237], '4773-4779Abstract': [974, 1024, 1278, 3008, 3060, 3145, 3238], 'Full': [975, 1025, 1047, 1134, 1279, 3009, 3061, 3146, 3239, 3669, 3671, 4246], 'Text': [976, 1026, 1048, 1135, 1280, 3010, 3062, 3147, 3240, 3670, 3672, 4247], 'PDF': [977, 1027, 1049, 1136, 1281, 3011, 3063, 3148, 3241, 3673, 4248], 'nine': [986, 3351], 'domains,': [988], 'separated': [991], 'eight': [993], 'domains.': [995, 1209], 'Collagen': [996], 'XVIII': [1000, 1217, 1433], '9Muragaki': [1031], 'Y.': [1032, 1036, 1056, 1058, 1159, 1161], 'Abe': [1033], 'Ninomiya': [1035], 'Olsen': [1037, 1063, 1092, 1166, 1386], 'B.R.': [1038, 1064, 1093, 1167, 1387], 'Ooshima': [1039, 1061, 1164], 'A.': [1040, 1062, 1071, 1113, 1165, 1174, 1347, 1724, 1822, 1942, 2331, 2364, 4235], '4042-4046Abstract': [1046], '10Oh': [1053], 'S.P.': [1054, 1081, 1157, 1375], 'Kamagata': [1055, 1158], 'Muragaki': [1057, 1160], 'Timmons': [1059, 1090, 1162, 1384], 'Proc.': [1065, 1107, 1168, 2325, 2358], 'Natl.': [1066, 1108, 1169, 2326, 2359], 'Acad.': [1067, 1109, 1170, 2327, 2360], 'Sci.': [1068, 1110, 1171, 2328, 2361], 'U.': [1069, 1111, 1172, 2329, 2362], '91:': [1073, 1115, 1176], '4229-4233Crossref': [1074, 1177], '(161)': [1077, 1180], '11Oh': [1080], 'Warman': [1082, 1376], 'M.L.': [1083, 1377], 'Seldin': [1084, 1378], 'M.F.': [1085, 1379], 'Cheng': [1086, 1380], 'S.-D.': [1087, 1381], 'Knoll': [1088, 1382], 'J.H.M.': [1089, 1383], 'Genomics.': [1094, 1230, 1324, 1350, 1388, 1729, 1827, 1947, 4222], '19:': [1096, 1390, 4186], '494-499Crossref': [1097, 1391], '(118)': [1100, 1394], '12Rehn': [1103], '4234-4238Crossref': [1116], '(148)': [1119], '13Rehn': [1122], 'Hintikka': [1124, 1226], '13929-13935Abstract': [1133], 'it': [1141, 3411, 3532], 'has': [1142, 1220, 1250, 2987, 3837], 'suggested': [1144, 1474, 1768, 2475], 'they': [1146], 'should': [1147, 3554], 'called': [1149], 'multiplexins': [1150], '(multiple': [1151], 'triple': [1152], 'helix': [1153], 'domains': [1154, 1186, 1201], 'andinterruptions)': [1155], '(10Oh': [1156], 'thrombospondin,': [1195], 'seven': [1197, 1246, 2967], 'homologous,': [1203], 'organization': [1212, 1417, 4253], 'recently': [1221], 'determined': [1223, 2054, 2311, 2344, 2815, 3288, 3983, 4286, 4296, 4302, 4309, 4316, 4323, 4330, 4337, 4344, 4350, 4356, 4362, 4369, 4375, 4381, 4387, 4394, 4401, 4407, 4413, 4419, 4428, 4436, 4442, 4448, 4456, 4462, 4468, 4476, 4484, 4490, 4498], '(14Rehn': [1224], '1996;': [1231], '32:': [1232], '436-446Crossref': [1233], '(53)': [1236], 'partial': [1241], 'extreme': [1247, 2968, 3192, 3211, 4022], '3′': [1248, 2969, 4023], 'described': [1252, 2046, 2137, 2989], 'located': [1292, 1365, 3379, 3491], 'on': [1293, 1366, 1400, 2286, 2616, 3768], 'separate': [1294], 'chromosomes,': [1295], 'having': [1304], 'mapped': [1306, 3688], 'chromosome': [1308, 1338, 1368, 1372, 1715], '9': [1309], '(15Huebner': [1310], 'K.': [1311, 4239], 'Cannizzaro': [1312], 'L.A.': [1313], 'Jabs': [1314], 'E.W.': [1315], 'Manzone': [1318], 'H.': [1319], '1992;': [1325, 1730, 1828, 1948], '14:': [1326, 1731, 1829, 1949], '220-224Crossref': [1327], '(30)': [1330], 'Scholar)': [1332, 2372, 3066], 'its': [1334], 'counterpart': [1336], '4': [1339, 2639, 3900], '(16Hägg': [1340], 'Horelli-Kuitunen': [1342], 'Eklund': [1344], 'L.': [1345], 'Palotie': [1346], '1997;': [1351], '45:': [1352], '31-41Crossref': [1353], '(28)': [1356], 'whereas': [1359, 4020], '21': [1369], '10': [1373, 1795, 1797, 1878, 1913, 1923], '(11Oh': [1374], 'We': [1397], 'report': [1398], 'here': [1399], 'isolation': [1402, 1708, 2962, 3074, 3156], 'genomic': [1404, 1511, 1517, 1528, 1548, 1692, 2973, 3089, 3104, 3962, 4054, 4078], 'clones': [1405, 1499, 1663, 1716, 3095, 3185, 3963, 4055], 'characterization': [1413, 2964], 'entire': [1420, 3797, 4058], 'gene.': [1421, 2529, 2872, 3739, 3846, 3957, 4009], 'reveals': [1435], 'conservation': [1437], 'organization,': [1440], 'thus': [1441, 4147], 'indicating': [1442], 'derive': [1447], 'Analyses': [1452], '5′-flanking': [1455, 2488, 3278, 3423, 3482, 3529, 4005], 'theCOL15A1': [1458, 3845], 'using': [1460, 2376, 2432, 2819, 2830, 3033, 3436, 3713], 'computer': [1462, 3434], 'search': [1463], 'elements': [1466], 'deletion': [1468, 2481, 2754, 3849, 3877], 'constructs': [1469, 2482, 2650, 2755, 3774, 3850, 3928], 'into': [1471, 1683, 2520], 'cells': [1473, 2692, 2730, 3855], '"housekeeping': [1476], 'promoter"': [1477], 'apparently': [1490], 'sites.': [1494, 3578], 'Radioactively': [1495], 'labeled': [1496], 'cDNA': [1498, 2946, 3042, 3125, 3206, 3870], 'were': [1504, 1567, 1598, 1650, 1668, 1681, 1699, 1747, 1851, 1858, 1966, 2036, 2053, 2099, 2284, 2310, 2343, 2401, 2408, 2423, 2453, 2497, 2503, 2586, 2693, 2731, 2758, 2780, 2805, 2900, 2953, 3121, 3333, 3354, 3533, 3727, 3743, 3851, 3982, 4072], 'probes': [1507, 2460], 'screening': [1509, 3246], 'libraries:': [1512], 'lung': [1515], 'fibroblast': [1516], 'library': [1518, 1529, 1540, 1549, 3024, 3113, 3201], 'λ': [1521, 1743], 'FIXTMvector': [1522], '(944201;': [1523], 'Stratagene),': [1524, 1544], 'leukocyte': [1527, 3108], 'vector': [1532, 1553, 2614, 2791, 2801, 2894, 2898, 2911, 3116, 3861, 3866, 3892, 3912, 3921], 'EMBL-3': [1533], '(HL1006d;': [1534], 'CLONTECH),': [1535], 'lymphocyte': [1538, 3199], 'cosmid': [1539, 1552, 1745, 2069, 2513, 3112, 3171, 3200], 'pWE15': [1542], '(951203;': [1543], 'PJB8': [1554, 3117], '(a': [1555], 'gift': [1556, 2923], 'Dr.': [1558, 2925], 'Leena': [1559], 'Ala-Kokko,': [1560], 'University': [1561, 2398], 'Oulu,': [1563], 'Finland).': [1564], 'screenings': [1566, 3070], 'performed': [1568, 2135, 2879, 3709], 'under': [1569, 2018, 2455, 2914], 'stringent': [1570, 2456], 'conditions': [1571, 1965, 2021, 2457], '(17Sambrook': [1572, 2138], 'Fritsch': [1574, 2140], 'E.F.': [1575, 2141], 'Maniatis': [1576, 2142], 'Molecular': [1578, 2144], 'Cloning:': [1579, 2145], 'A': [1580, 2146, 2177, 2549, 3296, 3717, 3764], 'Laboratory': [1581, 2147], 'Manual.': [1582, 2148], '2nd': [1583, 2149], 'Ed.': [1584, 2150], 'Cold': [1585, 1589, 2151, 2155], 'Spring': [1586, 1590, 2152, 2156], 'Harbor': [1587, 2153], 'Laboratory,': [1588, 2154], 'Harbor,': [1591, 2157], 'NY1989:': [1592, 2158], '7.58,': [1593, 2159], '9.1-7.65,': [1594, 2160], '9.62Google': [1595, 2161], 'Scholar):': [1596], 'hybridizations': [1597], 'carried': [1599, 1651, 3744], 'out': [1600, 1652, 3745], '41': [1602, 3977], '°C': [1603, 1984, 2239, 2698], '50%': [1605], '(v/v)': [1606], 'formamide': [1607], '5×': [1609], 'SSC': [1610, 1612], '(1×': [1611], '=': [1613, 1789], '0.15m': [1614], 'NaCl,': [1615, 2232, 2251], '0.015': [1616], 'm': [1617], 'sodium': [1618, 2254], 'citrate,': [1619], 'pH': [1620, 1793, 1916, 2228, 2256], '6.8),': [1621], '1%': [1622, 1627, 1630], '(w/v)': [1623, 1642], 'bovine': [1624, 1805], 'serum': [1625, 1806], 'albumin,': [1626], 'Ficoll': [1628], '(w/v),': [1629, 1632], 'polyvinylpyrrolidone': [1631], '0.25': [1633], 'mg': [1634], 'denatured': [1636], 'salmon': [1637], 'sperm': [1638], 'DNA/ml,': [1639], '0.1%': [1641, 1656, 1909], 'SDS.': [1643], 'final': [1645], 'washes': [1646], 'filters': [1649], '0.5×': [1654], 'SSC,': [1655], 'SDS': [1657], '65': [1659], '°C.': [1660, 1864, 1882], 'positive': [1662, 2905, 3249], 'picked': [1664], 'libraries': [1667], 'analyzed': [1669, 2285, 2409], 'restriction': [1671, 1679, 2058, 2504, 2532, 2553, 2584, 4304, 4318, 4332, 4339, 4364, 4389, 4421], 'enzyme': [1672, 2833], 'mapping': [1673], 'Southern': [1675, 4075], 'blotting,': [1676], 'suitable': [1678], 'fragments': [1680, 1711, 2040, 2283, 2309, 2502, 3035, 3342, 3365], 'subcloned': [1682, 2519, 2624], 'plasmid': [1685, 2765, 2941, 2957], 'pBluescript': [1686], 'SK': [1687], '(Stratagene).': [1688], 'Gaps': [1689], 'covered': [1695, 4056], 'subclones': [1698], 'filled': [1700], 'PCR': [1703, 1898, 2017, 2081], 'method': [1704, 2351, 2737], 'designed': [1705], 'end': [1710], 'yeast': [1713, 2295], 'artificial': [1714], '(18Kere': [1717, 1815, 1935], 'Nagaraja': [1719, 1817, 1937], 'R.': [1720, 1818, 1938, 4231], 'Mumm': [1721, 1819, 1939], 'Ciccodicola': [1723, 1821, 1941], "D'Urso": [1725, 1823, 1943], 'Schlessinger': [1727, 1825, 1945], '241-248Crossref': [1732, 1830, 1950], '(116)': [1735, 1833, 1953], '100-ng': [1738], 'aliquots': [1739], 'isolated': [1742, 2109, 3311, 3324], 'DNA': [1746, 1845, 2070, 2379, 2393, 2846, 3298, 3958], 'blunt': [1748], 'end-digested': [1749], 'separately': [1750], 'withAluI,': [1751], 'EcoRV,': [1752], 'HaeIII,HincII,': [1753], 'PvuII,': [1754], 'RsaI,': [1755], 'SmaI,': [1756], 'StuI': [1758], '20-μl': [1761], 'reaction': [1762, 1995], 'containing': [1763, 1899, 2552, 4030], 'appropriate': [1765], 'buffer': [1766, 1784, 1788, 1902, 2248], 'supplier': [1771], 'enzymes': [1774], '(Amersham': [1775, 2412], 'Pharmacia': [1776, 2198, 2413], 'Biotech).': [1777, 2199, 2414], 'Next,': [1778], '2.5': [1779], 'μl': [1780, 1809, 1837, 1842, 1872, 1884, 2001, 2006, 2246], '10×': [1782], 'ligation': [1783, 1787, 1888], '(1': [1785], '×': [1786, 2204], 'mm': [1791, 1798, 1905, 1914, 1919, 2226, 2231, 2235, 2250, 2253, 2718], 'Tris,': [1792], '7.8,': [1794], 'mmMgCl2,': [1796, 1908], 'dithiothreitol,': [1799], 'mmATP,': [1801], '25': [1803], 'μg/ml': [1804, 2726], 'albumin),': [1807], '0.5': [1808], '5': [1811, 2024, 2031, 2645, 2775], 'μm': [1812], 'linker': [1813, 1933, 2034, 2550], 'solution': [1814], 'water,': [1839, 2003], 'T4': [1844, 2190], 'ligase': [1846], '(New': [1847], 'England': [1848], 'Biolabs': [1849], 'Inc.)': [1850], 'added': [1852], 'individual': [1855], 'reactions,': [1856], 'then': [1859, 3319], 'incubated': [1860], 'overnight': [1861], '12': [1863], 'incubation': [1866], 'was': [1867, 1890, 1997, 2010, 2071, 2108, 2134, 2187, 2207, 2260, 2265, 2297, 2538, 2555, 2573, 2623, 2814, 2828, 2847, 2854, 2859, 2878, 2921, 2937, 3029, 3202, 3260, 3264, 3287, 3310, 3318, 3404, 3428, 3588, 3649, 3818, 3913], 'stopped': [1868], 'adding': [1870], '75': [1871], 'water': [1874], 'heating': [1876], 'min': [1879, 1968, 1979], '95': [1881], 'Two': [1883, 4193], 'diluted': [1887, 1998], 'mixture': [1889, 1996, 2264], 'template': [1894, 2075], '10-μl': [1897], 'Taq': [1900, 1960], '(Promega;': [1903], 'KCl,': [1906], '1.7': [1907], 'Triton': [1910], 'X-100,': [1911], 'Tris-Cl,': [1915], '9.0),': [1917], '0.2': [1918], 'deoxynucleotide,': [1922], 'pmol': [1924, 1930, 2025, 2032], 'gene-specific': [1926, 2028], '23-mer': [1927], 'primer,': [1928], '25-mer': [1932], 'primer': [1934, 2029, 2035, 2551], 'unit': [1958], '(Promega).': [1962, 2824, 2836], 'amplification': [1964], '94': [1970], '°C,': [1971, 1976], '45': [1972], 's': [1973, 1981], '60': [1975], '72': [1983], '35': [1986], 'cycles.': [1987], 'After': [1988, 2243, 3766], 'round': [1991, 2015], '250': [2000], 'dilution': [2009], 'same': [2020, 2085, 3022], 'except': [2022], 'nested': [2027], 'used.': [2037, 2100], 'synthesized': [2039, 2388], 'wereEcoRI-digested,': [2041], 'subcloned,': [2042], 'sequenced': [2044, 3429], 'below.': [2047], 'either': [2056, 2373, 2783], 'sequencing,': [2057], 'mapping,': [2059], 'PCR.': [2061, 2079], '2': [2062, 2467, 2629, 2717, 4065], 'ng': [2063], 'relevant': [2066], 'lambda': [2067, 2974, 3023, 3165], '50-μl': [2078], 'mixtures': [2082], 'contained': [2083, 3175], 'ingredients': [2086], 'above,': [2088], 'sense': [2090], 'antisense': [2092], 'primers': [2093, 2387], 'flanking': [2097], 'Total': [2101], 'RNA': [2102, 2214, 3323], 'cultured': [2104, 3326], 'skin': [2106, 2217, 3328], 'fibroblasts': [2107, 2218], 'guanidium': [2111], 'isothiocyanate-chloroform-phenol': [2112], 'extraction': [2113], '(19Chomczynski': [2114], 'Sacchi': [2116], 'Anal.': [2118], '1987;': [2120, 2169, 4103, 4156], '162:': [2121], '156-159Crossref': [2122], '(63183)': [2125], 'S1': [2130, 2271, 3290, 3337, 3463, 3519, 4288], 'nuclease': [2131, 2272, 3291, 3336, 3464, 3520, 4289], 'protection': [2132, 3292, 3465, 3521], 'experiment': [2133], '20Pihlajaniemi': [2163], 'Methods': [2167, 4170], 'Enzymol.': [2168, 4171], '145:': [2170], '213-222Crossref': [2171], '(17)': [2174], '574-bpSacI-BanI': [2178], 'fragment': [2179, 2867, 3299], '(nucleotides': [2180], '−469': [2181, 3304], '+112': [2183, 3306], 'Fig.': [2185, 3308, 3416, 3611], '3)': [2186], '5′-end-labeled': [2188, 3313], 'polynucleotide': [2191], 'kinase': [2192], '[γ-32P]ATP': [2194], '(3000': [2195], 'Ci/mmol,': [2196], 'Amersham': [2197], 'double-stranded': [2201], 'probe': [2202, 2863, 3317], '(3': [2203], '105': [2205], 'cpm)': [2206], 'hybridized': [2208, 2454, 2860, 3320], '20': [2210, 2279, 2292], 'μg': [2211, 2293, 2712, 2762, 2776, 2785, 2796], 'total': [2213, 2845, 3322], '80%': [2223], 'formamide,': [2224], '40': [2225], '6.4,': [2229], '400': [2230], 'EDTA': [2236], '67': [2238], '15': [2241], 'h.': [2242], 'hybridization,': [2244], '300': [2245], '(280': [2249], 'acetate,': [2255], '4.5,': [2257], '4.5': [2258], 'mmZnSO4)': [2259], 'added,': [2261], 'digested': [2266], '800': [2268], 'units': [2269], '(Boehringer': [2273], 'Mannheim)': [2274], 'room': [2276], 'temperature': [2277], 'min.': [2280], 'protected': [2282, 2308, 3341, 3364], '6%': [2288], 'polyacrylamide': [2289], 'sequencing': [2290, 2317, 3369, 3959], 'gel.': [2291], 'tRNA': [2296], 'negative': [2301, 2903, 3909], 'control.': [2302], 'exact': [2304], 'comparison': [2313], 'dideoxynucleotide': [2316, 2348, 3368], 'reactions': [2318, 3370], '(21Sanger': [2319, 2352], 'F.': [2320, 2353], 'Nicklen': [2321, 2354], 'Coulson': [2323, 2356], 'A.R.': [2324, 2357], '1977;': [2332, 2365], '74:': [2333, 2366], '5463-5467Crossref': [2334, 2367], '(52658)': [2337, 2370], 'nucleotide': [2341, 2405, 3384], 'Sanger': [2347], 'termination': [2350], 'manually': [2374], 'an': [2377, 2390, 3255, 3381, 4294, 4300, 4307, 4314, 4321, 4328, 4335, 4342, 4348, 4354, 4360, 4367, 4373, 4379, 4385, 4392, 4399, 4405, 4411, 4417, 4426, 4434, 4440, 4446, 4454, 4460, 4466, 4474, 4482, 4488, 4496], 'automated': [2378], 'sequencer': [2380], '(Applied': [2381], 'Biosystems).': [2382], 'Vector-specific': [2383], 'sequence-specific': [2385], '17-mer': [2386], 'Applied': [2391], 'Biosystems': [2392], 'synthesizer': [2394], '(Department': [2395], 'Biochemistry,': [2397], 'Oulu)': [2400], 'used,': [2402], 'data': [2407], 'DNASIS': [2411], 'Consensus': [2415], 'sites': [2416, 2585, 3460, 3658, 3691, 4095, 4145], 'transcription': [2421, 3281, 3375, 3458, 3477, 3501, 3535, 3552, 3576, 3603, 3689, 3815, 4282], 'factors': [2422], 'searched': [2424], 'Transcription': [2428, 3438], 'Factor': [2429, 3439], 'Data': [2430, 3440], 'Base': [2431, 3441], 'Sequence': [2434], 'Analysis': [2435, 2889], 'software': [2436], 'package,': [2437], 'Version': [2438], '8.0': [2439], '(Genetics': [2440], 'Computer': [2441], 'Group,': [2442], 'Inc.).': [2443], 'Human': [2444], 'adult': [2445], 'multitissue': [2446], 'Northern': [2447], 'blots': [2448], '(7760-1': [2449], '7759-1;': [2451], 'CLONTECH)': [2452], '32P-labeled': [2459], '33': [2462], 'kb': [2463, 3276, 3420, 4002, 4048], 'intron': [2466, 3989, 4295, 4301, 4308, 4315, 4322, 4329, 4336, 4343, 4349, 4355, 4361, 4368, 4374, 4380, 4386, 4393, 4400, 4406, 4412, 4418, 4427, 4435, 4441, 4447, 4455, 4461, 4467, 4475, 4483, 4489, 4497], 'manner': [2474], "manufacturer's": [2478, 2748], 'protocol.': [2479, 2749], 'Five': [2480], 'different': [2485, 2583, 3034, 3848], 'made.': [2498], 'All': [2499, 2948], 'enzyme-digested': [2505], 'HindIII': [2508, 2566], 'subclone': [2509], 'clone': [2514, 2975, 3027, 3126, 3159, 3166, 3172, 3207], 'HG-23': [2515], '(Fig.': [2516, 2977, 3085, 3099, 3294, 3356, 3504, 3696, 3762, 3899, 3979], '1)': [2517, 2978], 'pGL2-Basic': [2522, 2570, 2893, 3911], 'Vector': [2523, 2571], '(Promega)': [2524, 2572, 2899], 'upstream': [2525, 3393], 'luciferase': [2528, 2753, 2778, 2812, 2821, 2870, 3737, 3777, 3885, 3904], 'An': [2530], 'EspI': [2531], 'site': [2533, 2567, 3283, 3377, 3503, 3630, 3645, 3817, 4113, 4284], 'position': [2536, 2611], '+27': [2537, 3726], 'utilized': [2539], '3′-end': [2543, 2559, 4268], 'constructs.': [2548, 3716], 'sitesEspI-SalI-HindIII': [2554], 'attached': [2556], 'constructs,': [2563, 2582], 'subcloning.': [2576], 'As': [2577], '5′-ends': [2579], '(HindIII': [2588], 'del': [2590, 2594, 2597, 2601, 2605, 2621, 2628, 2633, 2638, 2644, 2660, 2666, 2672, 2678, 2685], 'HincII': [2592], '2,XhoI': [2595], '3,': [2598, 2673], 'XbaI': [2599], '4,': [2602, 2679, 3763], 'andSacI': [2603], '5).': [2606], 'Accordingly,': [2607], '5′': [2609, 3212, 3720], 'subcloning': [2610], 'depended': [2615], 'construct,': [2618], 'so': [2619, 3561], 'aHindIII': [2626], 'fragment,': [2627, 2632, 2637, 2642, 3786], 'aSmaI-HindIII': [2631], 'aXhoI-HindIII': [2636], 'aNheI-HindIII': [2641], 'aSacI-HindIII': [2647], 'fragment.': [2648, 2947], 'Deletion': [2649], 'analysis': [2654, 3293, 3435, 3712], 'consisted': [2655], 'fragments:': [2659], '−3598': [2663, 3724], '+27;': [2665, 2671, 2677, 2683], '2,': [2667], '−2615': [2669], '−1858': [2675], '−1117': [2681], '5:': [2686], '−474': [2688, 3584, 3789, 3812], '+27.': [2690], 'routinely': [2694], 'maintained': [2695], '37': [2697], "Dulbecco's": [2700], 'modified': [2701], "Eagle's": [2702], 'medium': [2703], '(Imperial)': [2704], 'supplemented': [2705], '10%': [2707], 'fetal': [2708], 'calf': [2709], 'serum,': [2710], 'ascorbate': [2714], 'per': [2715], 'ml,': [2716], 'glutamine,': [2719], 'units/ml': [2721], 'penicillin,': [2723], 'streptomycin.': [2728], 'transiently': [2732], 'liposome-based': [2736], '(DOTAP': [2738], 'liposomal': [2739], 'transfection': [2740, 2770, 2839, 2952, 3741], 'reagent': [2741], 'kit,': [2742], 'Boehringer': [2743], 'Mannheim),': [2744], 'according': [2745], 'Briefly,': [2750], 'various': [2752, 3714, 4052], '(5': [2756], 'μg)': [2757], 'pCMV-β-galactosidase': [2764], '(CLONTECH)': [2766], 'normalize': [2768, 2838], 'efficiencies.': [2771], 'For': [2772], 'cotransfection': [2773, 2843, 3916], 'experiments,': [2774, 2844, 3757], 'plasmids': [2779, 2949], 'cotransfected': [2781, 3852], 'expression': [2790, 2800, 2910, 3860, 3891, 3920], '(pEVR2/Sp1': [2792], 'plasmid)': [2793], 'control': [2799, 2915, 2935, 3898, 3910], '(pEVR2/0': [2802], 'plasmid).': [2803], 'Cells': [2804], 'harvested': [2806], '24': [2807], 'h': [2808], 'transfection,': [2810], 'activity': [2813, 2827, 3799, 3886, 3905, 3925], 'cell': [2817], 'extracts': [2818], 'assay': [2822, 2834, 3522, 4290], 'system': [2823, 2835], 'β-galactosidase': [2826, 2832, 3769], 'measured': [2829], 'To': [2837, 3087, 3189, 3698], 'efficiency': [2840], 'extracted': [2848], 'sample,': [2851], 'Dot-blot': [2853], 'performed.': [2855], 'nitrocellulose': [2857], 'membrane': [2858], 'reporter': [2871, 3710, 3738], 'Densitometry': [2873], 'scanning': [2874], 'autoradiograms': [2877], 'GelWorks': [2882], '1D': [2883], 'program': [2884, 3444], '(UVP': [2885], 'Gel': [2886], 'Documentation': [2887], 'System,': [2890], 'GDS8000).': [2891], 'pGL2-Control': [2897], 'controls,': [2906], 'respectively.': [2907], 'CMV': [2918], 'promoter,': [2919, 3707], 'pEVR2/Sp1,': [2920], 'Suske': [2926], '(Institut': [2927], 'für': [2928], 'Molekularbiologie': [2929], 'und': [2930], 'Tumorforschung,': [2931], 'Marburg,': [2932], 'Germany).': [2933], 'pEVR2/0': [2936], 'obtained': [2938, 3517, 3887, 3895, 3906, 4073], 'pEVR2/Sp1': [2942], 'lacking': [2943], 'purified': [2954], 'midi': [2958], 'kit': [2959], '(Qiagen).': [2960], 'HLF-15': [2976, 3028, 3098], 'previously': [2990], 'In': [3015], 'isolate': [3018], 'additional': [3019, 3102], 'clones,': [3020, 3078, 3250], 'yielded': [3026], 'screened': [3030, 3122, 3203], 'four': [3031, 3616, 3828], 'times': [3032], 'probes.': [3068], 'These': [3069, 3174, 3941], 'resulted': [3071, 3153], 'five': [3076, 3755], 'new': [3077, 3637], 'HLF-3,': [3079], 'HLF-5,': [3080], 'HLF-13,': [3081], 'HLF-17,': [3082], 'HLF-18': [3084], '1).': [3086, 3980], 'find': [3088], 'gap': [3093], 'between': [3094, 3449, 3492, 4042], 'HLF-13': [3096, 3186], '1),': [3100], 'libraries,': [3105], 'library,': [3109, 3162], '(see': [3118, 4291], '"Experimental': [3119], 'Procedures"),': [3120], 'PF-19': [3127], 'This': [3152, 3245, 3316, 3506, 3613, 3679], '12-kb': [3164], 'HL-1-1': [3167], '30-kb': [3170], 'C-1-8-1.': [3173], 'overlapped': [3178], 'other': [3181, 3408, 4194], 'HLF-15.': [3188], 'characterize': [3190], '5′-end': [3193, 4264], 'gene,': [3196], 'F-10': [3208], 'cDNAs': [3220], 'gave': [3247], 'HG-23,': [3253], 'insert': [3256], '38': [3258], 'further': [3262, 3431], 'code': [3267], 'missing': [3270], 'also': [3274, 3626], 'sequences.': [3279], 'initiation': [3282, 3376, 3409, 3459, 3536, 3553, 3577, 3690], '2).': [3295, 3357], 'double-strandedSacI-BanI': [3297], 'γ-32P.': [3315], 'fibroblasts.': [3329], 'When': [3330], 'hybrids': [3332], 'subjected': [3334], 'digestion,': [3338], '120,': [3345], '164,': [3346], '165': [3348], 'nucleotides': [3349, 3392, 3541, 3582], 'minor': [3352], 'bands': [3353], 'detected': [3355, 3650], 'indicated': [3371, 3964], 'adenosine': [3382], '(A)': [3383], 'another': [3386], 'thymidines': [3389], '(T)': [3390], '44–45': [3391], 'this.': [3395], 'Because': [3396, 3807], 'former': [3398], 'showed': [3399], 'stronger': [3401], 'band': [3402], 'accompanied': [3405], '+1': [3414], '3.': [3417, 3612], 'About': [3418], '3.6': [3419, 4001], 'region': [3424, 3483, 3614, 4006], 'studied': [3432], 'program.': [3442], 'predicted': [3445, 3461, 3499], 'area': [3448], '−398': [3450], '−142,': [3452], 'corresponds': [3454], 'well': [3455], 'assay.': [3466], 'There': [3467], 'no': [3469], 'box': [3471], 'vicinity': [3474], 'start': [3478, 3502, 3555, 3644, 3657, 3816, 4283], 'but': [3480], '−404': [3493], '−400': [3495], 'relative': [3496, 3884], '3).': [3505, 3697], 'may': [3508], 'functional,': [3511, 3534], 'however,': [3512], 'view': [3514], 'results': [3516, 3942], '(and': [3523], 'overall': [3525], 'region).': [3530], 'If': [3531], 'would': [3537], 'occur': [3538], 'downstream.': [3542], 'Furthermore,': [3543], 'box,': [3551], 'precise': [3559], 'area,': [3560], 'agrees': [3570], 'multiple': [3575, 3643, 3656], 'ATG': [3587], 'rich': [3592, 3822], 'G+C': [3594, 3824], '(68.4%)': [3595], 'consensus': [3599, 3680, 4088], 'motifs': [3600], 'factors,': [3604], 'shown': [3609], 'potential': [3617, 3829, 3839], 'example,': [3622], 'there': [3624], 'intron.': [3634], 'Recently': [3635], 'protein': [3638], 'element': [3646], 'downstream': [3647, 3685], '(MED-1)': [3648], 'many': [3652], 'TATAA-less': [3653], 'promoters': [3654], '(22Ince': [3659], 'T.A.': [3660], 'Scotto': [3661], 'K.W.': [3662], '270:': [3667], '30249-30252Abstract': [3668], '(138)': [3676], 'GCTCC(C/G)': [3682], 'COL15A1gene': [3695], 'investigate': [3699], 'properties': [3702], 'we': [3708, 3833], 'deletions': [3715, 3721], 'series': [3718], 'constructed': [3728], 'linked': [3734], 'Transient': [3740], 'experiments': [3742], 'cells,': [3748], 'express': [3750], 'XV,': [3753], 'independent': [3756], 'run': [3759], 'duplicate': [3761], 'andB).': [3765], 'normalization': [3767], 'activity,': [3770], 'exhibited': [3775], 'activity.': [3778], 'Consistent': [3779], 'data,': [3782], 'shortest': [3784, 3939], '+27,': [3791], 'sufficient': [3793], 'give': [3795], 'investigated': [3834], 'whether': [3835], 'role': [3840], 'regulation': [3843, 3950], 'without': [3867], '(control).': [3871], 'Results': [3872], 'expressed': [3874], 'construct': [3878, 3934], 'ratio': [3881], 'C).': [3901], 'Although': [3902], 'basal': [3903], 'changed,': [3915], 'induced': [3922], '5.5-fold': [3930], 'longest': [3933], '10.3-fold': [3936], 'one.': [3940], 'suggest': [3943], 'involved': [3947], 'Sequences': [3981], 'junctions,': [3990], 'intronic': [3994], 'reasonable': [3997], 'Exons': [4010], '1–41': [4011], '36': [4016], '548': [4018], '1119': [4026], 'length,': [4029], '908': [4031], '3′-untranslated': [4034], '(TableI).': [4036], 'length': [4041], '89': [4043], '55': [4047], '(Table': [4049, 4083], 'I).': [4050], 'overlapping': [4053], 'exception': [4062], '9,': [4067], 'blotting': [4076], 'DNA.': [4079], 'boundaries': [4082], 'II)': [4084], 'agree': [4085], 'published': [4087], 'splice': [4091, 4198], 'donor': [4092, 4112, 4144], 'acceptor': [4094], '(23Shapiro': [4096, 4149], 'M.B.': [4097, 4150, 4167], 'Senapathy': [4098, 4151], 'Acids': [4101, 4154, 4183], '15:': [4104, 4157], '7155-7174Crossref': [4105, 4158], '(1971)': [4108, 4161], '6': [4116], 'unusual': [4118], 'normally': [4122], 'invariant': [4123], 'GT': [4124], 'dinucleotide': [4125], 'replaced': [4127], 'GC.': [4129], 'Fewer': [4130], 'examples': [4133, 4195], 'GC': [4135, 4197], 'donors': [4136, 4199], 'observed': [4139], 'among': [4140], 'thousands': [4142], 'catalogued': [4146], 'far': [4148], '24Senapathy': [4164], 'Shapiro': [4166], 'Harris': [4168], 'N.L.': [4169], '183:': [4173], '252-278Crossref': [4174], '(624)': [4177], '25Jackson': [4180], 'I.J.': [4181], '1991;': [4185], '3795-3798Crossref': [4187], '(278)': [4190], 'genes,COL4A1': [4202], 'COL7A1,': [4204], 'reported': [4207], '(26Christiano': [4208], 'A.M.': [4209], 'Hoffman': [4210], 'G.G.': [4211], 'Chung-Honet': [4212], 'L.C.': [4213], 'Lee': [4214], 'Wen': [4216], 'C.': [4217], 'Uitto': [4218], 'Greenspan': [4220], 'D.S.': [4221], '21:': [4224], '169-179Crossref': [4225], '(159)': [4228], 'Scholar,27Soininen': [4230], 'Huotari': [4232], 'Ganguly': [4234], 'Tryggvason': [4238], '1989;': [4243], '264:': [4244], '13565-13571Abstract': [4245], 'Scholar).Table': [4251], 'IExon-intron': [4252], 'collagenNo.Location': [4262], 'exonLocation': [4266], 'exonExon': [4270], 'sizeIntron': [4271], 'sizeFeaturesbpbp15′-UTRaUTR,': [4272], 'untranslated': [4273], 'region.NC1120bSize': [4274], 'calculated': [4278], '"Results").89cSize': [4292], 'sequencing.2NC1NC189∼55,000dSize': [4298], 'mapping.3NC1NC15481172cSize': [4305], 'sequencing.tsp-1': [4311], 'homology4NC1NC1751800dSize': [4312], 'mapping.,eSize': [4319, 4340, 4365, 4390], 'PCR.tsp-1': [4325], 'homology5NC1NC1817500dSize': [4326], 'mapping.6NC1NC11483900dSize': [4333], 'PCR.7NC1NC11132500eSize': [4346], 'PCR.8NC1NC11351400eSize': [4352], 'PCR.9NC1NC115313,600dSize': [4358], 'PCR.10NC1NC1150408cSize': [4371], 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'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-14T07:32:31.335002', 'created_date': '2016-06-24'}