Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1974684692', 'doi': 'https://doi.org/10.1210/endo.141.3.7370', 'title': 'Impaired Basal and Restraint-Induced Epinephrine Secretion in Corticotropin-Releasing Hormone- Deficient Mice<sup>1</sup>', 'display_name': 'Impaired Basal and Restraint-Induced Epinephrine Secretion in Corticotropin-Releasing Hormone- Deficient Mice<sup>1</sup>', 'publication_year': 2000, 'publication_date': '2000-03-01', 'ids': {'openalex': 'https://openalex.org/W1974684692', 'doi': 'https://doi.org/10.1210/endo.141.3.7370', 'mag': '1974684692', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10698191'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1210/endo.141.3.7370', 'pdf_url': 'https://academic.oup.com/endo/article-pdf/141/3/1142/10360001/endo1142.pdf', 'source': {'id': 'https://openalex.org/S157527038', 'display_name': 'Endocrinology', 'issn_l': '0013-7227', 'issn': ['0013-7227', '1945-7170'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://academic.oup.com/endo/article-pdf/141/3/1142/10360001/endo1142.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5102145399', 'display_name': 'Kyeong‐Hoon Jeong', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1288882113', 'display_name': "Boston Children's Hospital", 'ror': 'https://ror.org/00dvg7y05', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1288882113']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Kyeong-Hoon Jeong', 'raw_affiliation_strings': ['Division of Endocrinology (K.-H.J., L.J., J.A.M.), Children’s Hospital, Harvard Medical School, Boston, Massachusetts 02115'], 'affiliations': [{'raw_affiliation_string': 'Division of Endocrinology (K.-H.J., L.J., J.A.M.), Children’s Hospital, Harvard Medical School, Boston, Massachusetts 02115', 'institution_ids': ['https://openalex.org/I1288882113', 'https://openalex.org/I136199984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064466232', 'display_name': 'Lauren Jacobson', 'orcid': 'https://orcid.org/0000-0002-0406-703X'}, 'institutions': [{'id': 'https://openalex.org/I1288882113', 'display_name': "Boston Children's Hospital", 'ror': 'https://ror.org/00dvg7y05', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1288882113']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Lauren Jacobson', 'raw_affiliation_strings': ['Division of Endocrinology (K.-H.J., L.J., J.A.M.), Children’s Hospital, Harvard Medical School, Boston, Massachusetts 02115'], 'affiliations': [{'raw_affiliation_string': 'Division of Endocrinology (K.-H.J., L.J., J.A.M.), Children’s Hospital, Harvard Medical School, Boston, Massachusetts 02115', 'institution_ids': ['https://openalex.org/I1288882113', 'https://openalex.org/I136199984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068457694', 'display_name': 'Karel Pacák', 'orcid': 'https://orcid.org/0000-0002-3541-3767'}, 'institutions': [{'id': 'https://openalex.org/I4210144228', 'display_name': 'Eunice Kennedy Shriver National Institute of Child Health and Human Development', 'ror': 'https://ror.org/04byxyr05', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210144228']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}, {'id': 'https://openalex.org/I4210110767', 'display_name': 'National Institute of Neurological Disorders and Stroke', 'ror': 'https://ror.org/01s5ya894', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210110767']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Karel Pacák', 'raw_affiliation_strings': ['Clinical Neuroscience Branch, NINDS (K.P., D.S.G.) NIH, Bethesda, Maryland 20892', 'Developmental Endocrinology Branch, NICHD (K.P.), NIH, Bethesda, Maryland 20892'], 'affiliations': [{'raw_affiliation_string': 'Developmental Endocrinology Branch, NICHD (K.P.), NIH, Bethesda, Maryland 20892', 'institution_ids': ['https://openalex.org/I4210144228']}, {'raw_affiliation_string': 'Clinical Neuroscience Branch, NINDS (K.P., D.S.G.) NIH, Bethesda, Maryland 20892', 'institution_ids': ['https://openalex.org/I1299303238', 'https://openalex.org/I4210110767']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5009185203', 'display_name': 'Eric P. Widmaier', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Eric P. Widmaier', 'raw_affiliation_strings': ['Department of Biology (E.P.W.), Boston University, Boston, Massachusetts 02215'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology (E.P.W.), Boston University, Boston, Massachusetts 02215', 'institution_ids': ['https://openalex.org/I111088046']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050003203', 'display_name': 'David S. Goldstein', 'orcid': 'https://orcid.org/0000-0002-5709-9940'}, 'institutions': [{'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}, {'id': 'https://openalex.org/I4210110767', 'display_name': 'National Institute of Neurological Disorders and Stroke', 'ror': 'https://ror.org/01s5ya894', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210110767']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'David S. Goldstein', 'raw_affiliation_strings': ['Clinical Neuroscience Branch, NINDS (K.P., D.S.G.) NIH, Bethesda, Maryland 20892'], 'affiliations': [{'raw_affiliation_string': 'Clinical Neuroscience Branch, NINDS (K.P., D.S.G.) NIH, Bethesda, Maryland 20892', 'institution_ids': ['https://openalex.org/I1299303238', 'https://openalex.org/I4210110767']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5078650087', 'display_name': 'Joseph A. Majzoub', 'orcid': 'https://orcid.org/0000-0002-4983-5143'}, 'institutions': [{'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}, {'id': 'https://openalex.org/I1288882113', 'display_name': "Boston Children's Hospital", 'ror': 'https://ror.org/00dvg7y05', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1288882113']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Joseph A. Majzoub', 'raw_affiliation_strings': ['Division of Endocrinology (K.-H.J., L.J., J.A.M.), Children’s Hospital, Harvard Medical School, Boston, Massachusetts 02115'], 'affiliations': [{'raw_affiliation_string': 'Division of Endocrinology (K.-H.J., L.J., J.A.M.), Children’s Hospital, Harvard Medical School, Boston, Massachusetts 02115', 'institution_ids': ['https://openalex.org/I136199984', 'https://openalex.org/I1288882113']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 6, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3400, 'currency': 'USD', 'value_usd': 3400, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.184, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 81, 'citation_normalized_percentile': {'value': 0.879121, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '141', 'issue': '3', 'first_page': '1142', 'last_page': '1150'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10529', 'display_name': 'Effects of Stress on Brain Function and Health', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2802', 'display_name': 'Behavioral Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10529', 'display_name': 'Effects of Stress on Brain Function and Health', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2802', 'display_name': 'Behavioral Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11839', 'display_name': 'Management of Primary Aldosteronism', 'score': 0.9958, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12421', 'display_name': 'Diagnosis and Management of Adrenal Insufficiency', 'score': 0.9942, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/corticosterone', 'display_name': 'Corticosterone', 'score': 0.8745325}, {'id': 'https://openalex.org/keywords/corticotropin-releasing-hormone', 'display_name': 'Corticotropin-releasing hormone', 'score': 0.64554703}, {'id': 'https://openalex.org/keywords/basal', 'display_name': 'Basal (medicine)', 'score': 0.5686369}, {'id': 'https://openalex.org/keywords/phenylethanolamine-n-methyltransferase', 'display_name': 'Phenylethanolamine N-methyltransferase', 'score': 0.5441897}, {'id': 'https://openalex.org/keywords/stress', 'display_name': 'Stress', 'score': 0.513333}], 'concepts': [{'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.9356983}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.9329028}, {'id': 'https://openalex.org/C2780352252', 'wikidata': 'https://www.wikidata.org/wiki/Q422543', 'display_name': 'Corticosterone', 'level': 3, 'score': 0.8745325}, {'id': 'https://openalex.org/C2776804559', 'wikidata': 'https://www.wikidata.org/wiki/Q7181429', 'display_name': 'Phenylethanolamine', 'level': 4, 'score': 0.85663104}, {'id': 'https://openalex.org/C2775859304', 'wikidata': 'https://www.wikidata.org/wiki/Q132621', 'display_name': 'Epinephrine', 'level': 2, 'score': 0.83457804}, {'id': 'https://openalex.org/C2778458438', 'wikidata': 'https://www.wikidata.org/wiki/Q386664', 'display_name': 'Corticotropin-releasing hormone', 'level': 3, 'score': 0.64554703}, {'id': 'https://openalex.org/C2780841215', 'wikidata': 'https://www.wikidata.org/wiki/Q422549', 'display_name': 'Glucocorticoid', 'level': 2, 'score': 0.6133636}, {'id': 'https://openalex.org/C2778024521', 'wikidata': 'https://www.wikidata.org/wiki/Q55639806', 'display_name': 'Basal (medicine)', 'level': 3, 'score': 0.5686369}, {'id': 'https://openalex.org/C2779546955', 'wikidata': 'https://www.wikidata.org/wiki/Q411541', 'display_name': 'Phenylethanolamine N-methyltransferase', 'level': 5, 'score': 0.5441897}, {'id': 'https://openalex.org/C2780087391', 'wikidata': 'https://www.wikidata.org/wiki/Q366774', 'display_name': 'Adrenalectomy', 'level': 2, 'score': 0.520095}, {'id': 'https://openalex.org/C2778514916', 'wikidata': 'https://www.wikidata.org/wiki/Q186242', 'display_name': 'Norepinephrine', 'level': 3, 'score': 0.50299305}, {'id': 'https://openalex.org/C2775894120', 'wikidata': 'https://www.wikidata.org/wiki/Q271663', 'display_name': 'Catecholamine', 'level': 2, 'score': 0.46501118}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.4436501}, {'id': 'https://openalex.org/C2780694816', 'wikidata': 'https://www.wikidata.org/wiki/Q712294', 'display_name': 'Adrenal gland', 'level': 2, 'score': 0.42183393}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.37327927}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.35489473}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.22367254}, {'id': 'https://openalex.org/C513476851', 'wikidata': 'https://www.wikidata.org/wiki/Q170304', 'display_name': 'Dopamine', 'level': 2, 'score': 0.07786402}, {'id': 'https://openalex.org/C159167319', 'wikidata': 'https://www.wikidata.org/wiki/Q420766', 'display_name': 'Tyrosine hydroxylase', 'level': 3, 'score': 0.055777073}, {'id': 'https://openalex.org/C2779306644', 'wikidata': 'https://www.wikidata.org/wiki/Q2002370', 'display_name': 'Insulin', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D003346', 'descriptor_name': 'Corticotropin-Releasing Hormone', 'qualifier_ui': 'Q000172', 'qualifier_name': 'deficiency', 'is_major_topic': True}, {'descriptor_ui': 'D004837', 'descriptor_name': 'Epinephrine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D013315', 'descriptor_name': 'Stress, Psychological', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000315', 'descriptor_name': 'Adrenalectomy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003345', 'descriptor_name': 'Corticosterone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003345', 'descriptor_name': 'Corticosterone', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D003346', 'descriptor_name': 'Corticotropin-Releasing Hormone', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D003346', 'descriptor_name': 'Corticotropin-Releasing Hormone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004837', 'descriptor_name': 'Epinephrine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005938', 'descriptor_name': 'Glucocorticoids', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D005938', 'descriptor_name': 'Glucocorticoids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017403', 'descriptor_name': 'In Situ Hybridization', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018345', 'descriptor_name': 'Mice, Knockout', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012149', 'descriptor_name': 'Restraint, Physical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020133', 'descriptor_name': 'Reverse Transcriptase Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013315', 'descriptor_name': 'Stress, Psychological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014446', 'descriptor_name': 'Tyrosine 3-Monooxygenase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014446', 'descriptor_name': 'Tyrosine 3-Monooxygenase', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1210/endo.141.3.7370', 'pdf_url': 'https://academic.oup.com/endo/article-pdf/141/3/1142/10360001/endo1142.pdf', 'source': {'id': 'https://openalex.org/S157527038', 'display_name': 'Endocrinology', 'issn_l': '0013-7227', 'issn': ['0013-7227', '1945-7170'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10698191', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1210/endo.141.3.7370', 'pdf_url': 'https://academic.oup.com/endo/article-pdf/141/3/1142/10360001/endo1142.pdf', 'source': {'id': 'https://openalex.org/S157527038', 'display_name': 'Endocrinology', 'issn_l': '0013-7227', 'issn': ['0013-7227', '1945-7170'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.54, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 58, 'referenced_works': ['https://openalex.org/W12760168', 'https://openalex.org/W1498494065', 'https://openalex.org/W1510622602', 'https://openalex.org/W1520452801', 'https://openalex.org/W1523374635', 'https://openalex.org/W1567708878', 'https://openalex.org/W1639792556', 'https://openalex.org/W1969936500', 'https://openalex.org/W1970278879', 'https://openalex.org/W1975877020', 'https://openalex.org/W1976027570', 'https://openalex.org/W1984226490', 'https://openalex.org/W1987054100', 'https://openalex.org/W1991387474', 'https://openalex.org/W1992866860', 'https://openalex.org/W1995690478', 'https://openalex.org/W2000185732', 'https://openalex.org/W2000557149', 'https://openalex.org/W2000776761', 'https://openalex.org/W2014463526', 'https://openalex.org/W2016189310', 'https://openalex.org/W2018919319', 'https://openalex.org/W2019936584', 'https://openalex.org/W2021537415', 'https://openalex.org/W2023023053', 'https://openalex.org/W2033283596', 'https://openalex.org/W2033579793', 'https://openalex.org/W2036535017', 'https://openalex.org/W2041564029', 'https://openalex.org/W2049260006', 'https://openalex.org/W2053705033', 'https://openalex.org/W2054936003', 'https://openalex.org/W2055447689', 'https://openalex.org/W2056587633', 'https://openalex.org/W2060626931', 'https://openalex.org/W2066116223', 'https://openalex.org/W2066990412', 'https://openalex.org/W2067761581', 'https://openalex.org/W2068310585', 'https://openalex.org/W2071059100', 'https://openalex.org/W2081903156', 'https://openalex.org/W2083517874', 'https://openalex.org/W2083849493', 'https://openalex.org/W2086593370', 'https://openalex.org/W2088054370', 'https://openalex.org/W2089368215', 'https://openalex.org/W2090706970', 'https://openalex.org/W2101752127', 'https://openalex.org/W2117252019', 'https://openalex.org/W2118406111', 'https://openalex.org/W2158457036', 'https://openalex.org/W2159417822', 'https://openalex.org/W2162967457', 'https://openalex.org/W2168680964', 'https://openalex.org/W2232896560', 'https://openalex.org/W2265137259', 'https://openalex.org/W2301236204', 'https://openalex.org/W3147343774'], 'related_works': ['https://openalex.org/W2535284031', 'https://openalex.org/W2516701513', 'https://openalex.org/W2493866067', 'https://openalex.org/W2065369794', 'https://openalex.org/W2041626287', 'https://openalex.org/W2038784888', 'https://openalex.org/W2019363320', 'https://openalex.org/W1987593606', 'https://openalex.org/W1972377663', 'https://openalex.org/W1762664047'], 'abstract_inverted_index': {'CRH': [0, 22, 74, 84, 97, 125, 154, 187], 'is': [1], 'thought': [2], 'to': [3, 39, 81, 88, 129, 191], 'play': [4], 'a': [5], 'role': [6, 20], 'in': [7, 23, 68, 73, 83, 94, 124, 134, 144, 153, 167, 186], 'responses': [8], 'of': [9, 21, 26, 61, 140, 175], 'the': [10, 19, 138], 'adrenocortical': [11], 'and': [12, 28, 34, 41, 47, 54, 57, 105, 113, 163, 194, 198, 203], 'adrenomedullary': [13], 'systems': [14], 'during': [15, 58, 117], 'stress.': [16], 'To': [17], 'investigate': [18], 'stress-induced': [24], 'secretions': [25], 'corticosterone': [27, 64, 78, 161], 'epinephrine,': [29], 'we': [30], 'subjected': [31], 'wild-type': [32], '(WT)': [33], 'CRH-deficient': [35], '(knockout,': [36], 'KO)': [37], 'mice': [38, 99, 110, 127, 189], 'restraint,': [40], 'analyzed': [42], 'plasma': [43, 45, 103, 196], 'corticosterone,': [44], 'catecholamines,': [46], 'adrenal': [48, 199], 'phenylethanolamine': [49], 'N-methyltransferase': [50], '(PNMT)': [51], 'gene': [52, 165, 179, 201], 'expression': [53, 166, 202], 'activity': [55, 149], 'before': [56], '3': [59], 'h': [60], 'restraint.': [62, 118], 'Plasma': [63], 'increased': [65], 'over': [66], '40-fold': [67], 'WT': [69, 95, 109, 135, 168], 'mice,': [70, 86, 136, 169], 'but': [71], 'minimally': [72], 'KO': [75, 85, 98, 126, 155, 188], 'mice.': [76, 96, 156], 'Adrenal': [77, 119], 'content': [79, 123], 'tended': [80, 128], 'increase': [82], 'although': [87], 'levels': [89], '5-fold': [90], 'lower': [91, 102, 131, 152], 'than': [92, 108, 132], 'that': [93, 133, 183], 'had': [100], 'significantly': [101, 151], 'epinephrine': [104, 115, 197], 'higher': [106], 'norepinephrine': [107], 'at': [111], 'baseline,': [112], 'delayed': [114], 'secretion': [116, 162], 'PNMT': [120, 147, 164, 178, 200], 'messenger': [121], 'RNA': [122], 'be': [130], 'though': [137], 'degree': [139], 'induction': [141], 'was': [142, 150], 'similar': [143], 'both': [145], 'genotypes.': [146], 'enzyme': [148, 204], 'Pharmacological': [157], 'adrenalectomy': [158], 'abolished': [159], 'restraint-induced': [160, 195], 'consistent': [170], 'with': [171], 'an': [172], 'absolute': [173], 'requirement': [174], 'glucocorticoids': [176], 'for': [177], 'expression.': [180], 'We': [181], 'conclude': [182], 'glucocorticoid': [184], 'insufficiency': [185], 'leads': [190], 'decreased': [192], 'basal': [193], 'activity.': [205]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1974684692', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 7}], 'updated_date': '2024-08-31T14:57:01.623876', 'created_date': '2016-06-24'}