Publication Information

{'id': 'https://openalex.org/W1974048771', 'doi': 'https://doi.org/10.1002/jcb.21630', 'title': 'Constitutive regulation of <i>CYP1B1</i> by the aryl hydrocarbon receptor (AhR) in pre‐malignant and malignant mammary tissue', 'display_name': 'Constitutive regulation of <i>CYP1B1</i> by the aryl hydrocarbon receptor (AhR) in pre‐malignant and malignant mammary tissue', 'publication_year': 2007, 'publication_date': '2007-12-04', 'ids': {'openalex': 'https://openalex.org/W1974048771', 'doi': 'https://doi.org/10.1002/jcb.21630', 'mag': '1974048771', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/18059014'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/jcb.21630', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S53807158', 'display_name': 'Journal of Cellular Biochemistry', 'issn_l': '0730-2312', 'issn': ['0730-2312', '1097-4644'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100510797', 'display_name': 'Xinhai Yang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Xinhai Yang', 'raw_affiliation_strings': ['Department of Environmental Health, Boston University School of Public Health, Boston Massachusetts, 02118, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Environmental Health, Boston University School of Public Health, Boston Massachusetts, 02118, USA', 'institution_ids': ['https://openalex.org/I111088046']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023738167', 'display_name': 'Sandra E. Solomon', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sandra Solomon', 'raw_affiliation_strings': ['Department of Environmental Health Boston University School of Public Health Boston Massachusetts'], 'affiliations': [{'raw_affiliation_string': 'Department of Environmental Health Boston University School of Public Health Boston Massachusetts', 'institution_ids': ['https://openalex.org/I111088046']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090331481', 'display_name': 'Lauren R. Fraser', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I86115722', 'display_name': 'Furman University', 'ror': 'https://ror.org/04ytb9n23', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I86115722']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Lauren R. Fraser', 'raw_affiliation_strings': ['Biology Department, Furman University, Greenville, South Carolina'], 'affiliations': [{'raw_affiliation_string': 'Biology Department, Furman University, Greenville, South Carolina', 'institution_ids': ['https://openalex.org/I86115722']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018404646', 'display_name': 'Anthony F. Trombino', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Anthony F. Trombino', 'raw_affiliation_strings': ['Department of Environmental Health Boston University School of Public Health Boston Massachusetts'], 'affiliations': [{'raw_affiliation_string': 'Department of Environmental Health Boston University School of Public Health Boston Massachusetts', 'institution_ids': ['https://openalex.org/I111088046']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100599979', 'display_name': 'Donghui Liu', 'orcid': 'https://orcid.org/0000-0002-7121-2364'}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Donghui Liu', 'raw_affiliation_strings': ['Department of Environmental Health Boston University School of Public Health Boston Massachusetts'], 'affiliations': [{'raw_affiliation_string': 'Department of Environmental Health Boston University School of Public Health Boston Massachusetts', 'institution_ids': ['https://openalex.org/I111088046']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079640868', 'display_name': 'Gail E. Sonenshein', 'orcid': 'https://orcid.org/0000-0002-5959-9922'}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Gail E. Sonenshein', 'raw_affiliation_strings': ['Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts;'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts;', 'institution_ids': ['https://openalex.org/I111088046']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028936407', 'display_name': 'Eli V. Hestermann', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I86115722', 'display_name': 'Furman University', 'ror': 'https://ror.org/04ytb9n23', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I86115722']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Eli V. Hestermann', 'raw_affiliation_strings': ['Biology Department, Furman University, Greenville, South Carolina'], 'affiliations': [{'raw_affiliation_string': 'Biology Department, Furman University, Greenville, South Carolina', 'institution_ids': ['https://openalex.org/I86115722']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5067639617', 'display_name': 'David H. Sherr', 'orcid': 'https://orcid.org/0000-0003-3353-0553'}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'David H. Sherr', 'raw_affiliation_strings': ['Boston University Medical Campus Flow Cytometry Core, Boston, Massachusetts', 'Department of Environmental Health, Boston University School of Public Health, Boston, Massachusetts'], 'affiliations': [{'raw_affiliation_string': 'Boston University Medical Campus Flow Cytometry Core, Boston, Massachusetts', 'institution_ids': ['https://openalex.org/I111088046']}, {'raw_affiliation_string': 'Department of Environmental Health, Boston University School of Public Health, Boston, Massachusetts', 'institution_ids': ['https://openalex.org/I111088046']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4640, 'currency': 'USD', 'value_usd': 4640, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.418, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 113, 'citation_normalized_percentile': {'value': 0.915792, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '104', 'issue': '2', 'first_page': '402', 'last_page': '417'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10122', 'display_name': 'Toxic Organic Pollutants Impact', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2307', 'display_name': 'Health, Toxicology and Mutagenesis'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10122', 'display_name': 'Toxic Organic Pollutants Impact', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2307', 'display_name': 'Health, Toxicology and Mutagenesis'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10686', 'display_name': 'Effects and risks of endocrine disrupting chemicals', 'score': 0.9958, 'subfield': {'id': 'https://openalex.org/subfields/2307', 'display_name': 'Health, Toxicology and Mutagenesis'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10433', 'display_name': 'Carcinogens and Genotoxicity Assessment', 'score': 0.9922, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cyp1b1', 'display_name': 'CYP1B1', 'score': 0.9674625}], 'concepts': [{'id': 'https://openalex.org/C33594762', 'wikidata': 'https://www.wikidata.org/wiki/Q155750', 'display_name': 'Aryl hydrocarbon receptor', 'level': 4, 'score': 0.98794615}, {'id': 'https://openalex.org/C155701950', 'wikidata': 'https://www.wikidata.org/wiki/Q14905165', 'display_name': 'CYP1B1', 'level': 4, 'score': 0.9674625}, {'id': 'https://openalex.org/C555283112', 'wikidata': 'https://www.wikidata.org/wiki/Q1637543', 'display_name': 'Carcinogenesis', 'level': 3, 'score': 0.6721569}, {'id': 'https://openalex.org/C173396325', 'wikidata': 'https://www.wikidata.org/wiki/Q1501275', 'display_name': 'Gene knockdown', 'level': 3, 'score': 0.5811211}, {'id': 'https://openalex.org/C45815257', 'wikidata': 'https://www.wikidata.org/wiki/Q109984923', 'display_name': 'Aryl hydrocarbon receptor nuclear translocator', 'level': 5, 'score': 0.57922494}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5586901}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.55673754}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.5229312}, {'id': 'https://openalex.org/C526171541', 'wikidata': 'https://www.wikidata.org/wiki/Q407693', 'display_name': 'Cytochrome P450', 'level': 3, 'score': 0.418589}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.36892247}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.3525648}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.2611745}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.17542464}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.10441938}, {'id': 'https://openalex.org/C62231903', 'wikidata': 'https://www.wikidata.org/wiki/Q1057', 'display_name': 'Metabolism', 'level': 2, 'score': 0.06176883}], 'mesh': [{'descriptor_ui': 'D001189', 'descriptor_name': 'Aryl Hydrocarbon Hydroxylases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': True}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D015674', 'descriptor_name': 'Mammary Neoplasms, Animal', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': True}, {'descriptor_ui': 'D018336', 'descriptor_name': 'Receptors, Aryl Hydrocarbon', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001189', 'descriptor_name': 'Aryl Hydrocarbon Hydroxylases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019363', 'descriptor_name': 'Cytochrome P-450 CYP1A1', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D019363', 'descriptor_name': 'Cytochrome P-450 CYP1A1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D065633', 'descriptor_name': 'Cytochrome P-450 CYP1B1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015674', 'descriptor_name': 'Mammary Neoplasms, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015674', 'descriptor_name': 'Mammary Neoplasms, Animal', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D011230', 'descriptor_name': 'Precancerous Conditions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011401', 'descriptor_name': 'Promoter Regions, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018336', 'descriptor_name': 'Receptors, Aryl Hydrocarbon', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/jcb.21630', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S53807158', 'display_name': 'Journal of Cellular Biochemistry', 'issn_l': '0730-2312', 'issn': ['0730-2312', '1097-4644'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/18059014', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.41, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 96, 'referenced_works': ['https://openalex.org/W1573746641', 'https://openalex.org/W1576212556', 'https://openalex.org/W1588673533', 'https://openalex.org/W1799356912', 'https://openalex.org/W1838929416', 'https://openalex.org/W1882988491', 'https://openalex.org/W1896854564', 'https://openalex.org/W1904731887', 'https://openalex.org/W1963487709', 'https://openalex.org/W1964422998', 'https://openalex.org/W1966542709', 'https://openalex.org/W1966678244', 'https://openalex.org/W1969120382', 'https://openalex.org/W1969656285', 'https://openalex.org/W1971494855', 'https://openalex.org/W1971772902', 'https://openalex.org/W1975091600', 'https://openalex.org/W1975124499', 'https://openalex.org/W1979697640', 'https://openalex.org/W1983938442', 'https://openalex.org/W1985890847', 'https://openalex.org/W1986193653', 'https://openalex.org/W1988376244', 'https://openalex.org/W1989095073', 'https://openalex.org/W1991662292', 'https://openalex.org/W1992240652', 'https://openalex.org/W2002263141', 'https://openalex.org/W2002276902', 'https://openalex.org/W2002597568', 'https://openalex.org/W2005648074', 'https://openalex.org/W2007601885', 'https://openalex.org/W2008478558', 'https://openalex.org/W2021288128', 'https://openalex.org/W2021592976', 'https://openalex.org/W2029453803', 'https://openalex.org/W2031765358', 'https://openalex.org/W2036486872', 'https://openalex.org/W2038523895', 'https://openalex.org/W2041338854', 'https://openalex.org/W2042933378', 'https://openalex.org/W2043858835', 'https://openalex.org/W2047557681', 'https://openalex.org/W2048801047', 'https://openalex.org/W2049693705', 'https://openalex.org/W2049841855', 'https://openalex.org/W2051036666', 'https://openalex.org/W2052528439', 'https://openalex.org/W2053590454', 'https://openalex.org/W2059382320', 'https://openalex.org/W2066139219', 'https://openalex.org/W2066254714', 'https://openalex.org/W2068756348', 'https://openalex.org/W2075679933', 'https://openalex.org/W2079155133', 'https://openalex.org/W2082809617', 'https://openalex.org/W2087368546', 'https://openalex.org/W2089908339', 'https://openalex.org/W2093460761', 'https://openalex.org/W2097893055', 'https://openalex.org/W2104440905', 'https://openalex.org/W2108893850', 'https://openalex.org/W2111970888', 'https://openalex.org/W2112694333', 'https://openalex.org/W2113916497', 'https://openalex.org/W2122496261', 'https://openalex.org/W2125624761', 'https://openalex.org/W2128583496', 'https://openalex.org/W2128603046', 'https://openalex.org/W2129785265', 'https://openalex.org/W2139727090', 'https://openalex.org/W2140641165', 'https://openalex.org/W2141306531', 'https://openalex.org/W2141821206', 'https://openalex.org/W2142013281', 'https://openalex.org/W2142946059', 'https://openalex.org/W2145525843', 'https://openalex.org/W2146264973', 'https://openalex.org/W2146693228', 'https://openalex.org/W2146909058', 'https://openalex.org/W2149540498', 'https://openalex.org/W2150070004', 'https://openalex.org/W2152914176', 'https://openalex.org/W2156927556', 'https://openalex.org/W2161576610', 'https://openalex.org/W2163275958', 'https://openalex.org/W2165117268', 'https://openalex.org/W2165422066', 'https://openalex.org/W2167464398', 'https://openalex.org/W2168611920', 'https://openalex.org/W2168615808', 'https://openalex.org/W2170264506', 'https://openalex.org/W2171382468', 'https://openalex.org/W2408108886', 'https://openalex.org/W2416977311', 'https://openalex.org/W247535234', 'https://openalex.org/W4249203361'], 'related_works': ['https://openalex.org/W2736074206', 'https://openalex.org/W2552659228', 'https://openalex.org/W2394599053', 'https://openalex.org/W2338836030', 'https://openalex.org/W2145744724', 'https://openalex.org/W2132742700', 'https://openalex.org/W2116231282', 'https://openalex.org/W2087366699', 'https://openalex.org/W2070516547', 'https://openalex.org/W2058859727'], 'abstract_inverted_index': {'Abstract': [0], 'The': [1], 'aryl': [2], 'hydrocarbon': [3], 'receptor': [4], '(AhR)': [5], 'is': [6, 21, 42], 'a': [7, 97, 108, 205], 'receptor/transcription': [8], 'factor': [9], 'which': [10, 20, 28, 122, 128], 'regulates': [11], 'cytochrome': [12], 'P450': [13], '(': [14], 'CYP': [15], ')': [16], 'gene': [17, 232], 'transcription': [18], 'and': [19, 44, 49, 67, 88, 125, 164, 171, 194, 207, 250], 'activated': [22], 'by': [23, 107, 139, 145, 174], 'environmental': [24, 83, 247], 'carcinogens,': [25], 'some': [26], 'of': [27, 60, 65, 100, 141, 151, 184, 224], 'are': [29], 'associated': [30], 'with': [31, 116, 231], 'increased': [32, 211], 'breast': [33], 'cancer': [34], 'risk.': [35], 'Here,': [36], 'we': [37], 'show': [38], 'that': [39, 168, 221, 238], 'the': [40, 78, 216, 222, 253], 'AhR': [41, 63, 76, 87, 124, 142, 146, 149, 159, 177, 189, 241, 254], 'over‐expressed': [43], 'constitutively': [45, 74, 109, 175, 239], 'active': [46, 75, 110, 176, 240], 'in': [47, 96, 203, 215, 255], 'human': [48, 117], 'rodent': [50], 'mammary': [51, 101, 118, 256], 'tumors,': [52], 'suggesting': [53], 'its': [54], 'ongoing': [55], 'contribution': [56], 'to': [57, 71, 161, 191], 'tumorigenesis': [58, 102], 'regardless': [59], 'tumor': [61, 94], 'etiology.': [62], 'regulation': [64, 106, 173], 'CYP1A1': [66, 92, 133, 163, 170, 193, 201], 'CYP1B1': [68, 89, 105, 126, 135, 153, 165, 172, 195, 213], 'was': [69, 114, 137], 'studied': [70], 'determine': [72], 'if': [73], 'effects': [77], 'same': [79], 'transcriptional': [80], 'outcomes': [81, 245], 'as': [82], 'chemical‐activated': [84, 248], 'AhR.': [85, 111, 186], 'Elevated': [86], 'but': [90, 127, 210], 'not': [91, 179, 228], 'before': [93], 'formation': [95], 'rat': [98], 'model': [99], 'suggested': [103], 'differential': [104, 169], 'This': [112], 'hypothesis': [113], 'tested': [115], 'gland': [119], 'cell': [120], 'lines': [121], 'hyper‐express': [123], 'express': [129], 'little': [130], 'or': [131, 144], 'no': [132], '.': [134], 'expression': [136], 'diminished': [138], 'repression': [140], 'activity': [143], 'knockdown,': [147], 'demonstrating': [148, 167, 220], 'control': [150], 'basal': [152], 'levels.': [154, 234], 'ChIP': [155], 'assays': [156], 'demonstrated': [157], 'constitutive': [158], 'binding': [160, 190, 226], 'both': [162, 192, 204], 'promoters,': [166], 'does': [178, 227], 'result': [180], 'from': [181], 'different': [182, 243], 'amounts': [183], 'promoter‐bound': [185], 'While': [187], 'increasing': [188], ',': [196], '2,3,7,8‐tetrachlorodibenzo‐': [197], 'p': [198], '‐dioxin': [199], 'induced': [200], 'mRNA': [202, 214, 233], 'malignant': [206, 217], 'non‐malignant': [208], 'line': [209], 'only': [212], 'line,': [218], 'again': [219], 'level': [223], 'promoter': [225], 'necessarily': [229], 'correlate': [230], 'These': [235], 'studies': [236], 'suggest': [237], 'mediates': [242], 'molecular': [244], 'than': [246], 'AhR,': [249], 'further': [251], 'implicate': [252], 'tumorigenesis.': [257], 'J.': [258], 'Cell.': [259], 'Biochem.': [260], '104:': [261], '402–417,': [262], '2008.': [263], '©': [264], '2007': [265], 'Wiley‐Liss,': [266], 'Inc.': [267]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1974048771', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 6}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 8}, {'year': 2017, 'cited_by_count': 9}, {'year': 2016, 'cited_by_count': 8}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 9}, {'year': 2013, 'cited_by_count': 7}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2024-12-10T04:01:39.113695', 'created_date': '2016-06-24'}