Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1973617893', 'doi': 'https://doi.org/10.1002/cbf.290040111', 'title': 'Role of transferrin in iron transport between maternal and fetal circulations of a perfused lobule of human placenta', 'display_name': 'Role of transferrin in iron transport between maternal and fetal circulations of a perfused lobule of human placenta', 'publication_year': 1986, 'publication_date': '1986-01-01', 'ids': {'openalex': 'https://openalex.org/W1973617893', 'doi': 'https://doi.org/10.1002/cbf.290040111', 'mag': '1973617893', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/3943149'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/cbf.290040111', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S960618578', 'display_name': 'Cell Biochemistry and Function', 'issn_l': '0263-6484', 'issn': ['0263-6484', '1099-0844'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5111900418', 'display_name': 'S.F. Contractor', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2802369498', 'display_name': 'Charing Cross Hospital', 'ror': 'https://ror.org/02gcp3110', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I153355300', 'https://openalex.org/I2802369498']}, {'id': 'https://openalex.org/I2801259928', 'display_name': 'Royal London Hospital', 'ror': 'https://ror.org/019my5047', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I225661044', 'https://openalex.org/I2801259928']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'S. F. Contractor', 'raw_affiliation_strings': ['Department of Obsterics and Gynaecology, Charing Cross and Westminster Medical School, West London Hospital, Hammersmith Road, London W6 7DQ, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Department of Obsterics and Gynaecology, Charing Cross and Westminster Medical School, West London Hospital, Hammersmith Road, London W6 7DQ, U.K.', 'institution_ids': ['https://openalex.org/I2802369498', 'https://openalex.org/I2801259928']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5112133574', 'display_name': 'B.M. Eaton', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2802369498', 'display_name': 'Charing Cross Hospital', 'ror': 'https://ror.org/02gcp3110', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I153355300', 'https://openalex.org/I2802369498']}, {'id': 'https://openalex.org/I2801259928', 'display_name': 'Royal London Hospital', 'ror': 'https://ror.org/019my5047', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I225661044', 'https://openalex.org/I2801259928']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'B. M. Eaton', 'raw_affiliation_strings': ['Department of Obsterics and Gynaecology, Charing Cross and Westminster Medical School, West London Hospital, Hammersmith Road, London W6 7DQ, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Department of Obsterics and Gynaecology, Charing Cross and Westminster Medical School, West London Hospital, Hammersmith Road, London W6 7DQ, U.K.', 'institution_ids': ['https://openalex.org/I2802369498', 'https://openalex.org/I2801259928']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4020, 'currency': 'USD', 'value_usd': 4020, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.663, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 31, 'citation_normalized_percentile': {'value': 0.868994, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '4', 'issue': '1', 'first_page': '69', 'last_page': '74'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10554', 'display_name': 'Hemoglobinopathies and Related Disorders', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10554', 'display_name': 'Hemoglobinopathies and Related Disorders', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10452', 'display_name': 'Iron Metabolism and Disorders', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12068', 'display_name': 'Neonatal Health and Biochemistry', 'score': 0.9979, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/human-placenta', 'display_name': 'Human placenta', 'score': 0.6047762}, {'id': 'https://openalex.org/keywords/fetal-circulation', 'display_name': 'Fetal circulation', 'score': 0.51207286}], 'concepts': [{'id': 'https://openalex.org/C2776953305', 'wikidata': 'https://www.wikidata.org/wiki/Q1212935', 'display_name': 'Placenta', 'level': 4, 'score': 0.7560344}, {'id': 'https://openalex.org/C22814914', 'wikidata': 'https://www.wikidata.org/wiki/Q410473', 'display_name': 'Transferrin', 'level': 2, 'score': 0.72401905}, {'id': 'https://openalex.org/C3018059006', 'wikidata': 'https://www.wikidata.org/wiki/Q1212935', 'display_name': 'Human placenta', 'level': 5, 'score': 0.6047762}, {'id': 'https://openalex.org/C172680121', 'wikidata': 'https://www.wikidata.org/wiki/Q26513', 'display_name': 'Fetus', 'level': 3, 'score': 0.6014239}, {'id': 'https://openalex.org/C2779753670', 'wikidata': 'https://www.wikidata.org/wiki/Q2657962', 'display_name': 'Fetal circulation', 'level': 5, 'score': 0.51207286}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.39103502}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.36400205}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.34906477}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3212701}, {'id': 'https://openalex.org/C2779234561', 'wikidata': 'https://www.wikidata.org/wiki/Q11995', 'display_name': 'Pregnancy', 'level': 2, 'score': 0.32104993}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.31909198}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.21548662}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.058580875}], 'mesh': [{'descriptor_ui': 'D005312', 'descriptor_name': 'Fetal Blood', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D007501', 'descriptor_name': 'Iron', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D008431', 'descriptor_name': 'Maternal-Fetal Exchange', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D010920', 'descriptor_name': 'Placenta', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D014168', 'descriptor_name': 'Transferrin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005312', 'descriptor_name': 'Fetal Blood', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007457', 'descriptor_name': 'Iodine Radioisotopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007501', 'descriptor_name': 'Iron', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007504', 'descriptor_name': 'Iron Radioisotopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010477', 'descriptor_name': 'Perfusion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010920', 'descriptor_name': 'Placenta', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011247', 'descriptor_name': 'Pregnancy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014168', 'descriptor_name': 'Transferrin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/cbf.290040111', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S960618578', 'display_name': 'Cell Biochemistry and Function', 'issn_l': '0263-6484', 'issn': ['0263-6484', '1099-0844'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/3943149', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.59}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 19, 'referenced_works': ['https://openalex.org/W115387169', 'https://openalex.org/W1516708335', 'https://openalex.org/W1995135269', 'https://openalex.org/W1997742146', 'https://openalex.org/W2003371525', 'https://openalex.org/W2006207612', 'https://openalex.org/W2013214156', 'https://openalex.org/W2016713142', 'https://openalex.org/W2054205716', 'https://openalex.org/W2054385006', 'https://openalex.org/W2061195883', 'https://openalex.org/W2078137958', 'https://openalex.org/W2079687293', 'https://openalex.org/W2085507399', 'https://openalex.org/W2110408216', 'https://openalex.org/W2130417463', 'https://openalex.org/W21436401', 'https://openalex.org/W2410384880', 'https://openalex.org/W4388547061'], 'related_works': ['https://openalex.org/W4296025728', 'https://openalex.org/W3208768873', 'https://openalex.org/W271579791', 'https://openalex.org/W2494118434', 'https://openalex.org/W2412883775', 'https://openalex.org/W2389974487', 'https://openalex.org/W2364920504', 'https://openalex.org/W2280877341', 'https://openalex.org/W2170207075', 'https://openalex.org/W2090583597'], 'abstract_inverted_index': {'The': [0, 98], 'transfer': [1, 31, 117, 130, 159], 'of': [2, 10, 15, 32, 40, 64, 100, 112, 128, 137, 160, 171], 'iron': [3, 129, 161], 'between': [4], 'the': [5, 41, 47, 65, 72, 105, 119, 125, 132, 135, 153, 157, 163, 168], 'maternal': [6, 106, 138], 'and': [7, 82, 114], 'fetal': [8, 48, 58], 'circulations': [9], 'an': [11, 88, 92], 'isolated': [12], 'perfused': [13], 'lobule': [14], 'term': [16], 'human': [17], 'placenta': [18], 'was': [19, 28, 44, 69], 'investigated': [20], 'using': [21], '125I-labelled': [22], 'or': [23], '59Fe-labelled': [24], 'diferric': [25], 'transferrin.': [26, 59, 172], 'There': [27], 'negligible': [29], 'transplacental': [30, 158], 'intact': [33], 'transferrin': [34, 140], 'whereas': [35], 'nearly': [36], '4': [37], 'per': [38, 62], 'cent': [39, 63], 'added': [42, 66], '59Fe': [43, 67, 113], 'transferred': [45], 'into': [46], 'circulation': [49, 107], 'after': [50], '2': [51], 'h,': [52], 'where': [53], 'it': [54], 'became': [55], 'associated': [56, 78], 'with': [57, 79], 'Over': [60], '20': [61], 'radioactivity': [68], 'sequestered': [70], 'within': [71], 'placental': [73], 'tissue': [74, 110], 'during': [75], 'this': [76], 'period,': [77], 'transferrin,': [80], 'ferritin': [81], 'other': [83], 'uncharacterized': [84], 'molecules.': [85], 'This': [86], 'suggests': [87], 'important': [89], 'role': [90], 'for': [91], 'intracellular': [93], 'pool': [94], 'in': [95, 104], 'regulating': [96], 'transfer.': [97], 'presence': [99], '10': [101], 'mM': [102], 'chloroquine': [103], 'substantially': [108], 'reduced': [109], 'accumulation': [111], 'totally': [115], 'inhibited': [116, 151], 'to': [118, 131, 142, 162], 'fetus.': [120], 'It': [121], 'is': [122], 'concluded': [123], 'that': [124], 'initial': [126], 'stages': [127], 'fetus': [133, 164], 'involve': [134, 167], 'internalization': [136], 'iron-saturated': [139], 'bound': [141], 'membrane': [143], 'receptors': [144], 'by': [145, 152], 'receptor-mediated': [146], 'endocytosis,': [147], 'which': [148], 'can': [149], 'be': [150], 'drug': [154], 'chloroquine.': [155], 'Subsequently,': [156], 'does': [165], 'not': [166], 'concomitant': [169], 'movement': [170]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1973617893', 'counts_by_year': [{'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2025-01-08T23:11:02.508916', 'created_date': '2016-06-24'}