Publication Information

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1848, 1916, 1927, 1932, 1994, 2076, 2191, 2469, 2482, 2595, 2690, 2722, 2729, 2738, 2748, 2771, 2779, 2787, 2799, 2848, 2883, 2897, 2905, 3092, 3251, 3266, 3281, 3334, 3376, 3435, 3454, 3465, 3475, 3512, 3558, 3602, 3690, 3699, 3722, 3944, 3968, 3992, 4027, 4088, 4097, 4130, 4141, 4197, 4299, 4323, 4405], 'the': [3, 22, 67, 90, 128, 154, 173, 218, 241, 279, 393, 649, 654, 707, 819, 827, 885, 935, 940, 949, 988, 1018, 1144, 1235, 1241, 1398, 1575, 1886, 1889, 1906, 1935, 2008, 2043, 2048, 2064, 2073, 2117, 2252, 2265, 2297, 2387, 2427, 2470, 2593, 2596, 2602, 2676, 2681, 2691, 2739, 2758, 2769, 2780, 2796, 2803, 2870, 2898, 2985, 2991, 3064, 3090, 3213, 3248, 3278, 3302, 3313, 3316, 3338, 3341, 3353, 3379, 3473, 3476, 3681, 3852, 3878, 3889, 3921, 3942, 3963, 3988, 4025, 4054, 4086, 4094, 4124, 4138, 4144, 4163, 4194, 4205, 4297, 4319, 4392, 4403], 'adaptor': [4, 155, 655, 1251, 3736], 'protein': [5, 15, 77, 140, 156, 166, 228, 291, 516, 524, 527, 656, 659, 726, 731, 743, 749, 1011, 1049, 1252, 1256, 1265, 2600, 2673, 2694, 2743, 2772, 3565, 3737], 'APPL1': [6, 47, 157, 198, 657, 712, 1949, 2473, 2684, 2702, 3738, 3786, 3893, 3901, 3912, 3945, 3959, 3969, 3993, 4006, 4014, 4064, 4089, 4117, 4147, 4169, 4177, 4201, 4306, 4334], 'to': [7, 111, 158, 262, 716, 939, 1240, 1267, 1387, 1888, 1892, 2238, 3079, 3144, 3306, 3315, 3331, 3340, 3372, 3447, 3692, 4068, 4082, 4090, 4109, 4122, 4178, 4207, 4387, 4396, 4429], 'adiponectin': [8, 35, 49, 55, 108, 159, 186, 200, 206, 259, 389, 397, 714, 1860, 1879, 2192, 2486, 2568, 3307, 3328, 3356, 3370, 3407, 3684, 3729, 3926, 3939, 4066, 4110, 4142, 4166, 4191, 4280, 4292, 4324, 4384, 4425], 'receptors': [9, 56, 160, 207], 'is': [10, 109, 161, 260, 318, 746, 799, 822, 879, 888, 993, 1013, 1052, 1231, 1238, 1453, 1802, 1807, 1842, 2385, 2851, 2866, 2889, 3247, 3255, 3350, 3404, 3592, 3677, 3739, 3871, 3970], 'necessary': [11, 162], 'for': [12, 163, 323, 2293, 2382, 2416, 2536, 2577, 2661, 2669, 2699, 2714, 2768, 2792, 3045, 3106, 3184, 3209, 3231, 3442, 3538, 3594, 3741, 4409], 'adiponectin-induced': [13, 164, 1391], 'AMP-activated': [14, 165, 515, 725], 'kinase': [16, 65, 75, 78, 79, 141, 167, 216, 226, 229, 230, 292, 517, 528, 727, 732, 733, 750, 1050, 1147, 1456], '(AMPK)': [17, 168, 518], 'activation': [18, 40, 169, 191, 718, 924, 956, 1392, 1847, 1915, 1931, 1940, 3426, 3444, 3458, 3744], 'in': [19, 32, 66, 98, 105, 170, 183, 217, 249, 256, 307, 510, 761, 869, 881, 890, 931, 948, 954, 990, 1016, 1055, 1234, 1395, 1585, 1853, 1864, 1876, 1914, 1941, 2195, 2264, 2310, 2417, 2422, 2476, 2479, 2539, 2571, 2589, 2607, 2675, 2742, 2774, 2807, 2863, 2869, 2921, 2932, 3058, 3115, 3157, 3271, 3283, 3301, 3318, 3352, 3408, 3445, 3459, 3486, 3518, 3613, 3680, 3707, 3732, 3745, 3790, 3800, 3851, 3863, 3877, 3905, 3917, 3933, 3960, 3972, 4132, 4184, 4204, 4221, 4318, 4337, 4391], 'muscle,': [20, 171], 'yet': [21, 172], 'underlying': [23, 174, 708, 1399, 1937], 'molecular': [24, 175, 1400], 'mechanism': [25, 176, 1151, 3400, 3441, 3726, 3890, 4061, 4408], 'remains': [26, 177], 'unknown.': [27, 178], 'Here': [28, 179], 'we': [29, 180, 1873, 3275, 3598, 3795, 3898, 4001, 4084, 4159, 4277, 4415], 'show': [30, 103, 181, 254, 873, 4189, 4309], 'that': [31, 104, 126, 144, 182, 255, 277, 295, 751, 872, 987, 1051, 1844, 1875, 1923, 3422, 3432, 3718, 3876, 3910, 3954, 3987, 4053, 4105, 4116, 4137, 4165, 4190, 4291, 4331], 'muscle': [33, 106, 184, 257, 511, 1396, 1590, 1854, 1865, 1877, 1942, 2484, 2524, 2559, 2584, 3733, 3746, 3936], 'cells': [34, 107, 185, 258, 512, 763, 871, 1866, 1878, 2307, 2424, 2862, 2875, 2934, 2978, 3065, 3154, 3202, 3214, 3513, 3747, 3881, 3937, 4222, 4339], 'and': [36, 57, 84, 133, 187, 208, 235, 284, 313, 316, 404, 507, 667, 719, 767, 806, 812, 825, 866, 893, 952, 1007, 1254, 1390, 1463, 1564, 1580, 1806, 1858, 1929, 2005, 2072, 2116, 2259, 2305, 2420, 2474, 2534, 2553, 2580, 2654, 2664, 2703, 2719, 2766, 2872, 2935, 3026, 3055, 3110, 3253, 3293, 3325, 3346, 3355, 3378, 3395, 3456, 3563, 3683, 3703, 3803, 3856, 3885, 3902, 3920, 3946, 3962, 4007, 4075, 4093, 4127, 4148, 4199, 4219, 4303, 4305], 'metformin': [37, 188, 3414, 3493, 3550], 'induce': [38, 189, 3688], 'AMPK': [39, 73, 99, 113, 190, 224, 250, 264, 717, 745, 798, 863, 923, 950, 955, 991, 1021, 1146, 1394, 1797, 1849, 1894, 1939, 3273, 3425, 3443, 3457, 3540, 3559, 3564, 3596, 3705, 3731, 3743, 4069, 4343, 4389, 4410, 4427], 'by': [41, 51, 62, 80, 192, 202, 213, 231, 513, 710, 764, 1003, 1010, 1244, 1260, 1567, 1800, 1850, 1900, 1998, 2081, 2491, 2680, 2708, 2726, 2984, 3401, 3406, 3571, 3727, 3891, 3925, 4062, 4153], 'promoting': [42, 193, 4154], 'APPL1-dependent': [43, 194, 1882], 'LKB1': [44, 59, 132, 195, 210, 283, 1006, 1040, 1141, 1230, 1237, 1383, 1467, 1883, 1928, 1995, 2077, 2260, 2475, 2705, 2800, 2850, 2865, 2886, 2915, 3267, 3282, 3297, 3310, 3336, 3392, 3419, 3436, 3455, 3467, 3478, 3516, 3589, 3609, 3723, 3792, 3797, 3846, 3868, 3895, 3903, 3916, 3947, 3955, 3996, 4057, 4077, 4103, 4131, 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225, 1004, 1455], 'Ca2+/calmodulin-dependent': [76, 227, 730], 'activating': [81, 232, 514, 828], 'phospholipase': [82, 138, 233, 289, 728], 'C': [83, 234, 729, 2873, 3345], 'subsequently': [85, 236], 'inducing': [86, 237], 'Ca2+': [87, 146, 238, 297, 1903, 2993, 3146, 3187, 3235], 'release': [88, 147, 239, 298, 1904], 'from': [89, 148, 240, 299, 1885, 2000, 2257, 2270, 2274, 2286, 2525, 2687, 3312, 3337, 3527], 'endoplasmic': [91, 242, 734], 'reticulum,': [92, 243], 'which': [93, 244, 646, 711, 943, 1459, 1909, 2864, 3190, 3402, 3728, 3892, 4063, 4175], 'plays': [94, 245, 1910, 3268, 3787], 'a': [95, 120, 134, 246, 271, 285, 319, 747, 754, 802, 945, 1045, 1246, 1582, 1911, 2001, 2040, 2061, 3029, 3072, 3097, 3185, 3269, 3319, 3332, 3373, 3399, 3417, 3439, 3604, 3725, 3788, 4011, 4016, 4060, 4099, 4215, 4310, 4397, 4430], 'minor': [96, 135, 247, 286, 1912], 'role': [97, 248, 1913, 3270, 3789], 'activation.': [100, 251, 1895, 3541, 4070, 4411], 'Our': [101, 252, 4288], 'results': [102, 253, 953, 1921, 3716, 3930, 4051, 4188], 'able': [110, 261, 4386], 'activate': [112, 263, 4209], 'via': [114, 265, 996, 1001, 1905], 'two': [115, 266, 807, 1559, 1568, 3049], 'distinct': [116, 267, 1569], 'mechanisms': [117, 268, 709, 1401, 1936], 'as': [118, 269, 753, 1044, 1143, 2198, 2389, 2429, 2489, 2746, 2753, 2805, 2853, 2891, 2939, 2990, 2998, 3239, 3553, 4214, 4433], 'follows:': [119, 270], 'major': [121, 272], 'pathway': [122, 136, 273, 287, 1863], '(the': [123, 137, 274, 288], 'APPL1/LKB1-dependent': [124, 275], 'pathway)': [125, 143, 276, 294], 'promotes': [127, 278], 'C/Ca2+/Ca2+/calmodulin-dependent': [139, 290], 'kinase-dependent': [142, 293], 'stimulates': [145, 296, 934, 1861], 'intracellular': [149, 300, 1902], 'stores.': [150, 301], 'Adiponectin,': [302], 'an': [303, 1149, 1263, 1845, 1881, 2696, 3080, 4406], 'adipokine': [304], 'abundantly': [305], 'expressed': [306, 1054, 2931], 'adipose': [308], 'tissue,': [309, 2478], 'exhibits': [310], 'anti-diabetic,': [311], 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'2005;': [359, 1170, 1422, 1486, 1514, 1545], '26:': [360], '439-451Crossref': [361], '(2102)': [364], '3Mao': [367], 'X.': [368, 468, 672, 1954, 2124, 2202, 2315, 2433, 2812, 2943, 3749, 3808, 4346], 'Hong': [369, 483, 687, 1533, 1969, 2139, 2217, 2330, 2448, 2827, 2958, 3764, 3823, 4361], 'J.Y.': [370, 484, 688, 1970, 2140, 2218, 2331, 2449, 2828, 2959, 3765, 3824, 4362], 'Dong': [371, 489, 693, 1975, 2145, 2223, 2336, 2398, 2454, 2833, 2964, 3770, 3829, 4367], 'L.Q.': [372, 490, 694, 1976, 2146, 2159, 2224, 2337, 2350, 2399, 2455, 2834, 2965, 3771, 3830, 4368], 'Mini': [373], 'Med.': [375, 637], '2006;': [377, 494, 698, 1444, 1827, 1980, 2150, 2228, 2341, 2459, 2838, 2969, 3775, 3834, 4372], '6:': [378], '1331-1340Crossref': [379], '(26)': [382], 'Scholar).': [384, 501, 705, 797, 861, 919, 983, 1039, 1133, 1225, 1381, 1451, 1557, 1794, 1839, 1987, 2107, 2187, 2235, 2378, 2412, 2466, 2520, 2845, 2976, 3013, 3671, 3782, 3841, 4049, 4379], 'beneficial': [386], 'effects': [387], 'are': [390, 1867, 1934, 2308, 2425, 2801, 3237, 3298], 'mediated': [391, 1799, 4152], 'through': [392, 926, 1148], 'direct': [394, 4311], 'interaction': [395, 650, 2471, 3922, 3974, 4004, 4055, 4145, 4312], 'its': [399, 1269, 2036, 2057], 'cell': [400, 2255, 2730, 3497], 'surface': [401], 'receptors,': [402], 'AdipoR1': [403, 652], 'AdipoR2': [405], '(4Yamauchi': [406, 535], 'Kamon': [408, 537, 598], 'Ito': [410, 539, 602], 'Y.': [411, 439, 441, 540, 568, 570, 601, 603, 619, 1435, 4030], 'Tsuchida': [412, 541], 'A.': [413, 542, 837, 903, 905, 1059, 1069, 1101, 1155, 1165, 1275, 1296, 1300, 1317, 1340, 1370, 1407, 1417, 1528, 2093, 2502, 3519, 3618, 3628, 3660, 4232], 'Yokomizo': [414, 543], 'Kita': [416, 545, 612], 'Sugiyama': [418, 547], 'Miyagishi': [420, 549], 'Hara': [422, 551], 'K.': [423, 427, 445, 449, 552, 556, 574, 578, 615, 617, 1083, 1114, 1153, 1315, 1405, 1431, 1433, 1530, 1784, 3642], 'Tsunoda': [424, 553], 'Murakami': [426, 555], 'Ohteki': [428, 557], 'Uchida': [430, 559, 606], 'Takekawa': [432, 561], 'Waki': [434, 563, 604], 'H.': [435, 564, 605, 1079, 1592, 1600, 1602, 1617, 1619, 2165, 2356, 2496, 3638], 'Tsuno': [436, 565], 'N.H.': [437, 566], 'Shibata': [438, 567], 'Terauchi': [440, 569], 'Froguel': [442, 571, 620], 'P.': [443, 474, 572, 621, 625, 678, 1077, 1081, 1759, 1960, 2130, 2163, 2208, 2321, 2354, 2439, 2498, 2818, 2949, 3002, 3636, 3640, 3755, 3814, 4352], 'Tobe': [444, 573], 'Koyasu': [446, 575], 'Taira': [448, 577], 'Kitamura': [450, 579], 'Shimizu': [452, 581], 'Nagai': [454, 583, 630], 'R.': [455, 584, 631, 1087, 1532, 1817, 2084, 3646, 4260], 'Kadowaki': [456, 585, 634], 'Nature.': [458, 587, 1104, 3663], '2003;': [459, 588, 1351, 1725, 2405, 4243, 4269], '423:': [460, 589], '762-769Crossref': [461, 590], '(2647)': [464, 593], '5Mao': [467], 'Kikani': [469, 673, 1955, 2125, 2203, 2316, 2394, 2434, 2813, 2944, 3750, 3809, 4347], 'C.K.': [470, 674, 1956, 2126, 2204, 2317, 2395, 2435, 2814, 2945, 3751, 3810, 4348], 'Riojas': [471, 675, 1957, 2127, 2205, 2318, 2436, 2815, 2946, 3752, 3811, 4349], 'R.A.': [472, 676, 1958, 2128, 2206, 2319, 2437, 2816, 2947, 3753, 3812, 4350], 'Langlais': [473, 677, 1959, 2129, 2162, 2207, 2320, 2353, 2438, 2817, 2948, 3754, 3813, 4351], 'Wang': [475, 679, 1961, 2131, 2209, 2322, 2440, 2819, 2950, 3756, 3815, 4353], 'L.': [476, 680, 771, 1475, 1962, 2132, 2169, 2210, 2323, 2360, 2441, 2820, 2951, 3757, 3816, 4258, 4354], 'Ramos': [477, 681, 1963, 2133, 2211, 2324, 2442, 2821, 2952, 3758, 3817, 4355], 'F.J.': [478, 682, 1964, 2134, 2212, 2325, 2443, 2822, 2953, 3759, 3818, 4356], 'Fang': [479, 683, 1965, 2135, 2213, 2326, 2444, 2823, 2954, 3760, 3819, 4357], 'Q.': [480, 684, 1966, 2136, 2214, 2327, 2445, 2824, 2955, 3761, 3820, 4358], 'Christ-Roberts': [481, 685, 1967, 2137, 2215, 2328, 2446, 2825, 2956, 3762, 3821, 4359], 'C.Y.': [482, 686, 1968, 2138, 2216, 2329, 2447, 2826, 2957, 3763, 3822, 4360], 'Kim': [485, 689, 1971, 2141, 2219, 2332, 2450, 2829, 2960, 3766, 3825, 4363], 'R.Y.': [486, 690, 1972, 2142, 2220, 2333, 2451, 2830, 2961, 3767, 3826, 4364], 'Liu': [487, 691, 1973, 2143, 2170, 2221, 2334, 2361, 2452, 2831, 2962, 3768, 3827, 4365], 'F.': [488, 623, 692, 1719, 1974, 2144, 2171, 2222, 2335, 2362, 2453, 2832, 2963, 3769, 3828, 4366], 'Nat.': [491, 636, 695, 1977, 2147, 2225, 2338, 2456, 2835, 2966, 3772, 3831, 4369], 'Cell': [492, 696, 1484, 1543, 1978, 2148, 2226, 2287, 2339, 2457, 2836, 2967, 3773, 3832, 4370], '8:': [495, 639, 699, 1305, 1981, 2151, 2229, 2342, 2460, 2839, 2970, 3776, 3835, 4373], '516-523Crossref': [496, 700, 1982, 2152, 2230, 2343, 2461, 2840, 2971, 3777, 3836, 4374], '(544)': [499, 703, 1985, 2155, 2233, 2346, 2464, 2843, 2974, 3780, 3839, 4377], 'increases': [503, 3236], 'fatty': [504], 'acid': [505, 1577], 'oxidation': [506], 'glucose': [508, 766], 'uptake': [509], '3The': [519], 'abbreviations': [520], 'used': [521, 2263, 2989, 3096, 3143], 'are:': [522], 'AMPKAMP-activated': [523], 'kinasePLCphospholipase': [525], 'CCaMKKCa2+/calmodulin-dependent': [526], 'kinaseERendoplasmic': [529], 'reticulumIP3inositol': [530], 'triphosphateHAhemagglutininGSTglutathione': [531], 'S-transferaseYFPyellow': [532], 'fluorescent': [533, 742, 3030], 'proteinDAPI4′,6-diamidino-2-phenylindole.': [534], '6Yamauchi': [596], 'Minokoshi': [600], 'Yamashita': [608], 'Noda': [610], 'Ueki': [614], 'Eto': [616], 'Akanuma': [618], 'Foufelle': [622], 'Ferre': [624], 'Carling': [626, 842, 906, 1186, 1214, 1541], 'D.': [627, 843, 907, 1061, 1157, 1163, 1187, 1215, 1409, 1415, 1542, 1649, 1823, 3620], 'Kimura': [628], 'Kahn': [632], 'B.B.': [633], '2002;': [638, 1323, 2100], '1288-1295Crossref': [640], '(3460)': [643], 'Scholar),': [645, 2033, 4276], 'depends': [647], 'on': [648, 1810, 2659, 2795, 3020, 3361, 4143, 4284, 4296], '(Adaptor': [658], 'containing': [660, 2543], 'Pleckstrin': [661], 'homology': [662, 1465, 1573], 'domain,': [663, 666], 'Phosphotyrosine': [664], 'Leucine': [668], 'zipper': [669], 'motif)': [670], '(5Mao': [671, 1953, 2123, 2201, 2314, 2432, 2811, 2942, 3748, 3807, 4345], 'However,': [706, 1856, 4000, 4158, 4380], 'other': [720, 2282], 'downstream': [721], 'targets': [722], 'remain': [723, 1402], 'unclear.': [724], 'reticulum': [735], 'inositol': [736], 'triphosphate': [737], 'hemagglutinin': [738, 2044], 'glutathione': [739], 'S-transferase': [740], 'yellow': [741], '4′,6-diamidino-2-phenylindole.': [744], 'serine/threonine': [748, 1048], 'acts': [752, 1142], 'master': [755], 'sensor': [756], 'cellular': [758, 1138, 2383, 2797, 3279, 3798], 'energy': [759, 1139], 'balance': [760], 'mammalian': [762, 870, 2009], 'regulating': [765, 1017], 'lipid': [768], 'metabolism': [769], '(7Hue': [770], 'Rider': [772], 'M.H.': [773], 'Essays': [774], 'Biochem.': [775, 910, 1216, 1440, 2098], '2007;': [776, 790, 1218, 1742, 1769], '43:': [777], '121-137Crossref': [778], '(64)': [781], '8Towler': [784], 'M.C.': [785], 'Hardie': [786, 844, 908, 971, 1117, 1162, 1188, 1414, 1482, 1781], 'D.G.': [787, 845, 909, 970, 972, 1118, 1189, 1483, 1782], 'Circ.': [788], 'Res.': [789, 1442, 1604, 1607, 1721, 1724, 2511], '100:': [791, 2406], '328-341Crossref': [792], '(1063)': [795], 'composed': [800], 'catalytic': [803, 816], 'α': [804], 'subunit': [805, 821, 878, 887], 'noncatalytic': [808], 'regulatory': [809], 'subunits,': [810], 'β': [811], 'γ.': [813], 'NH2-terminal': [815, 3964, 3989], 'domain': [817, 3967, 3991], 'AMPKα': [820], 'highly': [823], 'conserved': [824], 'contains': [826], 'phosphorylation': [829, 1002, 1798, 2720, 2744, 3375, 3381, 3397, 3557, 3706, 4344, 4390, 4428], 'site': [830], '(Thr172)': [831], '(9Hawley': [832], 'S.A.': [833, 901, 960, 1179, 1469], 'Davison': [834], 'Woods': [836, 904], 'Davies': [838], 'S.P.': [839, 1534], 'Beri': [840], 'R.K.': [841], '1996;': [849, 1659], '271:': [850, 1660], '27879-27887Abstract': [851], '(1008)': [859], 'Two': [862], 'variants,': [864], 'α1': [865], 'α2,': [867], 'exist': [868], 'different': [874, 4079], 'patterns.': [876], 'AMPKα1': [877], 'localized': [880, 1233, 2867, 2885, 3299, 3351, 3679, 3850, 4102], 'non-nuclear': [882, 894], 'fractions,': [883], 'whereas': [884], 'AMPKα2': [886, 3349, 3362, 3396, 3403], 'found': [889, 4115, 4330], 'both': [891, 3289, 4123], 'nucleus': [892, 1887, 2871, 3314, 3339], 'fractions': [895], '(10Salt': [896], 'I.': [897, 1063, 3622], 'Celler': [898], 'J.W.': [899, 958], 'Hawley': [900, 959], 'Prescott': [902, 1343, 4235], '1998;': [912, 1105, 1608, 1693, 3664], '334:': [913], '177-187Crossref': [914], '(379)': [917], 'Biochemical': [920], 'regulation': [921], 'occurs': [925], 'mechanisms.': [928], 'An': [929], 'increase': [930, 989, 2741], 'AMP': [932, 938, 1805], 'level': [933, 1579, 3250], 'γ': [941], 'subunit,': [942], 'induces': [944, 1880], 'conformational': [946, 998, 4170], 'change': [947, 2882, 4171], 'heterotrimer': [951], '(11Scott': [957], 'Green': [961, 1158, 1410], 'K.A.': [962, 1159, 1411, 1502, 1645, 1673], 'Anis': [963], 'Stewart': [965], 'Scullion': [967], 'G.A.': [968], 'Norman': [969], 'Clin.': [974], 'Invest.': [975], '2004;': [976, 1126], '113:': [977], '274-284Crossref': [978], '(607)': [981], 'Studies': [984], 'have': [985, 4078], 'shown': [986, 1386, 3517], 'activity': [992, 1019], 'not': [994, 1868, 3229, 3687, 3998, 4021, 4308, 4326], 'solely': [995], 'AMP-dependent': [997, 1150], 'change,': [999], 'rather': [1000], 'kinases,': [1005], 'CaMKK.': [1008], 'Dephosphorylation': [1009], 'phosphatases': [1012], 'important': [1015], '(12Witczak': [1022], 'C.A.': [1023, 1734], 'Sharoff': [1024], 'C.G.': [1025], 'Goodyear': [1026, 1739], 'L.J.': [1027, 1740], 'Cell.': [1028, 2024], 'Mol.': [1029, 1302, 1321, 1372, 1605, 1722, 2023], 'Life': [1030], 'Sci.': [1031, 1281, 2403], '2008;': [1032, 1787, 2513], '65:': [1033], '3737-3755Crossref': [1034], '(179)': [1037], 'has': [1041, 1384, 3358, 4106, 4281], 'been': [1042, 1385], 'considered': [1043], 'constitutively': [1046, 3605, 4100], 'active': [1047], 'ubiquitously': [1053], 'all': [1056], 'tissues': [1057], '(13Hemminki': [1058, 3617], 'Markie': [1060, 3619], 'Tomlinson': [1062, 3621], 'Avizienyte': [1064, 3623], 'E.': [1065, 3624], 'Roth': [1066, 3625], 'Loukola': [1068, 3627], 'Bignell': [1070, 3629], 'Warren': [1072, 3631], 'W.': [1073, 1091, 3632, 3650], 'Aminoff': [1074, 3633], 'Höglund': [1076, 3635], 'Järvinen': [1078, 3637], 'Kristo': [1080, 3639], 'Pelin': [1082, 3641], 'Ridanpää': [1084, 3643], 'Salovaara': [1086, 3645], 'Toro': [1088, 3647], 'Bodmer': [1090, 3649], 'Olschwang': [1092, 3651], 'Olsen': [1094, 3653], 'A.S.': [1095, 3654], 'Stratton': [1096, 3655], 'M.R.': [1097, 3656], 'de': [1098, 3657], 'la': [1099, 3658], 'Chapelle': [1100, 3659], 'Aaltonen': [1102, 3661], 'L.A.': [1103, 1510, 3662], '391:': [1106, 3665], '184-187Crossref': [1107, 3666], '(1351)': [1110, 3669], '14Sakamoto': [1113], 'Göransson': [1115], 'O.': [1116], 'Alessi': [1119, 1166, 1347, 1418, 2085, 2096, 4239, 4263], 'D.R.': [1120, 1167, 1348, 1419, 2097, 4240, 4264], 'Am.': [1121, 1764], 'Physiol.': [1123, 1766, 1786], 'Endocrinol.': [1124, 1767], 'Metab.': [1125, 1485, 1544, 1768, 2510], '287:': [1127], 'E310-E317Crossref': [1128], '(264)': [1131], 'Under': [1134, 1226, 3286, 3842], 'conditions': [1135], 'high': [1137], 'stress,': [1140], 'primary': [1145], '(15Sakamoto': [1152, 1404], 'McCarthy': [1154, 1406], 'Smith': [1156, 1295, 1408], 'Grahame': [1160, 1412], 'F.A.': [1161, 1413], 'Ashworth': [1164, 1299, 1369, 1416], 'EMBO': [1168, 1349, 1420, 4241, 4267], '24:': [1171, 1423, 2514], '1810-1820Crossref': [1172, 1424], '(443)': [1175, 1427], '16Hawley': [1178], 'Selbert': [1180, 1642, 1682], 'M.A.': [1181, 1213, 1643, 1683, 2393], 'Goldstein': [1182, 1650, 1680], 'E.G.': [1183, 1651, 1681], 'Edelman': [1184, 1478, 1684], 'A.M.': [1185, 1479, 1639, 1685], '27186-27191Abstract': [1195], '(365)': [1203], '17Sanders': [1206], 'M.J.': [1207, 2397], 'Grondin': [1208], 'P.O.': [1209], 'Hegarty': [1210], 'B.D.': [1211], 'Snowden': [1212], '403:': [1219], '139-148Crossref': [1220], '(528)': [1223], 'normal': [1227], 'physiological': [1228], 'conditions,': [1229, 3288, 3844], 'predominantly': [1232, 2868, 2877, 3848], 'nucleus.': [1236, 3303], 'translocated': [1239, 3311], 'cytosol,': [1242, 1890, 3354], 'either': [1243, 4314], 'forming': [1245], 'heterotrimeric': [1247], 'complex': [1248, 4017, 4216, 4286], 'Ste20-related': [1250], '(STRADα/β)': [1253], 'mouse': [1255, 2002, 2477, 3934], '25': [1257, 3131], '(MO25α/β)': [1258], 'or': [1259, 2047, 2565, 2732, 3233, 3491, 4172, 4316, 4321], 'associating': [1261], 'LKB1-interacting': [1264], '(LIP1),': [1266], 'exert': [1268], 'biological': [1270], 'function': [1271], '(18Tiainen': [1272], 'Ylikorkala': [1274, 1316], 'Mäkelä': [1276, 1318], 'T.P.': [1277, 1319], 'Proc.': [1278, 2400], 'Natl.': [1279, 2401], 'Acad.': [1280, 2402], 'U.S.A.': [1282, 2404], '1999;': [1283, 1304, 2175, 2366, 4042], '96:': [1284], '9248-9251Crossref': [1285], '(263)': [1288], '19Smith': [1291], 'D.P.': [1292, 1360], 'Spicer': [1293, 1365], 'Swift': [1297], 'Hum.': [1301, 1320, 1371], 'Genet.': [1303, 1322, 1373], '1479-1485Crossref': [1306], '(72)': [1309], '20Tiainen': [1312], 'Vaahtomeri': [1314], '11:': [1324], '1497-1504Crossref': [1325], '(176)': [1328], '21Boudeau': [1331], 'Baas': [1333, 4225], 'A.F.': [1334, 4226, 4252], 'Deak': [1335, 2090, 4227], 'Morrice': [1337, 2094, 4229, 4261], 'N.A.': [1338, 4230, 4262], 'Kieloch': [1339, 2092, 4231], 'Schutkowski': [1341, 4233], 'A.R.': [1344, 1508, 1653, 1689, 4236], 'Clevers': [1345, 4237, 4265], 'H.C.': [1346, 4238, 4266], '22:': [1352, 4244, 4270], '5102-5114Crossref': [1353, 4245], '(356)': [1356, 4248], '22Smith': [1359], 'Rayter': [1361], 'S.I.': [1362], 'Niederlander': [1363], 'C.': [1364], 'Jones': [1367], 'C.M.': [1368], '2001;': [1374], '10:': [1375], '2869-2877Crossref': [1376], '(78)': [1379], 'Although': [1382], 'mediate': [1388], 'contraction-': [1389], 'cells,': [1397, 2296, 2300, 2304, 3153, 3413, 3866, 4394], 'elusive': [1403], '23Imai': [1430], 'Inukai': [1432], 'Ikegami': [1434], 'Awata': [1436], 'Katayama': [1438], 'Biophys.': [1441], 'Commun.': [1443], '351:': [1445], '595-601Crossref': [1446], '(49)': [1449], 'CaMKK': [1452, 1851, 1899, 1933], 'AMPK,': [1458, 4008], 'shows': [1460], 'considerable': [1461], 'sequence': [1462, 1578, 2041, 2062], 'structural': [1464], '(24Hawley': [1468], 'Pan': [1470], 'D.A.': [1471], 'Mustard': [1472, 1779], 'K.J.': [1473, 1780], 'Ross': [1474], 'Bain': [1476], 'Frenguelli': [1480], 'B.G.': [1481], '2:': [1487, 1546], '9-19Abstract': [1488], '(1277)': [1496], '25Hurley': [1499], 'R.L.': [1500, 1675], 'Anderson': [1501, 1644], 'Franzone': [1503], 'J.M.': [1504, 1711], 'Kemp': [1505, 1654, 1678], 'B.E.': [1506, 1655, 1679], 'Means': [1507, 1652, 1674, 1688], 'Witters': [1509], '280:': [1515], '29060-29066Abstract': [1516], '(814)': [1524], '26Woods': [1527], 'Dickerson': [1529], 'Heath': [1531], 'Momcilovic': [1535], 'Johnstone': [1537], 'S.R.': [1538], 'Carlson': [1539], '21-33Abstract': [1547], '(1071)': [1555], 'isoforms': [1560], 'CaMKK,': [1562], 'CaMKKα': [1563], 'CaMKKβ,': [1565], 'encoded': [1566], 'genes,': [1570], 'share': [1571], '∼70%': [1572], 'at': [1574, 2035, 2056, 2574, 2592, 2666, 3042, 3089, 3118, 3258, 3384], 'amino': [1576, 1991], 'exhibit': [1581], 'wide': [1583], 'expression': [1584, 2010, 2718, 2773, 4335], 'rodent': [1586], 'tissues,': [1587], 'including': [1588], 'skeletal': [1589, 2483, 2523, 3935], '(27Sakagami': [1591], 'Saito': [1593], 'Kitani': [1595], 'Okuno': [1597], 'Fujisawa': [1599], 'Kondo': [1601], 'Brain': [1603, 1606, 1720, 1723], '54:': [1609], '311-315Crossref': [1610], '(37)': [1613], '28Tokumitsu': [1616], 'Enslen': [1618], 'Soderling': [1620], 'T.R.': [1621], '19320-19324Abstract': [1627], '(208)': [1635], '29Edelman': [1638], 'Mitchelhill': [1640], 'K.I.': [1641], 'Hook': [1646], 'S.S.': [1647], 'Stapleton': [1648], '10806-10810Abstract': [1661], '(92)': [1669], '30Anderson': [1672], 'Huang': [1676], 'Q.H.': [1677], 'Fremeau': [1686], 'R.T.': [1687], '273:': [1694], '31880-31889Abstract': [1695], '(214)': [1703], '31Vinet': [1706], 'Carra': [1708], 'Blom': [1710], 'Harvey': [1712], 'Brunello': [1714], 'N.': [1715, 1717, 1736, 1757, 2095], 'Barden': [1716], 'Tascedda': [1718], '111:': [1726], '216-221Crossref': [1727], '(25)': [1730], '32Witczak': [1733], 'Fujii': [1735], 'Hirshman': [1737], 'M.F.': [1738], 'Diabetes.': [1741], '56:': [1743], '1403-1409Crossref': [1744], '(97)': [1747], '33Jensen': [1750], 'T.E.': [1751], 'Rose': [1752], 'A.J.': [1753], 'Jørgensen': [1754], 'S.B.': [1755], 'Brandt': [1756], 'Schjerling': [1758], 'Wojtaszewski': [1760], 'J.F.': [1761], 'Richter': [1762], 'E.A.': [1763, 4038], '292:': [1770], 'E1308-E1317Crossref': [1771], '(173)': [1774], '34McGee': [1777], 'S.L.': [1778, 2020], 'Baar': [1783], '586:': [1788], '1731-1741Crossref': [1789], '(83)': [1792], 'Unlike': [1795], 'LKB1,': [1796, 4098], 'CaMKKs': [1801], 'independent': [1803, 3529], 'dependent': [1808], 'only': [1809], 'Ca2+/calmodulin': [1811], '(35Suter': [1812], 'Riek': [1814], 'U.': [1815, 1819], 'Tuerk': [1816], 'Schlattner': [1818], 'Wallimann': [1820], 'Neumann': [1822], '281:': [1828], '32207-32216Abstract': [1829], '(374)': [1837], 'Hence,': [1840], 'it': [1841], 'possible': [1843], 'LKB1-independent': [1846], 'exists': [1852, 4213], 'cells.': [1855, 1943, 3410, 3461, 3734, 3906, 4185, 4419], 'whether': [1857, 3263, 3588, 3785, 4073, 4279], 'how': [1859], 'known.': [1869], 'In': [1870, 2521, 3014, 3304, 3411, 3672, 3696, 3977, 4420], 'study,': [1872], 'demonstrate': [1874, 1922, 3717], 'translocation': [1884, 2798, 3333, 3394, 3421, 3434, 3453, 3591, 3689, 3870], 'leading': [1891], 'increased': [1893], 'stimulating': [1901], 'PLC-dependent': [1907], 'mechanism,': [1908], 'AMPK.': [1917, 4210], 'Taken': [1918, 3713], 'together,': [1919, 3714], 'our': [1920, 2311, 2808, 3982, 4187], 'enhanced': [1924, 3719, 3941], 'Ca2+-induced': [1930], 'adiponectin-stimulated': [1938, 3272, 3595, 3600, 3742, 3791, 3867, 4342], 'cDNAs': [1945], 'encoding': [1946, 1990, 2042, 2063, 2068, 2110], 'full-length': [1947], 'human': [1948], 'was': [1950, 1996, 2193, 2268, 2273, 2487, 2528, 2678, 2685, 2755, 3142, 3177, 3382, 3847, 3923, 4385], 'described': [1951, 2121, 2199, 2309, 2390, 2430, 2490, 2806, 2940, 2999], 'previously': [1952, 2122, 2200, 2391, 2431, 3000, 4329], 'cDNA': [1989, 2003], 'acids': [1992, 2114], '1–427': [1993], 'cloned': [1997, 2920], 'PCR': [1999], 'library': [2004], 'subcloned': [2006], 'into': [2007, 2531], 'vector': [2011, 2923, 2982], 'pBEX1': [2012], '(36Bram': [2013], 'R.J.': [2014], 'Hung': [2015], 'D.T.': [2016], 'Martin': [2017], 'P.K.': [2018], 'Schreiber': [2019], 'Crabtree': [2021], 'G.R.': [2022], '1993;': [2026, 3006], '13:': [2027], '4760-4769Crossref': [2028], '(247)': [2031], 'in-frame': [2034, 2055], 'COOH': [2037, 2058], 'terminus': [2038, 2059], '(HA)': [2045], 'tag,': [2046], 'pcDNA': [2049], '3.1': [2050], 'myc/His': [2051], 'A': [2052, 3324, 3884], 'plasmid': [2053], '(Invitrogen),': [2054], 'Myc': [2065, 2247, 2253, 3484], 'tag.': [2066], 'Plasmids': [2067], 'YFP-fused': [2069], 'wild': [2070, 4091, 4125], 'type': [2071, 4092, 4126], 'SL-26': [2074, 4095, 4128], 'mutant': [2075, 3610, 4104, 4129], 'were': [2078, 2120, 2262, 2284, 2561, 2586, 2605, 2706, 2724, 2782, 2900, 2929, 2988, 2996, 3018, 3066, 3069, 3112, 3155, 3203, 3215, 3221, 3228, 3499, 3547, 3569, 3931], 'kindly': [2079], 'provided': [2080], 'Dr.': [2082], 'Dario': [2083], '(37Sapkota': [2086], 'G.P.': [2087, 4256], 'Boudeau': [2088, 4253], '362:': [2101], '481-490Crossref': [2102], '(79)': [2105], 'plasmids': [2109], 'GST-APPL1': [2111], '(CT)': [2112], '(amino': [2113], '455–693)': [2115], 'anti-APPL1': [2118], 'antibody': [2119, 2697], '38Dong': [2158, 2349], 'Zhang': [2160, 2351], 'R.B.': [2161, 2352], 'He': [2164, 2355], 'Clark': [2166, 2357], 'Zhu': [2168, 2359], '274:': [2176, 2367], '8117-8122Abstract': [2177, 2368], '(89)': [2185, 2376], 'globular': [2189, 2567], 'form': [2190, 4096], 'produced': [2194], 'Escherichia': [2196], 'coli': [2197], 'Monoclonal': [2236], 'antibodies': [2237, 2283, 2713], 'HA': [2239], 'tag': [2240, 2248], '(Covance,': [2241], 'Emeryville,': [2242], 'CA),': [2243], 'β-tubulin': [2244], '2.1': [2245], '(Sigma),': [2246], '(produced': [2249], 'in-house': [2250], '1–9E10.2': [2254], 'clone': [2256], 'ATCC),': [2258], '(Upstate)': [2261], 'experiments.': [2266, 3530], 'STO-609': [2267], 'obtained': [2269, 2285, 3932], 'Sigma;': [2271], 'U73122': [2272, 3208], 'Santa': [2275], 'Cruz': [2276], 'Biotechnology': [2277], '(Santa': [2278], 'Cruz,': [2279], 'CA).': [2280], 'All': [2281], 'Signaling': [2288], 'Technologies': [2289], '(Danvers,': [2290], 'MA).': [2291], 'Conditions': [2292], 'culturing': [2294], 'C2C12': [2295, 2299, 2303, 2423, 2933, 3016, 3201, 3284, 3367, 3409, 3412, 3460, 3487, 3545, 3673, 3708, 3802, 3805, 3855, 3858, 3865, 3918, 4338, 4418, 4423], 'APPL1-suppressed': [2298, 3804, 3857, 3864, 4393], 'scramble': [2301, 3853, 3879], 'control': [2302, 3801, 3854, 3880, 4436], 'HeLa': [2306], 'previous': [2312, 2809], 'studies': [2313, 2794], 'experimental': [2380, 2414, 2790], 'procedure': [2381], 'fractionation': [2384], 'essentially': [2386, 2426, 2802], 'same': [2388, 2428, 2804, 2986], '(39Lim': [2392], 'Wick': [2396], '14006-14011Crossref': [2407], '(74)': [2410], 'procedures': [2415, 2791], 'vitro': [2418, 2480, 4133], 'co-immunoprecipitation': [2421], 'For': [2467, 2599, 3148, 3196], 'detection': [2468], 'between': [2472, 3391, 4005, 4146], 'incubation': [2481], 'performed': [2488, 2756, 2997], 'Kuoppamaa': [2492], 'et': [2493], 'al.': [2494], '(40Kuoppamaa': [2495], 'Skrobuk': [2497], 'Sihvo': [2499], 'Hiukka': [2501], 'Chibalin': [2503], 'A.V.': [2504], 'Zierath': [2505], 'J.R.': [2506, 4040], 'Koistinen': [2507], 'H.A.': [2508], 'Diabetes': [2509], '554-562Crossref': [2515], '(18)': [2518], 'brief,': [2522, 3015], '3-month-old': [2526], 'mice': [2527], 'excised,': [2529], 'cut': [2530], 'small': [2532], 'pieces,': [2533], 'oxygenated': [2535], '30': [2537, 2581, 2662, 3046], 'min': [2538, 3057, 3386], 'Krebs-Henseleit': [2540], 'buffer': [2541, 2573, 2610], '(KHB),': [2542], '5': [2544, 2547, 3170], 'mm': [2545, 2548, 2551, 2612, 2617, 2620, 2624, 2627, 2630, 2634, 2642, 2646, 2649, 3165, 3168, 3171, 3181, 3194], 'HEPES,': [2546, 2613, 3133, 3172], 'glucose,': [2549], '15': [2550], 'mannitol,': [2552], '0.1%': [2554], 'bovine': [2555, 3129], 'serum': [2556, 3543], 'albumin.': [2557], 'samples': [2560, 2585, 2604], 'then': [2562], 'incubated': [2563, 3027, 3216], 'without': [2564, 3492], '(2.5': [2569], 'μg/ml)': [2570, 3141], 'KHB': [2572], '35': [2575], '°C': [2576, 3120], '10,': [2578], '20,': [2579], 'min.': [2582, 2671, 3047], 'immediately': [2587], 'frozen': [2588, 2603], 'liquid': [2590], 'nitrogen': [2591], 'end': [2594], 'treatment': [2597, 2888, 3329, 3357, 3685, 3940], 'period.': [2598], 'extraction,': [2601], 'homogenized': [2606], 'ice-cold': [2608], 'homogenization': [2609], '(50': [2611], 'pH': [2614, 3134, 3173], '7.6,': [2615], '150': [2616], 'NaCl,': [2618, 3166], '20': [2619, 2623, 2670, 3056, 3385, 3508], 'sodium': [2621, 2631], 'pyrophosphate,': [2622], 'β-glycerophosphate,': [2625], '10': [2626, 2651, 2655], 'NaF,': [2628], '2': [2629, 2633, 2641], 'orthophosphate,': [2632], 'EDTA,': [2635], '1%': [2636], 'Nonidet': [2637], 'P-40,': [2638], '10%': [2639], 'glycerol,': [2640], 'phenylmethylsulfonyl': [2643], 'fluoride,': [2644], '1': [2645, 2648, 2688, 3088, 3093, 3193, 3210], 'MgCl2,': [2647], 'CaCl2,': [2650], 'μg/ml': [2652, 2656], 'leupeptin,': [2653], 'aprotinin),': [2657], 'kept': [2658], 'ice': [2660], 'min,': [2663], 'centrifuged': [2665], '14,000': [2667], 'rpm': [2668], 'concentration': [2674], 'supernatant': [2677], 'determined': [2679], 'Bradford': [2682], 'assay.': [2683], 'immunoprecipitated': [2686], 'mg': [2689], 'crude': [2692], 'tissue': [2693], 'specific': [2698, 2712, 2735, 3576], 'APPL1.': [2700], 'Immunoprecipitated': [2701], 'co-immunoprecipitated': [2704], 'detected': [2707, 2725, 3570, 4002], 'Western': [2709, 2727, 3572], 'blotting': [2710], 'these': [2715, 3448, 3715], 'proteins.': [2716], 'levels': [2721, 3568, 4336], 'proteins': [2723], 'blot': [2728, 3573], 'lysates': [2731], 'immunoprecipitation': [2733], 'antibodies.': [2736], 'Quantification': [2737], 'relative': [2740], '(expressed': [2745], 'percentage': [2747, 2847], 'basal': [2749, 3287, 3843], 'phosphorylation,': [2750], 'arbitrarily': [2751], 'set': [2752], '1.0)': [2754], 'using': [2757, 2784, 2902, 2937, 3085, 3150], 'Scion': [2759], 'Image': [2760, 3579], 'Alpha': [2761], '4.0.3.2': [2762], 'program': [2763], '(Scion': [2764], 'Corp.)': [2765], 'normalized': [2767], 'amount': [2770], 'each': [2775], 'experiment.': [2776], 'Statistical': [2777, 2895], 'evaluation': [2778], 'data': [2781, 2899, 4289], 'done': [2783, 2901], 'one-way': [2785, 2903], 'analysis': [2786, 2904, 3232, 3574], 'variance.': [2788, 2906], 'immunofluorescence': [2793], 'study': [2810, 3985], 'calculated': [2852, 2890], 'P': [2854], '=': [2855, 2893, 3241], 'C/(N': [2856], '+': [2857], 'C),': [2858], 'where': [2859, 3245, 3938], 'N': [2860], 'represents': [2861, 2874], 'LKB1.': [2879], 'fold': [2881], 'cytosolically': [2884], 'F': [2892, 3254], 'Ptreated/Pcontrol.': [2894], 'evaluations': [2896], '*,': [2907], 'p': [2908, 2912, 3532], '<': [2909, 2913, 3533], '0.05;': [2910], '**,': [2911], '0.01.': [2914], 'short': [2916], 'hairpin': [2917], 'RNA': [2918, 3151], 'constructs': [2919], 'pSM2': [2922, 2981], '(catalog': [2924], 'number': [2925, 3040], 'RMM1766-96740219,': [2926], 'Open': [2927], 'Biosystems)': [2928], 'stably': [2930, 2979], 'selected': [2936], 'puromycin,': [2938], 'before': [2941, 3212], 'expressing': [2980], 'generated': [2983, 4416], 'method': [2987], 'control.': [2992], 'imaging': [2994, 3111], 'experiments': [2995, 3149, 3197, 3908, 3952], '(41Camacho': [3001], 'Lechleiter': [3003], 'J.D.': [3004], 'Science.': [3005], '260:': [3007], '226-229Crossref': [3008], '(141)': [3011], 'myoblasts': [3017, 3488, 3546, 3709, 3806, 3859], 'seeded': [3019], 'Delta': [3021], 'T': [3022], 'dishes': [3023], '(Bioptechs': [3024], 'Inc.)': [3025], 'Ca2+-sensitive': [3031], 'dye': [3032], '(3': [3033], 'μm,': [3034], 'Fluo-4': [3035, 3218], 'AM,': [3036], 'Molecular': [3037], 'Probes,': [3038], 'catalog': [3039], 'F14202)': [3041], 'room': [3043], 'temperature': [3044], 'After': [3048, 3542], 'careful': [3050], 'washes': [3051], 'phosphate-buffered': [3053], 'saline': [3054], 'fresh': [3059], 'Dulbecco舗s': [3060, 3123], 'modified': [3061, 3124], 'Eagle舗s': [3062, 3125], 'medium,': [3063, 3126], 'imaged.': [3067], 'Images': [3068, 3220, 3227], 'acquired': [3070], 'confocal': [3073], 'laser-scanning': [3074], 'microscope': [3075, 3082], '(Bio-Rad,': [3076], 'MRC-600)': [3077], 'attached': [3078], 'inverted': [3081], '(Nikon': [3083], 'TE200)': [3084], 'ND': [3086], 'filter': [3087], 'rate': [3091], 'frame/s.': [3094], 'We': [3095, 4114, 4328], '20×': [3098], 'water': [3099], '0.45': [3100], 'NA': [3101], 'objective': [3102], '(Plan': [3103], 'Fluor,': [3104], 'Nikon)': [3105], '10-min': [3107], 'recordings.': [3108], 'Loading': [3109], 'carried': [3113], 'out': [3114, 4162], 'recording': [3116], 'media': [3117], '37': [3119], '(12.78': [3121], 'g/liter': [3122], '5%': [3127], 'fetal': [3128], 'serum,': [3130], 'μm': [3132, 3207], '7.2,': [3135], 'no': [3136, 3359, 4003, 4107, 4294], 'phenol': [3137], 'red).': [3138], '(1': [3140], 'initiate': [3145], 'release.': [3147], 'interference': [3152], 'bathed': [3156], 'warm': [3158], 'Rat': [3159], 'Ringer': [3160, 3175, 3188], 'solution': [3161, 3176], 'after': [3162], 'loading': [3163], '(135': [3164], '5.4': [3167], 'KCl,': [3169], '7.2).': [3174], 'prepared': [3178], '1.8': [3180], 'CaCl2': [3182], 'except': [3183], 'zero': [3186], 'solution,': [3189], 'contained': [3192], 'EGTA.': [3195], 'inhibitor': [3199], 'U73122,': [3200], 'preincubated': [3204], '3': [3206], 'h': [3211], 'AM.': [3219], 'analyzed': [3222], 'ImageJ': [3224], '(rsb.info.nih.gov)': [3225], 'software.': [3226], 'filtered': [3230], 'display.': [3234], 'reported': [3238], 'ΔF/F': [3240], '(F': [3242], '−': [3243], 'Frest)/Frest,': [3244], 'Frest': [3246], 'resting': [3249], 'fluorescence,': [3252], 'fluorescence': [3256], 'intensity': [3257], 'any': [3259, 4282], 'time.': [3260], 'To': [3261, 3586, 3783, 3887, 4071, 4412], 'determine': [3262, 3784, 3888], 'activation,': [3274, 3597], 'first': [3276], 'examined': [3277, 3599, 3796, 4085], 'myoblasts.': [3285], 'overexpressed': [3290, 3309, 3675, 3845], '(Fig.': [3291, 3295, 3322, 3343, 3364, 3387, 3427, 3694, 3710, 3860, 3882, 3927, 3948, 3975, 4112, 4134, 4400], '1A)': [3292], 'endogenous': [3294, 3335, 3911], '1C)': [3296], 'mainly': [3300], 'response': [3305, 3446, 4108], 'stimulation,': [3308, 4383], 'cytosol': [3317, 3342, 3693, 4206], 'time-dependent': [3320, 3374, 3418], 'manner': [3321], '1,': [3323, 3344], 'B).': [3326, 3886], 'Similarly,': [3327], 'led': [3330, 3371], 'D).': [3347], 'Overexpressed': [3348], 'effect': [3360, 4140, 4283, 4295], '1E).': [3365], 'Treating': [3366], 'myotubes': [3368], 'AMPKα2,': [3377], 'maximal': [3380], 'observed': [3383], '1F).': [3388], 'correlation': [3390], 'suggests': [3398], 'activated': [3405], 'induced': [3416], 'correlated': [3423], '2).': [3428], 'These': [3429, 4050], 'findings': [3430], 'suggest': [3431, 4052], 'could': [3437, 3956, 4150], 'be': [3438, 4151], 'common': [3440], 'insulin': [3449], 'sensitizers.FIGURE': [3450], '2Metformin-stimulated': [3451], 'A,': [3462], 'time': [3463, 3536], 'course': [3464, 3537], 'metformin-induced': [3466], 'Confocal': [3469], 'microscopy': [3470], 'images': [3471], 'depict': [3472], 'Myc-tagged': [3477, 3915], '(green,': [3479], '2nd': [3480], 'column),': [3481], 'stained': [3482, 3500], 'antibody,': [3485], 'treated': [3489, 3548], '(500': [3494, 3551], 'μm).': [3495], 'nuclei': [3498], 'DAPI': [3502], '(blue,': [3503], '1st': [3504, 3561], 'column).': [3505], 'Scale': [3506], 'bar,': [3507], 'μm.': [3509], 'B,': [3510], 'quantification': [3511], 'error': [3521], 'bars': [3522], 'represent': [3523], 'mean': [3524], '±': [3525], 'S.E.': [3526], 'three': [3528], '***,': [3531], '0.001.': [3534], 'C,': [3535], 'metformin-stimulated': [3539, 3704], 'starvation,': [3544], 'μm)': [3552], 'indicated.': [3554], 'Thr172': [3556], '(P-AMPK,': [3560], 'panel)': [3562, 3567], '(2nd': [3566], 'antibodies.View': [3577], 'Large': [3578], 'Figure': [3580], 'ViewerDownload': [3581], 'Hi-res': [3582], 'image': [3583], 'Download': [3584], '(PPT)': [3585], 'test': [3587, 4072, 4413], 'essential': [3593], 'LKB1SL-26,': [3603], 'nucleus-localized': [3606], 'but': [3607], 'kinase-active': [3608], 'originally': [3611], 'identified': [3612], 'Peutz-Jeghers': [3614], 'syndrome': [3615], 'patients': [3616], 'myoblasts,': [3674, 3919], 'LKB1SL-26': [3676, 3691, 3700], 'exclusively': [3678], 'nucleus,': [3682], 'did': [3686, 4307], '3A).': [3695, 4113], 'addition,': [3697], 'overexpression': [3698], 'inhibited': [3701], 'adiponectin-': [3702], '3,': [3711], 'B–E).': [3712], 'provides': [3724], 'critical': [3740], 'subcellular': [3793, 3896], 'translocation,': [3794, 3897], 'nuclearly': [3849], '4A).': [3861], 'Interestingly,': [3862], 'cytoplasmic': [3869], 'greatly': [3872], 'reduced': [3873, 4341], 'compared': [3874, 4434], '4,': [3883], 'regulates': [3894], 'tested': [3899, 4278], 'if': [3900], 'interact': [3904, 3957], 'Co-immunoprecipitation': [3907], 'showed': [3909, 3986], 'interacts': [3913], 'stimulated': [3924, 4426], '4C).': [3928], 'Similar': [3929], 'association': [3943, 4298], '4D).': [3949], 'Affinity': [3950], 'demonstrated': [3953], 'vitro,': [3961], 'Bin1/amphiphysin/Rvs167': [3965], '(BAR)': [3966], 'involved': [3971], '4E).': [3976], 'agreement': [3978], 'result,': [3981], 'yeast': [3983], 'two-hybrid': [3984], 'BAR': [3990], 'interacted': [3994], '(data': [3997, 4020, 4325], 'shown).': [3999, 4327], 'although': [4009, 4395], 'under': [4010], 'similar': [4012, 4120], 'condition': [4013], 'formed': [4015], 'Akt': [4019], 'shown),': [4022], 'consistent': [4023], 'finding': [4026], 'others': [4028], '(43Mitsuuchi': [4029], 'Johnson': [4031], 'S.W.': [4032], 'Sonoda': [4033], 'Tanno': [4035], 'Golemis': [4037], 'Testa': [4039], 'Oncogene.': [4041], '18:': [4043], '4891-4898Crossref': [4044], '(174)': [4047], 'may': [4058], 'provide': [4059], 'nuclear': [4074, 4101], 'affinity': [4081, 4121, 4183], 'APPL1,': [4083], 'stimulation': [4111, 4167, 4192], 'bound': [4118], '4F),': [4135], 'suggesting': [4136], 'stimulatory': [4139], 'cannot': [4160], 'rule': [4161], 'possibility': [4164], 'causes': [4168], 'post-translational': [4173], 'modification,': [4174], 'allows': [4176, 4200], 'bind': [4179], 'higher': [4182], 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