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4970, 5007, 5176, 5434, 5452, 5485, 5581], 'DNA': [11, 191, 374, 705, 1144, 2404, 3622, 4252, 4260, 4268, 4995, 5053, 5134], 'repair/transcription': [12, 192], 'factor,': [13, 193], 'yeast': [15, 195, 552, 1152, 1341, 2001, 2009, 2461, 2590, 2633, 2932, 2964, 3497, 3714, 4490, 5554, 5597, 5706], 'four-hybrid': [16, 196, 1153, 2002, 2933, 2965, 4491, 4668], 'system': [17, 197, 554, 2003, 4492, 4669, 4828], 'was': [18, 34, 52, 198, 214, 232, 1386, 1484, 1518, 1575, 1613, 1635, 1736, 1743, 1950, 2495, 2504, 2839, 3005, 4274, 4332, 4641, 4845], 'designed.': [19, 199], 'When': [20, 200, 4117], 'ternary': [22, 202, 1158, 2085, 2601, 2889, 4495, 4512, 4546, 4635], 'Cdk-activating': [23, 203, 368, 4652], 'kinase': [24, 204, 369, 896, 2511, 4653, 5197, 5468], '(CAK)': [25, 205], 'complex': [26, 74, 206, 254, 607, 638, 686, 836, 897, 1160, 1998, 2086, 2546, 2574, 2603, 2890, 3093, 3745, 4061, 4195, 4496, 4513, 4525, 4547, 4592, 4597, 4637, 5021, 5454, 5483, 5492], 'composed': [27, 207, 640], 'Cdk7,': [29, 209, 909, 1803, 2088, 2605, 3717, 3958, 4184], 'cyclin': [30, 210, 916, 1804, 2089, 2480, 2532, 2606, 3152, 3718, 3959, 4031, 4412, 4419, 5535], 'H,': [31, 211, 1444, 1805, 2090, 2533, 2607, 3719, 3960], 'and': [32, 65, 212, 245, 377, 537, 617, 628, 649, 695, 711, 813, 827, 837, 882, 918, 1013, 1082, 1146, 1200, 1334, 1348, 1409, 1433, 1445, 1497, 1507, 1509, 1524, 1537, 1545, 1557, 1564, 1624, 1652, 1717, 1759, 1786, 1807, 1814, 1916, 1933, 1956, 2091, 2262, 2393, 2465, 2482, 2575, 2597, 2608, 2798, 2882, 2943, 2975, 3099, 3119, 3156, 3265, 3273, 3319, 3344, 3469, 3483, 3683, 3720, 3766, 3812, 3942, 3961, 3994, 4015, 4023, 4030, 4083, 4106, 4139, 4154, 4169, 4205, 4251, 4317, 4374, 4443, 4560, 4655, 4719, 4799, 4997, 5059, 5181, 5430, 5534, 5543, 5575, 5588, 5700, 5707, 5758, 5767, 5772, 5778, 5786, 5794], 'MAT1': [33, 70, 213, 250, 919, 1287, 1612, 1633, 2092, 2503, 3106, 3190, 3878, 3892, 3897, 4000, 4012, 4149, 4223, 4403, 4431, 4978, 5078, 5182, 5366, 5398, 5512, 5547], 'used': [35, 215, 608, 1166, 1387, 1532, 1566, 1951, 2893, 4577, 5732], 'as': [36, 54, 216, 234, 399, 401, 405, 414, 550, 560, 609, 1018, 1168, 1204, 1206, 1311, 1344, 1352, 1415, 1819, 1968, 2006, 2064, 2149, 2154, 2327, 2329, 2536, 2610, 2745, 2802, 2808, 2810, 2894, 3037, 3732, 3734, 4108, 4497, 4526, 4681, 4855, 4857, 5204, 5580], 'bait,': [37, 217, 2611, 4527], 'xeroderma': [39, 219, 366], 'pigmentosum': [40, 220, 367, 823], '(XP)': [41, 221], 'D': [42, 222], 'helicase': [43, 116, 223, 296, 1199, 1303, 1954, 2992, 3256, 3340, 3419, 4327, 4365, 4389, 4463, 4722, 5008, 5035, 5084, 5106, 5462], 'transcription': [45, 225, 360, 363, 511, 684, 708, 1262, 2438, 3620, 4250, 5058], 'factor': [46, 226, 361, 364, 449, 634, 2781, 2913], 'IIH': [47, 227, 365], '(TFIIH),': [48, 228], 'among': [49, 229, 4674], 'other': [50, 230, 529, 1258, 1958, 2263, 2474, 2765, 3471, 3986, 4163, 5496], 'proteins,': [51, 231], 'identified': [53, 233, 652, 1257, 2669, 2793, 2902, 2929, 2961, 4671], 'an': [55, 235, 2155, 2746, 4271], 'interacting': [56, 236, 577, 2747, 2899, 4842], 'partner.': [57, 237], 'Deletion': [58, 238], 'mutant': [59, 239, 4071], 'analyses': [60, 240], 'demonstrated': [61, 241, 1276, 3729, 3869, 4846], 'that': [62, 108, 138, 242, 288, 318, 515, 523, 542, 581, 871, 1086, 1156, 1191, 1277, 1299, 1794, 2079, 2523, 2645, 3077, 3127, 3326, 3534, 3730, 3756, 3767, 3786, 3799, 3874, 4008, 4021, 4046, 4085, 4193, 4210, 4273, 4450, 4676, 4847, 4966, 5093, 5151, 5356, 5729], 'coiled-coil': [64, 244, 1284, 3939, 3992, 5509], 'hydrophobic': [67, 247, 3945, 3996, 5550], 'domains': [68, 248], 'interlink': [71, 251], 'CAK': [73, 99, 113, 159, 168, 253, 279, 293, 339, 348, 1080, 1141, 1159, 1167, 1280, 1300, 2080, 2164, 2602, 3131, 3492, 3744, 3765, 4060, 4105, 4118, 4166, 4211, 4308, 4382, 4457, 4524, 4654, 4854, 5200, 5516], 'directly': [75, 255, 4334], 'with': [76, 87, 111, 149, 153, 256, 267, 291, 329, 333, 546, 1261, 1505, 1923, 1937, 2166, 2435, 2592, 2657, 2749, 2825, 2879, 2938, 2970, 2994, 3031, 3193, 3413, 3461, 3490, 3552, 3716, 3725, 3955, 4007, 4028, 4094, 4100, 4121, 4180, 4227, 4320, 4402, 4422, 4666, 4930, 5015, 5112, 5594, 5669], 'N-terminal': [78, 258, 3083, 3335, 3459, 3504, 3758, 3933, 5502, 5526], 'domain': [79, 259, 1285, 2406, 2429, 3004, 3759, 3993, 5510], 'XPD.': [81, 119, 261, 299], 'Using': [82, 262, 2599], 'immunoprecipitates': [83, 263], 'from': [84, 264, 961, 1584, 1665, 1731, 2488, 2496, 2619, 3181, 3291, 5040, 5739], 'cells': [85, 265, 1275, 3027, 4093, 5424], 'coinfected': [86, 266, 4091, 4313], 'baculoviruses,': [88, 268], 'we': [89, 106, 269, 286, 579, 1149, 1165, 1256, 1531, 2612, 2668, 2761, 2791, 2987, 3276, 3447, 3887, 4090, 4311, 4486, 4961, 5341], 'further': [90, 270, 563, 1269, 1298, 2983, 4077, 4829, 5734], 'validated': [91, 271, 1185], 'bridging': [93, 273, 4588], 'function': [94, 161, 274, 341], 'XPD,': [96, 276, 648, 1802, 3507, 3962, 4122, 4220, 4310, 4456, 5004, 5141], 'which': [97, 277, 392, 646, 833, 913, 1021, 1174, 1266, 2143, 2409, 2432, 2527, 2552, 2838, 2887, 3000, 3278, 3337, 3349, 3500, 3802, 3889, 4221, 4521, 4595, 4629, 5005, 5045, 5118, 5129, 5494, 5571], 'anchors': [98, 278], 'to': [100, 126, 280, 306, 573, 625, 816, 869, 878, 883, 963, 1288, 1326, 1643, 1746, 1942, 2057, 2402, 2426, 2519, 2624, 2816, 2823, 2896, 3008, 3014, 3269, 3530, 3632, 3774, 3784, 3976, 4003, 4036, 4150, 4213, 4276, 4383, 4455, 4499, 4553, 4578, 4584, 4646, 4797, 4810, 4838, 4863, 4976, 5023, 5028, 5048, 5056, 5064, 5091, 5122, 5162, 5165, 5173, 5351, 5368, 5402, 5419, 5425, 5433, 5448, 5561, 5592, 5702, 5753, 5783], 'core': [102, 132, 282, 312, 1290, 4215, 4974, 5114, 5566], 'TFIIH.': [103, 133, 283, 313, 901, 5115, 5480], 'In': [104, 284, 589, 1254, 2789, 3066, 4177, 4480, 4551, 5337, 5395], 'addition': [105, 285, 4380, 4552, 4862], 'show': [107, 287, 1297, 3325], 'upon': [109, 124, 289, 304, 1178, 4400, 5013], 'interaction': [110, 290, 620, 2449, 3412, 3819, 3895, 4142, 4401, 5014, 5178], 'MAT1,': [112, 154, 292, 334, 1806, 2483, 5016, 5128, 5557], 'inhibits': [114, 294, 1301], 'activity': [117, 297, 390, 1304, 2946, 2978, 3159, 3420, 4005, 4272, 4328, 4390, 4464, 5036, 5042, 5107, 5191, 5198, 5463], 'This': [120, 300, 611, 866, 1323, 4044, 4141, 4207, 4470, 4627, 4791, 5416], 'inhibition': [121, 301, 1318, 4398, 4429], 'is': [122, 135, 302, 315, 393, 636, 1321, 2081, 2400, 2424, 2553, 3085, 3112, 3132, 3154, 3165, 3257, 3762, 3803, 3879, 4119, 4155, 4217, 4254, 4366, 4432, 4438, 4446, 4453, 4542, 4568, 4984, 4993, 5010, 5148, 5417, 5455, 5484, 5522], 'overcome': [123, 303], 'binding': [125, 305, 2405, 3738, 4147, 4159, 5063, 5138, 5161], 'p44,': [127, 150, 307, 330, 3414, 4107, 4185, 4969, 5163], 'subunit': [129, 309, 2674, 4174, 4201, 4971, 4979, 5067, 5513], 'It': [134, 314, 2517, 3780, 4017, 4445, 4844, 5147], 'not': [136, 147, 316, 327, 3108, 3804, 3974, 4459, 4543, 5054, 5071, 5096, 5158, 5187, 5431, 5442, 5456, 5742], 'surprising': [137, 317], 'under': [139, 319, 2505, 2555], 'these': [140, 320, 516, 569, 802, 874, 2451, 3124, 3753, 3778, 3950, 4242, 4330, 4505], 'conditions': [141, 321], 'some': [142, 322, 806, 1014, 1331, 2764, 3568, 3768, 4047, 5123, 5152, 5346, 5740], 'XPD': [143, 323, 696, 1198, 1278, 1306, 1332, 1483, 1541, 2671, 2991, 3020, 3082, 3196, 3255, 3266, 3281, 3288, 3327, 3356, 3418, 3450, 3477, 3541, 3562, 3572, 3629, 3741, 3761, 3769, 4054, 4097, 4129, 4151, 4187, 4248, 4364, 4384, 4388, 4462, 4475, 4721, 4967, 5031, 5038, 5066, 5083, 5155, 5180, 5190, 5505, 5586], 'mutations': [144, 324, 800, 3267, 3353, 3569, 3630, 5153], 'affect': [145, 325, 805, 3610, 5157], 'interactions': [146, 326, 398, 539, 567], 'only': [148, 328, 2818, 4804, 5072, 5108, 5159, 5457, 5573], 'but': [151, 331, 5079, 5171, 5194, 5464, 5741], 'also': [152, 332, 914, 2534, 2762, 4056, 4447, 4528, 4569, 5080, 5172, 5465, 5473], 'thus': [155, 335, 1083, 2567, 5017, 5149], 'preventing': [156, 336, 2568], 'either': [157, 337, 680, 2148, 3007, 3103, 4125, 4262, 4404, 4587, 5132], 'inhibitory': [160, 340], 'within': [162, 169, 342, 349, 568, 2478, 3571, 4473, 5192], 'CAK·XPD': [163, 343, 3092, 3818, 4088, 4858, 4991, 5020, 5097], 'and/or': [164, 344, 572, 3621, 5135, 5208], 'TFIIH': [170, 350, 450, 635, 699, 812, 1203, 1291, 1328, 2152, 2169, 3619, 4082, 4216, 4864, 4975, 5193, 5491, 5670, 5709, 5747], 'and,': [171, 351, 3616, 3971], 'consequently,': [172, 352], 'explaining': [173, 353], 'variety': [175, 355], 'XP': [178, 358, 5169], 'phenotypes.': [179, 359], 'IID': [362], 'β-galactosidase': [370, 2469], 'FUSE-binding': [371, 2843], 'protein-interacting': [372, 1211], 'repressor': [373], 'replication,': [375], 'transcription,': [376, 1143], 'translation': [378], 'are': [379, 508, 543, 834, 1087, 2935, 2967, 3107, 3358, 3973, 4033, 4055, 5360, 5498, 5537, 5544, 5751, 5781], 'regulated': [380, 527], 'through': [381, 1602, 4145, 4516], 'ordered': [383], 'formation': [384, 2570, 3089, 3183, 3510, 3612, 3883, 3979, 4598, 4820, 5411], 'large': [386, 411, 570], 'protein': [387, 402, 595, 624, 1214, 1815, 1898, 1927, 2398, 2777, 2909, 4315, 4509, 4636, 4687, 4817, 4851, 5792], 'complexes,': [388], 'often': [394], 'modulated': [395], 'by': [396, 528, 602, 681, 688, 1189, 1313, 1486, 1520, 1549, 1577, 1615, 1656, 1964, 2637, 2842, 3764, 4067, 4157, 4219, 4279, 4368, 4411, 4418, 4430, 5127, 5145, 5546], 'protein-protein': [397], 'well': [400, 1205, 2328, 2809, 3560, 3733, 4856], 'modifications': [403], 'such': [404, 413, 549, 590, 1017, 1343, 2063, 5203], 'phosphorylation,': [406], 'acetylation,': [407], 'methylation,': [408], 'etc.': [409], 'Several': [410, 902], 'complexes': [412, 488, 517, 571, 3188, 4331, 4859, 4992], 'RNA': [415, 954, 2835, 5205], 'polymerases': [416], '(1Ebright': [417], 'R.H.': [418], 'J.': [419, 749, 842, 927, 941, 978, 997, 1051, 1062, 1224, 1234, 1397, 1459, 1462, 1593, 1683, 1879, 2023, 2026, 2112, 2134, 2177, 2198, 2227, 2276, 2278, 2312, 2708, 2729, 2846, 2856, 3206, 3209, 3237, 3308, 3849, 3852, 3916, 4608, 4611, 4689, 4699, 4730, 4773, 4872, 4894, 4945, 5259, 5270, 5321, 5386, 5616, 5646, 5756, 5787], 'Mol.': [420, 497, 663, 723, 1096, 1239, 1830, 2382, 2686, 2861, 4704, 5219, 5300], 'Biol.': [421, 499, 998, 1063, 1463, 1684, 1880, 2027, 2199, 2384, 2730, 3210, 3238, 3853, 3917, 4612, 4946, 5271, 5322, 5617, 5647], '2000;': [422, 1065, 1113, 1241, 1686, 1882, 2201, 2343, 2732, 2863, 3240, 3855, 3919, 4706, 4948, 5273, 5302, 5324, 5649, 5687], '304:': [423], '687-698Crossref': [424], 'PubMed': [425, 441, 464, 503, 673, 733, 753, 775, 794, 861, 931, 945, 986, 1008, 1045, 1073, 1102, 1116, 1249, 1401, 1473, 1597, 1694, 1840, 1862, 1890, 1988, 2037, 2052, 2116, 2138, 2181, 2209, 2231, 2257, 2282, 2299, 2322, 2346, 2388, 2696, 2712, 2740, 2871, 3220, 3248, 3312, 3367, 3402, 3441, 3604, 3658, 3698, 3837, 3863, 3927, 4298, 4355, 4622, 4714, 4734, 4760, 4786, 4876, 4898, 4924, 4956, 5229, 5253, 5281, 5310, 5332, 5390, 5627, 5657, 5695], 'Scopus': [426, 442, 465, 481, 504, 674, 734, 754, 776, 795, 850, 862, 932, 946, 987, 1009, 1046, 1074, 1103, 1117, 1250, 1402, 1474, 1598, 1695, 1841, 1863, 1891, 1989, 2038, 2053, 2117, 2139, 2182, 2210, 2232, 2258, 2283, 2300, 2323, 2347, 2389, 2697, 2713, 2741, 2872, 3221, 3249, 3313, 3368, 3403, 3442, 3605, 3659, 3699, 3838, 3864, 3928, 4299, 4356, 4623, 4715, 4735, 4761, 4787, 4877, 4899, 4925, 4957, 5230, 5254, 5282, 5311, 5333, 5391, 5628, 5658, 5696], '(194)': [427], 'Google': [428, 444, 467, 483, 506, 676, 736, 756, 778, 797, 852, 864, 934, 948, 989, 1011, 1048, 1076, 1105, 1119, 1252, 1404, 1476, 1600, 1697, 1843, 1865, 1893, 1991, 2040, 2055, 2119, 2141, 2184, 2212, 2234, 2260, 2285, 2302, 2325, 2349, 2391, 2699, 2715, 2743, 2874, 3223, 3251, 3315, 3370, 3405, 3444, 3607, 3661, 3681, 3701, 3840, 3866, 3930, 4301, 4358, 4625, 4717, 4737, 4763, 4789, 4879, 4901, 4927, 4959, 5232, 5256, 5284, 5313, 5335, 5393, 5630, 5660, 5698], 'Scholar),': [429, 445, 484, 1012, 2056, 2142, 2286, 2303, 2744, 3662, 3682, 3931], 'TFIID1': [430], '(2Bell': [431], 'B.': [432, 1419, 1676, 1872, 2191, 2722, 3230, 3304, 3320, 3375, 3577, 3909, 4938, 5759], 'Tora': [433], 'L.': [434, 1226, 2373, 2848, 4691, 5639, 5788], 'Exp.': [435], 'Cell': [436], 'Res.': [437, 3654, 3677], '1999;': [438, 665, 725, 791, 1099, 1594, 1832, 2688, 3309, 5221], '246:': [439], '11-19Crossref': [440], '(109)': [443], 'transcription/DNA': [447, 632], 'repair': [448, 633, 3623, 4253, 4996, 5060], '(3Hoeijmakers': [451], 'J.H.J.': [452], 'Egly': [453, 473, 661, 721, 744, 768, 924, 1032, 1056, 1109, 1123, 1235, 1422, 1460, 1681, 1828, 1855, 1877, 1981, 2024, 2174, 2196, 2224, 2339, 2353, 2684, 2705, 2727, 2857, 3207, 3235, 3434, 3830, 3850, 3914, 4291, 4348, 4609, 4700, 4727, 4869, 4891, 4943, 5217, 5240, 5264, 5296, 5684], 'J.M.': [454, 474, 662, 722, 769, 925, 1033, 1057, 1110, 1124, 1423, 1461, 1682, 1829, 1856, 1878, 1982, 2025, 2175, 2197, 2225, 2340, 2354, 2685, 2706, 2728, 3208, 3236, 3435, 3831, 3851, 3915, 4292, 4349, 4610, 4728, 4870, 4892, 4944, 5218, 5241, 5265, 5297, 5685], 'Vermeulen': [455], 'W.': [456, 1939, 5635, 5754], 'Curr.': [457, 2046], 'Opin.': [458, 2047], 'Genet.': [459, 771, 1858, 1984, 3437, 3833, 4294, 4351], 'Dev.': [460, 857, 3363], '1996;': [461, 478, 1000, 1398, 2228, 2254, 4757, 4783, 4895, 4921], '6:': [462, 5303], '26-33Crossref': [463], '(156)': [466], 'Scholar,': [468, 737, 757, 779, 853, 935, 990, 1049, 1106, 1120, 1844, 1866, 2041, 2120, 2185, 2213, 2235, 2350, 2365, 2700, 2716, 3224, 3371, 3841, 4738, 4880, 4902, 5233, 5257, 5285, 5314, 5631], '4Svejstrup': [469], 'J.Q.': [470, 5609], 'Vichi': [471], 'P.': [472, 1035, 1059, 1094, 1126, 1359, 1589, 2356, 5243, 5267, 5675], 'Trends': [475], 'Biochem.': [476], 'Sci.': [477, 787, 1098, 2250, 3395, 3597, 4753, 4779, 4917], '20:': [479, 773, 1860, 1986, 3439, 3835, 4296, 4353, 5388], '346-350Crossref': [480], '(213)': [482], 'or': [485, 555, 687, 2011, 2068, 2153, 2334, 2443, 2447, 2785, 3013, 3055, 3105, 3195, 4128, 4171, 4186, 4266, 4416, 4583, 4593, 5095], 'mediator': [487], '(5Lee': [489], 'Y.C.': [490], 'Min': [491], 'S.': [492, 765, 789, 1029, 1053, 1852, 1978, 2128, 2244, 2252, 3387, 3397, 3431, 3589, 3599, 3642, 3646, 3827, 4288, 4345, 4747, 4755, 4781, 4911, 4919, 5237, 5261, 5299, 5677, 5770, 5795], 'Gim': [493], 'B.S.': [494], 'Kim': [495], 'Y.J.': [496], 'Cell.': [498, 664, 724, 979, 1036, 1095, 1240, 1831, 2292, 2315, 2383, 2687, 2862, 4705, 5220, 5244, 5301, 5686], '1997;': [500, 750, 928, 942, 1037, 1465, 2029, 2049, 2178, 2385, 2709, 3212, 3399, 3601, 4614, 4731, 4873, 5245, 5619], '17:': [501, 2386], '4622-4632Crossref': [502], '(64)': [505], 'Scholar)': [507, 1601, 2261, 3316, 3608, 4718, 4960, 5699], 'involved': [509, 1088, 1215, 2767, 3805], 'in': [510, 801, 1089, 1142, 1216, 1273, 1361, 1427, 1511, 1637, 1781, 1798, 1811, 1902, 1999, 2007, 2145, 2415, 2513, 2562, 2648, 2758, 2768, 2828, 2886, 2903, 2930, 2952, 2962, 2999, 3052, 3142, 3176, 3263, 3348, 3355, 3494, 3635, 3713, 3777, 3791, 3806, 4049, 4098, 4249, 4642, 4848, 4861, 4994, 5043, 5100, 5154, 5345, 5362, 5460, 5466, 5530, 5596, 5705], 'initiation.': [512], 'ensure': [514], 'work': [518, 4932], 'properly,': [519], 'it': [520, 3528, 4574, 4983, 5103, 5110, 5446], 'seems': [521, 5701], 'likely': [522, 615, 957, 5150], 'they': [524], 'might': [525, 5156, 5342], 'be': [526, 585, 626, 1162, 1176, 1268, 2485, 2520, 2560, 2892, 3329, 3531, 3772, 3899, 4019, 4237, 4277, 4549, 4576, 4631, 5120, 5143, 5369, 5403, 5449, 5562, 5703, 5731], 'cellular': [530], 'components.': [531], 'These': [532, 2876, 3708], 'regulations': [533], 'may': [534, 5130, 5725], 'involve': [535], 'subtle': [536], 'weak': [538, 3172], 'between': [540, 621, 2450, 5179, 5715], 'partners': [541, 2475, 4665], 'hardly': [544], 'detectable': [545], 'classical': [547], 'methods': [548, 1342], 'two-hybrid': [553, 5598], 'immunoprecipitation': [556], 'using': [557, 1490, 1521, 1554, 1619, 4069, 4493], 'one': [558, 2397, 2750, 3258, 3456, 4225, 4536], 'partner': [559, 2399, 2423, 2748, 4539, 5583], 'bait.': [561, 610, 630], 'internal': [566, 4532], 'identify': [574, 4839], 'externally': [576], 'partner(s),': [578], 'theorize': [580], 'bait': [583, 1169, 2895, 4498], 'should': [584, 2004, 2484, 4018], 'multiprotein': [587, 4801, 5748], 'complex.': [588, 3983, 4191, 5749], 'case,': [592], 'target': [594, 623, 4508, 4658, 4816], 'would': [596, 1175, 3609], 'recognize': [597], 'specific': [599, 2412, 4795], 'structure': [600, 3289, 3293, 5478], 'displayed': [601], 'subunits': [604, 2167, 2797, 3493, 4103, 4133, 4164, 5497, 5540, 5717, 5744], 'multipoint': [612, 4517], 'surface': [613], 'will': [614, 1267, 2433, 5186], 'increase': [616], 'stabilize': [618], 'characterized': [627], 'The': [631, 1127, 1377, 1540, 1608, 1646, 1738, 1993, 2357, 2440, 2956, 4244, 4326, 5026, 5116, 5470, 5501], 'enzyme': [639], 'nine': [642], 'subunits,': [643], 'three': [644, 817, 3339, 3636, 3902, 3951], '(XPB,': [647], 'Cdk7)': [650], 'have': [651, 889, 904, 2585, 2662, 2792, 4487, 4677, 4962, 5441, 5718], 'enzymatic': [653, 809, 875], 'activities': [654, 810, 876, 2661], '(6Tirode': [655, 715, 1822, 2678, 5211], 'F.': [656, 660, 716, 720, 759, 1357, 1421, 1451, 1455, 1823, 1827, 1846, 1972, 2015, 2019, 2679, 2683, 3198, 3202, 3425, 3821, 4282, 4339, 4600, 4604, 5212, 5216, 5768], 'Busso': [657, 717, 1824, 2680, 5213], 'D.': [658, 718, 976, 1232, 1238, 1672, 1825, 1868, 2098, 2187, 2246, 2681, 2718, 2854, 2860, 3226, 3905, 4697, 4703, 4749, 4913, 4934, 5214, 5287, 5683], 'Coin': [659, 719, 1826, 2682, 5215], '3:': [666, 726, 1833, 2689, 5222], '87-95Abstract': [667, 727, 1834, 2690, 5223], 'Full': [668, 670, 728, 730, 847, 983, 1003, 1005, 1040, 1042, 1068, 1070, 1244, 1246, 1468, 1470, 1689, 1691, 1835, 1837, 1885, 1887, 2032, 2034, 2204, 2206, 2296, 2319, 2691, 2693, 2735, 2737, 2866, 2868, 3215, 3217, 3243, 3245, 3858, 3860, 3922, 3924, 4617, 4619, 4709, 4711, 4951, 4953, 5224, 5226, 5248, 5250, 5276, 5278, 5305, 5307, 5327, 5329, 5622, 5624, 5652, 5654, 5690, 5692], 'Text': [669, 671, 729, 731, 848, 984, 1004, 1006, 1041, 1043, 1069, 1071, 1245, 1247, 1469, 1471, 1690, 1692, 1836, 1838, 1886, 1888, 2033, 2035, 2205, 2207, 2297, 2320, 2692, 2694, 2736, 2738, 2867, 2869, 3216, 3218, 3244, 3246, 3859, 3861, 3923, 3925, 4618, 4620, 4710, 4712, 4952, 4954, 5225, 5227, 5249, 5251, 5277, 5279, 5306, 5308, 5328, 5330, 5623, 5625, 5653, 5655, 5691, 5693], 'PDF': [672, 732, 849, 985, 1007, 1044, 1072, 1248, 1472, 1693, 1839, 1889, 2036, 2208, 2298, 2321, 2695, 2739, 2870, 3219, 3247, 3862, 3926, 4621, 4713, 4955, 5228, 5252, 5280, 5309, 5331, 5626, 5656, 5694], '(257)': [675, 735, 1842, 2698, 5231], 'Scholar).': [677, 798, 865, 949, 1077, 1135, 1253, 1376, 1405, 1442, 1477, 1698, 1894, 1992, 2875, 3252, 3406, 3445, 3867, 4302, 4359, 4626, 4790, 4928, 5336, 5394, 5661], 'Once': [678], 'recruited': [679], 'stable': [683, 2084], 'preinitiation': [685], 'damage': [690], 'recognition': [691], 'complex,': [692, 3514, 5517], 'XPB': [694], 'helicases': [697], 'induce': [700], 'opening': [702], 'around': [706, 4261, 5493], 'start': [709, 4264], 'site': [710, 1640, 4265, 5139], 'lesion,': [713], 'respectively': [714], '7Evans': [738], 'E.': [739, 968, 3373, 3377, 3575, 3579, 3847, 4769, 5291, 5380], 'Moggs': [740], 'J.G.': [741], 'Hwang': [742], 'J.R.': [743], 'J.-M.': [745, 1236, 2858, 3813, 4701], 'Wood': [746], 'R.D.': [747, 5615, 5643], 'EMBO': [748, 926, 940, 1396, 1592, 2111, 2133, 2176, 2226, 2277, 2707, 3307, 4729, 4871, 4893, 5385], '16:': [751, 929, 943, 2179, 2710, 4732, 4874], '6559-6573Crossref': [752], '(402)': [755], '8Coin': [758, 1845], 'Marinoni': [760, 1847, 1973, 3426, 3645, 3822, 4283, 4340], 'J.C.': [761, 1848, 1974, 2100, 2108, 3427, 3823, 4284, 4341], 'Rodolfo': [762, 1849, 1975, 3428, 3824, 4285, 4342], 'C.': [763, 974, 1027, 1061, 1453, 1587, 1850, 1976, 2017, 2379, 3200, 3306, 3389, 3429, 3591, 3825, 3845, 4286, 4343, 4602, 5235, 5269, 5320], 'Fribourg': [764, 1851, 1977, 3430, 3826, 4287, 4344, 5676], 'Pedrini': [766, 1853, 1979, 3432, 3828, 4289, 4346], 'A.M.': [767, 1854, 1980, 2096, 2126, 3433, 3829, 4290, 4347], 'Nat.': [770, 1857, 1983, 3436, 3832, 4293, 4350], '1998;': [772, 1859, 1985, 3438, 3834, 4295, 4352], '184-188Crossref': [774, 1861, 1987, 3440, 3836, 4297, 4354], '(312)': [777, 1864, 1990, 3443, 3839, 4300, 4357], '9Holstege': [780], 'F.C.': [781, 1389], 'Young': [782], 'R.A.': [783], 'Proc.': [784, 2247, 3392, 3594, 4750, 4776, 4914], 'Natl.': [785, 2248, 3393, 3595, 4751, 4777, 4915], 'Acad.': [786, 2249, 3394, 3596, 4752, 4778, 4916], 'U.': [788, 2251, 3396, 3598, 4754, 4780, 4918], 'A.': [790, 966, 970, 992, 1122, 1674, 1678, 1870, 1874, 2094, 2189, 2193, 2253, 2352, 2720, 2724, 3045, 3228, 3232, 3381, 3391, 3398, 3583, 3593, 3600, 3669, 3907, 3911, 4116, 4756, 4771, 4782, 4920, 4936, 4940, 5374, 5378, 5679], '96:': [792], '2-4Crossref': [793], '(32)': [796], 'Interestingly,': [799, 4396], 'two': [803, 2452, 2473, 2490, 2794, 2811, 3332, 3449, 4162, 4672], 'proteins': [804, 1016, 1085, 1259, 2454, 2766, 3485, 4581, 4589, 4673], 'give': [814], 'rise': [815], 'autosomal': [818], 'recessive': [819], 'genetic': [820], 'disorders,': [821], 'Xeroderma': [822], '(XP),': [824], 'Cockayne': [825, 3271], 'syndrome,': [826, 3272], 'trichothiodystrophy,': [828], 'corresponding': [830, 1513, 1660], 'phenotypes': [831, 881, 3770], 'rather': [835, 5195, 5568], 'diverse': [838, 2805], '(10Hoeijmakers': [839], 'J.H.': [840], 'Eur.': [841], 'Cancer.': [843], '1994;': [844, 2293, 2316], '13:': [845], '1912-1921Abstract': [846], '(112)': [851], '11Lehmann': [854], 'A.R.': [855, 3361], 'Genes': [856, 3362], '2001;': [858, 3364, 5387], '15:': [859, 1399, 2229, 3365, 4896], '15-23Crossref': [860, 3366], '(307)': [863, 3369], 'prompted': [867], 'us': [868, 1325, 5090], 'hypothesize': [870, 5092], 'disruption': [872], 'contributes': [877], 'observed': [880, 3175], 'elucidate': [884], 'molecular': [886], 'mechanisms.': [887], 'We': [888, 1183, 1296, 2073, 2584, 3046, 3564, 4232, 5750, 5780], 'focused': [890], 'our': [891, 2666, 2884, 2985, 3177, 4377, 4827, 5087], 'attention': [892], 'on': [893, 1709, 1714, 1720, 1753, 1788, 2462, 2639, 3060, 3063, 4224, 4229, 4309, 4335, 5476, 5736], 'Cdkactivating': [895], '(CAK),': [898], 'part': [899, 910, 1201, 2150, 3279, 3464, 3539, 4052, 5503, 5527, 5563], 'studies': [903], 'detailed': [905], 'CAK,': [912, 2479, 4684], 'contains': [915, 4196, 5572], 'H': [917, 2481, 2494, 2596, 3153, 4032, 4413, 4420, 5536], '(12Rossignol': [920, 2170, 4723, 4865], 'M.': [921, 1031, 2110, 2124, 2171, 2217, 2308, 2702, 3301, 3379, 3581, 3640, 3671, 3686, 4724, 4866, 4884, 5239, 5382], 'Kolb-Cheynel': [922, 2172, 2703, 4725, 4867, 5785], 'I.': [923, 1228, 2173, 2704, 2850, 4693, 4726, 4868, 5784], '1628-1637Crossref': [930, 2180, 2711, 4733, 4875], '(168)': [933, 2183, 2714, 4736, 4878], '13Yankulov': [936], 'K.': [937, 2270, 2310, 2375, 3297, 3665, 3688, 5773], 'Bentley': [938], 'D.L.': [939], '1638-1646Crossref': [944], '(153)': [947], 'Indeed,': [950, 2548, 5175], 'Cdk7': [951, 2477, 3104, 3194, 4127, 4423, 5533], 'phosphorylates': [952, 1081], 'both': [953, 4557], 'polymerase': [955, 1487, 1550, 1616, 2836, 5206], 'II,': [956, 2778, 2837], 'favoring': [958], 'transition': [960], 'initiation': [962], 'elongation': [964, 2780, 2912], '(14Usheva': [965], 'Maldonado': [967], 'Goldring': [969], 'Lu': [971], 'H.': [972, 1230, 2242, 2502, 2852, 3385, 3587, 4695, 4745, 4767, 4909, 5577], 'Houbavi': [973], 'Reinberg': [975, 2245, 4748, 4912], 'Aloni': [977], '1992;': [980, 3655], '69:': [981], '871-881Abstract': [982], '(179)': [988], '15Dvir': [991], 'Conaway': [993, 995], 'R.C.': [994, 5295], 'J.W.': [996], 'Chem.': [999, 1064, 1464, 1685, 1881, 2028, 2200, 2731, 3211, 3239, 3854, 3918, 4613, 4947, 5272, 5323, 5618, 5648], '271:': [1001], '23352-23356Abstract': [1002], '(52)': [1010], 'DNA-binding': [1015], 'nuclear': [1019, 2332, 5209], 'receptors,': [1020], 'activate': [1022], 'their': [1023], 'responsive': [1024], 'genes': [1025, 2062, 5440], '(16Rochette-Egly': [1026], 'Adam': [1028, 5236], 'Rossignol': [1030, 2216, 4883, 5238], 'Chambon': [1034, 1058, 1588, 5242, 5266], '90:': [1038, 5246], '97-107Abstract': [1039, 5247], '(259)': [1047, 5255], '17Bastien': [1050, 5258], 'Adam-Stitah': [1052, 5260], 'Riedl': [1054, 5262, 5288], 'T.': [1055, 1108, 2274, 2338, 3644, 3690, 3843, 5263, 5289], 'Rochette-Egly': [1060, 5268], '275:': [1066, 1687, 1883, 2202, 2733, 3241, 3856, 3920, 4949, 5274, 5325, 5650], '21896-21904Abstract': [1067, 5275], '(91)': [1075, 5283], 'Furthermore,': [1078], 'free': [1079, 5099], 'regulates': [1084, 2528], 'cell': [1091, 1147, 1733, 2147, 2159, 2621, 4850], 'cycle': [1092, 2160], '(18Kaldis': [1093], 'Life': [1097], '55:': [1100, 3679], '284-296Crossref': [1101], '(185)': [1104], '19Riedl': [1107, 2337], 'Gene': [1111, 2341], 'Expr.': [1112, 2342], '9:': [1114, 2344], '3-13Crossref': [1115, 2345], '(47)': [1118, 2054, 2348], '20Keriel': [1121, 2351], 'Kaldis': [1125, 2355], 'CDK-activating': [1128, 2358], 'Kinase': [1129, 2359], '(CAK).': [1130, 2360], 'Landes': [1131, 2361], 'Bioscience,': [1132, 2362], 'Georgetown,': [1133, 2363], 'TX2001Google': [1134, 2364], 'investigate': [1137, 4647], 'repair,': [1145], 'cycle,': [1148], 'developed': [1150], 'system.': [1154], 'Knowing': [1155], 'can': [1161, 2559, 2891, 3328, 3898, 4575, 4836, 5119, 5142, 5730], 'stably': [1163], 'assembled,': [1164], 'for': [1170, 1337, 1567, 1920, 1952, 1959, 2539, 2898, 3087, 3134, 3742, 3881, 4058, 4571, 4586, 4663, 4683, 5405, 5409, 5733, 5761, 5775, 5790, 5797], 'fourth': [1172], 'partner,': [1173], 'detected': [1177], 'screening': [1179, 1195, 1725, 2630, 4662, 4835], 'cDNA': [1181, 1193, 1481, 1609, 1728, 2616, 4502, 4661], 'library.': [1182, 4503], 'first': [1184], 'this': [1186, 3800, 4397, 4428, 4484, 4566, 4793, 5338, 5396, 5723], 'new': [1187, 2954], 'assay': [1188, 1408, 1955, 2885, 3178, 4567], 'showing': [1190], 'library': [1194, 1724, 1729, 1742, 2617, 2905, 4834], 'identifies': [1196], 'FIR': [1207, 2819, 4686], '(far': [1208], 'upstream': [1209, 2413], 'element-binding': [1210], 'repressor),': [1212], 'regulation': [1218, 2770], 'c-Myc': [1220], 'gene': [1221, 1263, 1583, 2067, 2579, 2772, 3073, 3163, 3546], 'expression': [1222, 2499, 2530, 2580, 2773, 2997, 3035, 3074, 3150, 3547, 3626, 3876, 4806], '(21Liu': [1223, 2845, 4688], 'He': [1225, 2847, 4690], 'Collins': [1227, 2849, 4692], 'Ge': [1229, 2851, 4694, 4766], 'Libutti': [1231, 2853, 4696], 'Li': [1233, 2855, 4698], 'Levens': [1237, 2859, 4702], '5:': [1242, 2864, 4707], '331-341Abstract': [1243, 2865, 4708], '(129)': [1251, 2873, 4716], 'addition,': [1255, 2790, 4178], 'connected': [1260], 'regulation,': [1264], 'too,': [1265], 'investigated.': [1270], 'Coexpression': [1271], 'experiments': [1272], 'baculovirus-infected': [1274], 'interlinks': [1279], 'mainly': [1281, 4143, 5506], 'via': [1282, 1292, 5524, 5548], 'p44': [1294, 1320, 1808, 4173, 4228, 4280, 4369, 4437, 4452, 5070, 5529], 'subunit.': [1295], 'until': [1307], 'incorporation': [1308], 'into': [1309, 3331, 3901], 'illustrated': [1312], 'release': [1315], 'when': [1319, 3102, 3953, 3988, 4436, 4451, 4535], 'present.': [1322], 'allowed': [1324], 'architecture,': [1329], 'explain': [1330], 'phenotypes,': [1333], 'design': [1335], 'strategies': [1336], 'crystallographic': [1338], 'studies.': [1339], 'All': [1340, 1699], 'media': [1345], 'composition,': [1346], 'transformation,': [1347], 'selection': [1349, 1708], 'were': [1350, 1413, 1447, 1547, 1654, 1703, 1751, 1783, 1796, 1809, 1817, 1900, 2646, 3021, 3028, 3486, 3703, 3711, 3893], 'performed': [1351, 1414, 1744, 3048, 4318], 'described': [1353, 1416, 1448, 1669, 1701, 1820, 1969, 4680, 5401], '(22Rose': [1354], 'M.D.': [1355], 'Winston': [1356], 'Hieter': [1358], 'Methods': [1360, 1426, 1432], 'Yeast': [1362, 3026], 'Genetics:': [1363], 'A': [1364, 4660, 5481], 'Laboratory': [1365], 'Course': [1366], 'Manual.': [1367], 'Cold': [1368, 1372], 'Spring': [1369, 1373], 'Harbor': [1370], 'Laboratory,': [1371], 'Harbor,': [1374], 'NY1990Google': [1375], 'L40': [1378, 2589, 3496], 'strain': [1379, 2591], '(MATa,': [1380], 'trp1,': [1381], 'his3,': [1382], 'ade2,': [1383], 'leu2,': [1384], 'LYS::(LexAop)4-HIS3,URA3::(LexAop)8-lacZ)': [1385], '(23Holstege': [1388], 'van': [1390, 3321], 'der': [1391], 'Vliet': [1392], 'P.C.': [1393], 'Timmers': [1394], 'H.T.': [1395], '1666-1677Crossref': [1400], '(205)': [1403], 'Lift': [1406], 'filter': [1407], 'liquid': [1410, 1799, 2650, 3049, 3726], 'β-Gal': [1411, 1800, 2651, 2660, 2754, 2945, 2977, 3050, 3111, 3173, 3518, 3727, 3796, 3966, 4004], 'assays': [1412, 3051, 3723, 3728, 5599], 'previously': [1417, 1449], '(24Sandrock': [1418], 'Tirode': [1420], 'MacDonald': [1424], 'P.N.': [1425], 'Molecular': [1428], 'Biology:': [1429], 'Two-hybrid': [1430], 'System:': [1431], 'Protocols.': [1434], '177.': [1435], 'Humana': [1436], 'Press': [1437], 'Inc.,': [1438], 'Totowa,': [1439], 'NJ2001:': [1440], '271-289Google': [1441], 'pLex9-Cdk7/Met-25-cyclin': [1443, 2501, 2595], 'pVP16-XPD': [1446], '(25Tirode': [1450, 2014, 3197, 4599], 'Malaguti': [1452, 2016, 3199, 4601], 'Romero': [1454, 2018, 3201, 4603], 'Attar': [1456, 2020, 3203, 4605], 'R.': [1457, 1591, 2021, 2237, 3204, 3650, 4606, 4740, 4904], 'Camonis': [1458, 2022, 3205, 4607], '272:': [1466, 2030, 3213, 4615, 5620], '22995-22999Abstract': [1467, 2031, 3214, 4616], '(95)': [1475, 2039, 3222, 4624], 'For': [1478, 1529, 1723], 'pXPD-VP16,': [1479], 'amplified': [1485, 1614], 'chain': [1488, 1551, 1617], 'reaction': [1489, 1552, 1618], 'sense': [1492, 1534, 1621], 'primer': [1493, 1500, 1522, 1527, 1535, 1538, 1622, 1627], '5′-GCGAAGCTTATGAAGCTCAACGTGGAC-3′': [1494], '(primer': [1495, 1502], '1)': [1496], 'antisense': [1499, 1526, 1626], '5′-GATGCTCGAGTTGAGCTGCTGAGCAATCTGC-3′': [1501], '2),': [1503], 'digested': [1504], 'HindIII': [1506], 'XhoI': [1508], 'cloned': [1510, 1636], 'sites': [1514], 'pVP16.': [1516], 'pXPDN-VP16': [1517], 'made': [1519, 1576], '1': [1523, 1556, 1910, 2582, 3098, 3116, 3146, 4014], '5′-GTACCTCGAGCTGAAGTGCAGGATGGG-3′.': [1528], 'pXPDC-VP16': [1530], '5′-GTACAAGCTTATGATCCTGCACTTCAGCTGC-3′': [1536], '2.': [1539], 'mutants': [1542, 1648, 3452, 3710], 'R112H,': [1543], 'D234N,': [1544], 'G602D': [1546, 3663], 'constructed': [1548, 3022, 3448], 'amplification': [1553], 'primers': [1555], '2': [1558, 1779, 3024, 3044, 3095, 3454, 3521, 3750, 4825], 'clones': [1561, 1668, 1793, 2644, 2656, 2942, 2974, 3061], 'pACter-R112H,': [1562], 'pACter-D234N,': [1563], 'pACter-G602D,': [1565], 'baculovirus': [1568, 4314], 'transfection,': [1569], '2S.': [1570], 'Dubaele,': [1571, 5771], 'unpublished': [1572, 3815], 'results.': [1573], 'pYEA': [1574, 1642, 1712], 'replacing': [1578], 'Saccharomyces': [1580, 1604], 'cerevisiae': [1581, 1605], 'HIS3': [1582, 1771, 2066], 'YEp90': [1585], '(26Gaudon': [1586], 'Losson': [1590], '18:': [1595, 3310], '2229-2240Crossref': [1596], '(33)': [1599], 'ADE2': [1606], 'gene.': [1607, 2421], 'human': [1611, 5708], '5′-CGATGAATTCATGGACGATCAGGGTTGC-3′': [1623], '5′-GATACAGGAATTCTTAACTGGGCTGCCAGAA-3′.': [1628], 'After': [1629, 1773, 1940], 'digestion': [1630, 1664], 'withEcoRI,': [1631], 'fragment': [1634], 'EcoRI': [1639], 'obtain': [1644], 'pYEA-MAT1.': [1645, 2516, 2598], 'pYEA-MAT1': [1647], 'MAT1-(1–66),': [1649], 'MAT1-(67–189),': [1650], 'MAT1-(191–309),': [1651], 'MAT1-(67–309)': [1653, 4022], 'derived': [1655, 1730, 2618, 5738], 'insertion': [1657], 'fragments': [1661], 'obtained': [1662], 'throughEcoRI': [1663], 'pVP16': [1667, 1718], 'elsewhere': [1670, 1821, 1970], '(27Busso': [1671, 3904, 4933], 'Keriel': [1673, 1869, 2188, 2719, 3227, 3906, 4935], 'Sandrock': [1675, 1871, 2190, 2721, 3229, 3908, 4937], 'Poterszman': [1677, 1873, 2192, 2723, 3231, 3910, 4939, 5678], 'Gileadi': [1679, 1875, 2194, 2725, 3233, 3912, 4941, 5636], 'O.': [1680, 1876, 2195, 2726, 3234, 3913, 4942, 5637], '22815-22823Abstract': [1688, 1884, 2203, 2734, 3242, 3921, 4950], '(61)': [1696, 1892, 2211, 2742, 3250, 3929, 4958], 'constructs': [1700, 1706, 1713, 1719], 'above': [1702], 'sequenced.': [1704, 2664], 'PLexA-derived': [1705], 'allow': [1707, 3963, 5089], 'tryptophan-lacking': [1710], 'medium,': [1711, 1716], 'adenine-lacking': [1715], 'leucine-lacking': [1721], 'medium.': [1722, 1791, 3065], 'Matchmaker': [1727], 'HeLa': [1732, 2620, 4849], 'mRNA': [1734, 2622], '(CLONTECH)': [1735], 'used.': [1737], 'transformation': [1739], 'according': [1745], "manufacturer's": [1748], 'protocol.': [1749], 'Cells': [1750], 'grown': [1752], 'medium': [1754, 2464, 2557, 2641], 'lacking': [1755], 'tryptophan,': [1756], 'adenine,': [1757], 'leucine': [1758], 'histidine': [1760], '(TALH': [1761], 'medium)': [1762], 'containing': [1763, 2087, 3457, 3472], '20': [1764], 'mm': [1765, 1780, 1906, 1911, 1914, 1944, 3147], '3-amino-1,2,4-triazole,': [1766], 'suppressor': [1768], 'nonspecific': [1770], 'expression.': [1772], '8–10': [1774], 'days,': [1775], 'colonies': [1776], 'larger': [1777], 'than': [1778, 5569], 'diameter': [1782], 'collected': [1784], '(∼500)': [1785], 'restreaked': [1787], 'same': [1790], '109': [1792, 2643], 're-grew': [1795], 'analyzed': [1797, 4333], 'assays.': [1801], 'overexpressed': [1810, 4120], 'Sf9': [1812], 'cells,': [1813], 'extracts': [1816, 4316, 4852], 'prepared': [1818, 4312], '27Busso': [1867, 2186, 2717, 3225], '150': [1895, 1913], 'μg': [1896], 'extract': [1899], 'incubated': [1901], 'buffer': [1903, 1938], 'W': [1904], '(20': [1905], 'Tris,': [1907], '10%': [1908], 'glycerol,': [1909], 'EDTA,': [1912], 'KCl,': [1915, 1945], '0.1%': [1917], 'Nonidet': [1918], 'P-40)': [1919], '4': [1921, 1931], 'h': [1922], '10': [1924], 'μl': [1925], 'A-Sepharose-conjugated': [1928], 'antibody': [1929], 'at': [1930, 3039, 4110], '°C': [1932], 'then': [1934, 2455, 2613, 3047, 3487, 3565, 4233], 'extensively': [1935], 'washed': [1936], 'equilibration': [1941], '50': [1943], 'one-half': [1946], 'beads': [1949, 4337], 'polyacrylamide': [1960], 'gel': [1961], 'electrophoresis': [1962], 'followed': [1963], 'Western': [1965], 'blot': [1966], 'analysis': [1967], '(8Coin': [1971, 3424, 3820, 4281, 4338], 'reconstitution': [1994, 3136], 'quaternary': [1997, 2545, 2573, 3513, 3982], 'lead,': [2005], 'two-': [2010], 'three-hybrid': [2012], 'systems': [2013], '28Brachmann': [2042], 'R.K.': [2043], 'Boeke': [2044], 'J.D.': [2045], 'Biotechnol.': [2048], '8:': [2050], '561-568Crossref': [2051], 'activation': [2059, 2428, 2627], 'reporter': [2061, 2420, 2578], 'lacZgene': [2070], '(Fig.': [2071, 2581, 3023, 3094, 3453, 3520, 3705, 3746, 3967, 4072, 4134, 4391, 4465, 4824], '1).': [2072], 'took': [2074], 'advantage': [2075], 'fact': [2078, 4643], 'very': [2083, 3185], '(29Devault': [2093], 'Martinez': [2095], 'Fesquet': [2097], 'Labbé': [2099], 'Morin': [2101], 'N.': [2102, 3383, 3585, 5376], 'Tassan': [2103, 2218, 4885], 'J.P.': [2104, 2122, 2215, 2219, 2272, 4882, 4886], 'Nigg': [2105, 2131, 2220, 4887], 'E.A.': [2106, 2132, 2221, 4888], 'Cavadore': [2107], 'Dorée': [2109], '1995;': [2113, 2135, 3678], '14:': [2114, 2136], '5027-5036Crossref': [2115], '(201)': [2118], '30Tassan': [2121], 'Jaquenoud': [2123], 'Fry': [2125], 'Frutiger': [2127], 'Hughes': [2129], 'G.J.': [2130], '5608-5617Crossref': [2137], '(172)': [2140], 'exist': [2144, 4860], 'element': [2156], 'cascade.': [2161], 'As': [2162, 2756, 4360], 'such,': [2163], 'interacts': [2165, 2993, 3192], '31Adamczewski': [2214, 4881], 'Moncollin': [2222, 4889], 'V.': [2223, 3648, 4890, 5681], '1877-1884Crossref': [2230, 4897], '(114)': [2233, 4900], '32Drapkin': [2236, 4739, 4903], 'Le': [2238, 4741, 4905], 'Roy': [2239, 4742, 4906], 'G.': [2240, 3652, 4743, 4907], 'Cho': [2241, 4744, 4908], 'Akoulitchev': [2243, 4746, 4910], '93:': [2255, 4758, 4784, 4922], '6488-6493Crossref': [2256, 4759, 4923], '(140)': [2259, 4762, 4926], 'cyclin-dependent': [2264], 'kinases': [2265], '(Cdc2': [2266], '(33Poon': [2267], 'R.Y.C.': [2268], 'Yamashita': [2269], 'Adamczewski': [2271], 'Hunt': [2273], 'Shuttleworth': [2275], '1993;': [2279], '12:': [2280], '3123-3132Crossref': [2281], '(333)': [2284], 'Cdk2': [2287], '(34Fisher': [2288], 'R.P.': [2289], 'Morgan': [2290], 'D.O.': [2291], '78:': [2294], '713-724Abstract': [2295], '(560)': [2301], 'Cdk4': [2304], '(35Kato': [2305], 'J.Y.': [2306], 'Matsuoka': [2307], 'Polyak': [2309], 'Massague': [2311], 'Sherr': [2313], 'C.J.': [2314], '79:': [2317], '487-496Abstract': [2318], '(709)': [2324], 'Scholar))': [2326, 3702], 'substrates': [2330, 5202], 'like': [2331], 'receptors': [2333, 5210], 'p53': [2335], '(Ref.': [2336], 'and36Ko': [2366], 'L.J.': [2367], 'Shieh': [2368], 'S.Y.': [2369], 'Chen': [2370, 3298], 'X.': [2371, 5607], 'Jayaraman': [2372], 'Tamai': [2374], 'Taya': [2376], 'Y.': [2377, 3692], 'Prives': [2378], 'Pan': [2380, 4774], 'Z.Q.': [2381], '7220-7229Crossref': [2387], '(149)': [2390], 'Scholar': [2392], 'references': [2394], 'therein).': [2395], 'Therefore': [2396, 2996, 5662], 'fused': [2401, 2425, 2623, 3006, 3989, 4809], '(here,': [2407, 2430], 'LexA-Cdk7),': [2408], 'recognizes': [2410, 4510], 'sequence': [2414], 'promoter': [2417, 2512, 2832], 'Another': [2422], 'X-VP16),': [2431], 'interact': [2434, 2824, 5593], 'basal': [2437], 'machinery.': [2439], 'direct': [2441], '(two-hybrid)': [2442], 'mediated': [2445, 4218], '(three-': [2446], 'four-hybrid)': [2448], 'fusion': [2453, 2491], 'allows': [2456, 3517, 4819], 'growth': [2458], 'histidine-lacking': [2463], 'detection': [2467], 'activity.': [2470, 3624, 4479, 5085, 5469], 'Thus,': [2471], 'expressed': [2486, 3488, 3712], 'independently': [2487], 'proteins.': [2492, 2814, 4659], 'Cyclin': [2493], 'conditional': [2498], 'vector': [2500], 'control': [2507, 2538, 4533], 'phosphoglycerate': [2510], 'plasmid': [2515], 'has': [2518, 2820, 3529, 4638, 4670, 5399, 5558, 5579, 5589], 'pointed': [2521, 3532], 'out': [2522, 3533, 4831], 'Met-25': [2525, 2550], 'promoter,': [2526, 2551], 'serves': [2535], 'checking': [2540], 'specificity': [2542, 4559], 'assembly.': [2547], 'active': [2554], 'normal': [2556], 'conditions,': [2558, 4506], 'repressed': [2561], 'presence': [2564, 3057, 3068, 3129, 3144], 'methionine,': [2566, 3148], 'consequently': [2576, 5184], 'B).': [2583, 3025], 'sequentially': [2586, 3029], 'transformed': [2587, 3030], 'plasmids': [2594], '(including': [2604], 'MAT1)': [2609], 'screened': [2614], 'VP16': [2626, 3003, 4808], 'domain.': [2628, 3947, 5551], 'Double': [2629], 'transformants': [2634], '(1.5': [2635], 'million)': [2636], 'plating': [2638], 'TALH': [2640], 'gave': [2642], 'positive': [2647], 'assay.': [2652], 'Eighteen': [2653], 'highest': [2659, 2753], 'been': [2663, 2821, 4639, 4679, 5400, 5443, 5559, 5590, 5719], 'surprise': [2667], 'helicase,': [2672], 'core-TFIIH': [2677], '12Rossignol': [2701], 'activities.': [2755], 'listed': [2757, 2936, 2968], 'Table': [2759], 'I,': [2760], 'found': [2763, 3570, 3634], '(HSP60,': [2774], 'hoxC10,': [2775], 'pRB-binding': [2776], 'polypeptide': [2779], '1a': [2782, 2914], '(eEF-1),': [2783], 'FIR,': [2784], 'SR': [2786], 'splicing': [2787, 2917], 'factor).': [2788], 'different': [2795], 'proteasome': [2796], 'calcium-dependent': [2800], 'protease': [2801], 'members': [2803], 'degradation': [2806], 'pathways': [2807], 'still': [2812, 4034], 'unknown': [2813], 'Up': [2815], 'now': [2817, 4963, 5001], 'shown': [2822, 4275, 5560, 5591], 'resulting': [2827], 'repression': [2830], 'escape': [2833], 'activated': [2840], 'before': [2841], 'protein)': [2844], 'findings': [2877], 'fit': [2878], 'previous': [2880, 4931], 'reports': [2881], 'validate': [2883, 2984], 'screen': [2897, 2934, 2966, 4500, 4585, 4798], 'partners.Table': [2900], 'IcDNAs': [2901], 'screeningcDNANo.': [2906], 'clonesβ-GalXPD1100HoxC101120FIR379pRB-binding': [2908], 'II355Proteasome': [2910], 'subunit152Polypeptide': [2911], '(eEF-1)247Calcium-dependent': [2915], 'protease147SR': [2916], 'factor129Proteasome': [2918], 'subunit228HSP60': [2919], '(heat': [2920], 'shock': [2921], 'protein)125Unknown': [2922], 'A5139Unknown': [2923], 'B21122VP162The': [2924], 'names': [2925, 2957], 'cDNAs': [2928, 2960], 'together': [2937, 2969, 3123, 3489, 3715, 4027, 4421], 'number': [2940, 2972], '(XPD': [2947, 2979], '=': [2948, 2980], '100%).': [2949, 2981], 'Open': [2950], 'table': [2951], 'tab': [2955], 'assay,': [2986, 4628], 'investigated': [2988, 3277], 'how': [2989, 4832, 5003], 'CAK.': [2995, 3283, 4981], 'vectors': [2998, 3036, 3627], 'activating': [3002], 'C': [3010, 3997, 4812, 5520], 'terminus': [3011, 3017, 3998, 4813, 5521], '(XPD-VP16)': [3012, 4818], 'N': [3016], '(VP16-XPD)': [3018], 'combination': [3033, 4099], 'indicated': [3038, 4109], 'bottom': [3041], 'Fig.': [3043, 4114], 'absence': [3054, 5364], 'methionine': [3059], 'growing': [3062], 'TAL': [3064], 'VP16-XPD,': [3070], 'no': [3071, 3110], 'lacZ': [3072, 3162], 'occurs,': [3075], 'indicating': [3076], 'availability': [3079], 'moiety': [3084, 3505], 'crucial': [3086, 3880], 'A,': [3096, 3522, 3871, 4371, 4407], 'lanes': [3097, 3523, 3749, 3969, 4372, 4394, 4441, 4468], '3).': [3100, 4075], 'Moreover,': [3101, 5086], 'expressed,': [3109, 4544], 'synthesized': [3113], '(compare': [3114, 4440], 'lane': [3115, 3872, 4074, 4408], 'withlanes': [3117], '5': [3118, 4115, 4135, 4392, 4466], '7,': [3120], 'respectively).': [3121, 3526], 'Taken': [3122], 'results': [3125, 3790], 'indicate': [3126], 'necessary': [3133, 4057], 'transcriptional': [3139, 4040, 5436], 'activator.': [3140], 'Finally,': [3141], 'inhibited,': [3155], 'therefore,': [3157, 3617, 3972], 'product': [3164], 'significantly': [3166], 'reduced': [3167], '(lane': [3168, 4042, 4152, 4175, 4414, 4424], '2).': [3169], 'However,': [3170], 'synthesis': [3174, 3519, 3964], 'could': [3179, 3771, 4236, 4630, 5046], 'result': [3180], 'unstable': [3186], 'Cdk7·MAT1·XPD': [3187], 'since': [3189], 'weakly': [3191], 'Since': [3253], 'major': [3261], 'players': [3262], 'NER,': [3264], 'lead': [3268, 4002, 5047], 'XP,': [3270], 'trichothiodystrophy': [3274], 'diseases,': [3275], 'targets': [3282, 4682], 'Three-dimensional': [3284], 'models': [3285], 'designed': [3290, 3704, 4488], 'UVRB': [3295], '(37Theis': [3296], 'P.J.': [3299], 'Skorvaga': [3300], 'Van': [3302], 'Houten': [3303], 'Kisker': [3305], '6899-6907Crossref': [3311], '(165)': [3314], '3R.': [3317], 'Bienstock': [3318], 'Houtten,': [3322], 'personal': [3323], 'communication.': [3324], 'divided': [3330], 'domains,': [3333, 3952], 'domain,': [3336, 3347, 3809, 3937, 3941], 'includes': [3338], 'elements': [3341], '(Fig.3': [3342], 'A),': [3343, 4826], 'C-terminal': [3346, 3474, 3538, 3944, 4051], '80%': [3350], 'seen': [3354], 'patients': [3357, 3573, 3637], 'located': [3359], '(11Lehmann': [3360], '38Taylor': [3372], 'Broughton': [3374, 3576], 'Botta': [3376, 3578], 'Stefanini': [3378, 3580, 3670], 'Sarasin': [3380, 3582], 'Jaspers': [3382, 3584], 'Fawcett': [3384, 3586], 'Harcourt': [3386, 3588], 'Arlett': [3388, 3590], 'Lehmann': [3390, 3592, 3668], '94:': [3400, 3602], '8658-8663Crossref': [3401, 3603], '(240)': [3404, 3606], 'Some': [3407], 'them': [3409], 'weaken': [3410, 3736], 'thereby': [3415], 'inhibiting': [3416], 'holo-TFIIH': [3423, 5542], 'Therefore,': [3446], 'deletion': [3451], 'B),': [3455], 'half': [3460, 3475], 'central': [3463], '(amino': [3465, 3478], 'acids': [3466, 3479], '1–436,': [3467], 'XPDN-VP16)': [3468], '431–760,': [3480], 'XPDC-VP16).': [3481], 'XPDN-VP16': [3482, 3516, 4026], 'XPDC-VP16': [3484], 'strain.': [3498], 'XPDC-VP16,': [3499], 'lacks': [3501], '1–430': [3503], 'prevents': [3508], 'whereas': [3515, 5518], '13': [3524], 'and11,': [3525], 'Nevertheless,': [3527, 5445], 'truncation': [3535], 'partially': [3542, 4037], 'affects': [3543, 3817], 'optimal': [3545, 4478], 'induction': [3548], '(around': [3549], '70%': [3550], 'compared': [3551], 'XPD-wild': [3553], 'type),': [3554], 'underlying': [3555], 'importance': [3557], 'preserved': [3561], 'architecture.': [3563], 'wondered': [3566], 'if': [3567, 5451, 5711], '(38Taylor': [3574], 'CAK-XPD': [3615, 5453], 'Fused': [3625], 'bearing': [3628], 'identical': [3631], 'those': [3633, 3956], '(R112H': [3638], '(39Stefanini': [3639], 'Giliani': [3641], 'Nardo': [3643], 'Nazzaro': [3647], 'Rizzo': [3649], 'Trevisan': [3651], 'Mutat.': [3653], '273:': [3656], '119-125Crossref': [3657], '(63)': [3660], '(40Takayama': [3664], 'Salazar': [3666], 'E.P.': [3667], 'Thompson': [3672], 'L.H.': [3673], 'Weber': [3674], 'C.A.': [3675], 'Cancer': [3676], '5656-5663PubMed': [3680], 'D234N': [3684], '(41Ichihashi': [3685], 'Yamamura': [3687], 'Hiramoto': [3689], 'Fujiwara': [3691], 'Arch.': [3693], 'Dermatol.': [3694], '1988;': [3695], '124:': [3696], '256-260Crossref': [3697], '(29)': [3700], '3': [3706, 3747], 'A).': [3707], 'hybrid': [3709], 'MAT1.': [3721, 5174], 'Lift-filter': [3722], 'combined': [3724], 'XPD-R112H': [3731], 'XPD-D234N': [3735], 'capacity': [3739], 'B,': [3748, 4393, 4467], 'and4).': [3751], 'Together': [3752, 4929], 'data': [3754, 5088], 'suggest': [3755], 'targeted': [3763], 'due': [3773, 5121, 5418, 5432], 'defect': [3776], 'interactions.': [3779, 4243], 'is,': [3781], 'however,': [3782], 'interesting': [3783], 'note': [3785], 'XPD-G602D': [3788, 4070], 'mutation': [3789], '40%': [3793], 'drop': [3794], 'activity,': [3797, 5009], 'meaning': [3798], 'mutation,': [3801], 'XPD/p44-interacting': [3808], '4B.': [3810], 'Sandrock,': [3811], 'Egly,': [3814], 'data.': [3816], '42Seroz': [3842], 'Perez': [3844], 'Bergmann': [3846], 'Bradsher': [3848], '33260-33266Abstract': [3857], '(37)': [3865], 'Having': [3868], '(Fig.2': [3870], '7)': [3873], 'CAK-XPD,': [3886], 'asked': [3888, 4234], 'parts': [3890], 'critical': [3894, 5762], 'domains.': [3896], 'subdivided': [3900], 'regions': [3903], 'ring': [3934], 'finger': [3935], '(MAT1-(1–66))': [3936], '(MAT1-(67–189))': [3940], '(MAT1-(191–309))': [3946], 'None': [3948], 'transfected': [3954], 'expressing': [3957], '4,': [3968], '1–5)': [3970], 'sufficient': [3975], 'promote': [3977], 'On': [3984], 'hand,': [3987], 'together,': [3990], '(MAT1-(67–309))': [4001], 'comparable': [4006], 'entire': [4011], '(lanes': [4013, 4167, 4202], '6).': [4016], 'noted': [4020], 'truncated': [4025], 'LexA-Cdk7': [4029], 'able': [4035], 'reconstitute': [4038], 'activator': [4041, 4823], '7).': [4043], 'demonstrates': [4045], 'motifs': [4048], 'assembly,': [4062], 'point': [4064], 'already': [4065, 4678], 'suggested': [4066], 'transfection': [4068], '3,': [4073], 'architecture': [4080, 5664], 'especially': [4084], 'subcomplex,': [4089], 'insect': [4092], 'baculoviruses': [4095], 'overexpressing': [4096], 'top': [4112], 'antibodies': [4123, 4181, 4322], 'directed': [4124, 4182], 'against': [4126, 4183, 4323], 'immunoprecipitate': [4130], 'all': [4131, 4840, 5743], 'four': [4132], 'A,lanes': [4136], '2,': [4137], '5,': [4138], '17).': [4140, 4425], 'occurs': [4144, 4399], '13)': [4153], 'maintained': [4156], '16': [4168], '17)': [4170], '15).': [4176], 'immunoprecipitations': [4179, 4319], 'reveal': [4188], 'CAK·XPD·p44': [4190], 'Note': [4192], 'each': [4194, 4200, 4833], 'stoichiometric': [4197], 'amounts': [4198], '6,': [4203], '9,': [4204], '18).': [4206, 4444], 'strongly': [4208], 'shows': [4209, 5002], 'anchoring': [4212], 'binds': [4222, 5507], 'side,': [4226], 'other.': [4231], 'what': [4235, 4986], 'biological': [4239, 4988], 'significance': [4240, 4989], 'main': [4245], '5′-3′': [4256, 4363], 'unwinding': [4257, 5050], 'damage,': [4269], 'respectively,': [4270], 'stimulated': [4278, 4367], 'analyze': [4304, 4579, 4800], 'effect': [4306, 5076], 'AbXPD': [4321], 'XPD-containing': [4324], 'complexes.': [4325, 4802], 'expected,': [4361], '(Fig.5': [4370, 4406], '12': [4373], '14).': [4375], 'surprise,': [4378], 'substantially': [4385], 'diminishes': [4386], '3–5).': [4395], 'alone': [4405], '13),': [4409], 'carried': [4410, 4417], '16)': [4415], 'More': [4426], 'importantly,': [4427], 'relieved': [4433], '(or': [4434], 'prevented)': [4435], 'present': [4439, 5471], '13,15,': [4442], 'worth': [4448], 'mentioning': [4449], 'bound': [4454], 'does': [4458], 'inhibit': [4460], '6–8).': [4469], 'explains': [4471], 'why': [4472], 'exhibits': [4476], 'its': [4477, 4530, 4656, 5041, 5105, 5160, 5461, 5467, 5519, 5549], 'course': [4482], 'study': [4485, 5000, 5397, 5472], 'any': [4501, 5052], 'Under': [4504], 'more': [4514], 'specifically': [4515], 'attachment.': [4518], 'Our': [4519, 4999], 'system,': [4520], 'uses': [4522], 'possesses': [4529, 5006], 'own': [4531], 'since,': [4534], '(cyclin': [4540], 'H)': [4541], 'cannot': [4548], 'formed.': [4550], 'improvement': [4555], 'strength': [4562], 'interaction,': [4565], 'flexible': [4570], 'additional': [4572], 'approaches;': [4573], 'structural': [4580], '(MAT1)': [4582], 'inhibitors,': [4594], 'hinder': [4596], 'adapted': [4632], 'once': [4633, 5109], 'identified,': [4640], 'set': [4644], 'up': [4645], 'putative': [4657], 'CAK-interacting': [4664], 'others': [4675], 'Scholar,43Reardon': [4764], 'J.T.': [4765], 'Gibbs': [4768], 'Sancar': [4770], 'Hurwitz': [4772], 'Z.-Q.': [4775], '6482-6487Crossref': [4785], '(99)': [4788], 'validates': [4792], 'highly': [4794], 'method': [4796], 'Because': [4803], 'points': [4830], 'fail': [4837], 'possible': [4841], 'partners.': [4843], 'definitively': [4964], 'established': [4965], 'bridges': [4968], 'However': [4982], 'unclear': [4985], 'transcription.': [4998], 'switched': [5011, 5458], 'off': [5012, 5030, 5459], 'rendering': [5018], 'unable': [5022], 'unwind': [5024], 'DNA.': [5025], 'ability': [5027], 'switch': [5029], 'avoids': [5032], 'deregulated': [5034], 'apart': [5039], 'linked': [5055], 'proper': [5057], 'reactions.': [5061], 'Upon': [5062], 'CAK·XPD,': [5069], 'counteracts': [5073], 'repressive': [5075], 'stimulates': [5081], 'whether': [5094], 'exists': [5098], 'cell,': [5102], 'recovers': [5104], 'associates': [5111], 'inhibition,': [5117], 'conformational': [5124], 'changes': [5125], 'induced': [5126], 'mask': [5131], 'ATP': [5137], 'circumvented': [5144], 'p44.': [5146], 'leading': [5164], 'appearance': [5167], 'phenotype,': [5170], 'weaker': [5177], '(and': [5183], 'CAK)': [5185], 'disturb': [5188], 'toward': [5201], 'II': [5207], '16Rochette-Egly': [5234], '44Chen': [5286], 'Washbrook': [5290], 'Pace': [5292], 'P.E.': [5293], 'Coombes': [5294], 'Ali': [5298], '127-137Abstract': [5304], '(253)': [5312], '45Lee': [5315], 'D.K.': [5316], 'Duan': [5317], 'H.O.': [5318], 'Chang': [5319], '9308-9313Abstract': [5326], '(89)': [5334], 'latter': [5339], 'case': [5340], 'observe': [5343], 'defects': [5344], 'hormonal': [5347], 'responses.': [5348], 'With': [5349], 'respect': [5350], 'this,': [5352], 'recent': [5354], 'observation': [5355], 'adult': [5357], 'knock-out': [5358], 'mice': [5359], 'viable': [5361], 'needs': [5367], 'clarified': [5370], '(46Rossi': [5371], 'D.J.': [5372], 'Londesborough': [5373], 'Korsisaari': [5375], 'Pihlak': [5377], 'Lehtonen': [5379], 'Henkemeyer': [5381], 'Makela': [5383], 'T.P.': [5384], '2844-2856Crossref': [5389], '(83)': [5392], 'essential': [5404], 'early': [5406], 'embryonic': [5407], 'development': [5408], 'trophoblast': [5413], 'giant': [5414], 'cells.': [5415], 'inability': [5421], 'trophoectodermal': [5423], 'enter': [5426], 'S': [5428], 'phase': [5429], 'general': [5435], 'defect,': [5437], 'although': [5438], 'hormone-regulated': [5439], 'analyzed.': [5444], 'remains': [5447], 'determined': [5450], 'sheds': [5474], 'light': [5475], 'MAT1·XPD·p44': [5482], 'kind': [5486], 'hinge': [5488], 'organized': [5499], '(Fig.6).': [5500], 'integrated': [5523], 'core-TFIIH.': [5532], 'outermost': [5539], 'stabilized': [5545], 'Tfb3,': [5552], 'counterpart': [5555], 'yTFIIH': [5567], 'TFIIK,': [5570], 'Kin28/Cdk7': [5574], 'Ccl1/cyclin': [5576], 'Tfb3': [5578], 'privileged': [5582], 'Rad3,': [5584], 'ortholog,': [5587], 'Kin28': [5595], '(47Feaver': [5600], 'W.J.': [5601, 5633], 'Henry': [5602], 'N.L.': [5603], 'Wang': [5604], 'Z.': [5605], 'Wu': [5606], 'Svejstrup': [5608], 'Bushnell': [5610], 'D.A.': [5611], 'Friedberg': [5612, 5644], 'E.C.': [5613, 5645], 'Kornberg': [5614, 5642], '19319-19327Abstract': [5621], '(62)': [5629], '48Feaver': [5632], 'Huang': [5634], 'Myers': [5638], 'Gustafsson': [5640], 'C.M.': [5641], '5941-5946Abstract': [5651], '(21)': [5659], 'MAT1/Tfb3': [5666], 'fits': [5667], 'perfectly': [5668], 'electron': [5671], 'microscopy': [5672], 'image': [5673], '(49Schultz': [5674], 'Mallouh': [5680], 'Moras': [5682], '102:': [5688], '599-607Abstract': [5689], '(167)': [5697], 'similar': [5704], 'even': [5710], 'relative': [5713], 'affinities': [5714], 'evolved': [5720], 'differently.': [5721], 'Finally': [5722], 'model': [5724], 'provide': [5726], 'useful': [5727], 'information': [5728], 'investigations': [5735], 'crystals': [5737], 'indebted': [5752], 'Mohan,': [5755], 'Bradsher,': [5757], 'Bell': [5760], 'reading': [5763], 'manuscript': [5766], 'Tirode,': [5769], 'Kwon': [5774], 'fruitful': [5776], 'discussions': [5777], 'advice.': [5779], 'grateful': [5782], 'Weickert': [5789], 'recombinant': [5791], 'production': [5793], 'Vicaire': [5796], 'sequencing.': [5798]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1973201073', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 6}], 'updated_date': '2024-12-14T14:59:03.801321', 'created_date': '2016-06-24'}