Conversion of <i>Xenopus</i> Ectoderm into Neurons by NeuroD, a Basic Helix-Loop-Helix Protein

Name: Work Video:
Duration: 3 min 30 s
Jacqueline E. Lee; Stanley M. Hollenberg; Lauren Snider; David L. Turner; Naomi Lipnick; Harold Weintraub
{'id': 'https://openalex.org/W1972676659', 'doi': 'https://doi.org/10.1126/science.7754368', 'title': 'Conversion of <i>Xenopus</i> Ectoderm into Neurons by NeuroD, a Basic Helix-Loop-Helix Protein', 'display_name': 'Conversion of <i>Xenopus</i> Ectoderm into Neurons by NeuroD, a Basic Helix-Loop-Helix Protein', 'publication_year': 1995, 'publication_date': '1995-05-12', 'ids': {'openalex': 'https://openalex.org/W1972676659', 'doi': 'https://doi.org/10.1126/science.7754368', 'mag': '1972676659', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7754368'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1126/science.7754368', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S3880285', 'display_name': 'Science', 'issn_l': '0036-8075', 'issn': ['0036-8075', '1095-9203'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315823', 'host_organization_name': 'American Association for the Advancement of Science', 'host_organization_lineage': ['https://openalex.org/P4310315823'], 'host_organization_lineage_names': ['American Association for the Advancement of Science'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5057658936', 'display_name': 'Jacqueline E. Lee', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210089486', 'display_name': 'Fred Hutch Cancer Center', 'ror': 'https://ror.org/007ps6h72', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210089486']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jacqueline E. Lee', 'raw_affiliation_strings': ['Fred Hutchinson Cancer Research Center, Seattle, WA 98104, USA.'], 'affiliations': [{'raw_affiliation_string': 'Fred Hutchinson Cancer Research Center, Seattle, WA 98104, USA.', 'institution_ids': ['https://openalex.org/I4210089486']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055447450', 'display_name': 'Stanley M. Hollenberg', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I165690674', 'display_name': 'Oregon Health & Science University', 'ror': 'https://ror.org/009avj582', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I165690674']}, {'id': 'https://openalex.org/I4210089486', 'display_name': 'Fred Hutch Cancer Center', 'ror': 'https://ror.org/007ps6h72', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210089486']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Stanley M. Hollenberg', 'raw_affiliation_strings': ['Fred Hutchinson Cancer Research Center, Seattle, WA 98104, USA.', 'Oregon Health and Science University'], 'affiliations': [{'raw_affiliation_string': 'Oregon Health and Science University', 'institution_ids': ['https://openalex.org/I165690674']}, {'raw_affiliation_string': 'Fred Hutchinson Cancer Research Center, Seattle, WA 98104, USA.', 'institution_ids': ['https://openalex.org/I4210089486']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026181369', 'display_name': 'Lauren Snider', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}, {'id': 'https://openalex.org/I4210089486', 'display_name': 'Fred Hutch Cancer Center', 'ror': 'https://ror.org/007ps6h72', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210089486']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Lauren Snider', 'raw_affiliation_strings': ['Fred Hutchinson Cancer Research Center, Seattle, WA 98104, USA.', 'Howard Hughes Medical Institute.'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute.', 'institution_ids': ['https://openalex.org/I1344073410']}, {'raw_affiliation_string': 'Fred Hutchinson Cancer Research Center, Seattle, WA 98104, USA.', 'institution_ids': ['https://openalex.org/I4210089486']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103639615', 'display_name': 'David L. Turner', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210089486', 'display_name': 'Fred Hutch Cancer Center', 'ror': 'https://ror.org/007ps6h72', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210089486']}, {'id': 'https://openalex.org/I4210113153', 'display_name': 'Neuroscience Institute', 'ror': 'https://ror.org/0240rwx68', 'country_code': 'IT', 'type': 'facility', 'lineage': ['https://openalex.org/I4210113153', 'https://openalex.org/I4210155236']}], 'countries': ['IT', 'US'], 'is_corresponding': False, 'raw_author_name': 'David L. Turner', 'raw_affiliation_strings': ['Fred Hutchinson Cancer Research Center, Seattle, WA 98104, USA.', 'Molecular and Behavioral Neuroscience Institute'], 'affiliations': [{'raw_affiliation_string': 'Fred Hutchinson Cancer Research Center, Seattle, WA 98104, USA.', 'institution_ids': ['https://openalex.org/I4210089486']}, {'raw_affiliation_string': 'Molecular and Behavioral Neuroscience Institute', 'institution_ids': ['https://openalex.org/I4210113153']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038534165', 'display_name': 'Naomi Lipnick', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210089486', 'display_name': 'Fred Hutch Cancer Center', 'ror': 'https://ror.org/007ps6h72', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210089486']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Naomi Lipnick', 'raw_affiliation_strings': ['Fred Hutchinson Cancer Research Center, Seattle, WA 98104, USA.'], 'affiliations': [{'raw_affiliation_string': 'Fred Hutchinson Cancer Research Center, Seattle, WA 98104, USA.', 'institution_ids': ['https://openalex.org/I4210089486']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5113590900', 'display_name': 'Harold Weintraub', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210089486', 'display_name': 'Fred Hutch Cancer Center', 'ror': 'https://ror.org/007ps6h72', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210089486']}, {'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Harold Weintraub', 'raw_affiliation_strings': ['Fred Hutchinson Cancer Research Center, Seattle, WA 98104, USA.', 'Howard Hughes Medical Institute.'], 'affiliations': [{'raw_affiliation_string': 'Fred Hutchinson Cancer Research Center, Seattle, WA 98104, USA.', 'institution_ids': ['https://openalex.org/I4210089486']}, {'raw_affiliation_string': 'Howard Hughes Medical Institute.', 'institution_ids': ['https://openalex.org/I1344073410']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 27.339, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 1028, 'citation_normalized_percentile': {'value': 0.999967, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '268', 'issue': '5212', 'first_page': '836', 'last_page': '844'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10268', 'display_name': 'Developmental Biology and Gene Regulation', 'score': 0.997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10268', 'display_name': 'Developmental Biology and Gene Regulation', 'score': 0.997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10423', 'display_name': 'Neurobiology and Insect Physiology Research', 'score': 0.9955, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12061', 'display_name': 'Axon Guidance and Neuronal Signaling', 'score': 0.9925, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/neurod', 'display_name': 'NeuroD', 'score': 0.99847776}, {'id': 'https://openalex.org/keywords/proneural-genes', 'display_name': 'Proneural genes', 'score': 0.65519446}], 'concepts': [{'id': 'https://openalex.org/C2778994924', 'wikidata': 'https://www.wikidata.org/wiki/Q7002104', 'display_name': 'NeuroD', 'level': 4, 'score': 0.99847776}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.78185177}, {'id': 'https://openalex.org/C2779329299', 'wikidata': 'https://www.wikidata.org/wiki/Q272474', 'display_name': 'Ectoderm', 'level': 4, 'score': 0.77348447}, {'id': 'https://openalex.org/C4746552', 'wikidata': 'https://www.wikidata.org/wiki/Q1456827', 'display_name': 'Neurogenesis', 'level': 2, 'score': 0.76588315}, {'id': 'https://openalex.org/C2779535977', 'wikidata': 'https://www.wikidata.org/wiki/Q1342298', 'display_name': 'Xenopus', 'level': 3, 'score': 0.68036616}, {'id': 'https://openalex.org/C129189402', 'wikidata': 'https://www.wikidata.org/wiki/Q17165234', 'display_name': 'Proneural genes', 'level': 4, 'score': 0.65519446}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5349131}, {'id': 'https://openalex.org/C148738053', 'wikidata': 'https://www.wikidata.org/wiki/Q210861', 'display_name': 'Cellular differentiation', 'level': 3, 'score': 0.34038478}, {'id': 'https://openalex.org/C196843134', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryo', 'level': 2, 'score': 0.2931169}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.2776451}, {'id': 'https://openalex.org/C87073359', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryogenesis', 'level': 3, 'score': 0.2201998}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.18592495}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.17434764}], 'mesh': [{'descriptor_ui': 'D002454', 'descriptor_name': 'Cell Differentiation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D004475', 'descriptor_name': 'Ectoderm', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': True}, {'descriptor_ui': 'D018257', 'descriptor_name': 'Helix-Loop-Helix Motifs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009419', 'descriptor_name': 'Nerve Tissue Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051792', 'descriptor_name': 'Basic Helix-Loop-Helix Transcription Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015816', 'descriptor_name': 'Cell Adhesion Molecules, Neuronal', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D015816', 'descriptor_name': 'Cell Adhesion Molecules, Neuronal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002454', 'descriptor_name': 'Cell Differentiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003001', 'descriptor_name': 'Cloning, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004475', 'descriptor_name': 'Ectoderm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018507', 'descriptor_name': 'Gene Expression Regulation, Developmental', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018257', 'descriptor_name': 'Helix-Loop-Helix Motifs', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009419', 'descriptor_name': 'Nerve Tissue Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D009419', 'descriptor_name': 'Nerve Tissue Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D009419', 'descriptor_name': 'Nerve Tissue Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009420', 'descriptor_name': 'Nervous System', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D009420', 'descriptor_name': 'Nervous System', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': False}, {'descriptor_ui': 'D009420', 'descriptor_name': 'Nervous System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009432', 'descriptor_name': 'Neural Crest', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D009432', 'descriptor_name': 'Neural Crest', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016415', 'descriptor_name': 'Sequence Alignment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014981', 'descriptor_name': 'Xenopus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1126/science.7754368', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S3880285', 'display_name': 'Science', 'issn_l': '0036-8075', 'issn': ['0036-8075', '1095-9203'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315823', 'host_organization_name': 'American Association for the Advancement of Science', 'host_organization_lineage': ['https://openalex.org/P4310315823'], 'host_organization_lineage_names': ['American Association for the Advancement of Science'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7754368', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 101, 'referenced_works': ['https://openalex.org/W125898244', 'https://openalex.org/W147102043', 'https://openalex.org/W1561361829', 'https://openalex.org/W1563545224', 'https://openalex.org/W1643332474', 'https://openalex.org/W1676377677', 'https://openalex.org/W1874287342', 'https://openalex.org/W1920825899', 'https://openalex.org/W1926789599', 'https://openalex.org/W1945116336', 'https://openalex.org/W1962161425', 'https://openalex.org/W1967192173', 'https://openalex.org/W1967983448', 'https://openalex.org/W1968561263', 'https://openalex.org/W1973095653', 'https://openalex.org/W1973546377', 'https://openalex.org/W1973706463', 'https://openalex.org/W1974127849', 'https://openalex.org/W1974521227', 'https://openalex.org/W1974543599', 'https://openalex.org/W1977186059', 'https://openalex.org/W1977350867', 'https://openalex.org/W1982630660', 'https://openalex.org/W1991647220', 'https://openalex.org/W1994142801', 'https://openalex.org/W1994639320', 'https://openalex.org/W1995819749', 'https://openalex.org/W2001826642', 'https://openalex.org/W2002353171', 'https://openalex.org/W2002805499', 'https://openalex.org/W2005462392', 'https://openalex.org/W2006803248', 'https://openalex.org/W2007038051', 'https://openalex.org/W2007339100', 'https://openalex.org/W2010206624', 'https://openalex.org/W2010803885', 'https://openalex.org/W2017438273', 'https://openalex.org/W2018485286', 'https://openalex.org/W2019673480', 'https://openalex.org/W2019855402', 'https://openalex.org/W2020945977', 'https://openalex.org/W2021124874', 'https://openalex.org/W2029142481', 'https://openalex.org/W2031477075', 'https://openalex.org/W2033418096', 'https://openalex.org/W2037097175', 'https://openalex.org/W2038158007', 'https://openalex.org/W2040763048', 'https://openalex.org/W2043408306', 'https://openalex.org/W2044845657', 'https://openalex.org/W2047165320', 'https://openalex.org/W2054564802', 'https://openalex.org/W2056050429', 'https://openalex.org/W2056069458', 'https://openalex.org/W2059242713', 'https://openalex.org/W2061183445', 'https://openalex.org/W2061656021', 'https://openalex.org/W2062652610', 'https://openalex.org/W2068043546', 'https://openalex.org/W2069598734', 'https://openalex.org/W2072527350', 'https://openalex.org/W2077390533', 'https://openalex.org/W2078718449', 'https://openalex.org/W2080592158', 'https://openalex.org/W2080621037', 'https://openalex.org/W2081424815', 'https://openalex.org/W2082670705', 'https://openalex.org/W2084725646', 'https://openalex.org/W2085206941', 'https://openalex.org/W2085672851', 'https://openalex.org/W2087126781', 'https://openalex.org/W2091223115', 'https://openalex.org/W2095416319', 'https://openalex.org/W2103135496', 'https://openalex.org/W2103735500', 'https://openalex.org/W2107358101', 'https://openalex.org/W2108490725', 'https://openalex.org/W2110074960', 'https://openalex.org/W2119121495', 'https://openalex.org/W2125619554', 'https://openalex.org/W2128678520', 'https://openalex.org/W2129978661', 'https://openalex.org/W2130514122', 'https://openalex.org/W2134721282', 'https://openalex.org/W2139556530', 'https://openalex.org/W2142193899', 'https://openalex.org/W2143759777', 'https://openalex.org/W2143965788', 'https://openalex.org/W2152406405', 'https://openalex.org/W2158499654', 'https://openalex.org/W2171761381', 'https://openalex.org/W2181352214', 'https://openalex.org/W2205083200', 'https://openalex.org/W2218155072', 'https://openalex.org/W2409999542', 'https://openalex.org/W2418123661', 'https://openalex.org/W4233541006', 'https://openalex.org/W4239927990', 'https://openalex.org/W4243279772', 'https://openalex.org/W4320801100', 'https://openalex.org/W638406814'], 'related_works': ['https://openalex.org/W2159549191', 'https://openalex.org/W2098867949', 'https://openalex.org/W2096701179', 'https://openalex.org/W2083680504', 'https://openalex.org/W2059879418', 'https://openalex.org/W2054920794', 'https://openalex.org/W2019132808', 'https://openalex.org/W1990510025', 'https://openalex.org/W1965648790', 'https://openalex.org/W1636380248'], 'abstract_inverted_index': {'Basic': [0], 'helix-loop-helix': [1], '(bHLH)': [2], 'proteins': [3], 'are': [4], 'instrumental': [5], 'in': [6, 36, 41, 64, 111, 135], 'determining': [7], 'cell': [8], 'type': [9], 'during': [10, 140], 'development.': [11, 143], 'A': [12], 'bHLH': [13], 'protein,': [14], 'termed': [15], 'NeuroD,': [16], 'for': [17, 28], 'neurogenic': [18], 'differentiation,': [19], 'has': [20], 'now': [21], 'been': [22], 'identified': [23, 94], 'as': [24, 85], 'a': [25, 37, 86], 'differentiation': [26, 54, 69, 138], 'factor': [27], 'neurogenesis': [29, 110], 'because': [30], '(i)': [31], 'it': [32], 'is': [33, 117], 'expressed': [34], 'transiently': [35], 'subset': [38], 'of': [39, 51, 62, 70, 119, 122], 'neurons': [40, 57, 81], 'the': [42, 49, 103, 123, 136], 'central': [43], 'and': [44, 58, 82, 113, 116], 'peripheral': [45], 'nervous': [46], 'systems': [47], 'at': [48], 'time': [50], 'their': [52], 'terminal': [53, 137], 'into': [55, 80, 126], 'mature': [56], '(ii)': [59], 'ectopic': [60], 'expression': [61], 'neuroD': [63, 74, 98, 132], 'Xenopus': [65], 'embryos': [66], 'causes': [67], 'premature': [68], 'neuronal': [71, 87, 142], 'precursors.': [72], 'Furthermore,': [73], 'can': [75], 'convert': [76], 'presumptive': [77], 'epidermal': [78], 'cells': [79], 'also': [83], 'act': [84], 'determination': [88], 'gene.': [89], 'However,': [90], 'unlike': [91], 'another': [92], 'previously': [93], 'proneural': [95], 'gene': [96], '(XASH-3),': [97], 'seems': [99], 'competent': [100], 'to': [101], 'bypass': [102], 'normal': [104], 'inhibitory': [105], 'influences': [106], 'that': [107, 131], 'usually': [108], 'prevent': [109], 'ventral': [112], 'lateral': [114], 'ectoderm': [115, 125], 'capable': [118], 'converting': [120], 'most': [121], 'embryonic': [124], 'neurons.': [127], 'The': [128], 'data': [129], 'suggest': [130], 'may': [133], 'participate': [134], 'step': [139], 'vertebrate': [141]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1972676659', 'counts_by_year': [{'year': 2024, 'cited_by_count': 8}, {'year': 2023, 'cited_by_count': 14}, {'year': 2022, 'cited_by_count': 11}, {'year': 2021, 'cited_by_count': 17}, {'year': 2020, 'cited_by_count': 16}, {'year': 2019, 'cited_by_count': 12}, {'year': 2018, 'cited_by_count': 14}, {'year': 2017, 'cited_by_count': 13}, {'year': 2016, 'cited_by_count': 14}, {'year': 2015, 'cited_by_count': 21}, {'year': 2014, 'cited_by_count': 24}, {'year': 2013, 'cited_by_count': 31}, {'year': 2012, 'cited_by_count': 26}], 'updated_date': '2024-12-16T03:15:35.024145', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
