Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1972038509', 'doi': 'https://doi.org/10.1016/s0022-5347(01)69134-1', 'title': 'USE OF GREEN FLUORESCENT PROTEIN TO MEASURE TUMOR GROWTH IN AN IMPLANTED BLADDER TUMOR MODEL', 'display_name': 'USE OF GREEN FLUORESCENT PROTEIN TO MEASURE TUMOR GROWTH IN AN IMPLANTED BLADDER TUMOR MODEL', 'publication_year': 2002, 'publication_date': '2002-02-01', 'ids': {'openalex': 'https://openalex.org/W1972038509', 'doi': 'https://doi.org/10.1016/s0022-5347(01)69134-1', 'mag': '1972038509', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11792961'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0022-5347(01)69134-1', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5082037761', 'display_name': 'Suzy V. Torti', 'orcid': 'https://orcid.org/0000-0001-9236-1863'}, 'institutions': [{'id': 'https://openalex.org/I47251452', 'display_name': 'Wake Forest University', 'ror': 'https://ror.org/0207ad724', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I47251452']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'SUZY V. TORTI', 'raw_affiliation_strings': ['From the Departments of Biochemistry, Cancer Biology, Pathology and Medicine and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina'], 'affiliations': [{'raw_affiliation_string': 'From the Departments of Biochemistry, Cancer Biology, Pathology and Medicine and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina', 'institution_ids': ['https://openalex.org/I47251452']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050357987', 'display_name': 'MEG GOLDEN-FLEET', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I47251452', 'display_name': 'Wake Forest University', 'ror': 'https://ror.org/0207ad724', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I47251452']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'MEG GOLDEN-FLEET', 'raw_affiliation_strings': ['From the Departments of Biochemistry, Cancer Biology, Pathology and Medicine and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina'], 'affiliations': [{'raw_affiliation_string': 'From the Departments of Biochemistry, Cancer Biology, Pathology and Medicine and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina', 'institution_ids': ['https://openalex.org/I47251452']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085840629', 'display_name': 'Mark C. Willingham', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I47251452', 'display_name': 'Wake Forest University', 'ror': 'https://ror.org/0207ad724', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I47251452']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'MARK C. WILLINGHAM', 'raw_affiliation_strings': ['From the Departments of Biochemistry, Cancer Biology, Pathology and Medicine and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina'], 'affiliations': [{'raw_affiliation_string': 'From the Departments of Biochemistry, Cancer Biology, Pathology and Medicine and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina', 'institution_ids': ['https://openalex.org/I47251452']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074953539', 'display_name': 'Rong Ma', 'orcid': 'https://orcid.org/0000-0002-5896-9178'}, 'institutions': [{'id': 'https://openalex.org/I47251452', 'display_name': 'Wake Forest University', 'ror': 'https://ror.org/0207ad724', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I47251452']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'RONG MA', 'raw_affiliation_strings': ['From the Departments of Biochemistry, Cancer Biology, Pathology and Medicine and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina'], 'affiliations': [{'raw_affiliation_string': 'From the Departments of Biochemistry, Cancer Biology, Pathology and Medicine and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina', 'institution_ids': ['https://openalex.org/I47251452']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075533504', 'display_name': 'MJ Cline', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I47251452', 'display_name': 'Wake Forest University', 'ror': 'https://ror.org/0207ad724', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I47251452']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'MARK CLINE', 'raw_affiliation_strings': ['From the Departments of Biochemistry, Cancer Biology, Pathology and Medicine and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina'], 'affiliations': [{'raw_affiliation_string': 'From the Departments of Biochemistry, Cancer Biology, Pathology and Medicine and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina', 'institution_ids': ['https://openalex.org/I47251452']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5009285644', 'display_name': 'YOSHIRO SAKIMOTO', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I47251452', 'display_name': 'Wake Forest University', 'ror': 'https://ror.org/0207ad724', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I47251452']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'YOSHIRO SAKIMOTO', 'raw_affiliation_strings': ['From the Departments of Biochemistry, Cancer Biology, Pathology and Medicine and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina'], 'affiliations': [{'raw_affiliation_string': 'From the Departments of Biochemistry, Cancer Biology, Pathology and Medicine and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina', 'institution_ids': ['https://openalex.org/I47251452']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5087773842', 'display_name': 'Frank M. Torti', 'orcid': 'https://orcid.org/0000-0003-3640-6902'}, 'institutions': [{'id': 'https://openalex.org/I47251452', 'display_name': 'Wake Forest University', 'ror': 'https://ror.org/0207ad724', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I47251452']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'FRANK M. TORTI', 'raw_affiliation_strings': ['From the Departments of Biochemistry, Cancer Biology, Pathology and Medicine and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina'], 'affiliations': [{'raw_affiliation_string': 'From the Departments of Biochemistry, Cancer Biology, Pathology and Medicine and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina', 'institution_ids': ['https://openalex.org/I47251452']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.648, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 10, 'citation_normalized_percentile': {'value': 0.631886, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 80, 'max': 81}, 'biblio': {'volume': '167', 'issue': '2 Part 1', 'first_page': '724', 'last_page': '728'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12996', 'display_name': 'Engineering Bacteria for Cancer Treatment', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1305', 'display_name': 'Biotechnology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12996', 'display_name': 'Engineering Bacteria for Cancer Treatment', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1305', 'display_name': 'Biotechnology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10458', 'display_name': 'Diagnosis and Treatment of Bladder Cancer', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10631', 'display_name': 'Metabolic Reprogramming in Cancer Biology', 'score': 0.9869, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/fluorescent-protein-imaging', 'display_name': 'Fluorescent Protein Imaging', 'score': 0.608784}, {'id': 'https://openalex.org/keywords/tumor-microenvironment', 'display_name': 'Tumor Microenvironment', 'score': 0.589546}, {'id': 'https://openalex.org/keywords/tumor-regression', 'display_name': 'Tumor Regression', 'score': 0.575811}, {'id': 'https://openalex.org/keywords/tumor-targeting', 'display_name': 'Tumor Targeting', 'score': 0.568915}, {'id': 'https://openalex.org/keywords/bladder-cancer', 'display_name': 'Bladder Cancer', 'score': 0.501743}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7736462}, {'id': 'https://openalex.org/C2780352672', 'wikidata': 'https://www.wikidata.org/wiki/Q504775', 'display_name': 'Bladder cancer', 'level': 3, 'score': 0.6330213}, {'id': 'https://openalex.org/C2779399171', 'wikidata': 'https://www.wikidata.org/wiki/Q1483951', 'display_name': 'Malignancy', 'level': 2, 'score': 0.53450125}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.4648271}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.44088015}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.37188685}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.24202293}], 'mesh': [{'descriptor_ui': 'D002295', 'descriptor_name': 'Carcinoma, Transitional Cell', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D008164', 'descriptor_name': 'Luminescent Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D001749', 'descriptor_name': 'Urinary Bladder Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002295', 'descriptor_name': 'Carcinoma, Transitional Cell', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004797', 'descriptor_name': 'Enzyme-Linked Immunosorbent Assay', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005455', 'descriptor_name': 'Fluorescent Antibody Technique', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049452', 'descriptor_name': 'Green Fluorescent Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007202', 'descriptor_name': 'Indicators and Reagents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008809', 'descriptor_name': 'Mice, Inbred C3H', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001749', 'descriptor_name': 'Urinary Bladder Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0022-5347(01)69134-1', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11792961', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 24, 'referenced_works': ['https://openalex.org/W100080955', 'https://openalex.org/W127850330', 'https://openalex.org/W1839724716', 'https://openalex.org/W1892170525', 'https://openalex.org/W1978372269', 'https://openalex.org/W1979237379', 'https://openalex.org/W1985226366', 'https://openalex.org/W2006685379', 'https://openalex.org/W2036346134', 'https://openalex.org/W2036742051', 'https://openalex.org/W2038756774', 'https://openalex.org/W2089471699', 'https://openalex.org/W2097282168', 'https://openalex.org/W2108447763', 'https://openalex.org/W2113731644', 'https://openalex.org/W2123927174', 'https://openalex.org/W2147203697', 'https://openalex.org/W2147244050', 'https://openalex.org/W2168430786', 'https://openalex.org/W2408952928', 'https://openalex.org/W2409590448', 'https://openalex.org/W2436886341', 'https://openalex.org/W2886164689', 'https://openalex.org/W3142378523'], 'related_works': ['https://openalex.org/W4389671191', 'https://openalex.org/W4312779314', 'https://openalex.org/W4247453431', 'https://openalex.org/W3153228984', 'https://openalex.org/W2898558914', 'https://openalex.org/W2793887421', 'https://openalex.org/W2377100155', 'https://openalex.org/W2092561569', 'https://openalex.org/W2032491827', 'https://openalex.org/W1965152511'], 'abstract_inverted_index': {'No': [0], 'AccessJournal': [1], 'of': [2, 174, 181, 197, 205, 219, 236, 242, 268, 296, 316, 352, 377, 381, 396, 417, 421, 446, 466, 472, 493, 516, 539, 546, 562, 580, 602, 681, 707, 745, 764, 772, 789, 831, 848, 863, 891, 951, 988, 1032, 1062, 1075, 1102, 1117, 1149, 1164, 1197], 'UrologyINVESTIGATIVE': [3], 'UROLOGY1': [4], 'Feb': [5], '2002USE': [6], 'OF': [7, 1018], 'GREEN': [8], 'FLUORESCENT': [9], 'PROTEIN': [10], 'TO': [11, 1022], 'MEASURE': [12, 1023], 'TUMOR': [13, 19, 1025], 'GROWTH': [14, 1026], 'IN': [15, 1027], 'AN': [16], 'IMPLANTED': [17], 'BLADDER': [18, 1024], 'MODEL': [20], 'SUZY': [21, 39, 1246], 'V.': [22, 40, 42, 1247], 'TORTI,': [23], 'MEG': [24, 50, 1254], 'GOLDEN-FLEET,': [25], 'MARK': [26, 31, 59, 79, 1261, 1276], 'C.': [27, 60, 62, 1262], 'WILLINGHAM,': [28], 'RONG': [29, 70, 1269], 'MA,': [30], 'CLINE,': [32], 'YOSHIRO': [33, 88, 1283], 'SAKIMOTO,': [34], 'and': [35, 97, 132, 167, 212, 225, 258, 291, 332, 432, 666, 686, 742, 775, 794, 853, 855, 889, 936, 958, 982, 1013, 1056, 1096, 1143, 1190, 1201], 'FRANK': [36, 98, 1290], 'M.': [37, 99, 101, 1291], 'TORTI': [38, 43, 102, 1248, 1292], 'TORTISUZY': [41], 'More': [44, 53, 64, 73, 82, 91, 103, 1249, 1256, 1264, 1271, 1278, 1285, 1293], 'articles': [45, 54, 65, 74, 83, 92, 104, 1250, 1257, 1265, 1272, 1279, 1286, 1294], 'by': [46, 55, 66, 75, 84, 93, 105, 292, 427, 567, 723, 869, 874, 1203, 1235, 1251, 1258, 1266, 1273, 1280, 1287, 1295], 'this': [47, 56, 67, 76, 85, 94, 106, 150, 223, 280, 317, 353, 1252, 1259, 1267, 1274, 1281, 1288, 1296], 'author': [48, 57, 68, 77, 86, 95, 107, 1253, 1260, 1268, 1275, 1282, 1289, 1297], ',': [49, 58, 69, 78, 87, 96], 'GOLDEN-FLEETMEG': [51], 'GOLDEN-FLEET': [52, 1255], 'WILLINGHAMMARK': [61], 'WILLINGHAM': [63, 1263], 'MARONG': [71], 'MA': [72, 1270], 'CLINEMARK': [80], 'CLINE': [81, 1277], 'SAKIMOTOYOSHIRO': [89], 'SAKIMOTO': [90, 1284], 'TORTIFRANK': [100], 'View': [108], 'All': [109, 1299], 'Author': [110], 'Informationhttps://doi.org/10.1016/S0022-5347(01)69134-1AboutFull': [111], 'TextPDF': [112], 'ToolsAdd': [113], 'to': [114, 136, 193, 327, 339, 345, 541, 582, 597, 663], 'favoritesDownload': [115], 'CitationsTrack': [116], 'CitationsPermissionsReprints': [117], 'ShareFacebookLinked': [118], 'InTwitterEmail': [119], 'Abstract': [120], 'Purpose:': [121], 'Bladder': [122, 1063], 'cancer': [123, 176, 247, 642, 661, 994], 'is': [124], 'a': [125, 146, 251, 452, 618, 815, 989, 1108, 1155], 'common': [126], 'malignancy': [127], 'in': [128, 149, 164, 185, 222, 272, 306, 425, 477, 543, 624, 765, 797, 886, 1065, 1107, 1154, 1207], 'which': [129], 'local': [130], 'recurrence': [131], 'distant': [133], 'failure': [134], 'contribute': [135], 'poor': [137], 'patient': [138], 'outcome.': [139], 'The': [140], 'search': [141], 'for': [142, 620], 'improved': [143], 'therapies': [144, 155, 198], 'remains': [145], 'high': [147], 'priority': [148], 'disease.': [151], 'For': [152], 'most': [153], 'experimental': [154], 'animal': [156, 172, 454], 'tumor': [157, 183, 206, 220, 227, 237, 282, 324, 343, 355, 520, 598, 954], 'models': [158, 656], 'represent': [159], 'an': [160, 260, 1066, 1103, 1150], 'important': [161], 'step': [162], 'between': [163], 'vitro': [165, 491, 766], 'testing': [166], 'clinical': [168], 'trials.': [169], 'A': [170, 701, 940, 1028, 1095, 1142, 1189], 'useful': [171], 'model': [173, 189, 224, 706, 944], 'bladder': [175, 182, 231, 246, 403, 424, 450, 475, 500, 519, 548, 564, 641, 953, 993], 'involves': [177], 'the': [178, 191, 195, 216, 243, 266, 275, 311, 336, 350, 382, 422, 514, 790, 846, 952, 1114, 1161], 'orthotopic': [179, 354, 544, 639, 703, 942, 991], 'implantation': [180, 290, 521], 'cells': [184, 228, 241, 273, 662, 1200], 'sygeneic': [186], 'animals.': [187], 'This': [188], 'offers': [190], 'opportunity': [192], 'test': [194], 'efficacy': [196], 'administered': [199], 'systemically': [200], 'or': [201], 'intravesically.': [202], 'However,': [203], 'quantitation': [204], 'growth': [207, 238, 283, 326, 344, 561], 'has': [208], 'been': [209], 'difficult.': [210], 'Materials': [211], 'Methods:': [213], 'To': [214], 'allow': [215], 'quantitative': [217, 798], 'assessment': [218], 'mass': [221], 'differentiate': [226], 'from': [229], 'normal': [230], 'epithelium': [232, 476], 'at': [233, 274], 'early': [234], 'stages': [235], 'we': [239], 'transfected': [240], 'MBT2': [244, 318], 'murine': [245, 402, 563, 640, 992], 'cell': [248, 325, 379, 419, 599, 949, 1195], 'line': [249], 'with': [250, 310, 330, 524, 657], 'vector': [252], 'encoding': [253], 'enhanced': [254], 'green': [255, 269, 297, 319, 614, 658, 682, 746, 768, 791], 'fluorescent': [256, 270, 298, 320, 615, 659, 683, 702, 747, 769, 792, 812], 'protein': [257, 271, 299, 321, 616, 777, 793, 813], 'devised': [259], 'enzyme-linked': [261, 312], 'immunosorbent': [262, 313], 'assay': [263, 281, 314], 'that': [264], 'enables': [265], 'detection': [267], 'pg.': [276], 'level.': [277], 'Results:': [278], 'Using': [279, 1113, 1160], 'can': [284], 'be': [285, 328], 'detected': [286], '7': [287, 488], 'days': [288, 294], 'after': [289], '14': [293, 635], 'levels': [295], 'are': [300], 'more': [301], 'than': [302, 305], '500-fold': [303], 'greater': [304], 'controls.': [307], 'Conclusions:': [308], 'Combined': [309], 'use': [315], 'transfectant': [322], 'allows': [323], 'monitored': [329], 'sensitivity': [331], 'reproducibility.': [333], 'It': [334], 'reduces': [335], 'time': [337], 'required': [338], 'measure': [340], 'effects': [341], 'on': [342, 401, 449, 469, 880], '2': [346, 373, 1225], 'weeks,': [347], 'while': [348], 'preserving': [349], 'advantages': [351], 'model.': [356, 455], 'References': [357], '1': [358], ':': [359, 374, 394, 409, 415, 444, 464, 489, 510, 535, 559, 578, 594, 612, 636, 652, 677, 700, 719, 739, 761, 787, 810, 829], 'Cancer': [360, 364, 406, 481, 527, 551, 644, 668, 711, 850, 857, 1064], 'statistics,': [361], '2000.': [362], 'CA': [363], 'J': [365, 479, 502, 570], 'Clin2000;': [366], '50:': [367], '7.': [368], 'Crossref,': [369, 389, 439, 589, 607, 631, 673, 695, 734, 756, 782, 805, 824, 841], 'Medline,': [370, 390, 411, 440, 460, 485, 531, 555, 590, 608, 632, 648, 696, 715, 735, 757, 783, 806, 825, 842], 'Google': [371, 391, 412, 441, 461, 486, 507, 532, 556, 575, 591, 609, 633, 649, 674, 697, 716, 736, 758, 784, 807, 826, 843], 'Scholar': [372, 392, 413, 442, 462, 487, 508, 533, 557, 576, 592, 610, 634, 650, 675, 698, 717, 737, 759, 785, 808, 827, 844], 'Systemic': [375], 'chemotherapy': [376, 398, 542], 'transitional': [378, 418], 'carcinoma': [380, 420, 950], 'urothelium.': [383], 'Semin': [384], 'Surg': [385, 456], 'Oncol1997;': [386], '13:': [387], '365.': [388], '3': [393], 'Effectiveness': [395], 'long-term': [397], 'and/or': [399], 'BCG': [400], 'cancer.': [404, 549, 710], 'Natl': [405, 480, 689, 728, 750], 'Inst': [407], 'Monogr1978;': [408], '327.': [410], '4': [414], 'Induction': [416], 'urinary': [423], 'rats': [426], 'feeding': [428], 'N-[4-(5-nitro-2-furyl)-2-thiazolyl]': [429, 495], 'formamide.': [430], 'Histological': [431], 'ultrastructural': [433], 'findings.': [434], 'Urol': [435], 'Res1978;': [436], '6:': [437], '19.': [438], '5': [443], 'Effect': [445, 1101, 1148], 'chemotherapeutic': [447], 'agents': [448], 'cancer:': [451], 'new': [453], 'Forum1973;': [457], '24:': [458], '542.': [459], '6': [463, 1037], 'Effects': [465], 'donor': [467], 'age': [468], 'neoplastic': [470, 583], 'transformation': [471], 'adult': [473], 'mouse': [474, 499, 518, 655], 'vitro.': [478], 'Inst1979;': [482], '62:': [483], '1017.': [484], 'In': [490], 'characterization': [492, 987], 'four': [494], 'formamide': [496], '(FANFT)': [497], 'induced': [498], 'tumors.': [501], 'Urol1982;': [503], '127:': [504], '1233.': [505], 'Link,': [506, 574], '8': [509], 'Technical': [511], 'factors': [512], 'affecting': [513], 'reproducibility': [515], 'intravesical': [517], 'during': [522], 'therapy': [523], 'bacillus': [525], 'Calmette-Guerin.': [526], 'Res1984;': [528], '44:': [529], '3051.': [530], '9': [534], 'Magnetic': [536], 'resonance': [537], 'imaging': [538, 680, 888], 'response': [540], 'xenografts': [545], 'human': [547, 708, 946, 1198], 'Clin': [550], 'Res1997;': [552], '3:': [553], '1635.': [554], '10': [558], 'Intravesical': [560], 'tumors': [565, 685], 'assessed': [566], 'transrectal': [568], 'ultrasound.': [569], 'Urol1993;': [571], '150:': [572], '525.': [573], '11': [577], 'Susceptibility': [579], 'urothelium': [581], 'cellular': [584], 'implantation.': [585], 'Urology1975;': [586], '5:': [587, 629], '824.': [588], '12': [593], 'Urothelial': [595], 'susceptibility': [596], 'implantation:': [600], 'influence': [601], 'cauterization.': [603], 'Cancer1980;': [604], '46:': [605], '1158.': [606], '13': [611], 'Chimeric': [613], 'as': [617, 814], 'tool': [619], 'visualizing': [621], 'subcellular': [622], 'organelles': [623], 'living': [625], 'cells.': [626], 'Curr': [627], 'Biol1995;': [628], '635.': [630], 'Optimizing': [637], 'syngeneic': [638, 990], '(MB49).': [643], 'Res1999;': [645, 712], '59:': [646, 713], '2834.': [647], '15': [651], 'Orthotopic': [653, 1067], 'transplant': [654], 'protein-expressing': [660, 684], 'visualize': [664], 'metastasis': [665, 705], 'angiogenesis.': [667], 'Metastasis': [669], 'Rev1999;': [670], '17:': [671], '271.': [672], '16': [676], 'Whole-body': [678], 'optical': [679], 'metastases.': [687], 'Proc': [688, 727, 749], 'Acad': [690, 729, 751], 'Sci': [691, 730, 752], 'USA2000;': [692, 731], '97:': [693, 732], '1206.': [694], '17': [699], 'bone': [704], 'prostate': [709], '781.': [714], '18': [718], 'Visualizing': [720], 'gene': [721], 'expression': [722], 'whole-body': [724], 'fluorescence': [725, 773, 799, 883], 'imaging.': [726], '12278.': [733], '19': [738], 'Wavelength': [740], 'mutations': [741], 'posttranslational': [743], 'autoxidation': [744], 'protein.': [748, 834], 'USA1994;': [753], '91:': [754], '12501.': [755], '20': [760], 'Reliable': [762], 'quantification': [763], 'synthesized': [767], 'protein:': [770], 'comparison': [771], 'activity': [774], 'total': [776], 'levels.': [778], 'Electrophoresis2001;': [779], '22:': [780], '966.': [781], '21': [786], 'Use': [788], 'its': [795], 'mutants': [796], 'microscopy.': [800], 'Biophys': [801, 820, 836], 'J1997;': [802], '73:': [803], '2782.': [804], '22': [809], 'Green': [811, 1071, 1118, 1165], 'noninvasive': [816], 'intracellular': [817], 'pH': [818], 'indicator.': [819], 'J1998;': [821], '74:': [822], '1591.': [823], '23': [828], 'Renaturation': [830], 'Aequorea': [832], 'green-fluorescent': [833], 'Biochem': [835], 'Res': [837], 'Comm1981;': [838], '101:': [839], '1372.': [840], 'From': [845], 'Departments': [847], 'Biochemistry,': [849], 'Biology,': [851], 'Pathology': [852], 'Medicine': [854], 'Comprehensive': [856], 'Center,': [858], 'Wake': [859], 'Forest': [860], 'University': [861], 'School': [862], 'Medicine,': [864], 'Winston-Salem,': [865], 'North': [866], 'Carolina©': [867], '2002': [868, 1234], 'American': [870, 1236], 'Urological': [871, 1237], 'Association,': [872, 1238], 'Inc.FiguresReferencesRelatedDetailsCited': [873], 'Al‐Gubory': [875], 'K': [876], '(2019)': [877], 'Shedding': [878], 'light': [879], 'fibered': [881], 'confocal': [882], 'microscopy:': [884], 'Applications': [885], 'biomedical': [887], 'therapiesJournal': [890], 'Biophotonics,': [892], '10.1002/jbio.201900146,': [893], 'VOL.': [894, 961, 1000, 1034, 1077, 1124, 1171, 1214], '12,': [895], 'NO.': [896, 963, 1002, 1036, 1079, 1126, 1173, 1216], '11,': [897], 'Online': [898, 966, 1005, 1041, 1082, 1129, 1176, 1219], 'publication': [899, 967, 1006, 1042, 1083, 1130, 1177, 1220], 'date:': [900, 968, 1007, 1043, 1084, 1131, 1178, 1221], '1-Nov-2019.': [901], 'Gills': [902], 'J,': [903, 909, 925, 1047, 1049, 1053], 'Moret': [904], 'R,': [905, 975], 'Zhang': [906], 'X,': [907], 'Nelson': [908], 'Maresh': [910], 'G,': [911], 'Hellmers': [912], 'L,': [913], 'Canter': [914], 'D,': [915, 971, 1087, 1134, 1181], 'Hudson': [916], 'M,': [917, 921, 923, 927, 931, 1045, 1091, 1138, 1185], 'Halat': [918], 'S,': [919, 933], 'Matrana': [920], 'Marino': [922], 'Reiser': [924], 'Shuh': [926], 'Laborde': [928], 'E,': [929, 979], 'Latsis': [930], 'Talwar': [932], 'Bardot': [934], 'S': [935], 'Li': [937], 'L': [938], '(2018)': [939, 1016, 1059], 'patient-derived': [941], 'xenograft': [943], 'enabling': [945], 'high-grade': [947], 'urothelial': [948], 'implantation,': [955], 'growth,': [956], 'angiogenesis,': [957], 'metastasisOncotarget,': [959], '10.18632/oncotarget.26024,': [960], '9,': [962], '66,': [964], '(32718-32729),': [965], '24-Aug-2018.': [969], 'Chade': [970], 'Andrade': [972, 978], 'P,': [973], 'Borra': [974], 'Leite': [976], 'K,': [977, 1089, 1136, 1183], 'Villanova': [980], 'F': [981], 'Srougi': [983], 'M': [984, 1015], '(2008)': [985], 'Histopathological': [986], 'modelInternational': [995], 'braz': [996], 'j': [997], 'urol,': [998], '10.1590/S1677-55382008000200013,': [999], '34,': [1001], '2,': [1003, 1217], '(220-229),': [1004], '1-Mar-2008.': [1008], 'LUO': [1009], 'Y,': [1010], 'CHEN': [1011], 'X': [1012], "O'DONNELL": [1014], 'USE': [1017], 'PROSTATE': [1019], 'SPECIFIC': [1020], 'ANTIGEN': [1021], 'MOUSE': [1029], 'ORTHOTOPIC': [1030], 'MODELJournal': [1031], 'Urology,': [1033, 1076], '172,': [1035], 'Part': [1038, 1226], '1,': [1039, 1127, 1174], '(2414-2420),': [1040], '1-Dec-2004.TANAKA': [1044], 'GEE': [1046], 'CERDA': [1048], 'ROSSER': [1050], 'C,': [1051], 'ZHOU': [1052], 'BENEDICT': [1054], 'W': [1055], 'GROSSMAN': [1057], 'H': [1058], 'Noninvasive': [1060], 'Detection': [1061], 'Murine': [1068, 1109, 1156], 'Model': [1069, 1112, 1159], 'With': [1070], 'Fluorescence': [1072], 'Protein': [1073], 'CytologyJournal': [1074], '170,': [1078], '3,': [1080], '(975-978),': [1081], '1-Sep-2003.': [1085], 'Yoshida': [1086, 1133, 1180], 'Watanabe': [1088, 1135, 1182], 'Noha': [1090, 1137, 1184], 'Takahashi': [1092, 1139, 1186], 'H,': [1093, 1140, 1187], 'Teramoto': [1094, 1141, 1188], 'Sugisaki': [1097, 1144, 1191], 'Y': [1098, 1145, 1192], '(2003)': [1099, 1146], 'Anti-invasive': [1100, 1147], 'Anti-Matrix': [1104, 1151], 'Metalloproteinase': [1105, 1152], 'Agent': [1106, 1153], 'Brain': [1110, 1157], 'Slice': [1111, 1158], 'Serial': [1115, 1162], 'Monitoring': [1116, 1163], 'Fluorescent': [1119, 1166], 'Protein-labeled': [1120, 1167], 'Glioma': [1121, 1168], 'CellsNeurosurgery,': [1122, 1169], '10.1227/00006123-200301000-00024,': [1123], '52,': [1125, 1172], '(187-197),': [1128, 1175], '1-Jan-2003.': [1132, 1179], '10.1097/00006123-200301000-00024,': [1170], '(2002)': [1193], 'Tracking': [1194], 'invasion': [1196], 'glioma': [1199], 'suppression': [1202], 'anti-matrix': [1204], 'metalloproteinase': [1205], 'agent': [1206], 'rodent': [1208], 'brain-slice': [1209], 'modelBrain': [1210], 'Tumor': [1211], 'Pathology,': [1212], '10.1007/BF02478930,': [1213], '19,': [1215], '(69-76),': [1218], '1-Sep-2002.': [1222], 'Volume': [1223], '167Issue': [1224], '1February': [1227], '2002Page:': [1228], '724-728': [1229], 'Advertisement': [1230, 1300], 'Copyright': [1231], '&': [1232], 'Permissions©': [1233], 'Inc.Keywordsbladder': [1239], 'neoplasmsfluorescent': [1240], 'antibody': [1241], 'techniquemicebladdertumor': [1242], 'markers,': [1243], 'biologicalMetricsAuthor': [1244], 'Information': [1245], 'Expand': [1298], 'PDF': [1301], 'downloadLoading': [1302], '...': [1303]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1972038509', 'counts_by_year': [{'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}], 'updated_date': '2024-08-15T03:49:15.831439', 'created_date': '2016-06-24'}