Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1971706205', 'doi': 'https://doi.org/10.1006/taap.2001.9222', 'title': 'Persistent, Low-Dose 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure: Effect on Aryl Hydrocarbon Receptor Expression in a Dioxin-Resistance Model', 'display_name': 'Persistent, Low-Dose 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure: Effect on Aryl Hydrocarbon Receptor Expression in a Dioxin-Resistance Model', 'publication_year': 2001, 'publication_date': '2001-08-01', 'ids': {'openalex': 'https://openalex.org/W1971706205', 'doi': 'https://doi.org/10.1006/taap.2001.9222', 'mag': '1971706205', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11509025'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1006/taap.2001.9222', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S42307217', 'display_name': 'Toxicology and Applied Pharmacology', 'issn_l': '0041-008X', 'issn': ['0041-008X', '1096-0333'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5006041037', 'display_name': 'Monique-Andrée Franc', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I185261750', 'display_name': 'University of Toronto', 'ror': 'https://ror.org/03dbr7087', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I185261750']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Monique-Andrée Franc', 'raw_affiliation_strings': ['Department of Pharmacology, University of Toronto, Toronto, Ontario, Canada, M5S 1A8'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, University of Toronto, Toronto, Ontario, Canada, M5S 1A8', 'institution_ids': ['https://openalex.org/I185261750']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030829295', 'display_name': 'Raimo Pohjanvirta', 'orcid': 'https://orcid.org/0000-0003-0952-5746'}, 'institutions': [{'id': 'https://openalex.org/I133731052', 'display_name': 'University of Helsinki', 'ror': 'https://ror.org/040af2s02', 'country_code': 'FI', 'type': 'education', 'lineage': ['https://openalex.org/I133731052']}], 'countries': ['FI'], 'is_corresponding': False, 'raw_author_name': 'Raimo Pohjanvirta', 'raw_affiliation_strings': ['Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland', 'National Public Health Institute, Department of Environmental Medicine, Kuopio, Finland', 'National Veterinary and Food Research Institute, Regional Laboratory of Kuopio, Kuopio, Finland'], 'affiliations': [{'raw_affiliation_string': 'Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland', 'institution_ids': ['https://openalex.org/I133731052']}, {'raw_affiliation_string': 'National Veterinary and Food Research Institute, Regional Laboratory of Kuopio, Kuopio, Finland', 'institution_ids': []}, {'raw_affiliation_string': 'National Public Health Institute, Department of Environmental Medicine, Kuopio, Finland', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011985392', 'display_name': 'Jouko Tuomisto', 'orcid': None}, 'institutions': [], 'countries': ['FI'], 'is_corresponding': False, 'raw_author_name': 'Jouko Tuomisto', 'raw_affiliation_strings': ['National Public Health Institute, Department of Environmental Medicine, Kuopio, Finland'], 'affiliations': [{'raw_affiliation_string': 'National Public Health Institute, Department of Environmental Medicine, Kuopio, Finland', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5053755691', 'display_name': 'Allan B. Okey', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I185261750', 'display_name': 'University of Toronto', 'ror': 'https://ror.org/03dbr7087', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I185261750']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Allan B. Okey', 'raw_affiliation_strings': ['Department of Pharmacology, University of Toronto, Toronto, Ontario, Canada, M5S 1A8'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, University of Toronto, Toronto, Ontario, Canada, M5S 1A8', 'institution_ids': ['https://openalex.org/I185261750']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3920, 'currency': 'USD', 'value_usd': 3920, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.922, 'has_fulltext': False, 'cited_by_count': 38, 'citation_normalized_percentile': {'value': 0.740257, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '175', 'issue': '1', 'first_page': '43', 'last_page': '53'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10122', 'display_name': 'Impact of Persistent Organic Pollutants on Environment and Health', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2307', 'display_name': 'Health, Toxicology and Mutagenesis'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10122', 'display_name': 'Impact of Persistent Organic Pollutants on Environment and Health', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2307', 'display_name': 'Health, Toxicology and Mutagenesis'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10433', 'display_name': 'Genotoxicity and Carcinogenesis Mechanisms', 'score': 0.9953, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T14072', 'display_name': 'Immunotoxicology in Toxicologic Pathology Research', 'score': 0.9819, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/aryl-hydrocarbon-receptor', 'display_name': 'Aryl Hydrocarbon Receptor', 'score': 0.573166}, {'id': 'https://openalex.org/keywords/tetrachlorodibenzo-p-dioxin', 'display_name': 'Tetrachlorodibenzo-p-dioxin', 'score': 0.45341477}], 'concepts': [{'id': 'https://openalex.org/C33594762', 'wikidata': 'https://www.wikidata.org/wiki/Q155750', 'display_name': 'Aryl hydrocarbon receptor', 'level': 4, 'score': 0.95735466}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.72378653}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.7138543}, {'id': 'https://openalex.org/C2778938600', 'wikidata': 'https://www.wikidata.org/wiki/Q389934', 'display_name': 'Agonist', 'level': 3, 'score': 0.6491945}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.6469605}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.57889575}, {'id': 'https://openalex.org/C29730261', 'wikidata': 'https://www.wikidata.org/wiki/Q274160', 'display_name': 'Toxicity', 'level': 2, 'score': 0.54602766}, {'id': 'https://openalex.org/C207001950', 'wikidata': 'https://www.wikidata.org/wiki/Q141124', 'display_name': 'In vivo', 'level': 2, 'score': 0.5223823}, {'id': 'https://openalex.org/C2909724048', 'wikidata': 'https://www.wikidata.org/wiki/Q52822', 'display_name': 'Tetrachlorodibenzo-p-dioxin', 'level': 3, 'score': 0.45341477}, {'id': 'https://openalex.org/C24998067', 'wikidata': 'https://www.wikidata.org/wiki/Q4114622', 'display_name': 'Stimulation', 'level': 2, 'score': 0.45245892}, {'id': 'https://openalex.org/C79410662', 'wikidata': 'https://www.wikidata.org/wiki/Q1251001', 'display_name': 'Dose–response relationship', 'level': 2, 'score': 0.41343182}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.21730721}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.12571967}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.119312376}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C150903083', 'wikidata': 'https://www.wikidata.org/wiki/Q7108', 'display_name': 'Biotechnology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000072317', 'descriptor_name': 'Polychlorinated Dibenzodioxins', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D018336', 'descriptor_name': 'Receptors, Aryl Hydrocarbon', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D013723', 'descriptor_name': 'Teratogens', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001835', 'descriptor_name': 'Body Weight', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001835', 'descriptor_name': 'Body Weight', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D004147', 'descriptor_name': 'Dioxins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004147', 'descriptor_name': 'Dioxins', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': False}, {'descriptor_ui': 'D004351', 'descriptor_name': 'Drug Resistance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004351', 'descriptor_name': 'Drug Resistance', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015151', 'descriptor_name': 'Immunoblotting', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D023421', 'descriptor_name': 'Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009929', 'descriptor_name': 'Organ Size', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009929', 'descriptor_name': 'Organ Size', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D000072317', 'descriptor_name': 'Polychlorinated Dibenzodioxins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011869', 'descriptor_name': 'Radioligand Assay', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020318', 'descriptor_name': 'Rats, Long-Evans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017208', 'descriptor_name': 'Rats, Wistar', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018336', 'descriptor_name': 'Receptors, Aryl Hydrocarbon', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018336', 'descriptor_name': 'Receptors, Aryl Hydrocarbon', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D018336', 'descriptor_name': 'Receptors, Aryl Hydrocarbon', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D013723', 'descriptor_name': 'Teratogens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013950', 'descriptor_name': 'Thymus Gland', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D013950', 'descriptor_name': 'Thymus Gland', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D013950', 'descriptor_name': 'Thymus Gland', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1006/taap.2001.9222', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S42307217', 'display_name': 'Toxicology and Applied Pharmacology', 'issn_l': '0041-008X', 'issn': ['0041-008X', '1096-0333'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11509025', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Life on land', 'id': 'https://metadata.un.org/sdg/15', 'score': 0.56}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 67, 'referenced_works': ['https://openalex.org/W1558990295', 'https://openalex.org/W1881962288', 'https://openalex.org/W1954721684', 'https://openalex.org/W1967001791', 'https://openalex.org/W1979889746', 'https://openalex.org/W198065351', 'https://openalex.org/W1982212325', 'https://openalex.org/W1984975838', 'https://openalex.org/W1988801970', 'https://openalex.org/W1990504140', 'https://openalex.org/W1990791950', 'https://openalex.org/W1998106069', 'https://openalex.org/W1998928723', 'https://openalex.org/W1999841869', 'https://openalex.org/W1999869242', 'https://openalex.org/W1999928710', 'https://openalex.org/W2001141951', 'https://openalex.org/W2001977396', 'https://openalex.org/W2011032393', 'https://openalex.org/W2011582760', 'https://openalex.org/W2014588425', 'https://openalex.org/W2017798775', 'https://openalex.org/W2020116570', 'https://openalex.org/W2023877360', 'https://openalex.org/W2027153670', 'https://openalex.org/W2029514547', 'https://openalex.org/W2038347851', 'https://openalex.org/W2038657917', 'https://openalex.org/W2041744572', 'https://openalex.org/W2042352745', 'https://openalex.org/W2045931107', 'https://openalex.org/W2046271197', 'https://openalex.org/W2050572437', 'https://openalex.org/W2055174954', 'https://openalex.org/W2056913333', 'https://openalex.org/W2058887941', 'https://openalex.org/W2059709609', 'https://openalex.org/W2060065906', 'https://openalex.org/W2064230641', 'https://openalex.org/W2068704915', 'https://openalex.org/W2068861533', 'https://openalex.org/W2075860090', 'https://openalex.org/W2077218577', 'https://openalex.org/W2080020022', 'https://openalex.org/W2080482503', 'https://openalex.org/W2082589589', 'https://openalex.org/W2084142664', 'https://openalex.org/W2086828878', 'https://openalex.org/W2093088098', 'https://openalex.org/W2094234986', 'https://openalex.org/W2094806500', 'https://openalex.org/W2114629114', 'https://openalex.org/W2118294936', 'https://openalex.org/W2126732233', 'https://openalex.org/W2128635872', 'https://openalex.org/W2131562982', 'https://openalex.org/W2136306660', 'https://openalex.org/W2152658714', 'https://openalex.org/W2159804776', 'https://openalex.org/W2165627850', 'https://openalex.org/W2167381827', 'https://openalex.org/W2296154126', 'https://openalex.org/W2402361528', 'https://openalex.org/W2414742511', 'https://openalex.org/W2419374242', 'https://openalex.org/W2900468862', 'https://openalex.org/W4293247451'], 'related_works': ['https://openalex.org/W3011241681', 'https://openalex.org/W2915223986', 'https://openalex.org/W2804543904', 'https://openalex.org/W2782163644', 'https://openalex.org/W2463801086', 'https://openalex.org/W2382593370', 'https://openalex.org/W2106828929', 'https://openalex.org/W2063373861', 'https://openalex.org/W1989060705', 'https://openalex.org/W1971905597'], 'abstract_inverted_index': {'Most': [0], 'toxic': [1], 'effects': [2], 'of': [3, 18, 29, 42, 51, 184, 192, 203, 237], '2,3,7,8-tetrachlorodibenzo-p-dioxin': [4], '(TCDD)': [5], 'are': [6], 'mediated': [7], 'by': [8, 119, 129, 205], 'the': [9, 49, 116, 126, 190, 200, 213, 235], 'aryl': [10], 'hydrocarbon': [11], 'receptor': [12, 24, 187, 242], '(AHR).': [13], 'A': [14], 'single,': [15], 'acute': [16, 66, 222], 'dose': [17], 'TCDD': [19, 67, 92, 141, 175, 206, 223, 238], 'can': [20], 'alter': [21], 'its': [22, 240], 'own': [23, 241], 'levels': [25, 112, 188, 230], 'thus': [26], 'complicating': [27], 'evaluation': [28], 'dose–response': [30, 233], 'relationships': [31], 'for': [32, 95], 'AHR-mediated': [33], 'events.': [34], 'Since': [35], 'environmental': [36], 'exposure': [37, 53, 224], 'to': [38, 65, 101, 171, 199, 212, 219, 251], 'dioxins': [39], 'is': [40, 196, 248], 'typically': [41], 'a': [43, 156], 'repeated': [44], 'low-dose': [45], 'nature,': [46], 'we': [47], 'examined': [48], 'effect': [50, 236], 'such': [52], 'on': [54, 239], 'AHR': [55, 111, 132, 147, 166, 180, 204, 216, 229], 'expression.': [56, 181], 'Three': [57], 'rat': [58], 'strains': [59], 'differing': [60], 'greatly': [61, 178], 'in': [62, 109, 142, 189, 197, 208, 215, 225, 228], 'their': [63], 'sensitivity': [64, 170], 'lethality,': [68], 'Long–Evans': [69], '(Turku': [70], 'AB)': [71], '(L-E)': [72], '(LD50': [73, 79, 86], '∼10': [74], 'μg/kg);': [75, 81], 'Sprague': [76], 'Dawley': [77], '(SD)': [78], '∼50': [80], 'and': [82, 105, 122, 124, 144, 168, 211], 'Han/Wistar': [83], '(Kuopio)': [84], '(H/W)': [85], '>': [87], '9600': [88], 'μg/kg),': [89], 'were': [90, 113], 'administered': [91], 'intragastrically,': [93], 'biweekly': [94], '22': [96], 'weeks': [97], 'producing': [98], 'doses': [99], 'equivalent': [100], '0,': [102], '10,': [103], '30,': [104], '100': [106], 'ng/kg/day.': [107], 'Changes': [108, 227], 'hepatic': [110], 'quantitated': [114], 'at': [115, 125, 136, 152, 243], 'protein': [117, 133], 'level': [118, 128], 'radioligand': [120], 'binding': [121], 'immunoblotting': [123], 'mRNA': [127, 148], 'RT–PCR.': [130], 'Cytosolic': [131], 'was': [134, 149, 160], 'elevated': [135, 151], '10': [137], 'or': [138], '30': [139], 'ng/kg/day': [140], 'SD': [143], 'L-E': [145], 'rats;': [146], 'also': [150], 'these': [153], 'doses,': [154], 'suggesting': [155], 'pretranslational': [157], 'mechanism.': [158], 'There': [159], 'no': [161], 'apparent': [162], 'relationship': [163], 'between': [164], 'TCDD-induced': [165], 'regulation': [167], 'strain': [169], 'TCDD.': [172], 'Overall,': [173], '“subchronic”': [174], 'did': [176], 'not': [177], 'perturb': [179], 'The': [182], 'maintenance': [183], 'relatively': [185], 'constant': [186], 'face': [191], 'persistent': [193], 'agonist': [194], 'stimulation': [195], 'contrast': [198], 'sustained': [201], 'depletion': [202], 'observed': [207, 217], 'cell': [209], 'culture': [210], 'fluctuations': [214], 'hours': [218], 'days': [220], 'following': [221], 'vivo.': [226], 'may': [231], 'affect': [232], 'relationships;': [234], 'environmentally': [244], 'relevant': [245], 'dosing': [246], 'schemes': [247], 'therefore': [249], 'important': [250], 'risk': [252], 'assessment.': [253]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1971706205', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-09-09T00:51:49.444402', 'created_date': '2016-06-24'}