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1327, 1333, 1348, 1397, 1605, 1635, 1639, 1649, 1679, 1692, 1700, 1750, 1767, 1914, 1940, 2249, 2266, 2274, 2316, 2346, 2392, 2402, 2408, 2480, 2493, 2504, 2550, 2576, 2591, 2602, 2651, 2681, 2772, 2811, 2827, 2845, 2869, 2880, 2884, 2894, 2904, 2959, 2969, 2992, 3029, 3036, 3043, 3057, 3068, 3084, 3098, 3105, 3116, 3133, 3135, 3149, 3159, 3167, 3184, 3228, 3237, 3241, 3259, 3297, 3352, 3364, 3398, 3485, 3487, 3493, 3504, 3513, 3530, 3533, 3546, 3602, 3622, 3650, 3656, 3717, 3728, 3735, 3763, 3775, 3789, 3799, 3807, 3819, 3831, 3839, 3892, 3900, 3911, 3921, 3926, 3935, 3955, 3959, 3964, 3971, 4047, 4067, 4069, 4146, 4169, 4226, 4273, 4296, 4328, 4354, 4376, 4392, 4412, 4422, 4427, 4439, 4451, 4836, 4865, 4879, 4886, 4893, 4930, 4946, 4967, 4982, 5141, 5165, 5181, 5203, 5241, 5249, 5286, 5294, 5323, 5357], 'active': [38, 276, 1685, 3333, 3370, 3506, 3801, 3832], 'Hsp90-steroid': [39, 277], 'receptor': [40, 278, 477, 1161, 1465, 1652, 2728, 2874, 2886, 2985, 3138, 3245, 3263, 3508, 3769, 3833, 4096, 4126, 4149, 4172, 4198, 4213, 4244, 4259, 4310, 4364, 4388, 5007, 5088, 5315], 'complex.': [41, 279, 3410], 'In': [42, 280, 1004, 2676, 3346, 3902, 4235, 4394, 4434, 4739, 4815, 4952, 4986], 'the': [43, 76, 82, 87, 110, 115, 118, 139, 203, 281, 314, 320, 325, 348, 353, 356, 377, 441, 482, 515, 575, 585, 658, 678, 783, 903, 909, 913, 933, 955, 962, 1007, 1016, 1125, 1137, 1140, 1159, 1277, 1316, 1323, 1346, 1392, 1415, 1462, 1637, 1647, 1650, 1677, 1690, 1705, 1715, 1728, 1748, 1765, 1778, 1835, 1866, 1871, 1931, 1934, 2049, 2055, 2292, 2347, 2352, 2481, 2485, 2491, 2494, 2496, 2663, 2677, 2691, 2727, 2770, 2790, 2794, 2828, 2885, 2888, 2892, 2902, 2960, 2967, 2983, 2990, 3027, 3034, 3041, 3085, 3096, 3103, 3112, 3131, 3136, 3157, 3165, 3182, 3192, 3242, 3302, 3307, 3314, 3350, 3356, 3362, 3408, 3421, 3428, 3446, 3457, 3488, 3491, 3505, 3514, 3528, 3542, 3592, 3664, 3689, 3726, 3742, 3768, 3787, 3800, 3808, 3816, 3820, 3837, 3889, 3933, 3962, 3980, 3988, 4065, 4074, 4080, 4095, 4107, 4114, 4124, 4147, 4170, 4196, 4211, 4222, 4258, 4271, 4283, 4294, 4308, 4326, 4335, 4352, 4362, 4370, 4374, 4387, 4390, 4395, 4420, 4425, 4560, 4740, 4803, 4816, 4862, 4877, 4882, 4891, 4901, 4914, 4917, 4928, 4944, 4955, 4980, 4983, 5005, 5086, 5139, 5142, 5179, 5182, 5187, 5201, 5204, 5214, 5238, 5284, 5295, 5313, 5321, 5329, 5358, 5371, 5379, 5388, 5395], 'present': [44, 132, 282, 370, 1135, 1152, 1460, 2979, 3300, 3354, 3495, 3731, 3894, 4396, 5080, 5171], 'study,': [45, 283, 4397], 'we': [46, 62, 193, 284, 300, 431, 1703, 1722, 1725, 2688, 2738, 2751, 2759, 3025, 3154, 3317, 3348, 3481, 3605, 3723, 3748, 3784, 3907, 4058, 4120, 4240, 4398, 4855, 4869, 5298], 'reinvestigated': [47, 285, 1704], 'activation': [48, 77, 116, 286, 315, 354, 1138, 1253, 1280, 1332, 1396, 2893, 3028, 3056, 5248], 'stripped': [50, 119, 140, 162, 204, 225, 288, 357, 378, 400, 442, 463, 591, 659, 748, 780, 799, 1701, 1729, 1779, 2345, 2391, 2781, 2795, 2873, 2961, 3058, 3086, 3137, 3238, 3243, 3303, 3422, 3956, 3978, 4125, 4148, 4171, 4197, 4212, 4243, 4309, 4363, 4411, 4452, 4703, 4918, 5205, 5296, 5314, 5330, 5359], 'steroid': [51, 289, 938, 1334, 1464, 2537, 2585, 2812, 2852, 2881, 2996, 3008, 3507, 4278], 'isolated': [53, 291, 573, 4402], 'from': [54, 292, 574, 1790, 1798, 1807, 1817, 1826, 1842, 1874, 1879, 1894, 1946, 1982, 2008, 2068, 2135, 2187, 2326, 2599, 2769, 2843, 2855, 2862, 3011, 3019, 3470, 3476, 3968, 3979, 4403, 4787, 4802, 4890], 'either': [55, 91, 293, 329, 2327, 2334, 2773, 2798, 3336, 4404], 'L': [56, 294, 2777, 2863, 3020, 4408], 'cells': [57, 295, 1864, 1901, 2220, 2775, 2778, 2857, 2864, 3013, 3021, 3472, 4406, 4409], 'WCL2': [59, 297, 2304, 2328, 2774, 2856, 3012, 3972, 4405, 5372], 'cells.': [60, 298], 'Surprisingly,': [61, 299, 2837], 'found,': [63, 301], 'using': [64, 302, 1708, 1930, 2333, 2487, 2779, 3107, 3467, 5334], 'highly': [65, 303, 1709, 1733, 3886], 'purified': [66, 304, 1710, 1734, 1945, 1981, 2007, 2050, 2067, 2134, 2186, 2686, 2801, 2870, 2889, 3108, 3140, 3308, 3357, 3458, 4007, 4189, 4780, 5338], 'only': [69, 307, 3032, 3173, 3254, 3373, 3394, 3659, 4039, 4088, 4428, 4840, 5017], 'Hsc70': [72, 165, 197, 221, 310, 403, 435, 459, 1943, 3062, 3309, 3358, 3459, 3515, 3547, 3570, 3657, 3809, 4040, 4051, 4269, 4317, 4368, 4382, 4431, 4447, 5275, 5305, 5352], 'glucocorticoid': [79, 226, 317, 464, 476, 4700], 'presence': [83, 321, 679, 2968, 3113, 3529, 4223, 4272, 4295, 4327, 4353, 4375, 4421, 4883, 5322], 'steroids;': [85, 323], 'absence': [88, 326, 2903, 2991, 3035, 3042, 3115, 3166, 3363, 3963, 4225, 4371, 4391, 4864, 4885], 'p23': [92, 330, 1021, 1217, 1890, 2065, 2095, 2976, 3037, 4217, 4249, 4264, 4289, 4323, 4350], 'molybdate': [94, 332, 1213, 2562], 'also': [96, 334, 1344, 3039, 3178, 3463, 3663, 3709, 3929, 5232], 'as': [98, 155, 157, 185, 336, 393, 395, 423, 518, 1274, 1309, 1421, 1508, 1510, 1600, 1958, 1985, 2012, 2075, 2138, 2190, 2589, 3124, 3586, 3588, 3693, 3695, 4695, 4798, 4823, 5157, 5300], 'previously.': [100, 338], 'Addition': [101, 339], 'Hop': [103, 128, 151, 183, 341, 366, 389, 421, 804, 953, 1118, 1340, 1406, 1457, 1609, 1640, 1738, 1851, 1904, 2184, 2871, 3051, 3078, 3145, 3170, 3249, 3260, 3298, 3353, 3377, 3399, 3413, 3431, 3448, 3454, 3494, 3539, 3596, 3630, 3644, 3661, 4455, 4552, 4777, 4791, 4839, 4866, 4938, 5127, 5192], 'Ydj1': [105, 343, 1275, 1743, 2132, 2423, 3823, 5078, 5129, 5194], 'had': [106, 344, 1643, 3146, 4179], 'no': [107, 345, 604, 1644, 2753, 3713, 4180], 'affect': [108, 346, 2878, 3181, 3932], 'on': [109, 347, 1646, 1953, 2073, 2614, 2679, 3635, 3715, 3741, 4182, 4437, 4742, 5227, 5270, 5292, 5312], 'rate': [111, 349, 3097, 3104, 3132, 3158, 3183, 4878], 'magnitude': [113, 351], 'receptors,': [120, 205, 358, 443, 3447], 'quantitative': [122, 360, 3320, 3743], 'Western': [123, 361, 3321, 3417, 3744], 'blots': [124, 362, 3322, 3745], 'confirmed': [125, 363], 'neither': [127, 365, 3627], 'were': [131, 369, 1841, 1873, 1905, 2096, 2221, 2235, 2277, 2397, 2470, 2498, 2539, 2568, 2612, 2625, 2656, 2672, 3327, 3443, 3617, 3977, 3991, 4059, 4305, 4856, 5130, 5146, 5163, 5170], 'our': [134, 372, 1720, 2756, 2764, 2839, 3046, 3074, 3497, 3522, 3609, 3686, 3733, 3896, 4035, 4824, 4850, 5225, 5271], 'preparations': [136, 374], 'receptors.': [141, 379, 4985], 'Furthermore,': [142, 380, 2891, 3153, 3437], 'truncated': [144, 382, 3577, 3615, 3690], 'recombinant': [145, 383, 1923, 3468, 3474, 3927, 4776, 5389], 'Hsp70': [146, 159, 384, 397, 486, 491, 942, 958, 1403, 1507, 1694, 1735, 1755, 1924, 1979, 3251, 3475, 3568, 3578, 3590, 3616, 3691, 3697, 3840, 4541, 4554, 4795, 4827, 5134, 5154, 5208], 'does': [148, 166, 386, 404, 661, 943, 3179, 3947, 4097, 4199, 4542, 5089], 'not': [149, 167, 387, 405, 662, 944, 1143, 1211, 1459, 1740, 2876, 2973, 3031, 3053, 3080, 3172, 3180, 3525, 3598, 3646, 3658, 3931, 3938, 3948, 4098, 4165, 4200, 4254, 4543, 4785, 4871, 4937, 5090, 5147, 5245], 'was': [154, 392, 950, 1739, 1788, 1797, 1805, 1816, 1825, 1852, 1878, 1891, 1925, 1944, 1980, 2006, 2052, 2066, 2133, 2185, 2296, 2307, 2321, 2344, 2963, 2972, 3090, 3161, 3264, 3299, 3414, 3449, 3453, 3500, 3692, 3765, 3770, 3966, 4250, 4265, 4290, 4311, 4332, 4343, 4359, 4365, 4383, 4549, 4784], 'effective': [156, 394, 3587, 3619, 3694], 'wild-type': [158, 396, 3589, 3613, 3696], 'activating': [161, 399, 1032, 1414], 'receptor.': [163, 401, 3365, 4919, 5184, 5331, 5360], 'Since': [164, 402, 941, 4034, 4540], 'directly': [169, 201, 407, 439, 945, 1514, 1759, 4055, 4545], 'but': [172, 410, 1322, 3038, 3662, 4340, 5000], 'both': [173, 411, 2851, 3006, 3110, 3344, 3442, 4050, 5346], 'proteins': [174, 412, 540, 544, 597, 793, 896, 1306, 1311, 1329, 1770, 2349, 2396, 2409, 2671, 2802, 3109, 3707, 3976, 4072, 4190, 4415, 5216], 'suggested': [181, 419, 892, 907, 4550], 'acts': [184, 422, 1408], 'bridge': [187, 425], 'between': [188, 426], 'Hsp70.': [191, 429, 4951], 'However,': [192, 430, 2750, 3772, 4256, 5027], 'found': [194, 432, 1723, 2752, 3155, 3785, 3908, 4142, 4241, 4442], 'after': [196, 434, 3438], 'they': [206, 444, 603, 665, 2725, 5145, 5162, 5169], 'fully': [208, 446, 4160], 'reactivated': [209, 447, 668, 4132, 4161], 'by': [210, 448, 598, 669, 930, 1035, 1257, 1314, 1336, 1855, 1908, 1927, 1950, 2071, 2098, 2102, 2279, 2309, 2350, 2483, 2581, 2674, 2683, 2695, 2792, 2887, 2908, 3129, 3139, 3186, 3416, 4162, 4948, 5234, 5351], 'respectively.': [214, 452], 'We,': [215, 453, 3100], 'therefore,': [216, 454, 3101, 3942], 'conclude': [217, 455, 1753], 'independently': [223, 461, 1761, 5279], 'alone': [229, 467, 1119, 3063], 'sufficient': [231, 469, 3065, 5326], 'activate': [233, 471, 1123], 'them': [234, 472, 671, 2782], 'steroids.': [237, 475, 1783], '70-kDa': [478], 'heat': [479, 488, 538], 'shock': [480, 489, 539], 'constitutive': [483], 'isoform': [484], '90-kDa': [487], 'organizing': [494], 'polyacrylamide': [496], 'gel': [497], 'electrophoresis': [498], 'rabbit': [499, 673], 'reticulocyte': [500, 674], 'lysate': [501, 675, 2070], 'N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic': [502], 'acid': [503], 'monoclconal': [504], 'IgG': [505, 510, 1833, 1849, 1869], 'antibody': [506, 511], 'against': [507, 1834, 1850, 1870, 2106], 'GR': [508, 749, 781, 918, 1036, 1349, 1420, 1516, 1730, 1872, 2320, 2343, 2390, 2606, 2682, 2895, 3030, 3069, 3304, 3334, 3371, 3623, 3700, 3753, 3802, 3922, 3936, 3960, 4048, 4401, 4453, 4837, 4860, 4904, 4931, 4947, 4956, 5250, 5281, 5339], 'monoclonal': [509, 1832, 1848, 1868, 5381], 'binds': [513, 1154, 2995, 3540, 3660], 'same': [516, 2692], 'epitope': [517], 'BuGR2': [519, 1831, 2337, 2630], 'A': [520, 2834], 'number': [521], 'nuclear': [523], 'hormone': [524, 914, 926, 1033, 1352, 2746, 2897, 3071], 'kinases': [528], 'involved': [529, 1030], 'signal': [531], 'transduction': [532], 'occur': [533, 4078, 4978], 'multi-protein': [535, 579], 'complexes': [536, 580], 'containing': [537, 1885, 1933, 2094, 2251, 2371, 2389, 2446, 2552, 4775], 'several': [542, 1389], 'additional': [543, 1019], '(1.Pratt': [545, 1467, 1517, 3195], 'W.B.': [546, 560, 620, 640, 694, 714, 757, 812, 849, 875, 967, 1044, 1074, 1097, 1170, 1190, 1231, 1288, 1370, 1468, 1482, 1518, 1584, 2706, 2914, 2940, 3196, 3850, 4463, 4497, 4523, 4569, 4603, 4629, 4722, 4754], 'Toft': [547, 1071, 1431, 1469, 1519, 1858, 2029, 2079, 2199, 3197, 3274, 4674, 5041, 5052, 5108, 5377], 'D.O.': [548, 1072, 1470, 1520, 2080, 2200, 3198], 'Endocr.': [549, 1471, 1521, 3199], 'Rev.': [550, 562, 1472, 1522, 3200], '1997;': [551, 565, 853, 879, 971, 1194, 1235, 1473, 1523, 1542, 2034, 2918, 2944, 3201, 4501, 4527, 4607, 4633, 4726], '18:': [552, 1474, 1524, 3202, 3558, 3678, 3877], '306-360Crossref': [553, 1475, 1525, 3203], 'PubMed': [554, 569, 630, 650, 704, 724, 769, 824, 861, 887, 979, 999, 1056, 1086, 1109, 1182, 1202, 1243, 1300, 1382, 1444, 1476, 1496, 1526, 1545, 1561, 1595, 1625, 1974, 2000, 2042, 2090, 2158, 2180, 2212, 2718, 2926, 2952, 3204, 3287, 3560, 3680, 3862, 3879, 4475, 4509, 4535, 4581, 4615, 4641, 4661, 4687, 4734, 4766, 5065, 5121], 'Scopus': [555, 770, 825, 862, 888, 980, 1000, 1057, 1087, 1110, 1183, 1203, 1244, 1301, 1383, 1445, 1477, 1497, 1527, 1546, 1562, 1668, 2001, 2043, 2159, 2213, 2719, 2927, 2953, 3205, 3288, 3561, 3681, 3863, 3880, 4476, 4510, 4536, 4582, 4616, 4642, 4662, 4688, 4735, 4767, 5066, 5122, 5265], '(1537)': [556, 1478, 1528, 3206], 'Google': [557, 570, 631, 651, 705, 725, 772, 827, 864, 890, 982, 1002, 1059, 1089, 1112, 1185, 1205, 1246, 1303, 1385, 1447, 1479, 1499, 1529, 1548, 1564, 1596, 1626, 1670, 1975, 2003, 2045, 2091, 2161, 2181, 2215, 2721, 2929, 2955, 3207, 3290, 3563, 3683, 3865, 3882, 4478, 4512, 4538, 4584, 4618, 4644, 4664, 4690, 4737, 4769, 5068, 5124, 5267], 'Scholar,': [558, 632, 706, 845, 865, 983, 1060, 1186, 1480, 1530, 1549, 1565, 2162, 2930, 3208, 3866, 4479, 4493, 4513, 4585, 4599, 4619, 4645, 4665, 4718], '2.Pratt': [559], 'Annu.': [561], 'Pharmacol.': [563], 'Toxicol.': [564], '37': [566], '(232):': [567], '297Crossref': [568], 'Scholar).': [571, 652, 726, 773, 828, 1003, 1113, 1247, 1304, 1386, 1448, 1500, 1671, 1976, 2004, 2092, 2182, 2216, 3291, 3564, 3684, 4539, 4738, 5268], 'GR1': [572], 'cytosol': [576, 1949, 2011, 2306, 2332, 2771], 'such': [578, 1273], 'glucocorticoid,': [582], 'but,': [583], 'when': [584, 2957, 3767, 4079, 4133, 4203, 4257, 4282, 4307, 4361], 'immunoadsorbed': [588, 747, 2322, 2767, 3967], 'then': [590, 906, 2569, 2657, 2788, 3992, 4229, 4266, 4320, 4693, 5002], 'associated': [596, 2348, 2395, 2608, 3406, 4414, 4970], 'treatment': [599], 'high': [601], 'salt,': [602], 'longer': [605], 'do': [606], 'so': [607], '(3.Hutchison': [608, 682], 'K.A.': [609, 634, 683, 708, 753, 808, 1040, 1062, 1166, 2702, 4459, 4565, 4750], 'Brott': [610, 684], 'B.K.': [611, 685], 'De': [612, 686], 'Leon': [613, 687], 'J.H.': [614, 688], 'Perdew': [615, 689], 'G.H.': [616, 690], 'Jove': [617, 691], 'R.': [618, 692], 'Pratt': [619, 639, 693, 713, 756, 811, 829, 848, 874, 966, 1043, 1073, 1096, 1169, 1189, 1230, 1262, 1287, 1369, 1583, 2696, 2705, 2913, 2939, 3849, 4462, 4496, 4522, 4568, 4602, 4628, 4721, 4744, 4753, 4894], 'J.': [621, 641, 695, 715, 758, 813, 850, 876, 968, 988, 1045, 1075, 1098, 1171, 1191, 1232, 1289, 1371, 1433, 1537, 1585, 1965, 2031, 2081, 2147, 2166, 2171, 2201, 2707, 2915, 2941, 3276, 3549, 3551, 3553, 3669, 3671, 3673, 3851, 3868, 3870, 3872, 4464, 4498, 4524, 4570, 4604, 4630, 4650, 4676, 4723, 4755, 5054, 5110], 'Biol.': [622, 642, 696, 716, 759, 814, 851, 877, 969, 989, 1046, 1076, 1099, 1172, 1192, 1233, 1290, 1372, 1434, 1541, 1586, 1664, 1966, 2032, 2082, 2148, 2172, 2202, 2708, 2916, 2942, 3277, 3556, 3676, 3852, 3875, 4465, 4499, 4525, 4571, 4605, 4631, 4651, 4677, 4724, 4756, 5055, 5111, 5261], 'Chem.': [623, 697, 760, 815, 852, 878, 970, 990, 1047, 1077, 1100, 1173, 1193, 1234, 1291, 1373, 1435, 1587, 1967, 2033, 2083, 2149, 2173, 2203, 2709, 2917, 2943, 3278, 3853, 4466, 4500, 4526, 4572, 4606, 4632, 4652, 4678, 4725, 4757, 5056, 5112], '1992;': [624, 698, 2174], '267:': [625, 699, 2175], '2902-2908Abstract': [626, 700], 'Full': [627, 647, 701, 721, 764, 766, 819, 821, 856, 858, 882, 884, 974, 976, 994, 996, 1051, 1053, 1081, 1083, 1104, 1106, 1177, 1179, 1197, 1199, 1238, 1240, 1295, 1297, 1377, 1379, 1439, 1441, 1491, 1493, 1592, 1971, 2037, 2039, 2087, 2153, 2155, 2177, 2207, 2209, 2713, 2715, 2921, 2923, 2947, 2949, 3282, 3284, 3857, 3859, 4470, 4472, 4504, 4506, 4530, 4532, 4576, 4578, 4610, 4612, 4636, 4638, 4656, 4658, 4682, 4684, 4729, 4731, 4761, 4763, 5060, 5062, 5116, 5118], 'Text': [628, 648, 702, 722, 765, 767, 820, 822, 857, 859, 883, 885, 975, 977, 995, 997, 1052, 1054, 1082, 1084, 1105, 1107, 1178, 1180, 1198, 1200, 1239, 1241, 1296, 1298, 1378, 1380, 1440, 1442, 1492, 1494, 1593, 1972, 2038, 2040, 2088, 2154, 2156, 2178, 2208, 2210, 2714, 2716, 2922, 2924, 2948, 2950, 3283, 3285, 3858, 3860, 4471, 4473, 4505, 4507, 4531, 4533, 4577, 4579, 4611, 4613, 4637, 4639, 4657, 4659, 4683, 4685, 4730, 4732, 4762, 4764, 5061, 5063, 5117, 5119], 'PDF': [629, 649, 703, 723, 768, 823, 860, 886, 978, 998, 1055, 1085, 1108, 1181, 1201, 1242, 1299, 1381, 1443, 1495, 1594, 1973, 2041, 2089, 2157, 2179, 2211, 2717, 2925, 2951, 3286, 3861, 4474, 4508, 4534, 4580, 4614, 4640, 4660, 4686, 4733, 4765, 5064, 5120], '4.Hutchison': [633, 707], 'Dittmar': [635, 709, 1361, 1483], 'K.D.': [636, 710, 751, 806, 847, 867, 965, 1038, 1091, 1164, 1188, 1223, 1282, 1362, 1484, 2700, 2912, 2932, 3844, 4457, 4495, 4515, 4563, 4601, 4621, 4720, 4748], 'Czar': [637, 711], 'M.J.': [638, 712, 1575], 'Chemp.': [643, 717], '1994;': [644, 718, 1558, 2084], '269:': [645, 719, 2085], '5043-5049Abstract': [646, 720], 'Although': [653, 1114, 1248, 3073, 3191], 'addition': [654, 739, 789, 1005, 2868, 3910, 3925, 4426, 4445], 'reactivate': [663, 1727, 1777, 5328], 'them,': [664], 'can': [666, 1214, 1254, 1512, 4087, 4416, 4905, 5001], 'treating': [670], '(RRL)': [676], 'ATP': [681, 4227, 4297, 4423, 5324, 5347], 'Therefore,': [727, 1130, 3045, 3169, 3490, 3565, 3685, 4119, 4195, 4782, 4920, 5185], 'considerable': [728, 4277, 4341], 'effort': [729], 'gone': [731], 'into': [732], 'determining': [733, 4062], 'what': [734], 'factors': [735], 'RRL,': [737, 3130], 'Hsp90,': [741, 801, 948, 1010, 1115, 1258, 1337, 1405, 1607, 1712, 2412, 3141, 3342, 3440, 3781, 4008, 4449, 4547, 4797, 5074, 5156], 'reactivation': [745, 778, 797, 1699, 1706, 2680, 3067, 3083, 3106, 3128, 3134, 3160, 3185, 3236, 3240, 3486, 3498, 3593, 3601, 3621, 3636, 3649, 3716, 3899, 3920, 3934, 3954, 4046, 4076, 4880, 5293], '(5.Dittmar': [750, 805, 1037, 1163, 2699, 4456, 4562, 4747], 'Hutchison': [752, 807, 1039, 1165, 2701, 4458, 4564, 4749], 'Owens-Grillo': [754, 809, 1041, 1065, 1167, 2703, 4460, 4566, 4751], 'J.K.': [755, 810, 1042, 1066, 1168, 2704, 4461, 4567, 4752], '1996;': [761, 816, 1048, 1174, 1622, 1665, 2710, 4467, 4573, 4758, 5262], '271:': [762, 817, 1049, 1175, 2711, 4468, 4574, 4759], '12833-12839Abstract': [763, 818, 1050, 1176, 2712, 4469, 4575, 4760], '(149)': [771, 826, 1058, 1184, 2720, 4477, 4583, 4768], 'Fractionation': [774], 'RRL': [776, 1796, 2403, 2684, 2799, 2816, 2832, 4004, 4163], 'various': [784, 1680, 2406, 4136], 'fractions': [785], 'revealed': [786], 'that,': [787, 2849, 3123, 3702, 3943, 4143, 4443, 4822], 'ATP,': [791, 2453, 4011, 4274, 4377], 'essential': [795], 'GR:': [800], 'Hsp70,': [802, 1011, 1116, 1259, 1313, 1321, 1338, 1456, 1606, 2415, 3230, 5075], 'associates': [831, 1264, 2698, 4746, 4896, 5043], '(6.Hutchison,': [832, 4705], 'K.': [833, 836, 3210, 3213, 4481, 4484, 4587, 4590, 4706, 4709], 'A.,': [834, 3211, 4482, 4588, 4707], 'Dittmar,': [835, 3212, 4483, 4589, 4708], 'D.,': [837, 3214, 4485, 4591, 4710], 'Pratt,': [839, 3216, 4487, 4593, 4712], 'W.': [840, 2016, 3217, 4488, 4594, 4713], 'B.': [841, 1426, 1617, 2018, 2022, 3218, 3269, 4489, 4595, 4669, 4714, 5047, 5103], '(1994)': [842, 3219, 4490, 4596, 4715], '269,': [843, 3220, 4491, 4597, 4716], '27894–27899Google': [844, 3221, 4492, 4598, 4717], '7.Dittmar': [846, 1187, 4494, 4600, 4719], '272:': [854, 880, 972, 1195, 1236, 2035, 2919, 2945, 4502, 4528, 4608, 4634, 4727], '13047-13054Abstract': [855, 973, 1196, 2920, 4503, 4609, 4728], '(155)': [863, 981, 1204, 2928, 4511, 4617, 4736], '8.Dittmar': [866, 2931, 4514, 4620], 'Demady': [868, 1224, 2933, 4516, 4622], 'D.R.': [869, 1225, 2934, 4517, 4623], 'Stancato': [870, 1063, 1226, 2935, 4518, 4624], 'L.F.': [871, 1064, 1227, 2936, 4519, 4625], 'Krishna': [872, 1069, 1228, 2937, 4520, 4626], 'P.': [873, 1070, 1229, 2938, 4521, 4627], '21213-21220Abstract': [881, 1237, 2946, 4529, 4635], '(235)': [889, 1245, 2954, 4537, 4643], 'Scholar)': [891, 1627, 2722, 3222, 4770, 5069], 'these': [894, 1693, 1768, 4070, 5098], 'together': [898], 'complex': [901, 1162, 1466, 1604, 1653, 2986], 'termed': [902], 'foldosome.': [904, 5167], 'They': [905], 'foldosome': [910, 963, 1393, 3193, 4561, 4804], 'interacts': [911], 'binding': [915, 927, 939, 956, 1034, 1317, 1766, 2538, 2586, 2813, 2882, 2898, 4066, 4279, 4701, 5094, 5288, 5319, 5348], 'domain': [916, 935, 3706], 'an': [920, 4085], 'ATP-dependent': [921], 'reaction': [922, 1221], 'activates': [924], 'its': [925, 937, 2998, 3580, 4128, 4183, 4993, 5009, 5031, 5092, 5220], 'activity,': [928, 5032], 'possibly': [929, 1455, 4378], 'partially': [931], 'unfolding': [932], 'hormone-binding': [934], 'exposing': [936], 'site.': [940], 'interact': [946], 'thought': [951], 'mediated': [954], '(7.Dittmar': [964, 2911], '9.Chen': [984, 4646], 'S.': [985, 1366, 1611, 1661, 4647, 5258], 'Smith': [986, 1618, 1912, 4648, 5393], 'D.F.': [987, 1619, 1659, 4649, 5256], '1998;': [991, 1101, 1292, 1436, 1488, 1997, 2204, 3279, 3557, 3677, 3854, 3876, 4653, 4679, 5057, 5113], '273:': [992, 1102, 1293, 1437, 2205, 3280, 3855, 4654, 4680, 5058, 5114], '35194-35200Abstract': [993, 4655], '(281)': [1001, 4663], 'form': [1015], 'foldosome,': [1017], 'two': [1018, 1769, 4071, 4429, 4984], '(Ydj1),': [1024], 'have': [1025, 3631, 3710, 5070], '10.Hutchison': [1061], 'Johnson': [1067], 'J.L.': [1068, 2078], '1995;': [1078, 2150], '270:': [1079, 2151], '18841-18847Abstract': [1080], '(110)': [1088], 'Scholar,11.Dittmar': [1090], 'Banach': [1092, 1283, 3845], 'M.': [1093, 1284, 1569, 3846], 'Galigniana': [1094, 1285, 1363, 3847], 'M.D.': [1095, 1286, 1364, 3848], '7358-7366Abstract': [1103, 1294, 3856], '(140)': [1111, 1302, 3864], 'able': [1121, 4857], 'GR,': [1124, 1702, 1763, 1836, 2632, 3087, 3239, 3736, 4057, 4440, 4989, 5036], 'activated': [1126, 1160, 1463, 2726, 2739, 2999, 3409], 'unstable.': [1129], 'unless': [1131, 1146], 'steroids': [1132, 1145], 'actually': [1134], 'during': [1136, 5022, 5081], 'process,': [1139], 'will': [1142, 5340], 'fourth': [1148], 'protein,': [1149], 'p23,': [1150, 2421, 2993, 3143, 4010, 5385], 'is': [1151, 1341, 1458, 1503, 1628, 1771, 1774, 2587, 2848, 2987, 3052, 3079, 3171, 3536, 3597, 3645, 4103, 4117, 4820, 4922, 5231, 5244, 5325], 'stabilize': [1158], 'Scholar);': [1206], 'reasons': [1208], 'clear,': [1212], 'substitute': [1215], 'this': [1219, 3295, 3465, 3574, 3607, 3721, 3905, 4847, 4910, 4953, 5020, 5318], 'stabilization': [1220], '(8.Dittmar': [1222], 'basal': [1250], 'level': [1251, 1278, 1749, 3296, 3351, 3492, 3727, 3788, 3838], 'achieved': [1256], 'showed': [1265, 3076, 3122, 3611, 4399], 'catalytic': [1267, 3531], 'amounts': [1268, 3227, 3532], 'increase': [1276, 3095], '(11.Dittmar': [1281, 3843], 'often': [1307], 'act': [1308, 3571], 'partner': [1310], 'facilitating': [1315, 1331], 'substrates': [1319], 'mechanism': [1324], 'action': [1326], 'unclear.': [1342], 'BAG-1': [1343], 'modulates': [1345], 'ability': [1347, 1691, 4129, 4184, 4994, 5010], 'concentration-dependent': [1355], 'manner': [1356], '(12.Kanelakis': [1357], 'K.C.': [1358], 'Morishima': [1359], 'Y.': [1360], 'Takayama': [1365], 'Reed': [1367], 'J.C.': [1368], '1999;': [1374], '274:': [1375], '34134-34140Abstract': [1376], '(74)': [1384, 1498], 'There': [1387, 3535], 'difficulties': [1390], 'model': [1394, 3194], 'GR.': [1398, 3489, 3603, 3651, 3718, 3901, 5228], 'First,': [1399], 'contrast': [1401, 1451, 4987, 5034], 'apparently': [1407], 'catalytically': [1409], 'rather': [1410, 1745, 3917, 4778], 'than': [1411, 1746, 3250, 3427, 3502, 3511, 3756, 3797, 3805, 3918, 4372, 4779], 'stoichiometrically': [1412, 4793], 'progesterone': [1416, 3244, 3262, 4958, 5006, 5087, 5143, 5183, 5206], 'perhaps': [1419, 4972], 'well': [1422, 1509], '(25.Kosano': [1423, 3266, 5044, 5100], 'H.': [1424, 3267, 4667, 5045, 5101], 'Stensgard': [1425, 2017, 3268, 4668, 5046, 5102], 'Charlesworth': [1427, 3270, 4670, 5048, 5104], 'C.M.': [1428, 3271, 4671, 5049, 5105], 'McMahan': [1429, 3272, 4672, 5050, 5106], 'N.': [1430, 2024, 3273, 4673, 5051, 5107], 'D.': [1432, 2030, 3275, 4675, 5053, 5109], '32973-32979Abstract': [1438, 3281, 4681, 5059, 5115], '(208)': [1446, 3289, 4689, 5067, 5123], 'Second,': [1449], '14.Pratt': [1481], 'Trends': [1485], 'Endocrinol.': [1486, 1557, 1621], 'Metab.': [1487], '9:': [1489], '244-252Abstract': [1490], 'Third,': [1501], 'there': [1502], 'strong': [1504], 'evidence': [1505, 3537, 3642], '15.Srinivasan': [1531], 'G.': [1532, 1551, 2020, 2028], 'Post': [1533], 'J.F.M.': [1534], 'Thompson': [1535, 1554], 'E.B.': [1536, 1555], 'Steroid': [1538], 'Biochem.': [1539], 'Mol.': [1540, 1556, 1620, 1662, 3554, 3674, 3873, 5259], '60:': [1543], '1-9Crossref': [1544], '(28)': [1547, 2002], '16.Srinivasan': [1550], 'Patel': [1552], 'N.T.': [1553], '8:': [1559], '189-196Crossref': [1560], '(35)': [1563], '27.Sanchez': [1566], 'E.R.': [1567], 'Hirst': [1568], 'Scherrer': [1570], 'L.C.': [1571], 'Tang': [1572], 'H.Y.': [1573], 'Welsh': [1574], 'Harmon': [1576], 'J.M.': [1577], 'Simmons': [1578], 'Jr.,': [1579], 'S.S.': [1580], 'Ringold': [1581], 'G.M.': [1582], '1990;': [1588, 1968], '265': [1589], '(10130):': [1590], '20123Abstract': [1591], 'Scholar),': [1597, 2046, 2956, 3883, 4691, 5125], 'raising': [1598], 'questions': [1599], 'whether': [1602, 2758, 3294, 4123, 4790, 4807, 4935, 5345], '(26.Chen': [1610], 'Prapapanich': [1612], 'V.': [1613], 'Rimerman': [1614], 'R.A.': [1615], 'Honoré': [1616], '10:': [1623], '682-693Crossref': [1624], 'indeed': [1629], 'activation.': [1632, 1751], 'Finally,': [1633], 'elimination': [1634], 'Sti1,': [1636, 5243], 'homolog': [1638, 5240], 'yeast,': [1642], 'effect': [1645, 3634, 3714, 3818, 4181, 5291], 'Hsp70-Hsp90-steroid': [1651], 'vivo': [1655, 5252], '(17.Chang': [1656, 5253], 'H.C.J.': [1657, 5254], 'Nathan': [1658, 5255], 'Lindquist': [1660, 5257], 'Cell.': [1663, 3555, 3675, 3874, 5260], '17:': [1666, 5263], '318-325Crossref': [1667, 5264], '(193)': [1669, 5266], 'Our': [1672, 3002, 3118], 'laboratory': [1673, 2312, 2847, 2910], 'studying': [1676, 1689], 'properties': [1678, 4964], 'Hsp70s': [1681, 5336], 'mutated': [1682], 'their': [1684, 2761, 4413, 4788, 4963, 5287], 'sites.': [1686], 'Preparatory': [1687], 'mutants': [1695], 'participate': [1697], 'process': [1707, 3594], 'Ydj1.': [1718], 'To': [1719, 2604, 3292, 3719], 'surprise,': [1721], 'could': [1726, 4157, 4870], 'just': [1732], 'Hsp90;': [1737, 3253, 5390], 'required,': [1741], 'reduced': [1744], 'increased': [1747, 3919], 'We': [1752, 2766, 2806, 3462, 3940, 4141, 4208, 5361], 'all': [1772], '[6,7-3H]Triamcinolone': [1784], 'acetonide': [1785, 2593], '(42.8': [1786], 'Ci/mmol)': [1787], 'obtained': [1789, 1806, 2808, 2830, 2854, 3010, 3026, 3482, 4306], 'NEN': [1791], 'Life': [1792], 'Science': [1793], 'Products.': [1794], 'Untreated': [1795], 'Green': [1799], 'Hectares': [1800], '(Oregon,': [1801], 'WI).': [1802], 'Protein': [1803], 'A-Sepharose': [1804], 'Amersham': [1808, 1818, 1880], 'Pharmacia': [1809, 1819, 1881], 'Biotech.': [1810, 1820, 1882], 'Anti-mouse': [1811], 'Ig': [1812], 'horseradish': [1813, 2665], 'peroxidase': [1814], 'conjugate': [1815], 'Complete-Mini': [1821, 2267], 'protease': [1822, 2268], 'inhibitor': [1823, 2269], 'mixture': [1824, 2270, 3734], 'Roche': [1827], 'Molecular': [1828], 'Biochemicals.': [1829], 'The': [1830, 2294, 2467, 2584, 2623, 2654, 3652], 'anti-Hsp40,': [1837], 'anti-Hsp70,': [1838], 'anti-Hsp90': [1840], 'Affinity': [1843], 'Bioreagents': [1844], '(Golden,': [1845], 'CO).': [1846], 'DS14F5': [1847, 2643], 'kindly': [1853, 1906], 'provided': [1854, 1907, 2308], 'David': [1856, 1896, 1910, 5376, 5392], 'O.': [1857, 1897], '(Mayo': [1859], 'Clinic,': [1860], 'Rochester,': [1861], 'MN).': [1862], 'Hybridoma': [1863], 'producing': [1865], 'FiGR': [1867, 2335, 2596], 'ATCC.': [1875], 'ECL': [1876], 'reagent': [1877], 'Escherichia': [1883], 'coliBL21/DE3': [1884], 'plasmid': [1886, 5383, 5396], 'pET23': [1887], 'expressing': [1888, 1902, 5384, 5397], 'human': [1889, 1903, 1941], 'gift': [1893], 'Dr.': [1895, 1909, 5363, 5367, 5375, 5391], 'Toft.': [1898], 'E.': [1899, 1964, 1983, 1993, 2136, 2144, 2188, 3477], 'coli': [1900, 1984, 2137, 2189], 'F.': [1911], '(University': [1913], 'Nebraska': [1915], 'Medical': [1916], 'School,': [1917], 'Omaha,': [1918], 'NE).': [1919], 'Plasmid': [1920], 'encoding': [1921], '60-kDa': [1922], 'constructed': [1926], 'site-directed': [1928], 'mutagenesis': [1929], 'oligonucleotide': [1932], 'stop': [1935], 'codon': [1936], 'position': [1938], '607': [1939], 'hsp70.': [1942], 'bovine': [1947, 2009, 2232], 'brain': [1948, 2010], 'sequential': [1951], 'chromatography': [1952, 2072], 'DE52,': [1954], 'hydroxylapatite,': [1955], 'ATP-agarose': [1957], 'described': [1959, 1986, 2013, 2076, 2139, 2191], 'previously': [1960, 1987, 2014, 2140, 2192, 3125], '(18.Greene': [1961], 'L.E.': [1962, 2146], 'Eisenberg': [1963, 1992, 2143], '265:': [1969], '6682-6687Abstract': [1970], 'Recombinant': [1977], 'Human': [1978, 2064, 2183], '(19.Rajapandi': [1988], 'T.': [1989], 'Wu': [1990], 'C.': [1991, 2142], 'Greene': [1994, 2145], 'L.': [1995], 'Biochemistry.': [1996], '37:': [1998], '7244-7250Crossref': [1999], '(20.Sullivan': [2015], 'Caucutt': [2019], 'Bartha': [2021], 'McMahon': [2023], 'Alnemri': [2025], 'E.S.': [2026], 'Litwack': [2027], '8007-8012Abstract': [2036], '(226)': [2044], 'except': [2047, 2723], 'passed': [2053], 'through': [2054], 'hydroxylapatite': [2056], 'column': [2057], 'twice': [2058, 2500], 'remove': [2060], 'any': [2061, 4873], 'contaminant': [2062, 3729], 'Hop.': [2063, 3044, 3117, 3168, 3534, 4781, 4887, 5398], 'bacterial': [2069, 4773], 'DE52': [2074], '(21.Johnson': [2077], '24989-24993Abstract': [2086], 'Fractions': [2093], 'identified': [2097], 'SDS-PAGE': [2099], 'pooled,': [2100], 'concentrated': [2101], 'ammonium': [2103, 2122], 'sulfate,': [2104, 2123], 'dialyzed': [2105], 'buffer': [2107, 2250, 2357, 2380, 2433, 2507, 2513, 2551, 2578, 4001], 'C': [2108], '(20': [2109], 'mmimidazole,': [2110], 'pH': [2111, 2255, 2361, 2385, 2444, 2556], '7.0,': [2112], '25': [2113, 2454, 2476, 2741, 2804, 3998, 4111, 4139, 4154, 4177, 4206, 4219, 5025, 5084], 'mm': [2114, 2117, 2121, 2253, 2258, 2359, 2364, 2367, 2383, 2435, 2438, 2442, 2448, 2452, 2455, 2459, 2510, 2516, 2554, 2561], 'KCl,': [2115, 2439], '2': [2116, 2120, 2542, 2628, 2748, 3023, 3151, 4193], 'magnesium': [2118, 2460], 'acetate,': [2119, 2461], '1': [2124, 2257, 2264, 2413, 2416, 2502, 2558, 2574, 2633, 2637, 2641, 2649, 2859, 2866, 3337, 3776, 3914, 4021, 4151], 'mmdithiothreitol),': [2125], 'aliquoted,': [2126, 2297], 'stored': [2128, 2300], '−70': [2130, 2302], '°C.': [2131, 2303, 2805, 4140, 4207, 5026], '(22.King': [2141], '22535-22540Abstract': [2152], '(55)': [2160], '23.Caplan': [2163], 'A.J.': [2164], 'Tsai': [2165], 'Casey': [2167], 'P.J.': [2168], 'Douglas': [2169], 'M.G.': [2170], '18890-18895Abstract': [2176], '(13.Johnson': [2193], 'B.D.': [2194], 'Schumacher': [2195], 'R.J.': [2196], 'Ross': [2197], 'E.D.': [2198], '3679-3686Abstract': [2206], '(298)': [2214], 'L929': [2217, 2330], 'mouse': [2218, 2644], 'fibroblast': [2219], 'grown': [2222], "Dulbecco's": [2224], 'modified': [2225], "Eagle's": [2226], 'medium': [2227], 'supplemented': [2228], '10%': [2230, 2369], 'fetal': [2231], 'serum.': [2233], 'Cells': [2234, 2276], 'washed': [2236, 2499, 2570], 'times': [2238, 2572, 4137], "Hanks'": [2240], 'balanced': [2241], 'saline': [2242], 'solution': [2243], 'suspended': [2245], '1.5': [2247], 'volumes': [2248], '10': [2252, 2382, 2463, 2553], 'Hepes,': [2254, 2384, 2436, 2555], '7.35,': [2256], 'EDTA,': [2259, 2368], '20': [2260, 2447, 2515, 2560, 3995, 4174], 'mmsodium': [2261], 'molybdate,': [2262, 2450], 'tablet': [2265], 'plus': [2271, 2563, 3335], '5': [2272, 2419, 2441, 2451, 2458, 2509, 3340, 3779], 'ml': [2273, 2503, 2575], 'buffer.': [2275], 'ruptured': [2278], 'Dounce': [2280], 'homogenization': [2281], 'centrifuged': [2283], '30': [2285, 2473, 2730], 'min': [2286, 2474, 3996, 4175], '37,000': [2288], 'rpm': [2289], 'prepare': [2291], 'cytosol.': [2293, 2603], 'supernatant': [2295], 'flash-frozen,': [2298], 'cell': [2305, 2331, 3973, 5373], 'Gordan': [2310], "Hager's": [2311], '(NCI,': [2313], 'National': [2314], 'Institutes': [2315], 'Health,': [2317], 'Bethesda,': [2318], 'MD).': [2319], '4': [2324, 2366, 2545, 3379, 3434, 4300], '°C': [2325, 2477, 2546, 2731, 2742, 3999, 4112, 4178, 4220], 'antibodies': [2338], 'prebound': [2339], 'A-Sepharose.': [2342], 'incubating': [2351, 2793], 'immune': [2353, 2597, 2610, 3981, 3989], 'pellets': [2354, 2388, 2482, 2497, 2532, 2611, 3982, 3990], 'TEG': [2356, 2379], '(10': [2358, 2434], 'TES,': [2360], '7.6,': [2362], '50': [2363, 2400, 2429, 2564], 'NaCl,': [2365, 2786, 3986], 'glycerol)': [2370], '0.5': [2372, 2784, 3984], 'm': [2373, 2785, 3985], 'NaCl': [2374], 'subsequent': [2376], 'washing': [2377], '7.4.': [2386], 'Immune': [2387, 2531], 'incubated': [2398, 2471, 2540, 2658, 2733, 2744, 3993, 4105, 4134, 4204, 4210, 4267, 4313, 4366], 'μl': [2401, 2430, 2549, 2601, 3970], 'mixtures': [2407, 2469], '(5': [2410], 'μm': [2411, 2414, 2417, 2420, 3338, 3341, 3777, 3780, 4017, 4022], 'if': [2424, 3595, 5073, 5161], 'necessary)': [2425], 'adjusted': [2427], 'HKD': [2432], '100': [2437, 2548, 2600, 3969], 'dithiothreitol,': [2443], '7.35),': [2445], 'sodium': [2449, 2517], 'creatine': [2456, 2465], 'phosphate,': [2457], 'units/ml': [2464], 'phosphokinase.': [2466], 'assay': [2468, 2605], 'suspension': [2479], 'shaking': [2484], 'tubes': [2486], 'rotator.': [2489], 'At': [2490], 'end': [2492, 3545, 3583, 3655], 'incubation,': [2495], 'ice-cold': [2505], 'TEGM': [2506, 2577], 'dithiothreitol': [2511], '(TEG': [2512], 'molybdate)': [2518], 'assayed': [2520, 2535], 'steroid-binding': [2522], 'capacity': [2523], 'and,': [2524, 3624, 4867], 'some': [2526], 'experiments,': [2527, 3316], 'receptor-associated': [2529, 3975], 'proteins.': [2530, 2890], 'h': [2543, 4152], '7.5,': [2557], 'mmEDTA,': [2559], 'nm[3H]triamcinolone': [2565], 'acetonide.': [2566], 'Samples': [2567], 'counted': [2580], 'liquid': [2582], 'scintillation.': [2583], 'expressed': [2588], 'counts/min': [2590], '[3H]triamcinolone': [2592], 'bound': [2594, 4246, 4261, 4385], 'per': [2595], 'pellet': [2598], 'resolved': [2613], '4–20%': [2615], 'SDS-polyacrylamide': [2616], 'gels': [2617], 'transferred': [2619], 'nitrocellulose': [2621], 'membranes.': [2622], 'membranes': [2624], 'probed': [2626], 'μg/ml': [2629, 2634, 2638, 2642, 2650], 'hsp90,': [2636], 'ascites': [2645], 'anti-Hsp40': [2652], 'antibody.': [2653], 'immunoblots': [2655], 'second': [2660, 4081, 4115], 'time': [2661], 'appropriate': [2664], 'peroxidase-conjugated': [2666], 'counter': [2667], 'antibody,': [2668, 5382], 'immunoreactive': [2670], 'visualized': [2673], 'ECL.': [2675], 'experiments': [2678, 3326, 3499], 'employed': [2689], 'essentially': [2690], 'procedure': [2693, 2762], 'used': [2694, 2760, 3312, 4771], 'overnight': [2734], 'hormone,': [2736], 'whereas': [2737], 'h.': [2749], 'difference': [2754, 4875, 4889], 'results': [2757, 2840, 3003, 3047, 3075, 3119, 3523, 3610, 4036, 4304, 4892, 5226], 'own.': [2765], 'BuGR2,': [2780], 'reconstituted': [2789, 2984, 4187, 4418], 'heterocomplex': [2791], 'routinely': [2807], '80–100%': [2809], 'restoration': [2810, 2879], 'activity': [2814, 2829, 2883, 4280, 4331, 4342, 4358, 5021, 5140, 5202, 5221], 'about': [2818, 2825, 3150, 3374, 3793, 3835, 5176], '50–60%': [2819], 'reconstitution': [2820, 2958, 3315, 4438, 4450, 4835, 4945, 5356], 'pure': [2822], 'i.e.': [2824], '60–65%': [2826], '(Fig.1,': [2833], 'B).': [2836], 'where': [2838], 'significantly': [2841, 2877, 4961], 'differ': [2842, 4852, 4960], 'those': [2844, 3018], "Pratt's": [2846, 2909], '(Fig.': [2858, 2865, 3022, 3120, 3323, 3378, 3433, 4298], 'A)': [2860, 3015], 'B),': [2867, 3024], 'did': [2875, 3629, 3930], 'occurred': [2899, 3824], 'even': [2900, 2981, 3390], 'p23.': [2905, 3190, 4234], 'As': [2906], 'observed': [2907, 4333], 'carried': [2964, 3318, 3328, 4090, 4291], 'out': [2965, 3319, 3329, 4091, 4292], 'necessary': [2974, 3081], 'because,': [2980], 'though': [2982], 'unstable': [2988], 'before': [2997, 4113], 'conformation': [3000, 4929], 'decays.': [3001], 'show': [3004], '(Fig.2': [3014], 'strongly': [3048, 3519], 'suggest': [3049, 4037, 5190], 'receptors;': [3059], 'binding.': [3072], 'still': [3089, 3450, 4158], 'possible': [3091, 4821, 4923], 'might': [3094, 4799, 5158], 'reactivation.': [3099], 'measured': [3102], '3)': [3121], 'half-life': [3148], 'min.': [3152], 'almost': [3162], 'identical': [3163], 'unnecessary': [3174], 'reactivation,': [3176], 'Hps90,': [3187], '6.Hutchison,': [3209, 4480, 4586], 'implies': [3223], 'approximately': [3225, 3827], 'equal': [3226, 3828, 5152, 5177], 'much': [3247, 3425, 4812, 5173], 'less': [3248, 3426, 3501, 3510, 3755, 3796, 3804], '1:1': [3256], 'molar': [3257], 'ratio': [3258], 'determine': [3293, 5344], '4).': [3324], 'These': [3325, 3638], '80': [3331, 3368, 3751], 'nm': [3332, 3369, 3376, 3430, 3758], 'present.': [3345], 'addition,': [3347], 'determined': [3349, 3725], 'Before': [3366], 'stripping,': [3367, 3412, 4094], 'contained': [3372, 3424, 3754], '0.4': [3375], 'B,': [3380], 'lane': [3381], '1)': [3382], 'agreement': [3384, 3903, 4236, 5223], 'studies,': [3387, 3815, 4239], 'suggesting': [3388, 3520], 'unstripped': [3391], 'contain': [3393], 'small': [3396, 3761, 3890], 'amount': [3397, 3762, 3891], 'since': [3400], 'appears': [3402], 'transiently': [3405], 'Following': [3411], 'undetectable': [3415, 3451], 'blotting': [3418], 'showing': [3419, 5236, 5273], '0.2': [3429], 'standard': [3432], 'B,lane': [3435], '9).': [3436], 'added': [3444, 4324], 'nor': [3452], 'detectable': [3455], 'Hsp90.': [3461, 3739, 3811, 4433], 'performed': [3464], 'experiment': [3466, 4086], 'baculovirus/Sf9': [3471], 'coli,': [3478], 'again': [3480], 'similar': [3483], 'levels': [3484, 3826, 5151], '0.25%': [3503], '0.1%': [3512, 3798], 'present,': [3518], 'due': [3526], '10-kDa': [3543, 3581, 3653], 'C-terminal': [3544, 3582, 3654], '(24.Demand': [3548, 3668], 'Luders': [3550, 3670, 3869], 'Hohfeld': [3552, 3672, 3871], '2023-2028Crossref': [3559, 3679, 3878], '(232)': [3562, 3682, 3881], 'assuming': [3566], 'similarly': [3572], 'regard,': [3575, 4954], 'missing': [3579], 'should': [3584], 'When': [3604], 'tested': [3606, 4122], 'prediction,': [3608], 'equally': [3618], 'furthermore,': [3625], 'case': [3628, 4915], 'significant': [3633, 3951, 4874], '(Fig.5).': [3637], 'data': [3639, 4789, 4825, 4851, 5189, 5235, 5272], 'provide': [3640], 'further': [3641], 'observation': [3687], 'reactivating': [3699], 'suggests': [3701], 'like': [3703, 3944], 'J-': [3705], 'may': [3708, 4897, 4911, 4932], 'little': [3711, 5290], 'investigate': [3720], 'question,': [3722], 'first': [3724, 4108, 4121, 4312], 'Hdj1': [3730, 3928], 'Based': [3740, 5269], 'Fig.6,': [3747], 'estimated': [3749], 'nmactive': [3752], '0.04': [3757, 3794], 'Hsp40.': [3759], 'This': [3760, 4888, 5229], 'removed': [3766, 4230], 'stripped.': [3771], 'upon': [3773], 'readdition': [3774], 'both,': [3783], 'returned': [3791], 'nm,': [3795], '0.01%': [3806], 'Since,': [3812], 'previous': [3814], 'maximum': [3817], 'one-tenth': [3836], '24.Demand': [3867], 'seems': [3885], 'unlikely': [3887], 'system': [3897], 'affected': [3898], 'view,': [3906], '0.25': [3912, 4016], 'μmYdj1': [3915], 'decreased': [3916], '(Fig.7).': [3923], 'Likewise,': [3924], '(data': [3937, 4164, 4253], 'shown).': [3939, 4166, 4255], 'find,': [3941], 'play': [3949, 4830, 5195], 'role': [3952, 4833, 4942, 5198], 'GR.Figure': [3957], '7Activation': [3958], 'Ydj1.GR': [3965], 'cytosol,': [3974], '(lane': [4002, 4005, 4014, 4018, 4023], '1);': [4003], '2);': [4006], '0': [4013], '3),': [4015], '4),': [4019], '5)': [4024], 'Ydj1.View': [4025], 'Large': [4026], 'Image': [4027], 'Figure': [4028], 'ViewerDownload': [4029], 'Hi-res': [4030], 'image': [4031], 'Download': [4032], '(PPT)': [4033], 'interested': [4060], 'whether,': [4063], 'following': [4064, 4093, 4144, 4334, 4345, 4965, 4998, 5014], 'one': [4068], 'receptor,': [4075, 5144, 5207, 5297], 'would': [4077], 'bound.': [4083], 'Such': [4084], 'if,': [4092], 'irreversibly': [4099, 4201], 'denature': [4100, 4202], 'while': [4101], 'being': [4104], 'added.': [4118], 'retains': [4127, 5008], 'incubation': [4145, 4168, 4285, 4337, 4346, 5023, 5082], '°C,': [4155, 5085], 'Similarly,': [4167], '(Fig.8,': [4191], 'lanes': [4192], 'and3).': [4194], 'next': [4209], 'unbound': [4231, 4316], 'completely': [4251], 'inactive': [4252], 'regained': [4276], 'particularly': [4281, 4912], 'initial': [4284, 4336], '8,lanes': [4299], '5).': [4302], 'Similar': [4303], 'removed,': [4318], 'ATP.': [4329, 4355, 4393], 'No': [4330], 'recovered': [4344, 4360], 'Interestingly,': [4356, 5096], 'more': [4357, 4381], 'because': [4379, 4973], 'somewhat': [4380], 'initially': [4384], 'earlier': [4435, 5188], 'studies': [4436, 4741, 5099, 5333], 'others': [4441], 'linked': [4553], 'complex,': [4559], '25.Kosano': [4666], 'functioned': [4694], 'unit': [4697], 'reconstitute': [4699, 4859], 'extract': [4774], 'clear': [4786], 'acted': [4792, 4809], 'expected': [4801, 5160], 'model,': [4805], 'lower': [4813, 5174], 'concentration.': [4814], 'latter': [4817], 'case,': [4818, 4848], 'suggest,': [4826], 'unique': [4832], 'playing': [4841], 'modulatory': [4843, 4941, 5197], 'role.': [4844], 'Even': [4845], 'however,': [4849], 'complete': [4863], 'moreover,': [4868], 'detect': [4872], 'related': [4899], 'fact': [4902], 'assume': [4906], 'multiple': [4907], 'conformations,': [4908], 'subtle': [4925, 4976], 'differences': [4926, 4977], 'account': [4933], 'plays': [4939], 'stripping': [4966, 4999, 5015], 'here,': [4974], 'too,': [4975], 'conformations': [4981], 'which': [4990], 'immediately': [4991], 'loses': [4992, 5019, 5030], 'substrate': [4997, 5013, 5093], 'reactivated,': [5004], 'slowly': [5018], 'once': [5028], 'cannot': [5038], 'reactivated.': [5040], 'shown': [5071, 5301], 'lose': [5091], 'ability.': [5095], 'although': [5126, 5186], 'along': [5132], 'maintain': [5138], 'stoichiometric': [5150], 'components': [5164], 'Rather,': [5168], 'concentrations,': [5175], 'concentration': [5180], 'maintaining': [5200, 5219], 'appear': [5211], 'primary': [5215], 'view': [5230], 'supported': [5233], 'yeast': [5239], 'propose,': [5299], 'Fig.9,': [5303], 'separate': [5310], 'sites': [5311], 'Future': [5332], 'mutant': [5335], 'hydrolysis': [5350], 'thank': [5362], 'Gordon': [5364], 'Hager': [5365], 'Barbour': [5368], 'Warren': [5369], 'cytosol;': [5374], 'anti-Hop': [5380]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1971562646', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 5}], 'updated_date': '2024-12-14T07:47:06.018299', 'created_date': '2016-06-24'}