Publication Information

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2134, 2149, 2157, 2189, 2210, 2248, 2300, 2370, 2403, 2429, 2449, 2568, 2619, 2639, 2778, 2781, 2795, 2870, 2879, 2907, 2935, 2960, 3010, 3036, 3040, 3075, 3109, 3130, 3155, 3180, 3231, 3256, 3260, 3270, 3286, 3311, 3332, 3341, 3396, 3426, 3430, 3465, 3491, 3556, 3656, 3807, 4062, 4068, 4108, 4116, 4125, 4135, 4146, 4203, 4502], '-resistant': [12, 191, 4126, 4503], 'components.': [13, 192], 'The': [14, 193, 372, 394, 418, 465, 509, 1329, 1375, 1451, 1726, 1796, 1923, 2010, 2077, 2089, 2146, 2230, 2267, 2356, 2414, 2434, 2454, 2467, 2484, 2538, 2599, 2607, 2624, 2644, 2921, 3533, 3635, 3709, 3824, 4006, 4510, 4529], 'former': [15, 194, 4548], 'caused': [17, 160, 196, 339, 471], 'by': [18, 110, 161, 197, 289, 340, 412, 425, 447, 458, 472, 614, 739, 843, 984, 1020, 1151, 1164, 1235, 1424, 1445, 1736, 1806, 2372, 2398, 2458, 2555, 2570, 2648, 2734, 2748, 2950, 3133, 3170, 3289, 3326, 3510, 3537, 3550, 3630, 3643, 3919, 3935, 4021, 4122, 4280, 4442, 4464], 'a': [19, 79, 198, 258, 383, 448, 461, 784, 963, 985, 1142, 1154, 1165, 1170, 1175, 1210, 1372, 1846, 1888, 1973, 2070, 2160, 2194, 2272, 2337, 2593, 2679, 2760, 2913, 2938, 2963, 3080, 3088, 3097, 3158, 3183, 3236, 3244, 3314, 3470, 3478, 3493, 3530, 3538, 3572, 3644, 3680, 3810, 3816, 3861, 3963, 4236, 4272, 4308, 4383, 4397, 4432], 'direct': [20, 199, 473, 1296], 'interaction': [21, 49, 163, 200, 228, 342, 474, 515, 1297], 'Ca2+channel': [23, 202], 'α1': [24, 203], 'subunits': [25, 204, 1440], 'with': [26, 50, 132, 205, 229, 311, 475, 562, 786, 797, 1169, 1264, 1623, 1738, 1808, 1893, 1908, 1960, 1979, 1993, 2014, 2020, 2067, 2155, 2222, 2235, 2252, 2271, 2320, 2362, 2380, 2488, 2531, 2542, 2815, 2936, 2958, 3024, 3096, 3156, 3178, 3243, 3312, 3415, 3517, 3672, 3734, 3809, 4444, 4545], 'Gβγ,': [27, 206], 'whereas': [28, 207, 934, 3600], 'the': [29, 40, 48, 51, 55, 61, 64, 85, 92, 99, 111, 119, 123, 130, 136, 143, 151, 155, 162, 165, 174, 208, 219, 227, 230, 234, 240, 243, 264, 271, 278, 290, 298, 302, 309, 315, 322, 330, 334, 341, 344, 353, 377, 514, 519, 528, 556, 565, 640, 712, 720, 771, 789, 795, 808, 907, 942, 975, 1015, 1029, 1033, 1124, 1131, 1135, 1146, 1160, 1181, 1189, 1196, 1217, 1222, 1230, 1299, 1303, 1307, 1315, 1334, 1339, 1382, 1435, 1528, 1604, 1617, 1633, 1643, 1652, 1659, 1745, 1788, 1818, 1822, 1897, 2045, 2080, 2083, 2094, 2099, 2166, 2218, 2353, 2366, 2459, 2470, 2476, 2509, 2546, 2649, 2658, 2727, 2730, 2742, 2753, 2770, 2776, 2784, 2791, 2798, 2810, 2816, 2839, 2843, 2850, 2853, 2856, 2863, 2874, 2880, 2886, 2947, 2969, 2980, 2983, 2992, 3006, 3049, 3057, 3071, 3167, 3189, 3214, 3227, 3253, 3263, 3268, 3323, 3342, 3359, 3366, 3369, 3378, 3392, 3435, 3440, 3443, 3448, 3461, 3498, 3504, 3541, 3546, 3551, 3560, 3587, 3590, 3601, 3604, 3618, 3622, 3631, 3638, 3641, 3647, 3651, 3661, 3673, 3692, 3703, 3713, 3726, 3729, 3745, 3759, 3765, 3770, 3784, 3827, 3830, 3851, 3877, 3882, 3885, 3887, 3890, 3904, 3907, 3910, 3920, 3940, 3943, 3951, 3957, 3969, 3975, 3985, 3989, 3997, 4002, 4015, 4094, 4099, 4105, 4111, 4129, 4143, 4218, 4222, 4225, 4230, 4233, 4242, 4254, 4262, 4266, 4269, 4281, 4285, 4313, 4321, 4324, 4329, 4346, 4387, 4400, 4403, 4406, 4411, 4414, 4417, 4439, 4467, 4485, 4492, 4514, 4534], 'latter': [30, 209], 'has': [31, 210, 427, 1225, 4010], 'not': [32, 211, 982, 1323, 2751, 3821, 4239, 4277, 4334], 'been': [33, 212, 428, 1226, 3582, 3822, 4011], 'characterized': [34, 213, 511], 'well.': [35, 214], 'Here,': [36, 215], 'we': [37, 216, 1200, 2789, 4097], 'show': [38, 217], 'that': [39, 60, 150, 218, 239, 329, 1129, 1141, 1159, 1295, 1325, 2945, 3165, 3321, 3617, 3844, 3906, 3929, 3984, 4253, 4453, 4499], 'N': [41, 76, 93, 134, 220, 255, 272, 313, 1530, 2471], 'terminus': [42, 53, 94, 101, 221, 232, 273, 280, 1531, 1535, 2472, 2479], 'Gαo': [44, 75, 80, 96, 133, 223, 254, 259, 275, 312, 1136, 1311, 1474, 1529, 1771, 1789, 2110, 2221, 2335, 2418, 2474, 2828, 3254, 4144, 4460], 'critical': [46, 225, 717], 'for': [47, 226, 513, 719, 932, 1134, 1314, 1324, 1434, 1454, 1811, 1821, 1842, 1896, 1910, 1931, 2001, 2057, 2176, 2245, 2317, 2377, 2412, 2431, 2451, 2528, 2575, 2621, 2641, 2841], 'C': [52, 100, 231, 279, 617, 1534, 1677, 2224, 2478, 3789, 4475], 'α1A': [56, 68, 89, 103, 112, 157, 171, 235, 247, 268, 282, 291, 336, 350, 775, 837, 935, 970, 1125, 1147, 1171, 1185, 1197, 1304, 1319, 1398, 1612, 1644, 1898, 2731, 2811, 2897, 2999, 3052, 3115, 3120, 3221, 3269, 3276, 3385, 3444, 3486, 3664, 3684, 3775, 3805, 3846, 3874, 3959, 3990, 4003, 4115, 4226, 4391, 4447], 'channel': [57, 113, 125, 145, 158, 170, 236, 292, 304, 324, 337, 349, 360, 380, 735, 811, 1148, 1198, 1305, 1320, 2732, 2757, 2893, 2898, 3116, 3121, 3272, 3277, 3776, 3847, 3948, 4004, 4019, 4118, 4227, 4392, 4448, 4471, 4539], 'subunit,': [58, 237, 1621, 1905, 2818], 'binding': [62, 131, 241, 310, 563, 721, 790, 1132, 1179, 2219, 2468, 4465], 'induces': [63, 242], 'voltage-resistant': [65, 86, 152, 244, 265, 331, 1016, 1143, 1182, 1193, 1316, 3655, 3999, 4255, 4440], 'inhibition.': [66, 245, 3634], 'An': [67, 246, 1968, 4336], 'C-terminal': [69, 114, 120, 166, 248, 293, 299, 345, 661, 1121, 1172, 1300, 2745, 2882, 3257, 3685, 3746, 3953, 3991, 4348], 'peptide,': [70, 249, 2724], 'an': [71, 250, 559, 1119, 1624, 2036, 2061, 2105, 2406, 2604, 2722, 2927, 3147, 3200, 3303, 3518, 3740, 4352], 'antiserum': [72, 251, 4282, 4311, 4338], 'raised': [73, 252, 1526, 4344], 'against': [74, 253, 1527, 2217, 2417, 4345], 'terminus,': [77, 135, 256, 314], 'N-terminal': [81, 175, 260, 354, 641, 1308, 1790, 2876, 3255, 4145], 'peptide': [82, 261, 1167, 1631, 2746, 3676, 3735, 3954, 3960, 3992], 'all': [83, 262], 'attenuated': [84, 263, 4217], 'currents.': [90, 269, 2894, 3117, 3273, 3848, 4228], 'Furthermore,': [91, 270], 'bound': [97, 276, 2520], 'to': [98, 277, 555, 788, 906, 938, 1228, 1371, 1390, 1603, 1629, 1658, 1671, 1744, 1782, 1817, 1998, 2035, 2054, 2074, 2118, 2144, 2153, 2180, 2352, 2374, 2405, 2475, 2521, 2572, 2603, 2768, 2782, 2838, 2912, 2918, 2942, 2956, 3046, 3139, 3162, 3176, 3295, 3318, 3358, 3543, 3596, 3606, 3715, 3720, 3739, 3772, 3829, 3856, 3892, 3897, 3977, 3996, 4013, 4140, 4142, 4287, 4331, 4355, 4416, 4516, 4521], 'in': [104, 129, 142, 283, 308, 321, 386, 441, 558, 807, 832, 972, 1026, 1216, 1238, 1443, 1500, 1547, 1664, 1732, 1802, 1845, 1881, 1887, 1906, 1934, 1972, 2159, 2336, 2564, 2578, 2759, 2855, 2862, 2910, 2962, 2979, 3005, 3048, 3070, 3182, 3226, 3339, 3365, 3391, 3439, 3460, 3540, 3559, 3603, 3637, 3660, 3666, 3702, 3712, 3725, 3744, 3769, 3804, 3826, 3845, 3869, 3873, 3881, 3889, 3939, 3966, 3974, 4025, 4199, 4221, 4232, 4268, 4284, 4293, 4299, 4328, 4413, 4438, 4446, 4491, 4513, 4542, 4547], 'vitro,': [105, 284], 'which': [106, 285, 442, 980, 1976, 2848, 3627, 3678, 3737, 3838, 4341, 4450], 'was': [107, 286, 1149, 1162, 1343, 1379, 1475, 1970, 1977, 2012, 2086, 2096, 2113, 2138, 2226, 2312, 2350, 2445, 2456, 2480, 2590, 2601, 2615, 2635, 2646, 2664, 2833, 3144, 3300, 3351, 3535, 3593, 3608, 3695, 3717, 3756, 3781, 3801, 3833, 3839, 3854, 3879, 3894, 3994, 4238, 4244, 4250, 4257, 4274, 4317, 4342, 4427, 4431, 4518], 'prevented': [108, 287, 1163], 'either': [109, 288, 1894, 2809, 3701, 4490], 'or': [115, 294, 612, 1901, 2068, 2325, 2348, 2812, 3705, 3767, 3972, 4326, 4494], 'GαoN-terminal': [116, 295], 'peptide.': [117, 296], 'Although': [118, 297, 4229], 'domain': [121, 167, 300, 346, 791, 1301, 3686, 3747], 'α1B': [124, 144, 303, 323, 421, 529, 713, 734, 798, 846, 927, 1027, 1127, 1327, 1407, 1620, 1653, 1902, 2744, 2756, 2779, 2892, 3064, 3271, 3455, 3749, 3785, 3870, 3930, 3947, 3952, 4066, 4117, 4470, 4538], 'showed': [126, 305, 4351, 4382], 'similar': [127, 306], 'ability': [128, 307], 'above': [137, 316, 2510], 'mentioned': [138, 317], 'treatments': [139, 318], 'were': [140, 319, 1422, 1441, 1460, 1537, 1655, 1730, 1772, 1800, 1829, 1883, 1926, 2047, 2151, 2171, 2201, 2233, 2269, 2358, 2396, 2425, 2486, 2523, 2540, 2553, 2655, 2924, 2954, 3044, 3174, 3334, 3434, 3527, 3932, 4137, 4507, 4541], 'ineffective': [141, 320], 'current.': [146, 325, 4005], 'These': [147, 326], 'findings': [148, 327, 3982], 'demonstrate': [149, 328, 1294], 'P/Q-type,': [156, 335], 'between': [164, 343, 1177, 1298, 2079, 2775, 3554], 'subunit': [172, 351, 530, 568, 714, 1342, 1456, 1613, 1645, 1654, 3750], 'region': [176, 355, 557, 1122, 1212, 1309, 1337], 'Gαo.': [178, 357], 'G-protein-coupled': [361, 415], 'receptor': [362, 1459, 1920, 2821, 4023], 'guanosine': [363], '5′-3-O-(thio)-': [364], 'triphosphate': [365], 'glutathioneS-transferase': [366, 1660], 'maltose-binding': [367], 'protein': [368, 615, 2589], 'polyacrylamide': [369, 2401, 2597], 'gel': [370, 2387, 2600], 'electrophoresis': [371, 2388], 'neuronal': [373], 'Cav2': [374], 'subclass': [375, 399], '(VDCC)1': [381], 'plays': [382], 'pivotal': [384], 'role': [385], 'triggering': [387], 'neurotransmitter': [388], 'release': [389], 'from': [390, 1344, 1477, 1539, 1832, 2196, 2204, 2902, 2916, 3031, 3125, 3137, 3281, 3293, 3421], 'nerve': [392], 'terminals.': [393], 'influx': [396], 'through': [397], 'this': [398, 1548, 2825, 3667], 'VDCC,': [401], 'pharmacologically': [402], 'designated': [403], 'as': [404, 436, 438, 1480, 1550, 1683, 2098, 2228, 2482, 2657, 3437, 3548, 4120, 4456, 4458], 'N-,': [405], 'P/Q-,': [406], 'R-type,': [408], 'negatively': [410], 'regulated': [411], 'neurotransmitters': [413], 'via': [414, 2739], 'receptors': [416, 2738, 2909, 3132, 3288], '(GPCRs).': [417], 'modulation': [419, 732], '(N-type,': [422], 'Cav2.2)': [423], 'GPCRs': [426, 844, 1021, 1236, 1263], 'extensively': [429], 'studied': [430], 'using': [431, 1462, 2666, 2671, 2806, 4128, 4550], 'exogenously': [432], 'expressed': [433, 835, 1731, 1801], 'cell': [434, 2011], 'models': [435], 'well': [437, 510, 4457], 'native': [439, 833, 1239, 4551], 'neurons,': [440], 'GPCR-mediated': [443, 772, 967, 2799], 'accompanied': [446, 3629, 3808], 'kinetic': [449, 3520, 3623], 'slowing': [450, 3521, 3534, 3624, 3812, 4264], 'activation': [452, 2735, 3626, 3814, 4267], 'can': [454], 'be': [455, 4462], 'largely': [456], 'relieved': [457, 983], 'application': [459, 3042, 3432, 4206], 'strong': [462, 930], 'depolarizing': [463, 3531, 3574, 3619, 3818], 'prepulse.': [464, 3025, 3081, 3237, 3471, 3532, 3730], 'component': [467, 4256], 'Gβγ': [476, 517, 553, 793, 3938], '(1Ikeda': [477], 'S.R.': [478], 'Nature.': [479, 500, 543, 581, 628, 918], '1996;': [480, 501, 604, 671, 863, 880], '380:': [481, 502], '255-258Crossref': [482], 'PubMed': [483, 504, 547, 585, 607, 632, 657, 679, 704, 765, 826, 866, 888, 902, 922, 957, 997, 1009, 1073, 1113, 1254, 1284, 1363, 1496, 1597, 1721, 2717, 4043, 4059, 4088, 4170, 4192, 4377, 4566], 'Scopus': [484, 505, 548, 586, 608, 633, 680, 705, 766, 827, 867, 889, 923, 958, 1010, 1074, 1114, 1255, 1285, 1364, 1598, 1722, 2718, 4044, 4089, 4193, 4378, 4567], '(709)': [485], 'Google': [486, 507, 550, 588, 610, 635, 658, 682, 707, 768, 829, 869, 891, 903, 925, 960, 998, 1012, 1076, 1116, 1257, 1287, 1366, 1497, 1600, 1724, 1759, 2720, 4046, 4060, 4091, 4171, 4195, 4380, 4569], 'Scholar,': [487, 683, 870, 892, 999, 1077, 4047, 4570], '2Herlitze': [488], 'S.': [489, 602, 699, 760, 815, 861, 1059, 1267, 1353, 4071, 4187, 4372], 'Garcia': [490], 'D.E.': [491], 'Mackie': [492], 'K.': [493, 754, 1057, 1087, 1271, 1347, 1571, 1695, 2691, 4075], 'Hille': [494], 'B.': [495], 'Scheuer': [496], 'T.': [497, 576, 1045, 1047, 1079, 1091, 1101, 1355, 1563, 1575, 1585, 1687, 1699, 1709, 2683, 2695, 2705], 'Catterall': [498], 'W.A.': [499], '258-262Crossref': [503], '(702)': [506], 'Scholar).': [508, 636, 769, 830, 904, 961, 1013, 1288, 1725, 1760, 4092, 4196], 'site': [512, 1384], 'cytosolic': [520], 'linker': [521], 'connecting': [522], 'domains': [523, 710], 'I': [524, 2008, 3794], 'II': [526], '(3DeWaard': [531], 'M.': [532, 570, 572, 819, 1051, 1061, 1085, 1095, 1099, 1273, 1277, 1349, 1569, 1579, 1583, 1693, 1703, 1707, 2689, 2699, 2703, 4077, 4081], 'Liu': [533], 'H.': [534, 1055, 1097, 1581, 1705, 2701], 'Walker': [535], 'D.': [536, 623, 687], 'Scott': [537], 'V.E.S.': [538], 'Gurnett': [539], 'C.A.': [540], 'Campbell': [541, 579], 'K.P.': [542, 580], '1997;': [544, 629, 701, 762, 899, 994, 1251, 1281, 4040, 4085, 4563], '385:': [545, 630], '446-450Crossref': [546], '(374)': [549], 'Scholar),': [551, 926, 1367, 1498, 2721, 4381], 'where': [552], 'binds': [554], 'exclusive': [560], 'manner': [561], 'VDCC': [566, 1037, 1234, 1412, 1911, 2223, 2477], 'β': [567], '(4Pragnell': [569], 'DeWaard': [571], 'Mori': [573, 1048, 1082, 1566, 1690, 2686], 'Y.': [574, 1049, 1053, 1083, 1089, 1567, 1573, 1691, 1697, 2687, 2693], 'Tanabe': [575], 'Snutch': [577, 595, 626, 854], 'T.P.': [578, 596, 627, 855], '1994;': [582, 1357, 4056], '368:': [583], '67-70Crossref': [584], '(552)': [587], 'Scholar,5Bourinet': [589], 'E.': [590, 621, 691, 849, 1803, 4150], 'Soong': [591, 850], 'T.H.': [592, 851], 'Stea': [593, 852], 'A.': [594, 603, 700, 761, 817, 853, 862, 1275, 1351, 4079, 4188, 4373], 'Proc.': [597, 694, 755, 856, 4182, 4367], 'Natl.': [598, 695, 756, 857, 4183, 4368], 'Acad.': [599, 696, 757, 858, 4184, 4369], 'Sci.': [600, 697, 758, 859, 4185, 4370], 'U.': [601, 698, 759, 860, 4186, 4371], '93:': [605, 864], '1486-1491Crossref': [606, 865], '(218)': [609, 868], 'Scholar)': [611, 659, 708, 1117, 1258, 1601, 4061], 'phosphorylation': [613, 746], 'kinase': [616], '(6Zamponi': [618], 'G.W.': [619], 'Bourinet': [620], 'Nelson': [622], 'Nargeot': [624], 'J.': [625, 652, 821, 897, 951, 992, 1004, 1062, 1102, 1249, 1279, 1487, 1586, 1710, 2706, 4038, 4054, 4083, 4161, 4177, 4362, 4561], '442-446Crossref': [631], '(406)': [634], 'In': [637, 2102, 2678, 2764, 2824, 3485, 3669, 3731, 3783, 3902, 4093], 'addition,': [638, 3903], 'both': [639, 1237, 4500], '(7Page': [642], 'K.M.': [643], 'Cantı́': [644], 'C.': [645], 'Stephens': [646], 'G.J.': [647], 'Berrow': [648], 'N.S.': [649], 'Dolphin': [650], 'A.C.': [651], 'Neurosci.': [653, 898, 993, 4055], '1998;': [654, 1006, 1065, 1105, 1589, 1713, 2709], '18:': [655], '4815-4824Crossref': [656], '(8Zhang': [662], 'J.-F.': [663, 872], 'Ellinor': [664, 873], 'P.T.': [665, 874], 'Aldrich': [666, 875], 'R.W.': [667, 669, 876, 878], 'Tsien': [668, 877], 'Neuron.': [670, 879, 1356], '17:': [672, 881, 900, 995], '991-1003Abstract': [673, 882], 'Full': [674, 676, 883, 885, 1068, 1070, 1108, 1110, 1360, 1493, 1592, 1594, 1716, 1718, 2712, 2714, 4167], 'Text': [675, 677, 884, 886, 1069, 1071, 1109, 1111, 1361, 1494, 1593, 1595, 1717, 1719, 2713, 2715, 4168], 'PDF': [678, 887, 1072, 1112, 1362, 1495, 1596, 1720, 2716, 4169], '(155)': [681, 890], '9Qin': [684], 'N.': [685, 1003, 1269, 4073], 'Platano': [686], 'Olcese': [688], 'R.': [689, 1081, 1093, 1565, 1577, 1689, 1701, 1754, 2685, 2697, 4160], 'Stefani': [690], 'Birnbaumer': [692], 'L.': [693], '94:': [702, 763], '8866-8871Crossref': [703], '(207)': [706], 'intracellular': [709, 2016, 3207, 4205], 'are': [715, 737, 801, 839], 'also': [716, 1023, 1139, 3718, 3840, 4519], 'sites': [718, 1133], 'regulatory': [723], 'action': [724], 'Gβγ.': [726], 'Some': [727], 'forms': [728], 'long-lasting,': [730], 'voltage-insensitive': [731], 'current': [736, 812, 2032, 2095, 2899, 3000, 3028, 3065, 3122, 3222, 3278, 3386, 3418, 3456], 'mediated': [738, 1019], 'more': [740, 1877, 4258], 'complex': [741], 'signaling': [742], 'pathways': [743], 'involving': [744], 'kinase-dependent': [745], '(10Diversé-Pierluissi': [747], 'M.A.': [748], 'Remmers': [749], 'A.E.': [750], 'Neubig': [751], 'R.R.': [752], 'Dunlap': [753], '5417-5421Crossref': [764], '(81)': [767], 'On': [770, 3942, 4469], 'regulation': [773, 813, 1038, 1232, 2774, 2800, 3662, 3945], '(P/Q-type,': [776], 'Cav2.1)': [777], 'channels,': [778, 799, 1028], 'although': [779], 'biochemical': [780, 1292], 'studies': [781, 4549], 'have': [782], 'demonstrated': [783], 'similarity': [785], 'respect': [787], 'affinity': [796], 'there': [800, 4316, 4430], 'many': [802], 'qualitative': [803], 'quantitative': [805], 'differences': [806], 'modes': [809], '(11Kaneko': [814], 'Akaike': [816, 1274, 4078], 'Satoh': [818, 1276, 4080], 'Jpn.': [820], 'Pharmacol.': [822, 1280, 4084], '1999;': [823], '81:': [824], '324-331Crossref': [825], '(21)': [828], 'Both': [831], 'cells,': [836, 4301], 'less': [840, 2859], 'strongly': [841], 'modulated': [842], 'than': [845, 1878, 2860, 3803, 3843, 3872, 4394], '(5Bourinet': [848], '8Zhang': [871], '12Currie': [893], 'K.P.M.': [894, 989], 'Fox': [895, 990], 'A.P.': [896, 991], '4570-4579Crossref': [901, 996], 'According': [905], 'willing': [908], 'reluctant': [909], 'model': [910], 'Gβγ-mediated': [912, 3867], '(13Bean': [916], 'B.P.': [917], '1989;': [919, 4189, 4374], '340:': [920], '153-156Crossref': [921], '(671)': [924], 'accept': [929], 'depolarization': [931, 986, 2915, 3136, 3292], 'opening,': [933], 'appear': [937], 'remain': [939], 'closed': [940], 'over': [941], 'physiological': [943], 'voltages': [944], '(14Colecraft': [945], 'H.M.': [946], 'Patil': [947], 'P.G.': [948], 'Yue': [949], 'D.T.': [950], 'Gen.': [952], 'Physiol.': [953, 1005], '2000;': [954], '115:': [955], '175-192Crossref': [956], '(55)': [959], 'Moreover,': [962], 'marked': [964, 3811], 'characteristic': [965], 'neurons': [973, 1240, 4029, 4552], 'dominance': [976, 3648], '“voltage-resistant”': [978], 'inhibition,': [979], 'prepulse': [987, 2073, 2081, 2941, 3161, 3317, 3575, 3620, 3645, 3779, 3819, 3878, 3908, 3923, 4130, 4237, 4249, 4273], '(12Currie': [988], '15Sun': [1000], 'Q.-Q.': [1001], 'Dale': [1002], '510:': [1007], '103-120Crossref': [1008], '(37)': [1011], 'Despite': [1014], 'being': [1018], 'its': [1024], 'presence': [1025, 2981, 3007, 3072, 3228, 3367, 3393, 3462, 3704, 3883, 4493], 'molecular': [1030, 1190], 'mechanism': [1031, 1191], 'underlying': [1032], 'different': [1034], 'mode': [1035], 'remains': [1039], 'unclear.': [1040], 'Recently,': [1041], 'Furukawaet': [1042], 'al.': [1043], '(16Furukawa': [1044], 'Nukada': [1046, 1100, 1354, 1584, 1708, 2704], 'Wakamori': [1050], 'Fujita': [1052], 'Ishida': [1054], 'Fukuda': [1056, 1270, 4074], 'Kato': [1058], 'Yoshii': [1060, 1098, 1348, 1582, 1706, 2702], 'Biol.': [1063, 1103, 1488, 1587, 1711, 2707, 4162], 'Chem.': [1064, 1104, 1489, 1588, 1712, 2708, 4163], '273:': [1066, 1106, 1590, 1714, 2710], '17585-17594Abstract': [1067], '(43)': [1075, 1256, 4045, 4568], '17Furukawa': [1078], 'Miura': [1080, 1564, 1688, 2684], 'Strobeck': [1084, 1568, 1692, 2688], 'Suzuki': [1086, 1570, 1694, 2690], 'Ogihara': [1088, 1572, 1696, 2692], 'Asano': [1090, 1574, 1698, 2694], 'Morishita': [1092, 1576, 1700, 2696], 'Hashii': [1094, 1578, 1702, 2698], 'Higashida': [1096, 1580, 1704, 2700], '17595-17603Abstract': [1107, 1591, 1715, 2711], '(53)': [1115, 1599, 1723, 2719], 'identified': [1118], 'equivalent': [1120, 2804, 3741, 3958, 4353], 'included': [1130], 'subunit.': [1137], 'They': [1138], 'found': [1140], 'increased': [1150], 'coexpression': [1152], 'Gαi/o': [1155, 1178, 1214], 'family': [1156], 'protein,': [1157], 'synthetic': [1166, 1206], 'PPQT1': [1168, 1557, 2794, 3677, 3961, 3993], 'sequence,': [1173], 'implying': [1174], 'relation': [1176], 'channels.': [1186, 1328, 3875], 'To': [1187], 'clarify': [1188], 'current,': [1199, 1321, 2007, 4449], 'used': [1201], 'function-blocking': [1202], 'anti-Gαi/o': [1203, 1223], 'antisera': [1204, 1224, 2147, 2996, 3061, 3218], '“decoy”': [1207], 'peptides': [1208, 1556, 3330, 3382, 3452], 'targeting': [1209], 'small': [1211], 'proteins': [1215, 1675, 1729, 1786, 1799, 2232, 2393, 2519], 'present': [1218, 4095], 'study.': [1219], 'One': [1220], 'shown': [1227, 3549, 4012, 4139, 4198], 'disrupt': [1229], 'negative': [1231], '(18Wiley': [1241, 4030, 4553], 'J.W.': [1242, 4031, 4554], 'Moises': [1243, 4032, 4555], 'H.C.': [1244, 4033, 4049, 4556], 'Gross': [1245, 4034, 4557], 'R.A.': [1246, 4035, 4558], 'Macdonald': [1247, 4036, 4052, 4559], 'R.L.': [1248, 4037, 4053, 4560], 'Neurophysiol.': [1250, 4039, 4562], '77:': [1252, 4041, 4564], '1338-1348Crossref': [1253, 4042, 4565], 'Xenopus': [1260, 1834], 'oocytes': [1261, 1876, 1925, 2046, 2170, 2807, 2858, 2903, 2970, 3032, 3126, 3190, 3282, 3354, 3422, 3670, 3732, 4064], 'coexpressing': [1262, 2808, 2904, 3033, 3127, 3283, 3423, 4065], 'VDCCs': [1265, 2802], '(19Kaneko': [1266, 4070], 'Yada': [1268, 4072], 'Kikuwaka': [1272, 4076], 'Br.': [1278, 4082], '121:': [1282, 4086], '806-812Crossref': [1283, 4087], '(12)': [1286, 4090], 'Our': [1289], 'electrophysiological': [1290, 2119, 2181], 'results': [1293], 'responsible': [1313], 'but': [1322, 4276, 4350], '1.1-kilobaseNcoI/HincII': [1330], 'fragment': [1331, 1378], 'excised,': [1332], 'containing': [1333, 1509, 1864, 1982, 2263], 'entire': [1335], 'coding': [1336, 1662], 'bovine': [1340, 1478, 2333], 'Gαo1': [1341, 1439, 1915, 4356], 'pGoα3': [1345], '(20Takao': [1346], 'Kanda': [1350], 'Kokubun': [1352], '13:': [1358, 1757], '747-755Abstract': [1359], '(71)': [1365], 'blunted': [1368], 'ligated': [1370, 1380], 'BamHI': [1373, 1383], 'adapter.': [1374], 'resulting': [1376], 'BamHI/BamHI': [1377], 'into': [1381, 1774, 2165, 2968, 3188, 3353], 'pSP64poly(A)': [1386], '(Promega,': [1387], 'Madison,': [1388], 'WI)': [1389], 'obtain': [1391], 'pGαoSP64poly(A).': [1392], 'Recombinant': [1393], 'plasmids': [1394], 'pSPCBI-2': [1395], '(rabbit': [1396, 1405], 'BI-2': [1397, 1611], 'subunit;': [1399, 1408, 1414], 'GenBankTM': [1400], 'accession': [1401], 'number': [1402], 'X57689),': [1403], 'pKCRB2': [1404], 'BIII': [1406, 1619], 'D14157),': [1409], 'pHCaB': [1410], '(human': [1411], 'β1b': [1413, 1455, 1912, 2817], 'AB054985),': [1415], 'pGαoSP64poly(A)': [1416], 'pKOPR': [1418], '(rat': [1419], 'κ-opioid': [1420, 1458, 1919, 2820, 2887, 2908, 2984, 3037, 3131, 3264, 3287, 3370, 3427, 4022], 'receptor;D16829)': [1421], 'linearized': [1423], 'XbaI,': [1425], 'SalI,': [1426], 'EcoRV,': [1427], 'EcoRI,': [1428], 'BstXI,': [1430], 'respectively.': [1431, 1472, 1554, 1795, 2213], 'cRNAs': [1432, 1453], 'specific': [1433], 'α1A,': [1436], 'α1B,': [1437], 'synthesized': [1442, 1461], 'vitro': [1444], 'SP6': [1446], 'RNA': [1447, 1466, 1895], 'polymerase': [1448, 1467], '(Invitrogen,': [1449], 'Groningen,': [1450], 'Netherlands).': [1452], 'T3': [1463], 'T7': [1465], '(Stratagene,': [1468], 'La': [1469], 'Jolla,': [1470], 'CA),': [1471], 'Purified': [1473], 'obtained': [1476, 1538], 'brains': [1479], 'descried': [1481], 'previously': [1482, 1685, 1748, 4138], '(21Sternweis': [1483], 'P.C.': [1484], 'Robishaw': [1485], 'J.D.': [1486, 4156], '1984;': [1490], '259:': [1491], '13806-13813Abstract': [1492], 'dissolved': [1499, 3335], '20': [1501, 1961, 1965, 2087, 2280, 2283, 2344, 2381, 2586, 2951, 3171, 3327, 3584], 'mm': [1502, 1505, 1511, 1514, 1851, 1854, 1857, 1860, 1880, 1941, 1944, 1947, 1952, 1955, 1984, 1987, 1990, 2275, 2278, 2281, 2302, 2492, 2499, 2502, 2505, 2566], 'Hepes,': [1503], '60': [1504], 'PO4-NaOH': [1506], '(pH': [1507], '8.0)': [1508, 2286], '0.1': [1510], 'EDTA,': [1512, 2276, 2500], '0.5': [1513, 1739, 2277, 2301], 'dithiothreitol,': [1515, 2279], '0.6%': [1517], 'sodium': [1518, 2384, 2506], 'cholate': [1519], 'stored': [1521], 'at': [1522, 1839, 1928, 2049, 2060, 2173, 2242, 2314, 2427, 2447, 2525, 2617, 2637, 2926, 3146, 3302, 3336, 3688, 4312], '−80': [1523], '°C.': [1524], 'Antisera': [1525, 2953, 3173], '(GC/2)': [1532], '(EC/2)': [1536], 'PerkinElmer': [1540], 'Life': [1541], 'Sciences': [1542], '(Boston,': [1543], 'MA)': [1544, 1781, 2411], 'represented': [1546, 2656], 'study': [1549, 2681, 4096], 'anti-Gαo(N)': [1551, 2148, 2347, 4310, 4479, 4532], 'anti-Gαo(C),': [1553], 'Synthetic': [1555, 3329], '(CHEDGLKDSPSWVTQRAQEM)': [1558], 'PB3T4': [1560, 2747, 2796, 3955], '(CQESGIKESVSWGTQRTQDV)': [1561], '(17Furukawa': [1562, 1686, 2682], 'corresponded': [1602, 3738], 'amino': [1605, 1638, 1647, 1764, 3689], 'acid': [1606, 1639, 1648, 1765, 1995, 3675], 'residues': [1607, 1640, 1649, 1766], '2028–2046': [1608], 'rabbit': [1610, 1618], '1931–1949': [1615], 'respectively,': [1622, 1682], 'extra': [1625], 'Cys': [1626], 'residue': [1627], 'added': [1628, 2351, 2563], 'each': [1630], 'on': [1632, 2797, 2885, 2997, 3062, 3111, 3219, 3262, 3383, 3453, 3650, 3758, 4110, 4320, 4386, 4402, 4410, 4533], 'N-terminal.': [1634], 'cDNA': [1635, 1761], 'fragments': [1636, 1762], 'encording': [1637], '1975–2424': [1641], '1912–2339': [1650], 'fused': [1656], 'in-frame': [1657], '(GST)': [1661], 'sequence': [1663, 3687], 'pGEX-2T': [1665], '(Amersham': [1666, 2239, 2464], 'Pharmacia': [1667, 2240, 2443, 2465, 2633], 'Biotech,': [1668], 'Uppsala,': [1669], 'Sweden)': [1670], 'produce': [1672, 1783], 'GST': [1673, 1727, 2324, 2326, 2517], 'fusion': [1674, 1728, 1785, 1798, 2327, 2518, 2536], 'termini,': [1678], 'GST-B1T': [1679], 'GST-B3T,': [1681], 'described': [1684, 1747], 'Escherichia': [1733], 'coli': [1734, 1804], 'DH5α': [1735, 1805], 'inducing': [1737], 'mmisopropyl-1-thio-β-d-galactoside': [1740, 1810], 'prepared': [1742, 2202], 'according': [1743, 1816], 'procedure': [1746], '(22Grieco': [1749], 'F.': [1750], 'Hay': [1751], 'J.M.': [1752], 'Hull': [1753], 'BioTechniques.': [1755], '1992;': [1756], '856-858PubMed': [1758], 'encoding': [1763], '1–88': [1767], '7–88': [1769], 'inserted': [1773], 'pMAL-c2X': [1775], 'vector': [1776], '(New': [1777, 2612], 'England': [1778, 2613], 'BioLabs,': [1779], 'Beverly,': [1780], 'MBP': [1784, 1797, 2535], 'domain,': [1791], 'MBP-Gαo-(1–88)': [1792], 'MBP-Gαo-(7–88),': [1794], 'induction': [1807], '0.3': [1809], '3': [1812, 2027], 'h': [1813, 2116, 2142, 2178, 2247, 2319, 2530, 2836, 2972, 3192, 3356, 4214], 'purified': [1815, 2332], 'instruction': [1819], 'manual': [1820], 'vector.': [1823], 'Small': [1824], 'pieces': [1825], 'ovarian': [1827], 'lobe': [1828], 'dissected': [1830], 'out': [1831, 2140], 'anesthetized': [1833], 'laevis': [1835], 'shaken': [1837], 'gently': [1838], '22': [1840, 1929, 2174], '°C': [1841, 1930, 2175, 2244, 2316, 2376, 2527, 2574], '90': [1843], 'min': [1844, 2379, 2577], 'solution': [1847, 1981, 2207], '(88': [1848, 1938], 'mmNaCl,': [1849, 1939, 2497], '1': [1850, 1853, 1879, 1940, 2211, 2432, 2452, 2498, 2504, 2529, 2622, 2642, 3565], 'KCl,': [1852, 1942], 'MgSO4,': [1855], '2.4': [1856, 1951], 'NaHCO3,': [1858, 1953], '7.5': [1859, 1954], 'Tris-HCl,': [1861, 1956, 2282, 2493], 'pH': [1862, 1957, 1999, 2285, 2494], '7.6)': [1863], '1.1': [1865], 'mg/ml': [1866, 2298], 'collagenase': [1867], '(Wako': [1868], 'Pure': [1869], 'Chemicals,': [1870], 'Osaka,': [1871], 'Japan).': [1872], 'Denuded,': [1873], 'healthy': [1874], 'looking': [1875], 'diameter': [1882], 'selected': [1884], 'injected': [1886, 1924, 2114, 2158, 2834, 2961, 2995, 3060, 3181, 3217, 3352, 3381, 3451], 'volume': [1889, 2161, 2257, 2339, 2964, 3184], '50': [1891, 1986, 2123, 2163, 2209, 2966, 3186, 3345, 4211], 'nl/cell': [1892], '(0.2': [1899, 1903, 1913], 'µg/µl)': [1900, 1904], 'combination': [1907], 'RNAs': [1909], 'µg/µl),': [1914, 1917], '(0.05': [1916], '(0.4': [1921], 'µg/µl).': [1922], 'incubated': [1927, 2172, 2234, 2313, 2430, 2450, 2524, 2620, 2640], '1–2': [1932], 'days': [1933], 'sterile': [1935], "Barth's": [1936], 'saline': [1937, 2262], '0.41': [1943], 'CaCl2,': [1945], '0.33': [1946], 'Ca(NO3)2,': [1948], '0.82': [1949], 'mmMgSO4,': [1950], '7.6,': [1958], 'supplemented': [1959], 'units/ml': [1962], 'penicillin,': [1963], 'µg/ml': [1966, 2291, 2294], 'streptomycin).': [1967], 'oocyte': [1969, 3349], 'placed': [1971], '50-µl': [1974], 'chamber': [1975], 'perfused': [1978], 'Ba50': [1980], '(50': [1983], 'Ba(OH)2,': [1985], 'Tris,': [1988], '2': [1989, 2293, 2971, 3191, 4213], 'KOH,': [1991], 'neutralized': [1992], 'methanesulfonic': [1994], 'adjusted': [1997], '7.4)': [2000], 'isolation': [2002], 'recording': [2004, 2840], 'Ba2+': [2006], 'Ba.': [2009], 'impaled': [2013], 'two': [2015, 4102], 'glass': [2017], 'electrodes': [2018], 'filled': [2019], '3m': [2021], 'KCl': [2022], '(for': [2023, 2031], 'voltage': [2024, 2771], 'monitor)': [2025], 'm': [2028], 'potassium': [2029], 'acetate': [2030], 'injection)': [2033], 'connected': [2034], 'amplifier': [2037], '(CA-1a;': [2038], 'Dagan,': [2039], 'New': [2040], 'York).': [2041], 'Unless': [2042], 'otherwise': [2043], 'noted,': [2044], 'clamped': [2048], '−60': [2050, 2917, 3138, 3294], 'mV': [2051, 2056, 2944, 3164, 3320], 'depolarized': [2053], '+20': [2055, 2919, 3140, 3296], '200': [2058, 2496], 'ms': [2059, 3579, 3585, 3724, 4292, 4298, 4525], 'interval': [2062, 2928, 3148, 3304], 'every': [2064], '30': [2065, 2305, 2556, 2579, 2930, 3150, 3306], 's,': [2066], 'without': [2069, 2933, 3087, 3153, 3309, 3407, 3477, 3529, 3915], 'preceding': [2071], '100-ms': [2072, 2940, 3160, 3316], '+100': [2075, 2943, 3163, 3319], 'mV.': [2076, 2920, 3141, 3297], 'duration': [2078], 'test': [2084, 2670, 2922, 2948, 3168, 3324, 3525, 3588], 'pulse': [2085, 2949, 3143, 3169, 3299, 3325], 'ms.': [2088, 2952, 3172, 3328, 3901], 'maximum': [2090], 'inward': [2091], 'deflection': [2092], 'measured': [2097], 'peak': [2100, 3505, 3544, 3607, 3716, 3773, 3831, 3893, 3970, 4332, 4407, 4418, 4517], 'amplitude.': [2101], 'some': [2103], 'experiments,': [2104], 'antisense': [2106, 2829], 'oligodeoxynucleotide': [2107, 2830], 'complementary': [2108], 'toXenopus': [2109], 'mRNA': [2111], '(5′-cccatgactgctcggggggg-3′)': [2112], '12–16': [2115, 2141, 2835], 'prior': [2117, 2143, 2179, 2837, 3357], 'measurements.': [2120, 2145, 2974, 3194, 3360], 'Injection': [2121], 'nl': [2124, 2164, 2967, 3187, 3346], '10': [2126, 2129, 2501, 2543, 2565, 3210], 'µm': [2127, 2130, 2136, 3338], 'PPQT1,': [2128, 2725], 'PB3T4,': [2131, 3736], '100': [2132, 2135, 2375, 2573, 3337, 3578], 'µmPGON1,': [2133], 'PGOC1': [2137, 3333], 'carried': [2139], 'anti-Gαo(C)': [2150, 2349, 4445], 'diluted': [2152, 2426, 2446, 2616, 2636, 2955, 3175], '1:50': [2154, 2957, 3177], 'water': [2156, 2959, 3179, 3340], 'oocytes.': [2167, 3941], 'Following': [2168], 'injection,': [2169], '2–3': [2177], 'recording.': [2182], 'GTPγS': [2183, 3203], '(Roche': [2184], 'Molecular': [2185], 'Diagnostics,': [2186], 'Basel,': [2187], 'Switzerland)': [2188], 'U50488H': [2190, 2986, 3372, 3500], '(trans-(±)-3,4-dichloro-N-methyl-N-(2-[1-pyrrolidinyl]cyclohexyl)benzeneacetamide': [2191], 'methanesulfonate': [2192], 'salt,': [2193], 'gift': [2195], 'Upjohn': [2197], 'Company,': [2198], 'Kalamazoo,': [2199], 'MI)': [2200], 'daily': [2203], 'frozen': [2205], 'stock': [2206], 'mm,': [2212], 'Competition': [2214], 'anti-Gαoantisera': [2216], 'termini': [2225], 'evaluated': [2227, 2481, 2665, 3536], 'follows.': [2229, 2483], 'solubilized': [2231], 'glutathione-Sepharose': [2236], '4B': [2237], 'beads': [2238, 2268, 2311, 2357, 2485, 2522, 2539], 'Biotech)': [2241, 2444, 2634], '4': [2243, 2315, 2321, 2329, 2526], '5': [2246, 2378, 2514, 2532, 2576], 'washed': [2249, 2359, 2541], 'five': [2250, 2360], 'times': [2251, 2361], '40': [2253, 2363], 'volumes': [2254, 2364, 2544], '(per': [2255], 'bed': [2256], 'resin)': [2259], 'phosphate-buffered': [2261], '1%': [2264], 'Triton': [2265], 'X-100.': [2266], 'equilibrated': [2270, 2310, 2487], 'buffer': [2273, 2368, 2490, 2548, 2560], '(0.1': [2274], 'mmNa2HPO4/NaH2PO4,': [2284], 'including': [2287, 2508], 'protease': [2288, 2511], 'inhibitors': [2289], '(2.5': [2290], 'pepstatin,': [2292], 'phenylmethylsulfonyl': [2295], 'fluoride,': [2296], '0.02': [2297], 'leupeptin,': [2299], 'benzamidine).': [2303], 'Approximately': [2304, 2513], 'µl': [2306, 2345, 2382, 2557, 2580, 2587], 'suspension': [2308], '12': [2318], 'µg': [2322, 2330, 2515, 2533], 'proteins,': [2328], 'brain': [2334], 'total': [2338], '500': [2341], 'µl.': [2342], 'Simultaneously,': [2343], 'reaction': [2354], 'mixture.': [2355], 'same': [2367, 2547, 3436, 4314], 'solutions': [2369, 2549, 2562], 'denatured': [2371, 2569], 'heating': [2373, 2571], 'dodecyl': [2385], 'sulfate-polyacrylamide': [2386], '(SDS-PAGE)': [2389], 'loading': [2390, 2583], 'buffer.': [2391, 2584], 'Denaturated': [2392], '(20': [2394, 2491], 'µl)': [2395], 'separated': [2397], 'SDS-PAGE': [2399, 2582], '(12%': [2400], 'gel)': [2402], 'transferred': [2404, 2602], 'Immobilon': [2407, 2605], 'membrane': [2408], '(Millipore,': [2409], 'Bedford,': [2410], 'immunoblotting.': [2413], 'primary': [2415, 2608, 4027], 'antibody': [2416, 2436, 2609, 2626], '(K-20;': [2419], 'Santa': [2420, 2422], 'Cruz,': [2421, 2423], 'CA)': [2424], '1:4,000': [2428, 2638], 'h.': [2433, 2453, 2623, 2643], 'second': [2435, 2625], '(horseradish': [2437, 2627], 'peroxidase-linked': [2438, 2628], 'anti-rabbit': [2439, 2629], 'goat': [2440], 'IgG,': [2441], 'Amersham': [2442, 2632], '1:2,000': [2448], 'detection': [2455, 2462, 2652], 'done': [2457], 'ECL': [2460, 2650], 'plus': [2461, 2651], 'system': [2463], 'Biotech).': [2466], 'column': [2489], '7.4,': [2495], 'β-mercaptoethanol,': [2503], 'azide)': [2507], 'inhibitors.': [2512], 'proteins.': [2537], 'after': [2550, 3199], 'incubation.': [2551], 'Proteins': [2552], 'eluted': [2554], 'elution': [2559], '(buffer': [2561], 'glutathione)': [2567], 'Each': [2585], 'loaded': [2591], 'onto': [2592], 'lane': [2594], 'SDS-12%': [2596], 'gel.': [2598], 'membrane.': [2606], 'anti-MBP': [2610], 'serum': [2611], 'Biolab)': [2614], '1:10,000': [2618], 'IgG': [2630], 'antibody,': [2631], 'immunoblot': [2645], 'detected': [2647], 'system.': [2653], 'Values': [2654], 'mean': [2659], '±': [2660, 3512, 3568, 3598, 3613, 3722, 3796, 3835, 3858, 3899, 3926, 4290, 4296, 4421, 4523], 'S.E.': [2661], 'Statistical': [2662], 'significance': [2663], 'ANOVA': [2667], 'andpost-hoc': [2668], 'Turkey': [2669], 'Prism': [2672], '3.01': [2673], '(GraphPad,': [2674], 'San': [2675], 'Diego,': [2676], 'CA).': [2677], 'previous': [2680], 'α1AC-terminal': [2723], 'reversed': [2726], 'currents': [2733, 2758, 3914, 4020, 4393, 4472, 4540], 'δ-opioid': [2737], 'Gαo1,': [2740], 'while': [2741], 'corresponding': [2743], 'itself': [2749], 'did': [2750], 'affect': [2752], 'mediation': [2761], 'Gαi3.': [2763], 'our': [2765], 'first': [2766], 'attempt': [2767], 'discriminate': [2769], 'dependence': [2772], 'αlA': [2777], 'characterize': [2783], 'specificity': [2785], 'decoy': [2787], 'peptides,': [2788, 3258], 'examined': [2790, 4121], 'effects': [2792, 2993, 3058, 3215, 3379, 3449, 4100, 4530], 'under': [2803], 'conditions': [2805], 'α1Bsubunit': [2813], 'together': [2814], 'Gαo1and': [2819], '(Fig.': [2822, 3488, 3787, 4132, 4473], '1).': [2823], 'experiment,': [2826], 'anti-Xenopus': [2827], '(5': [2831, 3204], 'µg)': [2832], 'minimizing': [2842], 'contribution': [2844], 'endogenous': [2846], 'Gαo,': [2847, 2906, 3035, 3129, 3285, 3425], 'reduced': [2849], 'magnitude': [2851, 3760], 'control': [2857, 3023, 3086, 3095, 3242, 3406, 3414, 3476], 'those': [2861, 3047, 3438, 4546], 'following': [2864], 'experiments': [2865], '(cf.': [2866], 'Figs.': [2867], '2,': [2868, 4201, 4474], '3,': [2869], '5).Figure': [2871], '2Effects': [2872], 'anti-Gαo': [2875, 2881, 3106], 'antiserum,': [2877, 2883, 4008], 'GC/2,': [2878, 4009], 'EC/2,': [2884, 3110, 4109], 'receptor-mediated': [2888, 3265], 'α1Aand': [2891], 'A,': [2895, 3118, 3274, 3566], 'representative': [2896, 3027, 3119, 3275, 3417], 'traces': [2900, 2976, 3029, 3123, 3196, 3279, 3362, 3419], 'recorded': [2901, 3030, 3124, 3280, 3420], 'α1Aβ1b,': [2905, 3128, 3284], 'response': [2911], 'step': [2914, 3135, 3291], 'pulses': [2923, 3526], 'applied': [2925, 3145, 3301, 3528, 3583, 3880], 's': [2931, 3151, 3307], 'alternately': [2932, 3152, 3308], '(left)': [2934, 3154, 3310], '(right)': [2937, 3157, 3313], 'conditioning': [2939, 3159, 3315], 'preceded': [2946, 3166, 3322], 'before': [2973, 3193, 3586, 4215], 'Superimposed': [2975, 3195, 3361], 'areI': [2977, 3197, 3363], 'Bas': [2978, 3198, 3364], 'agonist': [2985, 3371, 3921], '(1': [2987, 3373, 3501], 'µm).': [2988, 3374], 'B,': [2989, 3375, 4204], 'summary': [2990, 3055, 3212, 3376, 3446], 'U50488H-induced': [2998, 3063, 3384, 3454, 4219], '(n': [3002, 3067, 3388, 3514, 4526], '=': [3003, 3068, 3209, 3389, 3515, 3799, 4303, 4425, 4527], '4)': [3004, 3225, 3459, 3800, 4426], '(filled': [3008, 3073, 3229, 3394, 3463], 'column)': [3009, 3013, 3074, 3078, 3230, 3234, 3395, 3399, 3464, 3468], 'absence': [3011, 3076, 3232, 3397, 3466, 3706, 3727, 4234, 4270, 4495], '(open': [3012, 3077, 3233, 3398, 3467], 'prepulses.': [3015, 3401, 3708], '*,p': [3016], '<': [3017, 3021, 3084, 3092, 3240, 3403, 3411, 3474, 3698, 4435, 4482], '0.05;': [3018], '***,': [3019], 'p': [3020, 3083, 3091, 3239, 3410, 3473], '0.001versus': [3022], 'C,': [3026], 'α1Bβ1b,': [3034, 3424], 'receptors.': [3038, 3428], 'Recording': [3039, 3429], 'drug': [3041, 3431], 'procedures': [3043, 3433], 'identical': [3045], 'case': [3050, 3441], 'channel.': [3053], 'D,': [3054], '6)': [3069], '##,': [3082], '0.01versus': [3085], 'prepulse;': [3089, 3408], '**,': [3090], '0.01': [3093], 'versus': [3094, 3405, 3413], 'prepulse.View': [3098, 3245, 3479], 'Large': [3099, 3246, 3480], 'Image': [3100, 3247, 3481], 'Figure': [3101, 3248, 3482], 'ViewerDownload': [3102, 3249, 3483], '(PPT)Figure': [3103, 3250], '3Effects': [3104], 'antisera,': [3107], 'GC/2': [3108, 4107, 4134, 4208], 'GTPγS-induced': [3112, 3220], 'applying': [3134, 3290], 'Test': [3142, 3298], 'injection': [3201], 'pmol,': [3205], 'postulated': [3206], 'concentration': [3208, 3496], 'µm).B,': [3211], '(n=': [3224, 3458], '*,': [3238, 3409], '0.05versus': [3241, 3475], '5Effects': [3251], 'PGON1': [3259, 3331], 'PGOC1,': [3261], 'aliquot': [3343], '(∼10%': [3347], 'volume)': [3350], '15': [3355], '7–8)': [3390], '#,p': [3402], '0.05': [3404, 3412], 'prepulse.C,': [3416], 'channel.D,': [3445], '#,': [3472], '(PPT)': [3484], '1,': [3489, 3788], 'A': [3490, 4202], 'B),': [3492], 'maximally': [3494], 'effective': [3495], 'κ-agonist': [3499], 'µm)': [3502], 'inhibited': [3503, 3934], 'amplitude': [3506, 3642, 3652, 3766, 3832, 3911, 3971, 4223, 4325, 4408, 4419], 'ofI': [3507, 4488], 'Ba': [3508, 4489], 'reversibly': [3509], '15.0': [3511], '1.1%': [3513], '5)': [3516], 'apparent': [3519], 'activation,': [3523], 'when': [3524, 3815, 4248], 'delay': [3539, 3602, 3711, 3768, 3825, 3888, 3973, 4327, 4412, 4512], 'time': [3542, 3605, 3714, 3771, 3828, 3891, 3976, 4286, 4330, 4415, 4515], 'amplitude,': [3547], 'horizontal': [3552], 'difference': [3553], 'upward': [3555], 'downward': [3557], 'triangles': [3558], 'typical': [3561], 'trace': [3562], '(see': [3563], 'Fig.': [3564, 4200], '48.1': [3567], '6.2': [3569], 'ms).': [3570], 'When': [3571, 3876], 'large': [3573, 3817], '(+100': [3576], 'mV,': [3577], 'duration)': [3580], 'had': [3581, 3820], 'pulse,': [3589], 'agonist-induced': [3591, 3710, 3762, 3852, 4263, 4388, 4486, 4511], 'slightly': [3594], 'diminished': [3595, 3700], '13.0': [3597], '2.0%,': [3599], 'no': [3609, 3754, 4318], 'longer': [3610], 'observed': [3611, 3757], '(0.7': [3612], '1.2': [3614], 'ms),': [3615], 'indicating': [3616], 'eliminated': [3621], 'Gβγ-mediated,': [3632], 'decrease': [3636, 4014, 4437], 'suggested': [3646], '(87%': [3649], 'base)': [3653], 'kinetically': [3657], 'unaffected': [3658], 'condition.': [3668], 'preinjected': [3671, 3733], '20-amino': [3674], 'includes': [3679], 'part': [3681], 'predicted': [3683], 'acids': [3690, 3752], '2028–2046,': [3691], 'agonist-evoked': [3693], 'significantly': [3696, 3841, 4240, 4480], '(p': [3697, 4434, 4481], '0.05)': [3699, 4436], 'decreased': [3719, 3855, 4275, 4484, 4520], '12.4': [3721], '5.7': [3723], 'topological': [3742], 'position': [3743], '(amino': [3751], '1931–1949),': [3753], 'effect': [3755, 3965, 3987, 4319, 4385, 4401], 'currents,': [3777, 3949, 4119], 'whichever': [3778], 'protocol': [3780, 4131], 'used.': [3782], 'andD),': [3790, 4476], 'U50488H-evoked': [3791], 'Ba(44.8': [3795], '8.5%,': [3797], 'n': [3798, 4302, 4424], 'greater': [3802], 'applied.': [3823], '93.0': [3834], '12.8': [3836, 4291], 'ms,': [3837, 4423], 'larger': [3842, 3862], 'With': [3849], 'prepulse,': [3850, 4398, 4497], '27.3': [3857], '5.8%,': [3859], 'reflecting': [3860], '(40%)': [3863], 'portion': [3864], 'voltage-dependent,': [3866], 'agonist,': [3886], 'completely': [3895], 'abolished': [3896, 4279], '−5.9': [3898], '0.6': [3900], 'finding': [3905], 'potentiated': [3909], 'αlB': [3913], 'stimulation': [3916, 4024], 'κ-receptors': [3918, 4069], '(i.e.': [3922], 'facilitation,': [3924], '1.28': [3925], '0.06)': [3927], 'indicated': [3928], 'tonically': [3933], 'intrinsically': [3936], 'active': [3937], 'inhibitory': [3944], 'neither': [3950, 4399], 'nor': [3956, 4409], 'exerted': [3962], 'significant': [3964, 4245, 4433], 'terms': [3967], 'peak.': [3978], 'Taken': [3979], 'together,': [3980], 'these': [3981], 'indicate': [3983, 4452], 'blocking': [3986], 'preferential': [3995], 'Gαo-mediated,': [3998], 'anti-Gαo-N-terminal': [4007], 'N-type': [4018], 'rat': [4026], 'afferent': [4028], '23Moises': [4048], 'Rusin': [4050], 'K.I.': [4051], '14:': [4057], '3842-3851Crossref': [4058], 'inXenopus': [4063], 'compared': [4098], 'kinds': [4103], 'anti-Gαo-antisera,': [4106], 'κ-agonist-induced': [4112], 'separating': [4123], 'components': [4127, 4504], '2).': [4133], 'EC/2': [4136, 4339], 'bind': [4141], 'C-terminal,': [4147], 'respectively': [4148], '(24Padrell': [4149], 'Carty': [4151], 'D.J.': [4152], 'Moriarty': [4153], 'T.M.': [4154], 'Hildebrandt': [4155], 'Landau': [4157], 'E.M.': [4158], 'Iyengar': [4159], '1991;': [4164], '266:': [4165], '9771-9777Abstract': [4166], 'Scholar,25Simonds': [4172], 'M.F.': [4173, 4358], 'Goldsmith': [4174, 4359], 'P.K.': [4175, 4360], 'Codina': [4176, 4361], 'Unson': [4178, 4363], 'C.G.': [4179, 4364], 'Spiegel': [4180, 4365], 'A.M.': [4181, 4366], '86:': [4190, 4375], '7809-7813Crossref': [4191, 4376], '(310)': [4194, 4379], 'As': [4197], '(anti-Gαo(N),': [4209], '1:50-diluted,': [4210], 'nl/oocyte,': [4212], 'recording)': [4216], 'reduced,': [4241], 'reduction': [4243], '(p<': [4246], '0.001)': [4247], 'applied,': [4251], 'showing': [4252, 4498], 'selectively': [4259], 'suppressed.': [4260], 'Similarly,': [4261], 'fully': [4278], '(delay': [4283], 'peak:': [4288], '31.5': [4289], 'controls,': [4294], '11.4': [4295], '7.9': [4297], 'anti-Gαo(N)-injected': [4300], '4).': [4304], 'After': [4305], 'preinjection': [4306, 4477], 'heat-inactivated': [4309], 'dose,': [4315], '(data': [4333], 'shown).': [4335], 'anti-Gαo-C-terminal': [4337], '(anti-Gαo(C)),': [4340], 'originally': [4343], 'Gαi3': [4347], 'polypeptide': [4349], 'cross-reactivity': [4354], '(25Simonds': [4357], 'smaller': [4384], 'anti-Gαo(N).': [4395], 'Without': [4396], '(35.2': [4420], '15.5': [4422], 'significant.': [4428], 'However,': [4429], 'pretreatment': [4443], 'may': [4451, 4461], 'heterotrimeric': [4454], 'G-protein': [4455], 'free': [4459], 'immobilized': [4463], 'antibody.': [4468], '0.01)': [4483], 'simultaneously': [4508], 'attenuated.': [4509], '12.6': [4522], '4.3': [4524], '6).': [4528], 'good': [4543], 'keeping': [4544], '23Moise': [4571]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1971346487', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}], 'updated_date': '2025-01-13T07:36:12.674476', 'created_date': '2016-06-24'}