Title: Formation of glycerides with saturated and unsaturated fatty acids in rat-liver particles
Abstract: Abstract The incorporation into neutral glycerides of [1-14C]palmitic acid by mitochondrial and by microsomal enzyme systems of rat liver exceeded markedly that of stearic and linoleic acids. When the enzyme systems were supplied with mixtures of palmitic and oleic or with palmitic and linoleic acid, the incorporation of palmitic acid was depressed much beyond the dilution factor and the unsaturated fatty acids were preferred for triglyceride synthesis. The lower incorporation of linoleic acid into neutral glycerides, when supplied as the only acid, was due to the accumulation of its incorporation products in the “phospholipid fraction”, eluted by methanol from silicic acid columns. In the presence of linoleic acid carrier more [1-14C]palmitic acid was found in the “phospholipid fraction” than with palmitate as sole acid. The identity of the substances in the “phospholipid fraction” is discussed.
Publication Year: 1959
Publication Date: 1959-01-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 6
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