Publication Information

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'https://openalex.org/W2377355249', 'https://openalex.org/W2114940471', 'https://openalex.org/W2112707168', 'https://openalex.org/W2066804170', 'https://openalex.org/W2011333117', 'https://openalex.org/W1507055266'], 'abstract_inverted_index': {'Angiotensin': [0, 179, 938], 'II': [1, 180, 939], '(AII)': [2, 181, 940], 'increases': [3, 144, 182, 323, 3942, 5488], 'production': [4, 183, 3943], 'of': [5, 30, 56, 82, 90, 108, 115, 158, 184, 209, 235, 261, 269, 287, 294, 337, 400, 435, 441, 525, 704, 772, 909, 912, 916, 931, 956, 967, 1115, 1150, 1172, 1179, 1206, 1214, 1225, 1229, 1622, 1670, 1677, 1690, 1733, 1748, 1750, 1811, 1913, 1955, 1967, 1984, 2039, 2099, 2170, 2222, 2356, 2527, 2571, 2586, 2630, 2662, 2719, 2778, 2808, 2911, 2916, 2930, 2935, 3003, 3007, 3046, 3084, 3098, 3108, 3256, 3290, 3367, 3377, 3385, 3418, 3423, 3474, 3479, 3487, 3504, 3518, 3523, 3528, 3546, 3553, 3612, 3615, 3629, 3640, 3644, 3669, 3681, 3702, 3709, 3772, 3778, 3793, 3806, 3837, 3858, 3880, 3892, 3903, 3944, 3961, 4056, 4127, 4148, 4153, 4156, 4179, 4232, 4241, 4325, 4344, 4358, 4381, 4399, 4409, 4534, 4537, 4548, 4553, 4567, 4577, 4580, 4649, 4667, 4808, 4817, 4879, 4889, 4893, 4986, 5085, 5132, 5207, 5216, 5223, 5233, 5261, 5282, 5285, 5292, 5318, 5355, 5360, 5469, 5473, 5481, 5499], 'reactive': [6, 185, 361, 370, 542, 762], 'oxygen': [7, 186, 362, 371], 'species': [8, 187, 363], 'from': [9, 136, 188, 315, 1105, 1258, 1269, 1288, 1294, 1299, 1307, 1320, 1331, 1349, 1358, 1369, 1379, 1392, 1412, 1514, 1659, 2604, 3064, 3281, 3580, 3646, 3947, 4334, 5537], 'NAD(P)H': [10, 137, 189, 316, 957, 1106, 1207, 3065, 3067, 3100, 3282, 3948, 4194, 4335], 'oxidase,': [11, 190, 958, 1208, 3949], 'a': [12, 40, 92, 116, 167, 191, 219, 271, 295, 346, 680, 694, 761, 959, 965, 1109, 1189, 1601, 1924, 2175, 2410, 2514, 2622, 2877, 3016, 3665, 3763, 3818, 4137, 4550, 4678, 4804, 4984, 5306, 5470, 5497], 'response': [13, 176, 192, 355, 3724], 'that': [14, 28, 134, 164, 171, 193, 207, 313, 343, 350, 610, 777, 891, 961, 1102, 1124, 1137, 1221, 1238, 1951, 3096, 3402, 3408, 3564, 3803, 3925, 3940, 4043, 4228, 4332, 4512, 4639, 4685, 4727, 4746, 4794, 4815, 5111, 5205, 5219, 5258, 5312, 5335, 5370, 5422, 5465, 5484, 5492, 5504, 5516], 'contributes': [15, 154, 194, 333, 1239], 'to': [16, 86, 148, 155, 177, 195, 265, 327, 334, 356, 534, 606, 617, 685, 687, 690, 716, 783, 790, 964, 1131, 1240, 1627, 1663, 1908, 1928, 1981, 2007, 2013, 2162, 2179, 2231, 2349, 2360, 2422, 2518, 2593, 2689, 2770, 2799, 2944, 3252, 3258, 3515, 3573, 3688, 3725, 3811, 3827, 3854, 3856, 4059, 4135, 4144, 4214, 4498, 4510, 4647, 4790, 4997, 5036, 5122, 5309, 5327, 5450, 5520], 'vascular': [17, 24, 196, 203, 429, 942, 968, 3956, 3962], 'hypertrophy.': [18, 197, 4146], 'Here': [19, 198], 'we': [20, 199, 1184, 1949, 3863, 4203, 4317, 4368, 4875], 'show': [21, 133, 200, 312, 4331, 4638], 'in': [22, 43, 69, 173, 201, 222, 248, 352, 711, 768, 786, 1112, 1167, 1243, 1594, 1723, 1757, 1797, 1817, 1917, 1939, 2085, 2118, 2139, 2426, 2611, 2666, 2701, 2728, 2738, 2756, 2775, 2780, 2810, 2817, 2876, 2947, 2951, 3031, 3116, 3250, 3415, 3435, 3484, 3492, 3510, 3588, 3664, 3699, 3723, 3821, 3846, 3871, 3955, 4140, 4165, 4262, 4393, 4407, 4501, 4504, 4523, 4582, 4693, 4733, 4738, 4806, 5099, 5134, 5168, 5194, 5275, 5378, 5436, 5454, 5477], 'cultured': [23, 202, 1416], 'smooth': [25, 204, 430, 943, 1132, 4741], 'muscle': [26, 205, 431, 944, 1133, 4742], 'cells': [27, 206, 669, 712, 1470, 1597, 1738, 1794, 1898, 2128, 2369, 2416, 2428, 2482, 2787], 'S-glutathiolation': [29, 55, 208, 234, 377, 703, 930, 2804, 3475, 4130, 4159, 5299, 5359], 'the': [31, 35, 50, 54, 67, 79, 106, 156, 174, 210, 214, 229, 233, 246, 258, 285, 335, 353, 508, 530, 541, 672, 769, 913, 1113, 1138, 1143, 1151, 1159, 1193, 1235, 1241, 1553, 1560, 1573, 1607, 1610, 1620, 1691, 1725, 1734, 1789, 1793, 1809, 1812, 1855, 1910, 1936, 1961, 2097, 2127, 2181, 2211, 2423, 2494, 2509, 2595, 2605, 2612, 2641, 2647, 2660, 2663, 2698, 2702, 2720, 2776, 2914, 3001, 3004, 3029, 3082, 3099, 3254, 3365, 3375, 3416, 3431, 3472, 3477, 3490, 3502, 3508, 3516, 3544, 3613, 3630, 3678, 3703, 3791, 3804, 3822, 3847, 3959, 4044, 4053, 4125, 4151, 4154, 4199, 4226, 4260, 4363, 4382, 4394, 4521, 4535, 4546, 4554, 4575, 4578, 4657, 4818, 4862, 4866, 4877, 4991, 5069, 5192, 5214, 5220, 5230, 5283, 5289, 5315, 5319, 5353, 5420, 5431, 5466, 5479, 5528], 'redox-sensitive': [32, 168, 211, 347, 604, 1170, 1199, 3310, 3823, 4054, 4141, 4352, 4528, 4540, 4584, 4597, 5341, 5452], 'Cys118': [33, 117, 142, 212, 296, 321, 398, 778, 932, 1212, 3683, 4132, 4216, 4390, 4489, 5209], 'on': [34, 141, 213, 320, 522, 544, 933, 2019, 2646, 2659, 3052, 3297, 3536, 3555, 3603, 3673, 3684, 3917, 4366, 4515, 4665, 4887, 4972], 'small': [36, 215, 753], 'GTPase,': [37, 216, 754], 'Ras,': [38, 217, 397, 755, 3008, 3480, 4367], 'plays': [39, 218, 1108, 3817, 4803], 'critical': [41, 220, 1110, 3819, 4138, 5263, 5471], 'role': [42, 221, 728, 1111, 3820, 3954, 4805], 'AII-induced': [44, 223, 1162, 2803, 2948, 3055, 3674, 4145, 4640, 5107], 'hypertrophic': [45, 224, 1152, 1200, 3117, 3311, 4541, 5521], 'signaling.': [46, 225, 3260, 4585], 'AII': [47, 226, 2344, 2419, 2745, 2851, 2875, 3049, 3087, 3105, 3259, 3314, 3371, 3558, 3726, 3782, 3797, 3848, 3908, 3921, 3941, 4063, 4266, 4502, 4571, 4595, 4686, 4737, 4750, 4826, 4967, 5119], 'simultaneously': [48, 227], 'increased': [49, 228, 2814, 2854, 2873, 2886, 3023, 4045, 4230, 5129, 5164, 5221, 5500], 'Ras': [51, 57, 87, 99, 119, 230, 236, 266, 278, 298, 787, 898, 917, 934, 1215, 1226, 1253, 1385, 1650, 1655, 1660, 1697, 1711, 1846, 2022, 2475, 2592, 2599, 2631, 2741, 2809, 3009, 3020, 3032, 3047, 3058, 3085, 3268, 3389, 3493, 3556, 3577, 3604, 3645, 3671, 3685, 3705, 3774, 4128, 4157, 4182, 4247, 4345, 4411, 4524, 4559, 4581, 4659, 4728, 4755, 4992, 5086, 5133, 5170, 5195, 5208, 5217, 5225, 5474], 'activity': [52, 70, 146, 231, 249, 325, 788, 1851, 2742, 3012, 3021, 3033, 3494, 3511, 4408, 4525, 5002, 5196, 5222, 5325, 5354, 5377, 5425], 'and': [53, 71, 102, 105, 123, 143, 150, 232, 250, 281, 284, 302, 322, 329, 596, 760, 789, 949, 974, 1126, 1142, 1174, 1176, 1198, 1211, 1231, 1247, 1250, 1265, 1281, 1313, 1338, 1343, 1387, 1407, 1481, 1483, 1506, 1585, 1598, 1683, 1699, 1882, 1997, 2005, 2021, 2037, 2137, 2210, 2363, 2377, 2405, 2493, 2534, 2568, 2578, 2607, 2619, 2638, 2654, 2687, 2740, 2754, 2785, 2805, 2903, 2937, 3057, 3267, 3292, 3382, 3391, 3441, 3495, 3530, 3572, 3586, 3598, 3601, 3619, 3627, 3697, 3711, 3761, 3769, 3851, 3860, 3894, 3899, 3905, 3958, 4049, 4177, 4186, 4189, 4217, 4236, 4246, 4256, 4259, 4316, 4342, 4356, 4372, 4379, 4397, 4526, 4562, 4565, 4635, 4652, 4810, 4861, 4891, 4895, 4963, 5033, 5079, 5082, 5096, 5114, 5162, 5166, 5357, 5447, 5506, 5514, 5535], '(GSS-Ras)': [58, 237], 'detected': [59, 238, 2244, 2633, 2820, 2847], 'by': [60, 111, 239, 290, 438, 511, 537, 594, 954, 1135, 1169, 1666, 1674, 1688, 1703, 1714, 1854, 1894, 1934, 1943, 2025, 2074, 2096, 2245, 2575, 2634, 2744, 2748, 2821, 2848, 2874, 3036, 3048, 3062, 3086, 3104, 3279, 3313, 3370, 3374, 3395, 3430, 3439, 3499, 3557, 3568, 3584, 3594, 3781, 3796, 3814, 3831, 3841, 3875, 3897, 3907, 3920, 4062, 4129, 4158, 4169, 4212, 4225, 4265, 4321, 4346, 4490, 4530, 4570, 4594, 4736, 4749, 4754, 4758, 4825, 4869, 4966, 4978, 5118, 5198, 5347, 5384, 5419, 5444, 5512, 5524], 'biotin-labeled': [61, 240], 'GSH': [62, 241, 670, 2035, 2070, 2082, 2110, 3440, 3442, 3570, 5293, 5350, 5375, 5423, 5448], 'or': [63, 95, 242, 274, 468, 570, 707, 710, 713, 723, 2732, 2918, 3216, 3263, 3286, 3362, 3634, 3660, 4239, 4386, 4590, 4669, 5269, 5303], 'mass': [64, 243, 2636, 2667, 2675, 3596, 3637, 3815, 4175, 4370, 4491], 'spectrometry.': [65, 244], 'Both': [66, 245], 'increase': [68, 247, 785, 1242, 2665, 2737, 2779, 3030, 3491, 3509, 4261, 4406, 4522], 'GSS-Ras': [72, 140, 165, 251, 319, 344, 1196, 2242, 2739, 2855, 2871, 2887, 2891, 2912, 2931, 3043, 3056, 3078, 3266, 3403, 3496, 3505, 3565, 3833, 3872, 3918, 3926, 4233, 4244, 4340, 4513, 4538, 4795, 4890, 4973, 4976, 5113, 5486, 5493], 'was': [73, 252, 1292, 1297, 1329, 1356, 1367, 1377, 1566, 1576, 1592, 1613, 1630, 1651, 1657, 1672, 1712, 1820, 1852, 1892, 1921, 1971, 2017, 2023, 2072, 2114, 2172, 2214, 2243, 2347, 2358, 2396, 2407, 2529, 2548, 2560, 2573, 2588, 2602, 2609, 2746, 2768, 2797, 2872, 2892, 3013, 3022, 3034, 3248, 3482, 3533, 3578, 3617, 3686, 3809, 4133, 4172, 4543, 4995, 5226], 'labile': [74, 253], 'under': [75, 254], 'reducing': [76, 255, 5430], 'conditions,': [77, 256], 'suggesting': [78, 257, 3040, 3407, 5110], 'essential': [80, 259], 'nature': [81, 260], 'this': [83, 262, 903, 1182, 4123, 4320, 4400, 4516, 4691, 5262, 5460], 'thiol': [84, 263, 718, 1223, 1911, 2165, 3005, 5336, 5472], 'modification': [85, 264, 904, 1224, 3006, 3805, 5468], 'activation.': [88, 267, 1914, 5075, 5124], 'Overexpression': [89, 268, 3384, 3486, 3701, 3771, 4147], 'catalase,': [91, 270, 3285, 4650], 'dominant-negative': [93, 272, 415, 1507], 'p47phox,': [94, 273, 3103], 'glutaredoxin-1': [96, 275, 1209], 'decreased': [97, 120, 276, 299, 2904, 3077, 3265, 3288, 3526, 3707, 3776, 5106], 'GSS-Ras,': [98, 277, 3388, 5513], 'activation,': [100, 279, 4560], 'p38,': [101, 280, 381, 1116, 1341], 'Akt': [103, 124, 151, 282, 303, 330, 1175, 1232, 2919, 3293, 3531, 3712, 3895, 3906, 4187, 4257, 4563, 4964, 5078, 5108, 5123, 5507], 'phosphorylation': [104, 125, 283, 304, 2915, 3097, 3289, 3299, 3527, 3708, 3777, 3857, 3891, 3902, 4188, 4258, 4642, 4666, 4807, 4892, 4965, 5081], 'induction': [107, 157, 286, 336, 3366, 3545, 3792, 4357, 4566], 'protein': [109, 129, 159, 288, 308, 338, 384, 571, 688, 1244, 1263, 1273, 1970, 2171, 2395, 2532, 2544, 2600, 2608, 2699, 2949, 3368, 3547, 3721, 3794, 4190, 4263, 4359, 4552, 4568, 4759, 5328], 'synthesis': [110, 289, 2950, 3369, 3548, 3722, 3795, 4191, 4264, 4569], 'AII.': [112, 178, 291, 357, 1494, 3832, 3876, 4170, 4531, 5525], 'Furthermore,': [113, 292], 'expression': [114, 293, 1661], 'mutant': [118, 297, 3706, 3787, 4181, 4660, 4994, 5070], 'AII-mediated': [121, 300], 'p38': [122, 149, 301, 328, 382, 1125, 1144, 1173, 1230, 2917, 2936, 3291, 3529, 3710, 4048, 4185, 4255, 4561, 4668, 4809, 5080, 5505], 'as': [126, 128, 305, 307, 433, 679, 721, 971, 1188, 1420, 1500, 1653, 2705, 2819, 2827, 2894, 2896, 3079, 3081, 3372, 4160, 4162, 4267, 4654, 4656, 4677], 'well': [127, 306, 2696, 3080, 3938, 4161, 4207, 4655], 'synthesis.': [130, 160, 309, 339, 1245, 4360], 'These': [131, 310, 3800, 4251, 4786, 5187], 'results': [132, 311, 2725, 3308], 'H2O2': [135, 314, 2882, 4229], 'oxidase': [138, 317, 1107, 3068, 3101, 4195, 4336], 'forms': [139, 318], 'its': [145, 324, 936, 4163], 'leading': [147, 326, 782, 4058, 4143], 'phosphorylation,': [152, 331, 4564, 5109], 'which': [153, 332, 512, 678, 1558, 1724, 3112, 3434, 3808, 3825, 3950, 4348, 4870, 5277], 'This': [161, 340, 1563, 2926, 4221, 5256, 5414], 'study': [162, 341, 1183, 4124, 5461], 'suggests': [163, 342, 2927, 5204, 5257], 'is': [166, 345, 517, 671, 682, 3050, 3405, 3427, 3437, 3566, 3762, 3852, 3869, 3928, 3936, 4196, 4206, 4223, 4349, 4391, 4402, 4494, 4508, 4518, 4587, 4596, 4643, 4682, 4751, 4796, 4865, 4982, 5475, 5494], 'signaling': [169, 348, 437, 516, 758, 792, 1201, 3118, 3276, 3312, 3849, 4057, 4142, 4168, 4353, 4503, 4529, 4542, 5094, 5362, 5438, 5453, 5522], 'switch': [170, 349], 'participates': [172, 351, 3845], 'cellular': [175, 354, 436, 515, 726, 5101], 'Considerable': [358], 'evidence': [359], 'implicates': [360], '(ROS)': [364], '1The': [365], 'abbreviations': [366], 'used': [367, 1618, 2589], 'are:': [368], 'ROS,': [369, 3109], 'species;': [372], 'AII,': [373, 3500, 4347, 5482, 5490], 'angiotensin': [374], 'II;': [375], 'GSS-,': [376], 'of;': [378], 'diamide,': [379], 'N,N,N′,N′-tetramethylazodicarboxamide;': [380], 'mitogen-activated': [383, 391], 'kinase;': [385, 389, 393], 'ERK,': [386, 1342], 'extracellular': [387], 'signal-regulated': [388], 'MEK,': [390], 'protein/ERK': [392], 'GRX,': [394, 3433, 5356, 5446], 'glutaredoxin;': [395], 'C118S': [396, 1649, 1710, 3670, 3704, 3773, 3786, 4180, 4658, 4993], 'mutation': [399, 1213, 1700], 'Ras;': [401], 'EGF,': [402, 3898], 'epidermal': [403], 'growth': [404, 445, 1310, 5038], 'factor;': [405], 'DPI,': [406, 3284], 'diphenyleneiodonium': [407, 3070], 'chloride;': [408], 'FBS,': [409], 'fetal': [410, 1401], 'bovine': [411, 1402, 1940], 'serum': [412, 1403, 1941], 'albumin;': [413], 'DN-p47phox,': [414, 4651], 'p47phox': [416, 1508], '(S303A/S304A': [417], 'double-mutant': [418], 'p47phox);': [419], 'DTT,': [420], 'dithiothreitol;': [421], 'MALDI-TOF,': [422], 'matrix-assisted': [423], 'laser': [424], 'desorption': [425], 'ionization': [426], 'time-of-flight;': [427], 'VSMC,': [428, 3582], 'cell.': [432], 'mediators': [434, 2941], 'several': [439], 'kinds': [440], 'stimuli,': [442], 'including': [443, 3110, 5364], 'cytokines,': [444], 'factors,': [446], 'hormones': [447], '(1Griendling': [448], 'K.': [449, 490, 872, 1082, 1450, 2279, 2323, 2456, 2980, 3197, 3342, 3738, 4091, 4297, 4838, 4912, 5238, 5397], 'Sorescu': [450], 'D.': [451], 'Lassegue': [452], 'B.': [453, 1516, 4765], 'Ushio-Fukai': [454, 1052], 'M.': [455, 1032, 1056, 1060, 1072, 1076, 1424, 1428, 1440, 1444, 1517, 2297, 2301, 2313, 2317, 2430, 2434, 2446, 2450, 2831, 2835, 2954, 2958, 2970, 2974, 3171, 3175, 3187, 3191, 3316, 3320, 3332, 3336, 4020, 4065, 4069, 4081, 4085, 4271, 4275, 4287, 4291, 4599, 4603, 4703, 4709, 4936], 'Arterioscler.': [456, 655, 3155, 4947], 'Thromb.': [457, 656, 3156, 4948], 'Vasc.': [458, 657, 3157, 4949], 'Biol.': [459, 555, 658, 808, 834, 1086, 1454, 1534, 2327, 2460, 2984, 3134, 3158, 3201, 3233, 3346, 3746, 4095, 4301, 4427, 4453, 4711, 4771, 4846, 4920, 4950, 5018, 5053, 5147], '2000;': [460, 583, 626, 645, 659, 744, 2061, 3448, 4627], '20:': [461, 660], '2175-2183Crossref': [462], 'PubMed': [463, 502, 565, 586, 629, 648, 662, 747, 818, 844, 860, 885, 995, 1020, 1047, 1096, 1464, 1544, 1642, 1781, 1841, 2064, 2291, 2337, 2470, 2994, 3144, 3162, 3211, 3243, 3356, 3451, 3465, 3756, 3983, 4008, 4035, 4105, 4311, 4437, 4463, 4479, 4630, 4721, 4781, 4856, 4930, 4954, 5028, 5063, 5157, 5182, 5251, 5409], 'Scopus': [464, 503, 566, 587, 630, 649, 663, 748, 819, 845, 861, 886, 996, 1021, 1048, 1097, 1465, 1545, 1643, 1782, 1842, 2065, 2292, 2338, 2471, 2995, 3145, 3163, 3212, 3244, 3357, 3452, 3466, 3757, 3984, 4009, 4036, 4106, 4312, 4438, 4464, 4480, 4631, 4722, 4782, 4857, 4931, 4955, 5029, 5064, 5158, 5183, 5252, 5410], '(827)': [465], 'Google': [466, 505, 568, 589, 632, 651, 665, 750, 821, 847, 863, 888, 998, 1023, 1050, 1069, 1099, 1437, 1467, 1547, 1645, 1784, 1844, 2067, 2294, 2310, 2340, 2443, 2473, 2844, 2967, 2997, 3147, 3165, 3184, 3214, 3246, 3329, 3359, 3454, 3468, 3759, 3986, 4011, 4038, 4078, 4108, 4284, 4314, 4440, 4466, 4482, 4612, 4633, 4724, 4784, 4859, 4933, 4957, 5031, 5066, 5160, 5185, 5254, 5412], 'Scholar),': [467, 3360, 4315, 4634, 4860, 4958, 5161], 'mechanical': [469], 'forces': [470], '(2Pimentel': [471, 2260], 'D.R.': [472, 2261], 'Amin': [473, 2262], 'J.K.': [474, 1524, 2263, 3124, 3223], 'Xiao': [475, 2264], 'L.': [476, 1007, 2265, 3995, 4942], 'Miller': [477, 2266], 'T.': [478, 623, 643, 2059, 2267, 3445, 3744, 4619, 4623, 4699, 4844, 4918, 5391], 'Viereck': [479, 2268], 'J.': [480, 482, 486, 554, 742, 807, 833, 856, 1009, 1041, 1063, 1085, 1431, 1453, 1533, 1638, 1776, 1835, 2269, 2271, 2275, 2304, 2326, 2437, 2459, 2838, 2961, 2983, 3133, 3178, 3200, 3232, 3323, 3345, 3461, 3745, 3997, 4029, 4072, 4094, 4278, 4300, 4426, 4452, 4475, 4606, 4710, 4770, 4845, 4919, 5017, 5052, 5146, 5178, 5399], 'Oliver-Krasinski': [481, 2270], 'Baliga': [483, 2272], 'R.': [484, 2273, 5401], 'Wang': [485, 2274], 'Siwik': [487, 2276], 'D.A.': [488, 2277], 'Singh': [489, 2278], 'Pagano': [491, 2280], 'P.': [492, 738, 2281, 5137], 'Colucci': [493, 2282], 'W.S.': [494, 2283], 'Sawyer': [495, 2284], 'D.B.': [496, 2285], 'Circ.': [497, 990, 2286, 3978, 5404], 'Res.': [498, 991, 2287, 3979, 5405], '2001;': [499, 857, 992, 1044, 2288, 3980, 4032, 4476, 4951, 5179], '89:': [500, 2289], '453-460Crossref': [501, 2290], '(288)': [504, 2293], 'Scholar).': [506, 666, 751, 864, 1051, 1468, 1646, 1785, 1845, 2068, 2341, 2474, 2845, 2998, 3166, 3469, 4039, 4483, 4785, 5067, 5186, 5255, 5413], 'However,': [507, 865, 3911, 5068], 'molecular': [509, 676, 2184, 4114], 'mechanism': [510], 'ROS': [513, 595, 952, 1104, 2815, 3063, 3257, 3280, 3520, 4117, 4210, 4333, 4980, 5385], 'alter': [514], 'not': [518, 895, 1119, 1234, 2825, 2921, 3714, 3929, 4119, 4486, 4591, 4683, 4730, 4752, 4797, 4983, 5190, 5212, 5301], 'established.': [519], 'Reactive': [520], 'thiols': [521, 605, 616, 689, 1938], 'Cys': [523, 543, 915, 3651, 3657, 4401, 4517], 'residues': [524], 'select': [526], 'proteins': [527, 709, 2189, 2495, 2510, 5311, 5363, 5435], 'are': [528, 2420, 4337, 5509], 'among': [529], 'most': [531, 673, 683, 5510], 'sensitive': [532, 4646], 'sites': [533, 3622, 4374], 'be': [535, 592, 780, 1165, 2771, 2800, 2945, 3413, 3812, 4136, 4499, 4731, 5092, 5097, 5272, 5279, 5417, 5441], 'modified': [536, 593, 1398, 1475, 1759, 1799, 3642, 5310], 'ROS.': [538], 'For': [539], 'example': [540], 'phosphatases': [545], '(3Lee': [546], 'S.R.': [547, 551], 'Kwon': [548], 'K.S.': [549], 'Kim': [550], 'Rhee': [552], 'S.G.': [553], 'Chem.': [556, 809, 835, 1087, 1455, 1535, 2328, 2461, 2985, 3135, 3202, 3234, 3347, 3747, 4096, 4302, 4428, 4454, 4712, 4772, 4847, 4921, 5019, 5054, 5148], '1998;': [557, 1065, 1433, 1536, 2306, 2439, 2840, 2963, 3136, 3180, 3235, 3325, 4074, 4280, 4608], '273:': [558, 1066, 1434, 1537, 2307, 2440, 2841, 2964, 3137, 3181, 3236, 3326, 4075, 4281, 4609], '15366-15372Abstract': [559], 'Full': [560, 562, 813, 815, 839, 841, 1091, 1093, 1459, 1461, 1539, 1541, 2332, 2334, 2465, 2467, 2989, 2991, 3139, 3141, 3206, 3208, 3238, 3240, 3351, 3353, 3751, 3753, 4100, 4102, 4306, 4308, 4432, 4434, 4458, 4460, 4716, 4718, 4776, 4778, 4851, 4853, 4925, 4927, 5023, 5025, 5058, 5060, 5152, 5154], 'Text': [561, 563, 814, 816, 840, 842, 1092, 1094, 1460, 1462, 1540, 1542, 2333, 2335, 2466, 2468, 2990, 2992, 3140, 3142, 3207, 3209, 3239, 3241, 3352, 3354, 3752, 3754, 4101, 4103, 4307, 4309, 4433, 4435, 4459, 4461, 4717, 4719, 4777, 4779, 4852, 4854, 4926, 4928, 5024, 5026, 5059, 5061, 5153, 5155], 'PDF': [564, 817, 843, 1095, 1463, 1543, 2336, 2469, 2993, 3143, 3210, 3242, 3355, 3755, 4104, 4310, 4436, 4462, 4720, 4780, 4855, 4929, 5027, 5062, 5156], '(844)': [567], 'Scholar)': [569, 590, 889, 1100, 3215, 3247, 3760, 4725, 5032], 'kinase': [572, 1345, 3719, 3780, 4760, 4885, 5074], 'C': [573, 3381, 4761], '(4Ward': [574], 'N.E.': [575], 'Stewart': [576], 'J.R.': [577], 'Ioannides': [578], 'C.G.': [579], "O'Brian": [580], 'C.A.': [581], 'Biochemistry.': [582, 644, 2060], '39:': [584, 646, 2062], '10319-10329Crossref': [585], '(119)': [588], 'can': [591, 612, 779], 'change': [597, 897, 5213, 5323], 'their': [598, 4663], 'function.': [599], 'Oxidants': [600], 'react': [601, 613], 'with': [602, 614, 918, 1202, 1473, 1478, 1485, 1493, 1568, 1578, 1648, 1679, 1693, 1719, 1745, 1752, 1762, 1791, 1802, 1857, 1904, 1976, 1993, 1999, 2027, 2047, 2079, 2116, 2133, 2192, 2204, 2207, 2219, 2247, 2374, 2379, 2391, 2398, 2409, 2418, 2498, 2531, 2537, 2550, 2562, 2580, 2614, 2621, 2640, 2697, 2761, 2790, 2933, 3015, 3294, 3306, 3559, 4174, 4404, 4545, 4662, 4898, 5229, 5314, 5427, 5531, 5546], 'these': [603, 5517], 'form': [607, 618, 691], 'thiyl': [608], 'radicals': [609], 'subsequently': [611], 'other': [615, 1282], 'mixed': [619, 692, 2191, 3425, 5432], 'disulfide': [620], 'bonds': [621], '(5Finkel': [622, 3444], 'FEBS': [624, 3446], 'Lett.': [625, 3447], '476:': [627, 3449], '52-54Crossref': [628, 3450], '(492)': [631, 1022, 3453, 4010], 'Scholar,': [633, 652, 822, 848, 999, 1024, 1070, 1438, 2295, 2311, 2444, 2968, 3148, 3185, 3330, 3455, 3987, 4012, 4079, 4285, 4441, 4467, 4613, 4934], '6Sullivan': [634], 'D.M.': [635, 2051], 'Wehr': [636, 2052], 'N.B.': [637, 2053], 'Fergusson': [638, 2054], 'M.M.': [639, 2055], 'Levine': [640, 2056], 'R.L.': [641, 2057], 'Finkel': [642, 2058], '11121-11128Crossref': [647, 2063], '(195)': [650, 2066], '7Wolin': [653], 'M.S.': [654, 1040, 4028], '1430-1442Crossref': [661], '(412)': [664], 'In': [667, 1181, 1931, 3303, 4122, 5125, 5458], 'mammalian': [668], 'abundant': [674], 'low': [675, 2183], 'thiol,': [677, 763, 5264], 'result': [681, 5415], 'likely': [684], 'bind': [686], 'disulfides,': [693], 'process': [695, 960, 3411, 5232], 'termed': [696], 'S-glutathiolation.': [697], 'Many': [698], 'previous': [699, 2258, 3307, 4899, 5126], 'reports': [700, 928, 2259, 3094, 4041, 4787, 4900, 5188], 'have': [701, 925, 4998, 5333], 'demonstrated': [702], '(GSS-)': [705], 'isolated': [706, 2397], 'purified': [708, 1599, 4410], 'tissues': [714], 'exposed': [715], 'nonspecific': [717], 'oxidants': [719, 3945, 4046], 'such': [720, 970], 'diamide': [722, 919, 5163], 'H2O2.': [724], 'A': [725, 2545, 3877, 5201, 5366], 'regulatory': [727], 'for': [729, 1191, 1284, 1488, 1619, 1765, 1805, 1887, 1973, 2010, 2092, 2106, 2120, 2195, 2216, 2365, 2383, 2402, 2415, 2477, 2503, 2590, 2673, 2679, 2684, 3476, 3507, 3766, 4052, 4116, 4209, 4339, 4351, 4520, 4527, 4539, 4799, 5429, 5496], 'GSS-protein': [730, 3424], 'adducts': [731], 'has': [732, 765, 920, 3113, 4118, 4673, 5294], 'only': [733], 'been': [734, 766, 921, 926, 1730, 3114, 4120, 4674], 'rarely': [735], 'documented': [736], '(8Klatt': [737], 'Lamas': [739], 'S.': [740, 804, 880, 979, 1005, 3728, 3967, 3993, 4423, 4617, 4621, 4828, 4902, 4944, 5014, 5246], 'Eur.': [741], 'Biochem.': [743, 855, 1064, 1432, 1637, 2305, 2438, 2839, 2962, 3179, 3324, 3460, 4073, 4279, 4474, 4607, 5177], '267:': [745], '4928-4944Crossref': [746], '(658)': [749], 'The': [752, 1370, 1469, 1503, 1590, 1624, 1695, 1737, 1987, 2188, 2198, 2368, 2413, 2523, 2558, 2598, 2693, 2736, 3551, 3590, 3785, 4532], 'modulates': [756, 3720], 'diverse': [757], 'pathways,': [759], 'Cys118,': [764, 3626, 3807, 4378], 'identified': [767, 2658, 2700, 3624, 4134, 4173, 4376], 'GTP-binding': [770, 4395], 'region': [771], 'Ras.': [773, 910, 2015, 3420, 4220, 5365], 'Previous': [774, 3093, 4040], 'work': [775], 'shows': [776], 'S-nitrosated,': [781], 'an': [784, 1251, 1720, 3409, 3694, 3952, 4111, 4405, 4881, 5273, 5295], 'downstream': [791, 1732, 2940, 3275, 3764, 4167], '(9Lander': [793, 4412, 5003], 'H.M.': [794, 830, 4413, 4449, 5004, 5049], 'Hajjar': [795, 4414, 5005], 'D.P.': [796, 4415, 5006], 'Hempstead': [797, 831, 4416, 4450, 5007, 5050], 'B.L.': [798, 832, 4417, 4451, 5008, 5051], 'Mirza': [799, 4418, 5009], 'U.A.': [800, 4419, 5010], 'Chait': [801, 4420, 5011], 'B.T.': [802, 4421, 5012], 'Campbell': [803, 873, 4422, 5013, 5239], 'Quillam': [805, 4424, 5015], 'L.A.': [806, 1824, 4425, 5016], '1997;': [810, 4429, 4713, 4773, 5020], '272:': [811, 4430, 4714, 4774, 5021], '4323-4326Abstract': [812, 4431, 5022], '(448)': [820, 4439, 5030], '10Teng': [823, 4442], 'K.K.': [824, 1062, 1084, 1430, 1452, 2303, 2325, 2436, 2458, 2837, 2960, 2982, 3177, 3199, 3322, 3344, 4071, 4093, 4277, 4299, 4443, 4605, 4938, 5043], 'Esposito': [825, 4444, 5044], 'D.K.': [826, 4445, 5045], 'Schwartz': [827, 4446, 5046], 'G.D.': [828, 3734, 4447, 4615, 4834, 4908, 5047], 'Lander': [829, 4448, 5048], '1999;': [836, 1088, 1456, 1778, 2329, 2462, 2986, 3203, 3348, 3748, 4097, 4303, 4455, 4848, 4922, 5055], '274:': [837, 1089, 1457, 2330, 2463, 2987, 3204, 3349, 3749, 4098, 4304, 4456, 4849, 4923, 5056], '37315-37320Abstract': [838, 4457, 5057], '(46)': [846, 4465, 5065], '11Mallis': [849, 4468], 'R.J.': [850, 4469, 5172, 5393], 'Buss': [851, 4470, 5173], 'J.E.': [852, 1526, 3126, 3225, 4471, 5174], 'Thomas': [853, 4472, 5175], 'J.A.': [854, 4473, 5176], '355:': [858, 4477, 5180], '145-153Crossref': [859, 4478, 5181], '(149)': [862, 4481, 5184], 'Williams': [866], 'et': [867, 1053, 4696], 'al.': [868, 1054, 4697], '(12Williams': [869, 5235], 'J.G.': [870, 5236], 'Pappu': [871, 5237], 'S.L.': [874, 5240], 'Proc.': [875, 5241], 'Natl.': [876, 5242], 'Acad.': [877, 5243], 'Sci.': [878, 5244], 'U.': [879, 1001, 3989, 5245], 'A.': [881, 4707, 5247], '2003;': [882, 1639, 1838, 3159, 3462, 5248], '100:': [883, 5249], '6376-6381Crossref': [884, 5250], '(84)': [887, 5253], 'found': [890, 2645], 'S-nitrosation': [892, 4398, 5206, 5234, 5268, 5302], 'itself': [893, 906, 5210], 'may': [894, 962, 1164, 3412, 4729, 4788, 4821, 5091, 5120, 5211], 'directly': [896, 5322], 'conformation,': [899], 'thus': [900], 'questioning': [901], 'whether': [902, 3865, 4589], 'could': [905, 5271, 5344, 5416, 5440], 'explain': [907, 4791], 'activation': [908, 1114, 1171, 1178, 1228, 1237, 1254, 2934, 3045, 3083, 3269, 3478, 4126, 4155, 4248, 4343, 4593, 4735, 4748, 4801, 4824, 5041, 5084, 5383, 5508], 'S-Glutathiolation': [911], 'C-terminal': [914, 3631, 4383], 'reported,': [922], 'but': [923, 1118, 1233, 2920, 3532, 3713, 4756, 4802, 4968, 5218], 'there': [924], 'no': [927, 3914, 4970], 'regarding': [929, 3309], 'affecting': [935, 5358], 'activity.': [937], 'induces': [941], 'cell': [945, 1969, 5456], '(VSMC)': [946], 'hypertrophy,': [947], 'proliferation,': [948], 'migration': [950], 'via': [951, 1600, 4690, 5087, 5266], 'formation': [953, 1197, 2816, 2856, 2932, 3404, 3497, 3506, 3873, 3919, 3927, 4231, 4245, 4341, 4514, 4888, 4977, 5487], 'stimulation': [955], 'contribute': [963, 1129, 3855, 5121, 5519], 'variety': [966], 'diseases,': [969], 'hypertension,': [972], 'atherosclerosis,': [973], 'restenosis': [975], '(13Wang': [976, 3964], 'H.D.': [977, 3965], 'Xu': [978, 3966], 'Johns': [980, 3968], 'D.G.': [981, 1015, 3969, 4003], 'Du': [982, 3970], 'Y.': [983, 1080, 1448, 2321, 2454, 2978, 3195, 3340, 3742, 3971, 4089, 4295, 4701, 4842, 4916, 5387, 5389], 'Quinn': [984, 3972], 'M.T.': [985, 3973], 'Cayatte': [986, 3974], 'A.J.': [987, 3975], 'Cohen': [988, 3976], 'R.A.': [989, 3977], '88:': [993, 3981], '947-953Crossref': [994, 3982], '(311)': [997, 3985], '14Landmesser': [1000, 3988], 'Cai': [1002, 3990], 'H.': [1003, 1011, 3730, 3732, 3991, 3999, 4705, 4830, 4832, 4904, 4906], 'Dikalov': [1004, 3992], 'McCann': [1006, 3994], 'Hwang': [1008, 3996], 'Jo': [1010, 3998], 'Holland': [1012, 1035, 4000, 4023], 'S.M.': [1013, 1036, 4001, 4024], 'Harrison': [1014, 4002], 'Hypertension.': [1016, 4004], '2002;': [1017, 4005, 5149, 5406], '40:': [1018, 4006], '511-515Crossref': [1019, 4007], '15Barry-Lane': [1025, 4013], 'P.A.': [1026, 4014], 'Patterson': [1027, 4015], 'C.': [1028, 1830, 4016], 'van': [1029, 4017], 'der': [1030, 4018], 'Merwe': [1031, 4019], 'Hu': [1033, 4021], 'Z.': [1034, 4022], 'Yeh': [1037, 4025], 'E.T.H.': [1038, 4026], 'Runge': [1039, 4027], 'Clin.': [1042, 1836, 4030], 'Invest.': [1043, 1837, 4031], '108:': [1045, 4033], '1513-1522Crossref': [1046, 4034], '(427)': [1049, 4037], '(16Ushio-Fukai': [1055, 1423, 2429, 2830, 2953, 3170, 3315, 4064, 4270, 4598], 'Alexander': [1057, 1073, 1425, 1441, 2298, 2314, 2431, 2447, 2832, 2955, 2971, 3172, 3188, 3317, 3333, 4066, 4082, 4272, 4288, 4600, 4945], 'R.W.': [1058, 1074, 1426, 1442, 2299, 2315, 2432, 2448, 2833, 2956, 2972, 3173, 3189, 3318, 3334, 4067, 4083, 4273, 4289, 4601, 4946], 'Akers': [1059, 1075, 1427, 1443, 2300, 2316, 2433, 2449, 2834, 2957, 2973, 3174, 3190, 3319, 3335, 4068, 4084, 4274, 4290, 4602], 'Griendling': [1061, 1083, 1429, 1451, 2302, 2324, 2435, 2457, 2836, 2959, 2981, 3176, 3198, 3321, 3343, 4070, 4092, 4276, 4298, 4604, 4937], '15022-15029Scopus': [1067, 1435, 2308, 2441, 2842, 2965, 3182, 3327, 4076, 4282, 4610], '(585)': [1068, 1436, 2309, 2442, 2843, 2966, 3183, 3328, 4077, 4283, 4611], '17Ushio-Fukai': [1071, 1439, 2312, 2445, 2969, 3186, 3331, 4080, 4286], 'Yin': [1077, 1445, 2318, 2451, 2975, 3192, 3337, 4086, 4292], 'Q.': [1078, 1446, 2319, 2452, 2976, 3193, 3338, 4087, 4293], 'Fujio': [1079, 1447, 2320, 2453, 2977, 3194, 3339, 4088, 4294], 'Walsh': [1081, 1449, 2322, 2455, 2979, 3196, 3341, 4090, 4296], '22699-22704Abstract': [1090, 1458, 2331, 2464, 2988, 3205, 3350, 4099, 4305], '(499)': [1098, 1466, 2339, 2472, 2996, 3213, 3358, 4107, 4313], 'showed': [1101, 1123, 3095, 4745, 4814, 5369], 'AII-stimulated': [1103, 1186, 4979], 'Akt,': [1117, 1340, 2938, 4050], 'ERK.': [1120, 1180, 4873], 'They': [1121], 'also': [1122, 2885, 3273, 3542, 3788, 4253, 5105], 'ERK': [1127, 1236, 2922, 3298, 3537, 3715, 3768, 3859, 3893, 3904, 4592, 4641, 4689, 4734, 4800, 4823, 4894, 4962], 'pathways': [1128, 5095], 'synergistically': [1130], 'hypertrophy': [1134, 1163, 3829, 3957, 4060], 'showing': [1136, 4322], 'MEK': [1139], 'inhibitor,': [1140, 1145, 3069, 4886], 'PD98059,': [1141], 'SB203580,': [1146], 'each': [1147, 2124, 2361], 'blocked': [1148, 1158, 3890], '∼40%': [1149], 'response,': [1153], 'whereas': [1154], 'together': [1155, 5313], 'they': [1156, 5343], 'additively': [1157], 'response.': [1160], 'Therefore,': [1161, 3167, 3862, 4506, 4874, 4975, 5076], 'mediated': [1166, 3930, 4753], 'part': [1168], 'redox-insensitive': [1177], 'employed': [1185, 4369], 'VSMC': [1187, 1417, 1860, 2117, 2818, 2952, 3251, 3828], 'model': [1190], 'examining': [1192], 'relationship': [1194], 'between': [1195, 2783], 'adenovirus-mediated': [1203], 'genetic': [1204], 'modulation': [1205], '(GRX-1)': [1210], '(C118S': [1216, 3690], 'Ras).': [1217], 'Our': [1218], 'studies': [1219, 4813, 5332], 'indicate': [1220, 3802, 4042], 'oxidant-induced': [1222], 'mediates': [1227], 'Drugs': [1246], 'Antibodies—Sulfo-NHS': [1248], 'biotin': [1249, 2186], 'EZ-link': [1252], 'kit': [1255], 'were': [1256, 1267, 1286, 1306, 1318, 1347, 1390, 1410, 1418, 1471, 1498, 1550, 1588, 1617, 1701, 1743, 1795, 1861, 1899, 1989, 2129, 2190, 2200, 2370, 2483, 2496, 2511, 2632, 2657, 2676, 2726, 2759, 2788, 3592, 3605, 3623, 4375], 'obtained': [1257, 1268, 1287, 1293, 1298, 1319, 1330, 1348, 1357, 1368, 1378, 1391, 1411, 2425, 2727], 'Pierce.': [1259], 'PD-10': [1260, 2176, 2515], 'desalting': [1261], 'columns,': [1262], 'A-Sepharose,': [1264], 'streptavidin-Sepharose': [1266, 2193], 'Amer-sham': [1270], 'Biosciences.': [1271], 'Bradford': [1272, 1895], 'assay,': [1274], 'Bio-spin': [1275], '6': [1276], 'column,': [1277], 'polyvinylidene': [1278], 'difluoride': [1279], 'membrane,': [1280], 'reagents': [1283], 'immunoblotting': [1285, 2026, 2246, 2591], 'Bio-Rad.': [1289], 'Polymer': [1290], 'polyethylenimine': [1291, 1756], 'Aldrich.': [1295], 'AG1478': [1296, 3884, 3912, 4959], 'Calbiochem': [1300], '(San': [1301, 1361], 'Diego,': [1302, 1362], 'CA).': [1303, 1363, 1396], 'Other': [1304], 'chemicals': [1305], 'Sigma.': [1308], 'Epidermal': [1309], 'factor': [1311], '(EGF)': [1312], 'anti-Ras': [1314, 2028, 2249, 2539], 'antibody': [1315, 1328, 1355, 1366, 1376, 2029, 2250, 2540, 2555], '(clone': [1316], 'Ras10)': [1317], 'Upstate': [1321], 'Biochemical': [1322], '(Golden,': [1323], 'CO).': [1324], 'Rabbit': [1325], 'anti-mouse': [1326, 2552], 'IgG': [1327], 'Jackson': [1332], 'ImmunoResearch': [1333], '(West': [1334], 'Grove,': [1335], 'PA).': [1336], 'Anti-phosphorylated': [1337], 'total': [1339, 1968], 'p70S6': [1344, 3718, 3779], 'antibodies': [1346], 'Cell': [1350, 1414], 'Signaling': [1351, 3394], '(Beverly,': [1352], 'MA).': [1353], 'Anti-p47phox': [1354], 'Transduction': [1359], 'Laboratories': [1360], 'Anti-human': [1364], 'catalase': [1365, 1504, 3169, 3262, 3361, 4242], 'Binding': [1371], 'Site': [1372, 2650], '(Birmingham,': [1373], 'UK).': [1374], 'Anti-GRX': [1375], 'American': [1380], 'Diagnostica': [1381], 'Inc.': [1382], '(Greenwich,': [1383], 'CT).': [1384], 'cDNA': [1386, 1656], 'adenoviral': [1388, 1554, 1586, 1625, 1707, 1721, 3695], 'vector': [1389, 1556, 1565, 1626, 1662, 1665, 1708, 1722], 'Clontech': [1393], '(Palo': [1394], 'Alto,': [1395], "Dulbecco's": [1397, 1474, 1758, 1798], "Eagle's": [1399, 1476, 1760, 1800], 'medium,': [1400], '(FBS),': [1404], 'pENTRD/Topo': [1405, 1664], 'vector,': [1406, 3696], 'Gateway': [1408, 1726], 'cassette': [1409, 1727], 'Invitrogen.': [1413], 'Culture—Rat': [1415], 'prepared': [1419], 'reported': [1421, 1632, 1822, 2046, 4726], 'before': [1422, 1491, 1808], 'grown': [1472], 'medium': [1477, 1761, 1790, 1801], '10%': [1479, 1763, 2380], 'FBS': [1480, 1487, 1764, 1804], 'penicillin/streptomycin': [1482], 'quiescent': [1484, 1796], '0.1%': [1486, 1803, 2208], '36-48': [1489], 'h': [1490, 1767, 1807, 1975, 2094, 2353, 2508], 'treating': [1492], 'Virus': [1495], 'Preparation—Adenoviral': [1496], 'constructs': [1497], 'developed': [1499], 'previously': [1501, 1631, 1729, 1821, 2045, 2829, 2942, 4269], 'described.': [1502], '(ATCC)': [1505], '(DN-p47phox,': [1509], 'S303A/S304A': [1510], 'double': [1511, 1602], 'mutant,': [1512], 'gift': [1513], 'Dr.': [1515, 5532, 5538], 'Babior': [1518, 1531, 3131, 3230], '(18Inanami': [1519, 3119, 3218], 'O.': [1520, 3120, 3219], 'Johnson': [1521, 3121, 3220], 'J.L.': [1522, 3122, 3221], 'McAdara': [1523, 3123, 3222], 'Benna': [1525, 3125, 3224], 'Faust': [1527, 3127, 3226], 'L.R.': [1528, 3128, 3227], 'Newburger': [1529, 3129, 3228], 'P.E.': [1530, 3130, 3229], 'B.M.': [1532, 3132, 3231], '9539-9543Abstract': [1538, 3138, 3237], '(151)': [1546, 1644, 3146, 3245, 3467], 'Scholar))': [1548], 'cDNAs': [1549], 'subcloned': [1551, 1658], 'into': [1552, 1570, 1581, 1863, 1901, 2485, 3693], 'shuttle': [1555, 1564], '(pShuttle),': [1557], 'contains': [1559], 'cytomegalovirus': [1561, 1735], 'promoter.': [1562, 1736], 'co-transfected': [1567], 'pADEasy': [1569], 'Escherichia': [1571], 'coli,': [1572], 'resultant': [1574], 'cosmid': [1575], 'transfected': [1577, 1744], 'calcium': [1579], 'phosphate': [1580, 2135], 'HEK': [1582, 1595], '293': [1583, 1596], 'cells,': [1584, 5380], 'plaques': [1587], 'selected.': [1589], 'adenovirus': [1591, 1751], 'propagated': [1593], 'cesium': [1603], 'chloride': [1604, 3071], 'gradient.': [1605], 'Using': [1606], 'TCID50': [1608], 'method,': [1609], 'viral': [1611], 'titer': [1612], 'determined.': [1614], 'Similar': [1615, 3514], 'methods': [1616, 2042], 'creation': [1621], 'β-galactosidase.': [1623], 'express': [1628], 'GRX-1': [1629, 3386, 3481, 3488, 3524, 3540, 4149, 4557], '(19Song': [1633], 'J.J.': [1634, 3457], 'Lee': [1635, 3458], 'Y.J.': [1636, 3459], '373:': [1640, 3463], '845-853Crossref': [1641, 3464], 'Adenovirus': [1647], 'made': [1652, 1713, 2073], 'follows.': [1654], 'PCR.': [1667], 'Site-directed': [1668], 'mutagenesis': [1669], 'C118': [1671], 'introduced': [1673], '18': [1675], 'cycles': [1676], 'PCR': [1678], 'forward': [1680], 'primer': [1681, 1685], '5′-TGCTGGTGGGGAACAAGTCTGACCTGGCTGCACGC-3′': [1682], 'reverse': [1684], '5′-GCGTGCAGCCAGGTCAGACTTGTTCCCCACCAGCA-3′': [1686], 'followed': [1687, 2043, 2095, 2257], 'digestion': [1689], 'template': [1692], 'Dpn-1.': [1694], 'entire': [1696], 'sequence': [1698, 1704, 3614], 'confirmed': [1702, 1950, 2747, 4150, 4319], 'analysis.': [1705], 'Then': [1706], 'expressing': [1709], 'LR': [1715], 'clonase': [1716], 'reaction': [1717], '(Invitrogen)': [1718], 'had': [1728, 3913, 4969], 'inserted': [1731], 'at': [1739, 2089, 2103, 2386, 2729, 2860, 2900, 2905, 3025, 3088, 4131, 4198], 'about': [1740, 4999], '80%': [1741], 'confluency': [1742], '∼50': [1746], 'multiplicity': [1747], 'infection': [1749], '10': [1753, 2159, 2217, 2584, 3073], 'μm': [1754, 1875, 2151], 'polymer': [1755], '36': [1766, 1806], '(20Dodds': [1768], 'E.': [1769], 'Piper': [1770], 'T.A.': [1771], 'Murphy': [1772], 'S.J.': [1773], 'Dickson': [1774], 'G.': [1775, 3152], 'Neurochem.': [1777], '72:': [1779], '2105-2112Crossref': [1780], '(43)': [1783], 'After': [1786, 1915, 2235, 2342, 2351, 2389, 2506], 'washing': [1787, 2390], 'out': [1788], 'adenovirus,': [1792], 'start': [1810], 'experiments.': [1813, 2735], '2′,7′-Dichlorofluorscein': [1814], 'Fluorescence': [1815], 'Measurement': [1816], 'VSMC—The': [1818], 'method': [1819, 2256], '(21Dada': [1823], 'Chandel': [1825], 'N.S.': [1826], 'Ridge': [1827], 'K.M.': [1828], 'Pedemonte': [1829], 'Bertorello': [1831], 'A.M.': [1832], 'Sznajder': [1833], 'J.I.': [1834], '111:': [1839], '1057-1064Crossref': [1840], '(204)': [1843], 'Activity': [1847], 'Assay—Ras': [1848], 'GTP': [1849, 3010], 'binding': [1850, 3011], 'assessed': [1853, 3014, 3274], 'association': [1856], 'GST-Raf.': [1858], 'Cultured': [1859], 'scraped': [1862, 1900, 2484], 'lysis': [1864, 1902, 1918, 1995, 2205, 2486], 'buffer': [1865, 1903, 1996, 2001, 2136, 2140, 2206, 2224, 2226, 2238, 2487, 2565], '(50': [1866, 2566], 'mm': [1867, 1879, 1906, 2077, 2081, 2087, 2101, 2148, 2155, 2160, 2229], 'Tris-HCl,': [1868], 'pH': [1869, 2090, 2104, 2142], '7.4,': [1870, 2143], '0.25': [1871], 'm': [1872, 2400], 'sucrose,': [1873], '50': [1874, 1982, 2086, 2150], 'diethylenetriaminepentaacetic': [1876, 2152], 'acid,': [1877, 2153], '2': [1878, 2093, 2154], 'phenylmethylsulfonyl': [1880, 2156], 'fluoride)': [1881, 2157], 'centrifuged': [1883], '(10,000': [1884, 2500], '×': [1885, 2501], 'g': [1886, 2502], '15': [1888, 2504, 2861, 3026, 3089], 'min).': [1889, 2505], 'Protein': [1890, 2016], 'concentration': [1891], 'measured': [1893], 'assay.': [1896, 3019], 'Some': [1897], '20': [1905, 2228], 'DTT': [1907, 1956, 3037], 'test': [1909, 3471, 3677], 'dependence': [1912], 'equilibration': [1916], 'buffer,': [1919], 'GST-Raf': [1920, 1977, 3017], 'passed': [1922, 2173, 2512], 'over': [1923], 'Bio-6': [1925, 1962], 'spin': [1926], 'column': [1927, 2178, 2517], 'eliminate': [1929, 2180, 2519], 'DTT.': [1930], 'preliminary': [1932], 'studies,': [1933], 'measuring': [1935], 'free': [1937], 'albumin': [1942], '5,5′-dithiobis(2-nitrobenzoic': [1944], 'acid)': [1945], 'fluorescence': [1946, 2823], '(412': [1947], 'nm),': [1948], 'less': [1952, 4645], 'than': [1953], '1%': [1954, 2144], 'remained': [1957], 'after': [1958], 'passing': [1959], 'through': [1960, 2174, 2513, 3931], 'column.': [1963], 'Approximately': [1964, 2167, 2583, 3609], '700-1000': [1965], 'μg': [1966], 'incubated': [1972, 1998, 2215, 2364, 2535], '1': [1974, 2107, 2121, 2168, 2196, 2354, 2507], '(75': [1978], 'μg)': [1979], 'coupled': [1980], 'μl': [1983, 2221, 2570, 2585], 'immobilized': [1985], 'GSH-resin.': [1986], 'samples': [1988], 'washed': [1990, 2130, 2201, 2371], 'four': [1991, 2690, 2733], 'times': [1992, 2132, 2203, 2373], 'nonreducing': [1994, 2563, 2576], 'Laemmli': [2000, 2237, 2564], 'containing': [2002, 2158, 2239, 2488, 2628], '5%': [2003, 2240], 'β-mercaptoethanol': [2004], 'heated': [2006], '100': [2008], '°C': [2009], '5': [2011, 2897], 'min': [2012, 2218, 2385, 2862, 2907, 3090], 'dissociate': [2014], 'run': [2018], 'SDS-PAGE,': [2020, 3585], 'quantified': [2024], '(Upstate': [2030], 'Biochemical,': [2031], 'clone': [2032, 2252], 'Ras10).': [2033, 2253], 'Biotinylated': [2034, 2069, 2109], 'Ester': [2036], 'Detection': [2038], 'S-Glutathiolated': [2040], 'Ras—The': [2041], 'those': [2044], 'some': [2048], 'modifications': [2049], '(6Sullivan': [2050], 'ester': [2071, 2084, 2111], 'mixing': [2075], '25': [2076, 2080], 'sulfo-NHS-biotin': [2078], 'ethyl': [2083], 'NaHCO3': [2088], '8.5': [2091, 2105], 'addition': [2098], '125': [2100], 'NH4HCO3': [2102], 'h.': [2108, 2122, 2197, 2367], '(250': [2112, 2883], 'μm)': [2113, 2346, 2813, 2853, 2884], 'preincubated': [2115], 'culture': [2119], 'At': [2123], 'time': [2125, 3397], 'point': [2126], 'three': [2131, 2731, 3620, 4373], 'cold': [2134], 'lysed': [2138], '(Tris-HCl,': [2141], 'Nonidet': [2145], 'P-40,': [2146], '150': [2147], 'NaCl,': [2149], 'N-ethylmaleimide': [2161], 'block': [2163], 'further': [2164, 4318], 'reactions.': [2166], 'mg': [2169, 2526], 'Sephadex-G25': [2177, 2516], 'excess': [2182, 2520], 'weight': [2185], 'products.': [2187], 'beads': [2194, 2199], 'five': [2202, 2372], 'SDS,': [2209], 'final': [2212], 'precipitate': [2213], '40': [2220, 2569], 'elution': [2223], '(lysis': [2225], '+': [2227], 'DTT)': [2230], 'release': [2232, 3107], 'S-glutathiolated': [2233, 3419, 3813], 'proteins.': [2234], 'adding': [2236], 'β-mercaptoethanol,': [2241], 'monoclonal': [2248, 2538], '(UBI,': [2251], 'Leucine': [2254], 'Incorporation—The': [2255], '16Ushio-Fukai': [2296], 'quiescence,': [2343], '(0.1': [2345, 2812, 2852], 'added': [2348, 2359, 2549], 'VSMC.': [2350, 3485, 3700, 4505, 4694], '16': [2352], 'μCi/ml': [2355], '[3H]leucine': [2357, 2781, 3378], 'dish': [2362], '8': [2366], 'phosphate-buffered': [2375], 'saline': [2376], 'fixed': [2378], 'trichloroacetic': [2381], 'acid': [2382, 2490], '30': [2384, 2901, 3075, 3887], '4': [2387], '°C.': [2388], 'ice-cold': [2392], 'water': [2393], 'once,': [2394], '0.5': [2399], 'NaOH': [2401], '90': [2403], 'min,': [2404, 2898, 2902], 'radioactivity': [2406], 'counted': [2408], 'scintillation': [2411], 'counter.': [2412], 'values': [2414], 'treated': [2417], 'normalized': [2421], 'value': [2424], 'untreated': [2427, 2784], 'Purification': [2476], 'MALDI-TOF': [2478, 2635, 3595], 'Mass': [2479, 3561], 'Spectrometry': [2480], 'Analysis—The': [2481], 'iodoacetic': [2489, 2521], '(10': [2491], 'mm),': [2492], 'separated': [2497, 2574, 3583], 'centrifugation': [2499], 'acid.': [2522], 'lysate': [2524], '(2-3': [2525], 'protein)': [2528], 'prewashed': [2530], 'A-Sepharose': [2533], 'overnight': [2536], '(25': [2541], 'μg).': [2542, 2557], 'Thereafter,': [2543], '(≈100': [2546], 'μl)': [2547], 'rabbit': [2551], 'Ig': [2553], 'G': [2554], '(30': [2556], 'immunoprecipitate': [2559], 'released': [2561], 'μl),': [2567], 'sample': [2572, 2587], 'SDS-PAGE': [2577], 'stained': [2579], 'Coomassie': [2581], 'Blue.': [2582], 'identify': [2594, 3574, 4362], 'major': [2596, 4679, 4867], 'band.': [2597], 'band': [2601, 2757], 'cut': [2603], 'gel,': [2606], 'digested': [2610], 'gel': [2613], 'trypsin': [2615], '(Sequencing': [2616], 'grade;': [2617], 'Sigma)': [2618], 'dried': [2620], 'Speedvac': [2623], '(Savant,': [2624], 'Albertville,': [2625], 'MI).': [2626], 'GSS-Cys': [2627, 3554, 3575, 3602, 3621, 3641, 4364], 'peptides': [2629, 2656, 3591, 3643], 'spectrometry': [2637, 3638, 4176], 'analyzed': [2639, 2760, 2789, 3593, 3606], 'SWISS-PROT': [2642], 'data': [2643, 2694, 2703, 3801, 4330, 4637], 'base': [2644, 2704], 'Profound': [2648], 'Web': [2649], '(prowl.rockefeller.edu/cgibin/ProFound).': [2651], 'Reduced': [2652], 'Cys-': [2653], 'GSS-Cys-containing': [2655], 'basis': [2661], 'predicted': [2664], '(RSSG:': [2668], '+C10H15N3O6S).': [2669], 'Accepted': [2670], 'fit': [2671, 2695], 'parameters': [2672], 'peptide': [2674], '<100': [2677], 'ppm': [2678, 2683], 'monoisotopic': [2680], 'mass,': [2681, 2686], '<200': [2682], 'average': [2685], 'up': [2688], 'tryptic': [2691], 'miscleavages.': [2692], 'gi': [2706], '131873': [2707], 'sp': [2708], 'P20171': [2709], 'RASH': [2710], 'RAT': [2711], 'TRANSFORMING': [2712], 'PROTEIN': [2713], 'P21/H-RAS-1': [2714], '(C-H-RAS).': [2715], 'Data': [2716], 'Analysis—For': [2717], 'all': [2718], 'experiments': [2721], 'employing': [2722], 'immunoblots,': [2723], 'similar': [2724, 4323], 'least': [2730], 'separate': [2734, 5093], 'caused': [2743, 3498, 3830, 3874, 3896, 4061, 5197], 'densitometry': [2749], '(Molecular': [2750], 'Analyzer,': [2751], 'Hercules,': [2752], 'CA),': [2753], 'differences': [2755], 'densities': [2758], "Student's": [2762, 2791], 't': [2763, 2792], 'test.': [2764, 2793], 'p': [2765, 2794, 2863], '<': [2766, 2795, 2864], '0.05': [2767, 2796], 'considered': [2769, 2798], 'statistically': [2772, 2801], 'significant.': [2773, 2802], 'Differences': [2774], 'percentage': [2777], 'incorporation': [2782, 3376], 'AII-treated': [2786, 3581, 3647], 'Thiol-redox-sensitive': [2806], 'Activation': [2807, 3059], 'VSMC—AII': [2811], '2′,7′-dichlorofluorscein': [2822], '(data': [2824], 'shown)': [2826], 'shown': [2828, 2943, 3810, 4268, 4996, 5334], 'As': [2846], 'biotinylated': [2849], 'GSH,': [2850], '(3.6': [2857], '±': [2858], '0.4-fold': [2859], '0.05,': [2865], 'n': [2866], '=': [2867], '5;': [2868], 'Fig.': [2869, 2924, 3301], '1A).': [2870], 'concentration-dependent': [2878], 'manner': [2879], '(Fig.': [2880, 2888, 2908, 3038, 3091, 3270, 3379, 3399, 3512, 3538, 3549, 3716, 3783, 3798, 3909, 3922, 4192, 4234, 4249, 4572], '1B).': [2881, 2889], 'Increased': [2890], 'noted': [2893], 'early': [2895], 'peaked': [2899], '60': [2906], '1C).': [2909], 'Formation': [2910], 'preceded': [2913], '(Supplemental': [2923, 3300], '1).': [2925], 'temporal': [2928], 'correlation': [2929], 'two': [2939], 'involved': [2946, 3414, 3870, 4500, 4732], 'To': [2999, 3470, 4361], 'determine': [3000], 'importance': [3002, 3680, 4576], 'pull-down': [3018], '2-fold': [3024], 'min.': [3027], 'Importantly,': [3028], 'eliminated': [3035], '1D),': [3039], 'that,': [3041], 'like': [3042, 5338], 'formation,': [3044], 'dependent': [3051], 'thiol-redox': [3053], 'status.': [3054], 'Were': [3060], 'Mediated': [3061], 'Oxidase—A': [3066], '(DPI;': [3072], 'μm,': [3074, 3886], 'min)': [3076], '2A).': [3092], 'subunit,': [3102], 'triggers': [3106], 'H2O2,': [3111], 'implicated': [3115], '22Touyz': [3149], 'R.M.': [3150], 'Yao': [3151], 'Schiffrin': [3153], 'E.L.': [3154], '23:': [3160], '981-987Crossref': [3161], '(243)': [3164], 'either': [3168, 4237, 5267], 'DN-p47phox': [3217, 3264, 3287, 3363], 'overexpressed': [3249, 3483, 3698], 'decrease': [3253], 'contribution': [3255], 'Either': [3261], '2B).': [3271], 'We': [3272, 4484, 5526], 'events': [3277, 5518], 'affected': [3278, 5511], 'oxidase.': [3283], 'lesser': [3295], 'effects': [3296, 3517, 4324, 4664, 4878, 5317], '2).': [3302, 4250], 'addition,': [3304], 'compatible': [3305], 'inhibited': [3364, 3489, 3543, 3790, 3901, 4184, 4243, 4254, 4558, 4961], 'indicated': [3373, 3401], '2,': [3380], 'D).': [3383], 'Inhibits': [3387], 'Activation,': [3390], 'Redox-sensitive': [3392, 3675], 'Hypertrophic': [3393], 'AII—The': [3396], 'course': [3398], '1D)': [3400], 'reversible,': [3406], 'enzymatic': [3410], 'reduction': [3417], 'Thiol-disulfide': [3421], 'exchange': [3422], 'disulfides': [3426], 'specifically': [3428], 'regulated': [3429, 3438, 5443], 'enzyme': [3432, 5324], 'turn': [3436], 'reductase': [3443, 5376, 5424, 5449], '19Song': [3456], 'specificity': [3473, 4152, 4533], 'indicating': [3501, 3924], 'requirement': [3503], '3A).': [3513], 'inhibiting': [3519, 5381], 'production,': [3521], 'overexpression': [3522, 3541, 4178, 4240, 4547, 4648], 'markedly': [3525], 'without': [3534], 'effect': [3535, 3916, 4971], '3B).': [3539], '3C).': [3550], 'Identification': [3552], 'MALDITOF': [3560], 'Spectrometry—To': [3562], 'confirm': [3563], 'formed': [3567], 'endogenous': [3569], 'pools': [3571], 'sites,': [3576], 'immunopurified': [3579], 'trypsinized': [3587], 'gel.': [3589], 'spectrometry,': [3597, 3816, 4371, 4492], 'reduced': [3599], 'HS-Cys': [3600], '(Table': [3607], 'I).': [3608], '60%': [3610], 'coverage': [3611], 'H-Ras': [3616], 'achieved,': [3618], '(Cys80,': [3625, 4377], 'one': [3628, 4380], 'Cys181,': [3632, 4384], 'Cys184,': [3633, 3655, 4385], 'Cys186).Table': [3635], 'IMALDI-TOF': [3636], 'analysis': [3639], 'VSMCMeasured': [3648], 'massComputed': [3649], 'massErrorStartEndMetOIAASequenceppmReduced': [3650], '(-SH,': [3652], 'IAA-SH)Cys512886.42886.2804368+QVVIDGETCLLDILDTAGQEEYSAMRCys1182876.32876.3−4103128+VKDSDDVPMVLVGNKCDLAARTVESR2833.82834.2−161103128+VKDSDDVPMVLVGNKCDLAARTVESRCys181,': [3653], 'Cys1842872.22872.3−46162185+++EIRQHKLRLNPPDESGLGCMSCKCys181,': [3654], 'Cys1862876.32876.4−35165189++QHKLRLNPPDESGLGCMSCKCVLSS-Glutathiolated': [3656], '(GSS-Cys)GSS-Cys804303.04303.8−1169101+DQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKGSS-Cys1182707.32707.172102123RVKDSDDVPMVLVGNKCDLAARGSS-Cys181,': [3658], '-Cys184,': [3659], '-Cys1862386.82386.813170189KLNPPDESGLGCMSCKCVLS2708.52708.1143170189+KLNPPDESGLGCMSCKCVLS': [3661], 'Open': [3662], 'table': [3663], 'new': [3666], 'tab': [3667], 'Effects': [3668], 'Expression': [3672], 'Signaling—To': [3676], 'functional': [3679], 'S-glutathiolation,': [3682, 5276, 5445], 'mutated': [3687], 'serine': [3689], 'Ras),': [3691], 'incorporated': [3692], '4A).': [3717], '(23Eguchi': [3727, 4827, 4901], 'Iwasaki': [3729, 4829, 4903], 'Ueno': [3731, 4704, 4831, 4905], 'Frank': [3733, 4833, 4907], 'Motley': [3735, 4624, 4835, 4909], 'E.D.': [3736, 4625, 4836, 4910], 'Eguchi': [3737, 4616, 4837, 4911], 'Marumo': [3739, 4839, 4913], 'F.': [3740, 4840, 4914], 'Hirata': [3741, 4841, 4915], 'Inagami': [3743, 4622, 4843, 4917], '36843-36851Abstract': [3750, 4850, 4924], '(162)': [3758, 4858, 4932], 'target': [3765, 4115], 'both': [3767, 5112], 'Akt.': [3770, 3861, 4670, 4811, 4896], 'modestly': [3775], '4B).': [3784], 'significantly': [3789], '4C).': [3799], 'signaling,': [3824, 5342], 'leads': [3826], 'Is': [3834], 'Not': [3835], 'Downstream': [3836], 'EGF': [3838, 3866, 3881, 3932, 4819, 4863, 4871, 4882, 4987, 5088, 5115], 'Receptor': [3839], 'Transactivation': [3840], 'AII—EGF': [3842], 'receptor': [3843, 3867, 3882, 3933, 4820, 4883, 4988, 5089, 5116], 'transactivation': [3844, 3868, 4816, 5090, 5117], 'cascade': [3850], 'known': [3853], 'tested': [3864, 4544, 4876], 'selective': [3878], 'inhibitor': [3879], 'activity,': [3883, 5502], '(1': [3885], 'min),': [3888], 'completely': [3889], 'partially': [3900, 4960], '5A).': [3910], 'significant': [3915], '5B),': [3923], 'transactivation.': [3934, 4989], 'It': [3935, 4586], 'now': [3937], 'recognized': [3939], 'derived': [3946], 'play': [3951], 'important': [3953, 5476], 'pathogenesis': [3960], 'diseases': [3963], 'activate': [4047, 4218], 'accounting': [4051], 'component': [4055], 'Scholar);': [4109], 'however,': [4110], 'upstream': [4112], 'direct': [4113], 'identified.': [4121], 'step': [4139], 'involvement': [4164, 4536], 'activating': [4166], 'GSS-Cys118': [4171], 'strikingly': [4183], '6).': [4193], 'activated': [4197], 'plasma': [4200], 'membrane': [4201], 'where': [4202], 'hypothesize': [4204, 4511], 'it': [4205, 4213, 4507, 4681], 'situated': [4208], 'generated': [4211], 'attack': [4215], 'membrane-bound': [4219], 'hypothesis': [4222], 'supported': [4224], 'fact': [4227, 5421], '1B),': [4235], 'DPI': [4238], 'agents': [4252], 'overexpressing': [4326], 'DN-p47phox.': [4327], 'Collectively,': [4328], 'our': [4329, 4636, 4792], 'responsible': [4338, 4350, 4519, 5495], '(p38,': [4354], 'Akt)': [4355], 'site': [4365], 'Cys186).': [4387], 'Among': [4388], 'them,': [4389], 'located': [4392], 'region,': [4396], 'associated': [4403, 5227], 'did': [4485, 5189], 'detect': [4487], 'S-nitrosated': [4488], 'nor': [4493], 'nitric': [4495], 'oxide': [4496], 'thought': [4497], 'reasonable': [4509], 'GRX-1,': [4549, 4653], 'cytosolic': [4551], 'thioredoxin': [4555], 'superfamily.': [4556], '3),': [4573], 'emphasizing': [4574], 'GSS-adduct': [4579], 'mediating': [4583, 5478], 'controversial': [4588], '25Frank': [4614], 'Yamakawa': [4618], 'Tanaka': [4620], 'Endocrinology.': [4626], '141:': [4628], '3120-3126Crossref': [4629], '(103)': [4632], 'much': [4644], 'compared': [4661], 'Although': [4671, 5330], 'Ras/Raf/MEK1/ERK': [4672], 'widely': [4675], 'regarded': [4676], 'pathway,': [4680], 'clear': [4684], 'exclusively': [4687], 'activates': [4688, 4872], 'pathway': [4692, 4868], 'Takahashi': [4695], '(26Takahashi': [4698], 'Kawahara': [4700], 'Okuda': [4702], 'Takeshita': [4706], 'Yokoyama': [4708], '16018-16022Abstract': [4715], '(74)': [4723], 'rat': [4739], 'aortic': [4740], 'cells.': [4743], 'Others': [4744], 'Raf': [4747], 'rather': [4757, 5228], '(27Liao': [4762], 'D.F.': [4763], 'Monia': [4764], 'Dean': [4766], 'N.': [4767, 5141], 'Berk': [4768, 5402], 'B.C.': [4769, 5403], '6146-6150Abstract': [4775], '(208)': [4783], 'help': [4789], 'findings': [4793], 'required': [4798], 'Recent': [4812], 'mediate': [4822, 5037, 5451], 'receptor/Grb/mSOS/Ras': [4864], 'AG1478,': [4880], 'tyrosine': [4884], 'Compatible': [4897], '28Ushio-Fukai': [4935], 'Becker': [4939], 'P.L.': [4940], 'Hilenski': [4941], 'Halleran': [4943], '21:': [4952], '489-495Crossref': [4953], '(260)': [4956], 'formation.': [4974], 'apparently': [4981], 'consequence': [4985], 'Previously,': [4990], '75%': [5000], 'basal': [5001], 'preserved': [5034], 'ability': [5035], 'factor-dependent': [5039], 'mSOS-induced': [5040], '(10Teng': [5042], 'prevented': [5071], 'redox-dependent': [5072], 'PI3': [5073], 'GSS-Ras-mediated': [5077], 'mSOS-dependent': [5083], 'localized': [5098], 'different': [5100], 'compartments.': [5102], 'AG': [5103], '1478': [5104], 'reports,': [5127], 'ischemia-reperfusion': [5128], 'S-thiolation': [5130], 'labeling': [5131], 'heart': [5135], '(29Eaton': [5136], 'Byers': [5138], 'H.L.': [5139], 'Leeds': [5140], 'Ward': [5142], 'M.A.': [5143], 'Shattock': [5144], 'M.J.': [5145], '277:': [5150], '9806-9811Abstract': [5151], '(163)': [5159], 'GSS-Cys181': [5165], 'Cys184': [5167], 'recombinant': [5169, 5224], '(11Mallis': [5171], 'assess': [5191], 'changes': [5193], 'GSS': [5199], 'modification.': [5200], 'recent': [5202, 5367], 'report': [5203, 5368], 'structure': [5215], 'chemical': [5231], 'redox': [5259], 'cycling': [5260], 'possibly': [5265], 'sulfenilation': [5270], 'intermediate': [5274], 'would': [5278], 'favored': [5280], 'because': [5281], 'abundance': [5284], 'intracellular': [5286, 5349, 5485], 'GSH.': [5287], 'Because': [5288], 'glutamate': [5290], 'residue': [5291], 'extra': [5296], 'carboxyl': [5297], 'group,': [5298], '(but': [5300], 'sulfenilation)': [5304], 'adds': [5305], 'negative': [5307], 'charge': [5308], 'steric': [5316], 'tripeptide': [5320], 'might': [5321], 'analogous': [5326], 'phosphorylation.': [5329], 'many': [5331], 'antioxidants': [5337], 'N-acetylcysteine': [5339], 'inhibit': [5340], 'do': [5345], 'so': [5346], 'increasing': [5348], 'levels,': [5351], 'enhancing': [5352], 'key': [5361], 'fluid': [5371], 'shear': [5372], 'stress': [5373], 'up-regulated': [5374], 'endothelial': [5379], 'JNK': [5382], '(24Hojo': [5386], 'Saito': [5388], 'Tanimoto': [5390], 'Hoefen': [5392], 'Baines': [5394], 'C.P.': [5395], 'Yamamoto': [5396], 'Haendeler': [5398], 'Asmis': [5400], '91:': [5407], '712-718Crossref': [5408], '(69)': [5411], 'explained': [5418], 'couples': [5426], 'GRX': [5428], 'disulfide.': [5433], 'Thus,': [5434], 'various': [5437, 5455], 'cascades': [5439], 'reversibly': [5442], 'types.': [5457], 'summary,': [5459], 'clearly': [5462], 'shows,': [5463], '1)': [5464], 'ROS-mediated': [5467], 'actions': [5480], '2)': [5483], 'following': [5489], '3)': [5491], 'portion': [5498], 'Raf-binding': [5501], '4)': [5503], '5)': [5515], 'induced': [5523], 'appreciate': [5527], 'useful': [5529], 'discussions': [5530], 'Peter': [5533], 'Brecher': [5534], 'support': [5536], 'Tsuneo': [5539], 'Adachi.': [5540], 'Download': [5541], '.pdf': [5542], '(.23': [5543], 'MB)': [5544], 'Help': [5545], 'pdf': [5547], 'files': [5548]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1970203053', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 9}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 7}, {'year': 2016, 'cited_by_count': 8}, {'year': 2015, 'cited_by_count': 11}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 20}, {'year': 2012, 'cited_by_count': 19}], 'updated_date': '2025-01-07T18:05:00.471865', 'created_date': '2016-06-24'}