Publication Information

{'id': 'https://openalex.org/W1969837492', 'doi': 'https://doi.org/10.1097/00005373-199001000-00010', 'title': 'Systemic Lipid Peroxidation and Inflammation Induced by Thermal Injury Persists into the Post-resuscitation Period', 'display_name': 'Systemic Lipid Peroxidation and Inflammation Induced by Thermal Injury Persists into the Post-resuscitation Period', 'publication_year': 1990, 'publication_date': '1990-01-01', 'ids': {'openalex': 'https://openalex.org/W1969837492', 'doi': 'https://doi.org/10.1097/00005373-199001000-00010', 'mag': '1969837492', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2296069'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/00005373-199001000-00010', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2312674', 'display_name': 'Journal of Trauma and Acute Care Surgery', 'issn_l': '0022-5282', 'issn': ['0022-5282', '1529-8809'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5040203906', 'display_name': 'Robert H. Demling', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1283280774', 'display_name': "Brigham and Women's Hospital", 'ror': 'https://ror.org/04b6nzv94', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1283280774', 'https://openalex.org/I48633490']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'ROBERT H. DEMLING', 'raw_affiliation_strings': ["From the Longwood Area Trauma Center at Brigham and Women's. Beth Israel, and Boston Children's Hospitals, and Harvard Medical School, Boston."], 'affiliations': [{'raw_affiliation_string': "From the Longwood Area Trauma Center at Brigham and Women's. Beth Israel, and Boston Children's Hospitals, and Harvard Medical School, Boston.", 'institution_ids': ['https://openalex.org/I1283280774']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5050852083', 'display_name': 'Cheryl Lalonde', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1283280774', 'display_name': "Brigham and Women's Hospital", 'ror': 'https://ror.org/04b6nzv94', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1283280774', 'https://openalex.org/I48633490']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'CHERYL LALONDE', 'raw_affiliation_strings': ["From the Longwood Area Trauma Center at Brigham and Women's. Beth Israel, and Boston Children's Hospitals, and Harvard Medical School, Boston."], 'affiliations': [{'raw_affiliation_string': "From the Longwood Area Trauma Center at Brigham and Women's. Beth Israel, and Boston Children's Hospitals, and Harvard Medical School, Boston.", 'institution_ids': ['https://openalex.org/I1283280774']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.048, 'has_fulltext': False, 'cited_by_count': 100, 'citation_normalized_percentile': {'value': 0.961354, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '30', 'issue': '1', 'first_page': '69', 'last_page': '74'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11422', 'display_name': 'Burn Injury Management and Outcomes', 'score': 0.953, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11422', 'display_name': 'Burn Injury Management and Outcomes', 'score': 0.953, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/malondialdehyde', 'display_name': 'Malondialdehyde', 'score': 0.7553854}], 'concepts': [{'id': 'https://openalex.org/C2780829032', 'wikidata': 'https://www.wikidata.org/wiki/Q898539', 'display_name': 'Lipid peroxidation', 'level': 3, 'score': 0.85738456}, {'id': 'https://openalex.org/C2778401633', 'wikidata': 'https://www.wikidata.org/wiki/Q418661', 'display_name': 'Malondialdehyde', 'level': 3, 'score': 0.7553854}, {'id': 'https://openalex.org/C2776782833', 'wikidata': 'https://www.wikidata.org/wiki/Q3454235', 'display_name': 'Total body surface area', 'level': 2, 'score': 0.6572871}, {'id': 'https://openalex.org/C2993242423', 'wikidata': 'https://www.wikidata.org/wiki/Q170518', 'display_name': 'Burn injury', 'level': 2, 'score': 0.64128}, {'id': 'https://openalex.org/C2776252253', 'wikidata': 'https://www.wikidata.org/wiki/Q7663815', 'display_name': 'Systemic inflammation', 'level': 3, 'score': 0.60676426}, {'id': 'https://openalex.org/C2778165595', 'wikidata': 'https://www.wikidata.org/wiki/Q5491454', 'display_name': 'Resuscitation', 'level': 2, 'score': 0.5715667}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.5691877}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.54254705}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4333514}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.42981124}, {'id': 'https://openalex.org/C2777714996', 'wikidata': 'https://www.wikidata.org/wiki/Q7886', 'display_name': 'Lung', 'level': 2, 'score': 0.41174364}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.33706993}, {'id': 'https://openalex.org/C42407357', 'wikidata': 'https://www.wikidata.org/wiki/Q521', 'display_name': 'Physiology', 'level': 1, 'score': 0.33634254}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.304007}, {'id': 'https://openalex.org/C2776151105', 'wikidata': 'https://www.wikidata.org/wiki/Q898814', 'display_name': 'Oxidative stress', 'level': 2, 'score': 0.28163576}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.232066}], 'mesh': [{'descriptor_ui': 'D002056', 'descriptor_name': 'Burns', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015227', 'descriptor_name': 'Lipid Peroxidation', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D015121', 'descriptor_name': '6-Ketoprostaglandin F1 alpha', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015121', 'descriptor_name': '6-Ketoprostaglandin F1 alpha', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002056', 'descriptor_name': 'Burns', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002056', 'descriptor_name': 'Burns', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D002056', 'descriptor_name': 'Burns', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D015227', 'descriptor_name': 'Lipid Peroxidation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008168', 'descriptor_name': 'Lung', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008168', 'descriptor_name': 'Lung', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008315', 'descriptor_name': 'Malondialdehyde', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008315', 'descriptor_name': 'Malondialdehyde', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010101', 'descriptor_name': 'Oxygen Consumption', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011014', 'descriptor_name': 'Pneumonia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011014', 'descriptor_name': 'Pneumonia', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D011014', 'descriptor_name': 'Pneumonia', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D012756', 'descriptor_name': 'Sheep', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013929', 'descriptor_name': 'Thromboxane B2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013929', 'descriptor_name': 'Thromboxane B2', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/00005373-199001000-00010', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2312674', 'display_name': 'Journal of Trauma and Acute Care Surgery', 'issn_l': '0022-5282', 'issn': ['0022-5282', '1529-8809'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2296069', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.67}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4382128217', 'https://openalex.org/W4362507484', 'https://openalex.org/W4292940382', 'https://openalex.org/W2740612464', 'https://openalex.org/W2508691325', 'https://openalex.org/W2468294371', 'https://openalex.org/W2329248088', 'https://openalex.org/W2060853010', 'https://openalex.org/W2014071500', 'https://openalex.org/W1964671558'], 'abstract_inverted_index': {'We': [0, 196], 'determined': [1], 'the': [2, 6, 139, 165, 181, 216, 237, 244], 'time': [3, 221], 'course': [4], 'of': [5, 21, 85, 111, 150, 229, 239], 'oxidant-induced': [7], 'systemic': [8], 'lipid': [9, 35, 183, 202], 'peroxidation': [10, 184, 203], 'seen': [11, 248], 'after': [12, 73, 119, 126, 134, 206], 'burn': [13, 26, 120, 194, 207, 241], 'injury.': [14, 127], 'Twelve': [15], 'sheep': [16], 'were': [17, 37], 'given': [18], 'a': [19, 109, 240], '15%': [20], 'total': [22], 'body': [23], 'surface': [24], 'third-degree': [25], 'and': [27, 43, 48, 55, 67, 136, 161, 209, 227], 'monitored': [28, 38], 'for': [29, 138], '3': [30, 124], 'or': [31], '5': [32, 107], 'days.': [33], 'Circulating': [34], 'peroxides': [36], 'by': [39, 93], 'both': [40], 'malondialdehyde': [41], '(MDA)': [42], 'conjugated': [44], 'dienes': [45], '(CD).': [46], 'Lung': [47, 100], 'liver': [49, 230], 'tissue': [50], 'MDA': [51, 66, 144], 'was': [52, 69, 121, 131, 171, 189], 'also': [53, 91, 145, 172], 'measured': [54], 'compared': [56], 'to': [57, 104, 154, 179], 'controls.': [58], 'A': [59], 'significant': [60], 'but': [61], 'transient': [62], 'increase': [63], 'in': [64, 220, 254], 'circulating': [65], 'CD': [68], 'noted': [70], 'several': [71], 'hours': [72, 118, 160], 'burn.': [74], 'Venous': [75], 'plasma': [76], 'levels': [77], 'increased': [78, 92, 103, 123, 146, 163, 223], 'again': [79], '3-5': [80], 'days': [81, 125], 'postburn': [82], 'with': [83, 222, 236, 249], 'onset': [84], 'wound': [86], 'inflammation.': [87], 'Oxygen': [88], 'consumption,': [89], 'VO2,': [90, 224], '35': [94], '+/-': [95, 106, 113, 152, 156], '12%': [96], 'at': [97, 116, 158], 'this': [98, 211], 'time.': [99], 'MDA,': [101], 'which': [102], '64': [105], 'from': [108, 147], 'control': [110, 148], '45': [112], '4': [114], 'nMol/gm,': [115], '12': [117, 159], 'still': [122], 'Marked': [128], 'lung': [129, 225], 'inflammation': [130], 'present': [132], 'early': [133], 'injury': [135], 'persisted': [137], '5-day': [140, 166], 'study': [141], 'period.': [142, 167], 'Liver': [143], 'value': [149], '110': [151], '20': [153], '252': [155], '25': [157], 'remained': [162], 'over': [164], 'Serum': [168], 'alkaline': [169], 'phosphatase': [170], 'increased.': [173], 'Burn': [174], 'biopsies': [175], 'revealed': [176], 'no': [177], 'infection': [178], 'explain': [180, 243], 'ongoing': [182, 233], 'process,': [185], 'i.e.,': [186], 'bacterial': [187], 'content': [188], 'less': [190], 'than': [191], '10(5)': [192], 'organisms/gram': [193], 'tissue.': [195], 'conclude': [197], 'that': [198, 210], 'an': [199, 250], 'initial': [200], 'system': [201], 'occurs': [204], 'immediately': [205], 'injury,': [208], 'process': [212], 'continues': [213], 'well': [214], 'into': [215], 'post-resuscitation': [217], 'period,': [218], 'corresponding': [219], 'inflammation,': [226], 'evidence': [228], 'dysfunction.': [231], 'The': [232], 'oxidant': [234], 'changes': [235], 'presence': [238], 'may': [242], 'accentuated': [245], 'organ': [246], 'dysfunction': [247], 'additional': [251], 'septic': [252], 'insult': [253], 'burned': [255], 'patients.': [256]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1969837492', 'counts_by_year': [{'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-14T15:46:40.130373', 'created_date': '2016-06-24'}