Title: Bioactive Sesquiterpenoids and Diterpenoids from the Liverwort <i>Bazzania albifolia</i>
Abstract: Abstract One undescribed 6,7‐secofusicoccane‐type diterpene, albifolione ( 1 ), and one new aromadendrane‐type sesquiterpenoid ketone, methyl 2‐oxoaromadendra‐1(10),3‐dien‐12‐oate ( 2 ), along with four known compounds, δ ‐cuparenol ( 3 ), fusicoauritone ( 4 ), chiloscyphenols A and B ( 5 and 6 , resp.), were isolated from the liverwort Bazzania albifolia Horik. The structures and relative configurations of 1 and 2 were established unequivocally on the basis of spectroscopic data analysis. Preliminary bioassay revealed that compound 5 showed quite strong cytotoxicity against the human tumor cell line MCF‐7, with an IC 50 value of 5.6 μ M .
Publication Year: 2012
Publication Date: 2012-10-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 11
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