Publication Information

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3697, 3727, 3862, 4002, 4161, 4184, 4228], 'the': [8, 10, 22, 27, 67, 117, 121, 126, 228, 246, 251, 289, 291, 303, 308, 348, 398, 402, 407, 509, 527, 532, 693, 830, 942, 992, 1066, 1120, 1146, 1201, 1209, 1308, 1313, 1538, 1545, 1624, 1768, 1841, 1851, 2092, 2204, 2251, 2254, 2270, 2274, 2302, 2313, 2336, 2342, 2355, 2436, 2564, 2720, 2742, 2762, 2909, 2937, 2945, 3099, 3145, 3160, 3257, 3262, 3309, 3318, 3333, 3367, 3443, 3568, 3608, 3636, 3653, 3673, 3690, 3694, 3698, 3703, 3719, 3728, 3820, 3826, 3830, 3839, 3850, 3947, 3968, 4009, 4021, 4047, 4056, 4065, 4125, 4136, 4174, 4188, 4203, 4219, 4238, 4258, 4296, 4325], 'nucleus,': [9, 290, 1546], 'physiological': [11, 292, 608, 1539], 'significance': [12, 181, 293, 462], 'of': [13, 45, 56, 69, 103, 139, 160, 182, 205, 227, 248, 253, 294, 326, 337, 350, 384, 420, 441, 463, 486, 508, 529, 534, 669, 705, 843, 906, 1122, 1203, 1206, 1211, 1229, 1235, 1307, 1501, 1503, 1512, 1518, 1541, 1626, 1680, 1693, 1767, 2091, 2104, 2111, 2165, 2171, 2180, 2186, 2238, 2253, 2273, 2305, 2312, 2332, 2346, 2354, 2432, 2435, 2493, 2569, 2603, 2608, 2623, 2677, 2764, 2892, 2932, 3054, 3119, 3167, 3251, 3264, 3312, 3327, 3347, 3361, 3366, 3408, 3514, 3560, 3577, 3606, 3610, 3675, 3677, 3692, 3705, 3707, 3721, 3723, 3743, 3754, 3805, 3819, 3834, 3941, 3944, 3953, 3960, 3964, 3993, 4012, 4024, 4035, 4053, 4059, 4147, 4153, 4246, 4267, 4281], 'this': [14, 295, 1526, 4038, 4185], 'observation': [15, 296], 'is': [16, 297, 601, 1509, 1608, 1687, 1830, 3601, 3689, 3718, 3748, 3758, 4120, 4124, 4135, 4212], 'unknown.': [17, 298], 'As': [18, 299], 'shown': [19, 300, 3572], 'herein': [20, 301], 'for': [21, 302, 711, 900, 947, 1126, 1507, 2078, 2260, 2352, 2362, 2440, 2673, 2707, 2726, 2750, 2761, 2948, 2974, 2992, 3144, 3158, 3169, 3194, 3213, 3227, 3241, 3573, 3585, 3640, 3762, 3802, 3811, 3915, 3988, 4080, 4205, 4218], 'first': [23, 304], 'time,': [24, 305], 'ACBP': [25, 60, 73, 84, 113, 143, 156, 167, 183, 195, 221, 254, 258, 270, 306, 341, 354, 365, 394, 424, 437, 448, 464, 476, 502, 535, 539, 551, 683, 833, 890, 912, 1117, 1207, 1215, 1218, 1812, 1835, 1845, 1856, 1864, 2105, 2114, 2257, 2279, 2291, 2318, 2358, 2370, 2843, 3274, 3854, 4191, 4251, 4260, 4282, 4286], 'nucleus': [28, 68, 118, 309, 349, 399], 'physically': [29, 259, 310, 540], 'and': [30, 51, 65, 85, 97, 107, 114, 119, 144, 192, 213, 234, 250, 265, 311, 332, 346, 366, 378, 388, 395, 400, 425, 473, 494, 515, 531, 546, 690, 708, 981, 1094, 1137, 1165, 1240, 1417, 1421, 1424, 1621, 1634, 1703, 1707, 1709, 1722, 1813, 1821, 1854, 1867, 1955, 1989, 2032, 2065, 2087, 2096, 2106, 2113, 2124, 2131, 2168, 2193, 2256, 2282, 2292, 2319, 2339, 2359, 2366, 2371, 2495, 2555, 2584, 2611, 2663, 2680, 2693, 2724, 2754, 2769, 2787, 2844, 2867, 2885, 2906, 2942, 2954, 2980, 2995, 3002, 3019, 3049, 3062, 3080, 3084, 3150, 3153, 3174, 3200, 3276, 3295, 3336, 3350, 3355, 3370, 3395, 3432, 3457, 3464, 3482, 3494, 3502, 3522, 3527, 3531, 3536, 3542, 3567, 3588, 3647, 3661, 3739, 3769, 3780, 3788, 3815, 3832, 3855, 3871, 3927, 3981, 4055, 4133, 4179, 4192, 4225, 4231, 4241, 4248], 'functionally': [31, 312], 'interacted': [32, 260, 313, 541], 'with': [33, 75, 171, 185, 219, 261, 275, 314, 356, 452, 466, 500, 542, 556, 980, 1128, 1496, 1535, 1612, 1818, 1838, 1848, 2139, 2161, 2244, 2476, 2685, 2710, 2735, 2904, 2913, 2926, 2957, 2970, 2981, 3022, 3034, 3051, 3076, 3086, 3186, 3190, 3205, 3224, 3236, 3254, 3320, 3417, 3478, 3498, 3786, 3790, 4237, 4324], 'hepatocyte': [34, 315, 854, 858, 1314, 1616], 'nuclear': [35, 39, 127, 316, 320, 408, 575, 578, 855, 859, 1230, 1309, 1315, 1505, 1610, 3310], 'factor-4α': [36, 317], '(HNF-4α),': [37, 318], 'a': [38, 240, 319, 521, 602, 1609, 1676, 2140, 2147, 2162, 2169, 2245, 2264, 2552, 2617, 2858, 2876, 3052, 3087, 3322, 3436, 3488, 3507, 3574, 3602, 3684, 3713, 3741, 3752, 3843, 3999, 4207, 4291, 4331], 'binding': [40, 321, 581, 862, 2709, 3204], 'that': [42, 59, 323, 340, 832, 911, 1217, 1232, 1530, 1685, 1761, 1765, 2268, 2301, 3681, 3711, 3746, 3858, 3919, 3923, 3998, 4294], 'regulates': [43, 324], 'transcription': [44, 325, 1234, 1625], 'genes': [46, 327, 1236, 1629, 1694, 1750, 1771], 'involved': [47, 328, 893, 987, 1222, 1237, 1630, 1695], 'both': [49, 330, 1815, 2578, 3341], 'lipid': [50, 331, 696, 901, 1239, 1632, 1697, 1775, 1827], 'glucose': [52, 333, 1241], 'metabolism.': [53, 334, 845], 'Five': [54, 335], 'lines': [55, 336], 'evidence': [57, 338], 'showed': [58, 239, 339, 520], 'bound': [61, 342], 'HNF-4α': [62, 76, 86, 115, 145, 186, 262, 343, 357, 367, 396, 426, 467, 543, 1510, 1532, 1607, 1681, 1686, 1763, 1814, 1839, 1849, 1859, 2496, 3270, 3856, 4320], 'vitro': [64, 264, 345, 545, 909], 'intact': [70, 267, 351, 548], 'cells.': [71, 280, 352, 561, 3578, 4164], '(i)': [72, 353, 1834, 2328], 'interaction': [74, 184, 355, 465, 1127], 'elicited': [77, 358], 'significant': [78, 359, 1204], 'changes': [79, 360], 'secondary': [81, 362, 2188, 3239, 3304, 3342, 3351], 'structure.': [82, 363], '(ii)': [83, 364, 1844, 2340], 'were': [87, 164, 368, 445, 1751, 1772, 1959, 1966, 1992, 2011, 2035, 2070, 2090, 2097, 2128, 2137, 2151, 2197, 2297, 2308, 2323, 2375, 2498, 2542, 2665, 2683, 2744, 2759, 2793, 2840, 2854, 2902, 3013, 3047, 3072, 3096, 3111, 3124, 3142, 3184, 3221, 3259, 3282, 3301, 3314, 3353, 3459, 3496, 3517, 3534, 3593, 3773, 3823, 3859, 3912, 3929, 4084, 4235], 'coimmunoprecipitated': [88, 369], 'by': [89, 189, 211, 370, 470, 492, 1753, 2202, 2249, 2486, 2667, 2771, 2781, 2857, 2875, 2895, 3114, 3234, 3261, 3316, 3331, 3733, 3939, 4187, 4256], 'antibodies': [90, 371, 1983, 2003, 2439, 2686, 2835, 2847, 3226, 3240, 3253, 3922], 'to': [91, 125, 372, 406, 611, 686, 940, 984, 1774, 1825, 2155, 2267, 2327, 2563, 2576, 2613, 2719, 3058, 3066, 3374, 3442, 3652, 3777, 3848, 3935, 4076, 4112, 4171, 4195, 4214], 'each': [92, 373, 2175, 2261, 3348, 3803], 'protein.': [93, 374, 600, 888], '(iii)': [94, 375, 1855], 'Double': [95, 376], 'immunolabeling': [96, 377], 'laser': [98, 379, 875, 2487, 3439], 'scanning': [99, 380, 592, 876, 2488], 'confocal': [100, 381, 593, 877, 2489, 3147, 3863], 'microscopy': [101, 154, 382, 435, 878, 3148, 3864], '(LSCM)': [102, 383], 'rat': [104, 147, 200, 236, 385, 428, 481, 517, 2585, 2688, 3027, 3175, 3272, 4232, 4327], 'hepatoma': [105, 148, 201, 237, 386, 429, 482, 518, 1759, 2586, 2681, 3108, 3176, 3910, 4233], 'cells': [106, 110, 202, 238, 387, 391, 483, 519, 1213, 1760, 2587, 2662, 2682, 3095, 3109, 3123, 3177, 3220, 3258, 3313, 3562, 3911, 4234], 'transfected': [108, 389, 1212, 4236], 'COS-7': [109, 198, 390, 479, 3173], 'significantly': [111, 392], 'colocalized': [112, 393, 3861], 'within': [116, 157, 397, 438, 2616, 3838], 'perinuclear': [122, 403], 'region': [123, 404], 'close': [124, 405], 'membrane.': [128, 409], '(iv)': [129, 410], 'LSCM': [130, 226, 411, 507, 3394], 'fluorescence': [131, 412, 848, 2480, 3403, 4004, 4128, 4139, 4155], 'resonance': [132, 413, 571, 849, 2481], 'energy': [133, 414, 572, 850, 2482], 'transfer': [134, 415, 851, 1713, 2483, 2789], 'determined': [135, 416, 613, 2444, 2485, 2780, 3330, 3876], 'an': [136, 206, 417, 487, 1688, 2178, 2501, 2999, 3401, 3409, 3470, 3558, 4263, 4278, 4284], 'intermolecular': [137, 418, 3851, 4175], 'distance': [138, 419, 3852, 4176, 4204], '53': [140, 421], 'Å': [141, 159, 422, 440, 4217], 'between': [142, 245, 423, 526, 2278, 3612, 3737, 3853, 3867, 4177, 4190], 'cell': [149, 430, 2098, 3155], 'nuclei.': [150, 431], '(v)': [151, 432], 'Immunogold': [152, 433], 'electron': [153, 434, 3091], '43': [158, 439], 'HNF-4α.': [161, 442, 2478], 'These': [162, 443, 3045, 3792], 'interactions': [163, 444], 'specific': [165, 446], 'since': [166, 447], 'did': [168, 449, 2473], 'not': [169, 450, 1831, 2474, 3775], 'interact': [170, 451, 979, 1495], 'Sp1': [172, 453, 1990, 2695, 2767], 'or': [173, 199, 454, 480, 1225, 2547, 2572, 2874, 3031, 3037, 3340, 3614], 'glucocorticoid': [174, 455, 852, 1985], 'receptor': [175, 456, 853, 881, 883, 1310, 1316, 1396, 1611, 1986], 'these': [177, 458, 1504, 3668], 'assays.': [178, 194, 459, 475], 'The': [179, 460, 974, 1498, 2009, 2050, 2134, 2235, 2430, 2539, 2757, 2966, 3122, 3219, 3425, 3511, 3633, 3730, 3808, 4014, 4165, 4319], 'functional': [180, 461], 'was': [187, 468, 684, 1865, 1895, 1975, 2046, 2081, 2183, 2242, 2350, 2443, 2588, 2592, 2705, 2779, 2939, 2968, 3329, 3398, 3440, 3467, 3476, 3485, 3555, 3583, 3875, 3937, 3978, 3995, 4005, 4020, 4061, 4109, 4149, 4168, 4254, 4288], 'evidenced': [188, 469], 'mammalian': [190, 471, 2051, 2067, 4269], 'two-hybrid': [191, 472, 2068], 'transactivation': [193, 204, 277, 474, 485, 558], 'overexpression': [196, 477], 'enhanced': [203, 484], 'HNF-4α-dependent': [207, 488], 'luciferase': [208, 249, 489, 530, 1972, 2056, 2061, 3279], 'reporter': [209, 490, 2062, 4242], 'plasmid': [210, 491, 2058, 4293], '3.2-': [212, 493], '1.6-fold,': [214, 495], 'respectively.': [215, 496], 'In': [216, 256, 497, 537, 3306, 3667], 'contrast,': [217, 498], 'cotransfection': [218, 499], 'antisense': [220, 501, 4249, 4285], 'expression': [222, 271, 503, 552, 1857, 2052, 2057, 4240, 4252, 4270, 4321], 'vector': [223, 504, 2053, 4271, 4287, 4322], 'inhibited': [224, 505], 'transactivation.': [225, 506], 'individual': [229, 279, 510, 560, 2356], 'triple': [230, 511], 'fluorescent-labeled': [231, 512], '(HNF-4α,': [232, 513], 'ACBP,': [233, 514, 2192, 2689, 2765], 'luciferase)': [235, 516], 'high': [241, 522, 701, 3127], 'correlation': [242, 523, 3598], '(r2,': [243, 524], '0.936)': [244, 525], 'level': [247, 252, 272, 528, 533, 553, 1121], 'expression.': [255, 536], 'summary,': [257, 538], 'cells,': [268, 549], 'although': [269, 550], 'directly': [273, 554, 895, 1837, 1847], 'correlated': [274, 555], 'HNF-4α-mediated': [276, 557], 'Acyl-CoA-binding': [562], '1The': [565], 'abbreviations': [566], 'used': [567, 2077, 2089, 2324, 2351, 2836, 3143, 3283, 3302, 3584, 4170], 'are:': [568], 'ACBPacyl-CoA-binding': [569], 'proteinFRETfluorescence': [570], 'transferGRglucocorticoid': [573], 'receptorHNF-4αhepatocyte': [574], 'factor': [576, 579, 856, 860], '4αHNF-4α-LBDhepatocyte': [577], '4α-ligand': [580, 861], 'domain': [582, 863], '(amino': [583, 864, 2284], 'acids': [584, 865, 2285, 2307, 2334, 2348], '132-455)LCFAlong': [585], 'chain': [586, 589, 713, 868, 872], 'fatty': [587, 590, 714, 869, 873], 'acidLCFA-CoAlong': [588], 'acyl-CoALSCMlaser': [591], 'microscopyPPARperoxisome': [594], 'proliferator-activated': [595, 880, 1419], 'receptorTRthyroid': [596], 'receptorFITCfluorescein': [597], 'isothiocyanateL-FABPliver-fatty': [598], 'acid-binding': [599, 887, 1719], 'ubiquitous': [603], 'intracellular': [604, 695, 948, 1138], 'lipid-binding': [605], 'whose': [607], 'function': [609], 'remains': [610], 'be': [612, 687, 892, 1221, 4215], '(reviewed': [614, 950, 1148], 'Refs.': [616, 1150], '1Gossett': [617], 'R.E.': [618, 718, 1013, 2404], 'Frolov': [619, 719], 'A.A.': [620, 720, 758], 'Roths': [621, 721], 'J.B.': [622, 722], 'Behnke': [623, 723], 'W.D.': [624, 724], 'Kier': [625, 663, 725, 789, 929, 1024, 1077, 1344, 1557, 1883, 1925, 2392, 2415, 2805], 'A.B.': [626, 664, 726, 790, 930, 1025, 1078, 1345, 1558, 1884, 1926, 2393, 2416, 2806], 'Schroeder': [627, 661, 727, 759, 787, 927, 999, 1026, 1075, 1342, 1374, 1555, 1587, 1881, 1923, 2390, 2417, 2803], 'F.': [628, 662, 728, 760, 788, 928, 1000, 1027, 1076, 1343, 1375, 1556, 1588, 1882, 1924, 2391, 2418, 2511, 2804, 3881, 4090], 'Lipids.': [629, 729], '1996;': [630, 730, 749, 1645], '31:': [631, 731], '895-918Crossref': [632, 732], 'PubMed': [633, 656, 733, 752, 772, 795, 823, 935, 971, 1007, 1034, 1057, 1111, 1160, 1192, 1272, 1302, 1331, 1357, 1389, 1412, 1463, 1490, 1570, 1602, 1648, 1670, 1740, 1806, 1889, 1912, 1938, 2215, 2230, 2398, 2425, 2523, 2534, 2656, 2818, 2829, 3389, 3628, 3893, 3904, 4102, 4314], 'Scopus': [634, 734, 753, 773, 796, 824, 936, 1008, 1035, 1058, 1090, 1112, 1161, 1193, 1332, 1358, 1390, 1413, 1464, 1491, 1571, 1603, 1649, 1671, 1741, 1807, 1890, 1913, 1939, 2216, 2231, 2399, 2426, 2524, 2535, 2657, 2819, 2830, 3390, 3629, 3894, 3905, 4103, 4315], '(114)': [635, 735], 'Google': [636, 657, 736, 755, 775, 798, 826, 938, 972, 1010, 1037, 1060, 1092, 1114, 1163, 1195, 1273, 1303, 1334, 1360, 1392, 1415, 1466, 1493, 1573, 1605, 1651, 1673, 1743, 1809, 1892, 1915, 1941, 2218, 2233, 2401, 2428, 2526, 2537, 2659, 2821, 2832, 3392, 3631, 3896, 3907, 4105, 4317], 'Scholar,': [637, 658, 737, 756, 776, 799, 1011, 1274, 1335, 1361, 1467, 1574, 1652, 1916, 2219, 2402, 2527, 2822, 3897], '2Knudsen': [638, 953], 'J.': [639, 747, 761, 817, 819, 954, 1023, 1051, 1053, 1079, 1105, 1107, 1154, 1156, 1181, 1185, 1254, 1261, 1291, 1322, 1326, 1341, 1346, 1377, 1378, 1406, 1447, 1452, 1477, 1554, 1559, 1590, 1591, 1795, 1903, 1907, 1922, 1927, 2414, 2449, 2519, 2645, 2802, 2807, 3383, 3622, 3889, 4098], 'Jensen': [640, 955, 1176], 'M.V.': [641, 956], 'Hansen': [642, 957, 1172], 'J.K.': [643, 803, 958, 1173], 'Faergeman': [644, 814, 959, 1046, 1100, 1174], 'N.J.': [645, 739, 815, 960, 1047, 1101, 1152, 1175], 'Neergard': [646, 961, 1168], 'T.': [647, 962, 1256, 1276, 1445, 1778, 1788, 2453], 'Gaigg': [648, 963], 'B.': [649, 964, 1167, 1369, 1582], 'Mol.': [650, 965, 1186, 1734], 'Cell.': [651, 966, 1188, 1407, 1735], 'Biochem.': [652, 818, 967, 1029, 1052, 1106, 1155, 1408, 2226, 2420], '1999;': [653, 968], '192:': [654, 969], '95-103Crossref': [655, 970], '3Chao': [659], 'H.': [660, 778, 918, 1070, 1784, 1794, 1872, 2381], 'Creighton': [665], 'T.E.': [666], 'Wiley': [667, 673], 'Encyclopedia': [668], 'Molecular': [670, 2037, 2454], 'Medicine.': [671], 'John': [672], '&': [674], 'Sons,': [675], 'Inc.,': [676], 'New': [677, 3414], 'York2002:': [678], '44-47Google': [679], 'Scholar).': [680, 827, 973, 1115, 1196, 1304, 1606, 1674, 1744, 1810, 1893, 1942, 2234, 2429, 2470, 2538, 2660, 2833, 3393, 3632, 3908, 4106, 4318], 'Until': [681], 'recently,': [682], 'thought': [685], 'primarily': [688], 'cytosolic': [689, 975], 'unique': [691], 'among': [692], 'soluble': [694, 943], 'proteins': [697, 1140, 1231, 2338, 2579, 2853], 'exhibiting': [699], 'very': [700, 3074], 'affinity': [702], '(Kd': [703, 1511, 1517], 'values': [704, 3590, 3736], '0.5-10': [706], 'nm)': [707, 1514, 1520, 3012, 3434], 'exclusive': [709], 'specificity': [710, 2431], 'long': [712, 867, 871], 'acyl-CoAs': [715], '(LCFA-CoAs)': [716], '(1Gossett': [717], '4Faergeman': [738], 'Sigurskjold': [740], 'B.W.': [741], 'Kragelund': [742, 810], 'B.B.': [743, 811], 'Andersen': [744, 1178], 'K.V.': [745], 'Knudsen': [746, 816, 1022, 1050, 1104, 1153, 1184, 1446, 1476, 2413], 'Biochemistry.': [748, 791, 931, 1885, 2211, 2394], '35:': [750], '14118-14126Crossref': [751], '(123)': [754], '5Frolov': [757], 'Biol.': [762, 1187, 1347, 1379, 1453, 1560, 1592, 1736, 1796, 1928, 2646, 2808, 3385], 'Chem.': [763, 1348, 1380, 1454, 1561, 1593, 1797, 1929, 2647, 2809], '1998;': [764, 1031, 1328, 1909, 2422, 2520, 2648, 3890, 4099], '273:': [765, 2649], '11049-11055Abstract': [766], 'Full': [767, 769, 1085, 1087, 1267, 1269, 1297, 1299, 1352, 1354, 1384, 1386, 1458, 1460, 1565, 1567, 1597, 1599, 1801, 1803, 1933, 1935, 2651, 2653, 2813, 2815], 'Text': [768, 770, 1086, 1088, 1268, 1270, 1298, 1300, 1353, 1355, 1385, 1387, 1459, 1461, 1566, 1568, 1598, 1600, 1802, 1804, 1934, 1936, 2652, 2654, 2814, 2816], 'PDF': [771, 1089, 1271, 1301, 1356, 1388, 1462, 1569, 1601, 1805, 1937, 2655, 2817], '(53)': [774], '6Chao': [777], 'Martin': [779, 919, 1873, 2382], 'G.': [780, 920, 1729, 1874, 2383], 'Russell': [781, 785, 921, 925, 1020, 1875, 1879, 2384, 2388, 2411], 'W.K.': [782, 922, 1876, 2385], 'Waghela': [783, 923, 1877, 2386], 'S.D.': [784, 924, 1878, 2387], 'D.H.': [786, 926, 1021, 1880, 2389, 2412], '2002;': [792, 820, 932, 1082, 1349, 1487, 1562, 1798, 1886, 1930, 2395, 2810], '41:': [793, 933, 1265, 1295, 1887, 2396], '10540-10553Crossref': [794, 934, 1888, 2397], '(43)': [797, 937, 1891, 2400], '7Wadum': [800], 'M.C.T.': [801], 'Villadsen': [802], 'Feddersen': [804], 'S.': [805, 1248, 1286, 1290, 1403, 1449, 1479], 'Moller': [806], 'R.S.': [807], 'Neergaard': [808], 'T.B.F.': [809], 'Hojrup': [812], 'P.': [813], '365:': [821], '165-172Crossref': [822], '(18)': [825], 'Based': [828], 'on': [829, 1131, 2790, 3015, 3400, 3557, 3596], 'fact': [831], 'exclusively': [834], 'binds': [835, 1533], 'LCFA-CoAs,': [836], 'it': [837, 1528, 1829], 'may': [838, 891, 1118, 1219], 'participate': [839], 'several': [841], 'aspects': [842], 'LCFA-CoA': [844, 944, 983, 1124], '4α': [857, 1317], '132-455)': [866], 'acid': [870, 1040, 2973], 'acyl-CoA': [874], 'peroxisome': [879, 1418], 'thyroid': [882, 1394], 'fluorescein': [884], 'isothiocyanate': [885], 'liver-fatty': [886, 1718], 'First,': [889], 'presenting': [896], 'LCFACoAs': [897], 'as': [898, 1869, 1897, 2101, 2349, 2377, 2445, 2507, 2774, 2795, 2849, 3284, 3303, 3842, 3877, 3914, 3971, 4087, 4301], 'substrates': [899, 2888], 'metabolic': [902, 1132], 'enzymes.': [903], 'A': [904, 1745, 2456, 4244], 'variety': [905], 'studies': [907], 'suggest': [910, 1216], 'extracts': [913], 'LCFA-CoAs': [914, 1508, 1534, 1817], 'from': [915, 1961, 1968, 1976, 1994, 2036, 2047, 2071, 2083, 2153, 2199, 2335, 2505, 2559, 2580, 3098, 3435, 3563, 3825, 3933, 4050, 4074, 4151, 4273], 'membranes': [916, 2792], '(6Chao': [917, 1871, 2380], 'Scholar)': [939, 1494], 'increase': [941, 4157], 'pool': [945], 'available': [946, 1125, 2095], 'transport': [949, 1633], 'Ref.': [952], 'ACBP·LCFA-CoA': [976], 'complexes': [977], 'then': [978, 2543, 2955, 2996, 3222], 'present': [982], 'acyltransferase': [985], 'enzymes': [986, 1133], 'phospholipid': [989], 'synthesis': [990, 1041, 1064], 'endoplasmic': [993, 1067], 'reticulum': [994, 1068], '(8Jolly': [995], 'C.A.': [996, 1017, 2408], 'Wilton': [997], 'D.A.': [998, 1284], 'Biochim.': [1001], 'Biophys.': [1002, 1030, 2421], 'Acta.': [1003], '2000;': [1004, 1264, 1294], '1483:': [1005], '185-197Crossref': [1006], '(64)': [1009], '9Gossett': [1012, 2403], 'Edmondson': [1014, 2405], 'R.D.': [1015, 2406], 'Jolly': [1016, 2407], 'Cho': [1018, 2409], 'T.H.': [1019, 2410], 'Arch.': [1028, 2419], '350:': [1032, 2423], '201-213Crossref': [1033, 2424], '(38)': [1036, 2427], 'Scholar),': [1038, 1061, 1093, 1393, 1416], 'lysophosphatidic': [1039], 'mitochondria': [1043, 1097], '(10Rasmussen': [1044, 1098], 'J.T.': [1045, 1099], 'Kristiansen': [1048, 1102, 1257, 1287, 1450, 1480], 'K.': [1049, 1103, 1183, 1258, 1288, 1451, 1481, 1792], '1994;': [1054, 1108], '299:': [1055, 1109], '165-170Crossref': [1056, 1110], '(171)': [1059, 1113], 'cholesteryl': [1062], 'ester': [1063], '(11Chao': [1069], 'Zhou': [1071], 'M.': [1072, 1244, 1278, 1365, 1427, 1439, 1578, 1639, 1780, 1786], 'McIntosh': [1073], 'A.': [1074, 1246, 1367, 1405, 1580, 2640, 3378], 'Lipid': [1080, 1262, 1292], 'Res.': [1081, 1263, 1293], '44:': [1083], '72-83Abstract': [1084], '(57)': [1091], 'oxidation': [1095], 'Second,': [1116], 'control': [1119], 'unbound': [1123, 3252], 'regulatory': [1129], 'sites': [1130], '(e.g.': [1134, 1141, 3163], 'acetyl-CoA': [1135], 'carboxylase)': [1136], 'signaling': [1139], 'kinase': [1143], 'C)': [1144], 'cytosol': [1147], '12Faergeman': [1151], '1997;': [1157, 3386], '323:': [1158], '1-12Crossref': [1159], '(586)': [1162], 'Scholar': [1164], '13Gaigg': [1166], 'T.B.': [1169, 1252], 'Schneiter': [1170], 'R.': [1171, 1320, 1339, 1363, 1552, 1576, 1901, 1920, 2800], 'N.A.': [1177], 'J.R.': [1179], 'Friis': [1180], 'Sandhoff': [1182], '2001;': [1189, 1455, 1737, 2531, 3901], '12:': [1190], '1147-1160Crossref': [1191], '(120)': [1194], 'Third,': [1197], 'recent': [1198], 'data': [1199], 'demonstrating': [1200], 'presence': [1202, 2763], 'amounts': [1205], 'nuclei': [1210], 'overexpressing': [1214], 'also': [1220, 3682, 3784], 'direct': [1224], 'ligand': [1226], '(LCFA-CoA)-dependent': [1227], 'regulation': [1228], 'activate': [1233], 'metabolism': [1242, 1635, 1776], '(14Elholm': [1243], 'Garras': [1245], 'Neve': [1247], 'Tarnehave': [1249], 'D.': [1250, 1435, 1637, 3380], 'Lund': [1251], 'Skorve': [1253], 'Flatmark': [1255, 1444], 'Berge': [1259, 1442], 'R.K.': [1260, 1443], '538-545Abstract': [1266], '15Hellendie': [1275], 'Antonius': [1277], 'Sorensen': [1279], 'R.V.': [1280], 'Hertzel': [1281], 'A.V.': [1282], 'Bernlohr': [1283], 'Kolvraa': [1285], 'Mandrup': [1289, 1448, 1478], '1740-1751Abstract': [1296], 'Several': [1305, 3344], 'members': [1306], 'superfamily': [1311], 'including': [1312, 1699], '(HNF-4α)': [1318], '(16Hertz': [1319, 1900], 'Magenheim': [1321, 1902], 'Berman': [1323, 1370, 1583, 1904], 'I.': [1324, 1371, 1429, 1437, 1473, 1584, 1641, 1905], 'Bar-Tana': [1325, 1340, 1376, 1553, 1589, 1906, 1921, 2801], 'Nature.': [1327, 1666, 1908, 2825], '392:': [1329, 1910], '512-516Crossref': [1330, 1911], '(453)': [1333, 1914], '17Petrescu': [1336, 1917], 'A.D.': [1337, 1550, 1918, 2798], 'Hertz': [1338, 1551, 1919, 2799], '277:': [1350, 1563, 1799, 1931, 2811], '23988-23999Abstract': [1351, 1564, 1932, 2812], '(72)': [1359, 1572, 1808, 1940, 2820], '18Hertz': [1362, 1575], 'Ben-Naim': [1364, 1577], 'Petrescu': [1366, 1579], 'Kalderon': [1368, 1581], 'Eldad': [1372, 1585], 'N.': [1373, 1401, 1483, 1586, 1790], '2003;': [1381, 1594], '278:': [1382, 1595], '22578-22585Abstract': [1383, 1596], '(28)': [1391, 1604], 'hormone': [1395], '(TR)': [1397], '(19Li': [1398], 'Q.': [1399], 'Yamamoto': [1400], 'Morisawa': [1402], 'Inoue': [1404], '1993;': [1409, 3625], '51:': [1410], '458-464Crossref': [1411], '(23)': [1414], 'receptor-α': [1420], '-δ': [1422], '(PPAR-α': [1423], '-δ)': [1425], '(20Elholm': [1426], 'Dam': [1428], 'Jorgenesen': [1430], 'C.': [1431, 1469], 'Krogsdam': [1432, 1470], 'A.-M.': [1433, 1471], 'Holst': [1434], 'Kratchamarova': [1436, 1472], 'Gottlicher': [1438], 'Gustafsson': [1440], 'J.A.': [1441, 3621], '276:': [1456], '21410-21416Abstract': [1457], '(42)': [1465], '21Jorgensen': [1468], 'Willson': [1474], 'T.M.': [1475, 2517, 3887, 4096], 'Ann.': [1482], 'Y.': [1484, 1782], 'Acad.': [1485], 'Sci.': [1486], '967:': [1488], '431-439Crossref': [1489], '(16)': [1492], 'LCFA-CoAs.': [1497], 'relative': [1499], 'order': [1500, 2326, 3847], 'affinities': [1502, 1536, 1820], 'receptors': [1506], '1.5-4': [1513], '>>': [1515, 1521], 'TR': [1516], '120': [1519], 'PPARα': [1522], '(displaces': [1523], 'Wy14643).': [1524], 'On': [1525], 'basis,': [1527], 'appears': [1529], 'only': [1531, 3776, 3920], 'range': [1540], 'LCFACoA': [1542], 'levels': [1543], '<10': [1547], 'nm': [1548, 2157, 3480, 3500, 3987], '(17Petrescu': [1549, 2797], 'major': [1613], 'roles': [1614], 'differentiation': [1617], 'during': [1618], 'liver': [1619, 2582, 2591, 2609, 2679, 2938], 'development': [1620], 'regulating': [1623], 'numerous': [1627], 'target': [1628], '(22Kardassis': [1636], 'Laccotripe': [1638], 'Talianidis': [1640], 'Zannis': [1642], 'V.': [1643], 'Hypertension.': [1644], '27:': [1646], '980-1008Crossref': [1647], '(34)': [1650], '23Kuo': [1653], 'C.J.': [1654], 'Conley': [1655], 'P.B.': [1656], 'Chen': [1657], 'L.': [1658], 'Sladek': [1659], 'F.M.': [1660], 'Darnell': [1661], 'Jr.,': [1662, 2223], 'J.E.': [1663], 'Carbtree': [1664], 'G.R.': [1665], '1992;': [1667], '355:': [1668], '457-461Crossref': [1669], '(369)': [1672], 'Recently,': [1675], 'conditional': [1677], 'gene': [1678, 4299], 'knockout': [1679], 'mice': [1683, 2901], 'confirmed': [1684], 'important': [1689], 'vivo': [1691], 'regulator': [1692], 'homeostasis': [1698], 'apolipoproteins': [1700], '(apoAI,': [1701], '-II,': [1702], '-IV,': [1704], 'apoB,': [1705], 'apoCII': [1706], '-III,': [1708], 'apoE),': [1710], 'microsomal': [1711], 'triglyceride': [1712], 'protein,': [1714, 2696, 2768], 'cholesterol': [1715], '7α-hydroxylase': [1716], '(CYP7A),': [1717], '(LFABP),': [1721], 'PPAR-α': [1723], '(24Hayhurst': [1724], 'G.P.': [1725], 'Lee': [1726], 'Y.H.': [1727], 'Lambert': [1728], 'Ward': [1730], 'J.M.': [1731], 'Gonzalez': [1732], 'F.J.': [1733, 3619], '21:': [1738], '1393-1403Crossref': [1739], '(862)': [1742], 'study': [1746], 'which': [1748, 3600, 4206], '9000': [1749], 'analyzed': [1752, 3537], 'cDNA': [1754, 4261, 4329], 'microarray': [1755], 'technology': [1756], 'human': [1758, 4332], 'overexpressed': [1762], 'demonstrated': [1764, 3938], '26': [1766], '45': [1769], 'HNF-4α-sensitive': [1770], 'related': [1773], '(25Naiki': [1777], 'Nagaki': [1779], 'Shidoji': [1781], 'Kojima': [1783], 'Imose': [1785], 'Kato': [1787], 'Ohnishi': [1789], 'Yagi': [1791], 'Moriwaki': [1793], '14011-14019Abstract': [1800], 'bind': [1816], 'nanomolar': [1819], 'have': [1822, 3683, 3712, 3735], 'reported': [1824], 'modulate': [1826], 'metabolism,': [1828], 'known': [1832, 4213], 'if': [1833], 'interacts': [1836, 1846], 'at': [1840, 1850, 2158, 2669, 2698, 2729, 2934, 2951, 2977, 2989, 3197, 3216, 3230, 3245, 3461, 3955, 3985], 'molecular': [1842, 2275], 'level,': [1843, 1853], 'cellular': [1852], 'influences': [1858], 'transcriptional': [1860], 'functions.': [1861], 'Materials—Recombinant': [1862], 'mouse': [1863, 2581, 2678, 2691, 2694, 3277, 4250, 4297], 'produced': [1866], 'purified': [1868, 2437], 'described': [1870, 1898, 2378, 2446, 2508, 2796, 2850, 3878, 4088, 4302], 'HNF-α-LBD': [1894], 'obtained': [1896, 2248, 2376, 3097, 3570, 4006], 'earlier': [1899, 2447, 2509, 3879], 'Fetal': [1943], 'bovine': [1944, 1946, 2712, 3136, 3208], 'serum,': [1945], 'serum': [1947, 2713, 3209], 'albumin,': [1948], 'A-Sepharose': [1950, 2703], '4CL,': [1951], 'FITC-goat': [1952], 'anti-rat': [1953, 2369, 2372, 2842, 3056, 3269], 'IgG,': [1954, 2024, 3291], 'protease': [1956, 2598], 'inhibitor': [1957, 2599], 'mixture': [1958, 2600, 3033, 3053], 'purchased': [1960, 1967, 1993, 2012, 2082, 4272], 'Sigma.': [1962], 'Lab-Tek': [1963], 'coverglass': [1964], 'slides': [1965, 3141, 3183], 'Fisher.': [1969], 'Mouse': [1970, 2590, 2899], 'anti-firefly': [1971, 3278], 'monoclonal': [1973, 3280], 'antibody': [1974, 3335, 3352], 'Novus': [1977], 'Biologicals': [1978], '(Littleton,': [1979], 'CO).': [1980], 'Rabbit': [1981, 3268], 'polyclonal': [1982, 2002, 2368, 2570, 2573, 2846], 'against': [1984, 2004, 2687, 3202], 'α': [1987], '(GR)': [1988], 'Santa': [1995], 'Cruz': [1996], 'Biotechnology': [1997], '(Santa': [1998], 'Cruz,': [1999], 'CA).': [2000], 'Gold-labeled': [2001], 'rabbit': [2005, 2841, 3042], 'IgG': [2006, 2045, 2866, 2884, 3300, 3870, 3874], '(Aurion,': [2007], 'Wageningen,': [2008], 'Netherlands)': [2010], 'through': [2013, 2908, 3445, 3469, 3487, 3506, 3963, 3967, 3975, 4023, 4027, 4037, 4058], 'Electron': [2014], 'Microscopy': [2015, 2897], 'Sciences': [2016], '(Fort': [2017], 'Washington,': [2018], 'PA).': [2019], 'Texas': [2020, 3287, 3455, 3520], 'Red': [2021, 3288, 3456, 3521], 'goat': [2022, 2043, 2864, 2882, 3055, 3063, 3289, 3293, 3298], 'anti-rabbit': [2023, 2865, 2883, 3064, 3290], 'TOTO-3': [2025, 3491], '(a': [2026], 'DNA': [2027, 2079, 3319, 4223], 'staining': [2028, 3317], 'dimeric': [2029, 3323], 'cyanine': [2030, 3324], 'fluorophore),': [2031], 'SlowFade': [2033], 'kit': [2034, 2504, 2558], 'Probes': [2038], '(Eugene,': [2039], 'OR).': [2040], 'FluoroLink': [2041, 3296], 'Cy5-labeled': [2042, 2548, 3297, 3872, 3928], 'anti-mouse': [2044, 3273, 3299], 'Amersham': [2048, 2560], 'Biosciences.': [2049], 'pCi-neo,': [2054], 'Renilla': [2055], 'pRL-CMV,': [2059], 'dual': [2060], 'assay': [2063], 'system,': [2064], 'CheckMate': [2066], 'system': [2069, 3405], 'Promega': [2072, 4274], '(Madison,': [2073, 4275], 'WI).': [2074, 4276], 'LipofectAMINE': [2075], '2000,': [2076], 'transfections,': [2080], 'Invitrogen.': [2084], 'All': [2085, 3070], 'reagents': [2086], 'solvents': [2088], 'highest': [2093], 'grade': [2094], 'culture': [2099, 3131, 3156], 'tested': [2100, 2760, 3354], 'necessary.': [2102], 'CD': [2103, 2135, 2176, 2200, 2236, 2353], 'HNF-4α-LBD—Far-UV': [2107], 'circular': [2108], 'dichroic': [2109], 'spectra': [2110, 2201, 2252], 'HNF-4α-LBD': [2112, 2255, 2283, 2295, 2322, 2360, 2373], '2': [2116, 2172, 2316, 2727], 'mm': [2117, 2126, 2625, 2630, 2737], 'Tri-HCl,': [2118], 'pH': [2119, 2627, 2924], '8,': [2120, 2628], 'containing': [2121, 2597, 2963, 3133], '0.5%': [2122, 2635], 'glycerol': [2123], '0.05': [2125], 'dithiothreitol': [2127], 'measured': [2129], 'separately': [2130, 2259], 'mixture.': [2133, 2271], 'measurements': [2136, 4079, 4152], 'performed': [2138, 2794, 3399, 3556, 3774], 'J-710': [2141], 'Spectropolarimeter': [2142], '(Jasco,': [2143], 'Baltimore,': [2144], 'MD)': [2145], 'using': [2146, 2203, 2500, 2551, 3337, 3538, 4290], '1-mm': [2148], 'cuvette.': [2149], 'Spectra': [2150], 'recorded': [2152, 2258, 3979, 4016], '250': [2154], '195': [2156], '50': [2159, 2624, 4162, 4216], 'nm/min': [2160], 'time': [2163], 'constant': [2164], '1': [2166, 2949, 2975, 3214, 3228, 3243], 's': [2167], 'bandwidth': [2170], 'nm.': [2173], 'For': [2174, 2310, 2479, 4277], 'profile': [2177], 'average': [2179, 3559, 4145], '10': [2181], 'scans': [2182], 'obtained.': [2184], 'Percentages': [2185], 'various': [2187], 'structures': [2189], 'HNF-4α-LBD,': [2191, 2477], '(HNF-4α-LBD': [2194], '+': [2195, 2240, 4199], 'ACBP)': [2196], 'calculated': [2198, 3594, 3635, 4110, 4150, 4166], 'CDstr': [2205], 'program': [2206], '(26Hennessey': [2207], 'J.P.': [2208], 'Johnson': [2209, 2222], 'W.C.': [2210, 2224], '1981;': [2212], '20:': [2213], '1085-1094Crossref': [2214], '(574)': [2217], '27Compton': [2220], 'L.A.': [2221], 'Anal.': [2225], '1986;': [2227], '155:': [2228], '155-167Crossref': [2229], '(485)': [2232], 'spectrum': [2237, 2247], '(ACBP': [2239], 'HNF-4α-LBD)': [2241], 'compared': [2243], 'theoretical': [2246], 'summing': [2250], 'concentration': [2265, 2345, 2778, 3373], 'equal': [2266], 'Because': [2272], 'weight': [2276], 'difference': [2277], '(10,000': [2280], 'Da)': [2281], '132-455;': [2286], '36,172': [2287], 'Da),': [2288], '4': [2289, 2699, 2730, 2952, 2978], 'μm': [2290, 2294, 2317, 2321], '1.11': [2293], 'solutions': [2296], 'used,': [2298], 'respectively,': [2299, 2697], 'such': [2300, 3997], 'molar': [2303], 'concentrations': [2304, 2331], 'amino': [2306, 2333, 2347], 'equivalent.': [2309], 'mixtures': [2311], 'two': [2314, 2337, 3589, 3641], 'proteins,': [2315], '0.56': [2320], 'maintain': [2329, 2341], 'equivalent': [2330], 'same': [2343, 2946, 3969], 'total': [2344], 'proteins.': [2357], 'Antisera': [2361], 'Coimmunoprecipitation,': [2363], 'Western': [2364, 2441, 2755, 2772, 2776, 2838], 'Blotting,': [2365], 'Immunocytochemistry—Rabbit': [2367], 'antisera': [2374, 2472, 3281], 'previously': [2379], 'appropriate': [2433], 'dilutions': [2434, 3345], 'anti-ACBP': [2438, 2494, 2571, 3023, 3873], 'blotting': [2442, 2773, 2839], '(28Sambrook': [2448], 'Fritsch': [2450], 'E.F.': [2451], 'Maniatis': [2452], 'Cloning:': [2455], 'Laboratory': [2457, 2464], 'Manual,': [2458], '2nd': [2459], 'Ed.': [2460], 'Cold': [2461, 2466], 'Spring': [2462, 2467], 'Harbor': [2463], 'Press,': [2465], 'Harbor,': [2468], 'NY1989Google': [2469], 'Anti-ACBP': [2471], 'cross-react': [2475], '(FRET)': [2484], 'microscopy,': [2490, 3917], 'pure': [2491, 2540], 'fractions': [2492], 'IgGs': [2497, 2541], 'prepared': [2499, 2848], 'Econo-Pac': [2502], 'Bio-Rad': [2506], '(29Wouters': [2510, 3880, 4089], 'Bastiaens': [2512, 3882, 4091], 'P.I.': [2513, 3883, 4092], 'Wirtz': [2514, 3884, 4093], 'K.W.': [2515, 3885, 4094], 'Jovin': [2516, 3886, 4095], 'EMBO': [2518, 3888, 4097], '17:': [2521, 3891, 4100], '7179-7189Crossref': [2522, 3892, 4101], '(180)': [2525, 3895, 4104], '30Kenworthy': [2528, 3898], 'A.K.': [2529, 3899], 'Methods.': [2530, 3900], '24:': [2532, 3902], '289-296Crossref': [2533, 3903], '(446)': [2536, 3906], 'Cy3-labeled': [2544, 3868], '(anti-HNF-4α': [2545], 'IgG)': [2546, 2550], '(anti-ACBP': [2549], 'Fluorolink-antibody': [2553], 'Cy3': [2554, 3458, 3934, 3954, 3965, 4025, 4075, 4154, 4178], 'Cy5': [2556, 3495, 3530, 3936, 3945, 3984, 4003, 4019, 4043, 4054, 4069, 4131, 4142, 4159, 4180], 'labeling': [2557], 'Biosciences': [2561], 'according': [2562, 3651, 4111, 4194], "manufacturer's": [2565], 'instructions.': [2566], 'Coimmunoprecipitation—The': [2567], 'ability': [2568], 'anti-HNF-4α-LBD': [2574], 'antiserum': [2575, 3024], 'coimmunoprecipitate': [2577], 'homogenate': [2583], 'tested.': [2589], 'diced': [2593], 'RIPA': [2595, 2620, 2716, 2740], 'buffer': [2596, 2604, 2621, 2749, 2962], '(1': [2601], 'ml': [2602], 'per': [2605], '200': [2606], 'mg': [2607], 'tissue)': [2610], 'subjected': [2612], '30': [2614, 3195], 'strokes': [2615], 'Dounce': [2618], 'homogenizer.': [2619], 'consisted': [2622], 'Tris,': [2626], '150': [2629], 'NaCl,': [2631], '1%': [2632], 'Nonidet': [2633], 'P-40,': [2634], 'deoxycholate,': [2636], '0.1%': [2637], 'SDS': [2638], '(31Uittenbogaard': [2639], 'Ying': [2641], 'Y.S.': [2642], 'Smart': [2643], 'E.J.': [2644], '6525-6532Abstract': [2650], '(272)': [2658], 'Unbroken': [2661], 'debris': [2664], 'removed': [2666], 'centrifugation': [2668], '600': [2670], '×': [2671], 'g': [2672], '5': [2674, 2930], 'min.': [2675], 'Homogenates': [2676], 'incubated': [2684, 2725, 3050, 3223], 'rat-HNF-4α-LBD,': [2690], 'GR,': [2692], '°C': [2700, 2953, 2979, 2991], 'overnight.': [2701], 'Protein': [2702, 2783], '4CL': [2704], 'blocked': [2706, 3201], 'nonspecific': [2708, 3203, 3359], '2%': [2711, 2982], 'albumin': [2714], 'buffer,': [2717, 2741, 2923], 'added': [2718], 'overnight': [2721], 'immunoprecipitated': [2722], 'complexes,': [2723], 'h': [2728, 2950, 2976, 3215, 3229, 3244], '°C.': [2731], 'After': [2732, 2929, 3248], 'extensive': [2733, 3249], 'washings': [2734], '500': [2736], 'NaCl': [2738], 'beads': [2743], 'solubilized': [2745], '2×': [2747], 'sample': [2748, 3444], 'further': [2751, 4169], 'SDS-PAGE': [2752, 2786], 'separation': [2753, 3365], 'blotting.': [2756], 'immunoprecipitates': [2758], 'HNF-4α,': [2766], 'GR': [2770], 'follows.': [2775, 3972], 'Blotting—Protein': [2777], 'BCA': [2782], 'Assay': [2784], '(Pierce).': [2785], 'nitrocellulose': [2791], '32Laemmli': [2823], 'U.K.': [2824], '1970;': [2826], '227:': [2827], '680-685Crossref': [2828], '(207192)': [2831], 'Primary': [2834], 'anti-rat-HNF-4α-LBD': [2845], 'above.': [2851], 'Specific': [2852], 'visualized': [2855], 'either': [2856, 3035, 3338], 'colorimetric': [2859], 'method': [2860, 2878], 'utilizing': [2861], 'alkaline': [2862], 'phosphatase-conjugated': [2863], '5-bromo-4-chloro-3-indolyl': [2868], 'phosphate/nitro': [2869], 'blue': [2870, 3528, 3787], 'tetrazolium': [2871], 'substrate': [2872], '(Sigma)': [2873], 'chemiluminescent': [2877], 'employing': [2879], 'horseradish': [2880], 'peroxidase-conjugated': [2881], 'luminol/hydrogen': [2886], 'peroxide': [2887], '(Amersham': [2889], 'Biosciences).': [2890], 'Detection': [2891], 'ACBP·HNF-4α': [2893], 'Complexes': [2894], 'Immunoelectron': [2896], 'Liver—Four-month-old': [2900], 'anesthetized': [2903], 'tribromoethanol': [2905], 'perfused': [2907], 'left': [2910], 'heart': [2911], 'ventricle': [2912], '3%': [2914], 'formaldehyde,': [2915], '0.05%': [2916], 'glutaraldehyde': [2917], '0.1': [2919, 2958], 'm': [2920, 2959], 'sodium': [2921, 2960], 'phosphate': [2922, 2961], '7.3,': [2925], '3.2%': [2927], 'sucrose.': [2928, 2965], 'min': [2931, 3196, 3990], 'perfusion': [2933], '24': [2935], '°C,': [2936, 3199], 'collected,': [2940], 'minced,': [2941], 'immersed': [2943], 'fixative': [2947], 'washed': [2956, 3048, 3185], '3.5%': [2964], 'tissue': [2967, 3009], 'treated': [2969], '0.25%': [2971], 'tannic': [2972], 'uranyl': [2983, 3078], 'acetate': [2984, 3079], '70%': [2986], 'ethanol': [2987, 3000], 'cooled': [2988], '-35': [2990], '40': [2993], 'min,': [2994], 'dehydrated': [2997], 'series': [3001], 'embedded': [3003], 'Lowicryl': [3005], 'K4M': [3006], 'resin.': [3007], 'Ultrathin': [3008], 'sections': [3010, 3046, 3071], '(50-60': [3011], 'placed': [3014], 'Formvar-coated': [3016], 'nickel': [3017], 'grids': [3018], 'immunogold': [3020], 'stained': [3021], 'raised': [3025, 3040], '(diluted': [3028, 3043], '1:50-1:80)': [3029], 'alone': [3030], 'anti-HNF-4α': [3036, 3869], 'anti-glucocorticoid': [3038], 'receptor,': [3039], '1:150).': [3044], 'conjugated': [3057, 3065], '6-nm': [3059], 'gold': [3060, 3068], 'particles': [3061], '15-nm': [3067], 'particles.': [3069], 'post-stained': [3073], 'briefly': [3075], 'aqueous': [3077], "Reynold's": [3081], 'lead': [3082], 'citrate': [3083], 'examined': [3085], 'Zeiss': [3088, 3447], '10c': [3089], 'transmission': [3090], 'microscope.': [3092], 'Cell': [3093, 3384], 'Culture—COS-7': [3094], 'American': [3100], 'Type': [3101], 'Culture': [3102], 'Collection': [3103], '(ATCC,': [3104], 'Manassas,': [3105], 'VA).': [3106], 'Rat': [3107, 3909], 'T-7': [3110], 'generously': [3112], 'provided': [3113], 'Dr.': [3115], 'Charles': [3116], 'Baum': [3117], '(University': [3118], 'Chicago,': [3120], 'Chicago).': [3121], 'grown': [3125, 3178], "glucose/Dulbecco's": [3128], 'modified': [3129], "Eagle's": [3130], 'medium': [3132], '10%': [3134, 3206], 'fetal': [3135, 3207], 'serum.': [3137], '4-Well': [3138], 'LabTek': [3139, 3181], 'chamber': [3140, 3182], 'immunofluorescence': [3146, 3916], 'experiments,': [3149], '6-well': [3151], 'plates': [3152], '10-cm': [3154], 'dishes': [3157], 'all': [3159, 3678, 3693, 3708, 3724], 'other': [3161], 'purposes': [3162], 'transfection': [3164], 'experiments).': [3165], 'Preparation': [3166], 'Cells': [3168], 'Indirect': [3170], 'Immunofluorescence': [3171], 'Microscopy—': [3172], '4-well': [3180], "Hanks'": [3187, 3211, 3255], 'solution,': [3188, 3256], 'fixed': [3189], '70:30': [3191], 'acetone/ethanol': [3192], '(v/v)': [3193], '-20': [3198], 'solution': [3212], 'room': [3217, 3231, 3246], 'temperature.': [3218, 3247], 'primary': [3225, 3285, 3334, 3349, 3921], 'temperature,': [3232], 'followed': [3233], 'incubation': [3235], 'fluorescently': [3237], 'labeled': [3238], 'another': [3242], 'washing': [3250], 'mounted': [3260], 'use': [3263], 'Slow': [3265], 'Fade': [3266], 'kit.': [3267], 'polyclonal,': [3271, 3275], 'antibodies.': [3286, 3305, 3343], 'FITC': [3292, 3475], 'anti-rat-IgG,': [3294], 'some': [3307, 3961], 'experiments': [3308], 'areas': [3311], 'defined': [3315], 'TOTO-3,': [3321], 'fluorophore.': [3325], 'Specificity': [3326], 'immunostaining': [3328], 'deleting': [3332], 'one': [3339, 3801, 4066], '(1:20-1:200)': [3346], 'optimized.': [3356], 'This': [3357], 'minimized': [3358], 'adsorption': [3360], 'fluorescent': [3362, 3368], 'antibodies,': [3363], 'ensured': [3364], 'signals,': [3369], 'optimized': [3371, 3996], 'fluorophore': [3372], 'preclude': [3375], 'self-quenching': [3376], '(33Musch': [3377], 'Cohen': [3379], 'Rodriguez-Boulan': [3381], 'E.': [3382], '138:': [3387], '291-306Crossref': [3388], '(159)': [3391], 'Image': [3396, 3544], 'Analysis—LSCM': [3397], 'MRC-1024': [3402], 'imaging': [3404], '(Bio-Rad)': [3406], 'consisting': [3407], 'Axiovert': [3410], '135': [3411], 'microscope': [3412], '(Zeiss,': [3413], 'York)': [3415], 'equipped': [3416], 'three': [3418, 3763, 3793, 3797], 'independent': [3419, 3812], 'low': [3420], 'noise': [3421], 'photomultiplier': [3422], 'tube': [3423], 'channels.': [3424], 'excitation': [3426, 3952], 'light': [3427, 3501, 3516], '(λ': [3428], '=': [3429, 3657, 3663, 4114, 4197], '488,': [3430], '568,': [3431], '647': [3433, 3499, 3986], '15-milliwatt': [3437], 'krypton-argon': [3438], 'delivered': [3441], '×63': [3446], 'Plan-Fluor': [3448], 'oil': [3449], 'immersion': [3450], 'objective,': [3451], 'numerical': [3452], 'aperture': [3453], '1.45.': [3454], 'excited': [3460, 3477, 3497], '568': [3462, 3956], 'nm,': [3463, 3957], 'their': [3465, 3503], 'emission': [3466, 3484, 3504, 3943, 3966, 3974, 4010, 4026, 4036, 4052, 4156], 'HQ': [3471], '585/40': [3472], 'bandpass': [3473, 3509, 3949, 4031], 'filter.': [3474, 3490, 3510], '488': [3479], 'light,': [3481], 'its': [3483], 'selected': [3486, 3505], '540/30': [3489], '(DNA': [3492], 'stain)': [3493], '680/32': [3508, 3948, 3976, 4030, 4039], 'conventional': [3512], 'colors': [3513], 'emitted': [3515], 'red': [3518, 3645, 3679, 3695, 3714, 3779, 3789], '(for': [3519, 3525, 3529], 'Cy3),': [3523], 'green': [3524, 3648, 3685, 3709, 3725, 3781, 3785], 'FITC),': [3526], 'TOTO-3).': [3532], 'Images': [3533], 'acquired': [3535], 'LaserSharp': [3539, 3579, 3734], '(from': [3540, 3546], 'Bio-Rad)': [3541], 'MetaMorph': [3543], 'Analysis': [3545], 'Advanced': [3547], 'Scientific': [3548], 'Imaging,': [3549], 'Meraux,': [3550], 'LA)': [3551], 'software.': [3552], 'Colocalization': [3553], 'analysis': [3554], '20': [3561], 'four': [3564], 'different': [3565, 3642, 3798, 3835, 4163], 'wells,': [3566], 'results': [3569], 'are': [3571], 'representative': [3575], 'set': [3576, 4245], 'version': [3580], '3.0': [3581], 'software': [3582, 3634, 3809], 'colocalization': [3586, 3637, 3782, 3799], 'analysis,': [3587], '(colocalization': [3591], 'coefficients)': [3592], 'based': [3595], "Pearson's": [3597], 'coefficient,': [3599], 'well': [3603], 'established': [3604], 'means': [3605, 3756], 'describing': [3607], 'degree': [3609], 'overlap': [3611], 'patterns': [3613], 'images': [3615, 3765], '(34Manders': [3616], 'E.M.M.': [3617], 'Verbeek': [3618], 'Aten': [3620], 'Microsc.': [3623], '(Oxf.).': [3624], '169:': [3626], '375-382Crossref': [3627], '(1527)': [3630], '(coloc)': [3638], 'coefficients': [3639, 3731], 'fluorophores,': [3643], 'designated': [3644], '(R)': [3646], '(G)': [3649], 'herein,': [3650], 'following': [3654, 4239], 'equations:': [3655], 'Cred': [3656], 'Σ': [3658, 3664, 3670, 3687, 3700, 3716], 'Ri,coloc/Σ': [3659], 'Ri': [3660, 3688], 'Cgreen': [3662], 'Gi,coloc/Σ': [3665], 'Gi.': [3666], 'equations': [3669], 'Ri,coloc': [3671], 'represents': [3672, 3702], 'sum': [3674, 3691, 3704, 3720, 4048], 'intensities': [3676, 3706, 3722], 'pixels': [3680, 3696, 3710, 3726, 3837], 'component;': [3686, 3715], 'image;': [3699], 'Gi,coloc': [3701], 'Gi': [3717], 'image.': [3729], 'generated': [3732, 3824], '0': [3738, 3744], '1;': [3740], 'value': [3742, 3753, 4146], 'indicates': [3745], 'there': [3747, 3757], 'no': [3749], 'colocalization,': [3750], 'whereas': [3751], '1.0': [3755], 'complete': [3759], 'colocalization.': [3760], 'Similarly,': [3761], 'channel': [3764, 3794], '(designated': [3766], 'red,': [3767], 'green,': [3768], 'blue,': [3770], 'respectively)': [3771], 'analyses': [3772, 3795], 'compare': [3778], 'but': [3783], 'blue.': [3791], 'yielded': [3796], 'coefficients,': [3800], 'pair': [3804], 'color': [3806], 'combinations.': [3807], 'allowed': [3810], 'background': [3813], 'selection': [3814], 'subtraction': [3816], 'before': [3817, 3980, 4041, 4141], 'calculation': [3818], 'coefficients.': [3821], 'Fluorograms': [3822], 'entire': [3827], 'image,': [3828], 'displaying': [3829], 'intensity': [3831, 4011, 4034, 4129, 4140], 'distribution': [3833], 'colored': [3836], 'merged': [3840], 'image': [3841, 4015], 'scattergram.': [3844], 'FRET': [3845, 3866, 3932, 4073, 4081, 4107, 4121, 4209, 4221], 'Microscopy—In': [3846], 'estimate': [3849, 4172], 'molecules': [3857], 'images,': [3865], 'processed': [3913], 'except': [3918], 'had': [3924], 'Cy3-': [3926], 'used.': [3930], 'Qualitatively,': [3931], 'detection': [3940], 'sensitized': [3942, 4051], '(through': [3946], 'filter)': [3950], 'upon': [3951], 'after': [3958, 3982, 4017, 4068, 4130, 4158], 'correction': [3959], 'bleed': [3962, 4022, 4057], 'filter': [3970, 3977, 4040], 'Fluorescence': [3973, 4033], 'photobleaching': [3983, 3994, 4018, 4042, 4160], '3': [3989], '(the': [3991], 'duration': [3992], 'good': [4000], 'decrease': [4001], 'without': [4007], 'affecting': [4008], 'Cy3).': [4013], 'PMT3': [4028], '(with': [4029], 'filter).': [4032], '(FRET': [4044], 'acceptor),': [4045], 'being': [4046], 'resulted': [4049], 'Cy5,': [4060], 'always': [4062], 'higher': [4063], 'than': [4064], 'taken': [4067], 'photobleaching,': [4070], 'clearly': [4071], 'indicating': [4072], 'Cy5.': [4077], 'Quantitative': [4078], 'efficiency': [4082, 4108, 4210], 'estimation': [4083], 'carried': [4085], 'out': [4086], 'E': [4113, 4119, 4148, 4167, 4196], '(Ipost': [4115], '-': [4116], 'Ipre)/Ipost,': [4117], 'where': [4118, 4201], 'efficiency;': [4122], 'Ipost': [4123], 'acceptor': [4126, 4137], '(Cy3)': [4127, 4138], 'photobleach,': [4132], 'Ipre': [4134], 'photobleach.': [4143], 'An': [4144], 'R,': [4173], '(distance': [4181], 'ultimately': [4182], 'dictated': [4183], 'experiment': [4186], 'proximity': [4189], 'HNF-4α),': [4193], '1/(1': [4198], '(R/R0)6),': [4200], 'R0,': [4202], '50%': [4208], 'occurs,': [4211], 'Cy3/Cy5': [4220], 'pair.': [4222], 'Constructs': [4224], 'Plasmids': [4226], 'Used': [4227], 'Transfection': [4229], 'Assays—COS-7': [4230], 'plasmids.': [4243], 'sense': [4247], 'vectors': [4253], 'constructed': [4255, 4289], 'inserting': [4257], '276-bp': [4259], 'into': [4262], 'XhoI': [4264], 'cloning': [4265], 'site': [4266], 'pCI-neo': [4268], 'efficient': [4279], 'repression': [4280], 'expression,': [4283], 'pUC': [4292], 'contained': [4295], 'pgk-1': [4298], 'promoter,': [4300], '(35Adra': [4303], 'C.N.': [4304], 'Boer': [4305], 'P.H.': [4306], 'McBurney': [4307], 'M.W.': [4308], 'Gene': [4309], '(Amst.).': [4310], '1987;': [4311], '60:': [4312], '65-74Crossref': [4313], '(307)': [4316], 'pLEN4S,': [4323], '3-kb': [4326], 'HNF-4α1': [4328], 'under': [4330], 'metallothionein': [4333]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1969026949', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 8}], 'updated_date': '2025-01-12T05:36:57.158105', 'created_date': '2016-06-24'}