E-C Coupling Alterations and Spontaneous Activity in Mice Carrying Cardiac Troponin T Mutations

Name: Work Video:
Duration: 3 min 30 s
José Manuel Pioner; Raffaele Coppini; Cecilia Ferrantini; Benedetta Tosi; Luca Mazzoni; Rachel Moore; Elisabetta Cerbai; Alessandro Mugelli; Jil C. Tardiff; Chiara Tesi; Corrado Poggesi
{'id': 'https://openalex.org/W1968719617', 'doi': 'https://doi.org/10.1016/j.bpj.2013.11.3567', 'title': 'E-C Coupling Alterations and Spontaneous Activity in Mice Carrying Cardiac Troponin T Mutations', 'display_name': 'E-C Coupling Alterations and Spontaneous Activity in Mice Carrying Cardiac Troponin T Mutations', 'publication_year': 2014, 'publication_date': '2014-01-01', 'ids': {'openalex': 'https://openalex.org/W1968719617', 'doi': 'https://doi.org/10.1016/j.bpj.2013.11.3567', 'mag': '1968719617'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.bpj.2013.11.3567', 'pdf_url': 'http://www.cell.com/article/S0006349513048261/pdf', 'source': {'id': 'https://openalex.org/S98085912', 'display_name': 'Biophysical Journal', 'issn_l': '0006-3495', 'issn': ['0006-3495', '1542-0086'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://www.cell.com/article/S0006349513048261/pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5059236440', 'display_name': 'José Manuel Pioner', 'orcid': 'https://orcid.org/0000-0003-0179-3033'}, 'institutions': [], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Josè Manuel Pioner', 'raw_affiliation_strings': ['Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048771701', 'display_name': 'Raffaele Coppini', 'orcid': 'https://orcid.org/0000-0002-4096-3173'}, 'institutions': [], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Raffaele Coppini', 'raw_affiliation_strings': ['Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059284373', 'display_name': 'Cecilia Ferrantini', 'orcid': 'https://orcid.org/0000-0002-3757-1363'}, 'institutions': [], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Cecilia Ferrantini', 'raw_affiliation_strings': ['Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113480577', 'display_name': 'Benedetta Tosi', 'orcid': None}, 'institutions': [], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Benedetta Tosi', 'raw_affiliation_strings': ['Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025696719', 'display_name': 'Luca Mazzoni', 'orcid': 'https://orcid.org/0000-0002-4460-5971'}, 'institutions': [], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Luca Mazzoni', 'raw_affiliation_strings': ['Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068376405', 'display_name': 'Rachel Moore', 'orcid': 'https://orcid.org/0000-0003-2388-071X'}, 'institutions': [{'id': 'https://openalex.org/I138006243', 'display_name': 'University of Arizona', 'ror': 'https://ror.org/03m2x1q45', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I138006243']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Rachel Moore', 'raw_affiliation_strings': ['University of Arizona College of Medicine Tucson, AZ, USA.'], 'affiliations': [{'raw_affiliation_string': 'University of Arizona College of Medicine Tucson, AZ, USA.', 'institution_ids': ['https://openalex.org/I138006243']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074039900', 'display_name': 'Elisabetta Cerbai', 'orcid': 'https://orcid.org/0000-0001-7839-1361'}, 'institutions': [], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Elisabetta Cerbai', 'raw_affiliation_strings': ['Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005919863', 'display_name': 'Alessandro Mugelli', 'orcid': 'https://orcid.org/0000-0002-1649-9702'}, 'institutions': [], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Alessandro Mugelli', 'raw_affiliation_strings': ['Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072803970', 'display_name': 'Jil C. Tardiff', 'orcid': 'https://orcid.org/0000-0003-4291-4882'}, 'institutions': [{'id': 'https://openalex.org/I138006243', 'display_name': 'University of Arizona', 'ror': 'https://ror.org/03m2x1q45', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I138006243']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jil Tardiff', 'raw_affiliation_strings': ['University of Arizona College of Medicine Tucson, AZ, USA.'], 'affiliations': [{'raw_affiliation_string': 'University of Arizona College of Medicine Tucson, AZ, USA.', 'institution_ids': ['https://openalex.org/I138006243']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028274993', 'display_name': 'Chiara Tesi', 'orcid': 'https://orcid.org/0000-0002-1111-1473'}, 'institutions': [], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Chiara Tesi', 'raw_affiliation_strings': ['Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5036638516', 'display_name': 'Corrado Poggesi', 'orcid': 'https://orcid.org/0000-0003-2624-4778'}, 'institutions': [], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Corrado Poggesi', 'raw_affiliation_strings': ['Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata (C.I.M.M.B.A.), Florence, Italy', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 66}, 'biblio': {'volume': '106', 'issue': '2', 'first_page': '644a', 'last_page': '644a'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10217', 'display_name': 'Cardiac electrophysiology and arrhythmias', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10217', 'display_name': 'Cardiac electrophysiology and arrhythmias', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10493', 'display_name': 'Ion channel regulation and function', 'score': 0.9816, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10882', 'display_name': 'Cardiomyopathy and Myosin Studies', 'score': 0.9804, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/ranolazine', 'display_name': 'Ranolazine', 'score': 0.57236195}, {'id': 'https://openalex.org/keywords/serca', 'display_name': 'SERCA', 'score': 0.5325137}], 'concepts': [{'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.6678876}, {'id': 'https://openalex.org/C2779177932', 'wikidata': 'https://www.wikidata.org/wiki/Q907104', 'display_name': 'Ranolazine', 'level': 2, 'score': 0.57236195}, {'id': 'https://openalex.org/C2781414619', 'wikidata': 'https://www.wikidata.org/wiki/Q24785512', 'display_name': 'SERCA', 'level': 4, 'score': 0.5325137}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.52584916}, {'id': 'https://openalex.org/C207200792', 'wikidata': 'https://www.wikidata.org/wiki/Q428914', 'display_name': 'Myocyte', 'level': 2, 'score': 0.4956392}, {'id': 'https://openalex.org/C24998067', 'wikidata': 'https://www.wikidata.org/wiki/Q4114622', 'display_name': 'Stimulation', 'level': 2, 'score': 0.49378785}, {'id': 'https://openalex.org/C36036425', 'wikidata': 'https://www.wikidata.org/wiki/Q7846262', 'display_name': 'Troponin', 'level': 3, 'score': 0.4326291}, {'id': 'https://openalex.org/C57900726', 'wikidata': 'https://www.wikidata.org/wiki/Q492905', 'display_name': 'Diastole', 'level': 3, 'score': 0.43124428}, {'id': 'https://openalex.org/C164705383', 'wikidata': 'https://www.wikidata.org/wiki/Q10379', 'display_name': 'Cardiology', 'level': 1, 'score': 0.42402017}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.36162895}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.3014002}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.10597226}, {'id': 'https://openalex.org/C84393581', 'wikidata': 'https://www.wikidata.org/wiki/Q82642', 'display_name': 'Blood pressure', 'level': 2, 'score': 0.09614098}, {'id': 'https://openalex.org/C23265538', 'wikidata': 'https://www.wikidata.org/wiki/Q300033', 'display_name': 'ATPase', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C500558357', 'wikidata': 'https://www.wikidata.org/wiki/Q12152', 'display_name': 'Myocardial infarction', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.bpj.2013.11.3567', 'pdf_url': 'http://www.cell.com/article/S0006349513048261/pdf', 'source': {'id': 'https://openalex.org/S98085912', 'display_name': 'Biophysical Journal', 'issn_l': '0006-3495', 'issn': ['0006-3495', '1542-0086'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.bpj.2013.11.3567', 'pdf_url': 'http://www.cell.com/article/S0006349513048261/pdf', 'source': {'id': 'https://openalex.org/S98085912', 'display_name': 'Biophysical Journal', 'issn_l': '0006-3495', 'issn': ['0006-3495', '1542-0086'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3196941726', 'https://openalex.org/W3123595055', 'https://openalex.org/W2464352721', 'https://openalex.org/W2395367366', 'https://openalex.org/W2379102826', 'https://openalex.org/W2101040186', 'https://openalex.org/W2072265441', 'https://openalex.org/W2053123608', 'https://openalex.org/W2047098488', 'https://openalex.org/W1978276670'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1968719617', 'counts_by_year': [], 'updated_date': '2024-12-09T15:47:08.152464', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
