Publication Information

{'id': 'https://openalex.org/W1968064237', 'doi': 'https://doi.org/10.1021/bi9009677', 'title': 'The Anti-Helminthic Niclosamide Inhibits Wnt/Frizzled1 Signaling', 'display_name': 'The Anti-Helminthic Niclosamide Inhibits Wnt/Frizzled1 Signaling', 'publication_year': 2009, 'publication_date': '2009-09-22', 'ids': {'openalex': 'https://openalex.org/W1968064237', 'doi': 'https://doi.org/10.1021/bi9009677', 'mag': '1968064237', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19772353', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2801776'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/bi9009677', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S104038378', 'display_name': 'Biochemistry', 'issn_l': '0006-2960', 'issn': ['0006-2960', '1520-4995', '1943-295X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc2801776?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5001541342', 'display_name': 'Minyong Chen', 'orcid': 'https://orcid.org/0000-0001-5910-6684'}, 'institutions': [{'id': 'https://openalex.org/I4210153043', 'display_name': 'Duke University Hospital', 'ror': 'https://ror.org/04bct7p84', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210126298', 'https://openalex.org/I4210144876', 'https://openalex.org/I4210153043']}, {'id': 'https://openalex.org/I4210126298', 'display_name': 'Duke Medical Center', 'ror': 'https://ror.org/03njmea73', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210126298', 'https://openalex.org/I4210144876']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Minyong Chen', 'raw_affiliation_strings': ['Department of Medicine Duke University Medical Center, Durham, North Carolina 27710 USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine Duke University Medical Center, Durham, North Carolina 27710 USA', 'institution_ids': ['https://openalex.org/I4210153043', 'https://openalex.org/I4210126298']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101851536', 'display_name': 'Jiangbo Wang', 'orcid': 'https://orcid.org/0000-0002-1117-7771'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Jiangbo Wang', 'raw_affiliation_strings': ['Departments of Medicine'], 'affiliations': [{'raw_affiliation_string': 'Departments of Medicine', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112368422', 'display_name': 'Jiuyi Lü', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Jiuyi Lu', 'raw_affiliation_strings': ['Departments of Medicine'], 'affiliations': [{'raw_affiliation_string': 'Departments of Medicine', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050012538', 'display_name': 'Michael C. Bond', 'orcid': 'https://orcid.org/0000-0001-5527-6758'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Michael C. Bond', 'raw_affiliation_strings': ['Departments of Medicine'], 'affiliations': [{'raw_affiliation_string': 'Departments of Medicine', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034868635', 'display_name': 'Xiu-Rong Ren', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Xiu-Rong Ren', 'raw_affiliation_strings': ['Departments of Medicine'], 'affiliations': [{'raw_affiliation_string': 'Departments of Medicine', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012804507', 'display_name': 'H. Kim Lyerly', 'orcid': 'https://orcid.org/0000-0002-0063-4770'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'H. Kim Lyerly', 'raw_affiliation_strings': ['Surgery'], 'affiliations': [{'raw_affiliation_string': 'Surgery', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5114006469', 'display_name': 'Larry S. Barak', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Larry S. Barak', 'raw_affiliation_strings': ['Cell Biology'], 'affiliations': [{'raw_affiliation_string': 'Cell Biology', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5100780046', 'display_name': 'Wei Chen', 'orcid': 'https://orcid.org/0000-0002-9934-4000'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Wei Chen', 'raw_affiliation_strings': ['Departments of Medicine'], 'affiliations': [{'raw_affiliation_string': 'Departments of Medicine', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.322, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 207, 'citation_normalized_percentile': {'value': 0.918299, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '48', 'issue': '43', 'first_page': '10267', 'last_page': '10274'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10929', 'display_name': 'Wnt/β-catenin signaling in development and cancer', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10929', 'display_name': 'Wnt/β-catenin signaling in development and cancer', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13157', 'display_name': 'Cancer-related gene regulation', 'score': 0.9937, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10814', 'display_name': 'Neuropeptides and Animal Physiology', 'score': 0.9587, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/niclosamide', 'display_name': 'Niclosamide', 'score': 0.93532944}, {'id': 'https://openalex.org/keywords/dishevelled', 'display_name': 'Dishevelled', 'score': 0.90308267}, {'id': 'https://openalex.org/keywords/lrp6', 'display_name': 'LRP6', 'score': 0.76139104}, {'id': 'https://openalex.org/keywords/lrp5', 'display_name': 'LRP5', 'score': 0.70130366}, {'id': 'https://openalex.org/keywords/internalization', 'display_name': 'Internalization', 'score': 0.42936933}], 'concepts': [{'id': 'https://openalex.org/C2776306103', 'wikidata': 'https://www.wikidata.org/wiki/Q418523', 'display_name': 'Niclosamide', 'level': 2, 'score': 0.93532944}, {'id': 'https://openalex.org/C107300179', 'wikidata': 'https://www.wikidata.org/wiki/Q41797887', 'display_name': 'Frizzled', 'level': 4, 'score': 0.9042641}, {'id': 'https://openalex.org/C2775928862', 'wikidata': 'https://www.wikidata.org/wiki/Q5282208', 'display_name': 'Dishevelled', 'level': 5, 'score': 0.90308267}, {'id': 'https://openalex.org/C137620995', 'wikidata': 'https://www.wikidata.org/wiki/Q155769', 'display_name': 'Wnt signaling pathway', 'level': 3, 'score': 0.9009743}, {'id': 'https://openalex.org/C170320316', 'wikidata': 'https://www.wikidata.org/wiki/Q18028667', 'display_name': 'LRP6', 'level': 4, 'score': 0.76139104}, {'id': 'https://openalex.org/C182819311', 'wikidata': 'https://www.wikidata.org/wiki/Q18028670', 'display_name': 'LRP5', 'level': 4, 'score': 0.70130366}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.652997}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.48546582}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.47106096}, {'id': 'https://openalex.org/C139770010', 'wikidata': 'https://www.wikidata.org/wiki/Q1339807', 'display_name': 'Internalization', 'level': 3, 'score': 0.42936933}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.42351973}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3727607}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.1511133}, {'id': 'https://openalex.org/C18903297', 'wikidata': 'https://www.wikidata.org/wiki/Q7150', 'display_name': 'Ecology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D051157', 'descriptor_name': 'Frizzled Receptors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009534', 'descriptor_name': 'Niclosamide', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D051153', 'descriptor_name': 'Wnt Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000969', 'descriptor_name': 'Antinematodal Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000969', 'descriptor_name': 'Antinematodal Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004705', 'descriptor_name': 'Endocytosis', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D004705', 'descriptor_name': 'Endocytosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051157', 'descriptor_name': 'Frizzled Receptors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049452', 'descriptor_name': 'Green Fluorescent Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D049452', 'descriptor_name': 'Green Fluorescent Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018613', 'descriptor_name': 'Microscopy, Confocal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009534', 'descriptor_name': 'Niclosamide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051153', 'descriptor_name': 'Wnt Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051176', 'descriptor_name': 'beta Catenin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D051176', 'descriptor_name': 'beta Catenin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/bi9009677', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S104038378', 'display_name': 'Biochemistry', 'issn_l': '0006-2960', 'issn': ['0006-2960', '1520-4995', '1943-295X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2801776', 'pdf_url': 'https://europepmc.org/articles/pmc2801776?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801776', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19772353', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2801776', 'pdf_url': 'https://europepmc.org/articles/pmc2801776?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.58}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 21, 'referenced_works': ['https://openalex.org/W1935863539', 'https://openalex.org/W1967803088', 'https://openalex.org/W1969892000', 'https://openalex.org/W1971032421', 'https://openalex.org/W1972747946', 'https://openalex.org/W1986724654', 'https://openalex.org/W1997282555', 'https://openalex.org/W2009684443', 'https://openalex.org/W2012336255', 'https://openalex.org/W2025472785', 'https://openalex.org/W2035192365', 'https://openalex.org/W2035809306', 'https://openalex.org/W2039435520', 'https://openalex.org/W2041856923', 'https://openalex.org/W2059857664', 'https://openalex.org/W2068017239', 'https://openalex.org/W2097689792', 'https://openalex.org/W2127084883', 'https://openalex.org/W2134344512', 'https://openalex.org/W2144030492', 'https://openalex.org/W2399410610'], 'related_works': ['https://openalex.org/W4292764309', 'https://openalex.org/W4206653363', 'https://openalex.org/W4205259833', 'https://openalex.org/W3170832957', 'https://openalex.org/W2913541467', 'https://openalex.org/W2155308439', 'https://openalex.org/W2148458527', 'https://openalex.org/W2104774845', 'https://openalex.org/W1968064237', 'https://openalex.org/W1512115582'], 'abstract_inverted_index': {'Wnt': [0, 20, 23, 47, 155], 'proteins': [1], 'bind': [2], 'to': [3, 7], 'seven-transmembrane': [4], 'Frizzled': [5, 59, 139], 'receptors': [6], 'mediate': [8], 'the': [9, 74, 80, 87, 110, 151], 'important': [10], 'developmental,': [11], 'morphogenetic,': [12], 'and': [13, 45, 97, 102, 118, 140, 142], 'stem': [14], 'cell': [15], 'related': [16], 'tissue-regenerative': [17], 'effects': [18], 'of': [19, 52, 89, 130, 149, 154], 'signaling.': [21, 48, 156], 'Dysregulated': [22], 'signaling': [24, 132, 136], 'is': [25], 'associated': [26], 'with': [27], 'many': [28], 'cancers.': [29], 'Currently,': [30], 'there': [31], 'are': [32], 'no': [33], 'drug': [34, 84], 'candidates': [35], 'or': [36], 'even': [37], 'tool': [38], 'compounds': [39], 'that': [40, 69, 79], 'modulate': [41], 'Wnt-mediated': [42], 'receptor': [43, 112], 'trafficking,': [44], 'subsequent': [46], 'We': [49, 76], 'examined': [50], 'libraries': [51], 'FDA-approved': [53], 'drugs': [54], 'for': [55, 86], 'their': [56], 'utility': [57], 'as': [58, 73, 126], 'internalization': [60], 'modulators,': [61], 'employing': [62], 'a': [63, 83, 127, 146], 'primary': [64], 'imaged-based': [65], 'GFP': [66], 'fluorescence': [67], 'assay': [68], 'uses': [70], 'Frizzled1': [71, 92, 111], 'endocytosis': [72], 'readout.': [75], 'now': [77], 'report': [78], 'anti-helminthic': [81], 'niclosamide,': [82], 'used': [85], 'treatment': [88], 'tapeworm,': [90], 'promotes': [91], 'endocytosis,': [93], 'downregulates': [94], 'Dishevelled-2': [95], 'protein,': [96], 'inhibits': [98], 'Wnt3A-stimulated': [99], 'β-catenin': [100], 'stabilization': [101], 'LEF/TCF': [103], 'reporter': [104], 'activity.': [105], 'Additionally,': [106], 'following': [107], 'niclosamide-mediated': [108], 'internalization,': [109], 'colocalizes': [113], 'in': [114], 'vesicles': [115], 'containing': [116], 'transferrin': [117], 'agonist-activated': [119], 'β2-adrenergic': [120], 'receptor.': [121], 'Therefore,': [122], 'niclosamide': [123], 'may': [124, 144], 'serve': [125], 'negative': [128], 'modulator': [129], 'Wnt/Frizzled1': [131], 'by': [133], 'depleting': [134], 'upstream': [135], 'molecules': [137], '(i.e.,': [138], 'Dishevelled)': [141], 'moreover': [143], 'provide': [145], 'valuable': [147], 'means': [148], 'studying': [150], 'physiological': [152], 'consequences': [153]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1968064237', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 13}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 15}, {'year': 2020, 'cited_by_count': 15}, {'year': 2019, 'cited_by_count': 23}, {'year': 2018, 'cited_by_count': 18}, {'year': 2017, 'cited_by_count': 14}, {'year': 2016, 'cited_by_count': 21}, {'year': 2015, 'cited_by_count': 25}, {'year': 2014, 'cited_by_count': 14}, {'year': 2013, 'cited_by_count': 9}, {'year': 2012, 'cited_by_count': 10}], 'updated_date': '2024-12-14T08:04:05.616149', 'created_date': '2016-06-24'}