Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1967642097', 'doi': 'https://doi.org/10.1212/01.wnl.0000228230.26044.a4', 'title': '[ <sup>11</sup> C]PIB in a nondemented population', 'display_name': '[ <sup>11</sup> C]PIB in a nondemented population', 'publication_year': 2006, 'publication_date': '2006-08-07', 'ids': {'openalex': 'https://openalex.org/W1967642097', 'doi': 'https://doi.org/10.1212/01.wnl.0000228230.26044.a4', 'mag': '1967642097', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16894106'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1212/01.wnl.0000228230.26044.a4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S79704628', 'display_name': 'Neurology', 'issn_l': '0028-3878', 'issn': ['0028-3878', '1526-632X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5077392976', 'display_name': 'Mark A. Mintun', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I170201317', 'display_name': 'University of Pittsburgh', 'ror': 'https://ror.org/01an3r305', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I170201317']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'M. A. Mintun', 'raw_affiliation_strings': ['From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.'], 'affiliations': [{'raw_affiliation_string': 'From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.', 'institution_ids': ['https://openalex.org/I170201317']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047264120', 'display_name': 'Gina N. LaRossa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2802503132', 'display_name': 'Services Hospital', 'ror': 'https://ror.org/0308pxz24', 'country_code': 'PK', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802503132']}, {'id': 'https://openalex.org/I170201317', 'display_name': 'University of Pittsburgh', 'ror': 'https://ror.org/01an3r305', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I170201317']}], 'countries': ['PK', 'US'], 'is_corresponding': False, 'raw_author_name': 'G. N. LaRossa', 'raw_affiliation_strings': ['From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.', 'Hospitalist Service'], 'affiliations': [{'raw_affiliation_string': 'Hospitalist Service', 'institution_ids': ['https://openalex.org/I2802503132']}, {'raw_affiliation_string': 'From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.', 'institution_ids': ['https://openalex.org/I170201317']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077054820', 'display_name': 'Yvette I. Sheline', 'orcid': 'https://orcid.org/0000-0002-6929-9659'}, 'institutions': [{'id': 'https://openalex.org/I170201317', 'display_name': 'University of Pittsburgh', 'ror': 'https://ror.org/01an3r305', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I170201317']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Y. I. Sheline', 'raw_affiliation_strings': ['From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.'], 'affiliations': [{'raw_affiliation_string': 'From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.', 'institution_ids': ['https://openalex.org/I170201317']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036470525', 'display_name': 'Carmen S. Dence', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I170201317', 'display_name': 'University of Pittsburgh', 'ror': 'https://ror.org/01an3r305', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I170201317']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'C. S. Dence', 'raw_affiliation_strings': ['From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.'], 'affiliations': [{'raw_affiliation_string': 'From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.', 'institution_ids': ['https://openalex.org/I170201317']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004213601', 'display_name': 'S. Y. Lee', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I170201317', 'display_name': 'University of Pittsburgh', 'ror': 'https://ror.org/01an3r305', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I170201317']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'S. Y. Lee', 'raw_affiliation_strings': ['From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.'], 'affiliations': [{'raw_affiliation_string': 'From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.', 'institution_ids': ['https://openalex.org/I170201317']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013971949', 'display_name': 'Robert H. Mach', 'orcid': 'https://orcid.org/0000-0002-7645-2869'}, 'institutions': [{'id': 'https://openalex.org/I170201317', 'display_name': 'University of Pittsburgh', 'ror': 'https://ror.org/01an3r305', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I170201317']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'R. H. Mach', 'raw_affiliation_strings': ['From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.'], 'affiliations': [{'raw_affiliation_string': 'From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.', 'institution_ids': ['https://openalex.org/I170201317']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036841670', 'display_name': 'William E. Klunk', 'orcid': 'https://orcid.org/0000-0001-5512-0251'}, 'institutions': [{'id': 'https://openalex.org/I170201317', 'display_name': 'University of Pittsburgh', 'ror': 'https://ror.org/01an3r305', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I170201317']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'W. E. Klunk', 'raw_affiliation_strings': ['From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.'], 'affiliations': [{'raw_affiliation_string': 'From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.', 'institution_ids': ['https://openalex.org/I170201317']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029440312', 'display_name': 'Chester A. Mathis', 'orcid': 'https://orcid.org/0000-0001-9811-0950'}, 'institutions': [{'id': 'https://openalex.org/I170201317', 'display_name': 'University of Pittsburgh', 'ror': 'https://ror.org/01an3r305', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I170201317']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'C. A. Mathis', 'raw_affiliation_strings': ['From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.'], 'affiliations': [{'raw_affiliation_string': 'From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.', 'institution_ids': ['https://openalex.org/I170201317']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084618289', 'display_name': 'Steven T. DeKosky', 'orcid': 'https://orcid.org/0000-0003-3743-2758'}, 'institutions': [{'id': 'https://openalex.org/I170201317', 'display_name': 'University of Pittsburgh', 'ror': 'https://ror.org/01an3r305', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I170201317']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'S. T. DeKosky', 'raw_affiliation_strings': ['From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.'], 'affiliations': [{'raw_affiliation_string': 'From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.', 'institution_ids': ['https://openalex.org/I170201317']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5063630764', 'display_name': 'John C. Morris', 'orcid': 'https://orcid.org/0000-0001-9820-5618'}, 'institutions': [{'id': 'https://openalex.org/I170201317', 'display_name': 'University of Pittsburgh', 'ror': 'https://ror.org/01an3r305', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I170201317']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'J. C. Morris', 'raw_affiliation_strings': ['From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.'], 'affiliations': [{'raw_affiliation_string': 'From the Departments of Radiology (M.A.M., G.N.L., Y.I.S., C.S.D., S.Y.L., R.H.M.), Psychiatry (M.A.M., Y.I.S.), and Neurology (J.C.M.), Washington University School of Medicine, St. Louis, MO; and Departments of Psychiatry (W.E.K.), Radiology (C.A.M.), and Neurology (S.T.D.), University of Pittsburgh, PA.', 'institution_ids': ['https://openalex.org/I170201317']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 34.82, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 1030, 'citation_normalized_percentile': {'value': 0.999882, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '67', 'issue': '3', 'first_page': '446', 'last_page': '452'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10009', 'display_name': 'Dementia and Cognitive Impairment Research', 'score': 0.9984, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10009', 'display_name': 'Dementia and Cognitive Impairment Research', 'score': 0.9984, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10086', 'display_name': "Alzheimer's disease research and treatments", 'score': 0.998, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10241', 'display_name': 'Functional Brain Connectivity Studies', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/2805', 'display_name': 'Cognitive Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/pittsburgh-compound-b', 'display_name': 'Pittsburgh compound B', 'score': 0.81394464}], 'concepts': [{'id': 'https://openalex.org/C2781073650', 'wikidata': 'https://www.wikidata.org/wiki/Q4047010', 'display_name': 'Pittsburgh compound B', 'level': 4, 'score': 0.81394464}, {'id': 'https://openalex.org/C2781441883', 'wikidata': 'https://www.wikidata.org/wiki/Q1632835', 'display_name': 'Precuneus', 'level': 3, 'score': 0.7532877}, {'id': 'https://openalex.org/C502032728', 'wikidata': 'https://www.wikidata.org/wiki/Q11081', 'display_name': "Alzheimer's disease", 'level': 3, 'score': 0.5494784}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.4937974}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.49288774}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.4568681}, {'id': 'https://openalex.org/C2779483572', 'wikidata': 'https://www.wikidata.org/wiki/Q83030', 'display_name': 'Dementia', 'level': 3, 'score': 0.44102496}, {'id': 'https://openalex.org/C2779281540', 'wikidata': 'https://www.wikidata.org/wiki/Q5062122', 'display_name': 'Central nervous system disease', 'level': 2, 'score': 0.42836255}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.33713531}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.33160084}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.13832384}, {'id': 'https://openalex.org/C169900460', 'wikidata': 'https://www.wikidata.org/wiki/Q2200417', 'display_name': 'Cognition', 'level': 2, 'score': 0.1049079}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000544', 'descriptor_name': 'Alzheimer Disease', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': True}, {'descriptor_ui': 'D052160', 'descriptor_name': 'Benzothiazoles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D019275', 'descriptor_name': 'Radiopharmaceuticals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000369', 'descriptor_name': 'Aged, 80 and over', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000544', 'descriptor_name': 'Alzheimer Disease', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000544', 'descriptor_name': 'Alzheimer Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000814', 'descriptor_name': 'Aniline Compounds', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015415', 'descriptor_name': 'Biomarkers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002250', 'descriptor_name': 'Carbon Radioisotopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013844', 'descriptor_name': 'Thiazoles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1212/01.wnl.0000228230.26044.a4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S79704628', 'display_name': 'Neurology', 'issn_l': '0028-3878', 'issn': ['0028-3878', '1526-632X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16894106', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.44, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 42, 'referenced_works': ['https://openalex.org/W1771725737', 'https://openalex.org/W1835478781', 'https://openalex.org/W1847168837', 'https://openalex.org/W1963568158', 'https://openalex.org/W1969218941', 'https://openalex.org/W1972340735', 'https://openalex.org/W1975439178', 'https://openalex.org/W1980842500', 'https://openalex.org/W1986159971', 'https://openalex.org/W1990005524', 'https://openalex.org/W1990867963', 'https://openalex.org/W1991952617', 'https://openalex.org/W2017869626', 'https://openalex.org/W2024940817', 'https://openalex.org/W2046638602', 'https://openalex.org/W2047205872', 'https://openalex.org/W2051809205', 'https://openalex.org/W2052742260', 'https://openalex.org/W2054089714', 'https://openalex.org/W2054929374', 'https://openalex.org/W2055101973', 'https://openalex.org/W2063017390', 'https://openalex.org/W2064079339', 'https://openalex.org/W2072371192', 'https://openalex.org/W2082074713', 'https://openalex.org/W2084077702', 'https://openalex.org/W2084700554', 'https://openalex.org/W2112518510', 'https://openalex.org/W2113708991', 'https://openalex.org/W2115077024', 'https://openalex.org/W2119823987', 'https://openalex.org/W2121887890', 'https://openalex.org/W2149614271', 'https://openalex.org/W2150520466', 'https://openalex.org/W2158592797', 'https://openalex.org/W2159789463', 'https://openalex.org/W2162010696', 'https://openalex.org/W2167720733', 'https://openalex.org/W2416100884', 'https://openalex.org/W26683077', 'https://openalex.org/W4233356368', 'https://openalex.org/W4248875019'], 'related_works': ['https://openalex.org/W4312087008', 'https://openalex.org/W3021735676', 'https://openalex.org/W2098580427', 'https://openalex.org/W2076654666', 'https://openalex.org/W2070687658', 'https://openalex.org/W2062210296', 'https://openalex.org/W2041361760', 'https://openalex.org/W2035888582', 'https://openalex.org/W2027085658', 'https://openalex.org/W1985979329'], 'abstract_inverted_index': {'<b>Background:': [0], '</b>': [1, 71, 145, 208], 'Beta-amyloid': [2], '(Aβ)': [3], 'plaques': [4, 20], 'are': [5], 'the': [6, 39, 65, 102, 105, 123, 132, 137, 161, 182, 204, 238, 250], 'hallmark': [7], 'of': [8, 38, 67, 97, 125, 160, 188, 225, 240, 246, 249], 'Alzheimer': [9, 40, 228, 251], 'disease': [10, 229], '(AD).': [11], 'A': [12], 'PET': [13, 94], 'imaging': [14, 51, 219], 'tracer': [15], 'that': [16, 200, 216], 'binds': [17], 'to': [18, 44, 53, 64, 78, 89, 122, 236], 'Aβ': [19], 'in': [21, 33, 59, 212], 'vivo,': [22], 'N-methyl-[<sup>11</sup>C]2-(4′-methylaminophenyl)-6-hydroxybenzothiazole': [23], '(or': [24], '[<sup>11</sup>C]PIB': [25, 93, 194, 210, 217, 242], 'for': [26, 140, 223], '“Pittsburgh': [27], 'Compound-B”),': [28], 'has': [29], 'significantly': [30, 179], 'higher': [31], 'binding': [32, 57, 127, 211, 243], 'subjects': [34, 74, 155, 164, 192, 214], 'diagnosed': [35], 'with': [36, 84, 147], 'dementia': [37, 248], 'type': [41], '(DAT)': [42], 'compared': [43], 'nondemented': [45, 73, 154, 163, 191, 213], 'controls.': [46], 'The': [47], 'authors': [48], 'used': [49], 'this': [50], 'technique': [52], 'investigate': [54], 'whether': [55], 'abnormal': [56], 'occurs': [58], 'clinically': [60], 'normal': [61], 'individuals,': [62], 'prior': [63], 'development': [66], 'cognitive': [68], 'changes.': [69], '<b>Methods:': [70], 'Forty-one': [72], '(age': [75, 86], 'range': [76, 87], '20': [77], '86': [79, 90], 'years)': [80, 91], 'and': [81, 114, 136, 170, 198, 244], '10': [82], 'patients': [83], 'DAT': [85, 148, 183, 205], '66': [88], 'underwent': [92], 'scanning.': [95], 'Regions': [96], 'interest': [98], 'were': [99, 129, 177], 'drawn': [100], 'on': [101], 'MRI': [103], 'over': [104], 'cerebellar,': [106], 'prefrontal,': [107], 'lateral': [108], 'temporal,': [109], 'occipital,': [110], 'gyrus': [111], 'rectus,': [112], 'precuneus,': [113], 'striatal': [115], 'cortex.': [116], 'Binding': [117], 'potential': [118], 'values': [119, 152, 169, 173], '(BPs),': [120], 'proportional': [121], 'density': [124], '[<sup>11</sup>C]PIB-Aβ': [126], 'sites,': [128], 'calculated': [130], 'using': [131], 'Logan': [133], 'graphical': [134], 'analysis': [135], 'cerebellar': [138], 'cortex': [139], 'a': [141, 175, 226], 'reference': [142], 'tissue.': [143], '<b>Results:': [144], 'Patients': [146], 'had': [149, 165, 193], 'elevated': [150, 166, 241], 'BP': [151, 168, 172, 185], 'vs': [153], '(<i>p</i>': [156], '<': [157], '0.0001).': [158], 'Four': [159], '41': [162], 'cortical': [167], 'their': [171], 'as': [174], 'group': [176], 'not': [178], 'different': [180], 'from': [181, 203], 'subjects9': [184], 'values.': [186], 'Two': [187], 'these': [189], 'four': [190], 'uptake,': [195], 'both': [196], 'visually': [197], 'quantitatively,': [199], 'was': [201], 'indistinguishable': [202], 'subjects.': [206], '<b>Conclusions:': [207], 'Elevated': [209], 'suggests': [215], 'amyloid': [218], 'may': [220], 'be': [221, 234], 'sensitive': [222], 'detection': [224], 'preclinical': [227], 'state.': [230], 'Longitudinal': [231], 'studies': [232], 'will': [233], 'required': [235], 'determine': [237], 'association': [239], 'risk': [245], 'developing': [247], 'type.': [252]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1967642097', 'counts_by_year': [{'year': 2024, 'cited_by_count': 15}, {'year': 2023, 'cited_by_count': 24}, {'year': 2022, 'cited_by_count': 30}, {'year': 2021, 'cited_by_count': 29}, {'year': 2020, 'cited_by_count': 42}, {'year': 2019, 'cited_by_count': 32}, {'year': 2018, 'cited_by_count': 43}, {'year': 2017, 'cited_by_count': 59}, {'year': 2016, 'cited_by_count': 55}, {'year': 2015, 'cited_by_count': 72}, {'year': 2014, 'cited_by_count': 79}, {'year': 2013, 'cited_by_count': 84}, {'year': 2012, 'cited_by_count': 89}], 'updated_date': '2024-12-19T02:33:51.716588', 'created_date': '2016-06-24'}