Title: Nucleolipids: Natural Occurrence, Synthesis, Molecular Recognition, and Supramolecular Assemblies as Potential Precursors of Life and Bioorganic Materials
Abstract: Chemistry & BiodiversityVolume 2, Issue 8 p. 977-1063 Review Nucleolipids: Natural Occurrence, Synthesis, Molecular Recognition, and Supramolecular Assemblies as Potential Precursors of Life and Bioorganic Materials† Helmut Rosemeyer, Helmut Rosemeyer [email protected] [email protected] Katholieke Universiteit Leuven, Dept. Farmaceutische Wetenschappen, Afd. Medicinale Chemie, Minderbroederstraat 10, B-3000 Leuven Bioorganische Chemie, Institut für Chemie, Fachbereich Biologie/Chemie, Universität Osnabrück, Barbarastrasse 7, D-49069 Osnabrück (phone:++ 49-541-9692789; fax: ++ 49-541-9692370Search for more papers by this author Helmut Rosemeyer, Helmut Rosemeyer [email protected] [email protected] Katholieke Universiteit Leuven, Dept. Farmaceutische Wetenschappen, Afd. Medicinale Chemie, Minderbroederstraat 10, B-3000 Leuven Bioorganische Chemie, Institut für Chemie, Fachbereich Biologie/Chemie, Universität Osnabrück, Barbarastrasse 7, D-49069 Osnabrück (phone:++ 49-541-9692789; fax: ++ 49-541-9692370Search for more papers by this author First published: 23 August 2005 https://doi.org/10.1002/cbdv.200590082Citations: 90 † H. R. thanks the Francqui Foundation for a senior postdoctoral fellowship and Prof. Dr. Piet Herdewijn, Rega Institute, KU Leuven, for hosting a stay at the Department for Medicinale Chemie. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract Nucleolipids are hybrid molecules composed of a nucleobase, a nucleoside, a nucleotide or an oligonucleotide (either DNA or RNA), and a lipophilic moiety, which might be either simply a single- or double-chained alkyl (or alkenyl) moiety or a carbocyclic hydrocarbon such as cholesterol, a vitamin, or a bile acid. This review covers all aspects of nucleolipids, namely their natural occurrence, their synthesis, their molecular recognition, as well as aggregation behavior, either in aqueous or non-aqueous solution. Potential future aspects of nucleolipids in material sciences and for the elucidation of biochemical reactions in living cells are discussed. References 1 I. Ichinose, T. Kunitake, Oyo Butsuri 2003, 72, 304. 2 I. Ichinose, T. Kunitake, Chem. Rec. 2002, 2, 339. 3 I. Ichinose, Y. Hashimoto, T. Kunitake, Chemistry Lett. 2004, 33, 656. 4 T. Kunitake, Jiko Soshikika ni yoru Nano Materiaru no Sosei to Oyo 2003, 1– 33. 5 J. Smrt, S. Hynie, Collect. Czech. 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Publication Year: 2005
Publication Date: 2005-08-01
Language: en
Type: review
Indexed In: ['crossref', 'pubmed']
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