Title: The antral clear cell—a new cell type discovered in the pyloric-antral mucosa of the ferret
Abstract: The ultrastructure of the gastric, antral mucosa of fasted and fed ferrets was studied. The main cell type occupying the epithelial surface was the pylorus cell, a cell similar to the mucous cells in the fundus of the ferret, and in the antrum of other species. Typical argentaffin cells and, rarely, parietal cells were also observed. A granular, nonargentaffin cell was seen which had similar features to “endocrine” cells recently reported in the antrum by other investigators. A new cell type, the antral clear cell, was discovered, which occupied a basal location between pylorus cells at different depths of the pyloric crypt and gland. Resting on the basement membrane, the irregularly shaped cell was distinguished principally by an electron lucid cytoplasm and a paucity of intracellular organelles. The clear cell would appear to have an endocrine function, and may be a site of gastrin or gastric intrinsic factor formation.
Publication Year: 1969
Publication Date: 1969-12-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 14
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