Publication Information

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4070, 4134, 4191, 4197, 4260, 4285, 4316, 4389, 4394, 4472, 4555, 4603, 4614, 4632, 4653, 4861, 4869, 4876, 4890, 4909, 4914, 4923, 4926, 4930, 4939, 5102, 5116, 5209, 5234, 5251, 5260, 5266, 5281, 5299, 5308, 5315, 5329, 5337, 5575, 5582, 5593, 5603, 5614, 5619, 5652, 5671, 5709, 5746, 5842, 5851, 5862, 5866, 5869, 5872, 5955, 5987, 5990, 6041], 'gene': [3, 63, 70, 95, 201, 219, 250, 310, 317, 342, 448, 466, 879, 897, 921, 1491, 1504, 1963, 1980, 2064, 2144, 2343, 2779, 2950, 2975, 2990, 3008, 3017, 3131, 3152, 3256, 3309, 3363, 3465, 3485, 3614, 3724, 4059, 4402, 4408, 4467, 4611, 4642, 5239, 5261, 5509, 5545, 5598, 5843, 5870, 5936, 6046], 'regulatory': [4, 251, 880, 2930, 5224, 5262, 5947], 'mechanisms': [5, 252, 881], 'involved': [6, 253, 5669, 5698], 'in': [7, 28, 32, 84, 172, 185, 202, 224, 231, 240, 254, 275, 279, 331, 419, 432, 449, 471, 478, 487, 538, 613, 793, 803, 914, 1032, 1044, 1120, 1145, 1246, 1334, 1399, 1438, 1476, 1507, 1592, 1603, 1686, 1732, 1750, 1765, 1810, 2178, 2195, 2244, 2370, 2379, 2385, 2538, 2585, 2629, 2632, 2787, 2796, 2800, 2835, 2846, 2879, 2899, 2947, 3153, 3170, 3217, 3231, 3317, 3335, 3618, 3820, 3922, 3947, 3961, 4018, 4069, 4092, 4124, 4133, 4214, 4315, 4393, 4404, 4412, 4471, 4554, 4592, 4613, 4644, 4646, 4662, 4922, 5105, 5115, 5220, 5245, 5280, 5307, 5326, 5369, 5447, 5453, 5515, 5581, 5588, 5618, 5645, 5651, 5670, 5699, 5708, 5754, 5761, 5801, 5822, 5837, 5850, 5938, 5969], 'metabolic': [9, 256, 773, 916, 5642], 'control': [10, 242, 257, 489, 917, 1468, 1532, 2352, 2893, 3720, 5249, 5653, 5840, 5957], 'of': [11, 19, 47, 54, 117, 142, 169, 174, 197, 217, 243, 258, 266, 294, 301, 364, 389, 416, 421, 444, 464, 490, 583, 610, 782, 908, 918, 1036, 1085, 1092, 1103, 1328, 1337, 1384, 1395, 1413, 1469, 1500, 1533, 1717, 1723, 1737, 1743, 1755, 1759, 1902, 1919, 1958, 1969, 2005, 2044, 2073, 2096, 2121, 2140, 2156, 2208, 2211, 2235, 2274, 2280, 2328, 2336, 2345, 2423, 2429, 2436, 2444, 2483, 2617, 2661, 2679, 2684, 2770, 2862, 2882, 2889, 2908, 2987, 2998, 3040, 3095, 3141, 3149, 3168, 3180, 3194, 3204, 3238, 3252, 3278, 3294, 3332, 3339, 3387, 3422, 3430, 3438, 3448, 3458, 3481, 3492, 3506, 3509, 3528, 3558, 3570, 3578, 3669, 3678, 3721, 3825, 3941, 3950, 3959, 3964, 3975, 4006, 4023, 4042, 4047, 4074, 4089, 4096, 4106, 4131, 4136, 4193, 4273, 4288, 4355, 4391, 4396, 4474, 4543, 4557, 4575, 4580, 4588, 4616, 4634, 4639, 4652, 4838, 4878, 4886, 4892, 5089, 5236, 5292, 5301, 5317, 5331, 5363, 5444, 5561, 5578, 5596, 5605, 5633, 5649, 5654, 5692, 5711, 5749, 5820, 5841, 5853, 5868, 5954, 5958, 5989, 6043], 'cardiac': [12, 30, 74, 195, 232, 259, 277, 321, 442, 479, 528, 611, 883, 1508, 1808, 2283, 2788, 2847, 2963, 3171, 3213, 3619, 3925, 4397, 4919, 5267, 5361, 5974], 'fatty': [13, 40, 82, 88, 97, 212, 227, 260, 287, 329, 335, 344, 459, 474, 494, 503, 585, 617, 796, 884, 1038, 1047, 1094, 1106, 1338, 1379, 1385, 1486, 1516, 1535, 1676, 2785, 3249, 3315, 3341, 3474, 3512, 3615, 3685, 3718, 3735, 4398, 4462, 4866, 4879, 4897, 5094, 5108, 5213, 5243, 5252, 5273, 5296, 5310, 5333, 5440, 5551, 5590, 5611, 5629, 5807, 5855, 5931, 5960], 'acid': [14, 83, 98, 228, 261, 330, 345, 475, 495, 504, 618, 797, 885, 1048, 1095, 1339, 1380, 1386, 1536, 1725, 1728, 3475, 3616, 3629, 3686, 4399, 4463, 4898, 5095, 5109, 5214, 5274, 5311, 5630, 5808, 5961], 'oxidative': [15, 262, 1096, 1158, 4400], 'flux,': [16, 263], 'expression': [18, 124, 168, 196, 265, 371, 415, 443, 781, 922, 1499, 2363, 2448, 2486, 2570, 2780, 2907, 2951, 3813, 4403, 4409, 4468, 4587, 4612, 4643, 5088, 5240, 5300, 5362, 5443, 5510, 5577, 5691, 5937, 6047], 'muscle-type': [20, 267, 1236], 'carnitine': [21, 268, 497, 1139], 'palmitoyltransferase': [22, 269, 498, 1021, 1140], 'I': [23, 49, 62, 94, 171, 200, 270, 296, 309, 341, 418, 447, 1022, 1087, 1099, 1166, 1177, 1238, 1320, 1397, 1404, 1415, 1471, 1490, 1503, 1828, 1962, 1979, 2063, 2129, 2143, 2645, 2778, 2791, 2840, 2949, 2974, 2989, 3007, 3016, 3130, 3255, 3308, 3334, 3362, 3371, 3390, 3464, 3484, 3613, 3723, 3980, 4407, 4545, 4590, 4610, 4641, 5238, 5303, 5319, 5446, 5544, 5580, 5935, 6045], '(M-CPT': [24, 271, 1237], 'I)': [25, 272], 'was': [26, 76, 102, 179, 273, 323, 349, 426, 1588, 1652, 1681, 1694, 1699, 1703, 1748, 1777, 1803, 1898, 1964, 2027, 2048, 2056, 2135, 2285, 2331, 2493, 2528, 2572, 2583, 2612, 2656, 2707, 2754, 2896, 2920, 2993, 3146, 3173, 3208, 3280, 3287, 3402, 3411, 3424, 3572, 3587, 3713, 3919, 4012, 4126, 4141, 4202, 4322, 4410, 5662], 'characterized': [27, 274, 4411], 'primary': [29, 276, 2797], 'myocytes': [31, 233, 278, 480, 1549, 1809, 2284, 2799, 2810, 2848, 2964, 3172], 'culture': [33, 280, 1767, 1812, 2801, 5454], 'following': [34, 281, 2802, 4571, 5964], 'exposure': [35, 282, 2803, 2924], 'to': [36, 67, 104, 147, 283, 314, 351, 394, 540, 769, 1112, 1136, 1154, 1376, 1465, 1619, 1624, 1635, 1654, 1683, 1689, 1706, 1711, 1734, 1752, 1769, 1975, 2001, 2051, 2069, 2107, 2151, 2351, 2433, 2501, 2709, 2804, 2818, 2823, 2850, 2925, 2979, 3031, 3035, 3136, 3158, 3353, 3455, 3519, 3626, 3731, 3924, 3983, 4036, 4055, 4121, 4189, 4259, 4664, 4865, 4907, 4929, 5270, 5287, 5570, 5637, 5674, 5756, 5795], 'long-chain': [38, 81, 211, 285, 328, 458, 584, 1037, 1105, 1126, 1485, 1515, 1544, 2784, 3314, 3340, 5242, 5272, 5439, 5550, 5854, 5930], 'mono-unsaturated': [39, 286], 'acid,': [41, 288], 'oleate.': [42, 289], 'Oleate': [43, 290, 1680, 3188], 'induced': [44, 77, 291, 324, 3190, 3281, 3968, 3988, 4014, 4585, 5512], 'steady-state': [45, 292, 4541], 'levels': [46, 184, 293, 431, 2741, 2793, 2842, 4542], 'M-CPT': [48, 61, 93, 170, 199, 295, 308, 340, 417, 446, 1403, 1470, 1489, 1502, 1827, 1961, 1978, 2062, 2128, 2142, 2644, 2777, 2790, 2839, 2948, 2973, 2988, 3006, 3015, 3129, 3254, 3307, 3333, 3361, 3370, 3389, 3463, 3483, 3612, 3722, 4406, 4544, 4589, 4609, 4640, 5237, 5302, 5543, 5579, 5845, 5934, 6044], 'mRNA': [50, 297, 2740, 2792, 2841, 2910, 4546, 4591], '4.5-fold.': [51, 298], 'The': [52, 92, 167, 299, 339, 414, 878, 1083, 1401, 1701, 1720, 1740, 1914, 1955, 1997, 2084, 2127, 2197, 2509, 2567, 2643, 2887, 3013, 3092, 3128, 3164, 3201, 3399, 3418, 3503, 3533, 3566, 3915, 3938, 3973, 4225, 4319, 4567, 4648, 4830, 5360, 5537, 5559, 5647, 5690, 5818], 'transcription': [53, 216, 300, 463, 911, 3103, 3251, 3310, 3677, 3970, 3990, 4005, 5546, 5595, 5667], 'a': [55, 68, 85, 105, 137, 189, 218, 221, 236, 302, 315, 332, 352, 384, 436, 465, 468, 483, 767, 1040, 1104, 1181, 1528, 1713, 1735, 1753, 1825, 1830, 1848, 1857, 1882, 1970, 1987, 2162, 2167, 2212, 2245, 2338, 2341, 2401, 2446, 2451, 2662, 2687, 2710, 2729, 2892, 2915, 2968, 2980, 2999, 3154, 3318, 3349, 3473, 3499, 3538, 3543, 3714, 3810, 3935, 4037, 4056, 4093, 4117, 4153, 4163, 4205, 4229, 4270, 4297, 4326, 4385, 4572, 4577, 4901, 5231, 5276, 5332, 5555, 5571, 5641, 5666, 5847, 5882, 5952], 'plasmid': [56, 303, 2082, 2246, 2330, 2339, 2425, 2969, 3157], 'construct': [57, 304, 2108, 3541, 4010], 'containing': [58, 305, 1608, 1660, 2166, 2228, 2340, 2382, 2450, 2712, 2970, 3003, 3220, 3369, 3542], 'human': [60, 307, 1858, 1960, 2061, 2365, 2675, 2972, 3005, 3014, 3360], 'promoter': [64, 96, 311, 343, 2130, 2243, 2976, 3364, 3459, 3486, 4053, 5867], 'region': [65, 312, 1957, 1998, 2066, 2977, 3133, 3357, 3467, 3488], 'fused': [66, 313, 2978, 4054], 'luciferase': [69, 316, 2981, 3151, 4057], 'reporter': [71, 318, 2329, 2424, 2982, 3156, 3367, 3441, 4058], 'transfected': [72, 319, 2437, 2966], 'into': [73, 320, 1128, 2078, 2187, 2231, 2621, 4128, 5857], 'myocytes,': [75, 322, 1509, 2789, 3926], 'over': [78, 325], '20-fold': [79, 326], 'by': [80, 327, 1138, 1172, 1324, 1514, 1543, 1865, 1879, 1966, 2058, 2093, 2137, 2206, 2270, 2520, 2530, 2575, 2614, 2658, 2726, 2735, 2744, 2783, 2923, 2995, 3210, 3284, 3290, 3313, 3498, 3589, 3734, 3801, 4015, 4212, 4324, 5241, 5250, 5513, 5549, 6048], 'concentration-dependent': [86, 333, 3319], 'and': [87, 112, 234, 334, 359, 481, 537, 542, 615, 623, 802, 806, 906, 1235, 1250, 1440, 1590, 1617, 1673, 1726, 1856, 1916, 2089, 2110, 2116, 2191, 2202, 2220, 2377, 2426, 2497, 2525, 2588, 2626, 2715, 2717, 2873, 3011, 3025, 3033, 3098, 3268, 3286, 3320, 3382, 3407, 3470, 3606, 3683, 3816, 4067, 4072, 4216, 4235, 4245, 4255, 4294, 4311, 4380, 4448, 4460, 4661, 4667, 4840, 4921, 5114, 5118, 5304, 5320, 5371, 5449, 5517, 5566, 5608, 5703, 5814, 5966, 5976, 6001], 'acyl-chain': [89, 336, 5564], 'length-specific': [90, 337, 3323, 5565], 'manner.': [91, 338, 3324], 'response': [99, 139, 346, 386, 505, 539, 3207, 3401, 3451, 3476, 3586, 3617, 3930, 4155, 4377, 4663, 5557, 5673, 5755, 5884], 'element': [100, 140, 347, 387, 3514, 3622, 5885], '(FARE-1)': [101, 348, 4275], 'localized': [103, 350], 'hexameric': [106, 353, 3495, 3556], 'repeat': [107, 354, 3496], 'sequence': [108, 355, 2043, 2272, 2650, 3479, 3505, 3561], 'located': [109, 356, 1119, 3603], 'between': [110, 357, 2738, 3468, 3604], '775': [111, 358], '763': [113, 360], 'base': [114, 361, 516, 1983, 2118, 2153, 3037, 3138], 'pairs': [115, 362, 2119, 2154, 3038, 3139], 'upstream': [116, 363, 2072, 2234, 3039, 3148, 3386, 4046], 'initiator': [119, 366], 'codon.': [120, 367], 'Cotransfection': [121, 368, 3958, 4061], 'experiments': [122, 369, 2359, 2667, 2959, 3216, 3262, 4267], 'with': [123, 161, 370, 408, 795, 1643, 1893, 2333, 2360, 2390, 2670, 2853, 2902, 2962, 2967, 3241, 3272, 3329, 3348, 3404, 3413, 3537, 3809, 3986, 4065, 4099, 4104, 4165, 4196, 4204, 4232, 4238, 4269, 4292, 4450, 4562, 4874, 5107, 5328, 5602, 5803, 5861], 'vectors': [125, 372], 'for': [126, 177, 238, 373, 424, 485, 1405, 1530, 1908, 1992, 2169, 2353, 2628, 2719, 2832, 2894, 3396, 3523, 3546, 3610, 3644, 3716, 3934, 4374, 4415, 4904, 5211, 5233, 5265, 5714, 5806, 5835, 5986, 5998, 6004], 'peroxisome': [128, 375, 507, 1520, 5675, 5757], 'proliferator-activated': [129, 376, 508, 1521], 'receptor': [130, 165, 377, 412, 509, 520, 1522, 2582, 3531, 3712], 'α': [131, 378, 1523], '(PPARα)': [132, 379], 'demonstrated': [133, 156, 380, 403, 778, 1163, 4539, 5928], 'that': [134, 157, 210, 381, 404, 457, 779, 1164, 1412, 1467, 1484, 1498, 2040, 2928, 3027, 3179, 3306, 3429, 3437, 3445, 3577, 3600, 3637, 3673, 3710, 4122, 4284, 4309, 4329, 4458, 4540, 5087, 5295, 5542, 5627, 5865, 5914, 5929, 5944], 'FARE-1': [135, 160, 382, 407, 2646, 3798, 4031, 4043, 4132, 4151, 4207, 4226, 4383, 5562], 'is': [136, 383, 577, 787, 1088, 1243, 1322, 1374, 1390, 1407, 1442, 1505, 2651, 2781, 3257, 3311, 3452, 3608, 3799, 3931, 4469, 4656, 5099, 5216, 5324, 5511, 5547, 5563, 5600, 5658, 5706, 5759, 5798, 5949, 5967], 'PPARα': [138, 158, 178, 190, 204, 239, 385, 405, 425, 437, 451, 486, 1909, 1922, 2362, 2453, 2491, 2619, 2676, 3674, 3727, 3811, 3830, 4034, 4090, 4139, 4154, 4157, 4217, 4233, 4254, 4293, 4310, 4332, 4376, 4379, 4392, 4416, 4635, 5556, 5650, 5661, 5693, 5715, 5751, 5797, 5821, 5836, 5883, 5915], 'capable': [141, 388], 'conferring': [143, 390], 'oleate-mediated': [144, 391], 'transcriptional': [145, 392, 791, 1512, 2955, 3166, 3192, 3236, 3420, 3568, 3939, 5103, 5223, 5248, 5839, 5946], 'activation': [146, 393, 3998, 4095, 4111, 5560], 'homologous': [148, 395], 'or': [149, 396, 1178, 1239, 1813, 1878, 1910, 2480, 2686, 2704, 2828, 3223, 3631, 3818, 3823, 3827, 3952, 3977, 4021, 4076, 4108, 4276, 4349], 'heterologous': [150, 397, 2198, 4038, 5572], 'promoters.': [151, 398], 'Electrophoretic': [152, 399], 'mobility': [153, 400, 524, 4290, 4362], 'shift': [154, 401, 525], 'assays': [155, 402], 'bound': [159, 406], 'retinoid': [163, 410, 518], 'X': [164, 411, 519], 'α.': [166, 413], 'hearts': [173, 420, 4556, 4615], 'mice': [175, 422, 1906, 1920, 4413, 4476, 4560, 4594, 4618, 5372, 5712, 5763], 'null': [176, 205, 423, 452, 1907, 4414, 5713], 'approximately': [180, 427, 1408, 3425], '50%': [181, 428, 1636, 3426], 'lower': [182, 429, 1410, 3427, 4549], 'than': [183, 430, 1411, 3178, 3428, 3436, 3576, 3945, 3993], 'wild-type': [186, 433, 1912], 'controls.': [187, 434, 1913], 'Moreover,': [188, 435, 5574], 'activator': [191, 438, 3967, 4579, 4605, 4638], 'did': [192, 439, 4358, 4606], 'not': [193, 440, 888, 2885, 2897, 2921, 2933, 3186, 3288, 3453, 3573, 3581, 4013, 4359, 4607, 5826], 'induce': [194, 441, 4608, 5298, 5442], 'mice.': [206, 453], 'These': [207, 454, 1461, 3325, 3597, 4629, 5257, 5623], 'results': [208, 455, 1526, 3326, 3598, 3668, 4149, 4630, 5258, 5538, 5624, 5830, 5912], 'demonstrate': [209, 456, 1497, 4370, 5541, 5831], 'acids': [213, 460, 586, 1487, 1517, 2786, 3316, 3736, 4867, 4880, 5244, 5297, 5441, 5552, 5591, 5612, 5856, 5932], 'regulate': [214, 461, 1488, 5933], 'encoding': [220, 467, 784, 898, 1851, 2865, 2911, 2938, 3680, 5092, 5696, 5844, 5871], 'pivotal': [222, 469, 5848], 'enzyme': [223, 470, 920, 4401, 4466, 5508, 5849, 5877], 'mitochondrial': [226, 473, 581, 1034, 1123, 1130, 1540, 2867, 2918, 2939, 3337, 3682, 4459, 5093, 5271, 5704, 5874], 'uptake': [229, 476, 5852], 'pathway': [230, 477, 1050, 1336, 5644], 'define': [235, 482, 4150], 'role': [237, 484, 3331, 4633, 5648, 5819], 'myocardial': [244, 491, 554, 575, 1534, 4586, 5212, 5282, 5917, 5959], 'lipid': [245, 492, 5283, 5656, 5922], 'metabolism.': [246, 493, 5923], 'oxidation': [496, 619, 1381, 3687, 4877, 4899, 5215, 5809], 'muscle': [499], 'type': [500, 502], 'liver': [501, 1439, 4473, 5516, 5710], 'element-1': [506], 'bovine': [510, 2824], 'serum': [511, 1615, 2825], 'albumin': [512, 2826], 'polymerase': [513, 2032], 'chain': [514, 3259, 3322], 'reaction': [515, 1031], 'pair(s)': [517], 'thymidine': [521, 2240], 'kinase': [522, 2241], 'electrophoretic': [523], 'assay.': [526], 'Mammalian': [527], 'energy': [529, 576, 772, 4649, 4834, 4871, 4905, 4932, 4941, 5616], 'substrate': [530, 555, 1546, 4650, 4933, 4942, 5617], 'utilization': [531, 625, 798, 886, 1049, 1537, 4934, 5110, 5284, 5312, 5962], 'rates': [532, 621, 799, 5111], 'are': [533, 1134, 3327, 4547, 5635], 'regulated': [534, 1042, 1506, 2782, 5100, 5278], 'during': [535, 800, 1382, 4659, 5112, 5336], 'development': [536, 609, 801, 4660, 5113], 'physiologic': [541, 4666, 4910], 'pathophysiologic': [543, 4668, 5970], 'stimuli.': [544], 'During': [545, 607, 4918], 'fetal': [547, 771, 1613, 2392, 4831, 4931], 'period,': [548], 'glucose': [549, 624, 4839, 4937], 'serves': [550], 'as': [551, 1168, 1556, 1779, 2287, 2548, 2591, 2756, 3101, 3627, 3641, 4152, 4162, 4372, 4384, 4636, 4868, 4938, 5613, 5665, 5811, 5918, 5920, 5951, 5973], 'chief': [553, 4870, 4940, 5615], '(1Neely': [556, 2010, 4842], 'J.R.': [557, 2011, 4843], 'Rovetto': [558, 2012, 4844], 'M.J.': [559, 2013, 4845], 'Oram': [560, 2014, 4846], 'J.F.': [561, 2015, 4847], 'Prog.': [562, 2016, 4848], 'Cardiovasc.': [563, 699, 2017, 4762, 4849, 5015], 'Dis.': [564, 2018, 4850], '1972;': [565, 2019, 4851], '15:': [566, 1948, 2020, 4441, 4499, 4852, 5738, 5786], '289-329Crossref': [567, 2021, 4853], 'PubMed': [568, 637, 650, 676, 704, 729, 743, 762, 823, 850, 873, 945, 968, 998, 1017, 1065, 1078, 1205, 1230, 1267, 1288, 1314, 1355, 1368, 1429, 1580, 1798, 1950, 2022, 2263, 2311, 2475, 2564, 2607, 3065, 3087, 3123, 3661, 3703, 3769, 3790, 3852, 3889, 3910, 4181, 4344, 4443, 4501, 4531, 4700, 4713, 4739, 4767, 4792, 4806, 4825, 4854, 4953, 4966, 4992, 5020, 5045, 5059, 5078, 5135, 5162, 5185, 5205, 5395, 5417, 5435, 5478, 5501, 5534, 5685, 5740, 5788, 5906, 6035], 'Scopus': [569, 603, 638, 651, 677, 705, 730, 744, 763, 824, 851, 874, 946, 969, 999, 1066, 1079, 1231, 1268, 1289, 1315, 1356, 1369, 1430, 1457, 1581, 1951, 2023, 2312, 2476, 3066, 3088, 3124, 3662, 3704, 3770, 3791, 3853, 3890, 3911, 4182, 4345, 4444, 4502, 4532, 4686, 4701, 4714, 4740, 4768, 4793, 4807, 4826, 4855, 4954, 4967, 4993, 5021, 5046, 5060, 5079, 5136, 5163, 5186, 5356, 5396, 5479, 5502, 5686, 5741, 5789, 5907, 6036], '(380)': [570, 2024, 4856], 'Google': [571, 605, 640, 653, 679, 707, 732, 746, 765, 826, 853, 876, 948, 971, 1001, 1018, 1068, 1081, 1206, 1233, 1270, 1291, 1317, 1358, 1371, 1432, 1459, 1583, 1799, 1846, 1953, 2025, 2264, 2314, 2478, 2565, 2608, 3068, 3090, 3126, 3664, 3706, 3772, 3793, 3855, 3892, 3913, 4184, 4347, 4446, 4504, 4534, 4688, 4703, 4716, 4742, 4770, 4795, 4809, 4828, 4857, 4956, 4969, 4995, 5023, 5048, 5062, 5081, 5138, 5165, 5188, 5206, 5358, 5398, 5418, 5436, 5481, 5504, 5535, 5688, 5743, 5791, 5909, 6038], 'Scholar).': [572, 606, 877, 1019, 1082, 1318, 1372, 1460, 1584, 1800, 1954, 2265, 2420, 2566, 2609, 3091, 3127, 3665, 3794, 3914, 4185, 4535, 4829, 4858, 5082, 5207, 5359, 5437, 5505, 5536, 5689, 5744, 5792], 'Following': [573, 4859], 'birth,': [574, 4860], 'produced': [578, 4218], 'primarily': [579, 4835], 'via': [580, 1157, 1478, 1518, 5222, 5553], 'β-oxidation': [582, 1149, 2868, 4464, 5096], '(2Bing': [587, 4670, 5340], 'R.J.': [588, 4671, 5341], 'Harvey': [589, 4672, 5342], 'Lect.': [590, 4673, 5343], '1955;': [591, 4674, 5344], '50:': [592, 741, 4675, 4804, 5057, 5345], '27-70Google': [593, 4676, 5346], 'Scholar,': [594, 641, 654, 661, 680, 708, 733, 747, 827, 854, 949, 972, 1002, 1069, 1207, 1271, 1292, 1359, 3069, 3773, 3856, 3893, 4505, 4677, 4689, 4704, 4717, 4724, 4743, 4771, 4796, 4810, 4957, 4970, 4977, 4996, 5024, 5049, 5063, 5139, 5166, 5189, 5347, 5399, 5419, 5482], '3Taegtmeyer': [595, 4678, 5348], 'H.': [596, 643, 860, 955, 1261, 1281, 1941, 3081, 3117, 4434, 4492, 4679, 4706, 4959, 5172, 5349, 5731, 5779], 'Curr.': [597, 4680, 5350], 'Prob.': [598, 4681, 5351], 'Cardiol.': [599, 755, 4682, 4818, 5071, 5352], '1994;': [600, 756, 1014, 2260, 2472, 2561, 2604, 3849, 4683, 4819, 5072, 5353, 5903], '19:': [601, 4684, 5354], '57-116Crossref': [602, 4685, 5355], '(336)': [604, 4687, 5357], 'hypertrophy': [612, 4920, 5975], 'rodents': [614], 'humans,': [616], '(FAO)1': [620], 'decrease': [622], 'increases': [626, 3240], '(4Bishop': [627, 4943], 'S.P.': [628, 4691, 4944], 'Altschuld': [629, 4692, 4945], 'R.A.': [630, 1211, 4174, 4693, 4946], 'Am.': [631, 1840, 4694, 4947], 'J.': [632, 656, 714, 752, 987, 1196, 1303, 1425, 1449, 1789, 1841, 1931, 3050, 3777, 3897, 4424, 4482, 4520, 4695, 4719, 4777, 4815, 4948, 4972, 5030, 5068, 5196, 5408, 5426, 5467, 5492, 5496, 5525, 5721, 5769, 6017, 6024], 'Physiol.': [633, 1842, 4696, 4949], '1970;': [634, 4697, 4950], '218:': [635, 4698, 4951], '153-159Crossref': [636, 4699, 4952], '(185)': [639, 4702, 4955], '5Taegtmeyer': [642, 4705, 4958], 'Overturf': [644, 4707, 4960], 'M.L.': [645, 4708, 4961], 'Hypertension.': [646, 4709, 4962], '1988;': [647, 4710, 4963], '11:': [648, 4711, 4964], '416-426Crossref': [649, 4712, 4965], '(201)': [652, 4715, 4968], '6Scheuer': [655, 4718, 4971], 'Circulation.': [657, 672, 725, 819, 4720, 4735, 4788, 4973, 4988, 5041, 5131], '1993;': [658, 673, 1199, 4721, 4736, 4974, 4989, 5199, 5429, 5528], '87:': [659, 674, 4722, 4737, 4975, 4990], 'VII54-VII57Google': [660, 4723, 4976], '7Moalic': [662, 4725, 4978], 'J.-M.': [663, 4726, 4979], 'Charlemagne': [664, 4727, 4980], 'D.': [665, 682, 716, 858, 953, 4728, 4745, 4779, 4981, 4998, 5032, 5170, 6023], 'Mansier': [666, 4729, 4982], 'P.': [667, 3056, 3750, 3870, 4730, 4983, 6019], 'Chevalier': [668, 4731, 4984], 'B.': [669, 671, 1213, 1445, 1451, 3650, 3692, 4732, 4734, 4985, 4987, 5193, 5423, 5522], 'Swynghedauw': [670, 4733, 4986], 'IV21-IV26Crossref': [675, 4738, 4991], '(54)': [678, 4741, 4994], '8Takeyama': [681, 4744, 4997], 'Kagaya': [683, 4746, 4999], 'Y.': [684, 686, 1257, 1275, 1279, 3073, 3075, 3077, 3109, 3111, 3113, 4747, 4749, 5000, 5002], 'Yamane': [685, 4748, 5001], 'Shiba': [687, 4750, 5003], 'N.': [688, 696, 1255, 1273, 3071, 3107, 4511, 4751, 4759, 5004, 5012], 'Chida': [689, 4752, 5005], 'M.': [690, 1056, 1346, 4336, 4753, 5006, 5191, 5421, 5466, 5520], 'Takahashi': [691, 4754, 5007], 'T.': [692, 694, 698, 1006, 1929, 2252, 2456, 2460, 2553, 2596, 3648, 3690, 3833, 3837, 4334, 4422, 4480, 4507, 4513, 4517, 4755, 4757, 4761, 5008, 5010, 5014, 5719, 5767, 5887, 5891], 'Ido': [693, 4756, 5009], 'Ishide': [695, 4758, 5011], 'Takishima': [697, 4760, 5013], 'Res.': [700, 739, 4763, 4802, 5016, 5055], '1995;': [701, 726, 990, 1075, 1227, 1264, 1365, 1947, 4440, 4498, 4764, 4789, 5017, 5042, 5737, 5785], '29:': [702, 4765, 5018], '763-767Crossref': [703, 4766, 5019], '(39)': [706, 4769, 5022], '9Massie': [709, 4772, 5025], 'B.M.': [710, 3775, 3895, 4773, 5026], 'Schaefer': [711, 4774, 5027], 'S.': [712, 814, 833, 868, 928, 963, 976, 1225, 1563, 2294, 2458, 2470, 3764, 3785, 3835, 3847, 3884, 3905, 4775, 5028, 5126, 5145, 5180, 5378, 5458, 5680, 5889, 5901], 'Garcia': [713, 4776, 5029], 'McKirnan': [715, 4778, 5031], 'Schwartz': [717, 4780, 5033], 'G.G.': [718, 4781, 5034], 'Wisneski': [719, 4782, 5035], 'J.A.': [720, 1447, 4783, 5036], 'Weiner': [721, 4784, 5037], 'M.W.': [722, 4785, 5038], 'White': [723, 4786, 5039], 'F.C.': [724, 4787, 5040], '91:': [727, 2473, 3850, 4790, 5043, 5904], '1814-1823Crossref': [728, 4791, 5044], '(80)': [731, 4794, 5047], '10Alpert': [734, 4797, 5050], 'N.R.': [735, 4798, 5051], 'Mulieri': [736, 4799, 5052], 'L.A.': [737, 4800, 5053], 'Circ.': [738, 4801, 5054], '1982;': [740, 4803, 5056], '491-500Crossref': [742, 4805, 5058], '(181)': [745, 4808, 5061], '11Christe': [748, 4811, 5064], 'M.E.': [749, 978, 1004, 2250, 2551, 2594, 4812, 5065], 'Rodgers': [750, 4813, 5066], 'R.L.': [751, 4814, 5067], 'Mol.': [753, 844, 939, 1011, 1574, 1944, 2257, 2305, 2558, 2601, 4437, 4495, 4816, 5069, 5156, 5389, 5734, 5782], 'Cell.': [754, 845, 940, 1012, 1575, 1945, 2258, 2306, 2559, 2602, 4438, 4496, 4817, 5070, 5157, 5390, 5735, 5783], '26:': [757, 4820, 5073], '1371-1375Abstract': [758, 4821, 5074], 'Full': [759, 993, 995, 1202, 1309, 1311, 1795, 4526, 4528, 4822, 5075, 5202, 5414, 5432, 5473, 5475, 5531, 6030, 6032], 'Text': [760, 994, 996, 1203, 1310, 1312, 1796, 4527, 4529, 4823, 5076, 5203, 5415, 5433, 5474, 5476, 5532, 6031, 6033], 'PDF': [761, 997, 1204, 1313, 1797, 4530, 4824, 5077, 5204, 5416, 5434, 5477, 5533, 6034], '(167)': [764, 4827, 5080], 'Scholar):': [766], 'reversion': [768], 'program.': [774], 'Recent': [775, 1160], 'studies': [776, 893, 1161, 3634, 3671, 4062, 4307, 4455, 4538, 4568, 5084], 'have': [777, 887, 902, 1162, 1463, 1923, 3635, 4456, 5085, 5927], 'genes': [783, 2864, 2937, 3679, 5091, 5695], 'FAO': [785, 919, 5268, 5321, 5507, 5705, 5875], 'enzymes': [786, 2870, 3688, 5098, 5306, 5323, 5365, 5697, 5753], 'regulated,': [788], 'at': [789, 1474, 1510, 1538, 2173, 2373, 2722, 2953, 3292, 4889, 5101, 5218], 'level,': [792, 1513, 2956], 'parallel': [794, 5106, 5327], 'hypertrophied': [805, 5117], 'failing': [807, 4924, 5119], 'heart': [808, 1441, 4645, 4655, 4832, 4863, 5120, 5518, 5585, 5939], '(12Sack': [809, 5121], 'M.N.': [810, 856, 951, 5122, 5168], 'Rader': [811, 830, 925, 1560, 2291, 5123, 5142, 5375], 'T.A.': [812, 831, 926, 1561, 2292, 5124, 5143, 5376], 'Park': [813, 5125], 'McCune': [815, 5127], 'S.A.': [816, 3738, 3742, 3858, 3862, 4168, 5128], 'Kelly': [817, 842, 861, 937, 956, 985, 1009, 1572, 1838, 2255, 2303, 2463, 2556, 2599, 3840, 5129, 5154, 5173, 5387, 5894, 6002], 'D.P.': [818, 843, 862, 938, 957, 986, 1010, 1573, 1782, 1839, 2256, 2304, 2464, 2557, 2600, 3841, 5130, 5155, 5174, 5388, 5401, 5895], '1996;': [820, 847, 942, 1285, 1306, 1577, 2308, 3658, 3700, 5132, 5159, 5392, 5498], '94:': [821, 871, 966, 3767, 3788, 3887, 3908, 5133, 5183], '2837-2842Crossref': [822, 5134], '(547)': [825, 5137], '13Disch': [828, 5140], 'D.L.': [829, 924, 1559, 1937, 2290, 4430, 4488, 5141, 5374, 5727, 5775], 'Cresci': [832, 927, 975, 1562, 2293, 2457, 3834, 5144, 5377, 5888], 'Leone': [834, 929, 1564, 2295, 5146, 5379], 'T.C.': [835, 930, 974, 1565, 2296, 5147, 5380], 'Barger': [836, 931, 1566, 2297, 5148, 5381], 'P.M.': [837, 932, 1567, 1939, 2298, 4432, 4490, 5149, 5382, 5729, 5777], 'Vega': [838, 933, 1568, 2299, 5150, 5383], 'R.': [839, 934, 1569, 1786, 2300, 5151, 5384, 5405], 'Wood': [840, 935, 1570, 2301, 5152, 5385], 'P.A.': [841, 936, 1571, 2302, 5153, 5386], 'Biol.': [846, 941, 988, 1013, 1197, 1304, 1576, 1790, 1946, 2259, 2307, 2560, 2603, 3657, 3699, 4439, 4497, 4521, 5158, 5197, 5391, 5409, 5427, 5468, 5526, 5736, 5784, 6025], '16:': [848, 943, 1578, 2309, 5160, 5393], '4043-4051Crossref': [849, 944, 1579, 2310, 5161, 5394], '(67)': [852, 947, 1582, 2313, 5164, 5397], '14Sack': [855, 950, 5167], 'Disch': [857, 952, 5169], 'Rockman': [859, 954, 5171], 'Proc.': [863, 958, 1220, 2465, 3759, 3780, 3842, 3879, 3900, 5175, 5896], 'Natl.': [864, 959, 1221, 2466, 3760, 3781, 3843, 3880, 3901, 5176, 5897], 'Acad.': [865, 960, 1222, 2467, 3761, 3782, 3844, 3881, 3902, 5177, 5898], 'Sci.': [866, 961, 1223, 2468, 3762, 3783, 3845, 3882, 3903, 5178, 5899], 'U.': [867, 962, 1224, 2469, 3763, 3784, 3846, 3883, 3904, 5179, 5900], 'A.': [869, 964, 1226, 1259, 1277, 2471, 3079, 3115, 3765, 3786, 3848, 3885, 3906, 5181, 5902], '1997;': [870, 965, 1843, 3062, 3084, 3120, 3766, 3787, 3886, 3907, 5182, 5470], '6438-6443Crossref': [872, 967, 5184], '(177)': [875, 970, 5187], 'governing': [882], 'been': [889, 1924, 3729, 5827], 'delineated;': [890], 'however,': [891], 'recent': [892], 'focused': [894], 'on': [895, 1638, 2728, 4913, 5610], 'medium-chain': [899, 2874, 5878], 'acyl-CoA': [900, 2875, 5879], 'dehydrogenase': [901, 2876, 5880], 'implicated': [903], 'nuclear': [904, 2916, 2936, 3530, 5090, 5254], 'receptors': [905], 'members': [907, 3527], 'Sp': [910], 'factor': [912, 5668], 'family': [913], '(13Disch': [923, 1558, 2289, 5373], '15Leone': [973], 'Carter': [977], 'Zhang': [979, 1212], 'Z.': [980], 'Lala': [981], 'D.S.': [982], 'Strauss': [983, 1787, 5406], 'A.W.': [984, 1788, 5407], 'Chem.': [989, 1198, 1305, 1791, 4522, 5198, 5410, 5428, 5469, 5527, 6026], '270:': [991], '16308-16314Abstract': [992], '(40)': [1000], '16Carter': [1003], 'Gulick': [1005, 2251, 2552, 2578, 2595, 5995], 'Moore': [1007, 2253, 2461, 2554, 2597, 3838, 5892], 'D.D.': [1008, 2254, 2462, 2555, 2598, 3839, 5893], '14:': [1015, 2261, 2562, 2605], '4360-4372Crossref': [1016, 2262, 2563, 2606], 'Carnitine': [1020], '(CPT': [1023, 1142], 'I;': [1024], 'palmitoyl-CoA:l-carnitine': [1025], 'O-palmitoyltransferase;': [1026], 'EC2.3.1.21)': [1027], 'catalyzes': [1028, 1100], 'initial': [1030, 1917], 'import': [1035, 1541, 3338], 'acids,': [1039], 'tightly': [1041, 4657], 'step': [1043, 5279], 'cellular': [1046, 1093, 5309], '(17McGarry': [1051, 1341], 'J.D.': [1052, 1071, 1195, 1219, 1302, 1342, 1361, 1417, 5464, 5490], 'Woeltje': [1053, 1343], 'K.F.': [1054, 1344], 'Kuwajima': [1055, 1345], 'Foster': [1057, 1192, 1216, 1299, 1347], 'D.W.': [1058, 1193, 1217, 1300, 1348, 1423], 'Diabetes': [1059, 1349], 'Metab.': [1060, 1350], 'Rev.': [1061, 1351, 3654, 3696], '1989;': [1062, 1352, 1792, 5411], '5:': [1063, 1353], '271-284Crossref': [1064, 1354], '(292)': [1067, 1357], '18McGarry': [1070, 1360], 'Biochem.': [1072, 1362, 1424, 1453, 5497], 'Soc.': [1073, 1363], 'Trans.': [1074, 1364], '23:': [1076, 1366], '321-324Crossref': [1077, 1367], '(101)': [1080, 1370], 'activity': [1084, 1321, 1398, 1472, 2527, 3167, 3193, 3237, 3277, 3421, 3569, 3940, 4098, 5316], 'CPT': [1086, 1098, 1165, 1179, 1240, 1319, 1396, 3979, 5318, 5445], 'an': [1089, 1869, 2380, 2539, 3449, 3493, 3965, 4100, 4277, 4350, 4637], 'important': [1090, 5833], 'determinant': [1091], 'flux.': [1097], 'transfer': [1102], 'acyl': [1107, 1545, 3258, 3321], 'group': [1108], 'from': [1109, 1552, 1805, 1900, 1989, 1999, 2067, 2149, 2695, 2812, 3029, 3375], 'coenzyme': [1110], 'A': [1111, 1114, 2412, 2750, 2984, 4247], 'carnitine.': [1113], 'specific': [1115, 4274, 4298], 'translocase': [1116], '(carnitine-acylcarnitine': [1117], 'carrier)': [1118], 'inner': [1122], 'membrane': [1124], 'delivers': [1125], 'acylcarnitines': [1127], 'matrix': [1131], 'where': [1132], 'they': [1133], 're-esterified': [1135], 'acyl-thioesters': [1137], 'II': [1141, 3526], 'II).': [1143], 'Acyl-thioesters': [1144], 'mitochondria': [1147], 'undergo': [1148], 'generating': [1150], 'reducing': [1151], 'equivalents': [1152], 'used': [1153, 1823, 2106, 2627, 3395], 'produce': [1155], 'ATP': [1156, 4883], 'phosphorylation.': [1159], 'exists': [1167], 'two': [1169, 2209, 3021, 4040], 'isoforms': [1170], 'encoded': [1171, 2917], 'separate': [1173], 'genes:': [1174], 'liver-type': [1175], '(L-CPT': [1176], 'IA),': [1180], 'hepatic-enriched,': [1182], 'ubiquitously': [1183], 'expressed': [1184, 1244, 5799], 'protein': [1185], '(19Esser': [1186], 'V.': [1187, 1215, 1294, 5462, 5488], 'Britton': [1188], 'C.H.': [1189, 1209], 'Weis': [1190], 'B.C.': [1191], 'McGarry': [1194, 1218, 1301, 5463, 5489], '268:': [1200, 5200, 5430, 5529], '5817-5822Abstract': [1201], '20Britton': [1208], 'Schultz': [1210], 'Esser': [1214, 5461, 5487], '92:': [1228], '1984-1988Crossref': [1229], '(127)': [1232], 'Scholar)': [1234, 2026, 2315, 4348, 4447, 6039], 'IB),': [1241], 'which': [1242, 5599, 5634], 'abundantly': [1245, 5800], 'heart,': [1247, 4925, 5246, 5812], 'skeletal': [1248], 'muscle,': [1249], 'brown': [1251, 5815], 'adipose': [1252, 5816], 'tissue': [1253], '(21Yamazaki': [1254], 'Shinohara': [1256, 1274, 3076, 3112], 'Shima': [1258, 1276, 3078, 3114], 'Terada': [1260, 1280, 3080, 3116], 'FEBS': [1262, 3082, 3118, 4339], 'Lett.': [1263, 3083, 3119, 4340], '363:': [1265], '41-45Crossref': [1266], '(112)': [1269, 5503], '22Yamazaki': [1272], 'Yamanaka': [1278, 3072, 3108], 'Biochim.': [1282, 3059], 'Biophys.': [1283, 3060], 'Acta.': [1284, 3061], '1307:': [1286], '157-161Crossref': [1287], '(102)': [1290], '23Esser': [1293], 'Brown': [1295, 3743, 3863], 'N.F.': [1296], 'Cowan': [1297], 'A.T.': [1298], '271:': [1307], '6972-6977Abstract': [1308], '(135)': [1316], 'inhibited': [1323], 'reversible': [1326], 'binding': [1327, 3524, 3642], 'malonyl-CoA,': [1329], 'first': [1331, 5663], 'committed': [1332], 'intermediate': [1333], 'synthesis': [1340], 'Malonyl-CoA': [1373], 'proposed': [1375], 'inhibit': [1377], 'hepatic': [1378, 5655, 5672, 5921], 'periods': [1383], 'synthesis.': [1387], 'Much': [1388], 'less': [1389, 3944], 'known': [1391, 1974, 3829, 4578, 5636], 'about': [1392], 'regulation': [1394, 4395, 6042], 'heart.': [1400, 4917, 5622, 5646], 'IC50of': [1402], 'malonyl-CoA': [1406, 1436, 1479], '100-fold': [1409], 'L-CPT': [1414], '(24McGarry': [1416], 'Mills': [1418], 'S.E.': [1419], 'Long': [1420], 'C.S.': [1421, 3748, 3868], 'Forter': [1422], '1983;': [1426, 1454], '214:': [1427], '21-28Crossref': [1428], '(467)': [1431], 'Scholar),': [1433, 1847, 2479, 3707, 5910], 'yet': [1434], 'concentration': [1437, 1716, 1736, 1754], 'similar': [1443], '(25Singh': [1444], 'Stakkestad': [1446], 'Bremer': [1448], 'Borrebaek': [1450], 'Anal.': [1452], '138:': [1455], '107-111Crossref': [1456], '(18)': [1458], 'observations': [1462], 'led': [1464], 'speculation': [1466], 'occurs,': [1473], 'least': [1475, 5219], 'part,': [1477, 5221], 'independent': [1480, 3102], 'mechanisms.': [1481, 5225], 'We': [1482, 5942, 5978], 'hypothesized': [1483], 'expression.': [1492, 3725], 'In': [1493, 1585, 2439, 4003, 4601, 5226, 5793, 5924], 'this': [1494, 3590, 3711, 5227, 5288, 5597, 5945], 'study': [1495], 'we': [1496, 3708, 5229, 5926], '(PPARα).': [1524], 'Our': [1525, 5829], 'suggest': [1527, 5626], 'mechanism': [1529, 5232, 5948], 'step,': [1542], 'levels.': [1547], 'Cardiac': [1548, 3343], 'were': [1550, 1601, 1633, 1729, 1763, 1863, 2091, 2185, 2204, 2268, 2368, 2398, 2431, 2499, 2511, 2518, 2546, 2668, 2742, 2794, 2816, 2843, 2960, 3263, 3346, 3394, 3535, 3807, 4044, 4063, 4187, 4257, 4313, 4569], 'prepared': [1551], '1-day-old': [1553, 2813], 'Sprague-Dawley': [1554], 'rats': [1555, 5370], 'described': [1557, 1780, 1925, 2247, 2288, 2549, 2592, 6040], 'brief,': [1586], 'ventricle': [1587, 1815, 2815], 'removed': [1589], 'digested': [1591], '0.2%': [1593], 'collagenase': [1594], '(Wako': [1595], 'Chemicals,': [1596], 'Richmond,': [1597], 'VA),': [1598], 'cells': [1600, 1629, 2367, 2510, 2587, 2855, 3806, 3984, 5452], 'pooled': [1602], "Dulbecco's": [1604, 1656], 'modified': [1605, 1657, 2402], "Eagle's": [1606, 1658], 'medium': [1607, 1651, 1659, 1768, 2388, 2504, 3219], '10%': [1609, 2391], 'horse': [1610], 'serum,': [1611], '5%': [1612, 2383, 2730], 'calf': [1614, 2393], '(Sigma)': [1616], 'subjected': [1618], 'differential': [1620], 'plating': [1621], '(1': [1622], 'h)': [1623], 'reduce': [1625], 'fibroblast': [1626], 'contamination.': [1627], 'Nonadherent': [1628], '(enhanced': [1630], 'cardiocyte': [1631], 'fraction)': [1632], 'plated': [1634, 2369], 'confluence': [1637], '60-mm': [1639], 'diameter': [1640], 'dishes': [1641, 2372], 'pretreated': [1642], 'collagen': [1644], '(Sigma).': [1645, 1679], 'After': [1646], '24': [1647, 2513], 'h': [1648, 2506, 2514, 2834], 'cell': [1650, 1766, 1811, 2396, 2503, 3917], 'switched': [1653], 'serum-free': [1655, 2836], '0.10': [1661], 'mm': [1662, 1685, 2820], '5-bromo-2′-deoxyuridine': [1663], '(Sigma),': [1664, 1668, 1672], '10': [1665, 1669, 2720, 4621], 'μg/ml': [1666, 1670], 'insulin': [1667], 'transferrin': [1671], '1': [1674, 2442, 2481], 'mg/ml': [1675], 'acid-free': [1677], 'BSA': [1678, 1707], 'diluted': [1682, 1731, 1749, 1764], '20': [1684], 'water': [1687, 1733, 1751], 'preheated': [1688], '70': [1690], '°C.': [1691], 'NaOH': [1692], '(1n)': [1693], 'added': [1695, 2432, 2500, 2708, 4258], 'dropwise': [1696], 'until': [1697], 'oleate': [1698, 1702, 1715, 2805, 2821, 2851, 2883, 2926, 2958, 3206, 3226, 3243, 3274, 3400, 3450, 3585, 3826, 3929, 3951, 3976, 4075, 4082, 4107], 'solubilized.': [1700], 'then': [1704], 'complexed': [1705, 2822], '(molar': [1708], 'ratio': [1709], '7:1)': [1710], 'yield': [1712], 'final': [1714], '4.7': [1718], 'mm.': [1719, 1739, 1757], 'sodium': [1721, 1741], 'salts': [1722], 'n-decanoic': [1724], 'n-caproic': [1727], 'each': [1730, 2275, 2324, 2434, 3507], '100': [1738, 2334, 2427, 4598], 'salt': [1742], 'etomoxir': [1744, 3953, 3982, 4077, 4084, 4109, 4584], '(Research': [1745], 'Biochemicals': [1746], 'International)': [1747], '4': [1756, 3956, 4001, 4026, 4079, 4114, 4144], 'Each': [1758], 'these': [1760, 2808, 3303, 3397, 4148, 4368, 5364], 'stock': [1761], 'solutions': [1762], 'concentrations': [1771, 3296], 'outlined': [1772], 'under': [1773], '"Results."': [1774], 'RNA': [1775, 1802, 1897], 'blotting': [1776], 'performed': [1778, 2286, 2399, 2547, 2669, 4064, 4188, 4203, 4268], '(26Kelly': [1781], 'Gordon': [1783, 5402], 'J.I.': [1784, 5403], 'Alpers': [1785, 5404], '264:': [1793, 5412], '18921-18925Abstract': [1794, 5413], 'Total': [1801], 'isolated': [1804, 1899, 2811], 'rat': [1806, 1826, 2281, 2814], 'neonatal': [1807, 2282], 'mouse': [1814, 1831, 1894, 2452, 2618, 4331, 5584], 'using': [1816, 1868, 1881, 2029, 2101, 2161, 2316, 2400, 3265, 4936], 'RNAzol': [1818], '(Tel-Test,': [1819], 'Inc.)': [1820], 'method.': [1821], 'Probes': [1822], 'included': [1824], 'cDNA,': [1829, 2492], 'ATPase': [1832, 2912], 'subunit': [1833, 2913], 'e': [1834], 'cDNA': [1835, 1849, 2454, 2620], '(27Levy': [1836], 'F.H.': [1837], '41:': [1844], 'C457-C465Crossref': [1845], 'probe': [1850, 2647, 2655, 2714, 4227], '18': [1852], 'S': [1853], 'ribosomal': [1854], 'RNA,': [1855], 'β-actin': [1859, 2890], 'cDNA.': [1860], 'Band': [1861], 'intensities': [1862], 'quantified': [1864], 'laser': [1866], 'densitometry': [1867], 'LKB': [1870], 'Ultrascan': [1871], 'XL': [1872], '(Matsushita': [1873], 'Electric': [1874], 'Industrial': [1875], 'Co.,': [1876], 'Ltd.)': [1877], 'phosphorimaging': [1880], 'Bio-Rad': [1883], 'GS': [1884], '525': [1885], 'Molecular': [1886], 'Imager': [1887], 'System.': [1888], 'For': [1889, 2323, 2356, 2807], 'Northern': [1890, 4536], 'blot': [1891, 4537], 'analyses': [1892], 'tissues,': [1895], 'total': [1896], 'ventricles': [1901], 'adult': [1903, 4558, 5620], '(2–3-month-old)': [1904], 'male': [1905], 'age-matched': [1911, 4451], 'production': [1915, 4906], 'characterization': [1918], 'lacking': [1921, 2489], '(28Lee': [1926, 4477, 5716, 5764], 'S.S.T.': [1927, 4420, 4478, 5717, 5765], 'Pineau': [1928, 4421, 4479, 5718, 5766], 'Drago': [1930, 4423, 4481, 5720, 5768], 'Lee': [1932, 4425, 4483, 5722, 5770], 'E.J.': [1933, 4426, 4484, 5723, 5771], 'Owens': [1934, 4427, 4485, 5724, 5772], 'J.W.': [1935, 4428, 4486, 5725, 5773], 'Kroetz': [1936, 4429, 4487, 5726, 5774], 'Fernandez-Salguero': [1938, 4431, 4489, 5728, 5776], 'Westphal': [1940, 4433, 4491, 5730, 5778], 'Gonzalez': [1942, 4435, 4493, 4518, 5732, 5780, 5982], 'F.J.': [1943, 4436, 4494, 4519, 5733, 5781], '3012-3022Crossref': [1949, 4442, 4500, 5739, 5787], '(1506)': [1952, 4445, 4503, 5742, 5790], '5′-flanking': [1956, 2065, 2145, 2991, 3018, 3132, 3372, 3466], 'cloned': [1965, 2994, 3147, 4045], 'PCR': [1967, 2046, 2094, 2138, 2164, 2183, 2615, 2996], 'amplification': [1968, 2095, 2139, 2997], 'BAC': [1971, 2098, 3000], 'subclone': [1972, 2099, 3001], 'template': [1973, 2053, 2100, 3002], 'contain': [1976], '(GenBank': [1981], 'data': [1982, 3304], 'accession': [1984], 'number': [1985], 'U62317;': [1986], 'gift': [1988, 2678, 2694], 'Institute': [1991], 'Genomic': [1993], 'Research,': [1994], 'Rockville,': [1995], 'MD).': [1996], '1025': [2000, 2070, 3135, 3376], '12': [2002, 2068, 2152, 3137], 'bp': [2003, 2071, 3385, 3592], '5′': [2004, 2111, 2120, 2155, 2163, 3093, 3140], 'initiation': [2007], 'codon': [2008, 2076, 2124, 2159, 3144, 3392], 'adenine': [2009, 2077, 2160, 3393], 'amplified': [2028], 'proofreading': [2031], 'Pwo': [2033], '(Boehringer': [2034], 'Mannheim).': [2035, 2322], 'Automated': [2036], 'DNA': [2037, 2147, 2410, 2992, 3019, 3373, 3478, 4160], 'sequencing': [2038], 'confirmed': [2039, 4283, 4308], 'nucleotide': [2042, 3501], 'product': [2047], '100%': [2049], 'identical': [2050, 4120], 'sequence.': [2054], 'MCPT.Luc.1025': [2055, 2109, 3160, 3169, 3195, 3239, 3279], 'constructed': [2057, 2205], 'cloning': [2059, 2616], 'start': [2075, 2123, 2158, 3042, 3104, 3143, 3391], 'promoterless': [2080, 3155, 3182], 'pGL2-Basic': [2081], '(Promega).': [2083], 'deletion': [2085, 3351], 'constructs': [2086, 2200, 3409], 'MCPT.Luc.915,': [2087], 'MCPT.Luc.781,': [2088], 'MCPT.Luc.724': [2090, 3414, 3423], 'generated': [2092, 2136, 2613], 'same': [2103], '3′': [2104], 'primer': [2105, 2165], 'primers': [2112], 'beginning': [2113], '915,': [2114], '781,': [2115], '724': [2117, 3383], 'adenine,': [2125], 'respectively.': [2126], 'point': [2131, 4008, 4118], 'mutant': [2132, 4009], 'construct,': [2133], 'MCPT.Luc.781m1,': [2134], 'genomic': [2146], 'extending': [2148, 3374], '781': [2150, 3380], 'cytidine': [2168, 3544], 'guanine': [2170, 3552], 'mismatch': [2171], 'substitution': [2172, 3545, 3593], 'position': [2174, 3551], '−771': [2175], '(as': [2176], 'illustrated': [2177], 'Fig.': [2179, 2859, 3198, 3232, 3563, 4000, 4113], '3': [2180, 3416, 3516, 3564, 3595], 'B).': [2181, 3300, 3565, 3596, 4080, 4115, 4145, 4628], 'All': [2182, 2760], 'products': [2184], 'ligated': [2186], 'XhoI': [2189], '(5′)': [2190], 'HindIII': [2192], '(3′)': [2193], 'sites': [2194, 3105, 3643], 'pGL2-Basic.': [2196], 'promoter-reporter': [2199, 2276], 'MCPT(FARE)2TKLuc': [2201, 4066, 4097], 'MCPT(FAREm1)2TKLuc': [2203], 'ligation': [2207], 'copies': [2210, 4041, 4130], 'double-stranded': [2213, 4280], 'oligonucleotide': [2214, 2654, 4208, 4282], '(single-copy': [2215], 'sense-strand': [2216], 'sequences:': [2217], 'MCPT(FARE)2TKLuc:': [2218], '5′-GATCCGGTGACCTTTTCCCTACAG-3′': [2219], 'MCPT(FAREm1)2TKLuc:': [2221], '5′-GATCCGGTGACgTTTTCCCTACAG-3′': [2222], '(lowercase': [2223], 'bold': [2224], 'letter': [2225], 'denotes': [2226], 'mutation))': [2227], 'BamHI': [2229], 'overhangs': [2230], 'aBamHI': [2232], 'site': [2233], 'herpes': [2237, 4049], 'simplex': [2238, 4050], 'virus': [2239, 2349, 4051], '(TK)': [2242], 'previously': [2248], '(16Carter': [2249, 2550, 2593], 'PCR-generated': [2266], 'mutations': [2267], 'excluded': [2269], 'automated': [2271], 'analysis': [2273, 3480], 'plasmid.': [2277], 'Transient': [2278, 2395], 'transfection': [2279, 2354, 3215], 'N-[1-(2,': [2317], '3-dioleoyloxy)propyl]-N,N,N-trimethylammonium': [2318], 'methylsulfate': [2319], '(DOTAP;': [2320], 'Boehringer': [2321], 'transfection,': [2325], '1–2': [2326], 'μg': [2327, 2443, 2482], 'cotransfected': [2332, 3808, 3985], 'ng': [2335, 2428], 'pRSVβ-Gal,': [2337], 'β-galactosidase': [2342, 2526], 'downstream': [2344], 'Rous': [2347], 'sarcoma': [2348], 'promoter,': [2350, 4039], 'efficiency.': [2355], 'cotransfection': [2358, 3995, 4017], 'vector,': [2364], 'HepG2': [2366, 3916], '12-well': [2371], '2': [2374, 3162, 3199, 3233, 3299, 4244], '×': [2375], '105cells/well': [2376], 'maintained': [2378], 'atmosphere': [2381], 'CO2': [2384], 'minimal': [2386, 3932], 'essential': [2387], 'supplemented': [2389], 'serum.': [2394], 'transfections': [2397, 3345, 3534], 'calcium-phosphate': [2403], 'precipitation': [2404], 'method': [2405], '(29Gorman': [2406], 'C.': [2407, 5486, 6013], 'Glover': [2408], 'D.M.': [2409], 'Cloning:': [2411], 'Practical': [2413], 'Approach.': [2414], 'II.': [2415], 'IRL': [2416], 'Press,': [2417], 'Oxford1985:': [2418], '143-190Google': [2419], 'Four': [2421], 'micrograms': [2422], 'pRSVβ-Gal': [2430], 'well': [2435, 5659, 5919], 'cells.': [2438, 2904], 'some': [2440], 'wells,': [2441], 'pCDM.PPAR,': [2445], 'mammalian': [2447, 3812, 4654, 4862, 4916, 5621], 'vector': [2449, 2487, 2571, 2624, 3183, 3442, 3814], '(30Gulick': [2455, 3832, 5886], 'Caira': [2459, 3836, 5890], '11012-11016Crossref': [2474, 3851, 5905], '(491)': [2477, 3854, 5908], 'pCDM(−),': [2484], 'backbone': [2488, 3184, 3443], 'added.': [2494], 'Oleate,': [2495], 'etomoxir,': [2496, 3828, 4576], 'vehicle': [2498, 2829, 2900], '16': [2505], 'after': [2507], 'transfection.': [2508], 'harvested': [2512], 'later.': [2515], 'Luciferase': [2516, 3366], 'activities': [2517], 'determined': [2519, 2743], 'standard': [2522, 2641, 2768], 'luciferin-ATP': [2523], 'assay,': [2524], 'measured': [2529], 'Galacto-Light': [2532], 'chemiluminescence': [2533], 'assay': [2534], '(Tropix,': [2535], 'Bedford,': [2536], 'MA)': [2537], 'Analytical': [2540], 'Luminescence': [2541], 'Monolight': [2542], '2010': [2543], 'luminometer.': [2544], 'EMSAs': [2545, 4186], 'pT7lac-RXRα': [2568], 'bacterial': [2569, 2586], 'generously': [2573], 'provided': [2574], 'Dr.': [2576, 2680, 2696, 5980, 5993], 'Tod': [2577, 5994], '(Harvard': [2579, 5996], 'University).': [2580], 'Nuclear': [2581], 'overproduced': [2584], 'partially': [2589], 'purified': [2590], 'pCal-n': [2610], '(m.PPAR)': [2611], 'pCAL-n': [2623], '(Stratagene)': [2625], 'vitro': [2630, 4220], 'transcription/translation': [2631], 'TnT': [2634], 'coupled': [2635, 4221], 'reticulocyte': [2636, 4222], 'lysate': [2637, 4223], 'system': [2638], '(Promega)': [2639], 'per': [2640, 4884], 'protocol.': [2642], 'sense': [2648], 'strand': [2649], '5′-GATCCGGTGACCTTTTCCCTACAG-3′.': [2652], 'Double-stranded': [2653], '32P-labeled': [2657], 'Klenow': [2659], '"fill-in"': [2660], '5′-GATC': [2663], 'overhang.': [2664], 'Antibody': [2665, 4305], '"supershift"': [2666], 'polyclonal': [2671, 4327], 'antibodies': [2672], 'directed': [2673, 2690], 'against': [2674, 2691], '(a': [2677, 2693], 'Michael': [2681], 'Arand,': [2682], 'University': [2683], 'Mainz),': [2685], 'monoclonal': [2688], 'antibody': [2689, 2703, 4328], 'RXRα': [2692, 4210, 4239, 4256, 4295, 4312, 4381], 'Pierre': [2697], 'Chambon,': [2698], 'INSERM,': [2699], 'Strasbourg,': [2700], 'France).': [2701], 'Specific': [2702], 'preimmune': [2705, 4356], 'sera': [2706, 4357], 'mixture': [2711], 'labeled': [2713], 'protein,': [2716, 2919], 'incubated': [2718], 'min': [2721], 'room': [2723], 'temperature,': [2724], 'followed': [2725, 2734], 'resolution': [2727], 'nondenaturing': [2731], 'polyacrylamide': [2732], 'gel': [2733], 'autoradiography.': [2736], 'Differences': [2737], 'mean': [2739, 2765, 2772], 'unpaired': [2745], "Student's": [2746], 't': [2747], 'test': [2748, 4029], 'analysis.': [2749], 'statistically': [2751], 'significant': [2752], 'difference': [2753], 'defined': [2755], 'P': [2757], '<': [2758, 2857], '0.05.': [2759], 'values': [2761], 'shown': [2762, 3230, 3636, 3730, 4457, 5086, 5539], 'represent': [2763], '±': [2766, 4552, 4596, 4599, 4620, 4624], 'error': [2769], '(S.E.).': [2773], 'determine': [2775, 2942, 3246, 3796, 4388], 'whether': [2776, 2943, 3247, 3797, 4030], 'delineated': [2795, 3209], 'ventricular': [2798], '(C18:1).': [2806], 'experiments,': [2809], 'exposed': [2817, 2849], '0.5': [2819], '(BSA)': [2827], '(BSA': [2830], 'alone)': [2831], '90': [2833], 'medium.': [2837], 'Mean': [2838], '4.5-fold': [2844], 'higher': [2845, 3175, 3992], 'compared': [2852, 2901, 4449, 4561], 'vehicle-treated': [2854], '(p': [2856], '0.01;': [2858], '1).': [2860], 'Expression': [2861], 'several': [2866, 5290, 5632], 'cycle': [2869, 4465, 5097, 5269, 5322, 5876], 'including': [2871], 'very-long-chain': [2872], 'also': [2877], 'increased': [2878, 3943, 4893], 'presence': [2881, 3491, 3822, 3949, 4022, 4071, 5604], '(data': [2884, 3185, 3580], 'shown).': [2886, 3187, 3582], 'level': [2888, 5104], 'mRNA,': [2891], 'loading,': [2895], 'different': [2898, 3575], 'oleate-treated': [2903], 'Similarly,': [2905], 'e,': [2914], 'affected': [2922, 3289], 'indicating': [2927, 3444], 'effect': [2931], 'does': [2932], 'involve': [2934], 'all': [2935], 'proteins.': [2940], 'oleate-induced': [2945], 'increase': [2946], 'occurs': [2952], 'repeated': [2961, 3264, 3347, 3536, 4570], 'transiently': [2965], 'gene.': [2983], '1013-bp': [2985], 'fragment': [2986], '(see': [3009], '"Materials': [3010], 'Methods").': [3012], 'contains': [3020, 3472, 5881], 'untranslated': [3022], 'exons,': [3023], '1A': [3024, 3097], '1B,': [3026], 'extend': [3028, 5259], '746': [3030], '633': [3032], '523': [3034], '470': [3036], 'codon,': [3043], 'respectively': [3044], '(31van': [3045], 'der': [3046, 3052], 'Leij': [3047], 'F.R.': [3048], 'Takens': [3049], 'van': [3051], 'Veen': [3053], 'A.Y.': [3054], 'Terpstra': [3055], 'Kuipers': [3057], 'J.R.G.': [3058], '1352:': [3063], '123-128Crossref': [3064], '(29)': [3067], '32Yamazaki': [3070], 'Hashimoto': [3074, 3110, 4516], '409:': [3085, 3121], '401-406Crossref': [3086, 3122], '(56)': [3089, 3125], 'ends': [3094], 'exons': [3096], '1B': [3099], 'function': [3100, 5834], '(32Yamazaki': [3106], '(from': [3134], 'adenine)': [3145], 'generate': [3159], '(Fig.': [3161, 3298, 3415, 3515, 3594, 3955, 4025, 4078, 4143, 4241, 4262, 4301, 4363, 4564, 4626], 'A).': [3163, 3200, 3417, 3957, 4002, 4027, 4566], 'basal': [3165, 3419, 3567, 5594], 'significantly': [3174, 3434, 3574, 4548], '(over': [3176], '15-fold)': [3177], 'markedly': [3189], '(approximately': [3196], '25-fold;': [3197], 'dose': [3202], 'dependence': [3203], 'repeating': [3211], 'myocyte': [3214, 3344], 'serum-deprived': [3218], '50,': [3221], '250,': [3222], '500': [3224], 'μm': [3225], 'versusvehicle': [3227], 'alone.': [3228], 'As': [3229, 4582], 'B,': [3234], 'increasing': [3242], 'concentration.': [3244], 'acid-induced': [3250], 'length-specific,': [3260], 'dose-response': [3261], 'decanoate': [3266, 3285], '(C10:0)': [3267], 'hexanoate': [3269, 3291], '(C6:0).': [3270], 'Compared': [3271, 4873], 'response,': [3275], 'only': [3282], 'modestly': [3283], 'any': [3293], 'tested': [3297], 'Taken': [3301, 4146, 4366, 5859], 'together,': [3302, 4147, 4367], 'indicate': [3305, 3599, 5913], 'activated': [3312, 3733, 3800, 4086, 5548, 5950], 'consistent': [3328, 5601], 'acids.': [3342], 'MCPT.Luc': [3350], 'series': [3352], 'localize': [3354], 'oleate-responsive': [3356, 3487], 'within': [3358, 3553], 'region.': [3365], 'plasmids': [3368], '(MCPT.Luc.1025),': [3377], '915': [3378], '(MCPT.Luc.915),': [3379], '(MCPT.Luc.781),': [3381], '(MCPT.Luc.724)': [3384], 'experiments.': [3398], 'preserved': [3403], 'MCPT.Luc.915': [3406], 'MCPT.Luc.781': [3408, 3431, 3540, 3579, 3817, 3928, 3942, 3969, 3989], 'but': [3410, 3432], 'absent': [3412, 5760], 'still': [3433], 'greater': [3435, 4902], 'promoterless,': [3440], 'lack': [3447], 'due': [3454], 'loss': [3457], 'function.': [3460], 'Thus,': [3461, 4896, 5208], '−781': [3469], '−724': [3471], 'element.': [3477, 4156, 5558], 'revealed': [3489], 'imperfect': [3494], 'separated': [3497], 'single': [3500, 3591], '(DR-1;−775-TGACCTTTTCCCT-−763).': [3502], 'antisense': [3504], 'half-site': [3508, 3557], 'putative': [3511], 'acid-responsive': [3513], 'B)': [3517], 'conforms': [3518], 'consensus': [3521, 3549], '((A/G)GG(T/G)NA)': [3522], 'class': [3525], 'superfamily.': [3532], 'mutated': [3539], 'invariant': [3548], 'second': [3550], '5′-most': [3555], 'DR-1': [3560, 3602, 3638], '(MCPT.Luc.781m1;': [3562], 'MCPT.Luc.781m1': [3571, 3819, 4011, 4125], 'However,': [3583], 'abolished': [3588, 4142], '−775': [3605], '−763': [3607], 'required': [3609], 'myocytes.': [3620], 'This': [3621], 'will': [3623], 'be': [3624, 3732, 5568], 'referred': [3625], 'thefatty': [3628], 'responseelement-1': [3630], 'FARE-1.': [3632, 4200], 'Previous': [3633, 4454, 5083], 'elements': [3639, 4161], 'serve': [3640], 'PPAR·RXR': [3645], 'heterodimers': [3646, 4195], '(33Lemberger': [3647, 3689], 'Desvergne': [3649, 3691], 'Wahli': [3651, 3693, 3751, 3871], 'W.': [3652, 3694, 3752, 3872], 'Annu.': [3653, 3695], 'Cell': [3655, 3697], 'Dev.': [3656, 3698], '12:': [3659, 3701], '335-363Crossref': [3660, 3702], '(640)': [3663, 3705], 'Given': [3666], 'previous': [3670, 5863], 'demonstrating': [3672], 'regulates': [3675, 5916], 'other': [3681, 4375, 5305], 'peroxisomal': [3684, 4461, 5750], 'speculated': [3709], 'candidate': [3715], 'acid-mediated': [3719], 'Indeed,': [3726], 'has': [3728, 5825], '(34Kliewer': [3737], 'Sundseth': [3739, 3859], 'S.S.': [3740, 3860], 'Jones': [3741, 3861], 'P.J.': [3744, 3864], 'Wisely': [3745, 3865], 'G.B.': [3746, 3866], 'Koble': [3747, 3867], 'Devchand': [3749, 3869], 'Willson': [3753, 3873], 'T.M.': [3754, 3874], 'Lenhard': [3755, 3875], 'J.M.': [3756, 3758, 3876, 3878, 4509], 'Lehmann': [3757, 3877], '4318-4323Crossref': [3768, 3888], '(1898)': [3771, 3891], '35Forman': [3774, 3894], 'Chen': [3776, 3896], 'Evans': [3778, 3898, 4175], 'R.M.': [3779, 3899, 4176], '4312-4317Crossref': [3789, 3909], '(1870)': [3792, 3912], 'PPARα,': [3802, 5639], 'hepatoma': [3803], 'G2': [3804], '(HepG2)': [3805], '(pCDM.PPAR)': [3815], 'absence': [3824, 3963, 4020, 4073], 'activators': [3831, 4024], '34Kliewer': [3857], 'line': [3918], 'chosen': [3920], 'because,': [3921], 'contrast': [3923], 'allowing': [3933], '"null"': [3936], 'background.': [3937], '1.5-fold': [3946], 'alone': [3954, 3996, 4085, 4234, 4240], 'pCDM.PPAR': [3960, 3987, 3994, 4016, 4068], 'exogenous': [3966], 'nearly': [3971], '7-fold.': [3972], 'addition': [3974, 4105, 4354, 5794], 'inhibitor': [3981], '2–3.5-fold': [3991], '(total': [3997, 4110], '16–24-fold;': [3999], 'contrast,': [4004, 4602], 'could': [4032], 'confer': [4033], 'responsiveness': [4035, 4140], 'TK': [4052], '(MCPT(FARE)2TKLuc).': [4060], 'Neither': [4081], 'nor': [4083], 'MCPT(FARE)2TKLuc.': [4087], 'Overexpression': [4088], 'resulted': [4091], '5-fold': [4094], 'additional': [4101], '1.6–2-fold': [4102], 'induction': [4103, 5235, 5748], '8–10-fold;': [4112], 'When': [4116], 'mutation': [4119], 'present': [4123, 4314], 'introduced': [4127], 'both': [4129, 4253], 'context': [4135], 'TKLuc': [4137], '(MCPT(FAREm1)2TKLuc),': [4138], 'binds': [4158], 'cognate': [4159], 'heterodimer': [4164], 'RXR': [4166], '(36Kliewer': [4167], 'Umesono': [4169], 'K.': [4170, 4515, 5195, 5425, 5524], 'Noonan': [4171], 'D.J.': [4172], 'Heyman': [4173], 'Nature.': [4177, 5681], '1992;': [4178, 4341], '358:': [4179], '771-774Crossref': [4180], '(1525)': [4183], 'characterize': [4190], 'interaction': [4192, 4300], 'PPARα·RXRα': [4194], 'PPARα-responsive': [4198], 'element,': [4199], 'EMSA': [4201], 'radiolabeled': [4206], 'probe,': [4209], '(produced': [4211], 'overexpression': [4213], 'bacteria),': [4215], 'byin': [4219], 'transcription/translation.': [4224], 'formed': [4228, 4251, 4291], 'light': [4230], 'complex': [4231, 4237, 4250, 4287, 4321], 'no': [4236], '5,': [4242, 4263, 4302], 'lanes': [4243, 4303], '3).': [4246], 'prominent': [4248, 4286], 'FARE·protein': [4249], 'when': [4252], 'incubation': [4261], 'lane': [4264], '4).': [4265], 'Competition': [4266], 'molar': [4271], 'excess': [4272], 'unrelated,': [4278], 'size-matched,': [4279], 'nonspecific': [4281], 'lowest': [4289], 'represented': [4296], 'DNA-protein': [4299], '5–7).': [4304], 'recognition': [4306], 'FARE-1/protein': [4317, 4320], 'complex.': [4318], 'supershifted': [4323], 'either': [4325], 'recognizes': [4330], '(37Gebel': [4333], 'Arand': [4335], 'Oesch': [4337], 'F.': [4338, 5456, 5484, 6021], '309:': [4342], '37-40Crossref': [4343], '(103)': [4346], 'anti-RXRα': [4351], 'antibody,': [4352], 'whereas': [4353], 'alter': [4360], 'its': [4361], '5,lanes': [4364], '8–10).': [4365], 'findings': [4369], 'that,': [4371, 5587], 'reported': [4373], 'elements,': [4378], 'bind': [4382], 'heterodimer.': [4386], 'importance': [4390], 'vivo,': [4405, 5589], '(PPARα−/−;': [4417], 'Ref.': [4418], '28Lee': [4419], 'controls': [4452, 4563], '(PPARα+/+).': [4453], 'reduced': [4470, 5576, 5707], 'PPARα−/−': [4475, 4559, 4617, 5762, 5991], '38Aoyama': [4506], 'Peters': [4508], 'Iritani': [4510], 'Nakajima': [4512], 'Furihata': [4514], '1998;': [4523, 6027], '273:': [4524, 6028], '5678-5684Abstract': [4525], '(754)': [4533], '(by': [4550], '51': [4551], '9%)': [4553], '6': [4565, 4627], '5-day': [4573], 'administration': [4574], 'PPARα.': [4581, 5256, 5941, 6049], 'expected,': [4583], 'PPARα+/+': [4593], '(194': [4595], '15versus': [4597], '7).': [4600], 'PPAR': [4604], '(64': [4619], 'versus': [4622], '58': [4623], '10)': [4625], 'confirm': [4631], 'vivo.': [4647], 'preference': [4651], 'controlled': [4658], 'diverse': [4665], 'conditions': [4669], '4Bishop': [4690], 'produces': [4833], 'through': [4836, 5940], 'catabolism': [4837], 'lactate': [4841], 'switches': [4864], 'substrate.': [4872], 'glucose,': [4875], 'provides': [4881, 4900], 'more': [4882], 'mole': [4885], 'substrate,': [4887], 'albeit': [4888], 'expense': [4891], 'oxygen': [4894], 'consumption.': [4895], 'capacity': [4903, 5210, 5805], 'meet': [4908], 'demands': [4911], 'imposed': [4912], 'postnatal': [4915], 'myocardium': [4927], 'reverts': [4928], 'pattern': [4935], '39Nagao': [5190, 5420], 'Parimoo': [5192, 5422, 5521], 'Tanaka': [5194, 5424, 5523], '24114-24124Abstract': [5201, 5431, 5530], 'dictated,': [5217], 'report': [5228], 'describe': [5230], 'namely': [5247], 'acid-activated': [5253], 'receptor,': [5255], 'paradigm': [5263], 'established': [5264], 'import,': [5275], 'highly': [5277], 'pathway.': [5285, 5313], 'Prior': [5286], 'report,': [5289], 'lines': [5291], 'evidence': [5293], 'suggested': [5294], 'First,': [5314], 'up-regulated': [5325], 'ingestion': [5330], 'acid-enriched': [5334], 'diet': [5335], 'suckling': [5338], 'period': [5339], 'falls': [5366], 'upon': [5367], 'weaning': [5368], '26Kelly': [5400], 'Second,': [5438], 'hepatocytes': [5448], 'pancreatic': [5450], 'islet': [5451], '(40Assimacopoulos-Jeannet': [5455], 'Thumelin': [5457], 'Roche': [5459], 'E.': [5460, 6015], 'Prentki': [5465], '272:': [5471], '1659-1664Abstract': [5472], '(137)': [5480], '41Chatelain': [5483], 'Kohl': [5485], 'Girard': [5491], 'Pegorier': [5493], 'J-P.': [5494], 'Eur.': [5495], '235:': [5499], '789-798Crossref': [5500], 'Third,': [5506], 'fasting': [5514], '(39Nagao': [5519], 'here': [5540], 'FARE-1,': [5554], 'can': [5567], 'conferred': [5569], 'promoter.': [5573], 'PPAR−/−': [5583], 'suggests': [5586], 'influence': [5592], 'circulating': [5606], 'lipids': [5607], 'reliance': [5609], 'strongly': [5625], 'intracellular': [5628], 'derivatives,': [5631], 'activate': [5638], 'comprise': [5640], 'signaling': [5643], 'metabolism': [5657], 'established.': [5660], 'identified': [5664], 'proliferators': [5676, 5758], '(42Issemann': [5677], 'I.': [5678], 'Green': [5679], '1990;': [5682], '347:': [5683], '645-650Crossref': [5684], '(3059)': [5687], 'target': [5694, 5752], 'peroxisomal,': [5700], 'cytochrome': [5701], 'P450,': [5702], 'Further,': [5745], 'expected': [5747], 'liver,': [5796], 'tissues': [5802, 5824], 'high': [5804], 'such': [5810, 5972], 'kidney,': [5813], 'tissue.': [5817], 'extrahepatic': [5823], 'characterized.': [5828], 'one': [5832], 'heart:': [5838], 'I,': [5846], 'mitochondria.': [5858], 'together': [5860], 'observation': [5864], 'cardiac-enriched': [5873], 'our': [5911], 'summary,': [5925], 'speculate': [5943], 'component': [5953], 'coordinate': [5956], 'pathways': [5963], 'birth': [5965], 'altered': [5968], 'settings': [5971], 'failure.': [5977], 'thank': [5979], 'Frank': [5981], '(National': [5983], 'Cancer': [5984], 'Institute)': [5985], 'use': [5988], 'mice,': [5992], 'University)': [5997], 'helpful': [5999], 'discussions,': [6000], 'Hall': [6003], 'expert': [6005], 'secretarial': [6006], 'assistance.': [6007], 'Recently,': [6008], 'Mascaró': [6009], 'et': [6010], 'al.': [6011], '(43Mascaró': [6012], 'Acosta': [6014], 'Ortiz': [6016], 'Marrero': [6018], 'Hegardt': [6020], 'Haro': [6022], '8560-8563Abstract': [6029], '(283)': [6037]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1965397552', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 9}, {'year': 2021, 'cited_by_count': 12}, {'year': 2020, 'cited_by_count': 12}, {'year': 2019, 'cited_by_count': 8}, {'year': 2018, 'cited_by_count': 13}, {'year': 2017, 'cited_by_count': 7}, {'year': 2016, 'cited_by_count': 14}, {'year': 2015, 'cited_by_count': 13}, {'year': 2014, 'cited_by_count': 9}, {'year': 2013, 'cited_by_count': 24}, {'year': 2012, 'cited_by_count': 16}], 'updated_date': '2024-12-17T12:30:12.679309', 'created_date': '2016-06-24'}