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'UKSearch': [75, 96, 117, 140, 163, 186, 232, 253, 274, 297, 320, 343], 'more': [77, 98, 119, 142, 165, 188, 234, 255, 276, 299, 322, 345], 'papers': [78, 99, 120, 143, 166, 189, 235, 256, 277, 300, 323, 346], 'by': [79, 100, 121, 144, 167, 190, 236, 257, 278, 301, 324, 347, 449, 585, 588, 828, 973, 1000], 'this': [80, 101, 122, 145, 168, 191, 237, 258, 279, 302, 325, 348, 411, 479], 'authorBianca': [81, 238], 'Beghé,': [82, 239], 'Bianca': [83, 240], 'Beghé': [84, 241], 'authorSteve': [102, 259], 'Turner,': [103, 260], 'Steve': [104, 261], 'Turner': [105, 262], 'authorLesley': [123, 280], 'J.': [124, 127, 281, 284, 732], 'Hinks,': [125, 282], 'Lesley': [126, 283], 'Hinks': [128, 285], 'authorIan': [146, 303], 'N.M.': [147, 150, 304, 307], 'Day,': [148, 305], 'Ian': [149, 306], 'Day': [151, 308, 629, 656, 681], 'authorW.': [169, 326], 'Martin': [170, 173, 327, 330], 'Howell,': [171, 328], 'Howell': [174, 331, 847], 'author': [192, 349], 'First': [350], 'published:': [351], '28': [352], 'September': [353], '1999': [354, 535], 'https://doi.org/10.1002/(SICI)1098-1004(199910)14:4<340::AID-HUMU10>3.0.CO;2-ZCitations:': [355], '27AboutPDF': [356], 'ToolsRequest': [357], 'permissionExport': [358], 'citationAdd': [359], 'to': [360, 382, 405, 1035, 1059, 1065, 1360], 'favoritesTrack': [361], 'citation': [362], 'ShareShare': [363], 'Give': [364], 'accessShare': [365, 368], 'full': [366], 'text': [367], 'full-text': [369, 384, 408], 'accessPlease': [370], 'review': [371], 'our': [372, 500], 'Terms': [373, 396], 'Conditions': [375, 398], 'Use': [377], 'check': [379], 'box': [380], 'below': [381, 404], 'share': [383, 406], 'version': [385, 409], 'article.I': [387], 'have': [388], 'read': [389], 'accept': [391], 'the': [392, 402, 423, 426, 436, 452, 483, 525, 556, 573, 589, 615, 695, 739, 798, 830, 901, 912, 1074, 1119, 1184, 1290, 1323], 'Wiley': [393], 'Online': [394], 'Library': [395], 'UseShareable': [400], 'LinkUse': [401], 'link': [403], 'a': [407, 756, 946, 975, 1066], 'article': [412], 'with': [413, 596, 1003], 'your': [414], 'friends': [415], 'colleagues.': [417], 'Learn': [418], 'more.Copy': [419], 'URL': [420], 'Abstract': [421], 'In': [422, 478], 'near': [424], 'future': [425, 1260], 'number': [427], 'SNPs': [429, 468], 'identified': [430], 'mapped': [432], 'will': [433, 443], 'increase': [434], 'need': [437], 'high': [439], 'throughput': [440, 464], 'SNP': [441], 'be': [444], 'paramount': [445], 'comprehensive': [447, 735], 'examination': [448], 'association': [450], 'role': [453], 'genomic': [455], 'regions': [456], 'in': [457, 471, 474, 497, 499, 511, 869, 952, 971, 1117, 1182, 1241, 1289, 1295, 1322], 'disease': [458, 871, 1381], 'traits.': [459, 1382], 'A': [460, 734, 1317], 'range': [461], 'higher': [463], 'is': [469], 'now': [470], 'routine': [472], 'use': [473, 498, 944, 1346], 'many': [475], 'laboratories': [476], 'worldwide.': [477], 'report,': [480], 'we': [481], 'analyse': [482], 'relative': [484], 'advantages': [485], 'disadvantages': [487], 'such': [490], 'methods,': [491], 'TaqMan,': [492], 'PCR-SSOP,': [493], 'ARMS-MADGE,': [495], 'currently': [496], 'laboratories.': [501, 529], 'Throughputs': [502], 'achievable': [503], 'are': [504, 508], 'similar,': [505], 'but': [506], 'there': [507], 'major': [509], 'differences': [510], 'cost': [512], 'time': [514], 'set-up,': [516], 'equipment,': [517], 'consumables,': [518], 'staff': [520], 'time,': [521], 'which': [522], 'may': [523], 'determine': [524], 'choice': [526], 'individual': [528], 'Hum': [530, 884], 'Mutat': [531], '14:340–347,': [532], '1999.': [533, 687], '©': [534], 'Wiley-Liss,': [536], 'Inc.': [537], 'REFERENCES': [538], 'Baron': [539], 'H,': [540, 1199, 1279], 'Fung': [541], 'S,': [542, 708, 720, 1104], 'Aydin': [543], 'A,': [544, 716, 890, 1139, 1165], 'Bähring,': [545], 'Luft': [546], 'FC,': [547], 'Schuster': [548], 'H.': [549, 1110, 1315], '1996.': [550, 733, 1258], 'Oligonucleotide': [551], 'ligation': [552], 'assay': [553, 1321], '(OLA)': [554], 'diagnosis': [557], 'familial': [559], 'hypercholesterolemia.': [560], 'Nat': [561, 955, 1080], 'Biotechnol': [562], '14:': [563], '1279–': [564], '1282.Medline': [565], 'Bignon': [566, 768], 'JD,': [567], 'Fernandez-Vina': [568, 766], 'MA.': [569], '1997.': [570, 770, 942], 'Protocols': [571], '12th': [574], 'International': [575, 617, 800, 895, 914], 'Histocompatibility': [576, 618, 754, 801, 896, 915], 'Workshop': [577, 619, 802, 897, 916], 'HLA': [581, 781, 1088], 'class': [582, 782, 1089], 'II': [583, 783, 1090], 'alleles': [584], 'amplification': [587, 1114, 1185], 'polymerase': [590, 824, 1120, 1148], 'chain': [591, 825, 1121, 1149], 'reaction': [592, 826], '(PCR)': [593], 'hybridization': [595, 1351], 'sequence': [597, 1359], 'specific': [598, 823], 'probes': [600, 774], '(SSOP).': [601], 'In:': [602, 785, 905], 'D': [603, 786], 'Charron,': [604, 787], 'editor.': [605, 788], 'Genetic': [606, 789], 'diversity': [607, 790], 'HLA—functional': [609, 792], 'medical': [611, 794], 'implications:': [612, 795], 'proceedings': [613, 796], 'Twelfth': [616, 799], 'Conference,': [621, 804, 918], 'vol.': [622, 805], '1.': [623, 806, 920], 'Paris:': [624, 807], 'EDK.': [625, 808], 'p': [626, 809, 925], '584–': [627], '595.': [628, 697], 'INM,': [630, 657, 682], 'Humphries': [631], 'SE.': [632], '1994.': [633, 1208], 'Electrophoresis': [634], 'genotyping:': [636], 'microtitre': [637], 'on': [643, 743], 'horizontal': [644], 'polyacrylamide': [645], '(H-PAGE)': [646], 'gels,': [647], 'Hydrolink': [648], 'or': [649], 'agarose.': [650], 'Anal': [651], 'Biochem': [652], '222:': [653], '389–': [654], '395.Medline': [655], 'Spanakis': [658], 'E,': [659, 724, 1019, 1222], 'Palamand': [660], 'D,': [661, 712, 1015], 'Weavind': [662], 'GP,': [663], "O'Dell": [664, 683], 'SD.': [665], '1998.': [666, 930, 1087, 1093], 'Microplate-array': [667], 'diagonal-gel': [668], 'melt-MADGE:': [672], 'tools': [673], 'molecular-genetic': [675], 'epidemiology.': [676], 'TIBTECH': [677], '16:': [678], '287–': [679], '290.Medline': [680], 'SD,': [684], 'X-H': [685], 'Chen.': [686], 'Microplate': [688], 'Fluorimager®': [696], 'Application': [698], 'Note,': [699], 'Amersham': [700], 'Pharmacia': [701], 'Biotech': [702], '(in': [703], 'press).': [704], 'Dib': [705], 'C,': [706, 710, 1046, 1050, 1135, 1171], 'Fauré': [707], 'Fizames': [709], 'Samson': [711], 'Drouot': [713], 'N,': [714, 1023, 1025, 1173, 1255], 'Vignal': [715], 'Millasseau': [717], 'P,': [718, 1052], 'Marc': [719], 'Hazan': [721], 'J,': [722, 730], 'Seboun': [723], 'Lathrop': [725, 1053, 1372], 'M,': [726, 1017, 1054, 1137, 1197, 1201, 1203, 1226, 1283], 'Gyyapay': [727], 'G,': [728, 1108], 'Morissette': [729], 'Weissenbach': [731], 'genetic': [736, 947, 969, 1037, 1262], 'map': [737, 948, 977], 'human': [740, 1266], 'genome': [741], 'based': [742], '5,264': [744], 'microsatellites.': [745], 'Nature': [746], '380:': [747], '152–': [748], '154.Medline': [749], 'P': [750], 'Dyer,': [751], 'editors.': [752, 908], '1993.': [753, 997, 1057, 1235], 'testing:': [755], 'practical': [757], 'approach.': [758], 'Oxford:': [759, 921], 'IRL': [760], 'Press': [761], 'at': [762], 'Oxford': [763, 922], 'Press.': [765, 924], 'MA,': [767, 856], 'JD.': [769], 'Primers': [771], '(SSOP)': [775], 'used': [776], 'alleles.': [784], '596–': [810], '632.': [811], 'Holland': [812], 'PM,': [813], 'Abramson': [814], 'RD,': [815], 'Watson': [816], 'R,': [817, 1027, 1106, 1224], 'Gelfand': [818], 'DH.': [819, 862], '1991.': [820, 893, 1142], 'Detection': [821], 'product': [827], 'utilizing': [829], '5¢-3¢': [831], 'exonuclease': [832], 'activity': [833], 'Thermus': [835], 'aquaticus': [836], 'polymerase.': [838], 'Proc': [839, 983], 'Natl': [840, 984], 'Acad': [841, 985], 'Sci': [842, 986], 'USA': [843, 987], '88(16):': [844], '7276–': [845], '7280.Medline': [846], 'WM,': [848], 'Leung': [849], 'ST,': [850], 'Jones': [851], 'DB,': [852], 'Nakshabendi': [853], 'I,': [854], 'Hall': [855], 'Lanchbury': [857], 'JS,': [858], 'Ciclitira': [859], 'PJ,': [860], 'Wright': [861], '1995.': [863, 1030, 1286, 1374], 'HLA-DRB,': [864], '-DQA': [865], '-DQB': [867], 'coeliac': [870], 'enteropathy-associated': [873], 'T-cell': [874], 'lymphoma:': [875], 'common': [876], 'features': [877], 'additional': [879], 'risk': [880], 'factors': [881], 'malignancy.': [883], 'Immunol': [885], '43:': [886], '29–': [887], '37.Medline': [888], 'Kimura': [889], 'Sasazuki': [891], 'T.': [892], 'Eleventh': [894, 913], 'reference': [898], 'protocol': [899], 'HLA-DNA': [902], 'technique.': [904], 'K': [906], 'Tsuki,': [907], 'HLA:': [909], 'Proceedings': [910], 'vol': [919], '397–': [926], '419.': [927], 'Kricka': [928], 'LJ.': [929], 'Miniaturization': [931], 'analytical': [933], 'systems.': [934], 'Clin': [935, 1299], 'Chem': [936], '44(9):': [937], '2008–': [938], '2014.Medline': [939], 'Kruglyak': [940], 'L.': [941, 1285], 'The': [943, 1259, 1345], 'biallelic': [950], 'markers': [951], 'linkage': [953, 976], 'studies.': [954], 'Genet': [956, 1081, 1384], '17(1):': [957], '21–': [958], '24.Medline': [959], 'Lander': [960], 'ES,': [961], 'Botstein': [962], 'D.': [963], '1986.': [964, 1111], 'Strategies': [965], 'studying': [967], 'heterogeneous': [968], 'traits': [970], 'humans': [972], 'using': [974, 1147], 'restriction': [979], 'fragment': [980], 'length': [981], 'polymorphisms.': [982], '83(19):': [988], '7353–': [989], '7357.Medline': [990], 'Lee': [991], 'LG,': [992], 'Connell': [993], 'CR,': [994, 1163], 'Bloch': [995], 'Allelic': [998], 'discrimination': [999], 'nick-translation': [1001], 'PCR': [1002], 'fluorogenic': [1004], 'probes.': [1005, 1352], 'Nucleic': [1006, 1190, 1248, 1364], 'Acids': [1007, 1249, 1365], 'Res': [1008, 1192, 1250, 1366], '21:': [1009, 1251], '3761–': [1010], '3766.Medline': [1011], 'Lipshutz': [1012], 'RJ,': [1013], 'Morris': [1014], 'Chee': [1016], 'Hubbell': [1018], 'Kozal': [1020], 'MJ,': [1021, 1335], 'Shah': [1022], 'Shen': [1024], 'Yang': [1026], 'Fodor': [1028], 'SPA.': [1029], 'Using': [1031], 'assays': [1034], 'access': [1036], 'diversity.': [1038], 'BioTechniques': [1039], '19(3):': [1040], '442–': [1041], '447.Medline': [1042], 'Lucassen': [1043], 'AM,': [1044], 'Julier': [1045], 'Beressi': [1047], 'J-P,': [1048], 'Boitard': [1049], 'Froguel': [1051], 'Bell': [1055], 'JI.': [1056], 'Susceptibility': [1058], 'insulin': [1060, 1075], 'dependent': [1061], 'diabetes': [1062], 'mellitus': [1063], 'maps': [1064], '4.': [1067], '1': [1068], 'Kb': [1069], 'segment': [1070], 'spanning': [1073], 'gene': [1076, 1293], 'associated': [1078], 'VNTR.': [1079], '4:': [1082], '305–': [1083], '310.Medline': [1084], 'Marsh': [1085], 'SGE.': [1086], 'region': [1091], 'sequences,': [1092], 'Tissue': [1094], 'Antigens': [1095], '51:': [1096], '467–': [1097], '507.Medline': [1098], 'Mullis': [1099], 'K,': [1100, 1232, 1313], 'Faloona': [1101], 'F,': [1102, 1228, 1230], 'Scharf': [1103], 'Saiki': [1105], 'Horn': [1107], 'Erlich': [1109], 'Specific': [1112], 'enzymatic': [1113], 'vitro:': [1118], 'reaction.': [1122], 'Cold': [1123], 'Spring': [1124], 'Harb': [1125], 'Symp': [1126], 'Quant': [1127], 'Biol': [1128], '51': [1129], 'Pt': [1130], '1:': [1131], '263–': [1132], '273.Medline': [1133], 'Nevinny-Stickel': [1134], 'Hinzpeter': [1136], 'Andreas': [1138], 'Albert': [1140], 'ED.': [1141], 'Non-radioactive': [1143], 'oligotyping': [1144], 'HLA-DR1-DRw10': [1146], 'reaction,': [1150], 'digoxigenin-labelled': [1151], 'oligonucleotides': [1152, 1212, 1349, 1356], 'chemiluminescence': [1154], 'detection.': [1155, 1216], 'Eur': [1156], 'J': [1157], 'Immunogenet': [1158], '18:': [1159], '323–': [1160], '332.Medline': [1161], 'Newton': [1162], 'Graham': [1164], 'Heptinstall': [1166], 'LE,': [1167], 'Powell': [1168], 'SJ,': [1169], 'Summers': [1170], 'Kalsheker': [1172], 'Smith': [1174], 'JC.': [1175], '1989.': [1176], 'Analysis': [1177], 'any': [1179], 'point': [1180], 'mutation': [1181, 1187], 'DNA:': [1183], 'refractory': [1186], 'system': [1188], '(ARMS).': [1189], 'Acid': [1191], '17:': [1193], '2503–': [1194], '2516.Medline': [1195], 'Nilsson': [1196], 'Malmgren': [1198], 'Samiotaki': [1200], 'Kwiatkowski': [1202], 'Chowdhary': [1204], 'BP,': [1205], 'Landegren': [1206], 'U.': [1207], 'Padlock': [1209], 'probes:': [1210], 'circularizing': [1211], 'localized': [1214], 'Science': [1217, 1268], '265:': [1218], '2085–': [1219], '2088.Medline': [1220], 'Nordhoff': [1221], 'Cramer': [1223], 'Karas': [1225], 'Hillenkamp': [1227], 'Kirpekar': [1229], 'Kristiansen': [1231], 'Roepstorff': [1233], 'P.': [1234], 'Ion': [1236], 'stability': [1237], 'nucleic': [1239], 'acids': [1240], 'infrared': [1242], 'matrix-assisted': [1243], 'laser': [1244], 'desorption/ionization': [1245], 'mass': [1246], 'spectrometry.': [1247], '3347–': [1252], '3357.Medline': [1253], 'Risch': [1254], 'Merikangas': [1256], 'K.': [1257, 1343], 'studies': [1263], 'complex': [1265, 1380], 'diseases.': [1267], '273:': [1269], '1516–': [1270], '1517.Medline': [1271], 'Rosenwasser': [1272], 'LJ,': [1273], 'Klemm': [1274], 'DJ,': [1275], 'Dresback': [1276], 'JK,': [1277], 'Inamura': [1278], 'Mascali': [1280], 'JJ,': [1281], 'Klinnert': [1282], 'Borish': [1284], 'Promoter': [1287], 'polymorphisms': [1288], 'chromosome': [1291], '5': [1292], 'cluster': [1294], 'asthma': [1296], 'atopy.': [1298], 'Exp': [1300], 'Allergy': [1301], '25(Suppl': [1302], '2):': [1303], '74–': [1304], '78,': [1305], '95–96.Medline': [1306], 'Syvänen': [1307], 'A-C,': [1308], 'Aalto-Setälä,': [1309], 'Harju': [1310], 'L,': [1311], 'Kontula': [1312], 'Söderlund': [1314], '1990.': [1316], 'primer-guided': [1318], 'incorporation': [1320], 'genotyping': [1324], 'apoliprotein': [1326], 'E.': [1327], 'Genomics': [1328], '8:': [1329], '684–': [1330], '692.Medline': [1331], 'Wallace': [1332], 'RB,': [1333], 'Johnson': [1334], 'Hirose': [1336], 'T,': [1337, 1339], 'Miyake': [1338], 'Kawashima': [1340], 'EH,': [1341], 'Iyakura': [1342], '1981.': [1344], 'synthetic': [1348], 'as': [1350], 'II.': [1353], 'Hybridization': [1354], 'mixed': [1358], 'rabbit': [1361], 'β-globin': [1362], 'DNA.': [1363], '9:': [1367], '879–': [1368], '894.Medline': [1369], 'Weeks': [1370], 'DE,': [1371], 'GM.': [1373], 'Polygenic': [1375], 'disease:': [1376], 'mapping': [1379], 'Trends': [1383], '11(12):': [1385], '513–': [1386], '519.Medline': [1387], 'Citing': [1388], 'Literature': [1389], 'Volume14,': [1390], 'Issue4October': [1391], '1999Pages': [1392], 'ReferencesRelatedInformation': [1394]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1964698791', 'counts_by_year': [{'year': 2019, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-09T21:44:22.022510', 'created_date': '2016-06-24'}