Publication Information

{'id': 'https://openalex.org/W1964608696', 'doi': 'https://doi.org/10.1300/j069v22n02_05', 'title': 'Use of Very Low-Dose Naltrexone During Opiate Detoxification', 'display_name': 'Use of Very Low-Dose Naltrexone During Opiate Detoxification', 'publication_year': 2003, 'publication_date': '2003-04-01', 'ids': {'openalex': 'https://openalex.org/W1964608696', 'doi': 'https://doi.org/10.1300/j069v22n02_05', 'mag': '1964608696', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12703669'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1300/j069v22n02_05', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S93508928', 'display_name': 'Journal of Addictive Diseases', 'issn_l': '1055-0887', 'issn': ['1055-0887', '1545-0848'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5029310931', 'display_name': 'Paolo Mannelli', 'orcid': 'https://orcid.org/0000-0002-7834-6138'}, 'institutions': [], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Paolo Mannelli', 'raw_affiliation_strings': ["Department of Psychiatry and Human Behavior , Thomas Jefferson University and Istituto di Psichiatria e Psicologia, Unita' di Psichiatria Clinica e Farmacodipendenze, Universita' Cattolica S. Cuore , Rome, Italy"], 'affiliations': [{'raw_affiliation_string': "Department of Psychiatry and Human Behavior , Thomas Jefferson University and Istituto di Psichiatria e Psicologia, Unita' di Psichiatria Clinica e Farmacodipendenze, Universita' Cattolica S. Cuore , Rome, Italy", 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113524601', 'display_name': 'Edward Gottheil', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I149251103', 'display_name': 'Thomas Jefferson University', 'ror': 'https://ror.org/00ysqcn41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I149251103']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Edward Gottheil', 'raw_affiliation_strings': ['Department of Psychiatry and Human Behavior , Thomas Jefferson University'], 'affiliations': [{'raw_affiliation_string': 'Department of Psychiatry and Human Behavior , Thomas Jefferson University', 'institution_ids': ['https://openalex.org/I149251103']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089434190', 'display_name': 'A. Buonanno', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I103320735', 'display_name': 'Università Cattolica del Sacro Cuore', 'ror': 'https://ror.org/03h7r5v07', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I103320735']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Antonio Buonanno', 'raw_affiliation_strings': ["Istituto di Psichiatria e Psicologia, Unita' di Psichiatria Clinica e Farmacodipendenze , Universita' Cattolica S. Cuore , Rome, Italy"], 'affiliations': [{'raw_affiliation_string': "Istituto di Psichiatria e Psicologia, Unita' di Psichiatria Clinica e Farmacodipendenze , Universita' Cattolica S. Cuore , Rome, Italy", 'institution_ids': ['https://openalex.org/I103320735']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5049985069', 'display_name': 'S. De Risio', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I103320735', 'display_name': 'Università Cattolica del Sacro Cuore', 'ror': 'https://ror.org/03h7r5v07', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I103320735']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Sergio De Risio', 'raw_affiliation_strings': ["Istituto di Psichiatria e Psicologia, Unita' di Psichiatria Clinica e Farmacodipendenze , Universita' Cattolica S. Cuore , Rome, Italy"], 'affiliations': [{'raw_affiliation_string': "Istituto di Psichiatria e Psicologia, Unita' di Psichiatria Clinica e Farmacodipendenze , Universita' Cattolica S. Cuore , Rome, Italy", 'institution_ids': ['https://openalex.org/I103320735']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.984, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 18, 'citation_normalized_percentile': {'value': 0.825316, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '22', 'issue': '2', 'first_page': '63', 'last_page': '70'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10576', 'display_name': 'Opioid Use Disorder Treatment', 'score': 0.9627, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10576', 'display_name': 'Opioid Use Disorder Treatment', 'score': 0.9627, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10056', 'display_name': 'Neurotransmitter Receptor Influence on Behavior', 'score': 0.9163, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/detoxification', 'display_name': 'Detoxification', 'score': 0.9156255}, {'id': 'https://openalex.org/keywords/opiate', 'display_name': 'Opiate', 'score': 0.8576964}], 'concepts': [{'id': 'https://openalex.org/C2777972943', 'wikidata': 'https://www.wikidata.org/wiki/Q409587', 'display_name': 'Naltrexone', 'level': 4, 'score': 0.9694899}, {'id': 'https://openalex.org/C2780497538', 'wikidata': 'https://www.wikidata.org/wiki/Q1192006', 'display_name': 'Detoxification (alternative medicine)', 'level': 3, 'score': 0.9156255}, {'id': 'https://openalex.org/C2778140631', 'wikidata': 'https://www.wikidata.org/wiki/Q2026938', 'display_name': 'Opiate', 'level': 3, 'score': 0.8576964}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.53022295}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.44172147}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.42439264}, {'id': 'https://openalex.org/C2781063702', 'wikidata': 'https://www.wikidata.org/wiki/Q427523', 'display_name': 'Opioid', 'level': 3, 'score': 0.2806651}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.20792812}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C204787440', 'wikidata': 'https://www.wikidata.org/wiki/Q188504', 'display_name': 'Alternative medicine', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D009271', 'descriptor_name': 'Naltrexone', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D009271', 'descriptor_name': 'Naltrexone', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': True}, {'descriptor_ui': 'D009292', 'descriptor_name': 'Narcotic Antagonists', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D009292', 'descriptor_name': 'Narcotic Antagonists', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': True}, {'descriptor_ui': 'D009293', 'descriptor_name': 'Opioid-Related Disorders', 'qualifier_ui': 'Q000534', 'qualifier_name': 'rehabilitation', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004334', 'descriptor_name': 'Drug Administration Schedule', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008658', 'descriptor_name': 'Inactivation, Metabolic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008691', 'descriptor_name': 'Methadone', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D008691', 'descriptor_name': 'Methadone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009271', 'descriptor_name': 'Naltrexone', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D009271', 'descriptor_name': 'Naltrexone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009292', 'descriptor_name': 'Narcotic Antagonists', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009294', 'descriptor_name': 'Narcotics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009294', 'descriptor_name': 'Narcotics', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D009293', 'descriptor_name': 'Opioid-Related Disorders', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1300/j069v22n02_05', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S93508928', 'display_name': 'Journal of Addictive Diseases', 'issn_l': '1055-0887', 'issn': ['1055-0887', '1545-0848'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12703669', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.83, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 15, 'referenced_works': ['https://openalex.org/W1514029606', 'https://openalex.org/W1980796138', 'https://openalex.org/W2003566162', 'https://openalex.org/W2012508442', 'https://openalex.org/W2030028793', 'https://openalex.org/W2042480748', 'https://openalex.org/W2052308524', 'https://openalex.org/W2052807439', 'https://openalex.org/W2072203697', 'https://openalex.org/W2097910464', 'https://openalex.org/W2102262969', 'https://openalex.org/W2145092433', 'https://openalex.org/W2159011576', 'https://openalex.org/W2168831889', 'https://openalex.org/W2418790702'], 'related_works': ['https://openalex.org/W3016305297', 'https://openalex.org/W2437708887', 'https://openalex.org/W2416203600', 'https://openalex.org/W2231361550', 'https://openalex.org/W2125939073', 'https://openalex.org/W2124285765', 'https://openalex.org/W2098843949', 'https://openalex.org/W2055915460', 'https://openalex.org/W2028982586', 'https://openalex.org/W1964608696'], 'abstract_inverted_index': {'The': [0], 'use': [1], 'of': [2, 9, 20, 53, 58, 66, 98, 124, 132], 'antagonist': [3], 'drugs': [4], 'to': [5, 73, 92, 115], 'reduce': [6, 116], 'the': [7, 18, 42, 56, 74, 77, 96, 122, 130], 'duration': [8, 120], 'opiate': [10], 'detoxification': [11, 113], 'severely': [12], 'enhances': [13], 'withdrawal': [14, 27, 117], 'symptoms.': [15], 'To': [16], 'investigate': [17], 'feasibility': [19], 'administering': [21], 'antagonists': [22], 'with': [23], 'opiates': [24], 'without': [25, 81, 121], 'intense': [26], 'during': [28], 'detoxification,': [29], '5': [30], 'methadone': [31, 38], 'maintained': [32], 'patients': [33, 88], 'were': [34, 69, 89], 'evaluated': [35], 'while': [36], 'tapering': [37], 'and': [39, 86, 111, 119], 'receiving': [40], 'at': [41], 'same': [43], 'time': [44], 'very': [45, 105], 'low': [46], '(0.125': [47], 'mg),': [48], 'then': [49], 'increasing': [50], 'daily': [51], 'doses': [52], 'naltrexone': [54, 93, 107], 'in': [55], 'course': [57], 'a': [59, 109], '6-day,': [60], 'day': [61, 97], 'hospital': [62], 'treatment.': [63], 'Reduced': [64], 'quantities': [65], 'adjunctive': [67], 'medications': [68], 'administered,': [70], 'as': [71, 127], 'compared': [72], 'standard': [75], 'protocols,': [76], 'treatment': [78], 'was': [79], 'completed': [80], 'incidents': [82], 'or': [83], 'particular': [84], 'discomfort': [85], 'all': [87], 'easily': [90], 'induced': [91], 'maintenance': [94], 'by': [95, 129], 'discharge.': [99], 'Controlled': [100], 'studies': [101], 'will': [102], 'clarify': [103], 'whether': [104], 'low-dose': [106], 'provides': [108], 'safe': [110], 'comfortable': [112], 'technique': [114], 'intensity': [118], 'problems': [123], 'heavy': [125], 'sedation,': [126], 'suggested': [128], 'description': [131], 'these': [133], 'clinical': [134], 'cases.': [135]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1964608696', 'counts_by_year': [{'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 2}], 'updated_date': '2024-12-17T12:39:43.956525', 'created_date': '2016-06-24'}