Title: Bone Disease in Patients With Primary Hypercalciuria and Calcium Nephrolithiasis
Abstract: In patients affected by calcium nephrolithiasis, primary hypercalciuria is frequently accompanied by bone demineralisation and increased susceptibility to fragility fractures. The relationship between bone loss and primary hypercalciuria is multifactorial. Organs and tissues which control calcium and phosphate metabolism – bone, intestine, and kidney – are actively involved in the pathogenesis of bone alterations which together form a multi-factorial metabolic disorder. We conducted a comprehensive evaluation of the published data concerning hypercalciuria and nephrolithiasis included in Medline from 1985 and 2005. In patients affected by calcium nephrolithiasis, primary hypercalciuria is frequently accompanied by bone demineralisation and increased susceptibility to fragility fractures. The relationship between bone loss and primary hypercalciuria is multifactorial. Organs and tissues which control calcium and phosphate metabolism – bone, intestine, and kidney – are actively involved in the pathogenesis of bone alterations which together form a multi-factorial metabolic disorder. We conducted a comprehensive evaluation of the published data concerning hypercalciuria and nephrolithiasis included in Medline from 1985 and 2005.
Publication Year: 2009
Publication Date: 2009-05-10
Language: en
Type: review
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 15
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