Title: IGF‐I treatment of patients with Laron syndrome suppresses serum thrombopoietin levels but does not affect serum erythropoietin
Abstract: American Journal of HematologyVolume 84, Issue 1 p. 64-64 Correspondence and Letters to the EditorFree Access IGF-I treatment of patients with Laron syndrome suppresses serum thrombopoietin levels but does not affect serum erythropoietin† Shevah Orit, Shevah Orit Endocrinology and Diabetes Research Unit, Schneider Children's Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Petah-Tikva, IsraelSearch for more papers by this authorYacobovich Joanne, Yacobovich Joanne Division of Oncology Hematology, Schneider Children's Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Petah-Tikva, IsraelSearch for more papers by this authorZoldan Meira, Zoldan Meira Division of Oncology Hematology, Schneider Children's Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Petah-Tikva, IsraelSearch for more papers by this authorTamary Hannah, Tamary Hannah Division of Oncology Hematology, Schneider Children's Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Petah-Tikva, IsraelSearch for more papers by this authorLaron Zvi, Laron Zvi Endocrinology and Diabetes Research Unit, Schneider Children's Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Petah-Tikva, IsraelSearch for more papers by this author Shevah Orit, Shevah Orit Endocrinology and Diabetes Research Unit, Schneider Children's Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Petah-Tikva, IsraelSearch for more papers by this authorYacobovich Joanne, Yacobovich Joanne Division of Oncology Hematology, Schneider Children's Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Petah-Tikva, IsraelSearch for more papers by this authorZoldan Meira, Zoldan Meira Division of Oncology Hematology, Schneider Children's Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Petah-Tikva, IsraelSearch for more papers by this authorTamary Hannah, Tamary Hannah Division of Oncology Hematology, Schneider Children's Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Petah-Tikva, IsraelSearch for more papers by this authorLaron Zvi, Laron Zvi Endocrinology and Diabetes Research Unit, Schneider Children's Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Petah-Tikva, IsraelSearch for more papers by this author First published: 20 October 2008 https://doi.org/10.1002/ajh.21318Citations: 1 † Conflict of interest: Nothing to report. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article. References 1 Ratajczak J,Zhang Q,Pertusini E, et al. The role of insulin (ONS) and insulin-like growth factor-I (IGF-I) in regulating human erythropoiesis. Studies in vitro under serum-free conditions—Comparison to other cytokines and growth factors. Leukemia 1998; 12: 371– 381. 2 Sivan B,Lilos P,Laron Z. Effects of insulin-like growth factor-I deficiency and replacement therapy on the hematopoietic system in patients with Laron syndrome (primary growth hormone insensitivity). J Pediatr Endocrinol Metab 2003; 16: 509– 520. 3 Merchav S. The haematopoietic effect of growth hormone and insulin-like growth factor I. J Pediatr Endocrinol Metab 1998; 11: 677– 685. 4 Scheding S,Bergmann M,Shimosaka A, et al. Human plasma thrombopoietin levels are regulated by binding to platelet thrombopoietin receptors in vivo. Transfusion 2002; 42: 321– 327. 5 Kling PJ,Taing KM,Dvorak B, et al. Insulin-like growth factor-I stimulates erythropoiesis when administered enterally. Growth Factors 2006; 24: 218– 223. 6 Vihervuori E,Virtanen M,Koistinen H, et al. Hemoglobin level is linked to growth hormone-dependent proteins in short children. Blood 1996; 87: 2075– 2081. 7 Chasis JA,Mohandas N. Erythroblastic islands: Niches for erythropoiesis. Blood 2008; 112: 470– 478. Citing Literature Volume84, Issue1January 2009Pages 64-64 ReferencesRelatedInformation