Title: Chemical characteristics of 99mTc-labeled amine phenols
Abstract: A series of alkylene amine phenols including En(AP)2, Pn(AP)2, DmPn(AP)2, Bn(AP)2 and Pent(AP)2, were synthesized and complexations of the amine phenols with a trace-level 99mTcO4− were undertaken in the presence of Sn2+. The 99mTc-amine phenol complexes obtained were characterized simultaneously by solvent extraction, TLC, electrophoresis and HPLC. The labeling yield, neutrality, lipophilicity and stability of the 99mTc-amine phenol complexes were sufficiently investigated. The chemical behaviors of the complexes of no-carrier-added 99mTc with the amine phenols found in observed study are related to the lengths of hydrocarbon backbones of the ligands.
Publication Year: 1994
Publication Date: 1994-05-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 4
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