Genetic Alterations in MicroRNAs in Medulloblastomas

Name: Work Video:
Duration: 3 min 30 s
Shengqing Lv; Young Ho Kim; Giulio Fiaschetti; Tarek Shalaby; Sumihito Nobusawa; Hui Yang; Zheng Zhou; Michael Grotzer; Hiroko Ohgaki
{'id': 'https://openalex.org/W1947478323', 'doi': 'https://doi.org/10.1111/j.1750-3639.2011.00523.x', 'title': 'Genetic Alterations in MicroRNAs in Medulloblastomas', 'display_name': 'Genetic Alterations in MicroRNAs in Medulloblastomas', 'publication_year': 2011, 'publication_date': '2011-07-27', 'ids': {'openalex': 'https://openalex.org/W1947478323', 'doi': 'https://doi.org/10.1111/j.1750-3639.2011.00523.x', 'mag': '1947478323', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21793975', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/8029025'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1750-3639.2011.00523.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S9094144', 'display_name': 'Brain Pathology', 'issn_l': '1015-6305', 'issn': ['1015-6305', '1750-3639'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8029025', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5015946020', 'display_name': 'Shengqing Lv', 'orcid': 'https://orcid.org/0000-0003-3574-2779'}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Sheng‐Qing Lv', 'raw_affiliation_strings': ["International Agency for Research on Cancer (IARC), Lyon, France Neuro-Oncology Program, University Children's Hospital of Zurich, Switzerland."], 'affiliations': [{'raw_affiliation_string': "International Agency for Research on Cancer (IARC), Lyon, France Neuro-Oncology Program, University Children's Hospital of Zurich, Switzerland.", 'institution_ids': ['https://openalex.org/I42237331']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100335103', 'display_name': 'Young Ho Kim', 'orcid': 'https://orcid.org/0000-0003-0703-1136'}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Young‐Ho Kim', 'raw_affiliation_strings': ['International Agency for Research on Cancer (IARC) Lyon, France.'], 'affiliations': [{'raw_affiliation_string': 'International Agency for Research on Cancer (IARC) Lyon, France.', 'institution_ids': ['https://openalex.org/I42237331']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006495418', 'display_name': 'Giulio Fiaschetti', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1288882113', 'display_name': "Boston Children's Hospital", 'ror': 'https://ror.org/00dvg7y05', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1288882113']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Fiaschetti Giulio', 'raw_affiliation_strings': ["Neuro‐Oncology Program, University Children's Hospital of Zurich, Switzerland"], 'affiliations': [{'raw_affiliation_string': "Neuro‐Oncology Program, University Children's Hospital of Zurich, Switzerland", 'institution_ids': ['https://openalex.org/I1288882113']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110051476', 'display_name': 'Tarek Shalaby', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1288882113', 'display_name': "Boston Children's Hospital", 'ror': 'https://ror.org/00dvg7y05', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1288882113']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Tarek Shalaby', 'raw_affiliation_strings': ["Neuro‐Oncology Program, University Children's Hospital of Zurich, Switzerland"], 'affiliations': [{'raw_affiliation_string': "Neuro‐Oncology Program, University Children's Hospital of Zurich, Switzerland", 'institution_ids': ['https://openalex.org/I1288882113']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051624965', 'display_name': 'Sumihito Nobusawa', 'orcid': 'https://orcid.org/0000-0001-9434-8400'}, 'institutions': [{'id': 'https://openalex.org/I165735259', 'display_name': 'Gunma University', 'ror': 'https://ror.org/046fm7598', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I165735259']}, {'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR', 'JP'], 'is_corresponding': False, 'raw_author_name': 'Sumihito Nobusawa', 'raw_affiliation_strings': ['Department of Pathology, Gunma University, Gunma, Japan', 'International Agency for Research on Cancer (IARC), Lyon, France'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Gunma University, Gunma, Japan', 'institution_ids': ['https://openalex.org/I165735259']}, {'raw_affiliation_string': 'International Agency for Research on Cancer (IARC), Lyon, France', 'institution_ids': ['https://openalex.org/I42237331']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034344782', 'display_name': 'Hui Yang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210117763', 'display_name': 'Xinqiao Hospital', 'ror': 'https://ror.org/02d217z27', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210117763']}, {'id': 'https://openalex.org/I151075929', 'display_name': 'Army Medical University', 'ror': 'https://ror.org/05w21nn13', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I151075929']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hui Yang', 'raw_affiliation_strings': ['Department of Neurosurgery, Xinqiao Hospital, The Third Military Medical University, Chongqing, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurosurgery, Xinqiao Hospital, The Third Military Medical University, Chongqing, China', 'institution_ids': ['https://openalex.org/I4210117763', 'https://openalex.org/I151075929']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086011032', 'display_name': 'Zheng Zhou', 'orcid': 'https://orcid.org/0000-0003-3397-3290'}, 'institutions': [{'id': 'https://openalex.org/I4210117763', 'display_name': 'Xinqiao Hospital', 'ror': 'https://ror.org/02d217z27', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210117763']}, {'id': 'https://openalex.org/I151075929', 'display_name': 'Army Medical University', 'ror': 'https://ror.org/05w21nn13', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I151075929']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zheng Zhou', 'raw_affiliation_strings': ['Department of Neurosurgery, Xinqiao Hospital, The Third Military Medical University, Chongqing, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurosurgery, Xinqiao Hospital, The Third Military Medical University, Chongqing, China', 'institution_ids': ['https://openalex.org/I4210117763', 'https://openalex.org/I151075929']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020920424', 'display_name': 'Michael Grotzer', 'orcid': 'https://orcid.org/0000-0002-1154-2732'}, 'institutions': [{'id': 'https://openalex.org/I1288882113', 'display_name': "Boston Children's Hospital", 'ror': 'https://ror.org/00dvg7y05', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1288882113']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Michael Grotzer', 'raw_affiliation_strings': ["Neuro‐Oncology Program, University Children's Hospital of Zurich, Switzerland"], 'affiliations': [{'raw_affiliation_string': "Neuro‐Oncology Program, University Children's Hospital of Zurich, Switzerland", 'institution_ids': ['https://openalex.org/I1288882113']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5103530823', 'display_name': 'Hiroko Ohgaki', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Hiroko Ohgaki', 'raw_affiliation_strings': ['International Agency for Research on Cancer (IARC) Lyon, France.'], 'affiliations': [{'raw_affiliation_string': 'International Agency for Research on Cancer (IARC) Lyon, France.', 'institution_ids': ['https://openalex.org/I42237331']}]}], 'institution_assertions': [], 'countries_distinct_count': 4, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3500, 'currency': 'USD', 'value_usd': 3500, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.538, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 52, 'citation_normalized_percentile': {'value': 0.870128, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '22', 'issue': '2', 'first_page': '230', 'last_page': '239'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA in disease regulation', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA in disease regulation', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11765', 'display_name': 'Circular RNAs in diseases', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10515', 'display_name': 'Cancer-related molecular mechanisms research', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C145059251', 'wikidata': 'https://www.wikidata.org/wiki/Q310899', 'display_name': 'microRNA', 'level': 3, 'score': 0.7533722}, {'id': 'https://openalex.org/C173396325', 'wikidata': 'https://www.wikidata.org/wiki/Q1501275', 'display_name': 'Gene knockdown', 'level': 3, 'score': 0.7507061}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.72694814}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.6432947}, {'id': 'https://openalex.org/C127561419', 'wikidata': 'https://www.wikidata.org/wiki/Q224527', 'display_name': 'Downregulation and upregulation', 'level': 3, 'score': 0.58934873}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.5483587}, {'id': 'https://openalex.org/C501734568', 'wikidata': 'https://www.wikidata.org/wiki/Q42918', 'display_name': 'Mutation', 'level': 3, 'score': 0.532776}, {'id': 'https://openalex.org/C119056186', 'wikidata': 'https://www.wikidata.org/wiki/Q1431332', 'display_name': 'Gene silencing', 'level': 3, 'score': 0.5015373}, {'id': 'https://openalex.org/C89604277', 'wikidata': 'https://www.wikidata.org/wiki/Q424345', 'display_name': 'Untranslated region', 'level': 4, 'score': 0.4285405}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.41630274}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.39405864}, {'id': 'https://openalex.org/C105580179', 'wikidata': 'https://www.wikidata.org/wiki/Q188928', 'display_name': 'Messenger RNA', 'level': 3, 'score': 0.30723763}], 'mesh': [{'descriptor_ui': 'D002528', 'descriptor_name': 'Cerebellar Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D020022', 'descriptor_name': 'Genetic Predisposition to Disease', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D008527', 'descriptor_name': 'Medulloblastoma', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002528', 'descriptor_name': 'Cerebellar Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002675', 'descriptor_name': 'Child, Preschool', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005784', 'descriptor_name': 'Gene Amplification', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D005784', 'descriptor_name': 'Gene Amplification', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017353', 'descriptor_name': 'Gene Deletion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020022', 'descriptor_name': 'Genetic Predisposition to Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005820', 'descriptor_name': 'Genetic Testing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D057809', 'descriptor_name': 'HEK293 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006367', 'descriptor_name': 'HeLa Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007223', 'descriptor_name': 'Infant', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008527', 'descriptor_name': 'Medulloblastoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016271', 'descriptor_name': 'Proto-Oncogene Proteins c-myc', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D016271', 'descriptor_name': 'Proto-Oncogene Proteins c-myc', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055815', 'descriptor_name': 'Young Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1750-3639.2011.00523.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S9094144', 'display_name': 'Brain Pathology', 'issn_l': '1015-6305', 'issn': ['1015-6305', '1750-3639'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8029025', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21793975', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8029025', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 45, 'referenced_works': ['https://openalex.org/W112404563', 'https://openalex.org/W144423133', 'https://openalex.org/W1653566857', 'https://openalex.org/W1765636564', 'https://openalex.org/W1783699960', 'https://openalex.org/W1967342065', 'https://openalex.org/W1977376661', 'https://openalex.org/W1984214021', 'https://openalex.org/W1995541594', 'https://openalex.org/W1997716191', 'https://openalex.org/W2007920048', 'https://openalex.org/W2014946489', 'https://openalex.org/W2017068782', 'https://openalex.org/W2018776569', 'https://openalex.org/W2020301883', 'https://openalex.org/W2034194437', 'https://openalex.org/W2035760017', 'https://openalex.org/W2037631027', 'https://openalex.org/W2041140837', 'https://openalex.org/W2056940627', 'https://openalex.org/W2058290860', 'https://openalex.org/W2062151342', 'https://openalex.org/W2070264387', 'https://openalex.org/W2073840747', 'https://openalex.org/W2077068179', 'https://openalex.org/W2087010810', 'https://openalex.org/W2087056964', 'https://openalex.org/W2107277218', 'https://openalex.org/W2109712459', 'https://openalex.org/W2112495947', 'https://openalex.org/W2129461451', 'https://openalex.org/W2134816104', 'https://openalex.org/W2135314242', 'https://openalex.org/W2139787372', 'https://openalex.org/W2141915880', 'https://openalex.org/W2145352784', 'https://openalex.org/W2150536104', 'https://openalex.org/W2152735985', 'https://openalex.org/W2156239357', 'https://openalex.org/W2156757280', 'https://openalex.org/W2158671377', 'https://openalex.org/W2160102037', 'https://openalex.org/W23556053', 'https://openalex.org/W2624094894', 'https://openalex.org/W4388242592'], 'related_works': ['https://openalex.org/W4247833810', 'https://openalex.org/W4242240318', 'https://openalex.org/W4213065871', 'https://openalex.org/W3127487613', 'https://openalex.org/W3103789129', 'https://openalex.org/W3048105303', 'https://openalex.org/W2904239912', 'https://openalex.org/W2375617144', 'https://openalex.org/W2041761948', 'https://openalex.org/W2026936876'], 'abstract_inverted_index': {'MicroRNAs': [0], '(miRNAs)': [1], 'regulate': [2], 'a': [3, 83, 118], 'variety': [4], 'of': [5, 11, 24, 34, 37, 45, 93, 111, 132, 136, 142, 153, 166, 172], 'cellular': [6], 'processes': [7], 'via': [8], 'the': [9, 32, 35, 42, 46, 86, 164, 170, 180, 189], 'regulation': [10], 'multiple': [12], 'target': [13, 39], 'genes.': [14], 'We': [15], 'screened': [16], '48': [17], 'medulloblastomas': [18, 98], 'for': [19], 'mutation,': [20], 'deletion': [21, 67, 126], 'and': [22, 62, 75, 115, 123, 147], 'amplification': [23, 69, 81], 'nine': [25], 'miRNA': [26, 88, 190], 'genes': [27, 191], 'that': [28, 177, 186], 'were': [29, 89], 'selected': [30], 'on': [31], 'basis': [33], 'presence': [36], 'potential': [38], 'sequences': [40], 'within': [41], "3'-untranslated": [43], 'region': [44], 'MYCC': [47, 107, 121, 143, 167, 181, 199], 'mRNA.': [48], 'Differential': [49], 'PCR': [50], 'revealed': [51, 106], 'deletions': [52], 'in': [53, 72, 91, 109, 139, 145, 155, 163, 188, 201], 'miR-186': [54], '(15%),': [55], 'miR-135a-1': [56], '(33%),': [57], 'miR-548d-1': [58], '(42%),': [59], 'miR-548d-2': [60], '(21%)': [61], 'miR-512-2': [63, 124, 154, 178], '(33%)': [64], 'genes,': [65], 'whereas': [66], 'or': [68, 82], 'was': [70, 117], 'detected': [71, 90], 'miR-135b': [73], '(23%)': [74], 'miR-135a-2': [76], '(15%).': [77], 'In': [78], 'miR-33b,': [79], 'deletion,': [80], 'mutation': [84], 'at': [85, 100], 'precursor': [87], '10%': [92], 'medulloblastomas.': [94, 202], 'Overall,': [95], '35/48': [96], '(73%)': [97], 'had': [99], 'least': [101], 'one': [102], 'alteration.': [103], 'Real-time': [104], 'RT-PCR': [105], 'overexpression': [108, 122, 152, 200], '11': [110], '37': [112], '(30%)': [113], 'medulloblastomas,': [114], 'there': [116], 'correlation': [119], 'between': [120], 'gene': [125], '(P': [127], '=': [128], '0.0084).': [129], 'Antisense-based': [130], 'knockdown': [131], 'miR-512-5p': [133], '(mature': [134], 'sequence': [135], 'miR-512-2)': [137], 'resulted': [138, 162], 'significant': [140], 'upregulation': [141], 'expression': [144], 'HeLa': [146], 'A549': [148], 'cells,': [149], 'while': [150], 'forced': [151], 'medulloblastoma/PNET': [156], 'cell': [157], 'lines': [158], 'DAOY,': [159], 'UW-228-2,': [160], 'PFSK': [161], 'downregulation': [165], 'protein.': [168], 'Furthermore,': [169], 'results': [171, 184], 'luciferase': [173], 'reporter': [174], 'assays': [175], 'suggested': [176], 'targets': [179], 'gene.': [182], 'These': [183], 'suggest': [185], 'alterations': [187], 'may': [192], 'be': [193], 'an': [194], 'alternative': [195], 'mechanism': [196], 'leading': [197], 'to': [198]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1947478323', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 9}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 8}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2024-12-24T16:12:14.130860', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
