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'tobacco': [20], 'smoking': [21, 100, 276], 'alcohol': [23, 102], 'consumption.': [24], 'Epidermal': [25], 'growth': [26], 'factor': [27, 72], 'receptor': [28], '(EGFR)': [29], 'a': [31, 96, 272], 'member': [32], 'of': [33, 43, 60, 99, 126, 142, 239, 257], 'Type': [34], 'I': [35], 'tyrosine': [36, 204], 'kinases.': [37], 'Its': [38], 'activation': [39, 238], 'causes': [40], 'docking': [42], 'various': [44, 83], 'proteins': [45], 'in': [46, 82, 176, 214, 268, 271], 'its': [47, 207, 242], 'cytosolic': [48], 'tail.': [49], 'In': [50], 'present': [52], 'study': [53], 'we': [54], 'have': [55], 'analyzed': [56, 121, 132], 'expression': [58, 128], 'pattern': [59], 'EGFR,': [61], 'protein': [62], 'kinase': [63], 'C': [64], 'δ': [65], '(PKCδ),': [66], 'tumor': [67], 'necrosis': [68], 'factor‐α': [69], '(TNF‐α),': [70], 'nuclear': [71], 'κB': [73], '(NFκB)': [74], 'interactions': [77], 'between': [78, 147, 171], 'EGFR': [79, 127, 143, 203, 240], 'PKCδ': [81, 210, 246], 'pathological': [84, 118], 'conditions.': [85], 'Methods:': [86], 'Human': [87], 'esophageal': [88, 259], 'biopsies': [89], 'were': [90, 120], 'obtained': [91], 'from': [92], '93': [93], 'patients': [94], 'past': [97], 'history': [98], 'consumption:': [103], '20': [104], 'showed': [105], 'normal': [106, 258, 269], 'mucosa,': [107], '40': [108], 'dysplasia': [110, 151, 172], '33': [112], 'squamous': [113], 'cell': [114], 'carcinoma': [115, 153], '(SCC).': [116], 'These': [117], 'conditions': [119, 249], 'immunohistochemically': [122], 'for': [123], 'presence': [125], 'then': [130], 'subsequently': [131], 'using': [133], 'immunoblot': [134], 'immunoprecipitation.': [136], 'Results:': [137], 'A': [138, 166], 'statistically': [139], 'significant': [140], 'difference': [141], 'overexpression': [144], 'was': [145, 169, 211], 'found': [146], 'low‐': [148], 'high‐grade': [150], '(χ': [154, 180], '2': [155, 159, 181, 185, 196, 220], '=': [156, 160, 163, 182, 186, 192, 197, 221, 229], '3.3,': [157], 'χ': [158, 184, 195, 219], '3.42:': [161], 'P': [162, 188, 191, 200, 223, 228], '0.07,': [164], '0.33).': [165], 'statistical': [167], 'significance': [168], 'observed': [170], 'SCC': [174], 'all': [177, 215], 'histopathological': [178, 216], 'types': [179, 217], '4,': [183], '4.9;': [187], '<': [189, 201, 224], '0.05,': [190], '0.18': [193], '26.3,': [198], '26.6;': [199], '0.001).': [202], 'phosphorylation': [205], 'association': [208], 'significantly': [212], 'higher': [213], '7.965;': [222], '0.05': [225], '4.0830;': [227], '0.2530.': [230], 'Conclusion:': [231], 'Altogether,': [232], 'our': [233], 'findings': [234], 'reveal': [235], 'that': [236], 'subsequent': [243], 'interaction': [244], 'under': [247], 'inflammatory': [248], 'might': [250], 'positively': [251], 'be': [252], 'attributed': [253], 'to': [254, 261, 275], 'transformation': [256], 'epithelia': [260], 'SCC,': [262], 'which': [263], 'could': [264], 'explain': [265], 'ongoing': [266], 'inflammation': [267], 'mucosa': [270], 'population': [273], 'prone': [274], 'alcoholism.': [278]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1944835045', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 2}], 'updated_date': '2024-08-15T03:28:28.246534', 'created_date': '2016-06-24'}