Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1944404325', 'doi': 'https://doi.org/10.1242/dev.125.12.2203', 'title': 'Combinatorial <i>Gli</i> gene function in floor plate and neuronal inductions by Sonic hedgehog', 'display_name': 'Combinatorial <i>Gli</i> gene function in floor plate and neuronal inductions by Sonic hedgehog', 'publication_year': 1998, 'publication_date': '1998-06-15', 'ids': {'openalex': 'https://openalex.org/W1944404325', 'doi': 'https://doi.org/10.1242/dev.125.12.2203', 'mag': '1944404325', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9584120'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1242/dev.125.12.2203', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S86558740', 'display_name': 'Development', 'issn_l': '0950-1991', 'issn': ['0950-1991', '1477-9129'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5076834474', 'display_name': 'Ariel Ruiz i Altaba', 'orcid': 'https://orcid.org/0000-0003-2292-3933'}, 'institutions': [{'id': 'https://openalex.org/I4210086933', 'display_name': 'NYU Langone Health', 'ror': 'https://ror.org/005dvqh91', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210086933']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'A. Ruiz i Altaba', 'raw_affiliation_strings': ['The Skirball Institute, Developmental Genetics Program and Department of Cell Biology, NYU Medical Center, 540 First Avenue, New York, NY 10016, USA'], 'affiliations': [{'raw_affiliation_string': 'The Skirball Institute, Developmental Genetics Program and Department of Cell Biology, NYU Medical Center, 540 First Avenue, New York, NY 10016, USA', 'institution_ids': ['https://openalex.org/I4210086933']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5076834474'], 'corresponding_institution_ids': ['https://openalex.org/I4210086933'], 'apc_list': None, 'apc_paid': None, 'fwci': 6.214, 'has_fulltext': False, 'cited_by_count': 243, 'citation_normalized_percentile': {'value': 0.95839, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '125', 'issue': '12', 'first_page': '2203', 'last_page': '2212'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12009', 'display_name': 'Hedgehog Signaling Pathway Studies', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12009', 'display_name': 'Hedgehog Signaling Pathway Studies', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10268', 'display_name': 'Developmental Biology and Gene Regulation', 'score': 0.9968, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12061', 'display_name': 'Axon Guidance and Neuronal Signaling', 'score': 0.9492, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/gli2', 'display_name': 'GLI2', 'score': 0.96495694}, {'id': 'https://openalex.org/keywords/gli3', 'display_name': 'GLI3', 'score': 0.94873}, {'id': 'https://openalex.org/keywords/gli1', 'display_name': 'GLI1', 'score': 0.9371296}, {'id': 'https://openalex.org/keywords/floor-plate', 'display_name': 'Floor plate', 'score': 0.8192072}], 'concepts': [{'id': 'https://openalex.org/C120407494', 'wikidata': 'https://www.wikidata.org/wiki/Q14886491', 'display_name': 'GLI2', 'level': 4, 'score': 0.96495694}, {'id': 'https://openalex.org/C97182474', 'wikidata': 'https://www.wikidata.org/wiki/Q14886904', 'display_name': 'GLI3', 'level': 5, 'score': 0.94873}, {'id': 'https://openalex.org/C2779933373', 'wikidata': 'https://www.wikidata.org/wiki/Q14886430', 'display_name': 'GLI1', 'level': 4, 'score': 0.9371296}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.8355402}, {'id': 'https://openalex.org/C78577261', 'wikidata': 'https://www.wikidata.org/wiki/Q3391691', 'display_name': 'Floor plate', 'level': 2, 'score': 0.8192072}, {'id': 'https://openalex.org/C2776637008', 'wikidata': 'https://www.wikidata.org/wiki/Q14860072', 'display_name': 'Sonic hedgehog', 'level': 3, 'score': 0.7688815}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.58898795}, {'id': 'https://openalex.org/C121587040', 'wikidata': 'https://www.wikidata.org/wiki/Q898769', 'display_name': 'Homeobox', 'level': 4, 'score': 0.5278896}, {'id': 'https://openalex.org/C88498014', 'wikidata': 'https://www.wikidata.org/wiki/Q14859918', 'display_name': 'Hedgehog signaling pathway', 'level': 3, 'score': 0.5228527}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.4824746}, {'id': 'https://openalex.org/C2778539099', 'wikidata': 'https://www.wikidata.org/wiki/Q6120', 'display_name': 'Hedgehog', 'level': 3, 'score': 0.46819767}, {'id': 'https://openalex.org/C24284526', 'wikidata': 'https://www.wikidata.org/wiki/Q204785', 'display_name': 'Zinc finger', 'level': 4, 'score': 0.46079522}, {'id': 'https://openalex.org/C148738053', 'wikidata': 'https://www.wikidata.org/wiki/Q210861', 'display_name': 'Cellular differentiation', 'level': 3, 'score': 0.43332776}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.38595876}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.27880567}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.25371093}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.2345722}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.18584919}, {'id': 'https://openalex.org/C158448853', 'wikidata': 'https://www.wikidata.org/wiki/Q425218', 'display_name': 'Repressor', 'level': 4, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D019521', 'descriptor_name': 'Body Patterning', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D002490', 'descriptor_name': 'Central Nervous System', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': True}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D004627', 'descriptor_name': 'Embryonic Induction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009419', 'descriptor_name': 'Nerve Tissue Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D015513', 'descriptor_name': 'Oncogene Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D012097', 'descriptor_name': 'Repressor Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D015534', 'descriptor_name': 'Trans-Activators', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D029867', 'descriptor_name': 'Xenopus Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002454', 'descriptor_name': 'Cell Differentiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002490', 'descriptor_name': 'Central Nervous System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D018507', 'descriptor_name': 'Gene Expression Regulation, Developmental', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053823', 'descriptor_name': 'Hedgehog Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051741', 'descriptor_name': 'Kruppel-Like Transcription Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009046', 'descriptor_name': 'Motor Neurons', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D009046', 'descriptor_name': 'Motor Neurons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015513', 'descriptor_name': 'Oncogene Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015513', 'descriptor_name': 'Oncogene Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016548', 'descriptor_name': 'Prosencephalon', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': False}, {'descriptor_ui': 'D016548', 'descriptor_name': 'Prosencephalon', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013116', 'descriptor_name': 'Spinal Cord', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': False}, {'descriptor_ui': 'D013116', 'descriptor_name': 'Spinal Cord', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000074482', 'descriptor_name': 'Thyroid Nuclear Factor 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D014982', 'descriptor_name': 'Xenopus laevis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000071676', 'descriptor_name': 'Zinc Finger Protein GLI1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000075746', 'descriptor_name': 'Zinc Finger Protein Gli2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000074290', 'descriptor_name': 'Zinc Finger Protein Gli3', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1242/dev.125.12.2203', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S86558740', 'display_name': 'Development', 'issn_l': '0950-1991', 'issn': ['0950-1991', '1477-9129'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9584120', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 60, 'referenced_works': ['https://openalex.org/W1553444759', 'https://openalex.org/W1589859980', 'https://openalex.org/W1592555477', 'https://openalex.org/W1785629757', 'https://openalex.org/W1844026860', 'https://openalex.org/W1895875855', 'https://openalex.org/W1901208108', 'https://openalex.org/W1966088902', 'https://openalex.org/W1970642341', 'https://openalex.org/W1971103607', 'https://openalex.org/W1982087641', 'https://openalex.org/W1984379066', 'https://openalex.org/W1987366641', 'https://openalex.org/W1990542926', 'https://openalex.org/W1992865216', 'https://openalex.org/W1998931558', 'https://openalex.org/W2003762489', 'https://openalex.org/W2005462392', 'https://openalex.org/W2007535582', 'https://openalex.org/W2010206624', 'https://openalex.org/W2012199249', 'https://openalex.org/W2014364643', 'https://openalex.org/W2017204222', 'https://openalex.org/W2019150363', 'https://openalex.org/W2021103771', 'https://openalex.org/W2022031300', 'https://openalex.org/W2025963445', 'https://openalex.org/W2031502549', 'https://openalex.org/W2032205265', 'https://openalex.org/W2040773128', 'https://openalex.org/W2045947221', 'https://openalex.org/W2047457815', 'https://openalex.org/W2048083836', 'https://openalex.org/W2051543667', 'https://openalex.org/W2053577848', 'https://openalex.org/W2059614045', 'https://openalex.org/W2060505600', 'https://openalex.org/W2064941027', 'https://openalex.org/W2073288043', 'https://openalex.org/W2077802746', 'https://openalex.org/W2081467390', 'https://openalex.org/W2088010633', 'https://openalex.org/W2090204791', 'https://openalex.org/W2094579915', 'https://openalex.org/W2096548029', 'https://openalex.org/W2097888799', 'https://openalex.org/W2099118069', 'https://openalex.org/W2102372298', 'https://openalex.org/W2105180222', 'https://openalex.org/W2111546844', 'https://openalex.org/W2132008353', 'https://openalex.org/W2138526982', 'https://openalex.org/W2138979073', 'https://openalex.org/W2140654443', 'https://openalex.org/W2149031125', 'https://openalex.org/W2156086003', 'https://openalex.org/W2208796000', 'https://openalex.org/W2328269288', 'https://openalex.org/W2343053880', 'https://openalex.org/W4285719527'], 'related_works': ['https://openalex.org/W2100564455', 'https://openalex.org/W2099118069', 'https://openalex.org/W2075309963', 'https://openalex.org/W2074863882', 'https://openalex.org/W2012912580', 'https://openalex.org/W2011564568', 'https://openalex.org/W1964929288', 'https://openalex.org/W1950508909', 'https://openalex.org/W1944404325', 'https://openalex.org/W1676048097'], 'abstract_inverted_index': {'ABSTRACT': [0], 'Within': [1], 'the': [2, 15, 24, 45, 54, 67, 83, 88, 116, 128, 149, 159, 194, 202, 218, 222, 242, 252, 287], 'developing': [3], 'vertebrate': [4], 'nervous': [5], 'system,': [6], 'it': [7, 91, 210], 'is': [8, 60, 92, 105, 211, 215], 'not': [9], 'known': [10], 'how': [11, 23], 'progenitor': [12], 'cells': [13, 32, 64, 134, 192], 'interpret': [14], 'positional': [16, 291], 'information': [17, 292], 'provided': [18], 'by': [19, 135, 158, 176, 186, 251, 270, 279], 'inducing': [20, 71], 'signals': [21], 'or': [22], 'domains': [25], 'in': [26, 41, 62, 137], 'which': [27], 'distinct': [28], 'groups': [29], 'of': [30, 69, 108, 118, 131, 148, 162, 220, 244, 267], 'neural': [31, 47, 84, 288], 'differentiate': [33], 'are': [34, 80, 174], 'defined.': [35], 'Gli': [36, 203, 223, 256, 283], 'proteins': [37, 224], 'may': [38, 285], 'be': [39, 156, 249], 'involved': [40], 'these': [42, 178], 'processes.': [43], 'In': [44, 75, 122, 240, 272], 'frog': [46], 'plate,': [48], 'we': [49], 'have': [50, 197], 'previously': [51, 199], 'shown': [52, 93, 200, 212], 'that': [53, 94, 188, 201, 213, 262], 'zinc': [55], 'finger': [56], 'transcription': [57], 'factor': [58], 'Gli1': [59, 113, 136, 167, 171, 227, 258], 'expressed': [61, 81, 255], 'midline': [63], 'and': [65, 78, 96, 125, 140, 164, 172, 208, 235, 259, 293], 'mediates': [66, 265], 'effects': [68], 'Shh': [70, 97, 109, 187], 'floor': [72, 119, 132, 143, 150, 190], 'plate': [73, 85, 120, 133, 144, 151, 191], 'differentiation.': [74, 145, 239, 296], 'contrast,': [76, 241], 'Gli2': [77, 124, 163, 173, 234, 263], 'Gli3': [79, 95, 126, 165, 236, 274], 'throughout': [82], 'except': [86], 'for': [87], 'midline.': [89, 195], 'Here,': [90], 'repress': [98, 127], 'each': [99], 'other': [100], 'whereas': [101], 'Gli2,': [102, 260], 'like': [103], 'Gli1,': [104], 'a': [106, 181], 'target': [107], 'signaling.': [110], 'However,': [111], 'only': [112], 'can': [114, 248], 'induce': [115, 205], 'differentiation': [117, 207, 243, 278], 'cells.': [121], 'addition,': [123, 273], 'ectopic': [129], 'induction': [130, 266], 'co-injection': [138], 'assays': [139], 'inhibit': [141, 237], 'endogenous': [142], 'The': [146], 'definition': [147], 'domain,': [152], 'therefore,': [153], 'appears': [154], 'to': [155, 193, 217], 'defined': [157], 'antagonizing': [160], 'activities': [161], 'on': [166], 'function.': [168], 'Because': [169], 'both': [170], 'induced': [175, 250], 'Shh,': [177], 'results': [179], 'establish': [180], 'regulatory': [182], 'feedback': [183], 'loop': [184], 'triggered': [185], 'restricts': [189], 'We': [196], 'also': [198], 'genes': [204], 'neuronal': [206], 'here': [209], 'there': [214], 'specificity': [216], 'types': [219], 'neurons': [221, 247, 269], 'induce.': [225], 'Only': [226], 'induces': [228], 'Nkx2.1/TTF-1+': [229], 'ventral': [230], 'forebrain': [231], 'neurons.': [232], 'Moreover,': [233], 'their': [238], 'spinal': [245], 'motor': [246, 268, 276], 'two': [253], 'ventrally': [254], 'genes,': [257], 'suggesting': [261], 'directly': [264], 'Shh.': [271], 'inhibits': [275], 'neuron': [277], 'Gli2.': [280], 'Thus,': [281], 'combinatorial': [282], 'function': [284], 'pattern': [286], 'tube,': [289], 'integrating': [290], 'cell': [294], 'type': [295]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1944404325', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 10}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 9}, {'year': 2012, 'cited_by_count': 11}], 'updated_date': '2025-01-08T02:10:52.904494', 'created_date': '2016-06-24'}