Title: Chronic haemolytic anaemia because of pyruvate kinase (PK) deficiency in a child heterozygous for haemoglobin S and no clinical features of sickle cell disease
Abstract: European Journal of HaematologyVolume 84, Issue 1 p. 89-90 Chronic haemolytic anaemia because of pyruvate kinase (PK) deficiency in a child heterozygous for haemoglobin S and no clinical features of sickle cell disease Licínio Manco, Licínio Manco Departamento de Hematologia, Centro Hospitalar de Coimbra, Coimbra Departamento de Antropologia/CIAS, Universidade de Coimbra, Coimbra, PortugalSearch for more papers by this authorJosé Manuel Vagace, José Manuel Vagace Servicio de Hematología, Hospital Materno Infantil, Badajoz EspanaSearch for more papers by this authorLuís Relvas, Luís Relvas Departamento de Hematologia, Centro Hospitalar de Coimbra, CoimbraSearch for more papers by this authorUmbelina Rebelo, Umbelina Rebelo Departamento de Hematologia, Centro Hospitalar de Coimbra, CoimbraSearch for more papers by this authorCeleste Bento, Celeste Bento Departamento de Hematologia, Centro Hospitalar de Coimbra, CoimbraSearch for more papers by this authorAna Villegas, Ana Villegas Servicio de Hematología, Hospital Clínico San Carlos, Madrid, EspañaSearch for more papers by this authorMaria Letícia Ribeiro, Maria Letícia Ribeiro Departamento de Hematologia, Centro Hospitalar de Coimbra, CoimbraSearch for more papers by this author Licínio Manco, Licínio Manco Departamento de Hematologia, Centro Hospitalar de Coimbra, Coimbra Departamento de Antropologia/CIAS, Universidade de Coimbra, Coimbra, PortugalSearch for more papers by this authorJosé Manuel Vagace, José Manuel Vagace Servicio de Hematología, Hospital Materno Infantil, Badajoz EspanaSearch for more papers by this authorLuís Relvas, Luís Relvas Departamento de Hematologia, Centro Hospitalar de Coimbra, CoimbraSearch for more papers by this authorUmbelina Rebelo, Umbelina Rebelo Departamento de Hematologia, Centro Hospitalar de Coimbra, CoimbraSearch for more papers by this authorCeleste Bento, Celeste Bento Departamento de Hematologia, Centro Hospitalar de Coimbra, CoimbraSearch for more papers by this authorAna Villegas, Ana Villegas Servicio de Hematología, Hospital Clínico San Carlos, Madrid, EspañaSearch for more papers by this authorMaria Letícia Ribeiro, Maria Letícia Ribeiro Departamento de Hematologia, Centro Hospitalar de Coimbra, CoimbraSearch for more papers by this author First published: 11 December 2009 https://doi.org/10.1111/j.1600-0609.2009.01353.xCitations: 1 Licínio Manco, Unidade de Hematologia Molecular, Departamento de Hematologia, Centro Hospitalar de Coimbra, 3000 Coimbra, Portugal. Tel: +351-239-480370; Fax: +351-239-717216; e-mail: [email protected] Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References 1 Zanella A, Fermo E, Bianchi P, Chiarelli LR, Valentini G. Pyruvate kinase deficiency: the genotype-phenotype association. Blood Rev 2007; 21: 217–31. 2 Cohen-Solal M, Préhu C, Wajcman H, Poyart C, Bardakdjian-Michau J, Kister J, Promé D, Valentin C, Bachir D, Galactéros F. A new sickle cell disease phenotype associating Hb S trait, severe pyruvate kinase deficiency (PK Conakry), and an alpha2 globin gene variant (Hb Conakry). Br J Haematol 1998; 103: 950–6. 3 Alli N, Coetzee M, Louw V, Van Rensburg B, Rossouw G, Thompson L, Pissard S, Thein SL. Sickle cell disease in a carrier with pyruvate kinase deficiency. Hematology 2008; 13: 369–72. 4 Dacie JV, Lewis SM. Practical Haematology. 8th edn. London: Churchill Livingstone, 2001. 5 Beutler E, Blume KG, Kaplan JC, Löhr GW, Ramot B, Valentine WN. International Committee for Standardization in Haematology: recommended methods for red-cell enzyme analysis. Br J Haematol 1977; 35: 331–40. 6 Lichtman MA, Murphy MS, Adamson JW. Detection of mutant hemoglobins with altered affinity for oxygen. A simplified technique. Ann Intern Med 1976; 84: 517–20. 7 Zanella A, Fermo E, Bianchi P, Valentini G. Red cell pyruvate kinase deficiency: molecular and clinical aspects. Br J Haematol 2005; 130: 11–25. Citing Literature Volume84, Issue1January 2010Pages 89-90 ReferencesRelatedInformation