Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1935073111', 'doi': 'https://doi.org/10.18632/oncotarget.3416', 'title': 'Metastasis-associated in colon cancer-1 promotes vasculogenic mimicry in gastric cancer by upregulating TWIST1/2', 'display_name': 'Metastasis-associated in colon cancer-1 promotes vasculogenic mimicry in gastric cancer by upregulating TWIST1/2', 'publication_year': 2015, 'publication_date': '2015-03-20', 'ids': {'openalex': 'https://openalex.org/W1935073111', 'doi': 'https://doi.org/10.18632/oncotarget.3416', 'mag': '1935073111', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25895023', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4484471'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.3416', 'pdf_url': 'https://www.oncotarget.com/article/3416/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.oncotarget.com/article/3416/pdf/', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100403178', 'display_name': 'Lin Wang', 'orcid': 'https://orcid.org/0000-0002-5980-0112'}, 'institutions': [{'id': 'https://openalex.org/I4210103346', 'display_name': 'Nanfang Hospital', 'ror': 'https://ror.org/01eq10738', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210103346']}, {'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lin Wang', 'raw_affiliation_strings': ['Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China', 'institution_ids': ['https://openalex.org/I4210103346', 'https://openalex.org/I58200834']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100381421', 'display_name': 'Lin Li', 'orcid': 'https://orcid.org/0000-0002-9719-4539'}, 'institutions': [{'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}, {'id': 'https://openalex.org/I4210103346', 'display_name': 'Nanfang Hospital', 'ror': 'https://ror.org/01eq10738', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210103346']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Li Lin', 'raw_affiliation_strings': ['Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China', 'institution_ids': ['https://openalex.org/I58200834', 'https://openalex.org/I4210103346']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100330005', 'display_name': 'Xi Chen', 'orcid': 'https://orcid.org/0000-0002-9835-7141'}, 'institutions': [{'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}, {'id': 'https://openalex.org/I4210103346', 'display_name': 'Nanfang Hospital', 'ror': 'https://ror.org/01eq10738', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210103346']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xi Chen', 'raw_affiliation_strings': ['Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China', 'institution_ids': ['https://openalex.org/I58200834', 'https://openalex.org/I4210103346']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073294274', 'display_name': 'Li Sun', 'orcid': 'https://orcid.org/0000-0003-3069-6224'}, 'institutions': [{'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}, {'id': 'https://openalex.org/I4210103346', 'display_name': 'Nanfang Hospital', 'ror': 'https://ror.org/01eq10738', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210103346']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Li Sun', 'raw_affiliation_strings': ['Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China', 'institution_ids': ['https://openalex.org/I58200834', 'https://openalex.org/I4210103346']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029741432', 'display_name': 'Yulin Liao', 'orcid': 'https://orcid.org/0000-0001-5961-390X'}, 'institutions': [{'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}, {'id': 'https://openalex.org/I4210103346', 'display_name': 'Nanfang Hospital', 'ror': 'https://ror.org/01eq10738', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210103346']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yulin Liao', 'raw_affiliation_strings': ['Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China', 'institution_ids': ['https://openalex.org/I58200834', 'https://openalex.org/I4210103346']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007648897', 'display_name': 'Na Huang', 'orcid': 'https://orcid.org/0000-0001-5799-1894'}, 'institutions': [{'id': 'https://openalex.org/I4210103346', 'display_name': 'Nanfang Hospital', 'ror': 'https://ror.org/01eq10738', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210103346']}, {'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Na Huang', 'raw_affiliation_strings': ['Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China', 'institution_ids': ['https://openalex.org/I4210103346', 'https://openalex.org/I58200834']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5032770876', 'display_name': 'Wangjun Liao', 'orcid': 'https://orcid.org/0000-0002-1364-8442'}, 'institutions': [{'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}, {'id': 'https://openalex.org/I4210103346', 'display_name': 'Nanfang Hospital', 'ror': 'https://ror.org/01eq10738', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210103346']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wangjun Liao', 'raw_affiliation_strings': ['Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China', 'institution_ids': ['https://openalex.org/I58200834', 'https://openalex.org/I4210103346']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 5.435, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 67, 'citation_normalized_percentile': {'value': 0.999985, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '6', 'issue': '13', 'first_page': '11492', 'last_page': '11506'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10422', 'display_name': 'Angiogenesis and VEGF in Cancer', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10422', 'display_name': 'Angiogenesis and VEGF in Cancer', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10515', 'display_name': 'Cancer-related molecular mechanisms research', 'score': 0.9924, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10336', 'display_name': 'Cancer Cells and Metastasis', 'score': 0.9833, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/vasculogenic-mimicry', 'display_name': 'Vasculogenic mimicry', 'score': 0.976861}], 'concepts': [{'id': 'https://openalex.org/C2779944901', 'wikidata': 'https://www.wikidata.org/wiki/Q25324157', 'display_name': 'Vasculogenic mimicry', 'level': 4, 'score': 0.976861}, {'id': 'https://openalex.org/C76419328', 'wikidata': 'https://www.wikidata.org/wiki/Q74419', 'display_name': 'Epithelial–mesenchymal transition', 'level': 4, 'score': 0.69228125}, {'id': 'https://openalex.org/C2779013556', 'wikidata': 'https://www.wikidata.org/wiki/Q181876', 'display_name': 'Metastasis', 'level': 3, 'score': 0.68313634}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.6755629}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.611081}, {'id': 'https://openalex.org/C526805850', 'wikidata': 'https://www.wikidata.org/wiki/Q188874', 'display_name': 'Colorectal cancer', 'level': 3, 'score': 0.5843358}, {'id': 'https://openalex.org/C204232928', 'wikidata': 'https://www.wikidata.org/wiki/Q899285', 'display_name': 'Immunohistochemistry', 'level': 2, 'score': 0.5483055}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.49327368}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4013402}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.39832142}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.33924848}], 'mesh': [{'descriptor_ui': 'D000230', 'descriptor_name': 'Adenocarcinoma', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009389', 'descriptor_name': 'Neovascularization, Pathologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D012097', 'descriptor_name': 'Repressor Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D051879', 'descriptor_name': 'Twist-Related Protein 1', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000230', 'descriptor_name': 'Adenocarcinoma', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D000230', 'descriptor_name': 'Adenocarcinoma', 'qualifier_ui': 'Q000556', 'qualifier_name': 'secondary', 'is_major_topic': False}, {'descriptor_ui': 'D000230', 'descriptor_name': 'Adenocarcinoma', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D000230', 'descriptor_name': 'Adenocarcinoma', 'qualifier_ui': 'Q000098', 'qualifier_name': 'blood supply', 'is_major_topic': False}, {'descriptor_ui': 'D000230', 'descriptor_name': 'Adenocarcinoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058750', 'descriptor_name': 'Epithelial-Mesenchymal Transition', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017228', 'descriptor_name': 'Hepatocyte Growth Factor', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D017228', 'descriptor_name': 'Hepatocyte Growth Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D064593', 'descriptor_name': 'Heterografts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053208', 'descriptor_name': 'Kaplan-Meier Estimate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016688', 'descriptor_name': 'Mice, Inbred NOD', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008819', 'descriptor_name': 'Mice, Nude', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016513', 'descriptor_name': 'Mice, SCID', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009367', 'descriptor_name': 'Neoplasm Staging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011401', 'descriptor_name': 'Promoter Regions, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D047428', 'descriptor_name': 'Protein Kinase Inhibitors', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D047428', 'descriptor_name': 'Protein Kinase Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019859', 'descriptor_name': 'Proto-Oncogene Proteins c-met', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D019859', 'descriptor_name': 'Proto-Oncogene Proteins c-met', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D019859', 'descriptor_name': 'Proto-Oncogene Proteins c-met', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D034622', 'descriptor_name': 'RNA Interference', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012097', 'descriptor_name': 'Repressor Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012097', 'descriptor_name': 'Repressor Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000098', 'qualifier_name': 'blood supply', 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015534', 'descriptor_name': 'Trans-Activators', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D014158', 'descriptor_name': 'Transcription, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051879', 'descriptor_name': 'Twist-Related Protein 1', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D051879', 'descriptor_name': 'Twist-Related Protein 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.3416', 'pdf_url': 'https://www.oncotarget.com/article/3416/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4484471', 'pdf_url': 'https://europepmc.org/articles/pmc4484471?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484471', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25895023', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.3416', 'pdf_url': 'https://www.oncotarget.com/article/3416/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.53, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 47, 'referenced_works': ['https://openalex.org/W1532283611', 'https://openalex.org/W1651215666', 'https://openalex.org/W1964081206', 'https://openalex.org/W1967600348', 'https://openalex.org/W1970719970', 'https://openalex.org/W1971519347', 'https://openalex.org/W1980646624', 'https://openalex.org/W1985804036', 'https://openalex.org/W1990184148', 'https://openalex.org/W2000292756', 'https://openalex.org/W2000297746', 'https://openalex.org/W2007084896', 'https://openalex.org/W2014691022', 'https://openalex.org/W2017322644', 'https://openalex.org/W2017360056', 'https://openalex.org/W2024811210', 'https://openalex.org/W2029409898', 'https://openalex.org/W2030177283', 'https://openalex.org/W2032223065', 'https://openalex.org/W2033424243', 'https://openalex.org/W2036008499', 'https://openalex.org/W2045813899', 'https://openalex.org/W2049460219', 'https://openalex.org/W2049929854', 'https://openalex.org/W2051131006', 'https://openalex.org/W2051940224', 'https://openalex.org/W2052275819', 'https://openalex.org/W2067907901', 'https://openalex.org/W2072671183', 'https://openalex.org/W2083798214', 'https://openalex.org/W2086977969', 'https://openalex.org/W2089333424', 'https://openalex.org/W2097089862', 'https://openalex.org/W2102834068', 'https://openalex.org/W2104754475', 'https://openalex.org/W2110960566', 'https://openalex.org/W2111237964', 'https://openalex.org/W2112703519', 'https://openalex.org/W2114014236', 'https://openalex.org/W2125857654', 'https://openalex.org/W2128059540', 'https://openalex.org/W2128318768', 'https://openalex.org/W2129901487', 'https://openalex.org/W2152998293', 'https://openalex.org/W2161708429', 'https://openalex.org/W2267211344', 'https://openalex.org/W4231943691'], 'related_works': ['https://openalex.org/W4296188913', 'https://openalex.org/W3041026090', 'https://openalex.org/W3022892502', 'https://openalex.org/W2885811648', 'https://openalex.org/W2353465412', 'https://openalex.org/W2295552376', 'https://openalex.org/W2269787425', 'https://openalex.org/W2176631918', 'https://openalex.org/W2002597275', 'https://openalex.org/W1970423756'], 'abstract_inverted_index': {'//': [0], 'Lin': [1, 6], 'Wang': [2], '1': [3, 7, 11, 15, 23, 27, 28], ',': [4, 8, 12, 16, 20, 24], 'Li': [5, 13], 'Xi': [9], 'Chen': [10], 'Sun': [14], 'Yulin': [17], 'Liao': [18, 26], '2': [19, 39], 'Na': [21, 56], 'Huang': [22], 'Wangjun': [25, 52], 'Department': [29, 40], 'of': [30, 41, 124, 169, 199, 203, 253, 274, 287, 305, 319], 'Oncology,': [31], 'Nanfang': [32, 43], 'Hospital,': [33, 44], 'Southern': [34, 45], 'Medical': [35, 46], 'University,': [36, 47], 'Guangzhou,': [37, 48], 'China': [38, 49], 'Cardiology,': [42], 'Correspondence': [50], 'to:': [51], 'Liao,': [53], 'e-mail:': [54, 58], '[email protected]': [55], 'Huang,': [57], '[email protected]': [59], 'Keywords:': [60], 'metastasis-associated': [61, 109], 'in': [62, 110, 144, 157, 173, 196, 223, 239, 260, 283, 291, 338], 'colon': [63, 111], 'cancer-1,': [64], 'TWIST1/2,': [65], 'vasculogenic': [66], 'mimicry,': [67], 'gastric': [68, 127], 'cancer': [69, 128], 'Received:': [70], 'December': [71], '22,': [72], '2014': [73], 'Accepted:': [74], 'February': [75], '19,': [76], '2015': [77, 81], 'Published:': [78], 'March': [79], '20,': [80], 'ABSTRACT': [82], 'Vasculogenic': [83], 'mimicry': [84], '(VM)': [85], 'is': [86, 92], 'a': [87, 121, 325], 'blood': [88], 'supply': [89], 'modality': [90], 'that': [91, 108, 189, 334, 348], 'strongly': [93], 'associated': [94, 119], 'with': [95, 120, 126, 160, 180, 209, 264], 'the': [96, 115, 140, 167, 190, 197, 284, 316, 342], 'epithelial-mesenchymal': [97], 'transition': [98], '(EMT),': [99], 'TWIST1': [100, 170, 306], 'activation': [101], 'and': [102, 117, 138, 153, 164, 171, 183, 205, 233, 248, 256, 279, 290, 300, 322, 350], 'tumor': [103], 'progression.': [104], 'We': [105, 187], 'previously': [106], 'reported': [107], 'cancer-1': [112], '(MACC1)': [113], 'induced': [114, 280], 'EMT': [116], 'was': [118, 193, 206, 220, 237, 258], 'poor': [122], 'prognosis': [123], 'patients': [125, 159, 200, 224, 240], '(GC),': [129], 'but': [130], 'it': [131, 236], 'remains': [132], 'unknown': [133], 'whether': [134], 'MACC1': [135, 151, 210, 232, 247, 275, 295, 335, 349], 'promotes': [136, 336], 'VM': [137, 154, 175, 191, 282, 337], 'regulates': [139], 'TWIST': [141], 'signaling': [142, 344], 'pathway': [143, 352], 'GC.': [145, 359], 'In': [146], 'this': [147, 351], 'study,': [148], 'we': [149], 'investigated': [150, 166], 'expression': [152, 252, 278], 'by': [155, 176, 340], 'immunohistochemistry': [156], '88': [158], 'stage': [161], 'IV': [162], 'GC,': [163], 'also': [165], 'role': [168], 'TWIST2': [172, 257, 308], 'MACC1-induced': [174], 'using': [177], 'nude': [178, 288], 'mice': [179, 289], 'GC': [181, 184, 204, 261, 285, 292, 339], 'xenografts': [182, 286], 'cell': [185, 293], 'lines.': [186, 294], 'found': [188], 'density': [192], 'significantly': [194], 'increased': [195, 276, 315], 'tumors': [198, 226, 242], 'who': [201], 'died': [202], 'positively': [207], 'correlated': [208], 'immunoreactivity': [211], '(': [212, 269], 'p': [213, 270], '<': [214, 271], '0.05).': [215, 272], 'The': [216], '3-year': [217], 'survival': [218], 'rate': [219], 'only': [221], '8.6%': [222], 'whose': [225, 241], 'showed': [227], 'double': [228], 'positive': [229], 'staining': [230], 'for': [231, 245, 358], 'VM,': [234, 302], 'whereas': [235], '41.7%': [238], 'were': [243], 'negative': [244], 'both': [246], 'VM.': [249, 310], 'Moreover,': [250], 'nuclear': [251, 317], 'MACC1,': [254, 320], 'TWIST1,': [255, 321], 'upregulated': [259], 'tissues': [262, 268], 'compared': [263], 'matched': [265], 'adjacent': [266], 'non-tumorous': [267], 'Overexpression': [273], 'TWIST1/2': [277, 297], 'typical': [281], 'enhanced': [296], 'promoter': [298], 'activity': [299], 'facilitated': [301], 'while': [303, 324], 'silencing': [304], 'or': [307], 'inhibited': [309], 'Hepatocyte': [311], 'growth': [312], 'factor': [313], '(HGF)': [314], 'translocation': [318], 'TWIST2,': [323], 'c-Met': [326], 'inhibitor': [327], 'reduced': [328], 'these': [329], 'effects.': [330], 'These': [331], 'findings': [332], 'indicate': [333], 'regulating': [341], 'HGF/c-Met-TWIST1/2': [343], 'pathway,': [345], 'which': [346], 'means': [347], 'are': [353], 'potential': [354], 'new': [355], 'therapeutic': [356], 'targets': [357]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1935073111', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 20}, {'year': 2016, 'cited_by_count': 16}, {'year': 2015, 'cited_by_count': 3}], 'updated_date': '2025-01-04T23:43:58.805835', 'created_date': '2016-06-24'}