Publication Information

{'id': 'https://openalex.org/W1914632472', 'doi': 'https://doi.org/10.1002/ijc.28774', 'title': 'Expression of Concern: miR‐145 sensitizes ovarian cancer cells to paclitaxel by targeting Sp1 and Cdk6', 'display_name': 'Expression of Concern: miR‐145 sensitizes ovarian cancer cells to paclitaxel by targeting Sp1 and Cdk6', 'publication_year': 2014, 'publication_date': '2014-02-08', 'ids': {'openalex': 'https://openalex.org/W1914632472', 'doi': 'https://doi.org/10.1002/ijc.28774', 'mag': '1914632472', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24510775'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/ijc.28774', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.28774', 'source': {'id': 'https://openalex.org/S5382288', 'display_name': 'International Journal of Cancer', 'issn_l': '0020-7136', 'issn': ['0020-7136', '1097-0215'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.28774', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5020649070', 'display_name': 'Xiaolan Zhu', 'orcid': 'https://orcid.org/0000-0002-0499-8045'}, 'institutions': [{'id': 'https://openalex.org/I115592961', 'display_name': 'Jiangsu University', 'ror': 'https://ror.org/03jc41j30', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I115592961']}, {'id': 'https://openalex.org/I4210119046', 'display_name': 'Zero to Three', 'ror': 'https://ror.org/01qvk6016', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210119046']}], 'countries': ['CN', 'US'], 'is_corresponding': False, 'raw_author_name': 'Xiaolan Zhu', 'raw_affiliation_strings': ['Jiangsu University, school of medical science and laborratory medicine, Zhenjiang, Jiangsu, China', 'The Fourth Affiliated Hospital of Jiangsu University, Department of gynecology, Zhenjiang, Jiangsu, China', 'X.Z. and Y.L. contributed equally to this work'], 'affiliations': [{'raw_affiliation_string': 'The Fourth Affiliated Hospital of Jiangsu University, Department of gynecology, Zhenjiang, Jiangsu, China', 'institution_ids': ['https://openalex.org/I115592961']}, {'raw_affiliation_string': 'Jiangsu University, school of medical science and laborratory medicine, Zhenjiang, Jiangsu, China', 'institution_ids': ['https://openalex.org/I115592961']}, {'raw_affiliation_string': 'X.Z. and Y.L. contributed equally to this work', 'institution_ids': ['https://openalex.org/I4210119046']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100627251', 'display_name': 'Yuefeng Li', 'orcid': 'https://orcid.org/0000-0001-6807-3730'}, 'institutions': [{'id': 'https://openalex.org/I115592961', 'display_name': 'Jiangsu University', 'ror': 'https://ror.org/03jc41j30', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I115592961']}, {'id': 'https://openalex.org/I4210119046', 'display_name': 'Zero to Three', 'ror': 'https://ror.org/01qvk6016', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210119046']}, {'id': 'https://openalex.org/I4210111628', 'display_name': 'Affiliated Hospital of Jiangsu University', 'ror': 'https://ror.org/028pgd321', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210111628']}], 'countries': ['CN', 'US'], 'is_corresponding': False, 'raw_author_name': 'Yuefeng Li', 'raw_affiliation_strings': ['Jiangsu University, school of medical science and laborratory medicine, Zhenjiang, Jiangsu, China', 'The Affiliated Hospital of Jiangsu University, Department of radiology, Zhenjiang, Jiangsu, China', 'X.Z. and Y.L. contributed equally to this work'], 'affiliations': [{'raw_affiliation_string': 'The Affiliated Hospital of Jiangsu University, Department of radiology, Zhenjiang, Jiangsu, China', 'institution_ids': ['https://openalex.org/I115592961', 'https://openalex.org/I4210111628']}, {'raw_affiliation_string': 'Jiangsu University, school of medical science and laborratory medicine, Zhenjiang, Jiangsu, China', 'institution_ids': ['https://openalex.org/I115592961']}, {'raw_affiliation_string': 'X.Z. and Y.L. contributed equally to this work', 'institution_ids': ['https://openalex.org/I4210119046']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102958282', 'display_name': 'Chanjuan Xie', 'orcid': 'https://orcid.org/0000-0003-1475-1983'}, 'institutions': [{'id': 'https://openalex.org/I115592961', 'display_name': 'Jiangsu University', 'ror': 'https://ror.org/03jc41j30', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I115592961']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Chanjuan Xie', 'raw_affiliation_strings': ['Jiangsu University, school of medical science and laborratory medicine, Zhenjiang, Jiangsu, China'], 'affiliations': [{'raw_affiliation_string': 'Jiangsu University, school of medical science and laborratory medicine, Zhenjiang, Jiangsu, China', 'institution_ids': ['https://openalex.org/I115592961']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100688772', 'display_name': 'Xinming Yin', 'orcid': 'https://orcid.org/0000-0002-4203-1652'}, 'institutions': [{'id': 'https://openalex.org/I115592961', 'display_name': 'Jiangsu University', 'ror': 'https://ror.org/03jc41j30', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I115592961']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xinming Yin', 'raw_affiliation_strings': ['The Fourth Affiliated Hospital of Jiangsu University, Department of gynecology, Zhenjiang, Jiangsu, China'], 'affiliations': [{'raw_affiliation_string': 'The Fourth Affiliated Hospital of Jiangsu University, Department of gynecology, Zhenjiang, Jiangsu, China', 'institution_ids': ['https://openalex.org/I115592961']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5115595375', 'display_name': 'Yueqin Liu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I115592961', 'display_name': 'Jiangsu University', 'ror': 'https://ror.org/03jc41j30', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I115592961']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yueqin Liu', 'raw_affiliation_strings': ['The Fourth Affiliated Hospital of Jiangsu University, Department of gynecology, Zhenjiang, Jiangsu, China'], 'affiliations': [{'raw_affiliation_string': 'The Fourth Affiliated Hospital of Jiangsu University, Department of gynecology, Zhenjiang, Jiangsu, China', 'institution_ids': ['https://openalex.org/I115592961']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113705365', 'display_name': 'Yuan Cao', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I115592961', 'display_name': 'Jiangsu University', 'ror': 'https://ror.org/03jc41j30', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I115592961']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yuan Cao', 'raw_affiliation_strings': ['Jiangsu University, school of medical science and laborratory medicine, Zhenjiang, Jiangsu, China'], 'affiliations': [{'raw_affiliation_string': 'Jiangsu University, school of medical science and laborratory medicine, Zhenjiang, Jiangsu, China', 'institution_ids': ['https://openalex.org/I115592961']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058336972', 'display_name': 'Yue Fang', 'orcid': 'https://orcid.org/0000-0002-0557-2118'}, 'institutions': [{'id': 'https://openalex.org/I115592961', 'display_name': 'Jiangsu University', 'ror': 'https://ror.org/03jc41j30', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I115592961']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yue Fang', 'raw_affiliation_strings': ['Jiangsu University, school of medical science and laborratory medicine, Zhenjiang, Jiangsu, China'], 'affiliations': [{'raw_affiliation_string': 'Jiangsu University, school of medical science and laborratory medicine, Zhenjiang, Jiangsu, China', 'institution_ids': ['https://openalex.org/I115592961']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100735830', 'display_name': 'Xin Lin', 'orcid': 'https://orcid.org/0000-0001-6513-9095'}, 'institutions': [{'id': 'https://openalex.org/I115592961', 'display_name': 'Jiangsu University', 'ror': 'https://ror.org/03jc41j30', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I115592961']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xin Lin', 'raw_affiliation_strings': ['The Fourth Affiliated Hospital of Jiangsu University, Department of gynecology, Zhenjiang, Jiangsu, China'], 'affiliations': [{'raw_affiliation_string': 'The Fourth Affiliated Hospital of Jiangsu University, Department of gynecology, Zhenjiang, Jiangsu, China', 'institution_ids': ['https://openalex.org/I115592961']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100656915', 'display_name': 'Yao Xu', 'orcid': 'https://orcid.org/0000-0002-6515-7303'}, 'institutions': [{'id': 'https://openalex.org/I115592961', 'display_name': 'Jiangsu University', 'ror': 'https://ror.org/03jc41j30', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I115592961']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yao Xu', 'raw_affiliation_strings': ['The Fourth Affiliated Hospital of Jiangsu University, Department of gynecology, Zhenjiang, Jiangsu, China'], 'affiliations': [{'raw_affiliation_string': 'The Fourth Affiliated Hospital of Jiangsu University, Department of gynecology, Zhenjiang, Jiangsu, China', 'institution_ids': ['https://openalex.org/I115592961']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074775577', 'display_name': 'Wenlin Xu', 'orcid': 'https://orcid.org/0000-0001-7518-7912'}, 'institutions': [{'id': 'https://openalex.org/I115592961', 'display_name': 'Jiangsu University', 'ror': 'https://ror.org/03jc41j30', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I115592961']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Wenlin Xu', 'raw_affiliation_strings': ['Jiangsu University, school of medical science and laborratory medicine, Zhenjiang, Jiangsu, China', 'The Fourth Affiliated Hospital of Jiangsu University, Department of gynecology, Zhenjiang, Jiangsu, China'], 'affiliations': [{'raw_affiliation_string': 'The Fourth Affiliated Hospital of Jiangsu University, Department of gynecology, Zhenjiang, Jiangsu, China', 'institution_ids': ['https://openalex.org/I115592961']}, {'raw_affiliation_string': 'Jiangsu University, school of medical science and laborratory medicine, Zhenjiang, Jiangsu, China', 'institution_ids': ['https://openalex.org/I115592961']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038836334', 'display_name': 'Huiling Shen', 'orcid': 'https://orcid.org/0000-0001-5590-7716'}, 'institutions': [{'id': 'https://openalex.org/I115592961', 'display_name': 'Jiangsu University', 'ror': 'https://ror.org/03jc41j30', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I115592961']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Huiling Shen', 'raw_affiliation_strings': ['The Affiliated People Hospital of Jiangsu University, Department of oncology, Zhenjiang, Jiangsu, China'], 'affiliations': [{'raw_affiliation_string': 'The Affiliated People Hospital of Jiangsu University, Department of oncology, Zhenjiang, Jiangsu, China', 'institution_ids': ['https://openalex.org/I115592961']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5076937292', 'display_name': 'Jian Wen', 'orcid': 'https://orcid.org/0000-0002-2297-4346'}, 'institutions': [{'id': 'https://openalex.org/I115592961', 'display_name': 'Jiangsu University', 'ror': 'https://ror.org/03jc41j30', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I115592961']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jian Wen', 'raw_affiliation_strings': ['The Fourth Affiliated Hospital of Jiangsu University, Department of gynecology, Zhenjiang, Jiangsu, China'], 'affiliations': [{'raw_affiliation_string': 'The Fourth Affiliated Hospital of Jiangsu University, Department of gynecology, Zhenjiang, Jiangsu, China', 'institution_ids': ['https://openalex.org/I115592961']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5074775577'], 'corresponding_institution_ids': ['https://openalex.org/I115592961'], 'apc_list': {'value': 4840, 'currency': 'USD', 'value_usd': 4840, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 4.7, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 109, 'citation_normalized_percentile': {'value': 0.999894, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '135', 'issue': '6', 'first_page': '1286', 'last_page': '1296'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA in disease regulation', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA in disease regulation', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11765', 'display_name': 'Circular RNAs in diseases', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13779', 'display_name': 'Cancer Mechanisms and Therapy', 'score': 0.9967, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cyclin-dependent-kinase-6', 'display_name': 'Cyclin-dependent kinase 6', 'score': 0.73308885}], 'concepts': [{'id': 'https://openalex.org/C2777292972', 'wikidata': 'https://www.wikidata.org/wiki/Q423762', 'display_name': 'Paclitaxel', 'level': 3, 'score': 0.85727084}, {'id': 'https://openalex.org/C199649820', 'wikidata': 'https://www.wikidata.org/wiki/Q14911762', 'display_name': 'Cyclin-dependent kinase 6', 'level': 5, 'score': 0.73308885}, {'id': 'https://openalex.org/C2780427987', 'wikidata': 'https://www.wikidata.org/wiki/Q172341', 'display_name': 'Ovarian cancer', 'level': 3, 'score': 0.6092132}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.58102566}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.48488912}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.48135334}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.47841153}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.4629309}, {'id': 'https://openalex.org/C145059251', 'wikidata': 'https://www.wikidata.org/wiki/Q310899', 'display_name': 'microRNA', 'level': 3, 'score': 0.442146}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.39207292}, {'id': 'https://openalex.org/C29537977', 'wikidata': 'https://www.wikidata.org/wiki/Q188941', 'display_name': 'Cell cycle', 'level': 3, 'score': 0.19220328}, {'id': 'https://openalex.org/C124320809', 'wikidata': 'https://www.wikidata.org/wiki/Q46292', 'display_name': 'Cyclin-dependent kinase', 'level': 4, 'score': 0.14487252}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.13848191}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.12938198}], 'mesh': [{'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D020168', 'descriptor_name': 'ATP Binding Cassette Transporter, Subfamily B, Member 1', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000972', 'descriptor_name': 'Antineoplastic Agents, Phytogenic', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': False}, {'descriptor_ui': 'D059447', 'descriptor_name': 'Cell Cycle Checkpoints', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051361', 'descriptor_name': 'Cyclin-Dependent Kinase 6', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D019008', 'descriptor_name': 'Drug Resistance, Neoplasm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D061986', 'descriptor_name': 'MCF-7 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008807', 'descriptor_name': 'Mice, Inbred BALB C', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010051', 'descriptor_name': 'Ovarian Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D017239', 'descriptor_name': 'Paclitaxel', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': False}, {'descriptor_ui': 'D034741', 'descriptor_name': 'RNA, Small Interfering', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D016160', 'descriptor_name': 'Retinoblastoma Protein', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D016329', 'descriptor_name': 'Sp1 Transcription Factor', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D023041', 'descriptor_name': 'Xenograft Model Antitumor Assays', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/ijc.28774', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.28774', 'source': {'id': 'https://openalex.org/S5382288', 'display_name': 'International Journal of Cancer', 'issn_l': '0020-7136', 'issn': ['0020-7136', '1097-0215'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24510775', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/ijc.28774', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.28774', 'source': {'id': 'https://openalex.org/S5382288', 'display_name': 'International Journal of Cancer', 'issn_l': '0020-7136', 'issn': ['0020-7136', '1097-0215'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.81, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [{'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81070423'}], 'datasets': [], 'versions': [], 'referenced_works_count': 43, 'referenced_works': ['https://openalex.org/W1546270188', 'https://openalex.org/W1965256565', 'https://openalex.org/W1970583256', 'https://openalex.org/W1985825541', 'https://openalex.org/W1988137199', 'https://openalex.org/W1989328481', 'https://openalex.org/W1997261348', 'https://openalex.org/W2000737962', 'https://openalex.org/W2005608256', 'https://openalex.org/W2009422749', 'https://openalex.org/W2022796941', 'https://openalex.org/W2031621381', 'https://openalex.org/W2035821927', 'https://openalex.org/W2042357886', 'https://openalex.org/W2058916559', 'https://openalex.org/W2059806955', 'https://openalex.org/W2064227724', 'https://openalex.org/W2077613098', 'https://openalex.org/W2086299158', 'https://openalex.org/W2090034342', 'https://openalex.org/W2091166689', 'https://openalex.org/W2098957807', 'https://openalex.org/W2099258232', 'https://openalex.org/W2099692224', 'https://openalex.org/W2101579321', 'https://openalex.org/W2111783800', 'https://openalex.org/W2115874527', 'https://openalex.org/W2120620274', 'https://openalex.org/W2123961393', 'https://openalex.org/W2125536613', 'https://openalex.org/W2138134990', 'https://openalex.org/W2141375939', 'https://openalex.org/W2144241792', 'https://openalex.org/W2146157095', 'https://openalex.org/W2151707292', 'https://openalex.org/W2155445572', 'https://openalex.org/W2156543203', 'https://openalex.org/W2162066487', 'https://openalex.org/W2162097274', 'https://openalex.org/W2163724251', 'https://openalex.org/W2169332120', 'https://openalex.org/W2169902067', 'https://openalex.org/W2170956481'], 'related_works': ['https://openalex.org/W4244054686', 'https://openalex.org/W3149674127', 'https://openalex.org/W3147219444', 'https://openalex.org/W2891057236', 'https://openalex.org/W2316397280', 'https://openalex.org/W2034199499', 'https://openalex.org/W2012996470', 'https://openalex.org/W1987294960', 'https://openalex.org/W1963667957', 'https://openalex.org/W1582696369'], 'abstract_inverted_index': {'Multidrug': [0], 'resistance': [1], '(MDR)': [2], 'remains': [3], 'a': [4, 45], 'major': [5], 'obstacle': [6], 'to': [7, 44, 78, 128, 145, 151], 'effective': [8], 'chemotherapy': [9], 'treatment': [10], 'in': [11, 47, 61, 80, 83, 104, 133, 142, 163], 'ovarian': [12, 18, 135, 164], 'cancer.': [13], 'In': [14], 'our': [15], 'study,': [16], 'paclitaxel‐resistant': [17], 'cancer': [19, 136, 165], 'patients': [20], 'and': [21, 28, 34, 40, 49, 56, 67, 82, 108, 117, 170], 'cell': [22, 69, 137], 'lines': [23], 'had': [24], 'decreased': [25], 'miR‐145': [26, 37, 131, 156], 'levels': [27, 31, 100], 'expressed': [29], 'high': [30, 99], 'of': [32, 54, 64, 101, 106, 121, 130, 155, 161], 'Sp1': [33, 50, 93, 118], 'Cdk6.': [35], 'Introducing': [36], 'into': [38, 96], 'SKOV3/PTX': [39], 'A2780/PTX': [41], 'cells': [42, 75, 97], 'led': [43, 127], 'reduction': [46], 'Cdk6': [48, 95, 116, 169], 'along': [51], 'with': [52, 125], 'downregulation': [53], 'P‐gp': [55, 107], 'pRb.': [57], 'These': [58, 86], 'changes': [59], 'resulted': [60, 141], 'increased': [62, 143], 'accumulation': [63], 'antineoplastic': [65], 'drugs': [66], 'G1': [68], 'cycle': [70], 'arrest,': [71], 'which': [72, 139], 'rendered': [73], 'the': [74, 153], 'more': [76], 'sensitive': [77], 'paclitaxel': [79], 'vitro': [81], 'vivo': [84], '.': [85], 'effects': [87], 'could': [88], 'be': [89], 'reversed': [90], 'by': [91, 166], 'reintroducing': [92], 'or': [94], 'expressing': [98], 'miR‐145,': [102], 'resulting': [103], 'restoration': [105], 'pRb': [109], 'levels.': [110], 'Furthermore,': [111], 'we': [112], 'confirmed': [113], 'that': [114], 'both': [115, 168], 'are': [119], 'targets': [120], 'miR‐145.': [122], 'Intriguingly,': [123], 'demethylation': [124], '5‐aza‐dC': [126], 'reactivation': [129], 'expression': [132], 'drug‐resistant': [134], 'lines,': [138], 'also': [140], 'sensitivity': [144], 'paclitaxel.': [146], 'Collectively,': [147], 'these': [148], 'findings': [149], 'begin': [150], 'elucidate': [152], 'role': [154], 'as': [157], 'an': [158], 'important': [159], 'regulator': [160], 'chemoresistance': [162], 'controlling': [167], 'Sp1.': [171]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1914632472', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 6}, {'year': 2021, 'cited_by_count': 16}, {'year': 2020, 'cited_by_count': 11}, {'year': 2019, 'cited_by_count': 21}, {'year': 2018, 'cited_by_count': 8}, {'year': 2017, 'cited_by_count': 14}, {'year': 2016, 'cited_by_count': 9}, {'year': 2015, 'cited_by_count': 14}, {'year': 2014, 'cited_by_count': 4}], 'updated_date': '2024-12-24T16:14:42.272436', 'created_date': '2016-06-24'}