Publication Information

{'id': 'https://openalex.org/W1909773795', 'doi': None, 'title': 'Effect of smoking history on [3H]nicotine binding in human postmortem brain.', 'display_name': 'Effect of smoking history on [3H]nicotine binding in human postmortem brain.', 'publication_year': 1997, 'publication_date': '1997-07-01', 'ids': {'openalex': 'https://openalex.org/W1909773795', 'mag': '1909773795', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9223534'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9223534', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5060191609', 'display_name': 'Charles R. Breese', 'orcid': 'https://orcid.org/0000-0003-1622-3551'}, 'institutions': [{'id': 'https://openalex.org/I4210087413', 'display_name': 'University of Colorado Health', 'ror': 'https://ror.org/0107w4315', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087413']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'C R Breese', 'raw_affiliation_strings': ['Department of Psychiatry, University of Colorado Health Sciences Center, Denver 80262, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Psychiatry, University of Colorado Health Sciences Center, Denver 80262, USA.', 'institution_ids': ['https://openalex.org/I4210087413']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080448364', 'display_name': 'Michael J. Marks', 'orcid': 'https://orcid.org/0000-0003-1383-8948'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'M J Marks', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111895679', 'display_name': 'Judith Logel', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'J Logel', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108304010', 'display_name': 'C.E. Adams', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'C E Adams', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113515255', 'display_name': 'B Sullivan', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'B Sullivan', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110435829', 'display_name': 'Allan C. Collins', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'A C Collins', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5079305426', 'display_name': 'Sherry Leonard', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'S Leonard', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 4.657, 'has_fulltext': False, 'cited_by_count': 382, 'citation_normalized_percentile': {'value': 0.96391, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '282', 'issue': '1', 'first_page': '7', 'last_page': '13'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11818', 'display_name': 'Nicotinic Acetylcholine Receptors Study', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11818', 'display_name': 'Nicotinic Acetylcholine Receptors Study', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11178', 'display_name': 'Receptor Mechanisms and Signaling', 'score': 0.9933, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10056', 'display_name': 'Neurotransmitter Receptor Influence on Behavior', 'score': 0.9839, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/human-brain', 'display_name': 'Human brain', 'score': 0.4821072}], 'concepts': [{'id': 'https://openalex.org/C2779547902', 'wikidata': 'https://www.wikidata.org/wiki/Q28086552', 'display_name': 'Nicotine', 'level': 2, 'score': 0.9225168}, {'id': 'https://openalex.org/C188987157', 'wikidata': 'https://www.wikidata.org/wiki/Q7030581', 'display_name': 'Nicotinic agonist', 'level': 3, 'score': 0.68753123}, {'id': 'https://openalex.org/C2781161787', 'wikidata': 'https://www.wikidata.org/wiki/Q48360', 'display_name': 'Hippocampus', 'level': 2, 'score': 0.60996056}, {'id': 'https://openalex.org/C2779246727', 'wikidata': 'https://www.wikidata.org/wiki/Q184215', 'display_name': 'Thalamus', 'level': 2, 'score': 0.54785246}, {'id': 'https://openalex.org/C2777670902', 'wikidata': 'https://www.wikidata.org/wiki/Q492038', 'display_name': 'Human brain', 'level': 2, 'score': 0.4821072}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4700987}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.45969334}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.45085543}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.4427977}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.43125972}, {'id': 'https://openalex.org/C2777843972', 'wikidata': 'https://www.wikidata.org/wiki/Q2462253', 'display_name': 'Smoking cessation', 'level': 2, 'score': 0.41539785}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.32755172}, {'id': 'https://openalex.org/C42407357', 'wikidata': 'https://www.wikidata.org/wiki/Q521', 'display_name': 'Physiology', 'level': 1, 'score': 0.3261857}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.2775441}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.25494438}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.1356704}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.11128166}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009538', 'descriptor_name': 'Nicotine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D012907', 'descriptor_name': 'Smoking', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009538', 'descriptor_name': 'Nicotine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011978', 'descriptor_name': 'Receptors, Nicotinic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011978', 'descriptor_name': 'Receptors, Nicotinic', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D012907', 'descriptor_name': 'Smoking', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014316', 'descriptor_name': 'Tritium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9223534', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.89, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 36, 'referenced_works': ['https://openalex.org/W1552994668', 'https://openalex.org/W1849283303', 'https://openalex.org/W1869080905', 'https://openalex.org/W1938084083', 'https://openalex.org/W1965948815', 'https://openalex.org/W1985313555', 'https://openalex.org/W1989689679', 'https://openalex.org/W1998808332', 'https://openalex.org/W2002964463', 'https://openalex.org/W2008378478', 'https://openalex.org/W2010895202', 'https://openalex.org/W2024566705', 'https://openalex.org/W2025419025', 'https://openalex.org/W2033254523', 'https://openalex.org/W2038995429', 'https://openalex.org/W2043194007', 'https://openalex.org/W2048346500', 'https://openalex.org/W2069003947', 'https://openalex.org/W2072052138', 'https://openalex.org/W2080031511', 'https://openalex.org/W2085063402', 'https://openalex.org/W2090264816', 'https://openalex.org/W2091374932', 'https://openalex.org/W2093932843', 'https://openalex.org/W2102510891', 'https://openalex.org/W2114226110', 'https://openalex.org/W2116249462', 'https://openalex.org/W2118928503', 'https://openalex.org/W2155400043', 'https://openalex.org/W2159684233', 'https://openalex.org/W2163138024', 'https://openalex.org/W2335199875', 'https://openalex.org/W2340141139', 'https://openalex.org/W2344330649', 'https://openalex.org/W2406721842', 'https://openalex.org/W2764550917'], 'related_works': ['https://openalex.org/W4286214931', 'https://openalex.org/W2347118468', 'https://openalex.org/W2157648117', 'https://openalex.org/W2100369159', 'https://openalex.org/W2097972210', 'https://openalex.org/W2081000346', 'https://openalex.org/W2079605066', 'https://openalex.org/W2062519297', 'https://openalex.org/W1986867990', 'https://openalex.org/W1909773795'], 'abstract_inverted_index': {'Chronic': [0], 'nicotine': [1, 47, 153, 204, 221], 'administration': [2], 'in': [3, 10, 18, 22, 49, 64, 93, 96, 116, 124, 157, 170, 177, 190, 211, 215, 225], 'animal': [4], 'models': [5], 'evokes': [6], 'a': [7, 114, 131, 167], 'dose-dependent': [8, 168], 'increase': [9, 90, 169], 'brain': [11, 67, 171, 179, 218], 'nicotinic': [12, 19, 172, 212], 'receptor': [13, 20, 118, 125, 173, 213], 'numbers.': [14], 'Genetically': [15], 'determined': [16], 'variability': [17], 'number': [21, 119, 151], 'different': [23], 'mouse': [24], 'strains': [25], 'has': [26], 'also': [27, 130], 'been': [28], 'reported,': [29], 'which': [30, 194], 'is': [31], 'thought': [32], 'to': [33, 36], 'affect': [34], 'sensitivity': [35], 'nicotine,': [37], 'as': [38, 40, 139], 'well': [39], 'the': [41, 50, 108, 135, 142, 150, 159, 191, 216], 'development': [42], 'of': [43, 52, 72, 101, 137, 152, 203], 'tolerance.': [44], 'Humans': [45], 'self-administer': [46], 'principally': [48], 'form': [51], 'cigarettes': [53], 'and': [54, 70, 82, 99, 149, 161, 223], 'other': [55], 'tobacco': [56], 'products.': [57], 'The': [58], 'present': [59], 'study': [60], 'compared': [61], '[3H]nicotine': [62, 94], 'binding': [63, 95, 154], 'human': [65, 217], 'postmortem': [66], 'from': [68, 113], 'thalamus': [69, 100], 'hippocampus': [71, 98, 160], 'nonsmoking': [73], 'subjects,': [74], 'subjects': [75, 83, 102], 'who': [76, 84], 'had': [77, 85], 'variable': [78], 'life-long': [79, 104], 'smoking': [80, 105, 182], 'histories': [81], 'quit': [86], 'smoking.': [87], 'A': [88], 'significant': [89], 'was': [91, 129], 'seen': [92], 'both': [97, 158], 'with': [103, 121], 'histories.': [106], 'In': [107], 'hippocampus,': [109], 'this': [110], 'change': [111, 115, 123], 'resulted': [112], 'total': [117], '(Bmax),': [120], 'no': [122], 'affinity': [126], '(Kd).': [127], 'There': [128], 'positive': [132], 'correlation': [133], 'between': [134], 'degree': [136], 'smoking,': [138], 'measured': [140], 'by': [141], 'average': [143], 'reported': [144], 'packs': [145], 'smoked': [146], 'per': [147], 'day,': [148], 'sites': [155], 'found': [156, 189], 'thalamus,': [162], 'showing': [163], 'that': [164, 196, 209], 'humans': [165], 'exhibit': [166], 'binding.': [174], 'Receptor': [175], 'levels': [176, 214], 'these': [178], 'regions': [180], 'after': [181, 201], 'cessation': [183, 202], 'were': [184], 'at': [185], 'or': [186], 'below': [187], 'those': [188], 'control': [192], 'population,': [193], 'indicated': [195], 'smoking-induced': [197], 'changes': [198], 'are': [199], 'reversible': [200], 'treatment.': [205], 'These': [206], 'results': [207], 'suggest': [208], 'increases': [210], 'may': [219], 'underlie': [220], 'tolerance': [222], 'addiction': [224], 'smokers.': [226]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1909773795', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 28}, {'year': 2019, 'cited_by_count': 8}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 17}, {'year': 2015, 'cited_by_count': 19}, {'year': 2014, 'cited_by_count': 14}, {'year': 2013, 'cited_by_count': 19}, {'year': 2012, 'cited_by_count': 17}], 'updated_date': '2024-12-14T03:49:08.958724', 'created_date': '2016-06-24'}