Title: Antimicrobial efficacy of non-thermal plasma in comparison to chlorhexidine against dental biofilms on titanium discs in vitro - proof of principle experiment
Abstract: Journal of Clinical PeriodontologyVolume 38, Issue 10 p. 956-965 Antimicrobial efficacy of non-thermal plasma in comparison to chlorhexidine against dental biofilms on titanium discs in vitro – proof of principle experiment Ina Koban, Ina Koban Department of Restorative Dentistry, Periodontology and Endodontology, Unit of Periodontology, Ernst-Moritz-Arndt University Greifswald, GermanySearch for more papers by this authorBirte Holtfreter, Birte Holtfreter Department of Restorative Dentistry, Periodontology and Endodontology, Unit of Periodontology, Ernst-Moritz-Arndt University Greifswald, GermanySearch for more papers by this authorNils-Olaf Hübner, Nils-Olaf Hübner Institute for Hygiene and Environmental Medicine, Ernst-Moritz-Arndt University Greifswald, GermanySearch for more papers by this authorRutger Matthes, Rutger Matthes Institute for Hygiene and Environmental Medicine, Ernst-Moritz-Arndt University Greifswald, GermanySearch for more papers by this authorRabea Sietmann, Rabea Sietmann Institute of Microbiology, Ernst-Moritz-Arndt University Greifswald, GermanySearch for more papers by this authorEckhard Kindel, Eckhard Kindel Leibniz Institute for Plasma Science and Technology, Greifswald, GermanySearch for more papers by this authorKlaus-Dieter Weltmann, Klaus-Dieter Weltmann Leibniz Institute for Plasma Science and Technology, Greifswald, GermanySearch for more papers by this authorAlexander Welk, Alexander Welk Department of Restorative Dentistry, Periodontology and Endodontology, Unit of Periodontology, Ernst-Moritz-Arndt University Greifswald, GermanySearch for more papers by this authorAxel Kramer, Axel Kramer Institute for Hygiene and Environmental Medicine, Ernst-Moritz-Arndt University Greifswald, GermanySearch for more papers by this authorThomas Kocher, Thomas Kocher Department of Restorative Dentistry, Periodontology and Endodontology, Unit of Periodontology, Ernst-Moritz-Arndt University Greifswald, GermanySearch for more papers by this author Ina Koban, Ina Koban Department of Restorative Dentistry, Periodontology and Endodontology, Unit of Periodontology, Ernst-Moritz-Arndt University Greifswald, GermanySearch for more papers by this authorBirte Holtfreter, Birte Holtfreter Department of Restorative Dentistry, Periodontology and Endodontology, Unit of Periodontology, Ernst-Moritz-Arndt University Greifswald, GermanySearch for more papers by this authorNils-Olaf Hübner, Nils-Olaf Hübner Institute for Hygiene and Environmental Medicine, Ernst-Moritz-Arndt University Greifswald, GermanySearch for more papers by this authorRutger Matthes, Rutger Matthes Institute for Hygiene and Environmental Medicine, Ernst-Moritz-Arndt University Greifswald, GermanySearch for more papers by this authorRabea Sietmann, Rabea Sietmann Institute of Microbiology, Ernst-Moritz-Arndt University Greifswald, GermanySearch for more papers by this authorEckhard Kindel, Eckhard Kindel Leibniz Institute for Plasma Science and Technology, Greifswald, GermanySearch for more papers by this authorKlaus-Dieter Weltmann, Klaus-Dieter Weltmann Leibniz Institute for Plasma Science and Technology, Greifswald, GermanySearch for more papers by this authorAlexander Welk, Alexander Welk Department of Restorative Dentistry, Periodontology and Endodontology, Unit of Periodontology, Ernst-Moritz-Arndt University Greifswald, GermanySearch for more papers by this authorAxel Kramer, Axel Kramer Institute for Hygiene and Environmental Medicine, Ernst-Moritz-Arndt University Greifswald, GermanySearch for more papers by this authorThomas Kocher, Thomas Kocher Department of Restorative Dentistry, Periodontology and Endodontology, Unit of Periodontology, Ernst-Moritz-Arndt University Greifswald, GermanySearch for more papers by this author First published: 15 July 2011 https://doi.org/10.1111/j.1600-051X.2011.01740.xCitations: 104 Address:Ina KobanDepartment of Restorative Dentistry, Periodontology, and EndodontologyUnit of PeriodontologyErnst-Moritz-Arndt University GreifswaldWalther-Rathenau-Straße 49a17487 GreifswaldGermanyEmail: [email protected] Conflicts of interest and source of funding statement The authors declare that they have no conflict of interests.This work was supported by a grant (“Campus PlasmaMed”, particularly “PlasmaDent”) funded by the German Ministry of Education and Research (BMBF, grant no, 13N9779). B. H. was financed by an unlimited educational grant by Gaba, Switzerland.All titanium discs were kindly provided by Straumann. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Koban I, Holtfreter B, Hübner N-O, Matthes R, Sietmann R, Kindel E, Weltmann K-D, Welk A, Kramer A, Kocher T. Antimicrobial efficacy of non-thermal plasma in comparison to chlorhexidine against dental biofilms on titanium discs in vitro – proof of principle experiment. J Clin Periodontol 2011; 38: 956–965. doi: 10.1111/j.1600-051X.2011.01740.x. Abstract Aim: Dental biofilms play a major role in the pathogenesis of peri-implant mucositis. Biofilm reduction is a pre-requisite for a successful therapy of peri-implant mucosal lesions. In this study, we evaluated the effect of three different plasma devices on the reduction of Streptococcus mutans (S. mutans) and multispecies human saliva biofilms. Material and Methods: We assessed the efficacy of three different non-thermal atmospheric pressure plasma devices against biofilms of S. mutans and saliva multispecies grown on titanium discs in vitro in comparison with a chlorhexidine digluconate (CHX) rinse. Efficacy of plasma treatment was determined by the number of colony forming units (CFU) and by scanning electron microscopy. The results were reported as reduction of CFU (CFUuntreated−CFUtreated). Results: The application of plasma was much more effective than CHX against biofilms. The maximum reduction of CHX was 3.36 for S. mutans biofilm and 1.50 for saliva biofilm, whereas the colony forming units (CFU) reduction of the volume dielectric barrier discharge argon plasma was 5.38 for S. mutans biofilm and 5.67 for saliva biofilm. Conclusions: Treatment of single- and multispecies dental biofilms on titanium discs with non-thermal atmospheric pressure plasma was more efficient than CHX application in vitro. Thus, the development of plasma devices for the treatment of peri-implant mucositis may be fruitful. Citing Literature Volume38, Issue10October 2011Pages 956-965 RelatedInformation
Publication Year: 2011
Publication Date: 2011-07-15
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 146
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