Publication Information

{'id': 'https://openalex.org/W1905499183', 'doi': 'https://doi.org/10.18632/oncotarget.1747', 'title': 'Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: <i>in vitro</i> and <i>in vivo</i> anti-tumor activity', 'display_name': 'Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: <i>in vitro</i> and <i>in vivo</i> anti-tumor activity', 'publication_year': 2014, 'publication_date': '2014-03-14', 'ids': {'openalex': 'https://openalex.org/W1905499183', 'doi': 'https://doi.org/10.18632/oncotarget.1747', 'mag': '1905499183', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24839982', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4102790'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.1747', 'pdf_url': 'https://www.oncotarget.com/article/1747/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.oncotarget.com/article/1747/pdf/', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5024989705', 'display_name': 'Lavinia Raimondi', 'orcid': 'https://orcid.org/0000-0001-9394-2002'}, 'institutions': [{'id': 'https://openalex.org/I36443711', 'display_name': 'Magna Graecia University', 'ror': 'https://ror.org/0530bdk91', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I36443711']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Lavinia Raimondi', 'raw_affiliation_strings': ['Department of Experimental and Clinical Medicine; Magna Graecia University and Medical Oncology Unit; T. Campanella Cancer Center; Salvatore Venuta University Campus; Catanzaro, Italy.'], 'affiliations': [{'raw_affiliation_string': 'Department of Experimental and Clinical Medicine; Magna Graecia University and Medical Oncology Unit; T. Campanella Cancer Center; Salvatore Venuta University Campus; Catanzaro, Italy.', 'institution_ids': ['https://openalex.org/I36443711']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077777265', 'display_name': 'Nicola Amodio', 'orcid': 'https://orcid.org/0000-0001-6061-626X'}, 'institutions': [{'id': 'https://openalex.org/I36443711', 'display_name': 'Magna Graecia University', 'ror': 'https://ror.org/0530bdk91', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I36443711']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Nicola Amodio', 'raw_affiliation_strings': ['Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy', 'institution_ids': ['https://openalex.org/I36443711']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031409644', 'display_name': 'Maria Teresa Di Martino', 'orcid': 'https://orcid.org/0000-0002-8205-2706'}, 'institutions': [{'id': 'https://openalex.org/I36443711', 'display_name': 'Magna Graecia University', 'ror': 'https://ror.org/0530bdk91', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I36443711']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Maria Teresa Di Martino', 'raw_affiliation_strings': ['Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy', 'institution_ids': ['https://openalex.org/I36443711']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037164327', 'display_name': 'Emanuela Altomare', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I36443711', 'display_name': 'Magna Graecia University', 'ror': 'https://ror.org/0530bdk91', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I36443711']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Emanuela Altomare', 'raw_affiliation_strings': ['Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy', 'institution_ids': ['https://openalex.org/I36443711']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027116725', 'display_name': 'Marzia Leotta', 'orcid': 'https://orcid.org/0000-0001-8466-6384'}, 'institutions': [{'id': 'https://openalex.org/I36443711', 'display_name': 'Magna Graecia University', 'ror': 'https://ror.org/0530bdk91', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I36443711']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Marzia Leotta', 'raw_affiliation_strings': ['Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy', 'institution_ids': ['https://openalex.org/I36443711']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087294312', 'display_name': 'Daniele Caracciolo', 'orcid': 'https://orcid.org/0000-0001-7870-7565'}, 'institutions': [{'id': 'https://openalex.org/I36443711', 'display_name': 'Magna Graecia University', 'ror': 'https://ror.org/0530bdk91', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I36443711']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Daniele Caracciolo', 'raw_affiliation_strings': ['Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy', 'institution_ids': ['https://openalex.org/I36443711']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084463088', 'display_name': 'Annamaria Gullà', 'orcid': 'https://orcid.org/0000-0003-4569-0095'}, 'institutions': [{'id': 'https://openalex.org/I36443711', 'display_name': 'Magna Graecia University', 'ror': 'https://ror.org/0530bdk91', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I36443711']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Annamaria Gullà', 'raw_affiliation_strings': ['Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy', 'institution_ids': ['https://openalex.org/I36443711']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042629318', 'display_name': 'Antonino Neri', 'orcid': 'https://orcid.org/0000-0001-9047-5912'}, 'institutions': [{'id': 'https://openalex.org/I189158943', 'display_name': 'University of Milan', 'ror': 'https://ror.org/00wjc7c48', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I189158943']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Antonino Neri', 'raw_affiliation_strings': ['Department of Medical Sciences University of Milan, Hematology1, IRCCS Policlinico Foundation, Milan, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Medical Sciences University of Milan, Hematology1, IRCCS Policlinico Foundation, Milan, Italy', 'institution_ids': ['https://openalex.org/I189158943']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063568102', 'display_name': 'Simona Taverna', 'orcid': 'https://orcid.org/0000-0002-2192-8938'}, 'institutions': [{'id': 'https://openalex.org/I900890020', 'display_name': 'University of Palermo', 'ror': 'https://ror.org/044k9ta02', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I900890020']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Simona Taverna', 'raw_affiliation_strings': ['Department of Pathology and Forensic and Medical Biotechnology, Section of Biology and Genetics, University of Palermo, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology and Forensic and Medical Biotechnology, Section of Biology and Genetics, University of Palermo, Italy', 'institution_ids': ['https://openalex.org/I900890020']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062743881', 'display_name': 'Patrizia D’Aquila', 'orcid': 'https://orcid.org/0000-0001-5740-4733'}, 'institutions': [{'id': 'https://openalex.org/I45204951', 'display_name': 'University of Calabria', 'ror': 'https://ror.org/02rc97e94', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I45204951']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Patrizia D’Aquila', 'raw_affiliation_strings': ['Department of Biology, Ecology and Earth Science (DiBEST),University of Calabria, Arcavacata di Rende, Cosenza, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology, Ecology and Earth Science (DiBEST),University of Calabria, Arcavacata di Rende, Cosenza, Italy', 'institution_ids': ['https://openalex.org/I45204951']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5105874683', 'display_name': 'Riccardo Alessandro', 'orcid': 'https://orcid.org/0000-0002-9935-1040'}, 'institutions': [{'id': 'https://openalex.org/I900890020', 'display_name': 'University of Palermo', 'ror': 'https://ror.org/044k9ta02', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I900890020']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Riccardo Alessandro', 'raw_affiliation_strings': ['Department of Pathology and Forensic and Medical Biotechnology, Section of Biology and Genetics, University of Palermo, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology and Forensic and Medical Biotechnology, Section of Biology and Genetics, University of Palermo, Italy', 'institution_ids': ['https://openalex.org/I900890020']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5024798356', 'display_name': 'Antonio Giordano', 'orcid': 'https://orcid.org/0000-0002-5959-016X'}, 'institutions': [{'id': 'https://openalex.org/I84392919', 'display_name': 'Temple University', 'ror': 'https://ror.org/00kx1jb78', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I84392919']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Antonio Giordano', 'raw_affiliation_strings': ['Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, PA, USA'], 'affiliations': [{'raw_affiliation_string': 'Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, PA, USA', 'institution_ids': ['https://openalex.org/I84392919']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000930768', 'display_name': 'Pierosandro Tagliaferri', 'orcid': 'https://orcid.org/0000-0002-1535-2477'}, 'institutions': [{'id': 'https://openalex.org/I36443711', 'display_name': 'Magna Graecia University', 'ror': 'https://ror.org/0530bdk91', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I36443711']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Pierosandro Tagliaferri', 'raw_affiliation_strings': ['Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy', 'institution_ids': ['https://openalex.org/I36443711']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5077467836', 'display_name': 'Pierfrancesco Tassone', 'orcid': 'https://orcid.org/0000-0002-8298-6787'}, 'institutions': [{'id': 'https://openalex.org/I36443711', 'display_name': 'Magna Graecia University', 'ror': 'https://ror.org/0530bdk91', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I36443711']}, {'id': 'https://openalex.org/I84392919', 'display_name': 'Temple University', 'ror': 'https://ror.org/00kx1jb78', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I84392919']}], 'countries': ['IT', 'US'], 'is_corresponding': False, 'raw_author_name': 'Pierfrancesco Tassone', 'raw_affiliation_strings': ['Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy', 'Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, PA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy', 'institution_ids': ['https://openalex.org/I36443711']}, {'raw_affiliation_string': 'Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, PA, USA', 'institution_ids': ['https://openalex.org/I84392919']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 4.7, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 92, 'citation_normalized_percentile': {'value': 0.999894, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '5', 'issue': '10', 'first_page': '3039', 'last_page': '3054'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA in disease regulation', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA in disease regulation', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10649', 'display_name': 'Multiple Myeloma Research and Treatments', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11668', 'display_name': 'interferon and immune responses', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2780394083', 'wikidata': 'https://www.wikidata.org/wiki/Q539568', 'display_name': 'Angiogenesis', 'level': 2, 'score': 0.6725111}, {'id': 'https://openalex.org/C145059251', 'wikidata': 'https://www.wikidata.org/wiki/Q310899', 'display_name': 'microRNA', 'level': 3, 'score': 0.5652427}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.5380186}, {'id': 'https://openalex.org/C2776364478', 'wikidata': 'https://www.wikidata.org/wiki/Q467635', 'display_name': 'Multiple myeloma', 'level': 2, 'score': 0.502383}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.4944167}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.4649381}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.42185673}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.35413462}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.3277614}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.29814842}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.1635639}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.10249832}], 'mesh': [{'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D009101', 'descriptor_name': 'Multiple Myeloma', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D009389', 'descriptor_name': 'Neovascularization, Pathologic', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015153', 'descriptor_name': 'Blotting, Western', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002448', 'descriptor_name': 'Cell Adhesion', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D002448', 'descriptor_name': 'Cell Adhesion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015687', 'descriptor_name': 'Cell Hypoxia', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015687', 'descriptor_name': 'Cell Hypoxia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002465', 'descriptor_name': 'Cell Movement', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D002465', 'descriptor_name': 'Cell Movement', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004797', 'descriptor_name': 'Enzyme-Linked Immunosorbent Assay', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D066298', 'descriptor_name': 'In Vitro Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016688', 'descriptor_name': 'Mice, Inbred NOD', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016513', 'descriptor_name': 'Mice, SCID', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D009101', 'descriptor_name': 'Multiple Myeloma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009389', 'descriptor_name': 'Neovascularization, Pathologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060888', 'descriptor_name': 'Real-Time Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D023041', 'descriptor_name': 'Xenograft Model Antitumor Assays', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.1747', 'pdf_url': 'https://www.oncotarget.com/article/1747/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4102790', 'pdf_url': 'https://europepmc.org/articles/pmc4102790?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102790', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/20.500.12613/5321', 'pdf_url': 'https://scholarshare.temple.edu/bitstream/20.500.12613/5321/2/Targeting%20of%20multiple%20myeloma-related%20angiogenesis%20by%20miR-199a-5p%20mimics%20in%20vitro%20and%20in%20vivo%20anti-tumor%20activity.pdf', 'source': {'id': 'https://openalex.org/S4306402624', 'display_name': 'TUScholarShare (Temple University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I84392919', 'host_organization_name': 'Temple University', 'host_organization_lineage': ['https://openalex.org/I84392919'], 'host_organization_lineage_names': ['Temple University'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24839982', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.1747', 'pdf_url': 'https://www.oncotarget.com/article/1747/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.62, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 78, 'referenced_works': ['https://openalex.org/W1493048246', 'https://openalex.org/W1502976376', 'https://openalex.org/W1595061026', 'https://openalex.org/W1597321356', 'https://openalex.org/W1744006947', 'https://openalex.org/W1775236918', 'https://openalex.org/W1786491527', 'https://openalex.org/W1961631090', 'https://openalex.org/W1965338602', 'https://openalex.org/W1967222077', 'https://openalex.org/W1970714992', 'https://openalex.org/W1977381537', 'https://openalex.org/W1981218425', 'https://openalex.org/W1983953288', 'https://openalex.org/W1985130041', 'https://openalex.org/W1988605844', 'https://openalex.org/W1992304298', 'https://openalex.org/W1997667183', 'https://openalex.org/W2000763979', 'https://openalex.org/W2002995168', 'https://openalex.org/W2013187395', 'https://openalex.org/W2014272343', 'https://openalex.org/W2015732625', 'https://openalex.org/W2016138759', 'https://openalex.org/W2021377202', 'https://openalex.org/W2022095111', 'https://openalex.org/W2023858596', 'https://openalex.org/W2037624217', 'https://openalex.org/W2041690843', 'https://openalex.org/W2042748226', 'https://openalex.org/W2044305934', 'https://openalex.org/W2044455746', 'https://openalex.org/W2049702532', 'https://openalex.org/W2056120940', 'https://openalex.org/W2062123682', 'https://openalex.org/W2063421269', 'https://openalex.org/W2065726249', 'https://openalex.org/W2067680442', 'https://openalex.org/W2068439552', 'https://openalex.org/W2069759108', 'https://openalex.org/W2073666494', 'https://openalex.org/W2074621735', 'https://openalex.org/W2074887253', 'https://openalex.org/W2075533352', 'https://openalex.org/W2082055110', 'https://openalex.org/W2088161934', 'https://openalex.org/W2093787034', 'https://openalex.org/W2094251816', 'https://openalex.org/W2094636384', 'https://openalex.org/W2099896144', 'https://openalex.org/W2101559466', 'https://openalex.org/W2105772211', 'https://openalex.org/W2115397405', 'https://openalex.org/W2116000203', 'https://openalex.org/W2126569401', 'https://openalex.org/W2132217314', 'https://openalex.org/W2138344908', 'https://openalex.org/W2140639593', 'https://openalex.org/W2142723984', 'https://openalex.org/W2144897176', 'https://openalex.org/W2145156191', 'https://openalex.org/W2149821123', 'https://openalex.org/W2151371056', 'https://openalex.org/W2158575987', 'https://openalex.org/W2159726820', 'https://openalex.org/W2159856484', 'https://openalex.org/W2160618879', 'https://openalex.org/W2162180804', 'https://openalex.org/W2163406684', 'https://openalex.org/W2164239756', 'https://openalex.org/W2168057091', 'https://openalex.org/W2168074035', 'https://openalex.org/W2168181903', 'https://openalex.org/W2170945707', 'https://openalex.org/W2171544336', 'https://openalex.org/W2267969818', 'https://openalex.org/W3195431600', 'https://openalex.org/W4252175385'], 'related_works': ['https://openalex.org/W73242545', 'https://openalex.org/W638153814', 'https://openalex.org/W4210967366', 'https://openalex.org/W3152246802', 'https://openalex.org/W31401667', 'https://openalex.org/W2561802298', 'https://openalex.org/W2127463799', 'https://openalex.org/W2123707479', 'https://openalex.org/W2075734225', 'https://openalex.org/W2042474810'], 'abstract_inverted_index': {'//': [0, 157], 'Lavinia': [1], 'Raimondi': [2], '1': [3, 7, 13, 17, 21, 25, 29, 53, 59], ',': [4, 8, 14, 18, 22, 26, 30, 34, 38, 42, 46, 50], 'Nicola': [5], 'Amodio': [6], 'Maria': [9], 'Teresa': [10], 'Di': [11], 'Martino': [12], 'Emanuela': [15], 'Altomare': [16], 'Marzia': [19], 'Leotta': [20], 'Daniele': [23], 'Caracciolo': [24], 'Annamaria': [27], 'Gullà': [28], 'Antonino': [31], 'Neri': [32], '2': [33, 83], 'Simona': [35], 'Taverna': [36], '3': [37, 45, 97], 'Patrizia': [39], "D'Aquila": [40], '4': [41, 115], 'Riccardo': [43], 'Alessandro': [44], 'Antonio': [47], 'Giordano': [48], '5': [49, 131], 'Pierosandro': [51], 'Tagliaferri': [52], 'and': [54, 63, 69, 101, 103, 109, 120, 137, 146, 216, 271, 317, 328, 365], 'Pierfrancesco': [55, 154], 'Tassone': [56], '1,5': [57], '.': [58, 279], 'Department': [60, 84, 98, 116], 'of': [61, 85, 89, 99, 107, 112, 117, 124, 144, 206, 252, 258, 263, 292, 306, 321, 342, 363], 'Experimental': [62], 'Clinical': [64], 'Medicine,': [65, 139], 'Magna': [66], 'Graecia': [67], 'University': [68, 79, 88, 111], 'Medical': [70, 86, 104], 'Oncology': [71], 'Unit,': [72], 'T.': [73], 'Campanella': [74], 'Cancer': [75, 135], 'Center,': [76], 'Salvatore': [77], 'Venuta': [78], 'Campus,': [80], 'Catanzaro,': [81], 'Italy': [82, 96, 114, 130], 'Sciences': [87], 'Milan,': [90, 95], 'Hematology1,': [91], 'IRCCS': [92], 'Policlinico': [93], 'Foundation,': [94], 'Pathology': [100], 'Forensic': [102], 'Biotechnology,': [105, 142], 'Section': [106], 'Biology': [108], 'Genetics,': [110], 'Palermo,': [113], 'Biology,': [118], 'Ecology': [119], 'Earth': [121], 'Science': [122, 145], '(DiBEST),University': [123], 'Calabria,': [125], 'Arcavacata': [126], 'di': [127], 'Rende,': [128], 'Cosenza,': [129], 'Sbarro': [132], 'Institute': [133], 'for': [134, 141, 360, 383], 'Research': [136], 'Molecular': [138], 'Center': [140], 'College': [143], 'Technology,': [147], 'Temple': [148], 'University,': [149], 'Philadelphia,': [150], 'PA,': [151], 'USA': [152], 'Correspondence:': [153], 'Tassone,': [155], 'email:': [156], 'Keywords': [158], ':': [159, 172, 177, 182], 'miR-199-5p,': [160], 'microRNA,': [161], 'miRNA,': [162], 'multiple': [163], 'myeloma,': [164], 'plasma': [165], 'cell': [166], 'leukemia,': [167], 'microenviroment,': [168], 'hypoxia,': [169], 'angiogenesis': [170, 371], 'Received': [171], 'December': [173], '27,': [174], '2013': [175], 'Accepted': [176], 'March': [178, 183], '12,': [179], '2014': [180, 185], 'Published': [181], '14,': [184], 'Abstract': [186], 'Multiple': [187], 'myeloma': [188], '(MM)': [189], 'cells': [190, 276, 285, 294, 299, 308, 315], 'induce': [191], 'relevant': [192], 'angiogenic': [193, 207, 211], 'effects': [194], 'within': [195, 213], 'the': [196, 203, 214, 217, 290, 319, 361, 367], 'human': [197], 'bone': [198, 296], 'marrow': [199, 297], 'milieu': [200], '(huBMM)': [201], 'by': [202, 225], 'aberrant': [204], 'expression': [205, 251, 257, 320], 'factors.': [208], 'Hypoxia': [209], 'triggers': [210], 'events': [212], 'huBMM': [215], 'transcription': [218], 'factor': [219], 'hypoxia-inducible': [220], 'factor-1α': [221], '(HIF-1α)': [222], 'is': [223], 'over-expressed': [224], 'MM': [226, 244, 275, 284, 293, 307, 347, 364], 'cells.': [227, 245, 348], 'Since': [228], 'synthetic': [229], 'miR-199a-5p': [230, 253, 281, 310, 343, 355], 'mimics': [231], 'negatively': [232, 282], 'regulates': [233], 'HIF-1α,': [234], 'we': [235, 331], 'here': [236], 'investigated': [237], 'a': [238, 333, 337, 373, 378], 'miRNA-based': [239], 'therapeutic': [240], 'strategy': [241], 'against': [242], 'hypoxic': [243, 274, 302, 346], 'We': [246], 'indeed': [247], 'found': [248], 'that': [249, 354, 369], 'enforced': [250], 'led': [254], 'to': [255, 295], 'down-modulated': [256], 'HIF-1α': [259], 'as': [260, 262, 268, 326, 336], 'well': [261], 'other': [264], 'pro-angiogenic': [265], 'factors': [266], 'such': [267, 325], 'VEGF-A,': [269], 'IL-8,': [270], 'FGFb': [272], 'in': [273, 277, 301, 345], 'vitro': [278], 'Moreover,': [280], 'affected': [283], 'migration,': [286], 'while': [287], 'it': [288], 'increased': [289], 'adhesion': [291, 323], 'stromal': [298], '(BMSCs)': [300], 'conditions.': [303], 'Furthermore,': [304], 'transfection': [305], 'with': [309], 'significantly': [311], 'impaired': [312], 'also': [313], 'endothelial': [314, 322], 'migration': [316], 'down-regulated': [318], 'molecules': [324], 'VCAM-1': [327], 'ICAM-1.': [329], 'Finally,': [330], 'identified': [332], 'hypoxia\\AKT/miR-199a-5p': [334], 'loop': [335], 'potential': [338, 380], 'molecular': [339], 'mechanism': [340], 'responsible': [341], 'down-regulation': [344], 'Taken': [349], 'together': [350], 'our': [351], 'results': [352], 'indicate': [353], 'has': [356], 'an': [357], 'important': [358], 'role': [359], 'pathogenesis': [362], 'support': [366], 'hypothesis': [368], 'targeting': [370], 'via': [372], 'miRNA/HIF-1α': [374], 'pathway': [375], 'may': [376], 'represent': [377], 'novel': [379], 'therapeutical': [381], 'approach': [382], 'this': [384], 'still': [385], 'lethal': [386], 'disease.': [387]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1905499183', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 7}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 8}, {'year': 2019, 'cited_by_count': 10}, {'year': 2018, 'cited_by_count': 11}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 13}, {'year': 2015, 'cited_by_count': 20}, {'year': 2014, 'cited_by_count': 3}], 'updated_date': '2024-12-08T11:23:38.546516', 'created_date': '2016-06-24'}