Title: Longitudinal effects of anxiety and depression on physical activity in COPD patients
Abstract:COPD patients have reduced levels of physical activity (PA) and a high prevalence of anxiety and depression, but the relationship between these variables is poorly understood. Main objective: To asses...COPD patients have reduced levels of physical activity (PA) and a high prevalence of anxiety and depression, but the relationship between these variables is poorly understood. Main objective: To assess the longitudinal effects of anxiety and depression on PA in COPD patients. Methods: We recruited 236 COPD patients from 5 European countries and followed them for 1 year (EU IMI PROactive project). Anxiety and depression symptoms (using the Hospital Anxiety Depression Scale), PA measures (with DynaPort ® accelerometer), socio-demographic characteristics, lung function tests, bioimpedance and exercise capacity (6MWD) were evaluated at baseline, and at 6 and 12 months. We built multivariate linear regression models with repeated measures to assess the association of anxiety/depression (at baseline and 6 months) with PA (at 6 and 12 m). Results: Patients (age 67(8)y, FEV1 57(21)%) showed a prevalence of depression and anxiety (HADS depression and anxiety scores≥11 points) of 6% and 12%, respectively. Patients with depression performed fewer steps/day (1894 vs 4143, p Conclusions: In patients with COPD, symptoms of depression are associated with less PA six months later. No longitudinal effect of anxiety on PA was found. Funding : Innovative Medicines Initiative Joint Undertaking (IMU-JU #115011).Read More
Publication Year: 2014
Publication Date: 2014-09-01
Language: en
Type: article
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