Publication Information

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324, 366, 614, 692, 840, 1073, 1295, 1311, 1350, 1474, 1516, 1555, 1633, 1682, 1740, 1746, 1828, 1874, 1944, 1964, 1975, 1984, 2026, 2052, 2074, 2122, 2275, 2293, 2341, 2372, 2500, 2557, 2632, 2835, 2840, 2857, 2880], 'no': [66, 237, 255, 400, 659, 702, 706, 740, 1129, 1272, 1277, 1737, 2267, 2284, 2346, 2497], 'past': [67], 'illness': [69, 1432, 1481, 1624], 'who': [70, 2375], 'presented': [71, 86, 1349], 'several': [73], 'days': [74, 390, 532, 906, 1161, 1636], 'disorganized': [76, 1023], 'behavior.History': [77], 'Present': [79, 173, 511], 'illnessNine': [80], 'months': [81, 121, 1241, 1258, 1261, 1339, 1380, 1712, 2205], 'earlier,': [82], 'patient': [84, 128, 538, 596, 714, 909, 934, 1019, 1077, 1133, 1151, 1270, 1348, 1370, 1402, 1754, 1970, 2839, 2879], 'had': [85, 550, 631, 710, 718, 722, 727, 971, 1045, 1053, 1088, 1276, 1281, 1299, 1504], 'her': [88, 99, 124, 610, 829, 841, 1003, 1093, 1195, 1211, 1233, 1283, 1289, 1302, 1344, 1384, 1389, 1397, 1419, 1705, 2164, 2246], 'primary': [89, 1702, 1792, 1858], 'care': [90, 2110, 2427, 2787, 2902, 2938], 'provider': [91], 'mild': [93, 671], 'neurological': [94, 664, 1952, 2126], 'complaints.': [95], 'The': [96, 663, 810, 925, 933, 1076, 1150, 1774, 2336, 2763], 'course': [97, 1534, 1672], 'physical': [100], 'symptoms': [101, 521, 1154, 1247, 1353, 1385, 1468, 1506, 1509, 1562, 1570, 1604, 1679, 1787, 1849, 1883, 1941, 2009, 2200, 2295, 2309, 2378, 2389, 2593], 'laboratory': [103], 'tests': [104, 781], 'leading': [105, 1444], 'diagnosis': [108, 842, 892, 1547, 1798, 2983], 'disease': [111, 296, 845, 1122, 1314, 1427, 1495, 1518, 1537, 1557, 1565, 1825, 1852, 1862, 1966, 2028, 2076, 2127, 2149, 2313, 2340, 2374, 2392, 2406, 2516, 2555, 2630, 2672, 2792, 2994], 'are': [112, 300, 1580, 2003, 2045, 2079, 2266, 2315], 'summarized': [113], 'Table': [115], '1,': [116, 1156, 1217, 1257, 1316, 3048], 'entries': [119], '0–8.': [122], 'For': [123], 'disease,': [126, 1476, 2279, 2653], 'started': [130, 1183], 'on': [131, 267, 557, 1184, 1221, 1227, 2081, 2189, 2910, 2992, 3077], 'combination': [133], 'copper': [136, 280, 289, 479, 485, 837, 854, 863, 1305, 1449, 1616, 1868, 2220], 'chelator': [137], 'trientine': [138, 167, 1110], 'zinc.': [140], 'She': [141, 549, 566, 574, 602, 630, 639, 709, 721, 963, 1012, 1034, 1044, 1083, 1095, 1181, 1409], 'soon': [142], 'developed': [143, 921, 950, 1027, 1084, 1152, 1971], 'colitis,': [144, 159], 'which': [145, 523, 919, 1037, 1761, 1986, 2131], 'thought': [147, 305, 547, 637, 1203, 1243, 1595, 1692], 'be': [149, 569, 605, 966, 1022, 2089, 2145, 2229, 2241, 2322, 2429], 'side': [151, 1738, 1771, 1953, 1973, 2334], 'effect': [152, 2909], 'trientine.': [155, 330], 'To': [156], 'treat': [157], 'prednisone': [160, 534, 1185, 1639], 'initiated': [162, 1146], 'at': [163, 351, 554, 562, 1016, 1147, 1186, 1461, 1529, 1573, 1864, 2408], '40': [164, 333], 'mg/day,': [165, 334, 397, 411, 948, 1001, 1072], 'discontinued.TABLE': [169], '1.': [170, 508], 'History': [171, 509, 3248], 'Illness': [174, 512], 'Patient': [177, 515], 'With': [178, 516], 'DiseaseaSigns': [180], 'SymptomsMedicationsTimePsychiatricNeurologicalGastrointestinal': [182], 'HepaticLaboratory': [184], 'Imaging': [186], 'ResultsGeneralPsychotropicMonth': [187], '0NoneTingling': [188], 'tongue,': [190], 'lips,': [191], 'fingertipsNoneBrain': [192], 'MRI': [193, 235, 246, 870], 'shows': [194, 236], 'diffuse': [195], 'area': [196], 'increased': [198, 542, 875, 945, 1069], 'T2': [199], 'signal': [200, 876], 'white': [203, 216, 883], 'matter': [204, 884], 'pons': [207], 'midbrain,': [210], 'extending': [211], 'into': [212], 'midline': [214], 'cerebellar': [215], 'matterNoneNoneMonth': [217], '1DepressionAll': [218], 'above': [220, 260], 'plus': [221, 261], 'decreased': [222, 415, 1648], 'taste,': [223], 'perioral': [224], 'burning,': [225], 'drooling,': [226], 'gait': [227], 'unsteadiness,': [228], 'bladder': [229], 'urgency': [230], 'hesitancyNoneEMG': [232], 'studies': [233, 838, 1610, 2286], 'normal;': [234, 247], 'interval': [238], 'change': [239], 'brain': [242, 869], 'lesions;': [243], 'cervical': [244], 'spine': [245], 'lumbar': [248], 'puncture': [249], 'results': [250], 'normalNoneCitalopram': [251], '1': [253, 461, 1190, 3263, 3269], 'month,': [254, 1210, 1676], 'effect,': [256], 'discontinuedMonth': [257], '8NoneAll': [258], 'weakness': [262], 'all': [264], 'extremities.': [265], 'Paresthesias': [266], 'head,': [268], 'slowed': [269], 'speech,': [270, 1661], 'cognitive': [271, 645, 1759, 2343], 'slowingNoneCeruloplasmin': [272], 'level': [273, 765, 793, 799, 806, 813, 855, 864], '<2': [274, 849], 'mg/dL': [275], '(ref.': [276, 284, 293], 'range,': [277, 285, 294], '14–47.8);': [278], 'serum': [279, 478, 747, 853], 'level,': [281, 290, 475, 480, 486], '0.25': [282, 857], 'μg/dL': [283, 292], '0.75–1.45);': [286], '24-hour': [287, 483, 861], 'urine': [288, 484], '187': [291, 866], "15–60)NoneNoneWilson's": [295], 'diagnosisTrientine': [297], 'zinc': [299, 1056, 1117, 1414], 'initiatedMonth': [301], '8.5Psychosis': [302], '(delusions,': [303], 'grandiosity,': [304], 'disorder);': [306], 'BPRS,': [307, 373, 378, 449, 473, 493], '91': [308], '→': [309], '55Limitation': [310], 'upward': [312, 669], 'gaze,': [313, 670], 'ptosis,': [314, 672], 'neck': [315, 691, 923], 'tilt': [316, 688], 'chin': [318, 694], 'down': [319, 695], 'leftDiarrhea': [323], 'blood': [325], 'stools': [327], 'secondary': [328, 1801], 'Diarrhea': [331], 'resolvedPrednisone,': [332], 'trientine-induced': [336, 1175], 'colitis.': [337], 'Trientine': [338], 'discontinued.': [339, 408, 1336, 1992], 'Prednisone': [340, 898], 'discontinued.Olanzapine,': [341], 'one': [342, 912], 'dose,': [343], '2.5': [344, 916], 'mg;': [345], 'discontinued': [346, 928, 1142, 1382], 'because': [347, 419, 2150, 2244], 'dystonia.': [349, 924], 'Quetiapine': [350, 407, 423, 2854], '50': [352, 495, 947], 'mg': [353, 465], 'h.s.': [354], 'induced': [355], 'hypotension;': [356], 'dosage': [357, 943, 957, 998, 1067, 1749, 2016], 'decreased,': [359], 'then': [360], 'titrated': [361, 425, 994], 'slowly': [362, 444, 1248, 2243], '400': [364, 1071], 'mg,': [365, 496, 917], 'intermittent': [367, 1074], 'adherenceMonth': [368], '10Psychosis': [369], 'worsening,': [370], 'Capgras': [371, 1085, 1687], 'syndrome;': [372], '78.': [374], 'Psychosis': [375, 1525, 2611, 3017], 'starts': [376], 'resolving;': [377, 445], '58Severe': [379], 'parkinsonism:': [380], 'shuffling': [381], 'gait,': [382], 'cogwheeling,': [383], 'bradykinesia,': [384], 'drooling': [385], '(haloperidol': [386], 'induced)Diarrhea': [387], 'returns': [388], '3': [389, 476, 531, 1040, 1322, 1394, 2254], 'after': [391, 533, 918, 1042, 1123, 1262, 1340, 1388, 1396, 1637, 1713, 1729, 1989, 2203, 2439], 'resuming': [392], 'trientineTrientine': [393], 'resumed.': [394], 'Prednisone,': [395], '10': [396, 1187], 'colitis;': [399], 'exacerbation': [401], 'psychosisPsychiatric': [403], 'hospitalization,': [404, 1164], '4': [405, 1160], 'days.': [406, 413], 'Haloperidol,': [409], '20': [410, 1148], '5': [412, 417, 989, 1240, 3254], 'Haloperidol': [414], 'mg/day': [418, 937, 1188], 'parkinsonian': [421, 1153, 1246], 'symptoms.': [422, 2172], 'reintroduced,': [424], '150': [427, 470], 'mg/day.': [428, 433, 962, 1149], 'Benztropine,': [429], 'up': [430, 553], '2': [432, 455, 598, 905, 1063], 'Lorazepam': [434], 'initially': [435, 1220], 'insomnia,': [437, 541], 'later': [438, 1226], 'changed': [439], 'clonazepamMonths': [441], '11–16Tangential': [442], 'speech': [443], 'insomnia.': [446], 'No': [447, 2640], 'delusions;': [448], '51Parkinsonism': [450], 'improvingZincHaloperidol': [451], 'tapered': [452, 458, 490, 900, 1326, 1334], 'off': [453, 459, 901, 1047, 1406], 'over': [454, 460, 902, 1764], 'weeks;': [456], 'benztropine': [457], 'month.': [462], 'Clonazepam,': [463], '0.5': [464], 'twice': [466], 'day.': [468], 'Quetiapine,': [469], 'mg/dayMonth': [471], '17Resolved;': [472], '27ResolvedCeruloplasmin': [474], 'mg/dL;': [477], '0.12': [481], 'μg/dL;': [482], '49': [487], 'μg/LZincQuetiapine,': [488], 'clonazepam': [489, 1253, 1324], 'offMonth': [491], '21Depression;': [492], '29NoneZincSertraline,': [494], '6': [497, 1050, 1379, 1727], 'months,': [498, 1323], 'good': [499, 1779], 'resultsMonths': [500], '27–56None;': [501], 'BPRS': [502], '24NoneZincNoneaBPRS=Brief': [503], 'Rating': [505], 'Scale;': [506], 'EMG=electromyography.TABLE': [507], 'DiseaseaEnlarge': [518], 'tableThe': [519], 'formal': [525, 644], 'evaluation': [526, 665, 1392, 2913], 'began': [529, 539, 1199], 'approximately': [530], 'started:': [536], 'exhibiting': [540], 'energy,': [543, 1647], 'delusions': [545, 635, 1683], 'control.': [548], 'been': [551, 728, 1046, 1300, 1470, 1483, 1527, 1541, 1855, 1911, 1960, 2112, 2213, 2283, 2443], 'staying': [552], 'night': [555], 'working': [556, 729], 'two': [558, 719], 'computers': [559], 'cooking': [561], 'same': [564], 'time.': [565], 'claimed': [567, 980], 'famous': [571], 'movie': [572], 'star.': [573], 'admitted': [576], 'via': [577], 'emergency': [579], 'department': [580], 'medical': [583, 1223, 1590, 1804, 1900, 2032, 2054, 2083, 2141, 2355], 'service.Mental': [584], 'Status': [585], 'Examination': [586], 'Pertinent': [588], 'Physical': [589], 'FindingsOur': [590], 'team': [593, 2055], 'examined': [594], 'within': [597, 751, 1635, 1726], 'hours': [599], 'admission.': [601], 'appeared': [603], 'groomed': [607], 'looking': [609], 'stated': [611], 'age,': [612], 'hyperactive,': [613], 'bizarre': [615], 'movements': [616], 'that': [617, 1479, 1596, 1644, 1697, 1823, 2002, 2041, 2234, 2318, 2365], 'she': [618, 648, 735, 920, 949, 981, 1007, 1026, 1165, 1298], 'called': [619, 1484], '"my': [620], 'special': [621], 'dance."': [622], 'Her': [623, 822, 1197, 1202, 1286, 1304], 'affect': [624], 'excessive,': [626], 'bizarre,': [627], 'labile.': [629], 'loose': [632], 'associations': [633], 'insertion.': [638], 'could': [640, 2239], 'not': [641, 1567, 1581, 1700, 1756, 2046], 'participate': [642], 'testing,': [646], 'but': [647, 2225], 'oriented': [650], 'person,': [652], 'time,': [653, 1499, 2319], 'place': [655], 'there': [657, 1735, 2281], 'were': [658, 750, 782, 846, 1214, 1254, 1309, 1668, 1699, 1716, 1736, 2086], 'fluctuations': [660], 'alertness.': [662], 'revealed': [666], 'limitation': [667], 'reduced': [673, 681, 959], 'blink': [674], 'frequency,': [675], 'axial': [676], 'rigidity': [677], 'neck,': [680], 'smooth-pursuit': [682], 'eye': [683], 'movements,': [684], 'slight': [687], 'left.': [699], 'There': [700, 738, 2265], 'glabellar': [703], 'reflex,': [704], 'cogwheel': [707], 'rigidity.': [708], 'Kayser-Fleischer': [711], 'rings.Psychosocial': [712], 'HistoryThe': [713], 'married': [716], 'children.': [720], 'completed': [723], 'postgraduate': [724], 'education': [725], 'as': [730, 1290, 1292, 1297, 1415, 1659, 1923, 1925, 2011, 2180, 2480, 2486], 'freelance': [732, 1284], 'designer': [733], 'until': [734], 'became': [736, 1008, 1035, 1680], 'ill.': [737], 'family': [741, 1287, 2161], 'history': [742], 'illness.Laboratory': [745], 'DataBasic': [746], 'chemistry': [748], 'values': [749], 'normal': [752, 785], 'limits.': [753], 'CBC': [754], 'notable': [756, 783], 'WBC': [759], 'count': [760, 776], '13.5×1000/μL,': [762], 'hemoglobin': [764], '13.3': [767], 'g/dL,': [768], 'hematocrit': [770], '40.1%,': [772], 'platelet': [775], '345×1000/μL.': [778], 'Liver': [779, 3003], 'functions': [780], 'direct': [786], 'total': [788, 818, 852, 997, 2380], 'bilirubin': [789], 'levels,': [790], 'an': [791, 797, 804, 1228, 1429, 1879, 2487], 'AST': [792], '47': [795], 'U/L,': [796, 802], 'ALT': [798], '159': [801], 'ALP': [805], '185': [808], 'U/L.': [809], "patient's": [811, 1627, 2236], 'albumin': [812], '3.1': [815], 'g/dL': [816], 'protein': [819], '6.7': [820], 'g/dL.': [821], 'prothrombin': [823], 'time': [824], '11.8': [826], 'seconds,': [827], 'INR': [830], '(international': [831], 'normalized': [832], 'ratio)': [833], '1.12.': [835], 'Repeated': [836], 'consistent': [839, 1310], 'ceruloplasmin': [847, 1307], 'levels': [848, 1308, 2221], 'mg/dL,': [850], 'μg/dL,': [858], 'urinary': [862], 'μg.': [867], 'A': [868, 2511], 'showed': [871, 1128, 1271], 'nonspecific': [872], 'foci': [873], 'last': [879, 1398], 'centrum': [880], 'semiovale': [881], 'right': [887], 'parietal': [888], 'lobe.Treatment': [889], 'CourseA': [890], 'presumptive': [891], 'steroid-induced': [894, 1631, 1723, 1769], 'psychosis': [895, 1234, 1710, 1800, 2421, 2770, 2815], 'made.': [897], 'next': [904, 1062, 1209, 1239], 'given': [911], 'dose': [913], 'olanzapine,': [915], 'significant': [922, 1972], 'olanzapine': [926], 'quetiapine': [930, 992, 1066, 1140, 1251, 1332], 'started.': [932], 'tolerated': [935], '25': [936], 'quetiapine,': [939, 1919], 'although': [940], 'when': [941, 1383, 2077, 2306, 2419], 'orthostatic': [951], 'hypotension': [952], 'sedation,': [954], '12.5': [961], 'continued': [964, 1020, 1054, 1255, 1411], 'psychotic': [967, 1267, 1345, 1678, 1793, 2377], 'grandiose': [969], '(she': [970], 'plans': [972], 'buy': [974], '$50,000': [975], 'worth': [976], 'stocks': [978], 'CEO': [984], 'company).': [987], 'Over': [988, 1060, 1207, 1670], 'days,': [990], '75': [1000], 'condition': [1005, 1805], 'improved:': [1006], 'calmer': [1009], 'cooperative.': [1011], 'discharged': [1014], 'home.While': [1015], 'home,': [1017], 'tangential;': [1025], 'paranoid': [1028, 2634], 'delusions,': [1029], 'hallucinations,': [1030], 'pressured': [1032, 1660], 'speech.': [1033], 'aggressive,': [1036], 'prompted': [1038], 'readmission': [1039], 'weeks': [1041, 1051, 1728, 1988], 'discharge.': [1043], 'steroids': [1048, 1698, 1715, 1732], 'disease.': [1059, 1904, 2264, 2614, 2818, 2859, 2882], 'weeks,': [1064], 'adherence.': [1075], 'remained': [1078, 1205, 1404], 'disorganized,': [1079], 'incoherent,': [1080], 'paranoid.': [1082], 'syndrome': [1086, 2635, 2876], 'vague': [1089], 'thoughts': [1090], 'hurting': [1092], 'family.': [1094], 'deemed': [1097], 'psychiatrically': [1098], 'disabled': [1099], 'committed': [1102], 'unit.': [1107, 2084], 'In': [1108, 1319, 1489], 'parallel,': [1109], 'resumed': [1112, 1282], 'added': [1114], 'treatment': [1119, 1417, 1836, 1845, 1859, 1873, 2020, 2095, 2261, 2274, 2369, 2912], 'sigmoidoscopy': [1125], 'biopsy': [1127], 'active': [1130, 2031], 'colitis.After': [1131], 'transferred': [1135], 'unit,': [1139], 'haloperidol': [1144, 1990], '(Table': [1155, 1216, 1256, 1315], 'month': [1157, 1218, 1317], '10).': [1158], 'After': [1159], 'returned': [1166], 'bloody': [1172], 'diarrhea,': [1173], 'colitis': [1176], 'confirmed': [1178], 'endoscopy.': [1180], 'week,': [1191], 'without': [1192, 2256], 'worsening': [1193], 'psychosis.': [1196], 'paranoia': [1198], 'resolve.': [1201], 'process': [1204], 'tangential.': [1206], 'psychotropic': [1212, 1407, 1887, 1908, 1957, 2237, 2257, 2327, 2398, 2440], 'medications': [1213, 1909, 1958, 2238, 2258, 2328, 2399, 2441], 'adjusted': [1215, 2242], '10),': [1219], 'unit': [1224], 'outpatient': [1229, 2098], 'basis,': [1230], 'address': [1232, 1894], 'haloperidol-induced': [1236], 'parkinsonism.Over': [1237], 'disorder': [1244], 'resolved': [1249], 'while': [1250, 2259], '11–16).': [1259], 'Nine': [1260], 'start': [1264, 1575], 'symptoms,': [1268, 1279], 'evidence': [1273], 'psychosis,': [1275, 1778, 2654], 'mood': [1278], 'work.': [1285], 'described': [1288, 1471, 1528], 'being': [1291, 1553, 1685], 'fully': [1293, 1582], 'engaged': [1294], 'them': [1296], 'before': [1301, 1552], 'illness.': [1303, 1707], 'treated': [1312, 2834], '17).': [1318], 'subsequent': [1321], 'discontinued,': [1328, 1717], 'shortly': [1330], 'thereafter,': [1331], 'Approximately': [1337], '13': [1338], 'beginning': [1342], 'episode,': [1346, 1400], 'moderate': [1351], 'depressive': [1352, 1399], 'triggered': [1354], 'realization': [1357], '"time': [1360], 'lost': [1361], 'due': [1362, 2214], 'big': [1365], 'W"': [1366], '(the': [1367], 'nickname': [1368], 'uses': [1371], 'disease).': [1374], 'Sertraline': [1375], 'prescribed': [1377], 'resolved.Four': [1386], 'years': [1387, 1395, 1551, 2255, 2438], 'initial': [1390, 1628], 'has': [1403, 1410, 1469, 1482, 1526, 2478], 'asymptomatic': [1405], 'medications.': [1408], 'take': [1413], 'maintenance': [1416], 'disease.DiscussionBackground:': [1421], 'Manifestations': [1423, 1815], "DiseaseWilson's": [1426], 'is': [1428, 1459, 1566, 1820, 1832, 1891, 2021, 2056, 2345, 2379, 2422], 'autosomal': [1430], 'recessive': [1431], 'attributed': [1433], 'defect': [1436], 'gene': [1439], 'ATP7B': [1440], '(on': [1441], 'chromosome': [1442], '13)': [1443], 'excessive': [1446], 'accumulation': [1447, 2412], 'liver,': [1451], 'brain,': [1452, 2224], 'other': [1454, 1618], 'tissues.': [1455], 'Its': [1456], 'lifetime': [1457], 'prevalence': [1458, 1513, 2154], 'estimated': [1460], '1:30,000': [1462], '(1).A': [1463], 'vast': [1464], 'range': [1465], 'patients': [1473, 1515, 1544, 1853, 1943, 1963, 2073, 2121, 2371, 2433], 'so': [1477], 'many': [1478], '"a': [1485], 'great': [1486, 2538], 'masquerader"': [1487], '(2).': [1488], '1912': [1491], 'monograph': [1492], 'describing': [1493], 'first': [1498, 1675], 'eight': [1500], '12': [1502, 3237], 'cases': [1503, 1721, 1767, 2740], '(3).': [1507], 'have': [1510, 1540, 1611, 1854, 1910, 1959, 2030, 2111, 2212, 2282, 2442], 'higher': [1512], 'among': [1514], 'than': [1519], 'general': [1522], 'population': [1523], '(4).': [1524], 'various': [1530, 1602, 1907], 'points': [1531], '(5–8).': [1538], 'Cases': [1539], 'reported': [1542, 1961, 2113], 'carrying': [1545], 'schizophrenia': [1549, 1621], 'diagnosed': [1554], '(9).The': [1558], 'mechanism': [1559], 'clear.': [1568], 'Because': [1569], 'can': [1571, 2185], 'occur': [1572, 1762], 'illness,': [1578], 'they': [1579, 2078], 'explained': [1583], 'psychosocial': [1586, 1781], 'impact': [1587], 'condition.': [1591], 'Initially': [1592], 'it': [1593, 1819, 2226], 'basal': [1597], 'ganglia': [1598], 'abnormalities': [1599], 'led': [1600], 'through': [1605], 'dopamine': [1606], 'dysregulation.': [1607], 'More': [1608], 'recent': [1609], 'explored': [1612], 'role': [1614, 2071], 'microelements': [1619], 'bipolar': [1623, 2716], '(10,': [1625], '11).Our': [1626], 'presentation': [1629], 'suggested': [1630], 'mania,': [1632], 'onset': [1634, 1776], 'starting': [1638], 'clinical': [1642, 1842], 'picture': [1643], 'included': [1645], 'elevated': [1646], 'need': [1649], 'sleep,': [1651], 'grandiosity.': [1653], 'Other': [1654], 'manic': [1655], 'features,': [1656], 'however,': [1657], 'such': [1658, 2179], 'flight': [1662], 'ideas,': [1664], 'psychomotor': [1666], 'agitation,': [1667], 'lacking.': [1669], 'predominant,': [1681], 'controlled,': [1686], 'syndrome,': [1688], 'posturing,': [1689], 'tangential': [1691], 'process.': [1693], 'Three': [1694], 'factors': [1695], 'suggest': [1696], 'cause': [1703, 2007], 'First,': [1708], 'persisted': [1711], 'whereas': [1718], '90%': [1719], 'mania': [1724, 2856], 'resolve': [1725, 2310], 'discontinuation': [1730], '(12).': [1733], 'Second,': [1734], 'effects': [1739, 1772, 1954, 1974], 'second': [1742], 'steroid': [1743, 2769], 'challenge': [1744], '(albeit': [1745], 'lower': [1748], 'prednisone).': [1751], 'Third,': [1752], 'our': [1753, 1994, 2035, 2101, 2158, 2195], 'did': [1755], 'exhibit': [1757], 'any': [1758], 'deficits,': [1760], '70%': [1765], 'neuropsychiatric': [1770, 2764], '(13).': [1773], 'late': [1775], 'premorbid': [1780], 'functioning,': [1782], 'lack': [1784], 'prodromal': [1786], 'militate': [1788], 'against': [1789], 'chronic': [1791, 2905], 'disorder,': [1794], 'therefore': [1796], "(Wilson's": [1806], 'disease)': [1807], 'formally': [1809], 'established.Treatment': [1810], 'Prognosis': [1812], 'DiseaseAlthough': [1818], 'well': [1821, 1924], 'recognized': [1822], 'often': [1826, 2044], 'presents': [1827], 'problems,': [1830], 'little': [1831], 'known': [1833], 'about': [1834], 'or': [1837, 1872, 1889], 'prognosis': [1839], 'these': [1841, 2063], 'manifestations.': [1843], 'Two': [1844], 'approaches': [1846], 'described:': [1856], '1)': [1857], 'directed': [1863, 2407], 'removal': [1865, 2415], 'pathological': [1867], 'deposition': [1869], '(chelation': [1870], 'therapy': [1871, 1901, 2356, 2403, 2812], 'zinc)': [1875], 'alone': [1876], 'leads': [1877], 'improvement': [1880], '(14,': [1884], '15);': [1885], '2)': [1886], 'medication': [1888], 'psychotherapy': [1890], 'used': [1892], 'specific': [1895], 'presentations': [1897], 'independent': [1898], 'Trials': [1905], 'reported,': [1912], 'including': [1913], 'lithium,': [1914], 'haloperidol,': [1915, 1985], 'tricyclic': [1916], 'antidepressants,': [1917], 'benzodiazepines,': [1918], 'risperidone,': [1920], 'clozapine,': [1922], 'trials': [1926], 'ECT': [1928], '(4,': [1929], '8,': [1930, 3113], '16,': [1931, 3235], '17).Our': [1932], 'case': [1933, 1995, 2036, 2361], 'illustrates': [1934], 'three': [1935], 'important': [1936], 'aspects': [1937, 2572], 'treating': [1939], 'disease.Sensitivity': [1946], 'antipsychotic': [1948], 'medications.High': [1949], 'incidences': [1950], 'caused': [1955], '(e.g.,': [1967], '18).': [1968], 'Our': [1969, 2360], 'minimal': [1976], 'dosages': [1977], 'atypical': [1979], 'antipsychotics': [1980, 2001], 'severe': [1982, 2420], 'parkinsonism': [1983], 'lasted': [1987], 'Thus,': [1993], 'supports': [1996, 2362], 'practice': [1998], 'selecting': [2000], 'less': [2004], 'likely': [2005], 'extrapyramidal': [2008], '(such': [2010], 'quetiapine)': [2012], 'titrating': [2014], 'slowly.The': [2017], 'setting': [2018], 'where': [2019], 'provided': [2022], 'symptoms.Patients': [2025], 'may': [2029, 2211, 2227, 2393, 2434], 'problems': [2033], '(in': [2034], 'ileitis-colitis)': [2037], 'requiring': [2038], 'prompt': [2039], 'management': [2040, 2061, 2789, 2985, 3169], 'units': [2043, 3162], 'equipped': [2047], 'provide.': [2049], 'Close': [2050], 'collaboration': [2051], 'essential': [2057], 'long-term': [2060, 2333], 'patients.': [2064, 2675], 'Often': [2065], 'psychiatrist': [2067], 'consultative': [2070], 'follows': [2072], 'hospitalized': [2080], 'We': [2085, 2299], 'fortunate': [2087], 'able': [2090], 'continue': [2092], 'multidisciplinary': [2094, 2979], 'setting,': [2099], 'Disease': [2103, 2183, 2460, 3090, 3124], 'Center': [2104, 2461], 'Excellence.': [2106], 'Co-located': [2107], 'models': [2108], 'improve': [2115, 3168], 'quality': [2117, 2934], 'life': [2119], 'liver': [2123], '(19)': [2124], '(20).': [2128], 'This': [2129, 2208], 'model,': [2130], 'implies': [2132], 'presence': [2134], 'mental': [2136, 2936], 'health': [2137, 2937], 'professionals': [2138], 'clinic,': [2142], 'needs': [2143], 'considered': [2146], 'high': [2153], 'symptoms.For': [2157], 'patient,': [2159, 2196], 'strong': [2160], 'support': [2162, 2177], 'allowed': [2163], 'avoid': [2166], 'extended': [2167], 'hospitalization': [2168], 'despite': [2169], 'disabling': [2170], 'Psychoeducation': [2173], 'and/or': [2174], 'referral': [2175, 3165], 'organizations,': [2178], 'Wilson': [2182, 2459, 2492, 2574, 2956, 2987, 2993, 3171], 'Association,': [2184], 'ease': [2186], 'burden': [2188], 'caregivers.Duration': [2190], 'goal': [2192, 2367], 'treatment.For': [2194], 'remission': [2197, 2381, 2436], 'achieved': [2202], '9': [2204], 'treatment.': [2207], 'slow': [2209, 2217], 'recovery': [2210], 'reduction': [2218], 'also': [2228], 'attributable': [2230], 'fact': [2233], 'only': [2240], 'sensitivity.Full': [2247], 'remission,': [2248], 'once': [2249], 'achieved,': [2250], 'maintained': [2252], 'continuing': [2260], 'data': [2268], 'guide': [2270], 'duration': [2272], 'psychotropics': [2276], 'since': [2280, 2432], 'systematic': [2285], 'correlation': [2289], 'biological': [2291], 'markers': [2292, 2314], 'disorder.': [2298, 2359, 2717], 'advocate': [2300], 'close': [2301], 'ongoing': [2302], 'observation': [2303], 'identify': [2305], 'normalized.': [2316], 'At': [2317], 'attempts': [2320], 'should': [2321, 2401, 2428], 'made': [2323], 'discontinue': [2325], 'reduce': [2330], 'short-': [2331], 'effects.': [2335], 'association': [2337], 'irreversible': [2342], 'decline': [2344], 'longer': [2347], 'rule': [2349], 'context': [2352], 'effective': [2354], 'notion': [2364], 'develop': [2376], 'return': [2383], 'previous': [2385], 'functioning.ConclusionsTreatment': [2386], 'require': [2394], 'slower': [2395], 'titration': [2396], 'accompany': [2402], 'prevention': [2410], 'copper.': [2417], 'Even': [2418], 'present,': [2423], 'aim': [2425], 'full': [2430], 'recovery,': [2431], 'maintain': [2435], 'discontinued.From': [2444], 'Departments': [2446], 'Psychiatry': [2448, 2580, 2599, 2676, 2886, 3225], 'Internal': [2450], 'Medicine,': [2451, 2456], 'Yale': [2452, 2464], 'University': [2453, 2465], 'School': [2454], 'Excellence,': [2463], 'Medical': [2466], 'Center,': [2467], 'New': [2468], 'Haven,': [2469], 'Conn.Address': [2470], 'correspondence': [2471], 'Dr.': [2473, 2494], 'Zimbrean': [2474, 2495, 2567], '([email': [2475], 'protected]).Dr.': [2476], 'Schilsky': [2477, 2569], 'served': [2479], 'speaker': [2482], 'Gilead': [2484], 'adviser': [2488], 'investigator': [2490], 'Therapeutics.': [2493], 'reports': [2496], 'financial': [2498], 'relationships': [2499], 'commercial': [2501], 'interests.References1': [2502], 'Coffey': [2503], 'AJ,': [2504], 'Durkie': [2505], 'M,': [2506, 2622, 2624, 2706, 2871], 'Hague': [2507], 'S,': [2508, 2532, 2626, 2758], 'et': [2509, 2533, 2627, 2669, 2711, 2761, 2784, 2809, 2872, 2898, 2930], 'al.:': [2510, 2534, 2628, 2670, 2712, 2762, 2785, 2810, 2873, 2899, 2931], 'genetic': [2512], 'study': [2513], 'United': [2519], 'Kingdom.': [2520], 'Brain': [2521, 2562], '2013;': [2522, 2945], '136:1476–1487Crossref,': [2523], 'Medline,': [2524, 2544, 2583, 2602, 2618, 2681, 2702, 2726, 2752, 2775, 2800, 2825, 2863, 2889, 2921, 2947], 'Google': [2525, 2545, 2565, 2584, 2603, 2619, 2646, 2661, 2682, 2703, 2727, 2753, 2776, 2801, 2826, 2848, 2864, 2890, 2922, 2948], 'Scholar2': [2526], 'Soltanzadeh': [2527, 2529], 'A,': [2528, 2893], 'P,': [2530, 2664], 'Nafissi': [2531], 'disease:': [2536, 2575, 2591, 2988, 3099], 'masquerader.': [2539], 'Eur': [2540, 2796], 'Neurol': [2541, 2797, 2884, 2943], '2007;': [2542], '57:80–85Crossref,': [2543], 'Scholar3': [2546], 'Kinnier-Wilson': [2547], 'SA:': [2548], 'Progressive': [2549], 'lenticular': [2550], 'degeneration:': [2551], 'familial': [2553], 'nervous': [2554], 'associated': [2556, 2631], 'cirrhosis': [2558], 'liver.': [2561], '1912;': [2563], '34:295–509Crossref,': [2564], 'Scholar4': [2566], 'PC,': [2568], 'ML:': [2570], 'review.': [2577], 'Gen': [2578, 2598], 'Hosp': [2579], '2014;': [2581], '36:53–62Crossref,': [2582], 'Scholar5': [2585], 'Dening': [2586], 'TR,': [2587], 'Berrios': [2588], 'GE:': [2589], '195': [2595], 'cases.': [2596], 'Arch': [2597], '1989;': [2600, 2798], '46:1126–1134Crossref,': [2601], 'Scholar6': [2604], 'Chung': [2605], 'YS,': [2606], 'Ravi': [2607], 'SD,': [2608], 'Borge': [2609], 'GF:': [2610], 'Psychosomatics': [2615, 2772, 2860], '1986;': [2616], '27:65–66Crossref,': [2617], 'Scholar7': [2620], 'Sagawa': [2621], 'Takao': [2623], 'Nogawa': [2625], "[Wilson's": [2629], 'olfactory': [2633], 'idiopathic': [2637], 'thrombocytopenic': [2638], 'purpura].': [2639], 'Shinkei': [2642], '2003;': [2643, 2861], '55:899–902': [2644], '(Japanese)Medline,': [2645], 'Scholar8': [2647], 'Shah': [2648], 'N,': [2649], 'Kumar': [2650], 'D:': [2651], 'ECT.': [2656], 'Convuls': [2657], 'Ther': [2658], '1997;': [2659], '13:278–279Medline,': [2660], 'Scholar9': [2662], 'Stiller': [2663], 'Kassubek': [2665], 'J,': [2666, 2781], 'Schonfeldt-Lecuona': [2667], 'C,': [2668, 2869], 'Clin': [2677], 'Neurosci': [2678], '2002;': [2679], '56:649Crossref,': [2680], 'Scholar10': [2683], 'Herring': [2684], 'NR,': [2685], 'Konradi': [2686], 'C:': [2687], 'Myelin,': [2688], 'copper,': [2689], 'cuprizone': [2692], 'model': [2693], 'schizophrenia.': [2695], 'Front': [2696], 'Biosci': [2697], '(Schol': [2698], 'Ed)': [2699], '2011;': [2700, 2723], '3:23–40Crossref,': [2701], 'Scholar11': [2704], 'Gonzalez-Estecha': [2705], 'Trasobares': [2707], 'EM,': [2708], 'Tajima': [2709], 'K,': [2710], 'Trace': [2713, 2719], 'elements': [2714], 'J': [2718, 2747, 2819, 2883, 2917, 2942], 'Elem': [2720], 'Med': [2721, 2844], 'Biol': [2722], '25(suppl': [2724], '1):S78–S83Crossref,': [2725], 'Scholar12': [2728], 'Lewis': [2729], 'DA,': [2730], 'Smith': [2731], 'RE:': [2732], 'Steroid-induced': [2733], 'syndromes:': [2735], 'report': [2737], '14': [2739], 'review': [2743], 'literature.': [2746], 'Affect': [2748], 'Disord': [2749], '1983;': [2750], '5:319–332Crossref,': [2751], 'Scholar13': [2754], 'Dubovsky': [2755], 'AN,': [2756], 'Arvikar': [2757], 'Stern': [2759], 'TA,': [2760], 'complications': [2765], 'glucocorticoid': [2767], 'use:': [2768], 'revisited.': [2771], '2012;': [2773], '53:103–115Crossref,': [2774], 'Scholar14': [2777], 'Bachmann': [2778], 'H,': [2779], 'Lössner': [2780], 'Kühn': [2782], 'HJ,': [2783], 'Long-term': [2786], 'GDR.': [2795], '29:301–305Crossref,': [2799], 'Scholar15': [2802], 'Modai': [2803], 'I,': [2804], 'Karp': [2805], 'L,': [2806, 2927], 'Liberman': [2807], 'UA,': [2808], 'Penicillamine': [2811], 'schizophreniform': [2814], 'Nerv': [2820], 'Ment': [2821], 'Dis': [2822], '1985;': [2823], '173:698–701Crossref,': [2824], 'Scholar16': [2827], 'Krim': [2828], 'E,': [2829, 2895], 'Barroso': [2830], 'B:': [2831], '[Psychiatric': [2832], 'disorders': [2833], 'clozapine': [2836], 'disease].': [2842], 'Presse': [2843], '2001;': [2845], '30:738': [2846], '(French)Medline,': [2847], 'Scholar17': [2849], 'Kulaksizoglu': [2850], 'IB,': [2851], 'Polat': [2852], 'A:': [2853], '44:438–439Crossref,': [2862], 'Scholar18': [2865], 'Kontaxakis': [2866], 'V,': [2867], 'Stefanis': [2868], 'Markidis': [2870], 'Neuroleptic': [2874], 'malignant': [2875], 'Neurosurg': [2885], '1988;': [2887], '51:1001–1002Crossref,': [2888], 'Scholar19': [2891], 'Knott': [2892], 'Dieperink': [2894], 'Willenbring': [2896], 'ML,': [2897], 'Integrated': [2900], 'psychiatric/medical': [2901], 'hepatitis': [2906], 'C': [2907], 'clinic:': [2908], 'antiviral': [2911], 'outcomes.': [2915], 'Am': [2916], 'Gastroenterol': [2918], '2006;': [2919], '101:2254–2262Crossref,': [2920], 'Scholar20': [2923], 'Minden': [2924], 'SL,': [2925], 'Ding': [2926], 'Cleary': [2928], 'PD,': [2929], 'Improving': [2932], 'multiple': [2940], 'sclerosis.': [2941], 'Sci': [2944], '335:42–47Crossref,': [2946], 'Scholar': [2949], 'FiguresReferencesCited': [2950], 'byDetailsCited': [2951], 'byStem': [2952], 'Cells': [2953], 'DiseaseCurrent': [2957], 'Stem': [2958], 'Cell': [2959], 'Research': [2960], '&': [2961], 'Therapy,': [2962], 'Vol.': [2963, 3009, 3028, 3047, 3063, 3067, 3072, 3080, 3092, 3112, 3120, 3131, 3140, 3144, 3146, 3151, 3158, 3177, 3199, 3210, 3219, 3229, 3234], '17,': [2964], 'No.': [2965, 3030, 3049, 3065, 3074, 3082, 3094, 3114, 3122, 3133, 3142, 3153, 3160, 3179, 3201, 3212, 3221, 3231, 3236], '8NEUROPSYCHIATRIC': [2966], 'ASPECTS': [2967], 'OF': [2968, 2976], 'MOVEMENT': [2969], 'DISORDERS1': [2970], 'August': [2971], '2022': [2972, 2989, 3006], '|': [2973, 3007, 3023, 3043, 3057, 3087, 3107, 3207], 'INDIAN': [2974], 'JOURNAL': [2975], 'APPLIED': [2977], 'RESEARCHA': [2978], 'approach': [2980], 'Practice': [2990], 'Guidance': [2991], 'from': [2995], 'American': [2997], 'Association': [2998], 'Study': [3001], 'Diseases7': [3004], 'December': [3005], 'Hepatology,': [3008], 'Publish': [3010], 'Ahead': [3011], 'PrintNosology': [3013], 'Phenomenology': [3015], 'Movement': [3019, 3024], 'Disorders7': [3020], 'January': [3021, 3205], '2020': [3022, 3042], 'Disorders': [3025, 3051], 'Practice,': [3027], '7,': [3029, 3081], '2Patient': [3031], 'Stratification': [3032], 'Using': [3033], 'Metabolomics': [3034], 'Address': [3036], 'Heterogeneity': [3038], 'Psychosis23': [3040], 'June': [3041, 3255, 3259], 'Schizophrenia': [3044], 'Bulletin': [3045], 'Open,': [3046], '1Sleep': [3050], 'Disease13': [3054], 'November': [3055, 3241, 3264, 3270], '2019': [3056], 'Current': [3058], 'Neurology': [3059], 'Neuroscience': [3061], 'Reports,': [3062], '19,': [3064, 3073], '11,': [3066], '165Expert': [3068], 'Review': [3069, 3148], 'Neurotherapeutics,': [3071], '11Expert': [3075], 'Opinion': [3076], 'Orphan': [3078], 'Drugs,': [3079], '6Wilson': [3083], 'disease6': [3084], 'September': [3085], '2018': [3086, 3106], 'Nature': [3088], 'Reviews': [3089], 'Primers,': [3091], '4,': [3093, 3143], '1Psychiatric': [3095], 'manifestations': [3096], 'possibilities': [3100], 'difficulties': [3102], 'treatment6': [3104], 'March': [3105, 3251], 'Therapeutic': [3108], 'Advances': [3109], 'Psychopharmacology,': [3111, 3218], '7Current': [3115], 'Options': [3117], 'Neurology,': [3119], '20,': [3121], '11Wilson': [3123], 'Related': [3126], 'DisordersRevista': [3127], 'Colombiana': [3128, 3135], 'de': [3129, 3136, 3184, 3190, 3195], 'Psiquiatría,': [3130], '47,': [3132, 3141], '4Revista': [3134], 'Psiquiatría': [3137], '(English': [3138, 3175], 'ed.),': [3139], '142,': [3145], '142International': [3147], 'Psychiatry,': [3150], '29,': [3152], '5World': [3154], 'Journal': [3155], 'Gastroenterology,': [3157], '23,': [3159], '30Multidisciplinary': [3161], 'tertiary': [3164], 'hospitals': [3166], 'diseaseGastroenterología': [3172], 'y': [3173, 3197], 'Hepatología': [3174], 'Edition),': [3176], '39,': [3178, 3200], '9Unidades': [3180], 'multidisciplinarias': [3181], 'en': [3182], 'hospitales': [3183], 'referencia': [3185], 'para': [3186], 'mejorar': [3187], 'la': [3188], 'atención': [3189], 'los': [3191], 'pacientes': [3192], 'con': [3193], 'enfermedad': [3194], 'WilsonGastroenterología': [3196], 'Hepatología,': [3198], '9Antipsychotics': [3202], 'trientine9': [3204], '2016': [3206], 'Reactions': [3208], 'Weekly,': [3209], '1583,': [3211], '1Journal': [3213], 'Child': [3215], 'Adolescent': [3217, 3224], '26,': [3220], '3Child': [3222], 'Mental': [3227], 'Health,': [3228], '10,': [3230], '1Hepatitis': [3232], 'Monthly,': [3233], 'Volume': [3238], '172Issue': [3239], '11': [3240], '01,': [3242], '2015Pages': [3243], '1068-1072': [3244], 'Metrics': [3245], 'PDF': [3246], 'download': [3247], 'Received': [3249], '24': [3250], '2015': [3252, 3256, 3260, 3265, 3271], 'Revised': [3253], 'Accepted': [3257], '15': [3258], 'Published': [3261, 3266], 'online': [3262], 'print': [3268]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1901528751', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 9}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 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