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[106], 'CST5': [107, 138, 150, 164, 178, 199, 220, 235, 255, 267], 'was': [108, 165, 257], 'shown': [109], 'to': [110, 124], 'mediate': [111], '(MET).': [114], 'We': [115], 'recently': [116], 'performed': [117], 'integrated': [119], 'genomic': [120], 'proteomic': [122], 'screen': [123], 'identify': [125], 'targets': [126], 'p53': [129, 142, 154, 162, 191, 216, 276, 289], 'suppressor': [131], 'CRC': [133], 'cells.': [134], 'Thereby,': [135], 'we': [136, 146], 'identified': [137], 'as': [139, 151, 242, 268], 'putative': [141], 'target': [143, 155], 'gene.': [144, 156], 'Here,': [145], 'validated': [147], 'characterized': [149], 'direct': [153], 'After': [157], 'activation': [158, 214], 'conditional': [161], 'allele,': [163], 'upregulated': [166], 'on': [167], 'mRNA': [168], 'protein': [170], 'levels.': [171], 'Treatment': [172], 'with': [173, 205], 'nutlin-3a': [174], 'or': [175], 'etoposide': [176], 'p53-dependent': [181], 'manner.': [182], 'These': [183], 'regulations': [184], 'were': [185], 'direct,': [186], 'since': [187], 'ectopic': [188], 'endogenous': [190], 'occupied': [192], 'conserved': [194], 'binding': [195], 'site': [196], 'promoter': [200], 'region.': [201], 'addition,': [203, 281], 'treatment': [204, 287], 'calcitriol,': [206], 'active': [208], 'metabolite,': [211], 'simultaneous': [213], 'resulted': [217], 'enhanced': [219], 'induction': [221, 298], 'increased': [223], 'repression': [224], 'epithelial-mesenchymal': [228], '(EMT)': [230], 'inducing': [231], 'transcription': [232], 'factor.': [233], 'Furthermore,': [234, 254], 'inactivation': [236], 'decreased': [237, 245], 'p53-induced': [238], '(MET)': [241], 'evidenced': [243], 'inhibition': [246], 'SNAIL': [248], 'migration': [251], 'p53.': [253], 'expression': [256], 'repressed': [259], 'SNAIL.': [261], 'summary,': [263], 'these': [264], 'results': [265], 'imply': [266], 'important': [270], 'mediator': [271], 'suppression': [274], 'cancer.': [279], 'they': [282], 'suggest': [283], 'that': [284], 'combined': [286], 'activating': [288], 'pathway': [294], 'may': [295], 'function': [296], 'via': [297], 'CST5.': [300]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1901238969', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 9}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 9}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}], 'updated_date': '2024-12-15T09:16:40.448041', 'created_date': '2016-06-24'}