Title: Affective Illness in Veteran Twins: A Diagnostic Review
Abstract:The authors systematically reviewed diagnoses in the Veteran Twin Registry and found 62 pairs of twins (69 individuals) in which one or both had affective illness, a frequency of .22 percent (monozygo...The authors systematically reviewed diagnoses in the Veteran Twin Registry and found 62 pairs of twins (69 individuals) in which one or both had affective illness, a frequency of .22 percent (monozygotic [MZ] concordance = 33 percent, dizygotic [DZ] concordance = 0 percent, and MZ/DZ ratio ≥ 11.5). In 40 of the 62 pairs, one or both twins had unipolar depression (MZ concordance = 40 percent, DZ concordance = 0 percent, and MZ/DZ ratio ≥ 8). Bipolar depression was present in 22 pairs (MZ concordance = 20 percent, DZ concordance = 0 percent, MZ/DZ ratio ≥ 3.2). The data indicate that both environmental and genetic factors are important in the etiology of affective illness and present evidence that unipolar and bipolar illness are separate entities.Read More
Publication Year: 1974
Publication Date: 1974-11-01
Language: en
Type: review
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 52
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