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[48], 'three': [49, 87], 'times': [50], 'daily': [51], 'for': [52, 85, 181, 234], '1': [53], '5': [55], 'days.': [56], 'The': [57, 176], 'development': [58], 'tolerance': [60], 'dependence': [62], 'were': [63, 67, 100, 138], 'recorded': [64], 'daily.': [65], 'Brains': [66], 'dissected': [68], '30': [69], 'minutes': [70], '(1-': [71], '5-day': [73, 89, 127], 'groups)': [74], '1,': [76], '3': [77], '7': [79], 'days': [80], 'after': [81], 'last': [83], 'administration': [84], 'other': [88, 202], 'groups': [90], '(groups': [91], 'under': [92], 'withdrawal).': [93], 'Specific': [94], 'alterations': [95, 179], 'genes': [98], 'expression': [99, 149], 'ascertained.': [101], 'In': [102, 141], 'amygdala,': [104], 'an': [105, 145], 'up-regulation': [106], 'prodynorphin': [108], 'pronociceptin': [110, 118], 'observed': [112, 180], '1-day': [115, 135, 152], 'group;': [116], 'moreover,': [117], 'kappa': [121], 'receptor': [123], 'mRNAs': [124], 'group': [128, 137, 153], 'both': [130], 'peptide': 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